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<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFI5</accession>
    <name>U1MFI5_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00005</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87864.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87864">
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        <property type="gene ID" value="J07HX5_00005"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079331_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="12174" checksum="07AB0C49D786B491" modified="2013-11-13" version="1">MLVGLAVAHAAHTAVTHAGLGAGVRYGAVPLVALPAIVVYAVAFRLVETLVIGLPAVGQPTELTVVHAGVAVAFVVAYIGIERGTYKRSKRLYVALLNTTAPPAATQLTTREEYDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFL5</accession>
    <name>U1MFL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00060</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ERG87919">
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        <property type="gene ID" value="J07HX5_00060"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783888_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7530" checksum="1EB28DC8832EECBF" modified="2013-11-13" version="1">MQEKTDTLRELYLEITDEETLTEPQEESPSRAPVESVDAAVDEDVADIARHDGLDDAVEDLEAVEPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFS3</accession>
    <name>U1MFS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00150</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="family name" value="Hormone-sensitive_lipase_like"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88009">
        <property type="protein sequence ID" value="ERG88009"/>
        <property type="gene ID" value="J07HX5_00150"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="3">
        <location>
            <begin position="87"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="34760" checksum="2B28AEB1E31D7372" modified="2013-11-13" version="1">MSQSDERRAESPSPEAQELLSALEEAGAPDLATLSVEQARALLGDLFTPDGEPEPVESVTEQKIRAYGRDIRVRIYDPVPDATLPAVVYFHGGGWVCGNLDTHDSVARALAARGETVVVSVDYRKAPEHKFPAAVEDAHTATKWVAANAGDIGAGNGLAVAGESAGGNLAAVVAQLANDSALGAPAIDHQLLLYPVTNHSYDTTSYETNREGYFLTRRAMVWFWNHYLRDDALGADGQNPLASPLHGALAGLPPATVFTSGYDPLRDEGFQYVEALTEAGVDVEHTNYEGAIHDFANMVDLDGAPSLGEFSEQVLDDAAAALQAAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGE6</accession>
    <name>U1MGE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00427</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88284">
        <property type="protein sequence ID" value="ERG88284"/>
        <property type="gene ID" value="J07HX5_00427"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1212587_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="228" mass="24845" checksum="8E481A01D21C551C" modified="2013-11-13" version="1">MYSDWSPSNQFGWVVSLLLAVVVLIGLAGGSIVIVNLVDSGPPDPPSGVEAAERLDDLDTIELVGNRTRQIDGNTSWAVTERAQRIGTGEFRDEIVAAGSERANATFGPGSLSVSNGSVRYIYNANTDRLLRSEVNESEQSERSENVRNLFAAVGDELDQSVPIFPTFSPSESSNSSTEWRDTAVTVEYCGTETVAGRDSYVLSWSRDRRRAAGQXXXXXXXRTSVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGW2</accession>
    <name>U1MGW2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">S-adenosylmethionine synthase</fullName>
            <shortName evidence="14">AdoMet synthase</shortName>
            <ecNumber evidence="6 14">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mat</name>
        <name evidence="15" type="ORF">J07HX5_00624</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 14">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the AdoMet synthase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="6 14"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88479">
        <property type="protein sequence ID" value="ERG88479"/>
        <property type="gene ID" value="J07HX5_00624"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057642_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00136">
        <property type="entry name" value="S_AdoMet_synth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042543">
        <property type="entry name" value="AdoMet_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027790">
        <property type="entry name" value="AdoMet_synthase_2_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042544">
        <property type="entry name" value="AdoMet_synthase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002795">
        <property type="entry name" value="S-AdoMet_synthetase_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36697">
        <property type="entry name" value="PTHR36697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01941">
        <property type="entry name" value="AdoMet_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="137"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ERG88479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="400" mass="43087" checksum="FC0DC2EF6A2BDDE6" modified="2013-11-13" version="1">MTARNIHVQRASGRAVEDQQVEIVERKGLGHPDSICDGVAEAVSRALARTYRERFGTVLHFNTDETQLVAGTAAPAFGGGEILEPIYLLVVGRATKQYEGERIPAETIALRTARAYLDDQFPHLDVGSDVIVDVKLGEGSGDLQEVFGEHRTVPMANDTSYGVGHAPLTETEQIVRETERRLNAEHGRERLAVGQDIKVMGKREGDQIDVTVAAAVVDEYVSDMAAYRSVVAEIEESVAEIAAGLTNREVTVYVNTADDYETGAIYLTTTGLSAEQGDDGSVGRGNRANGLITPNRPMSLEATSGKNPVNHIGKIYNLLSTELAHAVADEVDGVRQLQVRLLSQIGEPIDQPHVADVTVVPDDGYTIDAVSTGIEAVIDRELADVTTITDQVIDGKLSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGY7</accession>
    <name>U1MGY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SUF system FeS assembly protein, NifU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00665</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88519">
        <property type="protein sequence ID" value="ERG88519"/>
        <property type="gene ID" value="J07HX5_00665"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="140" mass="15388" checksum="836F55057D19B862" modified="2013-11-13" version="1">MGIGGSDIYRQQILDHYKNPRNYGELTEPTFSHVGENPMCGDRIEFDVVLDDDGRIEQVAFQGDGCAISQASASLLSEKLPGRTIEELQAMDRDDVIELLGVDISPMRVKCAVLAEKVAQDGAEIYRGEKDDEPSVLDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHN6</accession>
    <name>U1MHN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00985</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88839">
        <property type="protein sequence ID" value="ERG88839"/>
        <property type="gene ID" value="J07HX5_00985"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_16_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="40"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="19300" checksum="73B51BA8EBACA39C" modified="2013-11-13" version="1">MGFHTFDTERADGLNDPERFRYGSREELLQHLPERPARLLDLGSGTGFYTRELAPYAGTVYAVDIQSEMHRLHREAGVAEPVQLVTADGEALPFAAGAVDAAVSTATFHESASPEALADLARVVDGRVVIVDWSGQGSGDAGPPVDQRFTAAEAESLLTDAGFETPVVAERAETFLLVGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIW2</accession>
    <name>U1MIW2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01512</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89354">
        <property type="protein sequence ID" value="ERG89354"/>
        <property type="gene ID" value="J07HX5_01512"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2366092_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10045" checksum="57059228C83C10A6" modified="2013-11-13" version="1">MDLPKNSSNADVSSADLRECYFSNATLDNANLSGVDLRRADLSEANLERATVVEVNLFDADLTKITPDGACIEAVQINDRTGLINGQGNVTASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJG4</accession>
    <name>U1MJG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01789</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89619">
        <property type="protein sequence ID" value="ERG89619"/>
        <property type="gene ID" value="J07HX5_01789"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104913_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043815">
        <property type="entry name" value="DUF5797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19110">
        <property type="entry name" value="DUF5797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="17023" checksum="42B177C5857BD601" modified="2013-11-13" version="1">MALDEQARDRLADILALQPTKNGTLQAQWGLDSGSAVHQYLEAELGEYYYRDEDSLIRATPAAEALVGEGTTDQTVAGTRLHRRVFNDLPGTDAEPQSVVATLHVVRETGDDPGVDAVRSTLHELVDRGVVERVQRTVPTFRRAVDRESITIAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJG7</accession>
    <name>U1MJG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, contains C-terminal CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01794</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89624">
        <property type="protein sequence ID" value="ERG89624"/>
        <property type="gene ID" value="J07HX5_01794"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1514568_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005104">
        <property type="entry name" value="WHTH_HrcA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03444">
        <property type="entry name" value="HrcA_DNA-bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HrcA_DNA-bdg" evidence="1">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="177" mass="19051" checksum="2B3347FFC9553F5A" modified="2013-11-13" version="1">MSSIELTPSQRTILQELVNLYREQESAIKGETIAAEVDRNPGTIRNQMQSLKALQLVEGVPGPKGGYKPTSAAYDALQIQDLDQAADVPLAHNGEPVDHANVERIDLTNVHHPQECRAQVRLQGSIGDFHEGDSVTVGPTPLSKLQIDGTVDGQDDTANAIILSIDGMEAPTETPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJX6</accession>
    <name>U1MJX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01981</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89809">
        <property type="protein sequence ID" value="ERG89809"/>
        <property type="gene ID" value="J07HX5_01981"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2228631_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11145" checksum="324B8B890D5C6011" modified="2013-11-13" version="1" fragment="single">VDTPTASEPVAVFPGDVAGAVALSFAGLAVPRGAYRSVTVVRSGFRSVIGDRYPGRPGANRGVPRGQALRLHRSGTHNTQQVNLFPLDLPATGRLEFTPERLVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV19</accession>
    <name>U1MV19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00056</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87915">
        <property type="protein sequence ID" value="ERG87915"/>
        <property type="gene ID" value="J07HX5_00056"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_14_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="30624" checksum="27076293358E6767" modified="2013-11-13" version="1">MGLSSGIYFIAANPLVSELFPDNVGAAIGVHGLSSQVAAVTVPLGISVVLIDGNWRSIFLIIAGIAATATAALIWAARRTDLPEAGTADRSLGAATRAQWPTILTGIAFVGAAGFLWNGLFNLYGDYLTVAKAIDAETGRLMLSVMFAAGLPAFVVTGWLADRVPNVPLLLIISSGFVVAVGGLTLVDGIAAIVAASLVIGYTFHSLLTAVDTYMLSSLPDRHRASAYAVFSAVMMGVQAFGSGVVGTAVAGGLAYTTVFQLLTVGVGAMLVLLFGLYRVGRLPAGGRTGPVPAPERAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVC1</accession>
    <name>U1MVC1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00191</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88050">
        <property type="protein sequence ID" value="ERG88050"/>
        <property type="gene ID" value="J07HX5_00191"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144574_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043941">
        <property type="entry name" value="EMC6-arch"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19094">
        <property type="entry name" value="EMC6_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="111" mass="11402" checksum="31E72B788E83FC28" modified="2013-11-13" version="1">MATETSDGVSENGADATTEGVSPYVRSVTVTTLATVSGIGAGIASTLLIDGVGGPLGLVILITAILAQFPLLRAIGIDTDSFGTKDKLYIGFMSFALWFISWAIFLTTGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVC9</accession>
    <name>U1MVC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase-like component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00201</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88060">
        <property type="protein sequence ID" value="ERG88060"/>
        <property type="gene ID" value="J07HX5_00201"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7 8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="11">
        <location>
            <begin position="4"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="10">
        <location>
            <begin position="359"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="469"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="505" mass="54529" checksum="E5A50FD6D639E264" modified="2013-11-13" version="1">MSIHVAVIGAYGSAGSAVADRLVTAPNVELSLIDDGDPGGGLCILRGCMPSKELLSTAAHRYQARHDDRLSGEIPEVDLETAIEQKNDRTLGWAGHRREQVHEWADRDDVSFYNAGAEFVDDDTLVVNGEQIEPDYIVVATGSRVNIPDIPGIGTVDRMTSADVLDATSLPDSGIVIGFGYVGLEMTPYLVEAGGMDVTVVEHDDRPLDEADPAFGDEILDIYRDDFDVDVVMNALEQRLEQTDDGGVRLSLSTPDGEQTIEADTLFCFTGRTPNIDRLGIEAAGIDPSGEWVADTMRARDNNRVYVVGDANEREPILHIAKEQGQTAAENILRQTAGTELEPYEATHHHVVFSGLGVYPFARVGHTGASARDAGHNVLEVTRAASDDGIFKSKDVPAGLSRLVVDRDDGTVLGYQGLHYHADTMAKTAQLLVELELDVRTVPDRAYHPTLPELLDGLFGEAADAVEEGLKNTDNTIGDDQTRPEQTDQSDSPVDGQASALETDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVI9</accession>
    <name>U1MVI9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00124</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87983">
        <property type="protein sequence ID" value="ERG87983"/>
        <property type="gene ID" value="J07HX5_00124"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1953236_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="15068" checksum="4A0C385096335739" modified="2013-11-13" version="1" fragment="single">KTLELKPVQSNAHKLTKLQETREAYQQALCDALNARCTTQTEANDVVVNYDLNGYAKNALRKYVPQLTTTYNAGEIHDDHPVRFTNEGLRLDHKPENAIEWYVRIPYHEDYHFWIPAQPNPEQRDCSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVJ2</accession>
    <name>U1MVJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00273</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88130">
        <property type="protein sequence ID" value="ERG88130"/>
        <property type="gene ID" value="J07HX5_00273"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150429_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15777" checksum="70A614D47F886C76" modified="2013-11-13" version="1">MSVVHSNDTGTIALAFSLAAIREVEDPAMVFEDARQWSRHVGIIGDDPAAIEAFLTEHDLQQDFDQGDRDRWLALAELATASPAPRLVHIGAGPERRPFAEEAGWEYLTVDEAAASADWSLATEPAAPDAEPEQGXXXXXXXLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVK0</accession>
    <name>U1MVK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00134</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87993">
        <property type="protein sequence ID" value="ERG87993"/>
        <property type="gene ID" value="J07HX5_00134"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128030_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="13632" checksum="1658AE6EC2AEC14C" modified="2013-11-13" version="1">MNADETIAAYYDALRAGEPLGPYFAEGQPDDDALVKYGLSERLVGDTEIRAGLRRQTETTTDWAVTSHALQVCSRDTHGWFSDTVSMAWTDIETAIRYEFETRWSGTLAQTADDGGLSGCTSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVT6</accession>
    <name>U1MVT6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00373</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88230">
        <property type="protein sequence ID" value="ERG88230"/>
        <property type="gene ID" value="J07HX5_00373"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037493_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021516">
        <property type="entry name" value="DUF3179"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11376">
        <property type="entry name" value="DUF3179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="326" mass="35105" checksum="05823B21EA494DCF" modified="2013-11-13" version="1" fragment="single">APKDGIPAIVNPSFGADWSGFAAETRSRFGSTNTIAPRLAEDDLVVGVTRDGAARAYPLKLLNYHEIVNDTFGGPLLVTYCPLCRSAIVAERRANGEPTVFGVSGLLYRNALVMYDEATGSNWSQILAQAITGELTGERLELLPSTLTTFGEWRASHPNTAVLRPPPESDTLSAGSGVRNYTTDPYPGYDQSSQIGIGGEFDDDRLGPKTEVVGVAVAETARAYTTETIETEGLINDTVGGLPIVVTNTPDGTPIAWSRRVGDETLSLRIADERHLAGGGSQWRRDTGVAVDGPFEGERLAQANSVSALFWFAWLDFYPETELYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVU6</accession>
    <name>U1MVU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00383</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88240">
        <property type="protein sequence ID" value="ERG88240"/>
        <property type="gene ID" value="J07HX5_00383"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="285" mass="29718" checksum="A56A181CB50CBEDC" modified="2013-11-13" version="1">MPSETVEAPEFTAEAIHYVDDPSFDPETVALVTGAASGIGRATALALAANGLTVAGVDVDEAGLAETIGETETLDTAGRIEPLPADLTDDAAIEAAVEAATKLGSLSYVANIAGFQHIDPIEEFPMDTYDRMHAVMVRAPLYLSQLALPAIRESGDGTGCIGNMASVHGHYVTAEKVGYNVSKFALRGLTQSIAAEGDGEVRSFSVSTGYVATPLVVDQIPDTAASRGLSEREVVEDVLLGQARRKELMAPVDVANLFVLGFSELATHLNGGDLLFDGGMTGTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW04</accession>
    <name>U1MW04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ornithine cyclodeaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00306</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88163">
        <property type="protein sequence ID" value="ERG88163"/>
        <property type="gene ID" value="J07HX5_00306"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="PTHR13812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="330" mass="34337" checksum="3F8CE3FD0EA513A0" modified="2013-11-13" version="1">MTTVRMLHSDDLADLATPSEYVEAVRAGYKERGTGAPAAPRTLLAAADPPGVLTGYLAVLPEAGAMGGYTYAAGFTDRDAHFTLPLFDAETGAPLAILDGAGLNPYKTGAVGAVGTDALARADATRLAVIGSGTQARGQLRATAAVRELDHVAVYSPTPDHREAFASEEGARLDVPVEAVASSEAAVREADIVVTATTASEPVFAERQLAPGTHVTAVGQYHPDRHELDAETIARSRYVLDLRDRADQDAGSYIAAREAGAIDDGHVHAELGEVLTGSRPGRTGEEITVFDSGGTAIETVAVGKLLYDKAVERGLGEMVEFAPASEAMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW49</accession>
    <name>U1MW49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00351</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88208">
        <property type="protein sequence ID" value="ERG88208"/>
        <property type="gene ID" value="J07HX5_00351"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396204_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="4">
        <location>
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            <begin position="622"/>
            <end position="641"/>
        </location>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
    <sequence length="695" mass="74747" checksum="7362803F00DFEE65" modified="2013-11-13" version="1"> </sequence>
</entry>
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</entry>
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</entry>
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    </evidence>
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</entry>
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    <accession>U1MWL3</accession>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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</entry>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG88368.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="67" mass="6702" checksum="28539EAED8B8F2D8" modified="2013-11-13" version="1">MMAHIRAAFRREDPGALLAVGLVLSVVGLVTAGDLTGQGIGLIIGGAVQVVGVGTMVGTAVWSDIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP3</accession>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="38" mass="4339" checksum="4959F977DDAB9D4B" modified="2013-11-13" version="1" fragment="single">MTDRQEIRQLDQRTVEQIAAGEVVERPASAVRELIENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWQ6</accession>
    <name>U1MWQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligoendopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00548</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88403">
        <property type="protein sequence ID" value="ERG88403"/>
        <property type="gene ID" value="J07HX5_00548"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1672847_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="2">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="158" mass="17846" checksum="B95879AB54C9DF7D" modified="2013-11-13" version="1" fragment="single">MSSVRERSTVDEGYTWELEALYATDEEWETGFANAQAQLDELRAYEGRAVEDPATLLETLETYESVMRAVANVTAYARMRRDEDTTDDDSQAMASRGQSLRAEAKSAGSFLEPEIQTLEQETVSEFIATEPALAEYEHYFDDILRTKQHTRSAAVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWR8</accession>
    <name>U1MWR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00741</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88595">
        <property type="protein sequence ID" value="ERG88595"/>
        <property type="gene ID" value="J07HX5_00741"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_216660_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="47" mass="5372" checksum="C5D75DFBB49B1F7D" modified="2013-11-13" version="1">MHPNVDIPWSLHAQLKEWAEETDPTLTESYTKLVKAGLNNVEHPDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWS0</accession>
    <name>U1MWS0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartokinase</fullName>
            <ecNumber evidence="7">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00563</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88418">
        <property type="protein sequence ID" value="ERG88418"/>
        <property type="gene ID" value="J07HX5_00563"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_6_5_2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="261"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="393" mass="41857" checksum="AEA52E51CC5C7E24" modified="2013-11-13" version="1">MRLVAKFGGTSVADGDRVARAASSIAAAVEQDHEVAVVVSAMGQTTDELLSEITFDASERDRAEIVSMGERTSVRMLAGALNARGIEATTVEPGCDEWPIITDEYGEVDIEATRRRGSWCLEQMKTGVVPVITGFLAQDQDGQTTTLGRGGSDTTAVMLGNYLEADAVAIVTDVEGVMTADPTVVEGARNVGKISVDELRSLSFRGAEVVAPSALAYKTDDLDVRVVHHRHGDLLTGGTRVEGEFETLVDLQEQRLVCLTVAGRAIRNQPGVLAALSSAVGAAGINVETVSSGLDSVTLYVEESDGKDAETLLHREVVGDDALSSVTVEEGIAVIRVAGGNFEQRSGAVQQVLEPLDRERIYLHDVVTSASSVSVFVDWEDRERALETVREVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX76</accession>
    <name>U1MX76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator containing an HTH domain fused to a Zn-ribbon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00734</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88588">
        <property type="protein sequence ID" value="ERG88588"/>
        <property type="gene ID" value="J07HX5_00734"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162441_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038767">
        <property type="entry name" value="Transcriptional_reg_pdt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40663">
        <property type="entry name" value="PTHR40663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10823" checksum="B47C3A151784CBBF" modified="2013-11-13" version="1">MEQTTREQIADRLRERPQSPSALGREFGIGADEAVAAVRHVARSVAAANEQLLVAPPACQDCGFDRFDEPASRPSRCPDCHSEAITEPVFRVETTTNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX94</accession>
    <name>U1MX94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00911</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88765">
        <property type="protein sequence ID" value="ERG88765"/>
        <property type="gene ID" value="J07HX5_00911"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1762538_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15361" checksum="5A8E8BEA6EE22273" modified="2013-11-13" version="1" fragment="single">MDLQLEGNAALCTAASSGLGYASAAALAREGADVAVCGHTPAHVDRAERRLREIGPGEVVATEADITDPEELSAFVAATVDAFGGLDHVITSAGGPPSGPFLNTDDQDWYHAYEMLVMSVVWTLQEAQPHLAANGGSIVAITSRTVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXC3</accession>
    <name>U1MXC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00941</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88795">
        <property type="protein sequence ID" value="ERG88795"/>
        <property type="gene ID" value="J07HX5_00941"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="9"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="326" mass="35293" checksum="04454399A131EBAA" modified="2013-11-13" version="1" fragment="single">MSAGSDPLLAVDDLHVYFQTDAGDDVQAVDGVSFRVHPGKTTAIVGESGSGKTVTSEAITRLFQQPPGYLPQGSVMLDGQDLIELPDDELRSVRGNKISHIFQNPQGALNPVYTVGWQLREAIMLHQDVSKEQANEQAIRLMNQVGIPEAASRVDDYPHEFSGGQKQRVIIAMALACEPELLIADEPTTALDVTIQAQILDLLRELQSERNMAMLFITHDLGVVAEVADRVIVMYAGKIMERGSVDDVFQTPAHPYTRALLECLPGQGELGGIPGQLPDPKQPPSGCRFASRCSHAVASCTTGDQPPLYEVQDTSDHTASCIHFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXG7</accession>
    <name>U1MXG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00839</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88693">
        <property type="protein sequence ID" value="ERG88693"/>
        <property type="gene ID" value="J07HX5_00839"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783891_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007354">
        <property type="entry name" value="CruF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04240">
        <property type="entry name" value="Caroten_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7458" checksum="158575F0F0ECCB4A" modified="2013-11-13" version="1">MLDLAFDADALRERLQSCEHVLDDMVSLVLLWGGINGWFGNWLPAAVAVVIGLGLVWTDQFDANLLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXL3</accession>
    <name>U1MXL3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00894</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88748">
        <property type="protein sequence ID" value="ERG88748"/>
        <property type="gene ID" value="J07HX5_00894"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2176187_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_12" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="12130" checksum="3CD2C2663CC6C7B1" modified="2013-11-13" version="1" fragment="single">RIGIIAPYRARVAEIGRRIGDEITVDIIDWFQGSSKAVIVVSFVATESLDSPIFDDYRRVNVALTWAKHAVVLVGDGETLRTDGTYRRMVEWAESEGETETDNNAGAGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXL4</accession>
    <name>U1MXL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01016</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88870">
        <property type="protein sequence ID" value="ERG88870"/>
        <property type="gene ID" value="J07HX5_01016"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1021160_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="28178" checksum="7516AD1EB030DA47" modified="2013-11-13" version="1" fragment="single">QLEAIETAGFSQSLSWDLELTVDESGDKPVLALTADITQDSENWEQLLAELEQTVDTNLATDISLETNGDRIVGDLSVAVANDDWVDKLLGSGLTGSSLSPDEAQLLTAVDSAGFERAAVDVNAADGTVTGAVAFDSLGPLFAELFDTTAAVTIDELVIQSESPATAYVHVSSETMSVDTLTEAGLIEQGTTTVEDADSVDRTFPSVDAGALTERADELGLADDTTAAQLLDSAGRGSDDIGGTPLMFGAAGALAVLVIGMSAGLYLERRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXQ2</accession>
    <name>U1MXQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01061</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88915">
        <property type="protein sequence ID" value="ERG88915"/>
        <property type="gene ID" value="J07HX5_01061"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1859316_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14982" checksum="D50CAB13AE67CB3D" modified="2013-11-13" version="1" fragment="single">WNCKRYSKVRFPSMSEGGFFESDNETQCVGVQLSVTNETDDPDGFVRSVTGSGVSLTTPGLTLLADGTSDDITMHARSKYSHLESVSPEETVEATLLHTASPQTFSYTLEAKEGSQHTYSIKGDEDLEIRLTELNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXU6</accession>
    <name>U1MXU6_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Phosphate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01115</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88965">
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        <property type="gene ID" value="J07HX5_01115"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBP_domain" evidence="4">
        <location>
            <begin position="41"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="35929" checksum="B5361EAE9467A2AC" modified="2013-11-13" version="1">MRSDGSGDVGRLSRRETLVTLGGAGVVALGGCVSSGSSSGDSSEQLTGTLRVSGSSTVHPVAQEVGRMFAGELHPEVNFNLSKDGSGAGFRNYFIPGSADINNASRRIKDSELQDCRDNDINPIEFQIAQDALTIVANNENDWVDEMEVSTIGEIWDPETAPETWADVNSSWPDLEFDLFGAATTSGTFDYFTERVVGEEDSIREDYEGTERDDQVAAGVAGDQAAFGYLPFAYYVNNPDQVKAISVIGESGEAVAPSLTAAQSGEYPLARPLFFYVNDNKLAEKQTLQEFVRYYIEQAGEEFISEVGYVASTQEQVQSNLDKLDQTLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXW2</accession>
    <name>U1MXW2_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01135</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88985.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88985">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="137"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="303" mass="33380" checksum="BBF7E93E5EF75BED" modified="2013-11-13" version="1">MTETSARATECCRTNVDRNEVEEVTVELVPWAPVESCTYDRVLFAPKPYTPADVNMERLVRGLAATVPEGHCYVAGTEPTGIDAYAELLEALCEEVIQVETDADCTVYRATRPPDFTPGNQIEEREFRSSVGDYTCRFVTIPGLFSWEELDTGTEALLRHTSVPDGAQMLDLACGYGPVGAFVGARTDCEVYATDDSVLMTTFARRNYERNGVTPAAVETDDCLDAFPDRTFGAILLNPPTHAGKGVTWKMFQSACAALADDGELWLVYNEIMNYERVLRSEFGLNTKVVASVETFDVTVARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY27</accession>
    <name>U1MY27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nicotinate-nucleotide pyrophosphorylase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_01059</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88913">
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        <property type="gene ID" value="J07HX5_01059"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_C" evidence="2">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9261" checksum="A896099CD583A535" modified="2013-11-13" version="1">MEIEQPVDAPRAAAVGADAVLLDNMSPAETERAVSLVTDHETPPTLEASGGITLETAADYAVTGVDVVSMGSLTHSTPTLEYSFRTGAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY38</accession>
    <name>U1MY38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01075</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88928">
        <property type="protein sequence ID" value="ERG88928"/>
        <property type="gene ID" value="J07HX5_01075"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313091_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="60"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="209" mass="22307" checksum="FB853EC2FE60D5C8" modified="2013-11-13" version="1">MRRADGDYTQFSDSLTIVFVTANTLVFLTQVLLLIVTAPAAFEFWFVAQVQPTPGIVLGPLSHEDPAHFVLNMLLFGLVGWAVERRIKRRAYGMFVAITAYLPVYLQVGVSYLVTGETGTMGFSGAIYALVPLYAIVQTSELLRDGDGGVGHDTKLPAAVLAIVVTAAIPLLVGGQLSVASDPAEPARVAHATGYLSGLLYGLIIVLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY98</accession>
    <name>U1MY98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01143</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88993">
        <property type="protein sequence ID" value="ERG88993"/>
        <property type="gene ID" value="J07HX5_01143"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090889_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="24130" checksum="D98F9886FF7C9710" modified="2013-11-13" version="1">MRSAELLDLLGNTNRRRILRLLAQRPYYVTEISDALGVGPKAVIDHLEKLEAAGLVESRTDDRRRKYFSIARHVRLEVTVSPYEFGAKSAYPRRSRPDTAREHLSISLDATEKRRDVRELIQTLRELEDLDRELSLAKRWVEGRLTELREELGETLETDPRLVGSVLAALADGPITVAAISEEIGADTPQIAAVLERLECEGIACQDEDGWQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYA7</accession>
    <name>U1MYA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01153</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89003">
        <property type="protein sequence ID" value="ERG89003"/>
        <property type="gene ID" value="J07HX5_01153"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073601_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="274" mass="30272" checksum="E27B05D0DCB46D98" modified="2013-11-13" version="1">MYGVVTRNQPELTWGAFDRGFYEVKDVTGRRESPTAAGTNMVSCHGDSAAAQDDALVPVSKQGEPATRDRQYFDWGYACPTHADYREELLGLLEDCGAVTEDVRLDDVGFPRAEYCFCDRCQRRFANSQFADRAAWRASVITSFVADARERVPGELSLTLYPDPMPGHLYERSGLDLAALEDHVDRFVVPLYDTAYGTTYWLEALASGFVDRLDTPVSIELYAVDVSVEALTHAAEVAGAYADEVYFAYDATAGRAAVEQLRADESDTPDTDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYE7</accession>
    <name>U1MYE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01349</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89195">
        <property type="protein sequence ID" value="ERG89195"/>
        <property type="gene ID" value="J07HX5_01349"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930095_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="63" mass="6760" checksum="FED92301AC606408" modified="2013-11-13" version="1">MLTDAQLEAMTAAVENGYYDIPRDISTAELGDQLGISDQAVTERLRRGISTLAANTMLAKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYF3</accession>
    <name>U1MYF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hemolysin related proteins containing CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01354</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89200">
        <property type="protein sequence ID" value="ERG89200"/>
        <property type="gene ID" value="J07HX5_01354"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="27"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="235"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="300"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="451" mass="49255" checksum="37EA4F367D7842B7" modified="2013-11-13" version="1">MQQPVTAPDELPVTVGSVEVFGSSLPDPLFAALGLAVILVLVLLSGLFSSSEIAMFSLPDHRIASLADESAAGTTLTALKSDPHRLLVTILVGNNLVNVAMSSIATGLLGYFMTSQSRAVFTATFGVTALVLLFGESAPKSYAADNTESWALRVARPLKAAAVVLWPLIAVFDRLTRLVNRAVGGEEPIESSYVTRQEIEEMIETGEQAGVLDEDERELLQRVLRFSRTIVKEVMTPRLDMTTVSTSASLEEVIETCIQSGHERVPVHDGDVDNIIGVAHMKDLVRELNYGERDVELEDLVEPTLHVPESKNVDELLTEMREQRLNLVIVIDEFGTTEGLVTIEDIVEEVVGEILEGEERAPITVADDDTATVRGEVSIDELNEQLGIDLPEGEEFETVAGFIFNRAGRLVDEGETIEYEGLAIQVESVENTRIRRVRIAGLTAYRETSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYG8</accession>
    <name>U1MYG8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">V-type ATP synthase beta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">V-ATPase subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpB</name>
        <name evidence="8" type="ORF">J07HX5_01220</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 6">Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89068">
        <property type="protein sequence ID" value="ERG89068"/>
        <property type="gene ID" value="J07HX5_01220"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022916_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="PTHR43389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab" evidence="7">
        <location>
            <begin position="75"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="420" mass="46426" checksum="097176CA829D3CEC" modified="2013-11-13" version="1">MFEGTSGLDRDASVQFVGETLKMPVTEDLLGRVLDGSGRPIDDGPEVVPERRQDIVGKAINPFSREYPEEFIQTGVSAIDGMNTLVRGQKLPIFSSSGLPHNDLALQIARQASVPEEQADDGDGDGSEFAVIFGAMGITQEEANEFIDDFERTGALERSVVFTNLADDPAVERTVTPRLALTTAEYLAFEKDYHVLVILTDMTNYCEALREIGAAREEVPGRRGYPGYMYTDLAQLYERAGRVKGEDGSITQIPILTMPSNDITHPVPDLTGYITEGQIIVDPELNSKGVEPPVDVLPSLSRLMDDGIGEGLTRGDHGDVADQLYAAYAEGEDLRDLVNIVGREALSERDNQYLDFADAFETEFVQQGFETGYEIEETLGIGWNLLSMLPREELNRVGQEYIEQYYRDEQEETEAVTADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYG9</accession>
    <name>U1MYG9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Triosephosphate isomerase</fullName>
            <shortName evidence="2">TIM</shortName>
            <shortName evidence="2">TPI</shortName>
            <ecNumber evidence="2 3">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tpiA</name>
        <name evidence="4" type="ORF">J07HX5_01370</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="2 3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89215">
        <property type="protein sequence ID" value="ERG89215"/>
        <property type="gene ID" value="J07HX5_01370"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104921_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_A">
        <property type="entry name" value="TIM_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022891">
        <property type="entry name" value="Triosephosphate_isomerase_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="197"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="217" mass="21435" checksum="F6B24D9EC21030A4" modified="2013-11-13" version="1">MFVLVNLKAYAVDPAEIARAAAAVSTADVSVDVRLAVAPQAAHIERVAATDIEAWAQHVAPIDQGSHTGHVRAEAVADAGAVGTLLNHSERRLQLGAIETSLAAAERAGLETVVCAATPAQAGAVAALGPDAVAIEPPALIGTDTPVSQADPGVVTEAAAAVETAAPGTPVYCGAGISTGADVRAAYELGADGVVLASGVTEATDPQATLAQLVAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYH3</accession>
    <name>U1MYH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01375</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89220">
        <property type="protein sequence ID" value="ERG89220"/>
        <property type="gene ID" value="J07HX5_01375"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016294_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="2">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="493" mass="53150" checksum="ADC9444DFCAF5E86" modified="2013-11-13" version="1">MAETEQVAVAEVSDGFGSVGDPGAAVSLPVVELLTGRGFATGKSGAGKSNSISVIAEKLLDNGFGLLIVDIDGEYYGLKEAYELLHVGADEECDIQVTAEHADKLATLALERNVPIILDVSSYLDESEAEAVLTAVAQHLFAKAKKQKQPFLLIVEEIHEYIPEQGSVGEAGKMLIKIGKRGRKHGLGIVGISQRPADVKKDYITQCDWLLWHRLTWDNDTNVVRRMLDGEHASAVEELADGEGFLMTDWAETERVQFYRKQTFDAGATPGLDDFERPELKSVSDELVAELDGASENNDTDESDRIADLRTTLEEKNSRIAELERELKDAQDLRRMAAEFVDALVQHVEGAAPGRTGQERMQTRLRSSNEPERADDDADTAGPAPAAGGESSDGRTERSNGHGSAFSAAAIFETLSAASDLSIDAVERHDESSLRDRLAAGQTETETETEADHVADDGANTQDAPDGLNPASANQEPVASXXXXXXXDGQLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYK5</accession>
    <name>U1MYK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01260</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89108">
        <property type="protein sequence ID" value="ERG89108"/>
        <property type="gene ID" value="J07HX5_01260"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101661_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040493">
        <property type="entry name" value="DUF5518"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17647">
        <property type="entry name" value="DUF5518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="183" mass="18414" checksum="FB2286B0B825D935" modified="2013-11-13" version="1" fragment="single">MSADKRTTERSTSASAGGQSGSKLPAAVEWVLGILVALGGALALRIGTALGAAVDRETIADGIENGNIVIENDLGGGEELTAAEGAKLIDTLVSWVEIGFLVVGVGMIVAAVGYLYIRRQAREGERPGQQSAAVGTHVLLGAVIGAVLSFIPLATGLGGAVAGYFEQSSSRNPTRAGAISGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYP2</accession>
    <name>U1MYP2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L18e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl18e</name>
        <name evidence="4" type="ORF">J07HX5_01448</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89290">
        <property type="protein sequence ID" value="ERG89290"/>
        <property type="gene ID" value="J07HX5_01448"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146465_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00329">
        <property type="entry name" value="Ribosomal_L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_L18/L18-A/B/e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022947">
        <property type="entry name" value="Ribosomal_L18e_arc"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12450" checksum="48133E9586B2FF50" modified="2013-11-13" version="1">MSKTNPRLASLIAELKSVTRAGGGDVWNDVADRLEKPRSTHAEVNLGRIDRYARPGETVVVPGKVLGSGVLRTEVTVAAVDFSGTAEIKINQVGESLRLEQALEDNPDGADTRVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYU9</accession>
    <name>U1MYU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Ser protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01503</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89345">
        <property type="protein sequence ID" value="ERG89345"/>
        <property type="gene ID" value="J07HX5_01503"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_361184_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="761" mass="86563" checksum="0623F8328BFF9104" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ43</accession>
    <name>U1MZ43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01471</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89313">
        <property type="protein sequence ID" value="ERG89313"/>
        <property type="gene ID" value="J07HX5_01471"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="344" mass="37599" checksum="C5EC196C958D7D22" modified="2013-11-13" version="1">MSRQQAVEQAIDRRRQQINDAVEVDLPMAEPARLYEASRYLLKAGGKRLRPTVLLLVAEALADVKPLSTDYRSFPAADGQAVDVMAAAVSVEIIQSFTLIHDDIMDSDTVRRGVPAVHRKYDRSTAILAGDTLYSKAFEKMLQTGAEAGRSVEALSELATTCTEICEGQSLDIAFEQRAAVTPDEYLEMVKLKTAVLYAAAASIPAVILGYDDAVEPLHSYGLDIGRAFQIQDDLLDLLTPTETLGKQRGSDLVEGKQTLVTVHAKTNGIDIDGLIETDSIEAVTETEIEQAVAELERAGSIEYARTTASELIESGKTHLRTLPENAARARLSEIADYLIEREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ47</accession>
    <name>U1MZ47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Archaeal peptidase A24 related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01476</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89318">
        <property type="protein sequence ID" value="ERG89318"/>
        <property type="gene ID" value="J07HX5_01476"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065732_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009655">
        <property type="entry name" value="Preflagellin_peptidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06847">
        <property type="entry name" value="Arc_PepC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="14"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Arc_PepC_II" evidence="4">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="35509" checksum="6E0E0E390AEBA82C" modified="2013-11-13" version="1">MAEIASGPDIVRLVVLPYFGYLAWRDYRTRRVPNRLWLPLAGLGIVLFVWELSMVIDGPSLDRQRFLSRVAVSLGVVLPTGYLFARLGGFGGADAKAFYLIALLFPTVPEYNVGAIETVPVVEATSGVFSLTILTNAVLAGGIYPAVLAVQNAMRGHVGPAMFVATPIQWDKAPQRHGSLFRLSGQEPTDDHRLTGFGVSLGQRRVDLDAVRMYLKWRGVSLAELRSAPKQYRDPASLPAEPAEPGDGSVATDGGADDDPWGAEVFLASIDGSAYGTTPEQLRDGLETLTAEDVVWLSPGIPFLVPVFAGLVLSVTCGDLLFGLLTVLVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ51</accession>
    <name>U1MZ51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01619</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89460">
        <property type="protein sequence ID" value="ERG89460"/>
        <property type="gene ID" value="J07HX5_01619"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1087718_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="104"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="27440" checksum="4D36E600A38C356D" modified="2013-11-13" version="1" fragment="single">MPKDSTRRRFLTAAGTGTMAAIAGCLGGGDSDPDDSGPGNTDDTGGESGSTDNTDEQASGGTLQMMATGAIQTLDPINAKGSGAGYNQYNQQLLYFPDGQKPPEAALAQEYEISEDGLTYTFTLREDATFHDGSSVTAQDVVYSFRRLAESDNSRNRDDIVGDTLVLEHEKDATLSEPTDEETLADVVPESLGIEAVDESTVEMRLRQPFEFTLYQIAGGAFSILPENAVGDIEGYDGQFEYNEFFSTQGSGPTYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ97</accession>
    <name>U1MZ97_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
            <shortName evidence="6">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">serS</name>
        <name evidence="9" type="ORF">J07HX5_01690</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89525">
        <property type="protein sequence ID" value="ERG89525"/>
        <property type="gene ID" value="J07HX5_01690"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_0_1_2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="142"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="6">
        <location>
            <begin position="241"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="71"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="272"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="368"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="459" mass="51077" checksum="D813BC9DBD9E8191" modified="2013-11-13" version="1">MHAQQQFVRENPDAVREGLALRGTSFDLDGLLEIDQQWREHKSHGDDLRQERNEISDRIGGLKRAGDEEAAQAAIERSRELKTELETVEAEADELKAELDARLLELPNVPQDVVPPGEDEQDNKEVRRVGVADVTLPANVVPHYELGEQLGILDFERGAKVAGGGFYFLRGDGARLEHALIQFMRDCHRDHGYTELFPPIPVSTRSMTGTGQLPKFADDAYRVGGHNDESYDEDDLWLCPTAEVPVTNMYRDEILLDEDLPIKHQAYTPNFRREAGEHGTETRGLGRLHQFNKVELVNFVAPDRSDERLEGLVGEAETVLEKLGLPYRVVLLCGGDMTFSAAKTYDIEVWAPADDMGHGPDRGGRWLEVSSASNFEAFQARRAGLRYRPEQHESAEYLHTLNASGTALPRLMIALLEHYQNEDGTVTVPAALRPYMNGQELIAGHEPVGQAAVGAGQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZE4</accession>
    <name>U1MZE4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate mutase epsilon subunit</fullName>
            <ecNumber evidence="4">5.4.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glutamate mutase E chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glutamate mutase large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Methylaspartate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glmE</name>
        <name evidence="5" type="ORF">J07HX5_01746</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2S,3S)-3-methyl-L-aspartate = L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12857"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58724"/>
            <dbReference type="EC" id="5.4.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methylaspartate mutase GlmE subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.1" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89580">
        <property type="protein sequence ID" value="ERG89580"/>
        <property type="gene ID" value="J07HX5_01746"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029922_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00561">
        <property type="reaction ID" value="UER00617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050097">
        <property type="term" value="F:methylaspartate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019670">
        <property type="term" value="P:anaerobic glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019553">
        <property type="term" value="P:glutamate catabolic process via L-citramalate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00245">
        <property type="entry name" value="Glm_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.970.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01923">
        <property type="entry name" value="Me_Asp_mutase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006396">
        <property type="entry name" value="Glu_mut_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014714">
        <property type="entry name" value="Glu_mut_E_C_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06368">
        <property type="entry name" value="Met_asp_mut_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001495">
        <property type="entry name" value="Met_asp_mut_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01503">
        <property type="entry name" value="MthylAspMut_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="3 4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="L-glutamate binding" evidence="4">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="476" mass="51431" checksum="3C9E039A755D5727" modified="2013-11-13" version="1">MITDTRITDAELEQRNRRVWDRYPGDDPATFEDAVAFHESLPKHKQFATVLESASGVLTQPRAGVPCLDDQIELLQTLTDEGDADLLPTTIDSYTRDNQYEKAQVGLKESRTTGKDELNGFPAVNHSVAGCRDLIAAVDAPVQVRHGTPDARLLAAVTLAGGFQSFEGGPITYNLPYTSKYELAETIEYWQYVDRLSGAYTERGVRINREPFGPLTGTLVPPSVAIAICIIEGLLAATQGVRSVTLGYGQVGNLVQDVAAIRAMRQLGAEFLPADVTVTTVFHQWMGGFPRDEPRAQGVIALGSATAAVVEPDKIITKSPQEASGVPTADANAAGLRTTDQVLQMLSEQTIDLEGVDREQELIEQSVRSLLGAVHDVGDGDVACGTIRAFEQGLLDVPFPPSEAADGDVLPVRDDDGRVRLLKFGNLAVDDEVKEIHRARLEDRAATEDRSPSFRMVADDVSAISNGRLVGRPGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZK2</accession>
    <name>U1MZK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01805</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89635">
        <property type="protein sequence ID" value="ERG89635"/>
        <property type="gene ID" value="J07HX5_01805"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070010_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="26346" checksum="F64FB1010912F7C0" modified="2013-11-13" version="1">MTVHHDGVVIDWLGYATVRLATDTTTVYLDPGRYGVLTGAWTPDDEATADTHPPARDYRDDADAVFVTHVHHYDPDGIDRVAAADATVIACEAIAPRDSGRELPRLAELSRPVRTVSHEDEGVATVPFWTVPAYNELEGSHTRADGTPYHPEGLGCGFLISIDGVRVFWPGDTDVLAGHAELDVDVLLPPIGGTFTMDRTAAAALAAAIGPELVVPIHYDTFAALETDARAFAADVEARGVPVALDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZP3</accession>
    <name>U1MZP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01852</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89680">
        <property type="protein sequence ID" value="ERG89680"/>
        <property type="gene ID" value="J07HX5_01852"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072493_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28067" checksum="EB80749C8661FC4F" modified="2013-11-13" version="1">MNPLADLGLSGYEEQAYRALLTTGAASARTVAERSGVPDGRIYDVLNGLVARGLVSTQAGDPRQYTPVEPTAAIDQLLSERVAEIEAAEARYRQLAAQARSTLAPTPPVDAGVWLADLGDEDATVLAGEQISATDERFVMAVGPPYVGAPQNQYRSEITAFIESVPTEITVDLLLDHTIVDDLSTELETLRQVGADITIRHTPQVTVTFDVVDSEAAYIDVPQPFGSGQRFGFLEVRDSLVAARLERGFDAVWQTATPVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZS1</accession>
    <name>U1MZS1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0145 protein J07HX5_01882</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01882</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89710">
        <property type="protein sequence ID" value="ERG89710"/>
        <property type="gene ID" value="J07HX5_01882"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117144_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="12605" checksum="553EC4E4EAE011FF" modified="2013-11-13" version="1">MGLFFIILVITVVMHIVTTETVPGHETDEAIGVARGNTVKARNVGRDITQSIRNLTGGELKAYSELLSDARDEALERMIEDAESLDADAVVNVRMESSEIANGGSEVIAYGTAVRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZY4</accession>
    <name>U1MZY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01793</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89623">
        <property type="protein sequence ID" value="ERG89623"/>
        <property type="gene ID" value="J07HX5_01793"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054164_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021552">
        <property type="entry name" value="ArsP_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11449">
        <property type="entry name" value="ArsP_2"/>
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="355" mass="35363" checksum="DAEAFD2739F88AC9" modified="2013-11-13" version="1">MIPGGVLAEVLTEAWIRIGAFVIASVLVVQFIGRYTASRVVGVLGDRPRVQVLGGGLLGLVPGCGGAIAVTSLYADGRVGFGVLVAALAATAGDSAFVLLVVDARLAVIAYGVACAVGVGLGVAIETHGVWVDRIDGAVRQAGGRRQLRSDGGSPAARRDRSDAHAGVMIVWWSAAAVSLVAGMWGLFVGDLPEAGTGEKLLLVVAVAGIAASAVLVVRSGPTEPETPLGRYTARTVAPIVLWIAVAVGGFELLMSAVSVDPAGIAELVGPFAPIGAGVFGAIPGCGPHIGLVTAHAELGLPASVLIADAVNQDGDALFSLLAADPAAAVVATIYTTVAAVATGVGVYATVGLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0R0</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_02071</name>
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    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89898.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89898">
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    </dbReference>
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        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="11696" checksum="F301C5E458CBEFE6" modified="2013-11-13" version="1" fragment="single">MSKPLSFDMIRYFIFVEDDDTTEEFDSFEAVSDEVRLGILKAFVEERRRRTEIDWTDRKITDDVVILSFSELQDAVGVDDSGRFNYHLDKLVDRFIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0T7</accession>
    <name>U1N0T7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyketide cyclase / dehydrase and lipid transport</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_02101</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89928">
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        <property type="gene ID" value="J07HX5_02101"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="130" mass="14542" checksum="8EAED147A6C69D9A" modified="2013-11-13" version="1">MREVEVSQFVQTYPRRVAGTLSPDTVLEAEGSFSIRDIAADGDRITVGGYGVELVFEFATRENGIEYDQVEGPLETLRTTLTYENENEGTRLTARSEVAAPGPGFIDRLAAWKRRGELRRALRGIADEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P354</accession>
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    <protein>
        <submittedName>
            <fullName evidence="4">Orc1/cdc6 family replication initiation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00053</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87912">
        <property type="protein sequence ID" value="ERG87912"/>
        <property type="gene ID" value="J07HX5_00053"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025112_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0006260">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc6_C" evidence="3">
        <location>
            <begin position="119"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="213" mass="23847" checksum="22C1F52733F8DE3F" modified="2013-11-13" version="1">MIPLPSPXXXXXXXCEREIHFPPYDATDLQTILHRRSELAFRSETLNDEVIPLCAAFAAQDRGSARQALDLLFEAGDLARRAGVEHVTESDVREAQERLQERQIEQSLLDLTTHGHLTLFAVALLADENETPVRKGAVYTRYKSAVDYLDHNPLSDRSVHSHLNELTMLGILNRQEFNEGRAGGVYYEYELAVNLNTVQSALSGVRALDGIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3A3</accession>
    <name>U1P3A3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00113</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87972">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="519" mass="55758" checksum="BAB0ACA515554482" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3E7</accession>
    <name>U1P3E7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00163</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88022">
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        <property type="gene ID" value="J07HX5_00163"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1682623_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="156" mass="17262" checksum="DF2F8882D4E41DB7" modified="2013-11-13" version="1">MAQHLDRLTPTGGRTDNVPDTDTQPTNEDEAVSDETVAADIEDAMSDSTLTWGGVEQQSNTERLNLEMPDTDADVESVDTASATETRSASDDVNNAVDNLRRLQGGEQETTRVESSDDQVDALTQFREEQTDDEEIETGVDTKNGLLNRLRERIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3G1</accession>
    <name>U1P3G1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Archaeal flagellin N-terminal-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00178</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88037">
        <property type="protein sequence ID" value="ERG88037"/>
        <property type="gene ID" value="J07HX5_00178"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243730_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Pilin_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="10896" checksum="E98AD29710437454" modified="2013-11-13" version="1">MDNTRVDPTMSADSRAVSPVIGVILMIAITVILSAVVGTFVLGMTDTVEQDVTAGVTVAQTDNTTTVTWTARGRATSISVGGVAIDGTADDXXXXXXXFRLSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3I4</accession>
    <name>U1P3I4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HoxA-like transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00203</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88062">
        <property type="protein sequence ID" value="ERG88062"/>
        <property type="gene ID" value="J07HX5_00203"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114810_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="22068" checksum="5E388AB7B57067B2" modified="2013-11-13" version="1">MASRPTVLVVDDERDAADVYALRLQEEYDTEVAYSGEAALGAVRADTDVVLLDRRMPEMSGGEVLRTLRERSFEGSVIMLTAVDPGLEVVDMPFDEYITKPAEKEKLVAAINRQVELDRGEARAQYHEVRSKLSVLERELPPDQLNSKTLSRLRERANTLKQQLSDASVADADPDFRSESDIAAPTTSLTSRRPTGNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3P1</accession>
    <name>U1P3P1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uridine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00265</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88122">
        <property type="protein sequence ID" value="ERG88122"/>
        <property type="gene ID" value="J07HX5_00265"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068457_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="4">
        <location>
            <begin position="16"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="25307" checksum="FFE0AA961BA21763" modified="2013-11-13" version="1">MAKQPHLLVEPGELADVALVPGDPGRVDRIAQQCSTAETVAENREYKIVNATYEGREVTICSTGIGAPSAAIAAEELHAVGVERLIRVGTCGALQPGIEIGDMIVATGAAKDEGTTKRYEAATIPAVPGYAVLSALVDTATDRDEPVHVGPVATDDAFYTETESIVERWEAAGLLAVEMETAALFTIARRHDMGAGAICTVDGNLVAGTQKGETDDEELPAKARDNIERAITIALEATRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5A6</accession>
    <name>U1P5A6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00873</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88727">
        <property type="protein sequence ID" value="ERG88727"/>
        <property type="gene ID" value="J07HX5_00873"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1345625_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="204" mass="22436" checksum="150D4A346D108654" modified="2013-11-13" version="1" fragment="single">MVDLIGQAANVVRNLRYRQGAAVRELAARVVYSVRSTTTAAPVLEADWDVLVVLDACRADLFKTAVADGAHDTLPGATEVEARISPASATDEWLEQVFGEARDERLAELAYVTGNPFSSELDHDRFAAVEEVWRGAWDDDRGTIPPQPVTDRAIATWRTGTADRLVVHYMQPHFPSLAAPANDGVRLDDFGTRSLSVWDDLRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5W7</accession>
    <name>U1P5W7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal-transducing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01068</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88922">
        <property type="protein sequence ID" value="ERG88922"/>
        <property type="gene ID" value="J07HX5_01068"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2044331_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS_4" evidence="1">
        <location>
            <begin position="2"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="12734" checksum="9C00E568D55E2D37" modified="2013-11-13" version="1">MPAAVIRIDSDRTVGFASEQAESVFGIAPGDNISQCVTEADWKCVGADTAPESRAKLPFRRVFETSEPVEDVRCVMTGVDGNRLTVGINAAPVYDDGAVDSVVCAITDITGDIQQVQTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P650</accession>
    <name>U1P650_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbamoylphosphate synthase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01177</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89027.1"/>
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        <property type="gene ID" value="J07HX5_01177"/>
    </dbReference>
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        <property type="reaction ID" value="UER00171"/>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:arginine biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
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        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="131"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="530" mass="56890" checksum="65A52ABB8C65A7CA" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P697</accession>
    <name>U1P697_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01234</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89082">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="7181" checksum="1619FD26E8DC71CD" modified="2013-11-13" version="1">MINLSVEWRDREKIAHVGFTPGVNTGILSLLQIADRGDDHADADDEKPDLDPRDQRVDELGPLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6A4</accession>
    <name>U1P6A4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">V-type ATP synthase subunit F</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">V-ATPase subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpF</name>
        <name evidence="7" type="ORF">J07HX5_01244</name>
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    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
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        <text evidence="2 6">Belongs to the V-ATPase F subunit family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01990">
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    </dbReference>
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        <property type="entry name" value="SSF159468"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11783" checksum="F7044FCFB5A0D84B" modified="2013-11-13" version="1">MTREIAVIGNPEFTTGFRLAGVREFAEVPDDQKPTELDAAVEETMADDDIGIVVMYEEDLDYLSREVRQEVERSVEPVVVTLGGGAGSGNLRDQIKRAIGIDLLEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6I9</accession>
    <name>U1P6I9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01340</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89187">
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        <property type="gene ID" value="J07HX5_01340"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8609" checksum="AB56828F7AE2A157" modified="2013-11-13" version="1">MLATLLTLFKREKNRATSVVAECPIGRSGTLRTARGGKGEPPAESGAAVVTSDTGPDAETGSPELNKRGPERPERGRLGEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P718</accession>
    <name>U1P718_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00047</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00047"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243729_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11696" checksum="2A6396C7BF789AD7" modified="2013-11-13" version="1">MSKTTSTVEHELPPLDPECAAVLDKIPEGYSLDSMLNFDNLPASRKRIRDAMEMMTDNEEILETVHTKEISIPSPGDAEQLXXXXXXXSRVLMPAQPTPDERHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P738</accession>
    <name>U1P738_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proton_antipo_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00077</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87936">
        <property type="protein sequence ID" value="ERG87936"/>
        <property type="gene ID" value="J07HX5_00077"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1368721_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="6">
        <location>
            <begin position="57"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="21282" checksum="248263FFB0FAF84E" modified="2013-11-13" version="1" fragment="single">MSDSSSQTVGQLPSSDGNSSRFPAILTRLAWGLWLLSLAAVTGRLWAGEPWRLGEVFVVDGLTVVLWTTVTFFSGIVHSYARRYLSGTDGRRRFFRRVFAFTLVVMVLVAANALVVFVGAWLVMGLVMARLIGHADFPQATAAAQVSRRYFLASAGLLGGTLGVLWWHTGATTVTGVAKTVGALPSPVVLVAATGLVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P743</accession>
    <name>U1P743_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00082</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87941">
        <property type="protein sequence ID" value="ERG87941"/>
        <property type="gene ID" value="J07HX5_00082"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="16"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="366" mass="38920" checksum="537D8FA3137F2460" modified="2013-11-13" version="1">MFDLATEVERNGMDPVRLEVGEPDFDTPEHATEAGFEAARGGATDYTESVGIRPLREAIADRLGEYGLTHTPDEIVVTTGGMEALHVTDLAVVDPGEEVIVPTPAWPNYAIHAALAGGSVRAVPTPPPYDLDADRVIGAMGPDTAAVMLTTPSNPTGRVYDEQPIQRVVAAAADHDAYVIADEVYAGLTFDREPRGVAAITGMPDHVITIGSLSKTHAMTGWRLGWLAAAPAIVEKTTAVREATTSCPAAPAQHAAHAALTGPRGPEQAMYDAFRRRRSYVVDRLAEIDGVSAPRPEGAFYAFVDVDGADDGLELAKYLLREGGVALAPGTAFAERTTGRVRLSFANSMDRLEEGLNRLEQALPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7A4</accession>
    <name>U1P7A4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00157</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88016">
        <property type="protein sequence ID" value="ERG88016"/>
        <property type="gene ID" value="J07HX5_00157"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353113_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="9947" checksum="248B0EEA725E6160" modified="2013-11-13" version="1">MRDLSHKPTVSYRDQYTLGGLLVYAAVVPAVITVLSAPQLAVAFVGGVFTALLLNRLRGRAGGTALGSDTDTDPGTRSDPRTSADTGADSAQTAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7C5</accession>
    <name>U1P7C5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lycopene cyclase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00182</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88041">
        <property type="protein sequence ID" value="ERG88041"/>
        <property type="gene ID" value="J07HX5_00182"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076391_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045436">
        <property type="term" value="F:lycopene beta cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016120">
        <property type="term" value="P:carotene biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017825">
        <property type="entry name" value="Lycopene_cyclase_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03462">
        <property type="entry name" value="CarR_dom_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="287" mass="31758" checksum="A04AB5DA6BC79394" modified="2013-11-13" version="1">MELTYLQFHLVFVLPVVLGLLYLCPQSPPVRRRRGAVGIGILVTIAFAYTTPWGSYMIQQGAWWYGDGFAAVVGRQLQVPLGEYLFFVLQTVIVGLYLYVRGFDPTFREGDFALLPRVAGVAAGLGLLGGGLYLVMLGDSYLYLGGLIAWVGPVFALQWAVGGGYLTRQVRPWVEAAVVPSMYFWVADRTAIEIGXXXXXXXDRTAIQVGTWVISKQHTTGVAVLGLPIEEMLFFVSASLMTVYGLVLFEWVLDYNDQTGTLDQYVPAMIMQRLTPKRVDDRQTSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7G8</accession>
    <name>U1P7G8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">PGF-CTERM archaeal protein-sorting signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01667</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89502">
        <property type="protein sequence ID" value="ERG89502"/>
        <property type="gene ID" value="J07HX5_01667"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027187_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
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        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="519"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="534"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="581" mass="63629" checksum="9140C8AEE4F58E8B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7R2</accession>
    <name>U1P7R2_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Putative nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module</fullName>
        </submittedName>
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        <name evidence="5" type="ORF">J07HX5_01763</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NOB1"/>
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    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_6" evidence="4">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="17139" checksum="D9DFC848EABB414C" modified="2013-11-13" version="1">MYVLDSSAFINEFHTDDDIATIPMVREELEDESAYRFDALEGSGMYLHIPDGETVERIERAARETGDLGELSRTDVRLVAAAFELDGQLTTDDYAMQNVADRVSVTVEVIDRDGIDEQRSWQFQCQGCGREFDDHHDRCPICGSSLSRKNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7T9</accession>
    <name>U1P7T9_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Lignostilbene-alpha,beta-dioxygenase related enzyme</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">J07HX5_00354</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
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            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ERG88211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
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        <property type="entry name" value="PTHR10543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11327" checksum="6B04A4D36C5C90D6" modified="2013-11-13" version="1">MSLAQPATEWATGVLKYDTETGDVAEFDRGGEYFGEPVFVPGPGDREDAGVVLTVGLDVDDGRSRLLVLDGESFEERARVTLPHAAPFDFHGRYFPELRAEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7U0</accession>
    <name>U1P7U0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01797</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89627">
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        <property type="gene ID" value="J07HX5_01797"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1010499_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ArsP_2"/>
    </dbReference>
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        <property type="entry name" value="ArsP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="275" mass="27420" checksum="FBC69C80592D2B79" modified="2013-11-13" version="1">MAVCPEQLGHAVAILGVGAXXXXXXXRLAVLAYGVTSAVGVGLGVAIETHGVWVDRIDGAIRQASGRRRLLSDGGFPAVRRDRSRAHAGVVLVWWSAAAVSLAAGTWGLFGGGLPESSTGATALLAVAVTGIAASAVLAVRSGPAEPETPLGRHTARTVAPILLWIAVAVGGFELLMSTVSVDPAGIAAFAGPLAPIGAGVFGAIPGCGPHIGLITAHAELGLPVSVLIADIGNQDGDALFSRLAANPSAAVVATIYTTVAAIITSVYATIGLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8D9</accession>
    <name>U1P8D9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00520</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88376">
        <property type="protein sequence ID" value="ERG88376"/>
        <property type="gene ID" value="J07HX5_00520"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2010027_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="13210" checksum="4728E48B37D535F2" modified="2013-11-13" version="1">MIVVVIVVLVLIFVGLVTLVFIVVFVLILVGLVFLGLDFEHLASVAVNLDLADAAVSRVDEHLIDRATLVLKLDILGGSVDAVGCNINCLILDQLCVGRVRAGDERDCAGTTDEQEDSYRSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P923</accession>
    <name>U1P923_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="2">DHNA-CoA synthase</shortName>
            <ecNumber evidence="2">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">menB</name>
        <name evidence="3" type="ORF">J07HX5_00782</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88636">
        <property type="protein sequence ID" value="ERG88636"/>
        <property type="gene ID" value="J07HX5_00782"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_7_2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="90"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="2">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="2">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="32226" checksum="A0F93C0C41CBB34B" modified="2013-11-13" version="1">MTVTSELFAPSQWDRVSEFSFTDITYHRAVDTGAVRIAFDRPAVRNAFRPETVDELSRALEHAKRQSSVGAVLLTGNGPAPDDGGWAFCAGGDQSVRGADGYEYDANETDVGRLHILEVQRQIRHLPKPVIAVVPGWAVGGGHSLHVVCDLTIASAEHARFLQTDPDVASFDGGFGSVSLARQVGQKKAREIFFLGKRYDADEAAEMGLVNAAVPHAELEQRALEWADRITDKSPTAIRMLKYAFNLPEDGLVGQQVFAGEATRLAYMTDEAAEGRDAFVEGRDPAFDQFPWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9D7</accession>
    <name>U1P9D7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00897</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88751">
        <property type="protein sequence ID" value="ERG88751"/>
        <property type="gene ID" value="J07HX5_00897"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3110639_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043953">
        <property type="entry name" value="DUF5784"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19096">
        <property type="entry name" value="DUF5784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="5372" checksum="E2A8F1C0298BAC25" modified="2013-11-13" version="1" fragment="single">RDDEWATITGASPSIGHEPAVVYRYRPDGSVTGYTRGQPGPGLGLQSVLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9U6</accession>
    <name>U1P9U6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01007</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88861">
        <property type="protein sequence ID" value="ERG88861"/>
        <property type="gene ID" value="J07HX5_01007"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3385902_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="32" mass="3324" checksum="52450A1B4D0B7974" modified="2013-11-13" version="1" fragment="single">TAAEAESLLTNAGFETPIVAERAETFLLVGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9V7</accession>
    <name>U1P9V7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01017</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88871">
        <property type="protein sequence ID" value="ERG88871"/>
        <property type="gene ID" value="J07HX5_01017"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_770758_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="363" mass="39057" checksum="21E9F81A89014842" modified="2013-11-13" version="1">MPDDDIPSSRRTALSRRALLATTAGAVTLSAGHAAATTPTDQMADDPSDSDRPAAVAQAYIEALDADDRGSANELIAADGILSAWSEQEFDWVGGFEITYVGFETVAQRDGDVTADITLTIAGNTGTVRYRFRDTTDGWLIWEALDGLRSAPAQETDTETTASAAAEAYVTALNAGNRGAVNELIADDGALSAWSSQEFEWVGAFEFEFGGFQTVRTNGNEIVGDVELTIAGNEQTLRYRFREVAPGRVELSAPVAGLRTTGEPSAEAAADAYLTALETADRDRTNKLIADTGQLAPWSGQEFEWVRAFEFELVGFEATEQQNDSVVADLTVRIADTTAAVSYEFRRIDAVGWKLWDAPDGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAF5</accession>
    <name>U1PAF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01233</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89081">
        <property type="protein sequence ID" value="ERG89081"/>
        <property type="gene ID" value="J07HX5_01233"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2127741_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040493">
        <property type="entry name" value="DUF5518"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17647">
        <property type="entry name" value="DUF5518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="10771" checksum="DB3BFB2E35A3C14D" modified="2013-11-13" version="1">MLSFIPSATGLGAVAGCSLATGSGGAVAGYFEQSSSGDSTRVGAVSGVLVVVPVLVLLVFVLAELISGLQAVGQGDAAGISVVVVLLVGAVSVAFTTGFGALGGFVGGWIAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAZ3</accession>
    <name>U1PAZ3_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01418</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89261">
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        <property type="gene ID" value="J07HX5_01418"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176022_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="7789" checksum="222D41BF4F37ABA3" modified="2013-11-13" version="1">MEQNMGVTDERLRVGLGAVLGGLSLGILANAVGLPTVLSPLLGLIGVMMLVTGTIGTCPMYSLLGVDTCSVDANTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBD4</accession>
    <name>U1PBD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01529</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89371">
        <property type="protein sequence ID" value="ERG89371"/>
        <property type="gene ID" value="J07HX5_01529"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754626_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="16240" checksum="3F00B60D4B04A7A8" modified="2013-11-13" version="1">MCSHRRVNANRVRSFAPANLLGHRTETAAPRVRALRAFRVCSRVYIIAHSTLDYATRPLVRESPGLCPLSLRVATTRQTDVPESTWVSLDPVRSSGDGTLTGDGRSVPSTATPAPIAQLWVPDPSYVGERVSYQLLLTYCVTIYSPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBP5</accession>
    <name>U1PBP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01661</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89496">
        <property type="protein sequence ID" value="ERG89496"/>
        <property type="gene ID" value="J07HX5_01661"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1063991_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="225" mass="23305" checksum="6B8DE386D99F422E" modified="2013-11-13" version="1">MPNEKLLALVLAFAAVGGLVATGAFTSVEAERTADVSVGGDQDALLGLDPIDRSSFVQNADTSSDTFEIDLADDQLNTNGTTNAGPVVSVTNNGQNTVQLVVNVSGGIISSDDVDVAFYTNDSGVSTGDTDPISVDTVIDEYNAFFDSTDYLISSTQNSDPTNVADSRVIELDSGESFDAHLAIQIDDPDGSIELSGTTLFDTVTFLATSNGELTSDSPGLTVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBY5</accession>
    <name>U1PBY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01762</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89596">
        <property type="protein sequence ID" value="ERG89596"/>
        <property type="gene ID" value="J07HX5_01762"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2579198_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="80" mass="8570" checksum="43DD21EBB980D72D" modified="2013-11-13" version="1" fragment="single">AAAGRPTVRVEIDRLDPVSVGRLLYTMEAACVLAGELAGVKTFTQPAVEWGKRAARGLLDEPNTTPEAAAVSDKTQYRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC04</accession>
    <name>U1PC04_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mut7-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01786</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89616">
        <property type="protein sequence ID" value="ERG89616"/>
        <property type="gene ID" value="J07HX5_01786"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112469_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002782">
        <property type="entry name" value="Mut7-C_RNAse_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01927">
        <property type="entry name" value="Mut7-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mut7-C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15518" checksum="4874146F20CE4E99" modified="2013-11-13" version="1">MRLLLDAMLGGLRSYLRMCGHDTAYALEAGVAADADLLALADAEDRRLITRDQALGARAPDAVVLTARETTAQLAALADAGIELSLSATPTRCSVCNGTLEPVPATAATPPAVPDPAGTDVWTCRGCDQRFWKGSHWERVAATLAAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC52</accession>
    <name>U1PC52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01842</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89671">
        <property type="protein sequence ID" value="ERG89671"/>
        <property type="gene ID" value="J07HX5_01842"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1801633_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15025" checksum="2D0291FD2C7AE1B0" modified="2013-11-13" version="1">MLNAYYRLEGYRPKSAGRYESLGSAAATTPTCPASPFPVLFWSGLAYTGVTAEAAQKVTGLGVGRQRQRTLASVLALSCLARLQRATLVPERPRSGVLALPTEDVAVEVVLVFPELVDNPGGVVRANAAGGECDDSLFSVALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC67</accession>
    <name>U1PC67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01858</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89686">
        <property type="protein sequence ID" value="ERG89686"/>
        <property type="gene ID" value="J07HX5_01858"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3192611_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="47" mass="5154" checksum="0825C9EC6564AE27" modified="2013-11-13" version="1" fragment="single">MLGLLQLLVVLSTRSESCPEAETDTGPVLARRGLVFSPRVDARWLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCN5</accession>
    <name>U1PCN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02018</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89846">
        <property type="protein sequence ID" value="ERG89846"/>
        <property type="gene ID" value="J07HX5_02018"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2299241_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="10740" checksum="2F6DFCD69118BB02" modified="2013-11-13" version="1">MTELDSEQTEQPEQTASAHAESGDPEITNYLYAGAVVILSLAAVFAAAGLYSSVMSIIDIWIAAEFKPIFRLLLHLSVLLFTIMGISAAVRRMGTPLVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCW9</accession>
    <name>U1PCW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative GTPases (G3E family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_02109</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89936">
        <property type="protein sequence ID" value="ERG89936"/>
        <property type="gene ID" value="J07HX5_02109"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="3">
        <location>
            <begin position="10"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="4">
        <location>
            <begin position="292"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="395" mass="43029" checksum="281CB01F1023952E" modified="2013-11-13" version="1">MSLLGTDGTPVTVLSGALGAGKTTTLNHLLANPGDRNIAVLVNDMGALNVDAELIEAQGDGITELSNGCICCDLRDDLEVAVSRLARTGEFDQLVVESSGISAPTPVARLFTTGPASAPYRLDTLTTVVDATSFQETLATSDIVTTEDIRRERPGQAETEGDVRPLSDLLVTQAEHANVVVINKCDRASEETIVETEALLEALNPDARRHRARHGAVEPATILDTGLFSPELLSLGDRREQVLEHAESETALDTKVSGNDPEGGDHSHDHNRGHEHNKHDDHDHDPAETYGITSIAFKSRRPLHPERFAAFLRALPDSVIRSKGLVWVAGRDDLALRYTXXXXXXXRPTGWIRSRRSSTRQASGDARRRRYRHHRGYPPRTAGPGRDRGRHPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PD11</accession>
    <name>U1PD11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L37AE/L43A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_02154</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89981">
        <property type="protein sequence ID" value="ERG89981"/>
        <property type="gene ID" value="J07HX5_02154"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141199_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_L37ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="9551" checksum="12E4CC4C609BC5AB" modified="2013-11-13" version="1">MSNKGSRTASAGRFGARYGRVTRRRVAEIEREMQNATVDGDDVTRLSTGVWVNKETGKKFTGGAYNPETPAGQTATRSIRAALGEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFK3</accession>
    <name>U1MFK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00040</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87899">
        <property type="protein sequence ID" value="ERG87899"/>
        <property type="gene ID" value="J07HX5_00040"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="385" mass="41921" checksum="F632AB46C719A665" modified="2013-11-13" version="1">MRTDVTSDADRGLNPGNRNWERSERPSPLGSILSRPTAAVPVPRGTLIREQSIASCMAKSRLNTDLKFEGIAPEEAFSVLGNEIRLDIVRALWEAGAANQYDDICGAEQTMSFTELRRRVDVRDNGKFNYHVSKLAPHFVRQTEDGYRLSGAGKRIARTVIAVSGEEEVDVSADLDQDCPLCGAAMTVAYEDQWLRIECTECKGLFGDETPEGMVYLANYPSAGLSQRSADEALSTGLFRCMLDQAYLMQGVCRECAGHVSTTLSVCESHDPAAGDPCLNCGTHSQVWADERCETCGFAKRLPIEICSMGLTPVISFLDEQGIDALAPTFDEIVGLLDSRFETAVSHDPLRVTITVDGDAGSLKLVLDETMTVLDIDRPAPTAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGX9</accession>
    <name>U1MGX9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00650</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88504">
        <property type="protein sequence ID" value="ERG88504"/>
        <property type="gene ID" value="J07HX5_00650"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313090_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="209" mass="22854" checksum="47488B39AB619249" modified="2013-11-13" version="1">MTARAVTFTGPREVSVEERSVPEPGPEEVRVNATVSAISPGTELLVYRGDVDRSIAADETLDALDGSLTYPIEYGYATVGDVTATGSAVSGLHGKQVLAFHPHASXXXXXXXGRVVVGSWYGTKPAELSLDSRFHRSRIELVSSQVSTIAPDRRGRWDKDRRLATARNYLRRVETESLITHQLPISEAGRAYELLDGHPEEAVQVLLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHM1</accession>
    <name>U1MHM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00970</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88824">
        <property type="protein sequence ID" value="ERG88824"/>
        <property type="gene ID" value="J07HX5_00970"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112917_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5804" checksum="EC917A311FB6556A" modified="2013-11-13" version="1">MVETPILKIVWYEGEITFLPGDNRRRVPQQSPSLDERDRQTERSSEGSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHP1</accession>
    <name>U1MHP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00990</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88844">
        <property type="protein sequence ID" value="ERG88844"/>
        <property type="gene ID" value="J07HX5_00990"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1398905_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="195" mass="19826" checksum="47D17D5472F1E364" modified="2013-11-13" version="1" fragment="single">MVVILLLAAAVGPAVTATTAHQQTQQTAGGLGGAADEAYVDSDNETAVLAYELGETDVKSLTLEADREAGIATVESTLESADSGAAFDFDELDLAARATQNNLTVVASVDAAKPDIINAFELTLNQTATQEELSSALDLKLGIAGDESERVGLETTPGQPTTTGEITIGPDAATVTADLEAPVTPLLLALTSPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI02</accession>
    <name>U1MI02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01119</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88969">
        <property type="protein sequence ID" value="ERG88969"/>
        <property type="gene ID" value="J07HX5_01119"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="34288" checksum="EED90E71AE5456C0" modified="2013-11-13" version="1">MGEAEQAQSRLAPDDAFSALGNEIRVEILRELGEAGTALAFSELYDRVAVDDSAQFNYHLDRLEGHFVGKSDAGYALRRPGRRIVEAILSGAVTDDPTLERTPTDELCPGCDSHVEIEWHEGSVEVYCPTCTRRWQQSWGRVDGPEQAPQGYQGRLPVPPAGIMDRSPTEIYQTAFTWTSLELMSVASNICPRCAATVTTELNVCETHDATDGPCSSCGTTYAVRLVAACTNCIYSAGCAAAWGVVSTTELLTFLFEHGLNPVAPGAARRLDAVINEYGEQIHSTDPFRAEFSFSIDGDQLTLAVDETLAVVDTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI21</accession>
    <name>U1MI21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxy-3-methylglutaryl CoA synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01144</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88994">
        <property type="protein sequence ID" value="ERG88994"/>
        <property type="gene ID" value="J07HX5_01144"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008065_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG_CoA_synt_N" evidence="2">
        <location>
            <begin position="41"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="HMG_CoA_synt_C" evidence="3">
        <location>
            <begin position="233"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="483" mass="53129" checksum="318980E1E11D40DC" modified="2013-11-13" version="1">MLVIVAYVVTGQDRRSTACSTVDELVVDRHLYTVSVTPNMDIGIDGIELWSGKLRLDLAETLAPATGAAPEKYTKGIGLRASSLPDSYEDIVTMAANAAHRLIERKEITLDEIGRVDVATESAFDRSKPVSTYVAGCLESVHPGSLTHANKGERKFACLSGTQALDDAYNWIRAGRHRDQAALVIATDTALYARDDPGEATQGAGAVAMLVDEDPDLVAFEPPQGIGSVDETDFLKPNQQFPSVDGQRSIQVYLARMREAMVNFARHGGQTHPDKVALVPFHTPFPGMVRKAAPLGYRHAIRDTEYEDRVADAIGRQPRPEGFESDETYLSAVKEYTEALKQTEQYQAWYDRTVAPTLAISRQVGNWYTGSVHVTRVAGLLEASDAGRDLAGSRLLVASYGSGAQAEIHAETIQPGWEAELDALSIRDQLAARREMSFEEYERIHDAHNHAENTDTEPLTTPDAEFVFDGWGRMGEREYTFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIQ8</accession>
    <name>U1MIQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01467</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89309">
        <property type="protein sequence ID" value="ERG89309"/>
        <property type="gene ID" value="J07HX5_01467"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2284942_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="101" mass="10692" checksum="F33A67C4668F0460" modified="2013-11-13" version="1">MELKISTSSLVVREYGTVLLLTATVGGATGVSPGRGGATDLHGRAVCSGVNSSQSVTGEVGENYIRLRVKCSPSMVKPRGLSPRYFTRRVHRPGVFGSQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ86</accession>
    <name>U1MJ86_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holliday junction resolvase Hjc</fullName>
            <shortName evidence="10">Hjc</shortName>
            <ecNumber evidence="10">3.1.21.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hjc</name>
        <name evidence="12" type="ORF">J07HX5_01689</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Holliday junction resolvase Hjc family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="10"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89524">
        <property type="protein sequence ID" value="ERG89524"/>
        <property type="gene ID" value="J07HX5_01689"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139546_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00523">
        <property type="entry name" value="archeal_HJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01490">
        <property type="entry name" value="HJ_Resolv_Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002732">
        <property type="entry name" value="Hjc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014428">
        <property type="entry name" value="Hjc_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39651">
        <property type="entry name" value="PTHR39651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01870">
        <property type="entry name" value="Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="185" mass="20268" checksum="6E03497B4F61ADC8" modified="2013-11-13" version="1">MSNAKGDRRERELVNKLDEAGFAVMRAPASGSATDRELPDVLAGDGDRFYAVEAKSSAGDPIYLDGEEVYALVYFAQNFGAKPRIGVRFDREDWYFFHPDELYQTDGGNYRVKKETAVADGTDFPELTGHSARRTLLDAAQSDGDRDEDGDGEKAHTDGSEGVRRVLAALERGDLSVDEAVGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJB3</accession>
    <name>U1MJB3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Replication factor C large subunit</fullName>
            <shortName evidence="4">RFC large subunit</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Clamp loader large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfcL</name>
        <name evidence="7" type="ORF">J07HX5_01725</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the activator 1 small subunits family. RfcL subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89559">
        <property type="protein sequence ID" value="ERG89559"/>
        <property type="gene ID" value="J07HX5_01725"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027255_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01508">
        <property type="entry name" value="RfcL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023935">
        <property type="entry name" value="Rep_factor-C_lsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="36"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="413"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="449"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="509" mass="55402" checksum="4BA3598000AF5456" modified="2013-11-13" version="1">MTDWTERYRPSSLSELRGNNSARDELREWARDWEPTGDAAVVHGPPGVGKTSAAHALAADMGWETVELNASDSRTKDDIQRLAGRAARNSTLGSSRQLIIVDEADNFHGNVDRGGSRAVTKIIKQAGQPIVLLANEFYEMSNGLRTACREIEFRPVTTRSILPVLRDICRKEDTEFVSAALEAIAETNSGDLRGAINDLQAAAEGRDQIERADVVTGDRDQTEGIFEFLDSVIKEAGPQAALEMSYDVDETPDDLINWIEDNMPKDYADTELVDAYDALAAADQWLGRVRATQNYTFWRYATDNMTAGVAAARDGQKGGWTRYGPPSYWSKLGRSRGTRQTRDAVARQIAQSNGVSVETARRTLLPYLRLITHHCKNRELTVAMAAQYDLDAEHISYVTGSGETTNKVQSIVEEGQTRRDEEAVEQSQGAFTGLGADADADTVTEPTDDDPTPAATSEESPSSGSASGSQTATDNLIDGDTDTNRSADATDDTDVGAEDDQQAGLSDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJI8</accession>
    <name>U1MJI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding ferritin-like protein, oxidative damage protectant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01820</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89649">
        <property type="protein sequence ID" value="ERG89649"/>
        <property type="gene ID" value="J07HX5_01820"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098183_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016722">
        <property type="term" value="F:oxidoreductase activity, acting on metal ions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00818">
        <property type="entry name" value="DPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00819">
        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="31"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20147" checksum="639FA4B17FA42427" modified="2013-11-13" version="1">MSTQKTVLREFGSVEENELRLDTEKATQIVDALNTDLAATYVLYHQLKKHHWNVAGAEFRDLHLFLDEAAENAEDGIDEMAERLQAIGGTPVSGGAAVEAHAPVEPEDEDLYDIRTSLEHDLDLYGEIIESLRDHIELAEKLGDYATGDILKGILVDLEDDAHHIDHYLEADTLVLESATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJV9</accession>
    <name>U1MJV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP:corrinoid adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01961</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89789">
        <property type="protein sequence ID" value="ERG89789"/>
        <property type="gene ID" value="J07HX5_01961"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088595_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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    </dbReference>
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        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="22961" checksum="B465A67040ACC016" modified="2013-11-13" version="1">MTDTPQEVVPPRQITPAAPDEFGLVQVWWGEGKGKTTAAMGMGLRAVGHGYRVHMLQFMKGGAASVEDVRGEYNAIAATPGFSYENRGHYGWHVPGDDEPDHAAQAQAGLERAQELAAAASDAGTTALAPDASPDQGCHMLILDEILYAANRRLIEPEAVVELAATKPAELELVCTGGHQEPTYVLSQADLVSHIEKQHHPIEEGQTARKGTEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK30</accession>
    <name>U1MK30_9EURY</name>
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        <recommendedName>
            <fullName evidence="5">GTP-bdg_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_02046</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89874">
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        <property type="gene ID" value="J07HX5_02046"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1551764_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-bdg_N" evidence="5">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="129"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="172" mass="19155" checksum="0063AC5EE72BA0D4" modified="2013-11-13" version="1">MSQRAVIACRQGEQTTRTPSFRAIVTALGHRIVDEREQQRQEHNRYNLGPGLVDELSQIVDERDCGYVAVDNQLHPGQLSDLTAALAPATVRDCRGVVYERLANGGNRAAANRRDAQQLRGKRRRLLADNRERRQQPRILSVNVSDSTRSSTHSGSDSASRLQTGKQRARGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK35</accession>
    <name>U1MK35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02056</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89884">
        <property type="protein sequence ID" value="ERG89884"/>
        <property type="gene ID" value="J07HX5_02056"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077586_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="275" mass="28743" checksum="2A1C0696F8FE62B1" modified="2013-11-13" version="1">MEALVVGGGTMGRWAGQVLRSTNRIEAVAVTDADPDVAADAAATIDGRVADKTEQFGVVCIAVPMPAVRSAVATHAPRATTAVFDLIGAMAPPIAAMRDHAPDCERFSLHPLFAPAGEPGNVPVVVDAVGPVARALQKTLRARGNHVFKTTAADHDQAMETVQARTHAALLAFVLAAEPVAEQFHTPVSAQFHALAEQLLDGTPRVYADIQATFDGAADVAAVADTIATADRETVHRLYKRARAQTQAQSRAEGTQPAGTTLNTAADDSDTNTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVF0</accession>
    <name>U1MVF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00227</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88085">
        <property type="protein sequence ID" value="ERG88085"/>
        <property type="gene ID" value="J07HX5_00227"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_C" evidence="1">
        <location>
            <begin position="35"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18200" checksum="48055B59A6A12305" modified="2013-11-13" version="1">MSDDTRXXXXXXXVELVRAASEEAPILRASNFSRGIHALARAIGPALEALPEYDVELLETHHSRKRDAPSGTADTLLETVADHREVDRVPGRVGTHQRDDAEVGVLVRRAGTVRGEHELLLAGNDEVLTLTHRAEDRGVFAAGALDAAVWIDDRPPGWYSFEAVIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVH2</accession>
    <name>U1MVH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00104</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87963">
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        <property type="gene ID" value="J07HX5_00104"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2032783_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="13561" checksum="5180A7BAF9F9D330" modified="2013-11-13" version="1">MPRSRTEDGVFGDDERRHLSNQLTPRPLTTAPLADTVQVQTNLIDVGIDTATDHCVDYLMCPDIVSDCWSFISSGEYFCSRVGWCDHPSGEADSRQGTVASPETRQLKKIELECRYQPVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVH8</accession>
    <name>U1MVH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00258</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88115">
        <property type="protein sequence ID" value="ERG88115"/>
        <property type="gene ID" value="J07HX5_00258"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1028982_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002749">
        <property type="entry name" value="DUF63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40700">
        <property type="entry name" value="PTHR40700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01889">
        <property type="entry name" value="DUF63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="287" mass="29685" checksum="6D972FEC29F98B99" modified="2013-11-13" version="1">MPVPFAEFVIPPVGYTVGVLVVTGLVFWGLSRVRPPVTQATVLALAPWMVVGAVLHVLWQLEQSLATPIVPSVAEPLLSAPTVYVATFCLAGPAWLGLSLVQTLPARLTVSRALGLAGLGALGALIGVMGARVQAASLSGVTPGAPLVGLLAAVGVTGVGYGLISRWQLGTVPIDRVRYAGGLVLFAHAFDATTTAIGVELLDVEERSAAPRAIMNVAATLPTEPLLGEAWLFIVVKLFLAVGIVVGFAEYAEESPTWGNLFYALIAAVGLGPAANNFFLFIINTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4622" checksum="00791AA0F060B7A0" modified="2013-11-13" version="1">MNDNAPRQTVSIKLDVPDQRRGDFHQIKDQFLHCANRAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVV1</accession>
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            <fullName evidence="4">Glutamate synthase domain 2</fullName>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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            <end position="467"/>
        </location>
    </feature>
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            <begin position="547"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="633"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="633" mass="68249" checksum="8C8D58C8CE3E7DA7" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="28755" checksum="FA2D651C6F666977" modified="2013-11-13" version="1">MVRTSPSLLTVRGRPHYYHLARAVLYREFLIFVRYPANAIGGIVVALLFFGGLFYGGQILAGQAITDSIEGLIVGYFLWTLSIGAYSSVSNDIGSELQWGTLERHITTPFGFAPVALLKGLAKLVRTGLTSAVVLAVMLALTGTRLSLAPLTVVTIAAATITSVLGLGFAAGGVTVLYKQIGNWLNLLQFGFVALISAPALEASWTRVLPLAHGSALLQRAMVDGVRLWQFGLGELGLLVGVAGGYLAGGYLVFHYATRRARRLGVLGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWD6</accession>
    <name>U1MWD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl dehydratase</fullName>
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    </protein>
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    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Halobacteriales</taxon>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="SSF54637"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="28"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="15769" checksum="76214D646A762126" modified="2013-11-13" version="1">MPDESLSGVDRDDWESSRSVSDPLAVGDTVTFTKTITDADVRSFATASGDTNPLHLDADAAAKTQFGERIVHGALGTGLIGAALARFPGTVVYLSQELAFNAPITIGDRPTARCELRAVLDGDRYRLVTRVGVEDIPAIDGEAVVLIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWG1</accession>
    <name>U1MWG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sec-independent protein secretion pathway component TatC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00605</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00605"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031942_8_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="248" mass="27182" checksum="47D3503FA177DC9A" modified="2013-11-13" version="1" fragment="single">MTAGRQNDAGSATVVDGAETAGELDTPGAPDDEEMPLSEHIEEMIRRLGIVLLCLGAVGLVTFPFADRLINFLWYSYLPGNPAACSTQPAFETMPTHAIVHSLPDEGGSVACPRLYHPLSLLLARIKVAALVGFVVALPVLVYQTYRFMRPGLYPNERRYYLSSVPTSLLLAAVGIAFAYFLVLPFVFTYFLFYSQDVAGIAFGLGDTLDIILLMMGLFAAIFQIPLFMMLGVLMGVVSQRWFADKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWI1</accession>
    <name>U1MWI1_9EURY</name>
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        <submittedName>
            <fullName evidence="6">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00630</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88485">
        <property type="protein sequence ID" value="ERG88485"/>
        <property type="gene ID" value="J07HX5_00630"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="41"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="508" mass="54741" checksum="C114221AD5F2C0FD" modified="2013-11-13" version="1">MSVDNEAQTPAERKSAIEQRHEQTASEVLPDHRGLYIGGEWTQSASGETFETRDPTTGKALAEVQAGAGADVDRAVQAAWDGYDERLSAMSTAERQRMLETIADRVAAKSAEFARLESLDNGKPITEARIDIDLVVDHFRYFAGMARAHEGETVTTDDSRHVQTLQEPYGVVGQIIPWNFPLLMAAWKLGPALAAGNAVVLKPAEQTPLSVLKLMEEADDVIPDGAVNVVTGFGEDAGAPLADHDEIRKLAFTGSTAVGRKVMKAAADSITDITLELGGKSPLVVFPDADLDQAVQTTLTAIFFNTGECCCAGSRLFVHEEIKDAFMNKLADAADSLEIGDPLLESTDLGPKVTAEQVERTMGYINEARDAGAELVTGGDAPDDEALADGCFVTPTLISQIDHDNRAVQEEIFGPVQEVFTWSDYDEMIELANDVDYGLAAGILTEDLTKAHECAKDIEAGNIWVNTYNDFPAGQPFGGYKQSGIGRETAQEAVDHYTQTKTVNIALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWT2</accession>
    <name>U1MWT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00578</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88433">
        <property type="protein sequence ID" value="ERG88433"/>
        <property type="gene ID" value="J07HX5_00578"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2473948_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="9354" checksum="C49B0497C762CD92" modified="2013-11-13" version="1" fragment="single">LPRGHTGVGGGSLSARLRHRLTLGRRTRNHRLVVGMTKFSQTGHLLVEIDIGSDVSAQVGQRGPGDAHASERSENPLSAYSFHLIVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWT3</accession>
    <name>U1MWT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00756</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88610">
        <property type="protein sequence ID" value="ERG88610"/>
        <property type="gene ID" value="J07HX5_00756"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3178441_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="46" mass="5012" checksum="C1B5690C92994F1E" modified="2013-11-13" version="1">MITGIRAECIADNNTDDRQAALNDTAPEGTDRGLAWFVRRALTGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX61</accession>
    <name>U1MX61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00719</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88573">
        <property type="protein sequence ID" value="ERG88573"/>
        <property type="gene ID" value="J07HX5_00719"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110565_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007386">
        <property type="entry name" value="DUF447"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04289">
        <property type="entry name" value="DUF447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="201" mass="22234" checksum="0639B94905B159B6" modified="2013-11-13" version="1">MTADGWPVKLRGVTETLVTTLGPNDRWNVAALGVHPPATDTDPDLDPSPVPTARTWGRTRTWRNFTERGEGYVQFTRDPELFVEAALAITEREDPVLAASDAWVRVETTATGSGETGGTEWTDWRLDARESAVCREVVPSFSRGYAAVVEATVAASRLDVPEYDTDTLRDRLNYFTDVANRCGDSAEQAALDRIWELVETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXA0</accession>
    <name>U1MXA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00764</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88618">
        <property type="protein sequence ID" value="ERG88618"/>
        <property type="gene ID" value="J07HX5_00764"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2983341_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6290" checksum="C12DC359EF4C0C6F" modified="2013-11-13" version="1" fragment="single">METAILPTAVEEYLTNNRSALFERTERLLAVDTQNPPGATDTVVEQLAAELGAAGIETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXC5</accession>
    <name>U1MXC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytoene/squalene synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00789</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88643">
        <property type="protein sequence ID" value="ERG88643"/>
        <property type="gene ID" value="J07HX5_00789"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031981_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="PTHR11626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="29211" checksum="299CED60BDC8DAC0" modified="2013-11-13" version="1">MTVESFREAVDPWLPPDEEWSDDWRVVAAAPTVHATVASLSAETQAAVRPPVRELVQGMATFIDRYAGAGGIRVQSRDELEEYCHYAAGTVGGLITRLLTPEATTEQATTMSQTAESFGRLLQLVNVAKDVYDDYTAENNVYLPAEWLTAEGVTQESVLAAGNRTGAARVVERTAALARSYLDDAGTYLSAMPLGRGNTLAAWAVPYLLAVGTLREIETSPATALTNERIAVSRDEVFAVVRAVQRGERSDIPKLRANIARGPLQSDLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXG3</accession>
    <name>U1MXG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00834</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88688">
        <property type="protein sequence ID" value="ERG88688"/>
        <property type="gene ID" value="J07HX5_00834"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954579_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="13797" checksum="DEB9FA8631312BA0" modified="2013-11-13" version="1">MVSGAAFSSAGSAHAVQGEQLRTHNGVFGSGRHAPWRGDRAGHVKPKPGLDTSHGHMRPITNTPLARDGKMLILAYDHGLEHGPVDFEPVPESADPEHVFELATHPAVQASRYRKALQRRSIPSTVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXL8</accession>
    <name>U1MXL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01021</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88875">
        <property type="protein sequence ID" value="ERG88875"/>
        <property type="gene ID" value="J07HX5_01021"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243733_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11637" checksum="ADD7469688086BF0" modified="2013-11-13" version="1">MFSEVNNVVARIAPVYYLTLPRPALRRRKVQSVTDCSRDPEQFVTRACGKQVTGDRTSQKCQNIHRLSLQLSDNLPPAGPIAKPPKPALVTPGRLLLQRFKENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXN1</accession>
    <name>U1MXN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01036</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88890">
        <property type="protein sequence ID" value="ERG88890"/>
        <property type="gene ID" value="J07HX5_01036"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3379858_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3726" checksum="0D3C1B152DB1CC49" modified="2013-11-13" version="1">MAGDMLTPFIGDEEIDPQSDAFSQFVMKIAYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXQ7</accession>
    <name>U1MXQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01066</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88920">
        <property type="protein sequence ID" value="ERG88920"/>
        <property type="gene ID" value="J07HX5_01066"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077931_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="266" mass="27109" checksum="20DADD9209E9B712" modified="2013-11-13" version="1">MSPDVVHNVIAATCDPVSNLKLAVHPLSRCPCQFDCLLATAAASFIPLLPITGLPMSEEAADGAVASYRAARTRAFAYPREADLVHGLELAALGAVLTGVAAQVSIPLPFTPVPITLQTFAVLLTGVTLGARFGGASQALYVGLGAGGVPWFEGFGAGVGALAGPTGGYLVGFPVAAVLAGAAVDRYPVTRRLPVLLVVLGLANAVVFAFGLPWLYTWLTVINGDPLSLPELANKGLIPFIPGGIMKTVGAALVATAFLPGPSERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXU4</accession>
    <name>U1MXU4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Argininosuccinate lyase</fullName>
            <shortName evidence="1">ASAL</shortName>
            <ecNumber evidence="1">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argH</name>
        <name evidence="4" type="ORF">J07HX5_00974</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88828">
        <property type="protein sequence ID" value="ERG88828"/>
        <property type="gene ID" value="J07HX5_00974"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_3_2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="2">
        <location>
            <begin position="25"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="3">
        <location>
            <begin position="358"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="478" mass="50110" checksum="05B4580D4637EE54" modified="2013-11-13" version="1">MTDEPAVRRDRFTGGPARSFLSSLAADSRIFAADIAVDQAHVVMLAEQEIVADETAGLILEALAAVETAGHAELPSGEDVHEAIETAVIDRIGSDGGRMHTARSRNDEVAACLRYRLRADLLGLLDRLCDARSRLQAVAAAESMTPMPGYTHLQPAQPTTVAHWALSYEAALARDTSRLRDAYDRLNRSPLGAAAFAGTPFPIDRERTADLLGFTGVVENATDAVSTRDFLLEVAGALATTAVTVSGLAADVIEFVSRGLMTVDDDYASTSSIMPQKKNPDTLELARARAGDASAALSALVTTLTGLPRAYNRDLQRVTTHFWEAVDETGPAVAAAVGAVATAEWPSDQLAAAATEGFAAATGVADRLAMAGVPFRTAHELVAEVAAAAAGTPSLEAVQAAVSELAVELDDETLATVLTAEGSVAMRDSRGGPAPAAVAAQRDRAETTLADHRDATDDRRQRVDAAATRLATAVDRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXV3</accession>
    <name>U1MXV3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">2-(3-amino-3-carboxypropyl)histidine synthase</fullName>
            <ecNumber evidence="3 6">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00984</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DPH1/DPH2 family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88838">
        <property type="protein sequence ID" value="ERG88838"/>
        <property type="gene ID" value="J07HX5_00984"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037146_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022428">
        <property type="entry name" value="Dph2_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="PTHR10762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03682">
        <property type="entry name" value="arCOG04112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="350" mass="39104" checksum="5C8787D8439DE713" modified="2013-11-13" version="1">MSHDTAEQPDGDLRATGMSLRHDREWNYELERIVDEVEERDAESVGLQLPEGLKRRGPGVADDLRRRLDGVSVLLSGQPCYGACDLDTYLMRRTDVFVHFGHSPMKESDKIIYVPLFSNVDVEPAIDRAVAEELPPASEEAALGLVTTAQHMNKFDEMRAQLETAGYDVKTRRGDERLTHEGQVLGCNYASAEVDADQTLYVGGGKFHPLGLAMEHPEQHVVIADPVNNVVTVADTEKFMKQRYAAVHKAMDADSWGVIYCTKIGQGRWDEAEEIVESNDDAYMIAMDEVTPDRLRNFGLDAYVNTGCPRITTDDGPQFHAPMLTPGEYKIAVGEKPLDELEFDTFHGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXZ2</accession>
    <name>U1MXZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-polyprenylphenol hydroxylase related flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01181</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89030">
        <property type="protein sequence ID" value="ERG89030"/>
        <property type="gene ID" value="J07HX5_01181"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="25023" checksum="EAB5B7C3C1EA93B7" modified="2013-11-13" version="1">MAFDDATITDVTEISPDCKQYIIELNDGSFTGEAGQHTAIQTDNGVKPYSVLAVDETRIGLMLRAYGTDGVADYMDARSAGDTVQVKTRLTGSLTLRRTDRPAVFIGTGTGITPLIGLLQAYIAKDGPQAVFMFGEKNRDQLLYKSLLEQYELTNPVETRFSLSREEWHGHTGYIQDQLPGVIDTVGDDVDYYACGVPAAVVAAKDRLDELGVPADRVHTEGWEEARVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY76</accession>
    <name>U1MY76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Diphthine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01278</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diphthine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89125">
        <property type="protein sequence ID" value="ERG89125"/>
        <property type="gene ID" value="J07HX5_01278"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066040_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004164">
        <property type="term" value="F:diphthine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="PTHR10882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="254" mass="26899" checksum="029AD3B5A56AADEB" modified="2013-11-13" version="1" fragment="single">MLSFIGLGLYDERSITVRGADRLTAADKAYLDVYTSRLAGTTVEELRAAHDTPIELRDRAGVERDPTPILSTAEQGHAAFLTAGDTMISTTHTDLRLRAQSRDIDTTVILGTTAQTAASALTGLQNYRFGKATTLPFPDVHGGVPDSVVDTLTNNRASALHTLVYLDIDAANDRLLSADRAAELLAEQTPIDGPAVVVARAGGADTIVRAASLDTLASLSFGPPPHLLVVPGELHQMERAALTALADLPEAEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY93</accession>
    <name>U1MY93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type phosphate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01138</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88988">
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        <property type="gene ID" value="J07HX5_01138"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1639928_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20017" checksum="D696EFBCCCBDDE68" modified="2013-11-13" version="1" fragment="single">FLGDPPSMTVEELAQIWESDSAATWNEVNSNWPDQEIDRFGAADTSGTYDYFIENVQGTERGHTDDYNPTEQDNTIAQGVEGSEFGIGYFGFAYFFQNPEQVTAVAIDNGDGPVEPSLETAASGEYQPLSRPLFTYPSVSSLGEEHVAEFARYFVNQTTDEQLVAENVGYVPLGEDQQQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY97</accession>
    <name>U1MY97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative divalent heavy-metal cations transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01298</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89145">
        <property type="protein sequence ID" value="ERG89145"/>
        <property type="gene ID" value="J07HX5_01298"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015114_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ZIP"/>
    </dbReference>
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        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="265" mass="27187" checksum="FB8D45E02B48FD42" modified="2013-11-13" version="1">MVAAESLLFVFLAGLVTALATGIGVLPFFLVEEITTRQNVVLWGFASGIMLSASVFGLVEEGLTEGPPGEIVLGAGAGVVLVAVSGRMLSAATIDPRQYEQANFAKLVLILGVLTVHSFPEGVAVGVSFADLGRAGGVSVLGASVPALGVVMTIAISIHNIPEGTAISIPLRSMGVPKRRMVWWSVFSSLPQPIGAVIAFIFVRTARNLLPVGFGFAAGAMVYLVLAEFVPEALATGSALPRGGRPELIAGVFAGVGLILPLAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYC3</accession>
    <name>U1MYC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gas vesicle synthesis protein GvpL/GvpF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01168</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May play a structural or regulatory role in gas vesicle synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
            <location evidence="2">Gas vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89018">
        <property type="protein sequence ID" value="ERG89018"/>
        <property type="gene ID" value="J07HX5_01168"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065736_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009430">
        <property type="entry name" value="Gas-vesicle_GvpL/GvpF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36852">
        <property type="entry name" value="PTHR36852"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06386">
        <property type="entry name" value="GvpL_GvpF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="212" mass="23169" checksum="BDCE9847F5736613" modified="2013-11-13" version="1">MSTNVYTYGIISQESLELSVNGVAGADSVYTVDHRSLSAVVSDIETTEPDRTDEAVETHNNVLQQILEYDGGRTVVPMSFGMGFKDTRTLKGVLRGARPTIESTLEKISGTVELGVKIIAPATGRLSRDAVQSTTTELLSAASINETDNDLFTDRLIVNKSYLVDRDHREAFDDAVDEIEAEYGDTVTVQYTGPWPPYNFVDIRIGADQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYM1</accession>
    <name>U1MYM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS domain S-box/VCBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01427</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89270">
        <property type="protein sequence ID" value="ERG89270"/>
        <property type="gene ID" value="J07HX5_01427"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022064_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010221">
        <property type="entry name" value="VCBS_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01965">
        <property type="entry name" value="VCBS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="140"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="215"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="267"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="377" mass="41821" checksum="22715B0E75CD1137" modified="2013-11-13" version="1">MCATHQQQVEVLHVDDDPDFTELAKGFLERKDSQLTVETATNTDEGLQHVSDRPPDCVVSDYNMIGMDGIEFLETVREDHPDLPFILFTGRGSETVASKAIAAGVTDYLQKDSGVEQYELLANRIQDAVEAQRGAEQVTRQEQLMRLTELAGDTGGFEVDLETGAVLLTAGTRRLVGLPEETQITLEEAINFYHPDDQADVRQTVIQAAETGDQTRGSWRLQTTDGEQRFVDVTITPATEGNDTAIVRGAFRDVTEQRAREQKLNAEQRIIEQALDTLDSLFYVLNTDGTLRRWNTKALELTGYTEQELAEIHATELFAYDDRETIRDAIETTLVDGQVVVEAALLTANGECRSYEFTGRQLTDADGNVTGLIGIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYN4</accession>
    <name>U1MYN4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase II large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">J07HX5_01296</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal DNA polymerase II family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89143">
        <property type="protein sequence ID" value="ERG89143"/>
        <property type="gene ID" value="J07HX5_01296"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_682418_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004475">
        <property type="entry name" value="PolC_DP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016033">
        <property type="entry name" value="PolC_DP2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42210">
        <property type="entry name" value="PTHR42210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03833">
        <property type="entry name" value="PolC_DP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolC_DP2" evidence="13">
        <location>
            <begin position="3"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="140"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="403" mass="42889" checksum="585F891A275B1231" modified="2013-11-13" version="1" fragment="single">LCGRTAQALSVLVADYARSLLGIGAYQARDPEVGRYAEEVALYDGETGLQYAPSEAEARFIANHLPIMLDGEPTSDGDVEGYRDLERVSTNAARGGMCLVFGEGIALKAPKIQRYTRELSAVAWPWLQTLIDGDYAAAHSNDDDTTNTDADADADTEGETEAGPESDIGSEADNPTPSDDTSEIVGGPGSATTAAGDDTATQSPSASGPRPEPTDKFLTDLIAGRPVFSHPSEPGGFRLRYGRARNHGHATAGVSPATMHLVDDFLAPGTQLKTERPGKAAGVVPVDTIEGPTVRLATGEVRRIDDAAEALELRNGVERVLDLGEYLVNYGEFVENNHDLAPAGYTVEWWLQELAAAGAPVQALRDAPEINLTDPAPERALAWADADVPLHPAYTYLWHDISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ17</accession>
    <name>U1MZ17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01568</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89410">
        <property type="protein sequence ID" value="ERG89410"/>
        <property type="gene ID" value="J07HX5_01568"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073311_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="297" mass="29921" checksum="33445530E2B2B87A" modified="2013-11-13" version="1">MSDQPAVESARSESATGSRLDTAIGYVELGRPVNAGLLAMFGVVGAYIAGGATAATGPGMTAGAVTLLAVVGGFAVNDYFDRDIDRVNDPERPIPRGAVAPQNALIIAAVAFGSAGTIAVTALPSPAAGVVLVSIVALVVYTPLIKGRYGLGNLLIAGLVGVAAALGGLVTETPGPAVVMGLLATQMLFGLEVLKDLEDVVGDKKAGLQTLPLVLGQRTAVWIILGVLAATVPLSLVPVVRETFGLAYLLVIGVAHVLTGITMWATVARSPATALSVIKPAMAVCMMAFVAGRMVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ32</accession>
    <name>U1MZ32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01589</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89430">
        <property type="protein sequence ID" value="ERG89430"/>
        <property type="gene ID" value="J07HX5_01589"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1323275_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="38"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="209" mass="22324" checksum="6BD83A0492D0DDA1" modified="2013-11-13" version="1" fragment="single">MFPWLDTITMTEQSVDGHNAEFDGIGRDHGGIKQWFRQAGAFAKRHLRVTARNKIIVALLVGYPVVWFISTLWLFVEDPGATAITAIGVGFGLFGALTATLAVFAGEFARDLQRDRYAKFRALPHAPSADLAGRFAAGTVVGSVSYLVTLAAAYLAGGTFEAWLSPTAWVPALFTLVAFCLIATSLAILVGAAVPKPEYMTVFAVVGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ61</accession>
    <name>U1MZ61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar kinase, ribokinase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01636</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89475">
        <property type="protein sequence ID" value="ERG89475"/>
        <property type="gene ID" value="J07HX5_01636"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="5"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="31602" checksum="D93710980695ED62" modified="2013-11-13" version="1">MSPAVVGVGNAHLDRTHVVTSIPGPDEGAYALDSHTIVGGVAANVATGLARLGHDTGVIARLGDDADGRQVQKELKRDGLDVERLRLVADEASSYTLVLRTPDGQRAIVGGGESSLRLRLRAPDTAYLGGATVAVTSGYTPAIVLQALLDRAIDPRPAVVVDLAGTMDELRARGYTEAVLDRLLPRAALVVGSASAVASYAGTDTATVAALRDRGVDQGAITRGADGAQLWNSETVVDLPAFDVTVADTTGAGDAFTAGLIDGLVCRDCRLRAAGEFAAAAAALNCTTVGARPGLPTRKAVEAFLRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZQ7</accession>
    <name>U1MZQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01867</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89695">
        <property type="protein sequence ID" value="ERG89695"/>
        <property type="gene ID" value="J07HX5_01867"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026973_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="3">
        <location>
            <begin position="206"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="475" mass="50611" checksum="5C2556D110100E33" modified="2013-11-13" version="1">MSDATSAHTDGDLSHSRERRQPWSIGLVATLVLVALGLLYANTTLLAAATVPLVYLVYGTVSTLPAEPSVAVKRTLDPQVLAPGDHVSVTLAVTNTSDRLLTDLRLIDIVPEPLAVTSGSPRLGRSLRPGETATTTYVVVAKSGEFAFGPPAVRLRSLADSATLNMEVPAAGDTRLTATTAVAEPPRQPTALPRDGQQSADDSGTGREFYATRPYQPGDPIRRINWRQFAKTGSLTTVQYRQEQAAETVVLVDCSPLGLAAPRPGQPTATELTGYAAERLHAVLQDAGVVTVVAAARADTQVPPELIATDGLSWIDSTDKRGRTAADRLLRSLQGEASGRAEPLALLPPGIDLGAKTDIGDRHHDTDAATEPTPIQSILTRLSSNAQVIVCTPLLDDWPVDLVTALQTRAYSTVVITPDATTTTPTPTPGQRLAGVHRQLRLDAIDRRGGRTVDWSPDRPIDRAIRASLPQRLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZU1</accession>
    <name>U1MZU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01902</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89730">
        <property type="protein sequence ID" value="ERG89730"/>
        <property type="gene ID" value="J07HX5_01902"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2946824_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6695" checksum="1581E863AC6A4008" modified="2013-11-13" version="1" fragment="single">GYVFRAECLLDYPLGILCVECCDSLAQWLVACLSERAGMIGYVRQCSDAVVGHRDRSRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZU5</accession>
    <name>U1MZU5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01907</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89735">
        <property type="protein sequence ID" value="ERG89735"/>
        <property type="gene ID" value="J07HX5_01907"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2230278_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="10663" checksum="FED27258A5FE135B" modified="2013-11-13" version="1">MCSLGAQFMAFASDLSAPGAVIRAQIGPDSHRRPISIDWSVIGVTHPPIGVSSDQARVACQVWDPVAGATDLLGSTTRLSRSSVSVGTRTCNGAIHSGVGGSASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZY9</accession>
    <name>U1MZY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01798</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89628">
        <property type="protein sequence ID" value="ERG89628"/>
        <property type="gene ID" value="J07HX5_01798"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2338248_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="97" mass="10387" checksum="8A71F252E2FEA9A8" modified="2013-11-13" version="1" fragment="single">DLDQAADVPLAHDGEPVDHANVERIDLTNVHHPQECRAQVRLQGSISDFHEGDSVTVGPTPLSKLQIDGTVDGQDDTTNAIILSIDGMEAPTETPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1N062</accession>
    <name>U1N062_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02012</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89840">
        <property type="protein sequence ID" value="ERG89840"/>
        <property type="gene ID" value="J07HX5_02012"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1168543_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="20"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="25518" checksum="3E58B5FBCB386ECD" modified="2013-11-13" version="1">MSKTVSTALADVSVEGTVCLDAGAGAGNSAAVLEDRGAGSVLTVTNNASQAASVRERFSTDSVVTTLHADLRAVPLPEDTVELVTAHALFNVVATPETAAIVRELTRVTAPGGRLVVDDYSPLPDGPVRDLFGAANAVGELNTARPTYTFYPREHLRWLFEHAGWTHIRTTNLLDPVPWPADMLDTHAELIANQAATFPDELANGLRDRTSMTREQGGDGVETGEMYSLLFRLPHELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>U1N082</accession>
    <name>U1N082_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ORF">J07HX5_02022</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89850">
        <property type="protein sequence ID" value="ERG89850"/>
        <property type="gene ID" value="J07HX5_02022"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="101"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="406"/>
            <end position="409"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="435" mass="48577" checksum="7AF98976C437EEBC" modified="2013-11-13" version="1">MDPDSRTYAVDATPDTKATLAGWVHEIRDLGGIAFLILRDTTGKIQVKVEKDTLEDELVETALDVHRESVVSVVGAVEEEARAPTGVEVVPESFELLSPADPELPLDPSKKVDAELPTRLDNRTLDLRKPEMQAIFEVRAEVLKAVRDQFRQLGCTEINTPKIVATGTEGGTELFPVTYFGQEAFMNQSPQLFKQLLIGSNLERVFEIGPIFRAEEHNTPRHLNEATSIDLEAAFFDASNAMDAAEAVVTAAYEAVADNCEQQLETLGLDEFAVPDAEFPRLTYQETIDRINATGKLDEPLVWGDDLSTEAERALGTAVGEHYFITEWPSEIKPFYIRDLDDNPEHSTGFDLMHPSMELASGGQREHRHDRLVAGFEQQGLDPAAFEYYTKMFRYGMPPHAGWGLGGDRLVMTMLELENVREAVLFPRDRQRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1N083</accession>
    <name>U1N083_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01900</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89728">
        <property type="protein sequence ID" value="ERG89728"/>
        <property type="gene ID" value="J07HX5_01900"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054903_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019293">
        <property type="entry name" value="ThiN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10120">
        <property type="entry name" value="ThiP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="31171" checksum="2481C64FD9311BC3" modified="2013-11-13" version="1">MRLIEEIVVEEFLPTFRSMLAAGLEERGLTQHEIADRLGLSQSAVSKHIHGEIDRTDQIASDERVQSVTTDLADGLASGDLTPTEALIETEHTVRELERGGVLAELHAAAVPELDPDMPVHGAADQLRETVRVRQSVRRGLRVLRAADGIAGAIPDVGANLAECVADAETIEDVVAVPGRLFALRGRLVVPDEPAFGVSQHVAGVLLAARRAGSDARAAVCVAYSQALVDDLAAAGHTAVEFDADAELTAAVSAACADRPVVDVLYQTGGFGIEPVVYVLGPDAPTAARSVRKCLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0B4</accession>
    <name>U1N0B4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02047</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89875">
        <property type="protein sequence ID" value="ERG89875"/>
        <property type="gene ID" value="J07HX5_02047"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177456_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="11762" checksum="00B88603E40D8530" modified="2013-11-13" version="1">MTYNIHIMEIASRRKLGAILAIVQGLITAVAPQLSTRITRQVIRGNFDNADDLVAKPGYVRRLRALGIGLAAAGIASFTMELVSENNDDNSTETATTDGDDDAVDVTVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0X7</accession>
    <name>U1N0X7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type Fe3+-hydroxamate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02146</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89973">
        <property type="protein sequence ID" value="ERG89973"/>
        <property type="gene ID" value="J07HX5_02146"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_9_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="307" mass="32889" checksum="C798B7592A33B0F6" modified="2013-11-13" version="1">MRVVSFLPSATEMLYTLGVEPVGVSHECDYPPAVEELPTVNSSPVDPDGSTAEINQQVADAQANGGVYEIDKQTLADLDPDVVVSQGICEVCAVDDGRIRDAVADLGLDAEVITTDPHSLEDVFDDLERLGRRLGREPQAEQAVADLQMRVRAIERATPAPEDGPDVAVFDWLDPVMVAGHWMPGLIERAGGRCELARHGAPSRPREWDAIRAHDPDVIVAAPCGLDLDRTLADADDLAGRPGWETLTAVQTGRVYAMDGHDYANSPGPRLVDTLELLAGIITPGRDELPASAVEQWPGLAANQPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P326</accession>
    <name>U1P326_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase conserved C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00013</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87872">
        <property type="protein sequence ID" value="ERG87872"/>
        <property type="gene ID" value="J07HX5_00013"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1274534_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="PTHR14025:SF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="217" mass="23216" checksum="3476CD500F059802" modified="2013-11-13" version="1" fragment="single">MTQTEQQATLEQFRAGEFEVLVSTSVAEEGLDVPEVDLVLFYEPVPTAIRSIQRKGRTGRQADGRVAVLLAEDTRDEAYFWKARQDEQAMEDELRELKGAVGEIEAELTQTTLPETDPAAGRGTEAAVSAGTETEPNETNTTINTDTAAGASSNGGKPPQADRTTKPDNQATATTQGGEHDGQAGLDAFAGDDNSNAEAEPEQTRRESATPTETETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P399</accession>
    <name>U1P399_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00108</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87967">
        <property type="protein sequence ID" value="ERG87967"/>
        <property type="gene ID" value="J07HX5_00108"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2818144_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7588" checksum="46837C08B870FEE3" modified="2013-11-13" version="1" fragment="single">SCKTRWSSDFIKKHNDNRIALSGNVIKDTLSSRALREGIMNLTTPVIYDGHVYWREEGKELLNPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3B1</accession>
    <name>U1P3B1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease VII small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00123</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87982">
        <property type="protein sequence ID" value="ERG87982"/>
        <property type="gene ID" value="J07HX5_00123"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199463_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6760" checksum="F041E03F2B5AB70B" modified="2013-11-13" version="1">MSETDADTIDRKVTRVEEIIETLEAGEVSLGEAKSLRDEGKALLGELEGDLDLGDGEIIERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3D7</accession>
    <name>U1P3D7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00153</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88012">
        <property type="protein sequence ID" value="ERG88012"/>
        <property type="gene ID" value="J07HX5_00153"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112567_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14935" checksum="EDCEE4397B900F92" modified="2013-11-13" version="1">MPLQSDTELRAVLQRTTTIAVVGCSSTPGKAAHEIPRFLHEHGYQIAPVNPYANAIFGIDAVDSLAELTGQIDLVNVFRPAAEVPDIVDTVLEREDVATVWLQRGIVHDAAASRVETTGRAVVQDQCMKVEYKRLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3N6</accession>
    <name>U1P3N6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PQQ_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00260</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88117">
        <property type="protein sequence ID" value="ERG88117"/>
        <property type="gene ID" value="J07HX5_00260"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177452_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PQQ_3" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8006" checksum="702872A639AAEF7C" modified="2013-11-13" version="1">MSKRTRREWLCLIGAGGVAGLAGCSLSGTEADGIEQWRFQVGDPVGSSPAVVDDTVYIGSRDGNVYALSNVDGESAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P410</accession>
    <name>U1P410_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrogen regulatory protein PII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00390</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88247">
        <property type="protein sequence ID" value="ERG88247"/>
        <property type="gene ID" value="J07HX5_00390"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082268_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="11696" checksum="4BDB4C23B6B58146" modified="2013-11-13" version="1">MVTAIIRPDRLSEVKTALAGVDAPSLTVTTVSGRGSQPPKTGQWRGEKFQVDLHQKVKIECVVADTPTENVVAAIEDAAGTDQPGDGKIFVMPITQALRIRTGERGTEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P532</accession>
    <name>U1P532_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RecF/RecN/SMC N terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00798</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88652">
        <property type="protein sequence ID" value="ERG88652"/>
        <property type="gene ID" value="J07HX5_00798"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="1">
        <location>
            <begin position="3"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="14947" checksum="95E5E329B9978159" modified="2013-11-13" version="1" fragment="single">MHITEIILDRFKSFGRETRIPFYEDFTTVAGPNGSGKSNVIDAVLFALGLARSSGIRAEKLTDLIYNPGHQNSKSFDDEREASVTVIFDNSGRTLSRTQVANAAGSEKIGDVDEIAIKRRIKETDEHYYSYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5H3</accession>
    <name>U1P5H3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00933</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88787">
        <property type="protein sequence ID" value="ERG88787"/>
        <property type="gene ID" value="J07HX5_00933"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1307812_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="207" mass="21987" checksum="20F21918279C77CE" modified="2013-11-13" version="1">MPSLLERLLGDDTPDEQVDLEARQSDANDALQDRINADSYGINKCGVTGVAVVNEGPDGKPVTVPIARFSLGEDVEDPDMDLIWDLVPEALLVLDNNFSDVFVRHYDVQFTFDGDELFEAEECRRVATPPAYAEELGTETMFDGDALRERLLTEHNIDDDVAPVAWGECKDYTNTNNTAVVTGGAVAAAAVSGSAASCAGAAGGGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5N5</accession>
    <name>U1P5N5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00988</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88842">
        <property type="protein sequence ID" value="ERG88842"/>
        <property type="gene ID" value="J07HX5_00988"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_910905_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="305" mass="33274" checksum="58DBC9B821CD5ADF" modified="2013-11-13" version="1">MDSNDVPLKRRDAIKAIAGAGMAGAGLATTTPAAATKQSVETSSNAKPGTDELVVNYFEYYSHDDSSELVKEADFTIETSEWGAYDPDNVDGCPGPGDCWTYSGTVYDPDDAGWNETSSHRYERLSDEFYRTIDHNGAVTWYSWDQYSCNTISSPSYYNSSYELEVSGVGDYLVLTGLQNAYHRYSSNYLRAYKVDVDGIGGITIPWIGTGVGKSVKIGGVREDQPVEEDTASITKQHKECDQDQDSGWSWGEIEYDSAGLVGKVEDGTDTWEIGVGCFPGDIILGGDIELTISEWSGESNFDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5U4</accession>
    <name>U1P5U4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01033</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88887">
        <property type="protein sequence ID" value="ERG88887"/>
        <property type="gene ID" value="J07HX5_01033"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1830640_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="15590" checksum="0754F7A690F1694D" modified="2013-11-13" version="1">MTIRVSRTLNFEAPAGSVWEFISDPAKRAGAISVVDSWDVHDDVSATWQVALPIPVIDSTVAVETEEIEQNPPTHVKFVGKSRALRVTGEHDIEATDSGSQLHNEFVVDGRLPGVETFFSRNLDRELDNLEQALLDSFENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5V4</accession>
    <name>U1P5V4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylsulfatase A related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01048</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88902">
        <property type="protein sequence ID" value="ERG88902"/>
        <property type="gene ID" value="J07HX5_01048"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_14_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="1">
        <location>
            <begin position="74"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="501" mass="55609" checksum="ACCECC60C5548742" modified="2013-11-13" version="1">MSLISINGWLCKSPRHLPRHAYAFSKLFSPRSRVWPQLHNRGERLIDRPSPQVRDQAIRLGIAWVSFEPMAPIRNVLLVSVDCLRADRFREGIEDGLLPNCAALDSGATTFESAYTVANTTDPSLTSFMTAQYPFGHGVVENGWGLDESEPVAAERFRAAGFDTFGVVSVDHLAHEHSRLGRGFDQYHDGGSSYDTLYPILSRIYDTKTFNTVFGAIKTLGIGRYTVKNLLRDLGLISLHCRPASGVTADATASLDNADAPFFGWVHYFDVHEPRNAPRDLLGDHDEYTAAMMRVDEHVGKLLAELDTLGIRDETLVVLTGDHGEALEDHGYTGHGRTLYEEELHVPLVFAHESLPDRTVPTQVRTIDILPTLLSMVGADPLDAAGTPVVDGPHDGTKHTAPIDEDRPLYAMAYPTFGEGVALRRDDWKLVRDQEEETEELYDLSADPTERTDLVDDAEVSTRWKSMATDLDAWLGGFGETDRQEVDAETEEMLADLGYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6J2</accession>
    <name>U1P6J2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydrogenase maturation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01346</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypE family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89192">
        <property type="protein sequence ID" value="ERG89192"/>
        <property type="gene ID" value="J07HX5_01346"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041631_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005644">
        <property type="entry name" value="Hdrgns_mtr_HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="94"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="205"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="382" mass="39230" checksum="795A6974BB88E994" modified="2013-11-13" version="1">MSGGLNAQLPGDLITDACRSKQLLGRGTDPRTRSAAGTKPLEQFIPHMPDTGKINRSLFDRVIRPQLGATRPDVIVGPTSGIDFGVVERGEQAFVVATDPVSVLPELGLSRAGRFATRIVLADAAVSGLAPTHLTISLALPPALGDDAFARLWQGVHETCRELGVAVTTGHTARYDEAQFPWVGAATAVAVGDPAAVVRPDGASPGEKLLVTKGPAVETTGLLTTLFPDQLPLSAETLATAQQRLGETGVVRDAVAAAEAGASAVHDATEGGLLGALHEMAAGADVGIAVDTDQVPVRPGVSAVCETLEMDPWTATSAGTLAITAPADDADAVAAALAARNTPVSVVGSVTDDAGVRLDDTPRSVPDQDASWPVYDRLTKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6M1</accession>
    <name>U1P6M1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01377</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89222">
        <property type="protein sequence ID" value="ERG89222"/>
        <property type="gene ID" value="J07HX5_01377"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023125_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="52"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="252" mass="28182" checksum="3DB10E3151F2527C" modified="2013-11-13" version="1">MSTQDRSPEPAERYTVLDEREEKAAHTKTPMTFGDTVTPYHWRFDPAAHDEIYIVGDIHGSIDELKRLWAQLTPSGDDLVVFVGDLVRKGPASIEVVEFIAESPHAVSVKGNNEMKLVRETVETAPFEPVLETVTALPLVVSFGDSMVVHGGIHPEWELVEHEPDDLLEMRSVPRGNSYDGPFWFEQYTDSPRVFFGHTVLSEPYVSDSAVGLDTGCVYGGELTAYDWRRDELVSVSASGYQSRPDRKILSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Y6</accession>
    <name>U1P6Y6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00007</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87866">
        <property type="protein sequence ID" value="ERG87866"/>
        <property type="gene ID" value="J07HX5_00007"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954573_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14364" checksum="54D42B220C4AFA9B" modified="2013-11-13" version="1">MQKMVFPAREFAAGTTRPFRWAVFSFSLVFFTGEVVSVLFQPVAGVQFTWAVLAVDSQVVTDSEVDFSNVFAGCIFNGNFLLTYQMQFPSVAVPDGTRLLDVLDGHIWPYLVFHENEVWPAIFAVPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P760</accession>
    <name>U1P760_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative nuclease of the RecB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00102</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87961">
        <property type="protein sequence ID" value="ERG87961"/>
        <property type="gene ID" value="J07HX5_00102"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2627438_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002793">
        <property type="entry name" value="Endonuclease_NucS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38814">
        <property type="entry name" value="PTHR38814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01939">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8668" checksum="52F72686027F70E0" modified="2013-11-13" version="1" fragment="single">MNYRIADQPTPATVEELLGEAKRRSACLSIFTECTVEYDGRANASLASGDRLVMYKPDGTVLVHTDEQRTPQNWQPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P780</accession>
    <name>U1P780_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01560</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89402">
        <property type="protein sequence ID" value="ERG89402"/>
        <property type="gene ID" value="J07HX5_01560"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2338247_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="10635" checksum="345DA74299984B12" modified="2013-11-13" version="1" fragment="single">MREDADHGREPDDPRSIAVDPPVHVESYSSHTSLSWTASGIDQFVAALRASETVPADTTPVVDATTAAGQRRLRLDEIDTMSGATKYVRVEPSAPWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7F9</accession>
    <name>U1P7F9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA or RNA helicase of superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00218</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88076">
        <property type="protein sequence ID" value="ERG88076"/>
        <property type="gene ID" value="J07HX5_00218"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_429389_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="175"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="3">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="637" mass="69988" checksum="E62C785A47301F0B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7L8</accession>
    <name>U1P7L8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01718</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89552">
        <property type="protein sequence ID" value="ERG89552"/>
        <property type="gene ID" value="J07HX5_01718"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257255_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11280" checksum="921FCF674AD9D911" modified="2013-11-13" version="1">MISLGVRVAVVAVCGLVTWYSVTEVTIRSGVYVQAGAGLIVGLLVYVGLAFVSGADRRRRRVNLAPVSAQESFGSLCKTTWRAQHIRSSVSTLRRYPPMVVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7S5</accession>
    <name>U1P7S5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit PurQ</fullName>
            <shortName evidence="1">FGAM synthase</shortName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Formylglycinamide ribonucleotide amidotransferase subunit I</fullName>
            <shortName evidence="1">FGAR amidotransferase I</shortName>
            <shortName evidence="1">FGAR-AT I</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glutaminase PurQ</fullName>
            <ecNumber evidence="1">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purQ</name>
        <name evidence="2" type="ORF">J07HX5_00339</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EC" id="3.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88196">
        <property type="protein sequence ID" value="ERG88196"/>
        <property type="gene ID" value="J07HX5_00339"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001031_3_1_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
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        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
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            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="243" mass="25446" checksum="F4ABA1580068BF3A" modified="2013-11-13" version="1">MTVTVVRFGGSNCDRDAVRALGQIGVDAEIAWHGDGLPDTTAGIVLPGGFSYGDYLRAGAMAAHAPVMTEVRDRLAAGVPVLGVCNGAQICCEAGLVPGAFTVNASARFRCDHCFLRVETADTPWTAAYDEGEVIELPIAHGEGRYVADEGTLNQLRADDRVLFRYCEPDGTVTDAANPNGSVDGIAGLTNKAGTVAAMMPHPERATLPTATTVDGRGILAAFARSVDDPLDTPESRVDSNQK</sequence>
</entry>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </feature>
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            <dbReference type="EMBL" id="ERG88241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="34" mass="3575" checksum="2EA0C0D20E512BBD" modified="2013-11-13" version="1" fragment="single">MRRVNVHAALAGTGQILSVAGEYILLARIKPKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
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    <name>U1P7Y7_9EURY</name>
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            <fullName evidence="7">Lhr-like helicase</fullName>
        </submittedName>
    </protein>
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        <name evidence="7" type="ORF">J07HX5_01849</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Halobacteria</taxon>
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    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89677.1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="37"/>
            <end position="167"/>
        </location>
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        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18014" checksum="0CDD5759EBA194F0" modified="2013-11-13" version="1" fragment="single">MTEATGAGAFAALGPAVRTALSERGFDAPTEPQRRAIGPLAAGDDALVVAPTGSGKTETAMLPVFDAIAGEPVFGIQALYVTPLRALNRDMRQRLEWWGETLDLEIAVRHGDTGDYQRRQQAEDPPDVLVTTPETLQALFTGKKLRRALEDVSHVVIDEVHELAVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Z7</accession>
    <name>U1P7Z7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+-dependent transporter of the SNF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00414</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88271">
        <property type="protein sequence ID" value="ERG88271"/>
        <property type="gene ID" value="J07HX5_00414"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006855_3_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="197"/>
        </location>
    </feature>
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        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="329"/>
        </location>
    </feature>
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        <location>
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            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="476" mass="49736" checksum="95AF81F08A38A29C" modified="2013-11-13" version="1">MTREHWKTRSGFILAAVGSAAGLGNIWRFPWMTAENGGSAFLLLYLLVVGLVSVPAVLGEFIIGRRAQCNPVSALHALSGSRTWRAVGLIFSVGTMIFLLSFYSVVGGWIVRYLADSATGAYYGAPGQHFNAISFRPAAVGFQALFLGVTALIVAGGVQRGIELAAKVMVPAIVAVLMMLAVIAPTLDGAGAGYGFFLGVNWTYLQGNFLAVLGDATGQALFTLSVGAGNMIIYASYLGTDRSLLTDGSVIALVNVLIGVITGLVVFPLLFALGVGPGGHGPGAVFVSLAQAFETLPMGRLVGVVFYTVVLLAALSSAINMLEVIVSFVIDEFGLDRQVTVAGLTVLFLFTGGVNAMEPGVFNFVANTLIDLLLYLGLTAFLLFAAWVLGGRALEELTAGGGTVAQTVAGPWRYWVGAVIPVFLMFTFFSTTASAAGYNVPIHWVGAAAVVSVGAAIGVLSRTNTLQRRELDSVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P856</accession>
    <name>U1P856_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01914</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89742">
        <property type="protein sequence ID" value="ERG89742"/>
        <property type="gene ID" value="J07HX5_01914"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529173_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="19172" checksum="A920724089A06F5C" modified="2013-11-13" version="1">MSPRWWTVLSLGVIVLGVTAAAGGVAGGTDDAWNGGQQNQPVAASQTQVLPQTEEIPEADATVTRITVAPNGTAEWRFRILIALDTNESVEEFAAFEREFATNQSQFLDRFRERITGVVDSARNETGRSMTAGEFTVETGTDELVAQRRGFVNYEFQWQNFAATDDGTILFGDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8E4</accession>
    <name>U1P8E4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01994</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89822">
        <property type="protein sequence ID" value="ERG89822"/>
        <property type="gene ID" value="J07HX5_01994"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049413_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="22530" checksum="00B1FA19F38F1286" modified="2013-11-13" version="1">MPSSGPHQGQPTRTAGAPLETADAVVVLVHGRGATAESILDLADELGHEAVAYRAPQAAARTWYPNSFLASVTANEPGRSSGLERIDNLVAGATAAGVPTERIIVAGFSQGACLASEYVTRHPRRYGGLAALSGGLIGASVDKAAYQGDLAGTPALLGCSTDDPHIPAARVHETAAVLEELGATVDTRLYEELGHAVNDDELTAVKQLIDTAVERTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8J1</accession>
    <name>U1P8J1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Malate/lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00586</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the LDH/MDH superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88441">
        <property type="protein sequence ID" value="ERG88441"/>
        <property type="gene ID" value="J07HX5_00586"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045401_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="7">
        <location>
            <begin position="147"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="304" mass="32045" checksum="A96C60421D9A3DF0" modified="2013-11-13" version="1">MTKVSIIGAAGTVGAAAGYDIALRGIADELVYVDIPEQQDTTVGQAADTSHGLAYDTNTVLTQGDYAATAGSDVVVITAGLPRDPGDTRLDLAANNAPIVAEIERALAEHSTEYVTVTTSNPVDLLNRHIYETGDRHRQRVIGFGGRLDSARFRHVLARRFDTPVGNVEATILGEHGDAQVPVFSKVRIDGRDPSFDDDERAAILKSLQTSAMAVIERKGATQWGPARGIGHVVEAIVRDTGTVLPCSVVLDGEYGRSDVSVGVPVKLGAGGAESVVEWSLADGEQAGLERAATKLADQYAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8N3</accession>
    <name>U1P8N3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02059</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89887">
        <property type="protein sequence ID" value="ERG89887"/>
        <property type="gene ID" value="J07HX5_02059"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180506_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036809">
        <property type="entry name" value="AF1782-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023140">
        <property type="entry name" value="DUF357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04010">
        <property type="entry name" value="DUF357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158372">
        <property type="entry name" value="SSF158372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF357" evidence="1">
        <location>
            <begin position="10"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="93" mass="9784" checksum="96CAF8A4E273CD7E" modified="2013-11-13" version="1">MGRLEEKTEKYERLLATAIEAASVPAGADDERAAGAETCLAMATAYLNDGQHFRAEDTPVEALAAFSYGHGWLDAGARLGVLAVPAEGDLFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8U0</accession>
    <name>U1P8U0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00702</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88556">
        <property type="protein sequence ID" value="ERG88556"/>
        <property type="gene ID" value="J07HX5_00702"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1581746_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="170" mass="18239" checksum="433BD928DCCB7EA8" modified="2013-11-13" version="1" fragment="single">MSLEDHAEELASDLGVDTAEVKAELETLDKYDVPIDEAKQTVRRRYDTPQETDDAVPTKEIDAIGANDGTVGTTAVVMTVGKRSIQYSGDTHVIQEGKLADETGQISFTDWSVSGALETGMTVRIANADTREWDGAPELNIGDQTTVEPVEETLSVPSEPGGEATLEELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8W6</accession>
    <name>U1P8W6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00727</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88581">
        <property type="protein sequence ID" value="ERG88581"/>
        <property type="gene ID" value="J07HX5_00727"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154322_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="24938" checksum="F42146FBB64CC4E6" modified="2013-11-13" version="1">MSESTFFRICYPEIRQYNMDPIFWLLDLDGTLVDVETAYIHETVTTVGDRLGVGFTQRETEALWYGFGTARRDLLADRGVSSERFWQVFHNAEDPAARADATRLYADAGATVPQLNGPVGLVTHCQADITGPVLGRLDIRDWFDAVVCCDSQTGWKPDATPVTKAVDELGVPARDRRRGVLVGDDPNDIGAAWNAGLTGVHVRRRAPDQVGGCVRSDRQITSLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Z4</accession>
    <name>U1P8Z4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="1">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00752</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88606">
        <property type="protein sequence ID" value="ERG88606"/>
        <property type="gene ID" value="J07HX5_00752"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="246" mass="26325" checksum="FFF16851B2DCF5BC" modified="2013-11-13" version="1" fragment="single">GPGAGPVGVREALAPFLPGPRVRQTTATITESATDGGLIREQQTESHTGTDEDGDRDRDTTPATGDASTTGTDDAGTTQPTYKLFTPEHTIGKVHGFEGNWLVLLKAHAYISRLGGAGLADASAKAVLNANYLAEQLDYEIPYGPFHHEFVASADRDASDVAKRMLDHGVHPPTTKWPELVDEALMTEPTETESRETLDQLAAAFNMVADEGTVTLANAPDRTATRRIDQVGAARAPRLSWHALDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P973</accession>
    <name>U1P973_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="7">FBPase class 1</shortName>
            <ecNumber evidence="7">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fbp</name>
        <name evidence="11" type="ORF">J07HX5_00832</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88686">
        <property type="protein sequence ID" value="ERG88686"/>
        <property type="gene ID" value="J07HX5_00832"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="10">
        <location>
            <begin position="163"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="288" mass="30414" checksum="C2CD6DCFD9D89FA8" modified="2013-11-13" version="1">MTVDRVFATVAEVTGDVQAGFTDRRHATGTNPTGDEQLRADVQADQLLADRLLALDLVASYTSEERPSVTASGTETGGQYHIACDPLDGSSNLASNNPAGTIIGVYDQRPPAPGTALLAAGYVLYGPVTTMVVAVDDGGGQTVTEYLLKNGERRVLDADVQLPETPTVYGLGGRVPDWPAPIVEYVDAIEADRLKLRYGGAMVADVNQVLAQGGVFGYPMLVDRPEGKLRAVFEALPMAYIMTAAGGAASDGTEPLLATAPDNLHERTPVFVGSEPLIERLEETLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9N6</accession>
    <name>U1P9N6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK-like ATP-grasp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00977</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88831">
        <property type="protein sequence ID" value="ERG88831"/>
        <property type="gene ID" value="J07HX5_00977"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2055974_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="50"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="119" mass="12747" checksum="FDE28DE7BCAC0BA6" modified="2013-11-13" version="1">MFYLQEYVAKPDRDVRVLAVDGEPVAAMTRTADHWLTNAAQGAETAPFALDSEAQALVRAASDAVGGGLLGVDLMETADGYTVHEVNHTVEFKALDQATDVDVSARVVDWLETRAEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9V3</accession>
    <name>U1P9V3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system, permease component II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01012</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88866">
        <property type="protein sequence ID" value="ERG88866"/>
        <property type="gene ID" value="J07HX5_01012"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="265" mass="28138" checksum="36CE7F8D20761CC3" modified="2013-11-13" version="1">MTVSFAARARSRFFQTTAVVTFLFLYLPVVTIVYLSFAPSSQPSIPLTEFSLEWYEAVFANTRFVRGLVTSTIIGAIAATVGTALGLIAARTIVRADLPGWVRGLVAVVVAVPLFVPTVVLALGIGITAGAVGIGYGFLPIVLGHLFWVLPFSTFLLTARYAELDDALEQAARDLGADDWTTFRTITLPLLGPALVASVLFTFALSFNEFLITFFLAGGGVTTMPLELFGKIRVSATSFLNAASVIVLLISAAVALVASLLRTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9X2</accession>
    <name>U1P9X2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01032</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88886">
        <property type="protein sequence ID" value="ERG88886"/>
        <property type="gene ID" value="J07HX5_01032"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2177795_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="12132" checksum="4E9D2131B862F36A" modified="2013-11-13" version="1">MPTALTLFSSDVGTFAPVPRLGSGSLPSALGVHRRATAAWSPTASHHPLSSRFLTRTHALVLLIWVCQRDFTNPQDTIAVCAIVYFTMRWHGCVNFRYSDESRLTERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9Z5</accession>
    <name>U1P9Z5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytidyltransferase-related domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01062</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88916">
        <property type="protein sequence ID" value="ERG88916"/>
        <property type="gene ID" value="J07HX5_01062"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3018542_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="56" mass="6307" checksum="CFEC25B4047BFD76" modified="2013-11-13" version="1" fragment="single">MKIALGGTFDPIHDGHRALFDRAFALGDVTVGLTNDELAPRTRDEDRPIRPYDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA02</accession>
    <name>U1PA02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01073</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88926">
        <property type="protein sequence ID" value="ERG88926"/>
        <property type="gene ID" value="J07HX5_01073"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="306" mass="32917" checksum="1FA7A62739AA27FA" modified="2013-11-13" version="1">MGIIETHALTKQYGDVVAVEELDLTVRAGEIYGFLGHNGAGKTTTINMLLDLVRPTGGTVRMFGEELDADSQTIRDRIGVLPAHAELYDRLTARKHIQFVDRVKDAGVDVDALLARVGIPDAADRPAGEFSTGMGQRLKLAMALVGEPELLILDEPTNGLDPNGARQMREIIQAENDRGATVFFSSHIMGQVDAMCDRVGVLNEGRLVAEDTVDGVREMATSGTELSVTVAGRADRVAEHVRPIDGVTSVVADHQTVRIALQSVDAKGAAMNAVAATDAQIRDFELREETLEDAFADLTQRTEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA07</accession>
    <name>U1PA07_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">GTP cyclohydrolase III</fullName>
            <ecNumber evidence="1 2">3.5.4.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gch3</name>
        <name evidence="4" type="ORF">J07HX5_01078</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:22468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57258"/>
            <dbReference type="EC" id="3.5.4.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the archaeal-type GTP cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.29" evidence="1 2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88931">
        <property type="protein sequence ID" value="ERG88931"/>
        <property type="gene ID" value="J07HX5_01078"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080076_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043740">
        <property type="term" value="F:GTP cyclohydrolase IIa activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00608">
        <property type="entry name" value="GTP_cyclohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007839">
        <property type="entry name" value="GTP_CycHdrlase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42202">
        <property type="entry name" value="PTHR42202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05165">
        <property type="entry name" value="GCH_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009265">
        <property type="entry name" value="GTP_cyclohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28910" checksum="B778D6315D1C9B62" modified="2013-11-13" version="1">MTTTQLTLIQIDNYGPWTVTPEPRREMDLQTLQSRLFADLAQFVGSRDGYVFFTRFDNMIAVTNGMGRDDHALLQESIDNRYPVTISLGVDINEQPIEALEDATQQIQQAGSAQDKGRTEVLGGDSWPETDSGPALDELEVAHFDVNDATGKYTDQLNEFDSYIQIERGYASVMQYMREEHGALSFFVGGDNVISVCPDLSESDYRGAIDYVRDDAEVDLKVGVGRGKSAHEAGYAAKHALEDCRHDGTRVEFAGAKLPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA44</accession>
    <name>U1PA44_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP cyclohydrolase MptA</fullName>
            <ecNumber evidence="3">3.5.4.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GTP cyclohydrolase IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mptA</name>
        <name evidence="5" type="ORF">J07HX5_01126</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25860"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58854"/>
            <dbReference type="EC" id="3.5.4.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; 5,6,7,8-tetrahydromethanopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase IV family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.39" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88976">
        <property type="protein sequence ID" value="ERG88976"/>
        <property type="gene ID" value="J07HX5_01126"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062816_1_0_2"/>
    <dbReference type="UniPathway" id="UPA00065"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003933">
        <property type="term" value="F:GTP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01527_A">
        <property type="entry name" value="GTP_cyclohydrol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003801">
        <property type="entry name" value="GTP_cyclohydrolase_FolE2/MptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022840">
        <property type="entry name" value="GTP_cyclohydrolase_MptA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36445">
        <property type="entry name" value="PTHR36445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02649">
        <property type="entry name" value="GCHY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00294">
        <property type="entry name" value="TIGR00294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="site" description="May be catalytically important" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="311" mass="34159" checksum="9144FDA77D890FC8" modified="2013-11-13" version="1">MSQQLPDVQATSPDVTVGLNRVGVTGVEKLVKLTRSNSRPIVLMAEFEVYVDLPDWRKGADMSRNMQVINETLEAAVNKPTYRVEDVCGNAAERLIEKHEYTTQAEVRMEAEYVQHEQTPESGLQTQATANIVASATAREDSTRQEIGVEVTGMTVCPCSQGMSESRARDALRGLEVDTATIDQFLEEVPQAGHSQRGHATLTIESVGVPEVDLTQLIEIARDAMSARIYNLAKRPDEDYMTYEAHSDAKFVEDCVRAMAEGVVEAFPELSDEAVVTMKQSNDESIHQHNAHAGRAAKLGQLRGEVSADPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA58</accession>
    <name>U1PA58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01141</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88991">
        <property type="protein sequence ID" value="ERG88991"/>
        <property type="gene ID" value="J07HX5_01141"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1744232_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="15386" checksum="0A3BBF483E13C8B5" modified="2013-11-13" version="1" fragment="single">MQSTTDRVFSAFSPHTGQSSAPGRRRRPSPAGQTVFAATLRREEPTTEIDAGESAAHSIGGAASTRRGCLVLEQSASSAVSGSEATSETTQTVLSRAGHEQESSVGAGANRIAATGISFGGPVIVLACSADQNNGTSWTVSRIKRPLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA74</accession>
    <name>U1PA74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Divalent cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01156</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89006">
        <property type="protein sequence ID" value="ERG89006"/>
        <property type="gene ID" value="J07HX5_01156"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111003_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="PTHR16228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="MgtE" evidence="7">
        <location>
            <begin position="51"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="191" mass="19914" checksum="0DC8D17CF2ED844B" modified="2013-11-13" version="1">MPTNAQAEFWSIYRQALPVLIISLGGGLFAGVVLDSLVDAVADVPGLLVMVPVFLATRGNVYGALGGRIASGLHQGLIEPSFSYDERLLNAVIASLVNGIGISVVIGGLTWGVLTLLGWGPAALGQLIMIMFIAGLLTSVVLIVGLLVVMFVGFNRGYDPDNLVGPIVTTIGDMFGTVFLLLSVRLSGVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAD9</accession>
    <name>U1PAD9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">V-type ATP synthase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">V-ATPase subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpD</name>
        <name evidence="9" type="ORF">J07HX5_01218</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89066">
        <property type="protein sequence ID" value="ERG89066"/>
        <property type="gene ID" value="J07HX5_01218"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069688_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00271">
        <property type="entry name" value="ATP_synth_D_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="PTHR11671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="203"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="26988" checksum="4C58066DED0110AA" modified="2013-11-13" version="1">MTEDVKPTRKNLMEIEDRIEFSERGHDTLEQKRDGLIMEFMDILDQAQEVRSGLEENYQEAQRAIDMARAMEGDVAVRGAASALKEHPEITSQSNNIMGVVVPQIESTKVRKDLQERGYGVLGTSARIDEAADAYEQLLESIILAAEIETAMKKLLDEIEKTKRRVNALEFKLLPELRENQEYIEQKLEEQEREEIFRMKKIKDKKEAAEAEQADTAAAETPADEGEGEGEETVTADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAQ1</accession>
    <name>U1PAQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01329</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89176">
        <property type="protein sequence ID" value="ERG89176"/>
        <property type="gene ID" value="J07HX5_01329"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1168544_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="1">
        <location>
            <begin position="53"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="234" mass="26101" checksum="DFF6407376AD1897" modified="2013-11-13" version="1">MPKTEYDGTINWDQYWETASDPVDDDANGSLQRLVEPLCEFIDERGVPDSHADVGCGGGGLAFTVADRHPDTTVVGYDAAEPVVAQNRRRAAEDEYPAVQFKQTVLPEFAPDRQFELVTAFFTLCYVPAVETALQALYDAVTPGGHLLMTYHNRYAQSLFASYAQNPEAHFGPDSVFAPESFADRFELVIEGESLLSYDQIHGTLGAWPQSVWSVARTERYDAWRQNPLVFVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB67</accession>
    <name>U1PB67_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="7" type="ORF">J07HX5_01479</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89321">
        <property type="protein sequence ID" value="ERG89321"/>
        <property type="gene ID" value="J07HX5_01479"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="6">
        <location>
            <begin position="190"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="156"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="219"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="298"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="425" mass="45942" checksum="8BEEC51DCBA4ED9F" modified="2013-11-13" version="1">MIAPISEQVSAVDDLQVDGERKMEWARQQMPILGALREEFTNDQPFAGERIGMAMHVEAKTAVLAELLAVGGAEVAITGCNPLSTHDDVSVALDSVPGVTSYARRGVDGEEYYDAMEAVIDHEPTITIDDGGDLVFAIHEEHPELIDGIIGGCEETTTGVHRLRAMDEDGALEYPMFAVNDTPMKRLFDNVHGTGEAALSSIAMTTNMAWAGSTVVVAGYGDCGRGVAQKAAGQNAEVIVTEVDPRRAVEAHMEGYDVMPMAEAAEKGDFFITTTGNRDIIVDKHFERMADGTVLANAGHFDVEIDLDALSDLAVDTYEARDGLQAYEMSDGRRLHVLAEGRLVNLASPVSMGHPIEVMDQSFGIQAVSARELVESADAYDPGVHTVPDRLDREVAETKLAAEGVAFDELTNTQREYMESWQHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBC6</accession>
    <name>U1PBC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative membrane protein (DUF2078)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01519</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89361">
        <property type="protein sequence ID" value="ERG89361"/>
        <property type="gene ID" value="J07HX5_01519"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137730_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="3">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="15549" checksum="641C972E48F5349F" modified="2013-11-13" version="1">MSDPVRRTGENLPEIVAVSITGVWLTALFTGQDWWLPLMIFGYIVIVPITELLFGDQEETEERWDEAEDISAPEESSAEDPLERLRERYVQDELTDEEFERKLERLLETESIEDVQAQNQHNRDRLDQELER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBH8</accession>
    <name>U1PBH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01584</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89426">
        <property type="protein sequence ID" value="ERG89426"/>
        <property type="gene ID" value="J07HX5_01584"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3338305_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="37" mass="4011" checksum="0FAC7BD5F399D61D" modified="2013-11-13" version="1">MSTPFQSDTADTTTAADQHSADSDDDPTPGEDRPPWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBL8</accession>
    <name>U1PBL8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin-dependent thymidylate synthase</fullName>
            <shortName evidence="1">FDTS</shortName>
            <ecNumber evidence="1">2.1.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">FAD-dependent thymidylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Thymidylate synthase ThyX</fullName>
            <shortName evidence="1">TS</shortName>
            <shortName evidence="1">TSase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thyX</name>
        <name evidence="3" type="ORF">J07HX5_01625</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP + H(+) + NADPH = (6S)-5,6,7,8-tetrahydrofolate + dTMP + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:29043"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.148"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="1">Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate synthase ThyX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.148" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89466">
        <property type="protein sequence ID" value="ERG89466"/>
        <property type="gene ID" value="J07HX5_01625"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077585_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01408">
        <property type="entry name" value="ThyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02170">
        <property type="entry name" value="thyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Involved in ionization of N3 of dUMP, leading to its activation" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="192"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <note>ligand shared between neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="27999" checksum="341E00B5087433C6" modified="2013-11-13" version="1">MQVELLEATGDPERLICQAARNDYMEEFVADTPFDKMMRNIGGETLQAKQETLIRRLLDHGHFGPFEHPHASFAVKGISRSCLAQVTRHRHATFDVQSMRYVAFDDVDPADVHEGEMVVVPPSAGDPDWVGRNQQSGPVDDETAQRREELFRETVADAFAAYQELLELGMPPEDARFVLPIGTKVNMVMTVNARMLMHIADMRAAADAQWEIREMTEQILDLAADWCPITFEHYEADMKGRKNRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC72</accession>
    <name>U1PC72_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIB</fullName>
            <shortName evidence="7">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tfb</name>
        <name evidence="11" type="ORF">J07HX5_01863</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TFIIB family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="J07HX5_01863"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:transcription preinitiation complex assembly"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
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        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="11" id="KW-0396">Initiation factor</keyword>
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    <keyword evidence="2 7" id="KW-0677">Repeat</keyword>
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    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="10">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="1" evidence="7">
        <location>
            <begin position="144"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="7">
        <location>
            <begin position="238"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
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        <location>
            <position position="53"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="36680" checksum="89A6E2CB19350CC7" modified="2013-11-13" version="1">MTDTTTRRYARETEKEQEEENETTEADEELVCPECAGNLIVDDERGETVCADCGLVVSEDEIDPGPEWRAFDAREKDEKSRVGAPTTKMMHDKGLSTNIGWQDKDAYGNALSSRQREKMQRLRTWNERFRTRDSKERNLKQALGEIDRMASALGLPENVRETASVIYRRALDENLLPGRSIEGVSTAALYAAARKAGTPRSLDELTRVSRVDKDEIARTYRYVVRELNLEIKPADPESYVPRFASDLQLSEEVERRARSLLSTAKEQGVHSGKSPVGLAAAAVYAASLLTNEKVTQSEVSEVANISEVTIRNRYHELLEAEENVPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCH6</accession>
    <name>U1PCH6_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01968</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89796.1"/>
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    </dbReference>
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            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89796.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6181" checksum="F448E594E6666E0E" modified="2013-11-13" version="1" fragment="single">NTNGNVLAIPYHDDERPWMQNHEQRDWALEIPAYSSDENARNNPPTVADASTNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PD06</accession>
    <name>U1PD06_9EURY</name>
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        <recommendedName>
            <fullName evidence="2">BFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02149</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="165" mass="17768" checksum="687AE2E8EB6B6D4A" modified="2013-11-13" version="1">MEHEATVKGVGASTNDEGRGAPVVIVEARSEFIPIFISPDQAQSMQLALEGEPFERPLTHDLFVEMVAEFGAAIDRVRIDDLADGTFYAKIDAEQYLDGERKQAVFDARPSDGIALALRVDCPLIMSNAVIDEAGRPREAFDTSDDDTDTDTDTGSGSGPTFGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFM8</accession>
    <name>U1MFM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type branched-chain amino acid transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00085</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG87944"/>
        <property type="gene ID" value="J07HX5_00085"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
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        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="49"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="409" mass="44273" checksum="2B77139C72E9A2D9" modified="2013-11-13" version="1">MSNQQYDAAADSETADRGLSRRQFIGTVGGSVIAGAAGCLGSSNSNAFKIGAALSLSTQGWETYGNTMLRAVRIAADQMQERGVFGDREVSVITEDTQVDPQTTRNKVEKLTTQDDVDVVVGPVSSANRIPAAELFRENQTPGLYAVEYEGAVAEDYCNPWLFKSAEVPEQQVEPFVPWLVDEYGSSFYLLGSDYTWPNEMNGQIQTVLENQGGEVVGEEYAALGETDFSSIIPRIENADPDVLFMTLTGASVPAIQEQMLNFDVRGQWTDVGISHGQGLLQGAPAEAVEDVVSCHSYMESLETDRNQQFVQAFRDRGTDVPITFLTGTTRVAMRLLEQAIETEGDASADGIQAGLRGVSAKTVVGEVAIETDQQATLPTYASRVNGERQHVPVESFDAVQPDPQCDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFQ4</accession>
    <name>U1MFQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00125</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
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        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="155"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="27654" checksum="0ADAAE54608CB42D" modified="2013-11-13" version="1">MRESRLFERDGTWYLHVTATRNVEVGSEVSAEERTLIGVDIGEASLVMVCHRDNDGFPTAPELWADEGKIVRRLHEIYFTATRRLQTRGSKRIAESFGDDLWNQIDDVFHRVTREVVEYTESVENPVLDLEDLTYIRESMDYGEYMNRRLHGWGFAKLRAQIRYKAVEKAIPVETVSPRNTSKECHACSEVGYRPKQATFNCTNDACWMGEYQADGERRRPLPQRRELFQRTRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFV5</accession>
    <name>U1MFV5_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Transcriptional regulator, contains sigma factor-related N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00190</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88049">
        <property type="protein sequence ID" value="ERG88049"/>
        <property type="gene ID" value="J07HX5_00190"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176006_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9501" checksum="48AB1AED0C289F97" modified="2013-11-13" version="1">MTNSDGEGVEDLPPSAKLVYKVLEYSGPLTQKGIAEESMLSARTVRYALERLKRIGVVTEDVYFADARQNLYEIETTDVEPVMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG20</accession>
    <name>U1MG20_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA double-strand break repair protein Mre11</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mre11</name>
        <name evidence="8" type="ORF">J07HX5_00277</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Nuclease activity is regulated by Rad50.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
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        <property type="protein sequence ID" value="ERG88134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88134">
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        <property type="gene ID" value="J07HX5_00277"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026621_3_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045027">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02044">
        <property type="entry name" value="Mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032885">
        <property type="entry name" value="Mre11_archaea-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="12"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="535" mass="57201" checksum="2CDE07EC5BBE45EB" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGF9</accession>
    <name>U1MGF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00442</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00442"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135994_0_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF371"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023131">
        <property type="entry name" value="Mth639-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40696">
        <property type="entry name" value="PTHR40696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04027">
        <property type="entry name" value="DUF371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="15045" checksum="375C94FB0A7909A1" modified="2013-11-13" version="1">MVTLSDATHTEVVHARGHENVTATHESTFELTTDEFLTPAGDCILGIEADRAPAAFDEAFIAACRDPTAEIMAVLEVDGRTTRVTASGASGLSLTSDRSLVVRTSDYVDARTVAVGATAAAADIDRGIVDALAAGAELTLTLGISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGP8</accession>
    <name>U1MGP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00523</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88379">
        <property type="protein sequence ID" value="ERG88379"/>
        <property type="gene ID" value="J07HX5_00523"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_15_12_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="30809" checksum="699C936FC289784E" modified="2013-11-13" version="1">MYTLNAGVEVNPDSYAPFATSGSTGVITAAAFVFVSFAGVTKIASIAEEVENPGKNLPRAILGSMAIMTLVYIAVVAAIVGLADAETLKHGGPNDGASLTPMADGAEALFGGAGVLIISVIAVVALTSMANAGVLSTSRFPLAMSRDNLLPSQLETIDERFGTPRNSVLLTGAVLLSLIAFVPVIELAKLASAFKILVFSIANVALIAFREADVPSYDPEWTTPGYPYVQVFGLVAGIGLLTQMGRLPILGAGGIIVGSIVIYLVYGRPRTDRSGAIGTIIHDRRGQADDGLTPTDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGR4</accession>
    <name>U1MGR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00549</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88404">
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        <property type="gene ID" value="J07HX5_00549"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4149" checksum="3E1136D07379D236" modified="2013-11-13" version="1" fragment="single">MRNKSSPSDGASNIDTSGERAAKAGELLGMRQLLTSELVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGT0</accession>
    <name>U1MGT0_9EURY</name>
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        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00574</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00574"/>
    </dbReference>
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        <property type="term" value="F:nucleotide binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cellular amino acid metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
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        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
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        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
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        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="182"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="7">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="416" mass="44230" checksum="194BF23D353C068B" modified="2013-11-13" version="1">MSDVDPAESLRTQIETAARHIDVSSGQLDRLKAPERVLTANIAVQRDDGSTEVVRAYRSQFNGARGPYKGGIRYHPAVTRAEVTALSGWMAFKTALCDLPLGGAKGGVAIDPEAYSERELERITRAFAAELVPLIGADSDVPAPDVNTGQREMGWLRDTYETVVQTTAPGVVTGKAVPNGGSQGRQSATGRSTVLTAVRALEYLGKDLAGATVAVQGYGNVGSTAARLIDARGADVVAVSDSTGGVYDQSGFDPGAVKQHKRDTGSVVGAPGADRSVSSETLLTLDVDLLVPAALENAIDEQLARELSADLVVEGANGPITPAADAVFRQTETLVVPDILANAGGVIISYLEWVQNRQRQSWSKRRVNETLATTINEQFTTLIETYETTTLDSLRTAAYVIALRRILAATNQRPWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGV9</accession>
    <name>U1MGV9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00619</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88474">
        <property type="protein sequence ID" value="ERG88474"/>
        <property type="gene ID" value="J07HX5_00619"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1387561_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="21991" checksum="BA09F2F6EF8FD789" modified="2013-11-13" version="1">MLEYPCPDCFTSTVLHTADCRFEGVDRDAVERAYVDILSTVLGTPADKALTKAGLKQRLSDQWGPLHEAALGRLTAHYYLRETDNGLEPVTAATRLNEQEPTAPALRTLWEHGSVPGCHDNAIFALISWHELHGFDWEQTCERMIEWFDRTGTWARGGFDEPSPATVLANKRHVHEEGYGWRDKAEMAAGVVERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH51</accession>
    <name>U1MH51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Periplasmic serine proteases (ClpP class)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00760</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88614">
        <property type="protein sequence ID" value="ERG88614"/>
        <property type="gene ID" value="J07HX5_00760"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076515_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="3">
        <location>
            <begin position="113"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="3">
        <location>
            <begin position="185"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="34924" checksum="DC684503984DBE80" modified="2013-11-13" version="1">MPDEEPSADTSAADQTESPTSRRVFIAVIAVAIVAIAGVVAFGLISSGGGGTADSAVAVVSVEGQITGDTAENLETELRDLRGNDDVKAVVLKMDTPGGLVQPSERMYTAVKRLSAEMPVVASVQAISASGGYWTMLPADQVYVSATSIVGSVGVNAPAPSPAAPVEGPTGPDKVGSTITGRWATIDTLQQLFVTSVFEERGDTIELSREEVATASVWRGIEAVENGLADEIGLLDAAIQDAAASADLDEYRIIERSTAPQGLFLLLSAEGLVTVEGENPALNDVSPVEMSVIYEPWVPSIENAQSVVAASSPSRSGAADATAANETTAETDTDTDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHB2</accession>
    <name>U1MHB2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00845</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88699">
        <property type="protein sequence ID" value="ERG88699"/>
        <property type="gene ID" value="J07HX5_00845"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2140124_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_11" evidence="1">
        <location>
            <begin position="10"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="11612" checksum="75435F5642D8EC70" modified="2013-11-13" version="1">MSGTVSGTDDSASVVAATTASCGSRIVQTQSFDTAVVDEAGQFTEPGTLAAAVLADRLVLAGDHQQLPPVVRSKSDAPSETDAAPVADLSRLLFERLIDAHPEAAVRLTEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHS5</accession>
    <name>U1MHS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type spermidine/putrescine transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01010</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88864">
        <property type="protein sequence ID" value="ERG88864"/>
        <property type="gene ID" value="J07HX5_01010"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="13"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="402" mass="42626" checksum="E2E5B6EA30519D14" modified="2013-11-13" version="1">MTDLGAGNANVILEANEIRKEFSDTVAVEGLSLSVKRGEFFSLVGPSGCGKTTTLRMLAGLTTPTSGTVQLNGINVTDRPARKRDTNLVFQDLVLFPHMSVAENVGYGLARQGVPAPKRSRRVSSLLETVDLGGLGDRQPTELSGGQRQRVALARGLAPEPSVLLLDEPLSSLDRKLRQEMQAELRRVQRDVGTTFLYVTHDQDAAMSMSDRVAVMNDGQIVESGAPEALYDRPATAFVADFLGDANILAGTVTSVANDTTTVAIGTGTVQAAPGSQAPAVEDSVAVMVRPEDLTLGDGPLSATVQASEFKGFYDKYTLALSTDETGVITARTNANKQFETGDVINLSITNATMVALNGEAMTIDELRRSAVSVGTQPDAPGGVGDRQHMDSDKQTARTQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHU7</accession>
    <name>U1MHU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phosphohydrolase (DHH superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01040</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88894">
        <property type="protein sequence ID" value="ERG88894"/>
        <property type="gene ID" value="J07HX5_01040"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055955_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="356" mass="38665" checksum="7DBE7BE5ABFCD558" modified="2013-11-13" version="1">MDDSLIDTDQLSIERKSMLPGAGFFRSDTVSDEQTQQKVRSRLAGAETVVIADSDADGLGCVALVRTAHDNVAFLPASPHKLRDQIAHAADCVEPGATVYLCDLCPDHADDLEALTDLVDRAGQVAWYDHHEWTPALADSVRETGVALTVGDSDAVCSADVTRDQLSASFPDRLEELVVVTRDHDLWIREDDRSDDLADYAHWAEPETYIETVIEHGPALPADAQDLLAERRVEKQALIDRAVERATFREVGPWTVGITYGRCSQNEVAERLRTDGADAAVIVKPAGSASIRGTDAFSRCHDVAAQVNGGGHPKAAGCKPAIYDDMLDYAHHWTTEGAVAKRVILAAFQQITPESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI24</accession>
    <name>U1MI24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01149</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88999">
        <property type="protein sequence ID" value="ERG88999"/>
        <property type="gene ID" value="J07HX5_01149"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="245" mass="26206" checksum="1BC268C613612F5E" modified="2013-11-13" version="1">MTSAPDLEGRTALVTGSATRVGRELLLRIAACGADVVVHYRTSEAEAAATAEQARDHGVAATTVQGDITVPAEVDALFSTAEADLDSVDILVNNVGNFDPRHWEAIEWEAWRSVVESTFYGTVLCSRRALGGMRSQEWGRIINIGFADSDQLHAPPVNFPYFVAKTGVLMFTRMLAGDTQEDGITVNAVSPFAVENTVSDVSAFPRGRAASFDDVAAPMLFFLSEEAAYISGENVAVDGGRLTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI74</accession>
    <name>U1MI74_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing] subunit A</fullName>
            <ecNumber evidence="3">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">guaAA</name>
        <name evidence="5" type="ORF">J07HX5_01221</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89069">
        <property type="protein sequence ID" value="ERG89069"/>
        <property type="gene ID" value="J07HX5_01221"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_4_2"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01510">
        <property type="entry name" value="GMP_synthase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023686">
        <property type="entry name" value="GMP_synthase_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="1 3" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="184" mass="19572" checksum="7578431EC8A64EF0" modified="2013-11-13" version="1">MTRIDVIDNHGQFTHLEQRALSDLGVETDILANDTPPEEIDADGLVLSGGPDIDRTGNAGEYLELALPVLGICLGMQLIARELGGAVSAGDYGGYADVTVEVTDTDDPLVGSLAPETRVWASHADEVTTLPAGFVQTARSKVCGIEAMSDPARGLYGVQWHPEVAHTEQGQAVFENFRAICEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIJ8</accession>
    <name>U1MIJ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01389</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89234">
        <property type="protein sequence ID" value="ERG89234"/>
        <property type="gene ID" value="J07HX5_01389"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1656846_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043811">
        <property type="entry name" value="DUF5793"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19106">
        <property type="entry name" value="DUF5793"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="160" mass="17481" checksum="165DDCD654CBC15C" modified="2013-11-13" version="1">MRRDNFTATIDTVSDDPMLRIEYDGPTDDLGRRLTDPADELYTAADVDAAFRLTEPVEASDAAGVFSLSHRVTGEFLLEANTTADRVFDLIAAARDADDGSSYQITIDTAELGLTSADTDTEADDEDRTRVVHELHALFVYDASGELLRQHSLIPSGVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIK9</accession>
    <name>U1MIK9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="5">HMG-CoA reductase</shortName>
            <ecNumber evidence="5">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01405</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-mevalonate + CoA + 2 NADP(+) = (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89249">
        <property type="protein sequence ID" value="ERG89249"/>
        <property type="gene ID" value="J07HX5_01405"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001734_2_2_2"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="PTHR10572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="SSF55035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="SSF56542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="407" mass="41159" checksum="518A63BBAAAC8F33" modified="2013-11-13" version="1">MPAADPTAADLAARVRDGELRLYELEEHTDAETAAAARRRVVTAETEADLEAVADYTFAAATAEPNIENLLGAVQIPLGVAGPVPVDGGAADGEFYLPLATTEGALVASVNRGLSTIAAADGATARVTNAGMTRAPVFRVAGVAEAATVNEWVAANTDRLREAAESTTNHGELLEVDPYVVGDNVYLRFVYDTKDAMGMNMATIATREAATLVEADTPAELVALSGNLCADKKPAAINAVEGRGRTVTADVVIDGDLLVEQLAATPAAMAEGNVRKNLVGSAKAGSLGFNAQAANVVAAAFLATGQDEAQVVEGANAITTMEVRDGDLYASVSLASLEVGTVGGGTGLPTQTAGLEILGLGGGGTPPGANADALAEVIAVGALAGELSLVGAFCSRHLASAHERLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ02</accession>
    <name>U1MJ02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01562</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89404">
        <property type="protein sequence ID" value="ERG89404"/>
        <property type="gene ID" value="J07HX5_01562"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2255616_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="1">
        <location>
            <begin position="23"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11845" checksum="A9CCAAD447F3B5BE" modified="2013-11-13" version="1" fragment="single">MSSIEISNQHPATHPELGWALLYEQNVEEIKTVDGLWLGIDLGVDNLATCCDWRGYLFTVDGRHLKSLNRCHNRKIAHHQSKTSKGSTTRLNVSRSCIRNVDTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ78</accession>
    <name>U1MJ78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type transport system involved in multi-copper enzyme maturation, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01679</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89514">
        <property type="protein sequence ID" value="ERG89514"/>
        <property type="gene ID" value="J07HX5_01679"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071765_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="28308" checksum="0B3267444E1291D9" modified="2013-11-13" version="1">MGSVNWRGLARKDFRDAVRSRSVVVLLAGFLLLYLLIGYAGVELVGDDFDAVVSLAGLATAFVLPIVSLGVGYKSIIAARSSGAIALALSLPHSRLDLAVGTFVGRAGVVLLPAVAGLTVAAAVAGVLTGPPPVAYLGLVAVTVLYGLAFLGIAVGVSMGVGTSRRATGGAFGAYILFVALYDQLIQLLVFVLFRFQSVGLPDWARLAQHLGPPQAYSYVVSELFGDVSVVTQFTTTAPPGWFTAPVAVLVLAGWVGLSLAVGYRRFRRAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJC9</accession>
    <name>U1MJC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylaspartate mutase, S subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01745</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylamine corrinoid protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89579">
        <property type="protein sequence ID" value="ERG89579"/>
        <property type="gene ID" value="J07HX5_01745"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136705_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016866">
        <property type="term" value="F:intramolecular transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019670">
        <property type="term" value="P:anaerobic glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006394">
        <property type="entry name" value="GlmS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01501">
        <property type="entry name" value="MthylAspMutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="21"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="165" mass="17634" checksum="BEE28E9307E5E44C" modified="2013-11-13" version="1">MQSSTPLLSIGKGVTDKQMSSPSVVVGTIGSDAHVVGITLLEHALREAGFEVRNLGAQTPKKAFAEAAAEIDASAVLVSSLYGHAEQDCAGLHEELAARDVAPTTYIGGNLAVGQSEFEEVRRRFREMGFDDVFDADTDFEDVVTALRAEFGMDERTTQVAQARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJI3</accession>
    <name>U1MJI3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cob_adeno_trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01814</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89644">
        <property type="protein sequence ID" value="ERG89644"/>
        <property type="gene ID" value="J07HX5_01814"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083486_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="4">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="101" mass="11098" checksum="DD7C1CB56CEC6D72" modified="2013-11-13" version="1" fragment="single">SDPAMTEAHVTGLEATIDTFDAELETLEEFILPGGSTPGARLHHARSVCRRAERRAVAFAGEEENANDAAIVYLNRLSDALFTLARVLNKREDVPEENPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJR1</accession>
    <name>U1MJR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01906</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89734">
        <property type="protein sequence ID" value="ERG89734"/>
        <property type="gene ID" value="J07HX5_01906"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3225880_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="44" mass="4723" checksum="03D0AD43C133E384" modified="2013-11-13" version="1" fragment="single">GWGFETTAEQGVAAPPNWLLILATRTVADHRGESGRTDVRAVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJZ4</accession>
    <name>U1MJZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02001</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89829">
        <property type="protein sequence ID" value="ERG89829"/>
        <property type="gene ID" value="J07HX5_02001"/>
    </dbReference>
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        </source>
    </evidence>
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</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89834.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="580" mass="63095" checksum="384212474D6A8F0C" modified="2013-11-13" version="1"> </sequence>
</entry>
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        </source>
    </evidence>
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        <source>
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        </source>
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    <sequence length="223" mass="24243" checksum="72CCC2A87A01EA2D" modified="2013-11-13" version="1">MTCPPAARNRXXXXXXXQGGDGVDGIGCPVEGLDERLCLLFIDVEDSREIGIGNSSCVYCSCDFGTDGPAANKTNIKLHMQCHIYSVFVLDEFVATEPCYLTGLRRGCWGMQGTPPTDNRSVAFLQVTSLSTRRGVQRCGRDGQNKRGPRRGASEDGLDEMVRPVASGRPDGRILIELLADKHWRAILIKETALADRLDPSAVGRGSSQCGVRHVSFGYYLVA</sequence>
</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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    </feature>
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        <source>
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        <source>
            <dbReference type="EMBL" id="ERG88025.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="296" mass="34114" checksum="5700255BC299302E" modified="2013-11-13" version="1">MEVRRTAVVKLDLSDEQRDALHRTAEQYLYCANRTADYCWSDTSYTECRTNKREVRDALYADLREETDLQAQLVQAAIKRAVEAVKACVERWKKGQRVSRPTFTAETMDYDTRSATFYRNKVSLATVEGRVEPPFVLPADSPTPYERYILSEDYEFRESTGRYDAVDDEFYIQLSTRRIDGDAEVSADAGHPDQTVLGIDLGVNSLAVSSTGTFWQGDDYDHWCHEFEKRRSEMQQRGTQAAHNALLRLGKREEAWRKQYIHTVANELVTEAVEHDCDVIAFEDLTDIRDRLPQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVE4</accession>
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        <submittedName>
            <fullName evidence="3">Putative ATPase</fullName>
        </submittedName>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </location>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="47"/>
        </location>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88080.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
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    <accession>U1MVI2</accession>
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    </reference>
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            <dbReference type="EMBL" id="ERG88120.1"/>
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    </evidence>
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        <source>
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    <sequence length="51" mass="5613" checksum="F8188FFB4F7F5308" modified="2013-11-13" version="1">MGYLTTPHIASASQDVIDRYTKLTVNDLEALLNGEWPMQAANSETLDGFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVJ7</accession>
    <name>U1MVJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase involved in DNA repair</fullName>
        </submittedName>
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        <name evidence="8" type="ORF">J07HX5_00278</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88135">
        <property type="protein sequence ID" value="ERG88135"/>
        <property type="gene ID" value="J07HX5_00278"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004785_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013134">
        <property type="entry name" value="Zn_hook_RAD50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51131">
        <property type="entry name" value="ZN_HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc-hook" evidence="7">
        <location>
            <begin position="408"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="595"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="489"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="721" mass="80923" checksum="C7AE50EB2E1C65A9" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVL3</accession>
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        <recommendedName>
            <fullName evidence="8">Putative nickel-responsive regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_00298</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 8">Transcriptional regulator.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="8">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
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        <property type="protein sequence ID" value="ERG88155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88155">
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        <property type="gene ID" value="J07HX5_00298"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RHH_1" evidence="9">
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            <begin position="4"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="NikR_C" evidence="10">
        <location>
            <begin position="54"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
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        <location>
            <position position="88"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
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        <location>
            <position position="90"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
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        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
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        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="139" mass="15745" checksum="D850495ED35C71AA" modified="2013-11-13" version="1">MTVVSVSMPDELLERLDTFADEHGYTGRSEVVREASRNLLGEFEDERLEERELMGVVTVLFDFQETDVESRMMGLRHDHEALVTSHVHNHVGNHNCMELFVLEGSLEEISTVVGKIRAVQNTLSVDYSVTPVDRIDTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVM2</accession>
    <name>U1MVM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00159</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88018">
        <property type="protein sequence ID" value="ERG88018"/>
        <property type="gene ID" value="J07HX5_00159"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2820647_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="6934" checksum="ECCC471440ECE2D5" modified="2013-11-13" version="1">MGIPAGYDPAGVRLRAQNSPVVQSAIAQPLTLPWDCRRLLTVREIVALLAQACGRAHGGSALQLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVM9</accession>
    <name>U1MVM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00313</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88170">
        <property type="protein sequence ID" value="ERG88170"/>
        <property type="gene ID" value="J07HX5_00313"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447547_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9712" checksum="CEEADE8F995D5FC3" modified="2013-11-13" version="1">MVSFYLYYELIRLTASRHAPGKPPAPTGETPETSVMTALAADQPQHTRDTSPVSTVLPSDGRFRGTTMPDRRWRARLCVLAATGGQPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVQ2</accession>
    <name>U1MVQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00338</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="38" mass="4259" checksum="159BE276C7B845A8" modified="2013-11-13" version="1">MTRLILRSQESTAIRNNTETDDQHDIVSRSDGHTAGMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVX2</accession>
    <name>U1MVX2_9EURY</name>
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        <submittedName>
            <fullName evidence="9">Na+/H+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00413</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="8">
        <location>
            <begin position="92"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="453" mass="47948" checksum="8CD592683FC3F5DF" modified="2013-11-13" version="1">MTGTTAPPVTGVYLTPAARITEECSRRVTPWSHSMVQKEPEPTTERRNHNSQAXXXXXXXMRDITGSVQVSREKLSYLVDSTAAPAATLTFSSWVAFELSMIDEGYETAGVPDAETPAPISVFLGSVPYNMYAILAIVMVGVIVLSQRDYGEMFTAEQRAVETGRLSRDDADPMQDIASNLGEPCAERPRLSSFVSPILALSVGVVLTALWTGGAFRGTTLEETVRNADYAFAMLVGSLTMVGTTFLLGDAHGVLSLRESLATTVNGFRMMLTAVSILILAWAIGEAVSTLGTGEYVASLVRGTLTPEVLPVVVFATAGFISLTTGSSWGTMLILTPIVIPVTLDLAGTHEMVSVVVGMVLSGAVFGDHCSPISDTSVLSATFTGADLIDHVRTQLYYAGTVGLVVAVLMLVWGYTGVSPVLLLVTGSATLVGLVYGLSELQARLQGAPLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW19</accession>
    <name>U1MW19_9EURY</name>
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            <fullName evidence="2">Putative hydrolase or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_00321</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88178">
        <property type="protein sequence ID" value="ERG88178"/>
        <property type="gene ID" value="J07HX5_00321"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="30"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="265" mass="29502" checksum="FD685CA252676107" modified="2013-11-13" version="1">MKIPKQWEVGTVQSNDVDLRYYRAGKGQPIVLAHGFYESAQCRKPIIQNLAEEYEIIAYDARGHGYSDAPKQGYDIEQRVSDLHNISTGLGLEDPILFGHSMGAVTVAWSAAHHPELPKGVVLEDPVGLVQSETPSISPEERVAAVEQKLSKIDEQTVEQLAADHTEYEESVSRRIAHANKRCSKEVAEIAREQSPPVTNALSKIDYPVLIINSDDNPESKAKQLNAVEEFKHTRLVHIPEAGHAVFRGEFEAAYSELSTFLHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW42</accession>
    <name>U1MW42_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00484</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88340">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
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        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
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        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="156" mass="16602" checksum="4D71CB336F99AD9F" modified="2013-11-13" version="1">MAGVSVSVLGPPDVALAGGDPNENSLVVQVRHGATSFLFTGDAEQAGERFLVEEYGDMLRTTVLRAGHHGSATSTGDALLSVTQPRAAVLSAPYNSQYGHPHEETLRRLADRAVPSYWTTTHGSSVFASSGTHVTAQSHSRRRPIEAPARSPNRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW73</accession>
    <name>U1MW73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00499</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88355">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_17_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23524" checksum="D8AD9869A7979C74" modified="2013-11-13" version="1">MTRTVVIGGVGPTLGESLAREFATEGDNVALWARSTTVTADLAERLSADTPGSAIAVQTDVTDTNAVATAVDQVHKAFGPVDVYIHNVHSDTAWTGPLTDDPGDLATYFETTGYGLAVVVDVLLEDLFSTDGTVIYHTTDDLRWISRAMAEQPASEGVHVARTVIDGEIDGPAAPASLSAAERVDPDALTAECRRLVEQDRSVWSSDVDFRPWGDDSFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWA2</accession>
    <name>U1MWA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00530</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88385.1"/>
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        <property type="gene ID" value="J07HX5_00530"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="134" mass="14665" checksum="B142D259AF20B99B" modified="2013-11-13" version="1">MNTEKSRIVREELWRSVVWLLLGFVGWSILIDEVAWLDPNLFTALGLPAVTWAVLTAGMIGIRTVSGAELQSQVSASKFVLSSVVLIILTAAYLIRIQGYSPLLVIGGEITATTAAGVWYWYTGVFDQSTKQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWJ4</accession>
    <name>U1MWJ4_9EURY</name>
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        <submittedName>
            <fullName evidence="5">6-pyruvoyl-tetrahydropterin synthase</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">J07HX5_00651</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="14019" checksum="ACB0F93A1151230D" modified="2013-11-13" version="1">MYTVTVTREFIAQHWLTVPDPGPEGELHSHQFMAELTIEGPALNEFGYLVDIDRVNEVLDELETRYCDATLNNLGEFEGLNPSVERLATQFVDRVVPVLPADRLDQVTVKIWEDETAAASCVTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWM1</accession>
    <name>U1MWM1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal peptidase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00686</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88540">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027245">
        <property type="entry name" value="Sec11"/>
    </dbReference>
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        <property type="entry name" value="PTHR10806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="PTHR10806:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="281" mass="29719" checksum="3DEA858FF8535C03" modified="2013-11-13" version="1">MPTPDDETTSLGKDPSGTADQADGSTAEPTDADETRTLSDPGTADRSQPPAGDEADDRPNETAADAHGSEPQSDSVSAWRTPTNRANSSWVLLGRDIATSLLLVALVGAYLFAVSGVWPPMVAVESGSMDPNMEKNDLVFVMDTDRFQPDAAIDGTGVVVARDAAGTGYTQFNNPGDVIVFEPNGNEETTPIIHRAMFFVESGDNWVARANSAFLSSGVDSCSDVRSCPAPHDGFITKGDNNAVYDQTSGGQRSQPVRPDWVVGTAEIRIPGAGWLRLQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWX5</accession>
    <name>U1MWX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylyl cyclase CyaB, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00623</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88478">
        <property type="protein sequence ID" value="ERG88478"/>
        <property type="gene ID" value="J07HX5_00623"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105244_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07890">
        <property type="entry name" value="CYTH-like_AC_IV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008173">
        <property type="entry name" value="Adenylyl_cyclase_CyaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21028">
        <property type="entry name" value="PTHR21028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00318">
        <property type="entry name" value="cyaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="21204" checksum="858F09D0BC758645" modified="2013-11-13" version="1">MYEVELKLQTAHEPVRDQLGTTDATHVGRITQADTYYQAPDRDFADTDEALRIRIETPGDTAPESLSARTSDARVLLTYKGPLIDPESKSRAEAETPVADATALERILTGLGYEPTATVHKRRDRYRVEECAVVLDRVEGLGEYVEVETETDADVETARERAVAVLEQLGLDPADQIRTSYLGQLLAARDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXC0</accession>
    <name>U1MXC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00936</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88790">
        <property type="protein sequence ID" value="ERG88790"/>
        <property type="gene ID" value="J07HX5_00936"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629558_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8496" checksum="BFDAB4F23CC65A26" modified="2013-11-13" version="1">MSVTVYLDAAVDGDHELECTAATILRDVVRLMPRDTDQERVVPLDNVTGIDGDEVTHEIEEIEFPGGRATELVTRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXD8</accession>
    <name>U1MXD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00956</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88810">
        <property type="protein sequence ID" value="ERG88810"/>
        <property type="gene ID" value="J07HX5_00956"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954580_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="40"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14151" checksum="E58479A4A1A296D5" modified="2013-11-13" version="1">MQRTRYRERGQCINWGANQLFRAVFKHGESFARLFIAAAVIILALAGTYCQANLVIDNPDALQSEREFISNPLDAVYFSTLRFTTLGLGEFQPSAASQLGRGLVLLQAVLGAILIAMFVFVLGRRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXE3</accession>
    <name>U1MXE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00961</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88815">
        <property type="protein sequence ID" value="ERG88815"/>
        <property type="gene ID" value="J07HX5_00961"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="2"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="336" mass="35474" checksum="80D2A75FB40032CE" modified="2013-11-13" version="1">MIEVEDVAVSLGGVAVLDGVDLSVRSGEFVALVGPNGAGKTTLIRAINGVRPPDRGTIRLDGESTSELSSRAVSRRVATVPQDTHVGFSFRAEQIVEMGRTPHRSRLDWGGHDDPVEQALERTETAALRDRTVDELSGGERQRVLLARALAQETPALVLDEPTASLDINHQLRVLSLVTALTADGKTAVAAIHDLNLAARFCDRLAVLSDGEIQATGPPRAVLNTPAVETAFDTATAVTRDPVTGDPVVTAMDRGAAETADCRVHVAGGGQPAAATVRSLWTADIEPSVGPVAENSITARLAAALEIDVVTTPPFAALSRLRLPRPFNWPKPQTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXG1</accession>
    <name>U1MXG1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00981</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88835">
        <property type="protein sequence ID" value="ERG88835"/>
        <property type="gene ID" value="J07HX5_00981"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1574915_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="172" mass="19297" checksum="BF14213972DC6688" modified="2013-11-13" version="1" fragment="single">DVPEPSNPPDGCRFHTRCPEVIPPEGIDLPQETWRNVLHFRKQVLGDSVDLTSIVEIGAIENDLQVDETTPADVDEEQLASWVRSEYNLPGRLSDPQAEETLSTALTELITNGHQTAGETLTEQFETVCERQEPELRSIAPDHRVACHLTDDDLPGETDPENEYRRQLSSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXQ9</accession>
    <name>U1MXQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00939</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88793">
        <property type="protein sequence ID" value="ERG88793"/>
        <property type="gene ID" value="J07HX5_00939"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="357" mass="39348" checksum="7640782385E375D0" modified="2013-11-13" version="1">MKWYVAKRVAWSAVASLIILTIAFVLLDAVPNQSLQTVEFQAQQQGQSGEEAVEAARERLGIDGPLHERYIDFLINFAQFDWGWSNEYQQPVTETIIESLPYSMMYGVPSIIVSTVLGMAIGLYSAINQYTKTDYAATLFAFFGVSIPNWWFGIILLVLFGVGLGWLPIEFNERLAQNANGSLTLRETVDSANHPAFIGDSDVTGEQQVGVFTVRNLKQLVLPTFVSMTAGIAAMMRYARAEALEYVDAEFVKTAKSKGVSNWRIVARHILRPAAVPLSTILVGRFLGLFLTGSYLIEVVFGIPGLGVASFTAIENTDQDLVLATVLIPTFIVLVGNLMQDIAYVVLDPRISYGDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXY9</accession>
    <name>U1MXY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Spermidine/putrescine-binding periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01009</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88863">
        <property type="protein sequence ID" value="ERG88863"/>
        <property type="gene ID" value="J07HX5_01009"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_784377_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
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        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="359" mass="39480" checksum="F9233B51DB82A93F" modified="2013-11-13" version="1">MSQNSSRRSFLAGAGTAATVGLAGCTGIFSSNGTLSLLDFGYVYPDGIFDTIEDKIGTSVELKTSGSSANSLSLLRSGRADSDIVALGNYAVSPAIEEELIQPLNIDDISRYDGVFDFVQQDYFTADGQIYAAPRSFGQTPLAVNTDEVSAEEVTSLSVLFDQDYEGLVGHRDDARLQFLYERAANGKTPLNPSSADQVDFADTRDNLERHVELAGDLWGNGGSSEQLLRSGQVAVEPVWNYVIYSMNQSQDDFSVERVYPEEGTKAWYLQFCVREGADNVDAAHEFINAWYDGIGYQSLVEPSHIAVPHESVFERDGVDRAEYGLNQPERFIYEDPKPQSLVEDYTETWNEAKQAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY24</accession>
    <name>U1MY24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01054</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88908">
        <property type="protein sequence ID" value="ERG88908"/>
        <property type="gene ID" value="J07HX5_01054"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082928_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="227" mass="25014" checksum="5D7D610638CF4627" modified="2013-11-13" version="1">MSADDHSDADDGGPDTDDLNDEVQDRLEEEADSVIEQFDQGLIDLLSWLLETETRARIYVHLRQHPESTSEEIAEGTGLYPSTVREELAELHEEAWVTRHKRENGGAGNNPYEYGALPPSELVATTVDEIQSQLNTAFNLDQYLSDEDGDGDKDNIKTDSEPVTISVTDEQENENEDTGTGEPTTGTGDSEATDVDTETETDVDTDTNAETADSNEIDDHDDHDDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY41</accession>
    <name>U1MY41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01237</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89085">
        <property type="protein sequence ID" value="ERG89085"/>
        <property type="gene ID" value="J07HX5_01237"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="10"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="362" mass="39127" checksum="242BB09530B547D9" modified="2013-11-13" version="1">MDRSVSTPAIRVEGLEKTFKSGESEVTAVDGVSFEIETGQVVGLLGPNGAGKTTVIKSMLGLIIPDAGTVEIAGIDVHAQPNLAHNHVGAILEGARNIYWRLTVRENLQYFAGLGGDDPAALRDRHNMLLDQFGLADRENTTVNELSRGMKQKTALASTLARGVDVVFMDEPTLGLDVETSIELRAELRELADQEDVVIILCSHDMDVIEEVCDSVIVLSDGRTIKHDTIDALLGLFKTQQYEIIVDERLSGDPRSQLDRLSGVECDDRGEQLVISIRAADSAKVYAVMTALARSEPEIKTMQTVEPNLEEAFLRLTETDIGATQDGESGADPDQSGKASETSVSTQSASVDKITVSSDDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY57</accession>
    <name>U1MY57_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01257</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89105">
        <property type="protein sequence ID" value="ERG89105"/>
        <property type="gene ID" value="J07HX5_01257"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="48"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="171"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="33254" checksum="93EAF00FBA02AF40" modified="2013-11-13" version="1">MPGKYDDVLVSAEWADNHLEQFQADDPEYRLLEVNNPTVTEDSVHTPFEEGHIPGATFFHWEEDLSKQSTRDILDKDGFEQLNSEAGITPDSTVVIYGGGRVPNWFALFAYWEYKYFGHDDVRVIDGGKPYWVDNDFTLETETQSFTEQTYTASGPFDEIRAYKQDVDEAIDSGVPLVDVRSPAEFTGDIIAPEGLNETAQRGGHIPGAENVPTASVLNEDGTFKSPEELRNLYRESGITEDDSVVTYCRVGERSSIAWFALHELLGFDDVENYDGSWTEWGNLIRAPIETGQADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY82</accession>
    <name>U1MY82_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ribosome biogenesis protein Nop10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nop10</name>
        <name evidence="9" type="ORF">J07HX5_01283</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NOP10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89130">
        <property type="protein sequence ID" value="ERG89130"/>
        <property type="gene ID" value="J07HX5_01283"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196480_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00803">
        <property type="entry name" value="Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023532">
        <property type="entry name" value="Nop10_arc-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="SSF144210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6620" checksum="BA997EA6CCC96449" modified="2013-11-13" version="1">MKSDIRVCAAWASTHKQPVYTLGECCPECGATAVNTAPAPFSPADPHGEYRRALKRRHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYG3</accession>
    <name>U1MYG3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl1</name>
        <name evidence="8" type="ORF">J07HX5_01364</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Binds directly to 23S rRNA. Probably involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89210">
        <property type="protein sequence ID" value="ERG89210"/>
        <property type="gene ID" value="J07HX5_01364"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_A">
        <property type="entry name" value="Ribosomal_L1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023669">
        <property type="entry name" value="Ribosomal_L1_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="212" mass="23114" checksum="E30A3BD8F787D647" modified="2013-11-13" version="1">MADQELEQAVTRALEAAPSRNFSETIDLAINLRDLDLNDPSNRVDESIVLPEGTGQETSIVVFAGGETAVRAEEVADQVLDADELADLGDDDNEAKDLAGETDFFLAEEALMQDIGRYLGTVLGPRGKMPNPIGPDDDVVELIERLKNSVQVRSGERRTFHTRVGAETMSAEEIAENIDVITRRLEAELEKGPLNIDSMYVKTTMGPAVEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYG4</accession>
    <name>U1MYG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01215</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89063">
        <property type="protein sequence ID" value="ERG89063"/>
        <property type="gene ID" value="J07HX5_01215"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196451_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="8185" checksum="2269F0B2C1D7FE68" modified="2013-11-13" version="1">MTPTTDPDSNSGSDSDSTTVVPPTRRSCERCGRKELWHEDRATWTAADNRSGLAYCLHEWDITGTYNPLVEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYI6</accession>
    <name>U1MYI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent F420 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01390</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89235">
        <property type="protein sequence ID" value="ERG89235"/>
        <property type="gene ID" value="J07HX5_01390"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076368_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070967">
        <property type="term" value="F:coenzyme F420 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010185">
        <property type="entry name" value="NpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01915">
        <property type="entry name" value="npdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="22041" checksum="F90502D191F339AA" modified="2013-11-13" version="1">MQIALLGGTGDLGEGLALRLAPTDAAVTVGSRDPDRAADRATAYEQTLAEHGTPASITGAANPAAAADADLVVLAVPAYHLADTIETVANQLGDAILVSPAVGMQGTDTGLSYNPPGIGSVTELAAASAPDETPVIGAFHNLAAGRLATLDAELGWDVPVVGNDPNAKQAVLELLASVEGLHGLDAGGLANAAEIEALTPLLINLAANNERLHNLGVSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYL1</accession>
    <name>U1MYL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane-associated Zn-dependent proteases 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01417</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89260">
        <property type="protein sequence ID" value="ERG89260"/>
        <property type="gene ID" value="J07HX5_01417"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042134_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="565"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="6">
        <location>
            <begin position="123"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="6">
        <location>
            <begin position="515"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="591" mass="60899" checksum="2EE13F5E933AD229" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB9</accession>
    <name>U1MZB9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01536</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89378">
        <property type="protein sequence ID" value="ERG89378"/>
        <property type="gene ID" value="J07HX5_01536"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033707_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="76"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="349" mass="37516" checksum="4193BF52481898D4" modified="2013-11-13" version="1">MDLRLAFTRSEHTLRVLTESDGTVTGVSINDNYRSPAYVDTGSFASQETTLDADDCLMDACLTVPTGAARNSVPGVVLVHGNDPAGQADKNLETVGTQMFRDLAEGLSSAGVAVFRYDRRTNACPGTITPAGYTLDRVAVDDAVAAADQLRAAGPVDPDQAFVVGHSLGGLVMPRIVDRAGLAGGVALASPGREFFEIVVDQLEHQATVGEYTLEQAVTQFEIWRDQIDRVRAGDYQPTDTVIGYPGAFWDSVVAYDNIATARSIDAPLLFLQGAHDYQVTQADLDSLATALTDRPETQFRSYDRLNHLFMPVDLPSLADEYAVRNSVEASVIEDIAAWITSGGELPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZE7</accession>
    <name>U1MZE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01571</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89413">
        <property type="protein sequence ID" value="ERG89413"/>
        <property type="gene ID" value="J07HX5_01571"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2284943_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="101" mass="10995" checksum="FD85F0172768C0DA" modified="2013-11-13" version="1">MVAGGVLVYEPTPAGKELIGYESVTDWSQLGDAVATRGHDRGDALHLPVLDEQRHERTCRSASLGTQVWSAVVTGHPENTTILCRPAPATREDYRHTKTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZN9</accession>
    <name>U1MZN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01847</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89675">
        <property type="protein sequence ID" value="ERG89675"/>
        <property type="gene ID" value="J07HX5_01847"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_3_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="305"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="430" mass="48295" checksum="244ACCEF9DF1236B" modified="2013-11-13" version="1">MAWDITRTVQVCLDVPDDRKSDLHATNSKFQYCANRTAEWAWRYPDEDCVTSKSEAEAGIYDELRHTTNGLHANLVQKAIKRATDDIGNCVDRLADGENTSQPQYDTFSIVYDKRAATYYRDRVSLATVNGRVECDYDLPDNIEDTPHGEYLLNDDYSFSTSTVHYDSEADEFYLHAAMEKEIEASTPEKAEDSKVLGVDCNVDDHIAVTSTGLFVGNADYLNHQRREFEKRRASLQQTGTRSAHLTYHQIGDRFGRWSEDNLHQWANEIVAEAQRHTCTHVAFEDLEQIRERISDGKKFQQCAFNELQELVSYKTEMAGIVVETVDPSYSSQQCSNCGCTLEQNRDGQQFACLDCSYSVNAEYNAAKNVARKLALKLQRGQKSPAGGAFCQYDLNSGTLIVDATDVASDGYVSVERESTDKPTASAVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZY6</accession>
    <name>U1MZY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01942</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89770">
        <property type="protein sequence ID" value="ERG89770"/>
        <property type="gene ID" value="J07HX5_01942"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174522_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007355">
        <property type="entry name" value="DUF424"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04242">
        <property type="entry name" value="DUF424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10857" checksum="0A051D9051F53EE3" modified="2013-11-13" version="1">MPALLLTERETPEGRLVSVCDADVLGEQFERGDVSLTVDPAFYDGDTADEDRVVESLVRCTTANLVGTRAVGLAIKHDLVDEQNVLEFDGTRHAQLAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0B1</accession>
    <name>U1N0B1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02042</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89870">
        <property type="protein sequence ID" value="ERG89870"/>
        <property type="gene ID" value="J07HX5_02042"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1998669_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="13135" checksum="819781E8F633C335" modified="2013-11-13" version="1">MSATPLEQRRRRIDDRLEAVLTTVDPPALRDRLQRIVLAGGKRVRPLLTVCVADALDGDTETAVRYAAGIKLVHAASLVVDDIVDTAATRRGAPAAWVSFGPDGAVVASDGLIGEAFTLFAPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0C5</accession>
    <name>U1N0C5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP-dependent dephospho-CoA kinase</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dephospho-coenzyme A kinase</fullName>
            <shortName evidence="3">DPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01945</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3'-dephospho-CoA + GTP = CoA + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61156"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP-dependent DPCK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89773">
        <property type="protein sequence ID" value="ERG89773"/>
        <property type="gene ID" value="J07HX5_01945"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120795_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00590">
        <property type="entry name" value="Dephospho_CoA_kinase_GTP_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007164">
        <property type="entry name" value="GTP-dep_dephospho-CoA_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40732">
        <property type="entry name" value="PTHR40732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04019">
        <property type="entry name" value="DUF359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="195" mass="19741" checksum="0DC249B4F616CF01" modified="2013-11-13" version="1">MVLELSADLRETLKQPLGPVFTDVTTAIQQGTDTTATSRSSGPESGSGGRVNVIAVGDVVTSDLLAAGRLPRAGIVDGRTERSAVPEPVAERLASADFERERLAENPSGALTTGLAAAVAEAVDKTPTLVSVDGEEDLAALPAVLAAPPDTTVVYGQPGDGVVAVTADAAASDRVRAMLAEMDGDTEAFLAALST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0E5</accession>
    <name>U1N0E5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01965</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89793">
        <property type="protein sequence ID" value="ERG89793"/>
        <property type="gene ID" value="J07HX5_01965"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157001_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="11063" checksum="643AB41192D159DB" modified="2013-11-13" version="1">MSLLLAVARGAAITNVILLGSLLYVWGDNYRTHRATHTLGLLVFASVFVVQNLLWLSLYGFETTFIDWFETNGIGIQASLTGLCGLQSLALGFLAWITWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0H6</accession>
    <name>U1N0H6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02123</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89950">
        <property type="protein sequence ID" value="ERG89950"/>
        <property type="gene ID" value="J07HX5_02123"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="165"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="38556" checksum="D05EAD61624500D8" modified="2013-11-13" version="1">MTDVLELTTEMVAIPSHDSETAAGDRIETWLREHTDAIVERDQAGNVFARRGEAGADRLALVGHHDVVPPADTQLAADDDGYSVTRRDGRLYGRGTADMKGAVAAAMCAFRDTDREGVVFASFIGEEAGGVGARAAIENGFQPAYAVVGEGSTGYSAPGVTDVAIAHRGRRASTIHVDGTAAHASEPEAGTNAVYRAAAVVDEFQSLPAPATTVLGHEMAGSLAVTEIEGGSAWNVIPASCAITVDERTVPDHRAPLDRLTDRTGVNRAIDQDLPPMACAESAFAEHVQSAAETAQERSPAQVIKPHATDAGWLAQAGTTCVVCGPAERGEAHTADESVSTAALRRAYRIYRSVIEKFDRVSTAPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0H9</accession>
    <name>U1N0H9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02128</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89955">
        <property type="protein sequence ID" value="ERG89955"/>
        <property type="gene ID" value="J07HX5_02128"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2909104_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="7216" checksum="537C6939F0945039" modified="2013-11-13" version="1" fragment="single">IERLYEHVRSFLVATGHPEEKRDKALRLVRRLIGRADPTDREVVTLTGVFRRGTKRANKSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0N3</accession>
    <name>U1N0N3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation initiation factor 2 (IF-2, GTPase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_02035</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89863">
        <property type="protein sequence ID" value="ERG89863"/>
        <property type="gene ID" value="J07HX5_02035"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002656_3_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="486" mass="52562" checksum="3BF009F10A11887E" modified="2013-11-13" version="1" fragment="single">MPLDVVSEIAGELVDPDDFDLPGLLYIDTPGHHSFSTLRSRGGALADIAVLVVDVNDGFQPQTREAIDILRRTATPFVVAANKIDTVPGWSPVEGRPSKPAIDAQTDRVESDLTELLYELIGQLSDADFTADMYWRVQNFQENIGVVPVSAETAEGVPDLLTVLMGLSQRYMKSEMEIDASGPAAGTVLEVTETQGFGATIDTVVYDGTLSENDTIVVGARPDQIVTDVRALLQPKPLAEIRADEAFENVDSVVAARGVKIAAPDLDNAMAGAPIRAVRNRPVADVIAAVEAELAAVEVTTAEEGLTIKADTLGSLEALASTLADDEIPVTRAEVGNVAPRDVRMAQAATEPRHRAILAFNVEVLSDARSLATQEAVELFEHDVIYRLIEDYDEYVTEIEAAQQEQILENIARPARFELLPDHVFRQSDPAVVGVEVRGGVLRRNNRLVRFDGPEPERVGTLKTIQDEGDDVDEARTGDRVAVAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0T3</accession>
    <name>U1N0T3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl15e</name>
        <name evidence="7" type="ORF">J07HX5_02096</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89923">
        <property type="protein sequence ID" value="ERG89923"/>
        <property type="gene ID" value="J07HX5_02096"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080796_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00256">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_L15e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020926">
        <property type="entry name" value="Ribosomal_L15e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_L15e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="PTHR11847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="22528" checksum="82D557606144C3CA" modified="2013-11-13" version="1">MTRSFYSHIRDAWKNPDDGKLAELQWQRTQEWRDQGALERIERPTRLDRARSLGYKAKQGVVVVRAAVRKGGARKQRFTAGRRSARQGVTRITRRKNIQRVAEERATRKYPNLRVLNSYWVGEDGSQKWHEIIMIDPNHPAIESDDDLGWICDDVHDSRALTGQTSAGKQNRGLGERGKGTEHTRPSLSSDRNRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0W8</accession>
    <name>U1N0W8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cetZ</name>
        <name evidence="7" type="ORF">J07HX5_02136</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89963">
        <property type="protein sequence ID" value="ERG89963"/>
        <property type="gene ID" value="J07HX5_02136"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058152_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="415" mass="44621" checksum="0945EF3F72EA2A4A" modified="2013-11-13" version="1">MKIGLIGFGQAGGKIADTIIKDAKEWPSTCITSHFAINTAESDLEGLNNIPEERQILLDEKIDSDNGNISGGNGVGADNHLGAIVCKEQIGTIDSGLTTVNKQQTDAFVIVTALGGGTGSGGTPVLAQHINYTYPDMPVYVIGVTPTQSEGNVYVENTLESMKTVQQYVNGLFLVGNDSFRYSDEPISDLYERVNRTIAQRLLTLLAAGEVSSDGPAAHPESVLDTAEIVNSVSKDGFTTLCHAQETQSNTEKSVLGTLFSRSTSNDNENDHVVDYLDTADSDNTLLSLTKEAVNNNNSFEADISTADSALMLVTGDSDRFSQDELEASVSWLENKTNNAQVRTGDRPADIDKVSVLVLISGLNKSSKLSQFMQSINPDLDLSDKKTSQNVRKLLTTEQPETTVDEDIDKIAGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P337</accession>
    <name>U1P337_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00028</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87887">
        <property type="protein sequence ID" value="ERG87887"/>
        <property type="gene ID" value="J07HX5_00028"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_917047_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019207">
        <property type="entry name" value="DUF2092"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09865">
        <property type="entry name" value="DUF2092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="303" mass="33457" checksum="CB93B40127CE03B1" modified="2013-11-13" version="1">MTAVRSRHLVIGLVLSVVVALTGCMTPTADESELPAVEEVIETHDSVTSYTLEGTYLSTVDTRSLVQLETEQIVQPGTGEEYERITNERGNQTVWVSNGTVEWTYTAAANTVTRQTVDNNSSLDPSLNVDHEFVLELITQFNNDTTTTGSTQVLPLFVIGDPGDGQQDVATISPGDSNVSFNITYEGTQTVADREAYVIQMTGTDTRRNVTRELDQQLYIDTEWFIPLGYDAEIQTAEQTSQVEYQIENISFNQPVEDELFEFTPPTNATVVDPSTDIESFETKADLTETVANPPIXXXXXXX</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3J5</accession>
    <name>U1P3J5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00214</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88072">
        <property type="protein sequence ID" value="ERG88072"/>
        <property type="gene ID" value="J07HX5_00214"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965466_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="14656" checksum="516DF94E69A06EA4" modified="2013-11-13" version="1">MLRALSYTEQDQLDVQVTNVALLETLSRETIREEIGDVAAKYQQMQIRHAHVRFHEHKEQLRGTPLMQCQIRLRTNRGQIAGSGEGYGAKQAFRVAIDKLERRVLEIKGIQADKEYRGQLLRKLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3P6</accession>
    <name>U1P3P6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosylhomocysteine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00270</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88127">
        <property type="protein sequence ID" value="ERG88127"/>
        <property type="gene ID" value="J07HX5_00270"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="5">
        <location>
            <begin position="186"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="422" mass="46192" checksum="4EC5EA043683E9B8" modified="2013-11-13" version="1">MAPSRVTSPETDSDLEDPLTWTRDHTPLLQSFGEEFSREQPFDGLTVAVASHLEPKTGVFIETLRAAGAEVLFAPSEPQSTHGDVVGFLDAQQGYKAFAHEGMTDEEFNAAQHALLERAPDVILDDGCELIAKAHDAHPEVARDVLAGAEQTTAGITRLEAMDREDVLEFPVYGVNDTPMKHYFDNVHGTGESALANIMISTNAMVAGTTAVVAGYGYVGRGVAEKLRSLGADTIVTEVDPRRALQARMSGHRITDMTTAAAEGELFITATGSRAVIREEHFDRMQTGTKLANAGHFDVEIVVEDLERMAERTTDPTPGVTRYHLPDGRHLDLLADGRLVNLTGPYSQGHAAEVIDMTFAMMFMAAYDLVGRAERPPGLYTVPDRVDRQVAERKLETLGDEIDVVSERQAEYQADWRHGDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Y7</accession>
    <name>U1P3Y7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00370</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88227">
        <property type="protein sequence ID" value="ERG88227"/>
        <property type="gene ID" value="J07HX5_00370"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="81"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="417" mass="46248" checksum="0DF63C51F817F870" modified="2013-11-13" version="1" fragment="single">MTEQRRQERRTERFVEESEDVVSIVDPDGTISWVSGSAERVLGHDRNALVGETLFDYLHPDEREAAMASFFESVDGGADGTLTDCRMTDGDGAWLNVEGQVRNMLDDEAIDGMLVYLRDVTEQKERTRQLEAIFNGTYQFTGLLEPDGAVIEINETALDFGGFDQATVAGKKFYDAPWWTHDDQVRADAGSAVERAATGEFVRYEAEVQGADGLATIDFSVKPVPGDDGTTSMLIVEGREITALKQQRQHLTVLQRLIRHNMRNDLTKVRGWTWALYNETDPAEQTRQFERIEGVLEKWASMSQKLAEIRQVLNAQQASRSEVSPERLLAGALEQAETPPGAAIQTQASSTESLRVPQVIEEAVRELIENATETTDEDGTVIVELTEPDPGWLEITVSDDGPGLPATERAVLQTGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4C0</accession>
    <name>U1P4C0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00491</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88347">
        <property type="protein sequence ID" value="ERG88347"/>
        <property type="gene ID" value="J07HX5_00491"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170810_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021377">
        <property type="entry name" value="DUF3006"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11213">
        <property type="entry name" value="DUF3006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10872" checksum="9E38DECD7617DEE1" modified="2013-11-13" version="1">MIPDDSYIAVVDEIENELARLELTHDGSKTNRYGLVVDTAQLPAAARHQNAVLSVCVTDETLTKAEYRPTKTQRRRDSVQTRFDRLADRPPDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4H3</accession>
    <name>U1P4H3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="5">SDH</shortName>
            <ecNumber evidence="2 5">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">aroE</name>
        <name evidence="9" type="ORF">J07HX5_00537</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="2 5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88392">
        <property type="protein sequence ID" value="ERG88392"/>
        <property type="gene ID" value="J07HX5_00537"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044063_4_1_2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="6">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="8">
        <location>
            <begin position="229"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="5">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="144"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="27460" checksum="E003A4D70C71D221" modified="2013-11-13" version="1">MDVYGLIGSPVEHSLSPSLHEAAYDALGLEARYVTLEPEAGAAAIEAAKRLGVRGLNVTIPFKQDVLAAVEPAPLAAQIGAVNTVDFASDPPMGYNTDATGLVQALTNHGGELAGTAVVVGAGGAGRAAAMALAEEGMAVRVANRTVSRAERLAAAVDGTAAGLDAVPELLVDAELLVNATSVGMEEDRSPVPADALHAGLTVLDAVYTPAETRLLQDAAAAGATTVEGSWMLLYQAVAAVERWTDRDAPVAAMNRALREELDSLSPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P529</accession>
    <name>U1P529_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc metalloprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">J07HX5_00793</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88647">
        <property type="protein sequence ID" value="ERG88647"/>
        <property type="gene ID" value="J07HX5_00793"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037123_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016483">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006404">
        <property type="entry name" value="UCP006404_Pept_M50_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="317"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006404-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG88647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="41850" checksum="55C36F2B9F2D3346" modified="2013-11-13" version="1">MRGLHIGTIAGIPVRLNWTFLVVLPVFAFLIGTDITMLTDLLEETLGRDIAASTLEGSYRPWLLGLAAAVGLFGGVLLHELGHSLVALRFGCAIESITLWLLGGLASFDEMPENWRQEFWIAVAGPVVSVGVGLAFFAAFLAVPSGVNELLFVFGYLAVVNVALAAFNMLPAFPMDGGRVLRALLARNRSRVRATRLAAGTGKVFAVGFAIVGVFANLFLVVLAVFVYIAAAGEAKQTVFKAAFDNVTVGQLMTDREALETVRPDATVAALIQRMFAESHTGYPVVGEPGYVGIVTLDAATSVPEVEREAYLVEDVMQQDVTAVRPTTGAMTALEAIQQEDTGRLLVVDDDRLVGLISRADIMRGFNIIQSGGQPRSPDESRRGGPAGELTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P558</accession>
    <name>U1P558_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00828</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88682">
        <property type="protein sequence ID" value="ERG88682"/>
        <property type="gene ID" value="J07HX5_00828"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1727174_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
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</entry>
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</entry>
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</entry>
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        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
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    </dbReference>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Y5</accession>
    <name>U1P6Y5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01490</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89332">
        <property type="protein sequence ID" value="ERG89332"/>
        <property type="gene ID" value="J07HX5_01490"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930079_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="7104" checksum="3EDDD61D881286CE" modified="2013-11-13" version="1">MSTLPAVHEYERFTDWVLDASLDTDVNSHEFWKLRQQETEAAFLSWARRVANETIFQSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P704</accession>
    <name>U1P704_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00027</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87886">
        <property type="protein sequence ID" value="ERG87886"/>
        <property type="gene ID" value="J07HX5_00027"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1912268_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="15003" checksum="734A7BF526A5339D" modified="2013-11-13" version="1">MRQRKRPTTRNVAQRLGVEPDQLTHFVDYHPDPAPSDLCELPDTDPRPLDRASRQLIAEWLDDRAGWDFVTATEITDYLAEHGPTDRAELPEALGVENRRVYHAAKQGLKEAGEIEVIETDWGLPTGYRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P797</accession>
    <name>U1P797_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA-binding protein, contains TRAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00147</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88006">
        <property type="protein sequence ID" value="ERG88006"/>
        <property type="gene ID" value="J07HX5_00147"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121271_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="15475" checksum="9C92D6F5CAD10F9E" modified="2013-11-13" version="1">MQISDELVCLYTAEVGATDDTHTIDVPQREIEQGTIAEGEQYRIAILTADTPDTTTHDQTDPTRSQHRATEQQQPAPPVTEGEIREVEIESLGDQGDGIAKVDRGFVLIVPDTEIGERVTVEIGDVGSNVAFAAVVDRHHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7A1</accession>
    <name>U1P7A1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00152</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88011">
        <property type="protein sequence ID" value="ERG88011"/>
        <property type="gene ID" value="J07HX5_00152"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1582845_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046157">
        <property type="entry name" value="DUF6159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19656">
        <property type="entry name" value="DUF6159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="168" mass="17553" checksum="887A1095BE7980CA" modified="2013-11-13" version="1">MISATVGLLLDALTESDSLPAQIISGVLGVSWALLTFFIIPVIVFEKPSTTGMFRQSGQTFKKTYGESVVSLFGATVVGLLAALPFVAVGGAIILVTGVTAAALPFIVIGVAVGQVVTFSIRGIVKTGLYFYAQEGERPTEFDEIFDQLNLSGQRDGAQTTGSQFGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7N2</accession>
    <name>U1P7N2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01733</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89567">
        <property type="protein sequence ID" value="ERG89567"/>
        <property type="gene ID" value="J07HX5_01733"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_932566_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="32968" checksum="8A0C274E4C9F4CC6" modified="2013-11-13" version="1">MLKSIGAMGIFASTFATTAATRARATPTTQTDDPLNDFDPVWRSVKETTWYEEEFYNPMWEADYPEGGISIRRVLVLNDYAGQENREGHLYEFGLFSIGVSAYAKDVDGRHISYEGIFPDGVWHSTHEITCESTDPDLFDVQERVNPTHPRVIAGISNDKITETPTTDGWIGDYTKKADLDNVSVNIRGPDVYLGTTGLGIGLMGSALSGGMAAVFAGTSYGLPAGSLIAGVSDNDTEFFEQRPDKLIYTFRDEGIGGVNDIGAFSHSVRFYISVKNHEGPRLKIGDKNRTQWERRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Q3</accession>
    <name>U1P7Q3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">J07HX5_01753</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89587">
        <property type="protein sequence ID" value="ERG89587"/>
        <property type="gene ID" value="J07HX5_01753"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_3_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO" evidence="12">
        <location>
            <begin position="49"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG89587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="33090" checksum="0DF785EE76B91A95" modified="2013-11-13" version="1">MEDDYGLLETDQAQPGDEWTAIDYTDTEADQIARERDREFSQFRDRITDADQFKLKESVFDEATYGALYKLVQDGQIAAFGGPVSTGKEANVYTAIGGAAAREALNESAEPTVAVKLYRINASDFREMGVYLEGDPRFDEIANDKKAIVVGWVRKEFANLQRALAAGVRVPRPLAVERNALVMEYLGTNTGRAKRLAEVHIENPATAYEVVREYMRRLYDAGMVHGDLSEYNIVVDESELYLIDVGQAVTVHHPNSDQFFERDCENVASFFSRQGADVTPAELSAYVREHADPTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Q6</accession>
    <name>U1P7Q6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00319</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88176">
        <property type="protein sequence ID" value="ERG88176"/>
        <property type="gene ID" value="J07HX5_00319"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1393538_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="195" mass="20524" checksum="FAAFD68631930D71" modified="2013-11-13" version="1">MINPHGPYVCPVDQSRARQEAASRACESPVLVPVAAVMSVSVLIFAGPAIVVVSVLSVVAVGHALQFACSIIVNALLHSSGPPPREVASTVTSRSPPAATASVTHITSLACACAGKLRVNAELVGGRLLAGNQRVDRANRFDALEIVESSPDHLGQLLVVCVPDGTELPPKHRDSPRRQHREHRRPGALVDRANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P817</accession>
    <name>U1P817_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01879</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89707">
        <property type="protein sequence ID" value="ERG89707"/>
        <property type="gene ID" value="J07HX5_01879"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068376_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="57"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="246" mass="26155" checksum="194DF889AEDDAC2F" modified="2013-11-13" version="1">MTPAQANNPATRLYPSTTSMMAGGYFRVSVPTKQAATPGARRSSNAHICRTHSKNMYDVIVIGGGVAGLQAAVFTAKAELETLVLDDGTPLVASTDKIQNLITEERIAGEEIIQTGRERVEAFGGELAEATVTRLARQTDSPALVVTTEDDTTHTATAVIVATAGTLDFLAPLADELAYADGREGEFTMEHHVVTDDANRATDDVYVAGLANTWEYQTAVAIGDGAKAAVNLVSDRRGEAYVDHDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8D7</accession>
    <name>U1P8D7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="2">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="2">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">msrA</name>
        <name evidence="4" type="ORF">J07HX5_01989</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89817">
        <property type="protein sequence ID" value="ERG89817"/>
        <property type="gene ID" value="J07HX5_01989"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="3">
        <location>
            <begin position="7"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="179" mass="20196" checksum="D3650A851681065B" modified="2013-11-13" version="1">MATTEHATVGGGCFWCVEAAFKQIEGVASVTAGYAGGQTDDPTYRAVCSGRTGHAEVIQIAYDPDRISYEELLEIFFTVHDPTQLNRQGPDVGSQYRSIVLHHDDEQRAIAESYLGALAEEGGYDDEIVTELERLETFYRAEEKHQDYFEKHPNDAYCTMHAQPKVEKVRERFREKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8G8</accession>
    <name>U1P8G8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methionine-R-sulfoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02014</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89842">
        <property type="protein sequence ID" value="ERG89842"/>
        <property type="gene ID" value="J07HX5_02014"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_8_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="2">
        <location>
            <begin position="14"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="15062" checksum="847AAEDA292CC57E" modified="2013-11-13" version="1">MTDQAGETPQPQTDEQWKQELTDEQYRVLRTGGTEPAGTSELLGIDDDGVFRCVGCETELFHSNQKYTSGTGWPSFWDPADEDAVATQRDTGLLGFRTEVLCAECGGHLGHVFDDGPEPTGKRYCINGAALEFAEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8W5</accession>
    <name>U1P8W5_9EURY</name>
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        </submittedName>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="8550" checksum="D87CBC6AC1D81B55" modified="2013-11-13" version="1">MSQTETITERITRWAEDGQLYVIAGVLSAVLSLLVLPVAGGVGVYCGYRLYSTTDRSSAGIAILLASVTGLVLPFVFIALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9G7</accession>
    <name>U1P9G7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type branched-chain amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00922</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG88776.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="281" mass="30803" checksum="3B39BF0E3D3B209B" modified="2013-11-13" version="1">MAHTQQTTSGSGLRSGPAVPPEESALGCRAVTRTFGAITAVDTVSIGIDDGEWVSIVGPNGAGKTTLLNVLNGFYDPDQTADPQSGRIFLNGTDVTDAPTYRRARQGLGRTFQGLELYEEEDVIENVMAIRAVHDRPGLVSSLTYLGPGRQLEAESMRRVEEIIDYLELWEYRHSTVESLPLGIQRRVDLARTLALEPDVLLLDEAMSGLTSDEKYDMFRFLADLHEQEGLTMVMIEHDLEVVTDVSGRMIVLHQGGVIARGDPDAVVADSEVRRIYTGVD</sequence>
</entry>
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    <name>U1P9Q0_9EURY</name>
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    </gene>
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        <lineage>
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    <reference evidence="1" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88841">
        <property type="protein sequence ID" value="ERG88841"/>
        <property type="gene ID" value="J07HX5_00987"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965467_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="14243" checksum="14C23E7A28BC6F35" modified="2013-11-13" version="1">MVERLDSEPHRELAENYVVSTTPALPKRTQRPVLRPPYVTKQTYQSRCPENDQLEPLLKLTIPHNEYYDIVDDVFDGDVADGYEPTVFLLNESLIPLLTSLVHQLGPEAVSIGSIDPASASPVSARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA95</accession>
    <name>U1PA95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01176</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89026.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_15" evidence="2">
        <location>
            <begin position="278"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <sequence length="654" mass="73522" checksum="90DEE9B9281DB42D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAJ1</accession>
    <name>U1PAJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89116">
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="15972" checksum="FCA60E18F374AF9A" modified="2013-11-13" version="1">MTATVGSVPILLVTTTFEVTDQTGATCGVFISVVAASWRTLAHGSDGVAWGWAQHLSTKAPRGHRWPRQDQSTSVNASTTTGSSETCDDDACPLLSNGSTARVNAPASVVVNTSGRPAIRTSVYSIRGCGDRSVSQSIRLYGLKPRVLYSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB17</accession>
    <name>U1PB17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01438</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89281">
        <property type="protein sequence ID" value="ERG89281"/>
        <property type="gene ID" value="J07HX5_01438"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_503100_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="541" mass="58751" checksum="148BBEA61FFEFED8" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCJ9</accession>
    <name>U1PCJ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase, FAD-containing subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01988</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89816">
        <property type="protein sequence ID" value="ERG89816"/>
        <property type="gene ID" value="J07HX5_01988"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="343" mass="35800" checksum="A8842A6D676E2927" modified="2013-11-13" version="1" fragment="single">MHVAVFGAGYAGLATVRRLQRSLPGAVRLTLVDETDYHLAQHLLHYVIRDPELESELTVDLTAALDRAVHRQTRVTGVDPDAGVATVADGQLSYDIGVVALGAGAAFGGVPGAAKHGTPLKQLSHARAIRDRFDDLAPTERAVVVGGGLSGIQVAGELAMLADNEDDGATVVLVERSATVAPGFSTEFQQTIRAALIDAGVEVRTDWGVTEVTPDRLQLEAGGSIGYDQLVWTGGITGGQAMGDRPQVRADLRLGERTLGLGDAVSVVDANGTAVPASAQTAVRQASVAATNATRLVEADRTGTQPPLERYRYDGLGWLVSVGEETVARVGSTVFRGPAARVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCX8</accession>
    <name>U1PCX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative peroxidase-related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02119</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89946">
        <property type="protein sequence ID" value="ERG89946"/>
        <property type="gene ID" value="J07HX5_02119"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010195">
        <property type="entry name" value="Uncharacterised_peroxidase-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01926">
        <property type="entry name" value="peroxid_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="188" mass="21012" checksum="B2EBE3E1F76CE5A5" modified="2013-11-13" version="1">MSESAMTRFSVPDLEELPEAVRDRIESERERAGFVPNVFPAFARRPRQFAAFFEYYDAIVEESPLAREEIELLIVAVSGANDCLYCVVAHGALLRLYAEDPELAEQVATNHRTAAISDAHRAMCDVGVALTDAPATVGDEELARLREHGFSTEEIWDIGSLTALFNLSNRMAHFVDLRPNAEFYSMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCZ7</accession>
    <name>U1PCZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_02139</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89966">
        <property type="protein sequence ID" value="ERG89966"/>
        <property type="gene ID" value="J07HX5_02139"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_16_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="182"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="309"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="365" mass="41863" checksum="FB2E63889CF786DE" modified="2013-11-13" version="1" fragment="single">MAIQVTRTYVGHITNQQRVRDDLDLLGDAASKLWNVARWTVDRVWDAIGEIPDEGSLKAYMKTRECWKNLNAFSSQKVIEELSDAFQSWFDVRHKDETANPPGYRKEYDTRPRSTVTFKANGFKHDPDHDQVRLSKGANLKDGRSDFVLCEYDTRNDVDLGTVDTVQNVRAVWNGDEWEIHFVVKETIETPEPPGDGVAGVDLGVSNIAAVAFPDKYVLYPGNTIKQDNHYFQQEEYDTEGENGPSKQAQRLRQKRKRRETHFYHTLTKTIIEKCVDRGIGTLVVGWPEDVRSDDLGKTANKWLHTRAFDRLYQYLNYKGKEHDVEVLKENEWNTSKTCCECGDIADSNRVERGLYVCDSCGLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFI7</accession>
    <name>U1MFI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00010</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87869">
        <property type="protein sequence ID" value="ERG87869"/>
        <property type="gene ID" value="J07HX5_00010"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075178_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="52" mass="5711" checksum="4EA8CE2539D7A50E" modified="2013-11-13" version="1">MTTSYDEIAVDIHPRIGGVSRFIPISSSQYRSDLAFAGSLFSRVEYSAIAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFL7</accession>
    <name>U1MFL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease HI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00065</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87924">
        <property type="protein sequence ID" value="ERG87924"/>
        <property type="gene ID" value="J07HX5_00065"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1375506_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="65"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="21265" checksum="4A6DA83E63C40FB9" modified="2013-11-13" version="1">MPVIQCDPRQARRRLEAADVTVADGNTQHELWRADHAGATAVAYDEKVVVQGAKTGRLEGVLRDGDGRVSVYVDGASRGNPGPAAIGWVLITDGGVLTEGGQRIGATTNNRAEYRALVHAVEVASESGFGTVDIHSDSELVVRQVTGEWAVNEPALRELRVRARELLEEFDDWSLSHVPRELNERADKLANEAFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFW5</accession>
    <name>U1MFW5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00205</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88064">
        <property type="protein sequence ID" value="ERG88064"/>
        <property type="gene ID" value="J07HX5_00205"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504830_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9124" checksum="46EE778F543F1BB1" modified="2013-11-13" version="1">MLKEFSRLDGAFVVSDSGKIVSAYRYLEPGAEGVDIPKGLGARHMAAGAITRDTNAVAIVLSESDGLVRAFKRGRKVLELDPEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG11</accession>
    <name>U1MG11_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">DNA repair and recombination protein RadB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">radB</name>
        <name evidence="6" type="ORF">J07HX5_00267</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic RecA-like protein family. RadB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88124">
        <property type="protein sequence ID" value="ERG88124"/>
        <property type="gene ID" value="J07HX5_00267"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041732_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00350">
        <property type="entry name" value="RadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011939">
        <property type="entry name" value="DNA_repair_and_recomb_RadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003336">
        <property type="entry name" value="RadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02237">
        <property type="entry name" value="recomb_radB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="5">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="230" mass="24591" checksum="54DB6D84EC3933BC" modified="2013-11-13" version="1">MTNPDPTPTGCGPLDKLLGGGFDRGAATQVYGPPAAGKTNVVLSAAVEVAARGGSALYIDTEGLPIERMEQLAAAHDTDTDTLASRLIISEAMTFEQQREAVRDAESFAESVELIVLDSATGFYRLERNADDNGETLRAVTRQITHLLALARKHDLAVAFTNQVYTDPESDTTRGLGGQTIDHWSAVILRLDRFRGGNRRATLEKHHTKAAGDRAGFKLTDDGLAGADTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGQ4</accession>
    <name>U1MGQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">K+ transport system, NAD-binding component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00534</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88389">
        <property type="protein sequence ID" value="ERG88389"/>
        <property type="gene ID" value="J07HX5_00534"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2054441_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK C-terminal" evidence="1">
        <location>
            <begin position="35"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="12898" checksum="AECC7E921C63910E" modified="2013-11-13" version="1" fragment="single">PENVSAFKGLDVTAIDASTATAFAIDNEIERPSMAHWMDELGEGHDVQECTVTAEDYVGRSIEQLNAQMPDGVIVAIVASDGNEYVPTATETIGKGDRVTFVGDKDGVKEAVRRFDPRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGT4</accession>
    <name>U1MGT4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00579</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88434">
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        <property type="gene ID" value="J07HX5_00579"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
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        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="16"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="508" mass="55788" checksum="CDEA8CF6149C940F" modified="2013-11-13" version="1">MSQHTEPYGQYIDGEWVAGQGTETFESVNPATGRPLATFERATEADVDQAVRAAESAAEEWRGYSYIDRAEVLWEVFRELRDRHTELGEIVTMESGKEISEGKADVTEAWHMVEWAAGNARHPHGDVVPSEIAAKDSYMRRKPRGVVGCVTPWNFPVAIPFWHMAVSLVEGNTVVWKPAEQTPWCGQIVAEMLADAGVPDGVFNLIQGFGDAGSAIVGDERVDTVLFTGSAEVGHQIADQVAGDPGREVALEMGGKNAVVITEAADLDVALHSAVMSSFKTTGQRCVSSERLIVHTDVYDEFKREFVELAEQVAVGDPLEEDTFMGPVIDERQVEKFHRYNKLARTEGATVLVDRADLPPAQIPEDHEDGRWVGPFVYEIEYDPTLRCLREEVFGPHVALIEYEGSVDRAIEIHNNVSYGLAGSIISDDYRQLNRYRDHGEVGLAYANLPCIGAEVQLPFGGVKKSGKGAPSARTVIEAVTERTAWTVNNSTDIQLAQGLSADITTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH94</accession>
    <name>U1MH94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative phosphate-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00820</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88674">
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        <property type="gene ID" value="J07HX5_00820"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002094">
        <property type="term" value="F:polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039074">
        <property type="entry name" value="GGGP/HepGP_synthase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038597">
        <property type="entry name" value="GGGP/HepGP_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008205">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
    </dbReference>
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        <property type="entry name" value="PTHR40029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01884">
        <property type="entry name" value="PcrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="424" mass="45002" checksum="E017EE61B3298AD4" modified="2013-11-13" version="1">MSLGTLAGRIERLASAVSIGARRILSLDTNPVPAAWTHITKVDPEARKHLPLLFVPYLSHTSAVSVGGSRAVTGENTAETFELINAASVPAVHEPSAAKHVTATARDQADFLVVPEVLNGDVEALVGTLGKGVGYVRDDLGPRTVEKVLGLAPGGILGDRLSDAAAAWLLEEAVFEAYIIMNPDSAAAREANVDAEDCLSPQVARERALAAEYHLDSEIVYLEYSGTYGGAEATELLGAIDDGCKWSRIWYGGGVDSREKAQQVLDAGADAVVVGDAFHEVATEEQALYEQATERFDDDPGAETMCRWVATTIEPNKTNAARYLSTVPSVPSPARRAVRYLATGLRLGLALRTIADELEGSAPDPQQLRAAVAEQQLPGESAFADVLDSGASERVREIGVAMLADRLETDLNSGLPTRHIGITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHE2</accession>
    <name>U1MHE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00880</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88734">
        <property type="protein sequence ID" value="ERG88734"/>
        <property type="gene ID" value="J07HX5_00880"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079333_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="13641" checksum="65B6B5A7E3E75E7D" modified="2013-11-13" version="1">MIEAVQYRFGAHTTADDPTVYREESEVERWKQKDPIPRFETFLRDQGILDDERVATIEQAVEDEVADVITTAEEMREPDPAEMFASVYESMPGRLDDQLRYLSRLREEHGDDTLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHF6</accession>
    <name>U1MHF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00895</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88749">
        <property type="protein sequence ID" value="ERG88749"/>
        <property type="gene ID" value="J07HX5_00895"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3379857_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3791" checksum="CA3DFF2FC5F195A8" modified="2013-11-13" version="1">MMPGNCQFALCSSRLYAPAERRLQDAFSWVGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHS1</accession>
    <name>U1MHS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01005</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88859">
        <property type="protein sequence ID" value="ERG88859"/>
        <property type="gene ID" value="J07HX5_01005"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_2_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15018" checksum="39A1E33773611A20" modified="2013-11-13" version="1">MIGEQARCRSLKTATSAVVGYSCIIDLSNRDDQAREQNWVRGKAFDGAAPLGPVVAPPATVPADARITLRVNDEQRQAATRSELVFSVPELIAEITQYCTLEPGDIIATGTPAGVGPLQPGDEVTVTIEGVGSLAHSVDSPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHV4</accession>
    <name>U1MHV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">4-amino-4-deoxy-L-arabinose transferase related glycosyltransferases of PMT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01050</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88904">
        <property type="protein sequence ID" value="ERG88904"/>
        <property type="gene ID" value="J07HX5_01050"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1226994_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="91"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="24726" checksum="05973287AB0AC4FA" modified="2013-11-13" version="1" fragment="single">MARQPAPAQSTTARDRLSARLSLNHVFLAVLIILWGWFYLRGLGDLPVRVWDETRYAMPAQLMTDGGSWLTPHIRVPTHSTDLGLQRRIVKPPLVYWLQALLMSVFGVSEFAARLPTALATLGCAVLVYHIGRHVYDRRAGLSGALLLIVFPGLLLGSHGGRAAVSDTTLMLFGSLFVWFTWRGRKRPRLLVPAGVLAGLAVMTKGVAAGVFVIVLLPVVLASLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI10</accession>
    <name>U1MI10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prephenate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01129</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88979">
        <property type="protein sequence ID" value="ERG88979"/>
        <property type="gene ID" value="J07HX5_01129"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_0_2_2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="185"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="28691" checksum="4D1968C610A642B3" modified="2013-11-13" version="1">MNVLTLGPAGTYSHRAAQAIADGGETVFTEAVAGIVEAVAGGSHDRGVVPVENSIDGSVTEALDAFADYDVAVTREIVTPIRHALLGQRERFDTVASHAQALAQCRSYLEEQYPGVDRQTVASTARGVEHAQNEPTVAAIAHPGNATGDLSLIAKDIQDRSSNATRFLVIGPTSAGTKAGSKTSFIVYPEVNYPGLLLELLEPFAEHDINLTRVESRPSGERLGDYVFHIDIAAGLYEERTSAALEVVESVADEGWVRRLGSYDTETVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI63</accession>
    <name>U1MI63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HDIG domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01205</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89054">
        <property type="protein sequence ID" value="ERG89054"/>
        <property type="gene ID" value="J07HX5_01205"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036524_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="50"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="176" mass="19488" checksum="5E36B7044497777C" modified="2013-11-13" version="1">MGVEVRESPVSEQAFTEMRQFVRDYLAASVETEQDGGRMRWYPWHSAAYRFNHIENVVELSAQIARAEGANVDATRTAALFHDIAKLEVEQDAHADEGAQVAEKYLTSHGEYPSSFTGQVTQAVRDHSYQGPVTDLPLETQCLVEADVLDKVGANGVALVILRMGMRPALTPTPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIV1</accession>
    <name>U1MIV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01507</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89349">
        <property type="protein sequence ID" value="ERG89349"/>
        <property type="gene ID" value="J07HX5_01507"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1922705_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="131" mass="14033" checksum="0C594893BB83D514" modified="2013-11-13" version="1">MRGDADETVIYDRRHRLEAAATREAGGGQAYRSTGGTLLAEDWLAEPGPIRCTFTVPAHGLAASFDADEATIGGQLVSNAEQSPCYFLKARVGGEKSPVTTSTSTVPERLTVVSDWYDTDIFDYDHAGSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ94</accession>
    <name>U1MJ94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01700</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89534">
        <property type="protein sequence ID" value="ERG89534"/>
        <property type="gene ID" value="J07HX5_01700"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1006864_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="31189" checksum="E75009020D74BAF6" modified="2013-11-13" version="1">MEVLAVTVPPARRCAMCEREAVNPERNGALCQRHLAAIEDDPETDKTTELKTEIPAPSSEKDVDPSRSSGLEEPRNTLEHRADYSPEGSWHSLDFSTTDPDTYPDALRECEQWVVQGESLSPFERDKAPYAPWGNDDPARWGLEDNRTEFDTAHEWAICDPRVDGLALIQLELDQYVFVDDDVRCPETGDVHPGFLSLLDRLDDLWGHFDIRKRDTLQSKQRGAVMSGAMMAYIASMTTVRWNSNRSISIHSMIRGXXXXXXXTYANAMLTHIAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJA1</accession>
    <name>U1MJA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01710</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89544">
        <property type="protein sequence ID" value="ERG89544"/>
        <property type="gene ID" value="J07HX5_01710"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098905_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="189" mass="20763" checksum="0FB09EBB727D6AD2" modified="2013-11-13" version="1">MQLAEAVWRETLGLPEPEREQDIFIGQFLVLFMSEQTDRQLDARSRRRFLTAAATIGATAVAGCSNVTNQLADAVVDDVVVQNTRESKVGGQINITTPTGTIGLEETFDLNDKDEGNIQLYEDVWTTEGSYEASLKLTRAGFDGMDSVTETVSVATPEEETLTVKFTADETKDPITLCVQDDPDLSYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJC4</accession>
    <name>U1MJC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase of the AAA+ class</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01740</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89574">
        <property type="protein sequence ID" value="ERG89574"/>
        <property type="gene ID" value="J07HX5_01740"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_646568_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="202"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="439" mass="48721" checksum="B20D48703FFDDFA7" modified="2013-11-13" version="1">MTDPEFAVVEFVLTTSLFNDTNDLGPDDLPPDHRRPFWTDGQIERPVTPTVDAAREATNVDRPWDAVSGLMFTDHDSFSGTLSLTDRSMAEQWYLDRATDEQIGANPVLAAQFADQRDVSLEQAREETRPARADRAYIDALLEEYFDEEEDEMLDLVDVTVPADIELQIEDIVLTGEQEGEINKIVKAIEHRDYLATIGLSEIGKLLFVGPPGTGKTSVARALACELDLPAVEVKLSMITSQYLGETAKNVEKTFEAAKRLAPCVLFMDEFDFVAKTRASDEHAAIKRAVNTLLKSIDEVSLIDDEVLLIGATNHPDQLDAAAWRRFDEIVNFPKPDIEMRADIFKIVTREMEIVDFDPEAAAELTEGLTGSDLRLVLREAVLGALTEDRTTLTQQDIVDAVKEVEERDTLKNLDMIEGDHDALVAGGLGDGADHAHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJE3</accession>
    <name>U1MJE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01760</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89594">
        <property type="protein sequence ID" value="ERG89594"/>
        <property type="gene ID" value="J07HX5_01760"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="12"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="349" mass="37017" checksum="92BB0FC3C0B90494" modified="2013-11-13" version="1">MDMQAVQFSAHGGRDVLAYDTLPDPDDPDRDAVIVEIKAGGLNHLDIWTRRGLPGVELELPHVPGSDGAGVVRAVGPDVDRFAEGDRVALSAGVHCGSCEFCRAGDPTRCVSYHVIGEHVRGVHAEYATVPADNLVAVPTGVDWVTAAAAPLVFQTAWRMLMTRGELSAGESVLVLGASGGVGHAAVQIADYAGAEVYATASTDEKLAYAAELGADHTINYEKQDFAAAVRDQTDKRGVDVVVDHVGAATWQDSLRSLAKGGRLLTCGATTGGSPETDINRIFWNQLEVIGSTMGTPGEVDDVLELVWNGPFEPRVRDVLPMSKIARAHELLETRTGFGKVVVRPDSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJJ2</accession>
    <name>U1MJJ2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F420_ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01825</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89654">
        <property type="protein sequence ID" value="ERG89654"/>
        <property type="gene ID" value="J07HX5_01825"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2745701_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002847">
        <property type="entry name" value="F420-0_gamma-glut_ligase-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01996">
        <property type="entry name" value="F420_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_ligase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7626" checksum="682EC245BDE49645" modified="2013-11-13" version="1" fragment="single">MELFAVEGLPEIHPEDDLGALIADRTDLQSDDVVCVASTVVSKAEGRGTDLTAFPANDRATAIADRLDRLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJK1</accession>
    <name>U1MJK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPFH domain, Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01835</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89664">
        <property type="protein sequence ID" value="ERG89664"/>
        <property type="gene ID" value="J07HX5_01835"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF117892"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="31758" checksum="2FFC30B8E62A6365" modified="2013-11-13" version="1" fragment="single">IYRFDMRTQTLDVPRQEAITRDNSPVTADAVVYIKVMDAEKAFLEVDEYKKAVSNLAQTTLRAVLGDMELDDTLNKRQEINAKIRQELDEPTDEWGIRVESVEVREVNPSKDVQQAMEKQTSAERRRRAMILEAQGERRSSIEEAQGDKQSNIIRAQGEKQSQILEAQGDAISTVLRAKSAESMGERAVIERGMETLEEVGKGESNTFVMPQELTSLVSRYGKHLQGSDTKANGHTLEGLEFDDETREMLGLDDIEQILGELDSEDDVVTSSRWKRRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK41</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02072</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8546" checksum="46D9816225C41DDD" modified="2013-11-13" version="1">MGVKHITARLGALRDRVPWWYFVIAGVVAGYQSVTVFLGVFDPPFWPFADQIYAVYCAGVTVTALPSAYSAQRGTGSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK53</accession>
    <name>U1MK53_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Putative endoIII-related endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02092</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48150"/>
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    </dbReference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="35" mass="3841" checksum="FF172771AEF5E160" modified="2013-11-13" version="1" fragment="single">CTARNPDCGECVLEDICPSSKRDSDRDLASGEPWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK70</accession>
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        </submittedName>
    </protein>
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    </gene>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG89944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="205" mass="23626" checksum="9D40F8E7642E1FA5" modified="2013-11-13" version="1">MSDSDSGTQSEDPLAAVPDWDDEYVDRVSDRLLHNYDLERNKTVQDRRFTLYGQLAIKRRKQFFHPALTYGDHETTEHLLVQRTDSVSVADMERLSKLGDQLADEWIVPDEEHFGTEFVFGVVAPRVPDEVQAFVSEFETRTLLKYGYHGHYSVRLFVVAPEKQSSVASPDVDVVRAFRLWDENSEQRSEKSNGVVSRLRAVFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV00</accession>
    <name>U1MV00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00026</name>
    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87885">
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        <property type="gene ID" value="J07HX5_00026"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2461651_0_0_2"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="10219" checksum="046A8F7F644957D4" modified="2013-11-13" version="1">MTVCNIRIGNLNPEHPPVDYERGQAMWLSPRDCAHLHDRALQAEYEHETVYGISDNDRKYYALERAKNELGYEPQDNAAEWDGTEKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVB6</accession>
    <name>U1MVB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_00034</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87893">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7336" checksum="78BCF378F470E3B7" modified="2013-11-13" version="1">MTEFLAPLIHYLPSLKPDNGVPVEYNEGTGAATRSGDTVTERSVTETSGAPMSVCDWRQIRTGFFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVL4</accession>
    <name>U1MVL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Micrococcal nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00149</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88008">
        <property type="protein sequence ID" value="ERG88008"/>
        <property type="gene ID" value="J07HX5_00149"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017188_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002071">
        <property type="entry name" value="Thermonucl_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01123">
        <property type="entry name" value="TNASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="1">
        <location>
            <begin position="39"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="447" mass="48156" checksum="F28DE1C0D0D05FC5" modified="2013-11-13" version="1">MTDTTHNVGSDYQPLTNEFNDGMFPVFDERDGLGLEVGKTFQATVTGVIDGDTIDVEFADGTTGEIRLLGIDTPETPKNVDYESVEEWEGIEDDNYLAKRGEVAADWATTELDGKVIDVFFDSKEPVRDPFGRLLAYVRYDADDGGGSRDTLYNQEAVQQGHARVYDSNMSKHDDFLMTELDARANGRGVWQRSDPSNSSEFRDRDVSEVFVPNASSVRTSTGTVADSRVPLFAAPTATQDLNGGVSYSTIPLAAVDEAVNTGLLGGLSISEEHDADSAAYEQFTFVTNLLNYLGDGSGEVLIDGGHGQFGHDHSLSAEDAVYYLRHLEGEGGVGFRGINRIDSAGLSGARALVVTPPTVPYTQSEVDAVSTFCSNGGALLLLGSSRTEDLFDEPRSLLNDIAAGVGSDLRLNEDRVLDDTNNVNNDPALLLTSNVNTAFPLFSKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVL9</accession>
    <name>U1MVL9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle 19 kDa protein</fullName>
            <shortName evidence="5">SRP19</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">srp19</name>
        <name evidence="7" type="ORF">J07HX5_00303</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SRP19 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88160">
        <property type="protein sequence ID" value="ERG88160"/>
        <property type="gene ID" value="J07HX5_00303"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_992478_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00305">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022938">
        <property type="entry name" value="SRP19_arc-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SSF69695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="DHFR" evidence="6">
        <location>
            <begin position="25"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="30701" checksum="9F9E41483D90EBC3" modified="2013-11-13" version="1">MSHDRTADHDTPTTHRVDGQVEDLRLIAVAAVAENGVIGSEGALPWPSLPADRHQYRARVADDPVALGRRTFEAMQANLPGTTQIVLSRSERHYAAESVFLVQTVVEALDQTRALGADRLYVLGGAAIYALFQPHIDRMVLSRVPGEYEGDAFYPEWDADAWTLVDRAPKMGSRSNSTGAVRDRGRVXXXXXXXXPAYLDAELSRNDGRRVGRELAVRDPSIDEIASAVQQVGYDAVIERDATYPREYEPRGRVLVKGAEDASRSDLLQATAAYVGALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVN8</accession>
    <name>U1MVN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00174</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88033">
        <property type="protein sequence ID" value="ERG88033"/>
        <property type="gene ID" value="J07HX5_00174"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172268_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="12827" checksum="F63AAC579D590004" modified="2013-11-13" version="1">MPNYRRDGLLATTALAVLLGVLLLEGTTEMLWRPIPAVAGVLGALVIEFGFLRYRSVPRWWDHSAVQFGGLVAVLVSGVVGYITVGAPVVVALCWGLVTYFLLLGAVLTVGHNPLAAIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW5</accession>
    <name>U1MVW5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00403</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88260">
        <property type="protein sequence ID" value="ERG88260"/>
        <property type="gene ID" value="J07HX5_00403"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_1_1_2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="312"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="249"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="420" mass="44104" checksum="DE303F8E4B7E75E0" modified="2013-11-13" version="1">MHVSIVGSGYVGTTVAAALADAGHRVTAIDVDPDVVEQLNAGESPIEEPGLEELVARYGGDELLGTTTFNRAADTALTLVAVPTPTGPEGAIDASYVASAVESLDRVVGDDHVIAVKSTVVPAALAAEIAPLVSGATLATNPEFLREGSALDDFQHPHKIVIGTDDADGRVSGLFEELYRPIVANTDPEPAVVHTGRDEAMLIKYANNAFLAAKISLINDIGNIAKLHGVDAYEVADAIGTDPRISDRFLRSGVGYGGSCFPKDVNALINTARDNGYEPTMLTAATALNDRQPDRLLELFDKHVDPAGERVAVLGLAFKPGTDDTRNSRAIPVIEGLQAREASVVGYDPVAQLDGHDLDIDHANSARAALAGASGAVVVTGWDEFAALDAAFNAMAEPVVVDGRRIIERREGITYEGLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVY0</accession>
    <name>U1MVY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00423</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88280">
        <property type="protein sequence ID" value="ERG88280"/>
        <property type="gene ID" value="J07HX5_00423"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712648_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7488" checksum="C9015B3A55924ACA" modified="2013-11-13" version="1">MARVSSQVRSNSDGLIVATWAGYRGDLERSGSRRPTATDHKNETRPSSPISAATDSTASGSVHSIVCLTAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVZ5</accession>
    <name>U1MVZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rad3-related DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00438</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88295">
        <property type="protein sequence ID" value="ERG88295"/>
        <property type="gene ID" value="J07HX5_00438"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_552772_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HELICc2" evidence="2">
        <location>
            <begin position="320"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="493" mass="53899" checksum="13BFC01DF64D5BF2" modified="2013-11-13" version="1">MSTTTGRPTNNRQPSARPRRCSSGSQTQARALSTDSLERAIAFTEWLIDTVGELVQTYLEDQYDYWTAAIGDGRPATDSFDLEDPAAPDTPDRLTQRLRQSDQFSPDYLQLFETVCTAAAAIHDETDISTRETACLEAGQTLARWHTADSVSHHREMVLEHSPHAQPPTQLPDWAKSITARLHLFNTIPSDRVAAIYDEVGGGIVMSATLTPLEEYKQTAGLAPLEQPATDNLAGTPPAGTPIGESPVDSRPVVTRTYDLAFPAQRRASWILDLPSYTKRNRGAPTQEWGQMTPTRKQYARALGEIAGSQGNHLVAMPNYAEAEWAGEWLDAQVDKPVYVDQSSGADETTALLGSFFQADHAVLITSSLGTVTEGIDYDGDKLHCATVVGVPYRNIATGRAQAIIESYDREVADGSQSGFDTAVGIPAVRKARQAIGRVIRGPAERGVRILLDERYAQTGKYGVGQYLSPAEAAEFRTIDSDMLSFGFEQFWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW24</accession>
    <name>U1MW24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glucan-protein synthase, RGP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00326</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88183">
        <property type="protein sequence ID" value="ERG88183"/>
        <property type="gene ID" value="J07HX5_00326"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061976_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037595">
        <property type="entry name" value="RGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31682">
        <property type="entry name" value="PTHR31682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03214">
        <property type="entry name" value="RGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="387" mass="43615" checksum="62F18CEA0F4CABE1" modified="2013-11-13" version="1">MQAEQDICVIMPTVREPECVRAYVENAQQHGVDTSRLFVLLVTEDFCDTDAMAAMLSSLEVNGAVFDGARREQWYSDRDIEAYAHLIPAASHAETSFGLLYMWANPRFEYGVFIDDDTRPHQEQNFFGRHLENLRHEGRITRVRSDTGWVNVLYQAADDHGLYPRGYPYSAMNETTETTRTHVEQGSVVASQGLWTNVPDLDAVRILTDGDLQGQAQTRLDSEALGRDFVAARGQYLTVCSMNLAFRREIIPVFYQLPMDDNQWDVGRFDDIWSGVFLKRACDVLGRQIYTGRPLCAHNKASRSTFDDLHNEAAGLELNEHLWRIVDEVGAGADSYAGVAAAIATRLQTADFEEYRNGAFLAQVGEYIDDWLACLDRLQPAPHATSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW82</accession>
    <name>U1MW82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00386</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88243">
        <property type="protein sequence ID" value="ERG88243"/>
        <property type="gene ID" value="J07HX5_00386"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090892_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="10"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18130" checksum="06E078BA87D18C71" modified="2013-11-13" version="1">MDQTRRQLLAGLGTAAGAAVAGCTSFLSGVGGGANGQFMLSTLDVGGSDGSTIPHRPAGEPALLDFFATWCPPCRPQMAELRVIDDRFSNLHMISISWEESASAIKGFWQELDGTWPVAQDTDLKIAQAYGVVGRLPTKILLDRTGEEQWRHTGLSGAASIAEKVTQVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWB2</accession>
    <name>U1MWB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00416</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88273">
        <property type="protein sequence ID" value="ERG88273"/>
        <property type="gene ID" value="J07HX5_00416"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089193_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="212" mass="23638" checksum="AD68C0A50E5D01E0" modified="2013-11-13" version="1" fragment="single">MLELEHGFRAIDAHIELEPDQTQRQPDASGPEEIERELRQAGVVRGFAFPAARSVEHLQANDGYLQANNAVARIAVDRSFRAIARVAGTRDPGAGPGTRLRNLGRSREDWQTTPDDIEQYAYEDRFVGFMIDPAADGLPQQAVLEQLAAVGRPVVTYGGRGFPPERIESTLLEYDFPLVIAHFGGYAMDRELIEAAIRLLNRHEQCFLDTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWC2</accession>
    <name>U1MWC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00555</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88410">
        <property type="protein sequence ID" value="ERG88410"/>
        <property type="gene ID" value="J07HX5_00555"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2727866_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7777" checksum="E976240F50BEA01A" modified="2013-11-13" version="1" fragment="single">MTDASPTAPTERVVALDALRGVALLGILVINVRVFAMPEVVLTNPTAYGDFSGLNYLVWLVGHLFAEQTFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWF1</accession>
    <name>U1MWF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein UspA related nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00452</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88308">
        <property type="protein sequence ID" value="ERG88308"/>
        <property type="gene ID" value="J07HX5_00452"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_11_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="15214" checksum="E017D8677277760C" modified="2013-11-13" version="1">MYDRLLAPTDGSSATQETLTHAFEMARRYDAAIHTLAVVDERQFYQLDGEQRYETQAALRQSAETAVERVADRATAGLAVTTAVREGHPSAQITEYAAANNIDVIVIGTHGRTGDDAIAPVGSVTERVVEAASMPVFVVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP2</accession>
    <name>U1MWP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00711</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88565">
        <property type="protein sequence ID" value="ERG88565"/>
        <property type="gene ID" value="J07HX5_00711"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1340700_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="204" mass="22506" checksum="1D4ACD9E66D9FA2B" modified="2013-11-13" version="1">MGLNSVRQPARSCITLSSLEAAVHSLRVGPLRSERDKIALLVPVVWPPAGRAHFWLGACGLEGVLDPGRRERCRWLRGECPDHQRSEHGVYAQVSRIDFVTGVSTGMRVAALPGLRAVRTTTMQPERGDTGPEKRPVVTVAVWLVANRYWVPELFCNRSNRLSERSTAVGERTEVAEPARTVDVDDCMEAVAGVELGRQRLATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWV9</accession>
    <name>U1MWV9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">o-succinylbenzoate synthase</fullName>
            <shortName evidence="4">OSB synthase</shortName>
            <shortName evidence="4">OSBS</shortName>
            <ecNumber evidence="4">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menC</name>
        <name evidence="7" type="ORF">J07HX5_00781</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88635">
        <property type="protein sequence ID" value="ERG88635"/>
        <property type="gene ID" value="J07HX5_00781"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_2_2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00470">
        <property type="entry name" value="MenC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010196">
        <property type="entry name" value="OSB_synthase_MenC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="6">
        <location>
            <begin position="128"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="341" mass="35076" checksum="3769CB5F93B65815" modified="2013-11-13" version="1">MLIEPYEIALATPMRTARGTIETRRGFVVRLSGPVGVGEAAPLPGWTESVADCRSALERCCEDSCDPVSTLDRLSAAATPAARHGLELAVVDARARAMDQPLYQWLGRTDDHTVPVPANATIVGGTTVETVTRAEAAVEAGYRAIKLKLGTGAVEKEIDKVSAVCRAVPDSVSVRGDANGAWSVAEATRVFAALDGRGVSYIEQPLSADELNAHRRLRKIGDVDVVLDETIRAVGLAAAVEAGAADGVVLKPMVVGGPRRAHAIARWAQAAGLTPVVTTTVDAAIARLGAIHLAASLSLTTACGLATGTRLAADIAPDPAPVSGGTVTPPSDPGHGVTIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX30</accession>
    <name>U1MX30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00684</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88538">
        <property type="protein sequence ID" value="ERG88538"/>
        <property type="gene ID" value="J07HX5_00684"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020819_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6295" checksum="66CC4710D2E6D031" modified="2013-11-13" version="1">MFTHPERLVCLHPTRRTVSRCGFRIDLQKTRGFRLRLYSTKSIKMFAAAAAAAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX84</accession>
    <name>U1MX84_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Permeases of the drug/metabolite transporter (DMT) superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00901</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88755">
        <property type="protein sequence ID" value="ERG88755"/>
        <property type="gene ID" value="J07HX5_00901"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="37"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="175"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="321" mass="33043" checksum="486D9E593F9CF8EE" modified="2013-11-13" version="1">MSTTANTSTGTGTDTDTETTTATPRVPPVAGLTVAVLGVSTGAILVRLSNAPSSVAAFYRVLFTTLPLLPVAVWRYRDAFGQISRRDVGFAVLSGLALAVHFITWFESLRWTSVAASVTLVQSQPLFVTAGAWLLLRERLTSRMILGILVAVVGMVAMSLGELRSGGVGANPLLGNGLAVIGALGAAAYVLAGRSLRQRVALIPYVVVVYTVCAATLLIIVTAQGGTAVLTGYPPREWLLFAGLAVGPGLLGHTVINWALGHLESSVVSVSLLGEPVGATVLAAVVFMEAPTATTIASGVVVLAGIYLTTVGSDDESAVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX96</accession>
    <name>U1MX96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-RFAP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00759</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88613">
        <property type="protein sequence ID" value="ERG88613"/>
        <property type="gene ID" value="J07HX5_00759"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1318488_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004422">
        <property type="entry name" value="RFAP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF6">
        <property type="entry name" value="PTHR20861:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00144">
        <property type="entry name" value="beta_RFAP_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="208" mass="21862" checksum="9A6B416657CD573F" modified="2013-11-13" version="1">MTIVETGARLHFGFQNLSLAHDRLYGGVGVGLASPTVVVEATPASTVQCDDPAVEPYARQAVEAVGVPGARVYVHERFDRHVGLGSGTQLALACLVAVAQTHDRAINPRVVAPAVGRGGRSGVGVATFETAGFVIDAGHPTERFTTAPPDTGEWRVPAPIVRRPLPASWRFVLVVPEAAPGLSGQGRLKVCTPPSRAPLRRLPTRLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXA6</accession>
    <name>U1MXA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type branched-chain amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00921</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88775">
        <property type="protein sequence ID" value="ERG88775"/>
        <property type="gene ID" value="J07HX5_00921"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="273" mass="30600" checksum="76342BDB1F2A10C3" modified="2013-11-13" version="1">MRDTKDTPPVVALDNAEIVYDRTFLAVQGVSLEAHRGEIVALLGPNGAGKSTILKMISGIGRTERGEVTRGSVSFEGEEVTNDKANKMVGRGVTHILEGRRVFEDLTVEENLRCGLYREGRRLRSHKDDYEIAFEYFPQLEDLLDVNAGYTSGGEQQMLVIARALIHRPNLLLLDEPSLGLAPQLVEDIFETMREINREEDITMIIADQNAKETLQIADHGYVLEGGQIELSGPAAELTDREEIKEFYLGGGSDSDESQYSDVRHYKIRKRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXC8</accession>
    <name>U1MXC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00794</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88648">
        <property type="protein sequence ID" value="ERG88648"/>
        <property type="gene ID" value="J07HX5_00794"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353116_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10573" checksum="23EB10C684B248B0" modified="2013-11-13" version="1">MIPTPALLVVLIGINLAGVGYGYYVGLKHVDRLLDIDEGQADPDFPPGFGARESERIGPLSADDIDGIDRWDQLRDRPEHQQNSASDEEQNRNSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXE2</accession>
    <name>U1MXE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00809</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88663">
        <property type="protein sequence ID" value="ERG88663"/>
        <property type="gene ID" value="J07HX5_00809"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544151_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="173" mass="19270" checksum="2EE8A0944F22C1B7" modified="2013-11-13" version="1">MIDETRIRCGRRHRLHNRCLSLQRHRLWTRLDQKGPEGQLARAAPDEGIPTVDPELGGSVGLDEASVQTGLDGVFNVLRHYEFLSGRTRTETQTRATGFEQYGSPAGGLIDFQVSLGERVERGRTLFEVTDVFGESKGTVTADSDGIFWRTRRRPQVASGEYVCSVGTNIDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXN4</accession>
    <name>U1MXN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00914</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88768">
        <property type="protein sequence ID" value="ERG88768"/>
        <property type="gene ID" value="J07HX5_00914"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954569_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="15039" checksum="34CC18F389077A3F" modified="2013-11-13" version="1">MRRREATIAITTAAIGLAGCSGSSDGGNTDAEADETESEQDAPQGEVVIEGQLSDAVSASSSAQFESGGADDNLVVDGTVTNESETETVRVTLQLQIEDFQRNASQTIELEPGTTEEYQLKLESIYTPQFAGYTVVVEAEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXR5</accession>
    <name>U1MXR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threonine dehydrogenase related Zn-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01077</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88930">
        <property type="protein sequence ID" value="ERG88930"/>
        <property type="gene ID" value="J07HX5_01077"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_9_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_zinc_N" evidence="2">
        <location>
            <begin position="158"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="333" mass="36190" checksum="30092BB6F0BF77A9" modified="2013-11-13" version="1">MGRSLVFTEPETVELHEEPDPDPDDDELIVRTEASAVSPGTELLVYQGNAPDEVVVDDELDAIGQDLSYPISYGYAAAGTVEQTGAAVDDDWLGESVFAFNPHESLFSADPESVLRVPDGISPEEAVLLPIVETAVNFLMDGTPRVGERAAVFGQGLVGLVTTALLAEFPLDQLVAVEPVEGRRRRARQLGADHVSSPGAVDELFDESGPGGADLTYELSGNPDALDDAIRLTGFDGRVFVGSWYGTKEAGLDLGGRFHRSRISIESSQVSTITPELRGRWDSQRRYQVAWDRLRSLPTETLITDEVPVEQAHKAYDRLSRNPGDCVGTVFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXX1</accession>
    <name>U1MXX1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0212 protein J07HX5_00994</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00994</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0212 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88848">
        <property type="protein sequence ID" value="ERG88848"/>
        <property type="gene ID" value="J07HX5_00994"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138334_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01223">
        <property type="entry name" value="UPF0212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007564">
        <property type="entry name" value="UPF0212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42199">
        <property type="entry name" value="PTHR42199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04475">
        <property type="entry name" value="DUF555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016934">
        <property type="entry name" value="UCP016934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12430" checksum="6CF557A1271A37D4" modified="2013-11-13" version="1">MDFTLVLEAAWLVRDVDNVDDAIGVAVSEAGKRLNQAEMDYVEVDVGFTECPACGEPFDSAYVAADTALVGLILEIEVFNVESEEHARRVAKSDVGGALRDVPLTTVDAIETGDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY02</accession>
    <name>U1MY02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MjaII restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01191</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89040">
        <property type="protein sequence ID" value="ERG89040"/>
        <property type="gene ID" value="J07HX5_01191"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089924_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019045">
        <property type="entry name" value="Restrct_endonuc_II_TdeIII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09520">
        <property type="entry name" value="RE_TdeIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="22949" checksum="99745CC986277036" modified="2013-11-13" version="1">MIGSLAIDIAELEYEVDQSVEGPMTTGQTNFIAELLESYKSGQKTPSVSDYQQLRSIYDGRETEHKRHESDYRLIDQQTGDRYLVELKIGGDLDNKKARSEKVALLEQYTILCNTLGDEDAHIRFGTAYNKDGEGNRWRQGRVRQYFAEDELLIGKEFWNFICNSETGYQDVLRAYQQNSYLIMDALESIKQTYLYDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY05</accession>
    <name>U1MY05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01196</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89045">
        <property type="protein sequence ID" value="ERG89045"/>
        <property type="gene ID" value="J07HX5_01196"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2459730_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046243">
        <property type="entry name" value="DUF6276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19792">
        <property type="entry name" value="DUF6276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="9421" checksum="3EAF30940E538AB3" modified="2013-11-13" version="1" fragment="single">VGTNPDHEPAIEQVSERFPTGDAAVPFALLVGLLENLALNRAAVTNLFATVEQAGVDPLARLEQLTHDPGLEPAIDLDGRARQLEQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY10</accession>
    <name>U1MY10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01039</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88893">
        <property type="protein sequence ID" value="ERG88893"/>
        <property type="gene ID" value="J07HX5_01039"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112918_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5304" checksum="F3BD9CE1F7C6EAE7" modified="2013-11-13" version="1">MRVADVTDATLLFASSQGGHLHTPCEWTDWEDCVQTTTVLARALAAAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY47</accession>
    <name>U1MY47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01085</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88938">
        <property type="protein sequence ID" value="ERG88938"/>
        <property type="gene ID" value="J07HX5_01085"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_578232_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="472" mass="49847" checksum="D0C9F55993F0E5B3" modified="2013-11-13" version="1">MGTLSRAGLVMIGLLIGLILVGAIGTFTATQTVLAAGFVTDAANEADAYSTAESALVEIAVDEIEGIDTAEIPTEAINTTAVVDSAIQETYIQNQSERLVRAGVGYLNGDRGTLNLTVNTQPLITDASAAAADAVRNVDLAVLVRDVTAEEIGTTATGVDVPVSGETLARMLEGPEEYRTVRQETRDEIRQTVIDQVIGDRTDREVLASAGVPDEQIKALSQAEREQLVEETIADATNINEQIADQRRAVRDEVAEIIRTETDRRTANYEANITQPAVELQLAVLDGIVTDQPYEQFTNRVENAQADIADEAEQVIQAEIESNLDTRVDLTDELSAENRDQIDQGAEITQLLPTAGVGLLGAIGLLTLIAFVISRSVPATATTTGSGLLGGGGLAALATTQDGRLTGPIERTFSEFNDEDVPVETAETFALIVVDGVSDQLLTYSLLAGVVGGVLVGAVVVRQIVFGVGDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYQ1</accession>
    <name>U1MYQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01458</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89300">
        <property type="protein sequence ID" value="ERG89300"/>
        <property type="gene ID" value="J07HX5_01458"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112920_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5431" checksum="0619397D77961175" modified="2013-11-13" version="1">MYRRQFMTAASGLLVWNGSRLAGSFVAEGGRLLGLMLTRTTTAQANRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYY1</accession>
    <name>U1MYY1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01518</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89360">
        <property type="protein sequence ID" value="ERG89360"/>
        <property type="gene ID" value="J07HX5_01518"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1323985_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="207" mass="22273" checksum="6BA96D6193BB46FC" modified="2013-11-13" version="1">MVGCEYCDESFETEAAYYEHLAAEHDDALSRIDRRKVSNYTTMSEDEKTIGVVDRLNTPVGYALLVTVATLGGLVLLFSVGSSGSNATPTPSNIGTVHDHGSLTMTVDGETVDFSQPQYQLQADAFHYEGGDGSEWHVHAEGVTLAWALETLDIGVTEQTVEYNGQSYTAGAPGTNVSVTVNGETVTPAEYVLQSGDQIRIEIQTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYY7</accession>
    <name>U1MYY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01528</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89370">
        <property type="protein sequence ID" value="ERG89370"/>
        <property type="gene ID" value="J07HX5_01528"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_576986_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="297"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="351"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="473" mass="51215" checksum="FFC946B762B258BF" modified="2013-11-13" version="1">MVGGTSIYFIFVLLGGLLPVALVPLALRNREMPGATGLLIYIPAATIHAISTGVESLEPSGATLLVVQSFVFLASALGSVGWFLIATDFTGYMRPTRRTLGVALGAVLLAPLLVLTNPIHQLLYAPGVEATADMAANRQPIYTVSVLCIYAPVLFGVGMIVLETVRAHGTRRKQGVVLLSSVIPPLIAVTISGTFEVVPMSLTPFGFIIGVGLLSLAIFRGEFLMISTTGRSQAIEQMTDPIIMLAQDNRVIDANPAARALFSAETDADAGWEGAHAAVFFGDAWAELSSIPEAGTTETELTVDTTDDGQRRSFDVNATRIADRTDVGHGTAITLREITDRKQTKRRLRRVTQRYDLALEGTSTGVWELEFEADTITLDERTHRLFGDPEQTITTYEGLLDRVHSDDIGAVKDAYTRAIEGKEPGVECRVRTADGWRWLALRGKTYTNDAXXXXXXXRPQILVLLLATLMGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ93</accession>
    <name>U1MZ93_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holliday junction resolvase Hjc</fullName>
            <shortName evidence="10">Hjc</shortName>
            <ecNumber evidence="10">3.1.21.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hjc</name>
        <name evidence="12" type="ORF">J07HX5_01685</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Holliday junction resolvase Hjc family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="10"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89520">
        <property type="protein sequence ID" value="ERG89520"/>
        <property type="gene ID" value="J07HX5_01685"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139546_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00523">
        <property type="entry name" value="archeal_HJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01490">
        <property type="entry name" value="HJ_Resolv_Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002732">
        <property type="entry name" value="Hjc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014428">
        <property type="entry name" value="Hjc_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39651">
        <property type="entry name" value="PTHR39651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01870">
        <property type="entry name" value="Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="121"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="183" mass="20103" checksum="5014E5A6C1BE481F" modified="2013-11-13" version="1">MSNAKGDRRERELVNKLDEAGFAVMRAPASGSATDRELPDVLAGDGGQFYAVEAKSSAGDPIYLDGEEVYALVYFAQNFGAKPRIGVRFDREDWYFFHPDELYQTDGGNYRVKKETAITDGTDFPELTGHSARTTLPEAAPSDSNGDEDEKEAPADGSRDVRRVLAAFEREDLSIDEAVGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZA6</accession>
    <name>U1MZA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Terminase-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01701</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89535">
        <property type="protein sequence ID" value="ERG89535"/>
        <property type="gene ID" value="J07HX5_01701"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1559419_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_6C" evidence="1">
        <location>
            <begin position="12"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18912" checksum="4CFC2142883D4027" modified="2013-11-13" version="1">MSAAESTGPYFIGADFARVEGWTVIVVLDAEGRIVAFKRLQQATWTRIQQTVERFADTYTPNAIALDATRDNKIVQDLEDGGYFVDPVRFSPSNKRTLVENLITDLEAGRITIPESANTLINEVEVYESRTSERGRVRYTAPSGFHDDCVDALALAVSAEDPTPRTIPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZD0</accession>
    <name>U1MZD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01551</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89393">
        <property type="protein sequence ID" value="ERG89393"/>
        <property type="gene ID" value="J07HX5_01551"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930081_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6948" checksum="73D19EB8C72B451D" modified="2013-11-13" version="1">MNKRVVDQTRSGDWSGQIIENPHDSNIAFYKHVGSIAQIQETQTELLEHFEQFGHEYTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZI6</accession>
    <name>U1MZI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01617</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89458">
        <property type="protein sequence ID" value="ERG89458"/>
        <property type="gene ID" value="J07HX5_01617"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="23"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="382" mass="41983" checksum="9FB56C15E66188FC" modified="2013-11-13" version="1">MTSSAPYEDADTGSRRGDTLLEIRDLKLYYTDGSLVGGEPPVKAVDGISFEIARGETLGLVGESGCGKSTLGRTLVGLRSVTEGAITVDGTAITELSGRELREWQQRIGMVFQDPQESLNDRQTVGEIINEPLKTHDWKTPAERESRIFTLLDQVGLKEEHFYRYPHQFSGGQRQRIGIARALALKPEFLVLDEPVSALDVSVQARVINLLERLQDELGLTYLFIAHDLSVVRHIADRVAVMYLGNLMEVGPTERVFESPANPYTRSLLSAIPGSSTPAPDDLDRITLRGTPPNPRHPPAGCPFATXXXXXXXPAQSVIDQATATAETDPEAALATVNTEFNSVCDRESPAEHSVDGTETSRTSRCLRHREEYQSPRNIGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZL9</accession>
    <name>U1MZL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01657</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89493">
        <property type="protein sequence ID" value="ERG89493"/>
        <property type="gene ID" value="J07HX5_01657"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1890010_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="134" mass="14902" checksum="100EB7A1F4E4BDA7" modified="2013-11-13" version="1" fragment="single">LAWQIEKFETPDSQLWIALDDCMDPTASIETTEATFAGFITTTLNFAPEAFAQPDRLVIGDFYVAPDYRGSGLADKLVARAAQAGRESGCSELALNVDVDNKRARAYYERLGFETARHRLRVPVSELALDLDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZN7</accession>
    <name>U1MZN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01678</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89513">
        <property type="protein sequence ID" value="ERG89513"/>
        <property type="gene ID" value="J07HX5_01678"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071765_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="29037" checksum="4100706BC3B2BBAB" modified="2013-11-13" version="1">MSWAAIARKDAREIRDSRLLRYLLYLVVIVYALAAYVYPIDRDPVTTSEFAGFATGSVELIVPLTAILLGYNAVVGERATGQLALSLSLPQSRRTVLVGKLIGRGGALAAALVAGLVVAAGLVVYPFGELEPLSYAGYGVVTLLLGGAYFAIAVGCSLVTASKQLATAAALGVFFLFVIVWDLVDDGLRVLFEQFGSASGELPAWALFLHGATPGQLYNRIVSGLFVGQETGTYLGPDTAWYLGEWVALGVLGLWTVVPILAGYWRFRRVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N046</accession>
    <name>U1N046_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01860</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89688">
        <property type="protein sequence ID" value="ERG89688"/>
        <property type="gene ID" value="J07HX5_01860"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_718876_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002749">
        <property type="entry name" value="DUF63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40700">
        <property type="entry name" value="PTHR40700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01889">
        <property type="entry name" value="DUF63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="391" mass="41996" checksum="4EC4EA35C8F4EB69" modified="2013-11-13" version="1">MDLLDRFNLRPETAWVVTFVTGVVVLAGASLAFTQRVFWGFLWQYFWGPIRADANGEACVGYVVEQDTVLSESGALTSCREAALAPEFGTVYLAEPGYTVVSTVGYISVLTFMLAGVYLLIDRINLQPYPRFFFALVPFMLFGGVLRTVEDAFVAALDQGITPAVEYPASALLISPVIYFVVFAVVIAALAGGKWLARSGRTTTFYYPLGVAGGVVLAGAFGYLLVLAATTEYVTLHADILAIVLGVATAAAVGAYLAVDRTRPVINAGTGLMGLVVIWGHAIDGAANVLANDWVDEIWSLGEYTPKHPFNEFIINTTTTLQGGQNVAGVYVGEAWPFFLLKIAVPVAFLTVFDEQFLDESPRYAILLLTAIVAVGLGPGTRDMVRIAFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N090</accession>
    <name>U1N090_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PPOX class putative F420-dependent enzyme, Rv0121 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01910</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89738">
        <property type="protein sequence ID" value="ERG89738"/>
        <property type="gene ID" value="J07HX5_01910"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1217537_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019967">
        <property type="entry name" value="F420-dep_enz_PPOX_Rv0121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03668">
        <property type="entry name" value="Rv0121_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="89"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="227" mass="24989" checksum="735A054900B74FC7" modified="2013-11-13" version="1">MASTKGPWGAEHSIHIHCLGVVERDAGVIGVFNSELLVLVDDATRSLEPSREQVKFGLSVAIGRRQTTRRQLLHSANHGSGMSTPWDRAERQYLETARVARLATVDPRGRPHAVPVCFAVDETRIVTPIDEKPKTEDPNALRRVTNIQTTPAVTLIADHYTETWDKLGWVQVRGTATVVSPTASSHRRAVAALRATYDQYADHALEQRPMIAIDPGQVISWGYLSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1N094</accession>
    <name>U1N094_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01915</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89743">
        <property type="protein sequence ID" value="ERG89743"/>
        <property type="gene ID" value="J07HX5_01915"/>
    </dbReference>
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        </location>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="126" mass="12997" checksum="242CF332A68E8DDB" modified="2013-11-13" version="1" fragment="single">MSVAPEPDDRTAAQLRWSGLFSFDDQRPAVTFTAAGEGTTGDPGTPDGGGPGPGSGDGDGDGDGDGFPIRIVALAGGLLMLGIGLGAGYRRWRTTPDQADALPHHEEDHTGDDSVSNPRKRSPTRL</sequence>
</entry>
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    <accession>U1N099</accession>
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                <person name="Narasingarao P."/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG89748.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="326" mass="35883" checksum="E0A1832795EFBE2F" modified="2013-11-13" version="1">MNEHRFLESDWDYAIVLDACRYDAFSRLYEEYLTGSLEKRKSPGSSTPEWAYRTFTGEHDIAYFSGNPFINSLGIPLNELKWGASCEYEWTATEHLGTVVDVWKDGWDESLGTVPPNSLARSMRAHQSVVADHDRTVLHYMQPHAPYLGRGDGRKLTKIRDGIKRQGDQAQTQVQTQTQEPIAADTATAGASTGGDTNTNTNTDTDARTNTGARTGGVLSAVGDRVRPAVESVLEDSSLAMKAGLFLELDTAEALRQGTRETALAYHEANLRIALESVAEIAEELDGQVVVTADHGEAFGEQGVWEHHIETHIPPLVEVPWLELAS</sequence>
</entry>
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    <accession>U1N0H5</accession>
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                <person name="Narasingarao P."/>
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</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </feature>
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            <dbReference type="EMBL" id="ERG88337.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="55" mass="6314" checksum="E83537F85D97C45C" modified="2013-11-13" version="1" fragment="single">MSFERSAQKEYLESEYGRYREQADAARTDGKPLTAAKYYSQCADVLEELAELETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4N0</accession>
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        <submittedName>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11444" checksum="F40BAE615683451B" modified="2013-11-13" version="1">MHAEVIADHAVAMQPGDAVIIDANPAAEDLVVALQAEIGRRGATSIPISRRMNKRARRAYLQAADGDLAAPTHEQVLIEVADVHLGIRAARNVTQMSDVPPAAATAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4P6</accession>
    <name>U1P4P6_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Copper chaperone</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88492">
        <property type="protein sequence ID" value="ERG88492"/>
        <property type="gene ID" value="J07HX5_00637"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_5_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7079" checksum="77927F0A3CFA9AF0" modified="2013-11-13" version="1">MSCMIDITVEGMSCSHCKQTVEDALQDVSGVTEVTVSREQKRATVNGDADATALVEAVENAGYTAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4Q1</accession>
    <name>U1P4Q1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00642</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88497">
        <property type="protein sequence ID" value="ERG88497"/>
        <property type="gene ID" value="J07HX5_00642"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1444636_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="187" mass="21537" checksum="FB1DA32E9FD67287" modified="2013-11-13" version="1">MFQLNIDEGEPLLLSEAFLESRRVFNETLRLDREDRDWGEIEDTVAKNANLVQNTAQRVVSKAQDALENYYNNDDWGRPWYHHDQFPLPMNYGEGYNLFLEDDAVRFRISAKPYNQVKGELRGSPDQFNRLEAAMTVTAGGLARLKPCGRIVDSSCTSQSRTNKPLFGRKPRVTPWLVWILTRIVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5L8</accession>
    <name>U1P5L8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00973</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88827">
        <property type="protein sequence ID" value="ERG88827"/>
        <property type="gene ID" value="J07HX5_00973"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032784_4_0_2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="365"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="408"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="439" mass="46756" checksum="7D7ABD4BF5C2C5FE" modified="2013-11-13" version="1">MTHDRVALAFSGGLDTTVCVPLLKEEYDHDEVIGVTVDVGQPAAELEEAAETADALGIEHHVLDATDAFAELCFDSVKANATXXXXXXXXCTGKGNDQLRFEAVWRGSDKAVVAPVRELGLTREWETAFAADHDLPVEGGDGGRYSVDSNLWTRSVEGSELEDPSTVPDESIYEWTQAPAGGDQSPASEQLTIQFEAGTPVALDGQSLNPVALIDQLNDQAGAHGIGRSDIMEDRMLGLKVRENYEHPAATVLLTAHEALEGLVLTQDERSFKQQVDQQWAEMAYQGLIAAPLVDALEGFIKTTNARLTGTVTVQLAGGTVRPVARESDASVYSERAASFDESDVASNIAQADATGVAKYHGFQSRLAEATPEQSTTLNTPSLTDGQTQTHTAAATGGDTDTDAGTDAGTDSTDRHDPSSPTENDPDPDTTREELMHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5V0</accession>
    <name>U1P5V0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01043</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88897">
        <property type="protein sequence ID" value="ERG88897"/>
        <property type="gene ID" value="J07HX5_01043"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447551_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9684" checksum="F1790C69E2DE119E" modified="2013-11-13" version="1">MWWPPVDDPGSYVVELTDECHAETAIVAIEAHATAVAPCVHPRLKLYQIGPHFRLESDVQAHSGDDACEADPTETGVTTPACRPGRYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5Y7</accession>
    <name>U1P5Y7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate uptake regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01100</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88952">
        <property type="protein sequence ID" value="ERG88952"/>
        <property type="gene ID" value="J07HX5_01100"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069302_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="340" mass="36904" checksum="3A959D276CC7BD84" modified="2013-11-13" version="1">MTHTPEDDTRLERKVQLTGGSTYTVSLPKKWAKQQGIEPGVMVDLHPRDGRLVVTQNRASDNLRQVTIQTAEHDEETLARAVGAAYVGGADEIVLEVADDTGDRRTATQAIRRFVGLEVMDEDEGALTARTMLDSPDLPPRRAVTQMRRTAVKMHSEAVAAVVAADGDQARRVGPEDDTVDRLFALVSRAFQRSLVDPATPVRRDSHSLFEHYTAARQLERVADHAEKMATIADQLASPPPVTLANAIESHGTASRAVVEDSLAGLLDGSSEGDLVGVIEDADSLLAEIDELDEQLYESERTTASYRLGGALNSILRTVKCGVNIAEAGLRADYRADSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P627</accession>
    <name>U1P627_9EURY</name>
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        <submittedName>
            <fullName evidence="2">ROS/MUCR transcriptional regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01152</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89002">
        <property type="protein sequence ID" value="ERG89002"/>
        <property type="gene ID" value="J07HX5_01152"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2283160_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041920">
        <property type="entry name" value="ROS/MUCR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008807">
        <property type="entry name" value="ROS_MUCR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05443">
        <property type="entry name" value="ROS_MUCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="11156" checksum="6907BBC6157697A6" modified="2013-11-13" version="1" fragment="single">ETAATAEADTEATIEVEDTTADTTVASADKHQRHAEAETETEPEADEETAAALEETGDTDETVTCRVCDQEYKAITEPHLQTHGMSTVEYRNEFGEDVPLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6H1</accession>
    <name>U1P6H1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01320</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89167">
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        <property type="gene ID" value="J07HX5_01320"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14741" checksum="EF1529F4F21E0BFC" modified="2013-11-13" version="1">MRATAVSGILLLFWGLVGLAGMVATVVLLGSGDLRAAAACLAPIAVFVPVLLVMVVPLKLTGHVLVTATTEYRVYDDTLIACDTRLAVAQWRFPLSEIVVLSIDDDSVTVETSAGERVLRHVADPDRLIETVERSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6K3</accession>
    <name>U1P6K3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01356</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89202">
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        <property type="gene ID" value="J07HX5_01356"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802057_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7045" checksum="BAF4C2F3D562FD3D" modified="2013-11-13" version="1">MSDGVVRYSHVSILARGVIAVSSIGSLDTAVAVIATRKTPDRTATNGETLKPTPDIARPCSGFSDWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6X9</accession>
    <name>U1P6X9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01485</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89327">
        <property type="protein sequence ID" value="ERG89327"/>
        <property type="gene ID" value="J07HX5_01485"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712651_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="8282" checksum="4017D7886EB5B08D" modified="2013-11-13" version="1">MDTRLRLTNVSCLGVKWFERHRLSSSRNKQSSVRLRGIRLVPPVEISAENAVYEKAVGMRCSRLEAQHTEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P714</accession>
    <name>U1P714_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sacchrp_dh_NADP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00042</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87901">
        <property type="protein sequence ID" value="ERG87901"/>
        <property type="gene ID" value="J07HX5_00042"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031002_4_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="10"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12430" checksum="EAC750CF4A0DCF43" modified="2013-11-13" version="1" fragment="single">MSGSERAYDVVVWGATGVAGRFVSEYLTEQYTPEELSLAVGGRDPERVESLATDLTRRSDAWADVPVVVGDATDPKSLRTLAGDTQVVCTTVGPYTSYGTPLVEACIEMGTDYCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P747</accession>
    <name>U1P747_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenite efflux pump ACR3 related permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01525</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89367">
        <property type="protein sequence ID" value="ERG89367"/>
        <property type="gene ID" value="J07HX5_01525"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="30874" checksum="6F97959061495768" modified="2013-11-13" version="1">MFGLAVVFFSGLVPGLPARPEFFLRLVFIGMARCIAMMLVWNELAEGSTEYVTGLVAFNSLFQIITYGVHVWFFGLVLPPLLGLETPVAGIKTFNVTSIQVPQAIAILLGIPFVGGVLTRYVGTRAKGEEWYDETLVPTVDPLTLVALLSTVVVMFATQAKNIVAAPSDVLLIAVPLTIYFVVMFFVSFGMGKGITADYSTTTAIGFTAASDNFELAIAAAVVVFGVGSGVAFTTVVGPLIEVPVLLALVSVALYFQRKFDWGGATTGQLNTSSAPPSAEEDRPTDQATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P783</accession>
    <name>U1P783_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00132</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87991">
        <property type="protein sequence ID" value="ERG87991"/>
        <property type="gene ID" value="J07HX5_00132"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2579196_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="8629" checksum="210A82013E142186" modified="2013-11-13" version="1" fragment="single">MTDAHSSTWIRLPRNVVLGRNVLEETADVVADLHLTGRPLVVTSPTPEAVAGERVTDQLAGIGPDPEVVVVDEASFAAIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P795</accession>
    <name>U1P795_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01580</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89422">
        <property type="protein sequence ID" value="ERG89422"/>
        <property type="gene ID" value="J07HX5_01580"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2269275_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11832" checksum="2DD7B43003C7160B" modified="2013-11-13" version="1" fragment="single">MSYSCDDRVGLCVDIDGTLYRRGSVFVEAASAFAVQSPVLERPARSQLREAIGLVGEFHGSAATRWRWKQTLRGLEGLRQHAGRQTAGQTFQLLQRLRRWLEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7A2</accession>
    <name>U1P7A2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01591</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89432">
        <property type="protein sequence ID" value="ERG89432"/>
        <property type="gene ID" value="J07HX5_01591"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_606365_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="451" mass="50271" checksum="F47F1279F318CD69" modified="2013-11-13" version="1">MAILDDLSGFEFEDLMEDVFRTLGYENVRQAARTADEGRDILMQEVVDGTRRAVIVECKHTGTVGRPVVQKLHSAVATFGFDGPKRGIVITTGRFTTPAQEYADGLQQSDNPHTIELLDGQALREIADEIGLDLYNGRIEILCDETLRPYDPAAGPDAPVREAFRDIENIDAEDIPAVFSRLTFRPVVTITADTDAVFETSVGVIHRVNDHTQVVAHAERGRPQVVDEAIATLVVDNVHATVEVAADRFGEVFDKVDERRFGQTQTEYKNWAVEQLQAYHTTTVTYTGDNNVTYTTTCEPNRSDIAVQSVGSVYLPEVRQTTELQEYTYPYECYVAGPSWVTTEDGIHRCVHCETSGTEESYTYCPNCGAIACDSHSKPERLAREPVCTGCAVTERFALKRKYFYDEDNLKTFRAEYADMPLHEKLMENEWLAAGIAVTVVVVLVAFVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7A6</accession>
    <name>U1P7A6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01596</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89437">
        <property type="protein sequence ID" value="ERG89437"/>
        <property type="gene ID" value="J07HX5_01596"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1329423_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="206" mass="23265" checksum="73895DC1AD2E3FAC" modified="2013-11-13" version="1">MIGLCSRYIMTPQQRADNTTSDGLQHGAQSEHPDATAKTRHHDNQTATRSDETASEVRFLPDQDVELFYRHAQRKYALADSFTLDDDMVKNNLDDLLLALVAHREAETNGKELRRDLATLFNSHLSPGTVYPSLHDLDESDLLDIHELVQTKEYDIADTESVVEQLERAMRQHLVLGDLLRQAVAEINEQATQTDESDGVDIPSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7D6</accession>
    <name>U1P7D6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00192</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88051">
        <property type="protein sequence ID" value="ERG88051"/>
        <property type="gene ID" value="J07HX5_00192"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447546_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="PTHR19248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9767" checksum="CBBEA7755A51E1EA" modified="2013-11-13" version="1">MGSTLYRLPASQDGRITGTLGPNAIGKTALVRILARELAPNSGYTNETPSWDRVIGSYRSTKPYNYLIPVRDGAVQVAREPQYVDRMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7E4</accession>
    <name>U1P7E4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00202</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88061.1"/>
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        <property type="gene ID" value="J07HX5_00202"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="322" mass="35274" checksum="4725CF1C6622903B" modified="2013-11-13" version="1">MLVFFYPNQRVLARAGTIRLMQDARVLVTGGAGFIGATLANYLVKTNEVIALDDRTLGTPENLDPGVRFVEASVLDDDWPAAVDVVFHLAALSSRSMLEERPQAGTRVNVEGLVNVIERTREHAESVVFAGTSSMYNDDLPASEDDRVAAATCYEASMLARDRYMEYYNAFYDDLTVASTRFSSVYQGYGGNEAHKGEYANTVSQWAAKMANGDRPVLWGDGTQTRDYVHVTDVARALEAVADAQLAGAYNVGAGRNVSFNETIALLNAALGTSIEPTYEPVPLTNYNYQQRFDISKLQAATGWEPTVSFEDGVEQVCAPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7N8</accession>
    <name>U1P7N8_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Putative endonuclease containing a URI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01738</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89572">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="11097" checksum="5CBBAF744EBAFFFB" modified="2013-11-13" version="1">MSEAGQYVYVVECSDGTLYTGYTTDVARRVAEHNAGEGAKYTTGRRPVTLRYVELHNSRSAAQRREHEIKARSRAQKDQLVPATTDRVAVAFAHTVSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7P9</accession>
    <name>U1P7P9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88166">
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        <property type="gene ID" value="J07HX5_00309"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4410" checksum="E25B13627B3740DF" modified="2013-11-13" version="1">MELKXXXXXXXIYALLRYFETHGEVDGRLPGVGRVPKAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7U7</accession>
    <name>U1P7U7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ParG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00364</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88221">
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        <property type="gene ID" value="J07HX5_00364"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3194408_0_0_2"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015354">
        <property type="entry name" value="DNA_partition_ParG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09274">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="45" mass="5256" checksum="F55249C0F78EB65E" modified="2013-11-13" version="1">MTKRLSVDFEDDVYKEFSKKCIEVGETKSDVVRGLVTDWLNESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7X2</accession>
    <name>U1P7X2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01833</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89662">
        <property type="protein sequence ID" value="ERG89662"/>
        <property type="gene ID" value="J07HX5_01833"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109676_0_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
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    </dbReference>
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        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="112"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="213" mass="23131" checksum="992B01AC473C3188" modified="2013-11-13" version="1">MVSISTMTDEADVDQSKRATLRRFAALGAASPLIGLAGASKSESDTPEAIVGYLSATPGAHFSKLRDDLKLGTGETQHHLRQLESEAMIESGKDGDYRRYFPAGRFDTFQQTALGALRRETPRRMLIALFEGTHSPAAIADQIGVSRPTISRHTAELEDSGLLVREPVYRVVDPETVLLLVVRYADSFGAAAARLASRAPDLLEYTPESTPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P819</accession>
    <name>U1P819_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00434</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88291">
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        <property type="gene ID" value="J07HX5_00434"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143268_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15888" checksum="0A71B723CC3CBA4E" modified="2013-11-13" version="1">MNLASLRDNPVIAALLGVAITGLGHLYLRRWLRALGWLAGAVTVGILFVPESAIEAVRSGTFSDPLAILPVVVVSAASVIDAYLIARTNTRAETGQTTDTSDAEEDLLDCPACGKPVEPEMGFCHWCTTEFEVVNDTELRRLDEDGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P872</accession>
    <name>U1P872_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01929</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89757">
        <property type="protein sequence ID" value="ERG89757"/>
        <property type="gene ID" value="J07HX5_01929"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3130711_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5707" checksum="F8B435B6EEF0F4AB" modified="2013-11-13" version="1">MQEVVAFPFDCLMTFSHFLSLLFPVGWTVFLPRKFALFTLESITFFGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8B8</accession>
    <name>U1P8B8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease NucS</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nucS</name>
        <name evidence="3" type="ORF">J07HX5_01974</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NucS endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89802">
        <property type="protein sequence ID" value="ERG89802"/>
        <property type="gene ID" value="J07HX5_01974"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069350_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00722">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002793">
        <property type="entry name" value="Endonuclease_NucS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38814">
        <property type="entry name" value="PTHR38814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01939">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="26038" checksum="77E5D4765AD9A52D" modified="2013-11-13" version="1">MTDSPRTLLQPTAAAAIGLVDDALSADQLVTLVGRCRVVYEGRATSTLGPGDRLVVRKPDGTMLVHTDEGHQPVNWQPPGSSCDCRLADSGVVLESKHENPSEELIIRFETITHAATFDPNDPNELALSGTESDLRDQILESPSLVEPGFEPRATERKTSAGAIDIYGEDTDGRAVVLELKRRRAGPDAVSQLNRYVDALTRERHADATVRGILVAPSVTDRAHRLLAERGLGFVSLSPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8F6</accession>
    <name>U1P8F6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00541</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88396">
        <property type="protein sequence ID" value="ERG88396"/>
        <property type="gene ID" value="J07HX5_00541"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1335017_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="205" mass="23289" checksum="FB285E417A5C0442" modified="2013-11-13" version="1">MAIEVTRTYVGSIQNHPQVCDGLDSLGDSASKIWNVARWTADRVWDTTGEIPDAGVLKSYMKNQACWKDLNAQSSQKVIEELSDAFQSWFELRHKDDEANPPGYRKHGDTRPRSTVTFKEDGFKHDPENNRIRLSKGSNLKEYWADFXXXXXXXTTRRSRSRIRAGRQMITATPDGVCCARRGSTDTSRLLSTRSRCIAPRANTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8T2</accession>
    <name>U1P8T2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-ribbon containing protein (DUF2072)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00692</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88546">
        <property type="protein sequence ID" value="ERG88546"/>
        <property type="gene ID" value="J07HX5_00692"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063606_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018645">
        <property type="entry name" value="DUF2072"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09845">
        <property type="entry name" value="DUF2072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="203" mass="21615" checksum="D7F43B0BB7232533" modified="2013-11-13" version="1" fragment="single">MPHRCTSCGQSFDDGSKEMLSGCPQCGGTTFQFHPDGADPAEMSPPAETAPPEPPGSSVTKTVGSAATTIKELFGTNDNGSSTTPGEHSGMGAATDTDRGSPDGSQSTETRSAETPGENSAQASARGDPIETLPPAPDDESIDETHRFDPPIDDETDQPAEEQQDRPGLSELREELNDQFESIKVLQPGQYELNLMELYNREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAL5</accession>
    <name>U1PAL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01294</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89141">
        <property type="protein sequence ID" value="ERG89141"/>
        <property type="gene ID" value="J07HX5_01294"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3322819_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="38" mass="4380" checksum="CD6EB8DDAFE0227D" modified="2013-11-13" version="1">MSSYLRTETRTHGVRPETVDQLPASAREAAQYPWVYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAV6</accession>
    <name>U1PAV6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">J07HX5_01386</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89231">
        <property type="protein sequence ID" value="ERG89231"/>
        <property type="gene ID" value="J07HX5_01386"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_3_1_2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="51"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="150"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="333" mass="35925" checksum="03A6CB781C667047" modified="2013-11-13" version="1">MASEGTFAGYGGRHVPEPLEEPLAQLASEFEAAVASESFHEELEHLLEHFGGRPTPVFYAETLSERYDADIYFKHEDLLHGGAHKLNNTLGQGLLAQRTGSERLIAETGAGQHGTATAMVGALLDLDTTIYMGKTDIQRQEMXXXXXXXSVIGREAREQIQQLHGDLPDACVACVGGGSNSIGLFDAFRDDAVEFYGAEPAGEGLNSGQHSAPLSQTEQDPQIFQGMKTQVIDEETENHSVSAGLDYPAVGPEHAALQELGRAEYHGITDDEALAAFREVSEAEGIIPALEPSHALALAFKLADEDRHDTILINMCGRGDKDMQTAAEKFDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBL2</accession>
    <name>U1PBL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxycytidine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01620</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89461">
        <property type="protein sequence ID" value="ERG89461"/>
        <property type="gene ID" value="J07HX5_01620"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103451_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15439" checksum="BC2628BB082B9526" modified="2013-11-13" version="1" fragment="single">MFKSGQFVAEQLGELGPAQLQPNGVDLTIADVFEQVGTGRIEQSGTTIGDRRAVSPTDGLYRLASGAYIIQYAERVTIPEDHVGYIHPRSSLLRNSCMLETAVWDAGYEGRGEGLLEVYAEIELEPGARIGQLVLAQAANEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC62</accession>
    <name>U1PC62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative cation membrane transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01853</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89681">
        <property type="protein sequence ID" value="ERG89681"/>
        <property type="gene ID" value="J07HX5_01853"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133067_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="12793" checksum="8F52D2D57090AA22" modified="2013-11-13" version="1">MFENCLSAASPTTSMQSYLALVGAILAEVTGTTLLKLSDGFDNAAFGVGAMALYLIAFYFVSEALADLPVGLVYATWSAVGILALAVIGVTVFRESVDAAGLAGFVLIVAGVVLLNVYSTAYSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCL0</accession>
    <name>U1PCL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01998</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89826">
        <property type="protein sequence ID" value="ERG89826"/>
        <property type="gene ID" value="J07HX5_01998"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2366094_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036361">
        <property type="term" value="F:racemase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10061" checksum="375F00B04B9EF6D2" modified="2013-11-13" version="1">MTADARAAAGIDTVGVLGTKPVMSEGFYQDRLADHGIDVVVPGPPAQTVVDKIIFEELTYGVVREASRGTYREVIDELTTAGAEGSYSAARRLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCS8</accession>
    <name>U1PCS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor 2, beta subunit (EIF-2beta)/eIF-5 N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_02058</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89886">
        <property type="protein sequence ID" value="ERG89886"/>
        <property type="gene ID" value="J07HX5_02058"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="PTHR23001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="SSF100966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="SSF75689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eIF2B_5" evidence="4">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00653"/>
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        </source>
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    <sequence length="132" mass="14604" checksum="03527F4A5669B916" modified="2013-11-13" version="1">MDYDEMLERGMEAAPDIAGDTDRFEVSTPDVRQEGNMTVFENFQAIRDELDRDEDHLMKSLQTELGTSGHIDESGRARLTGDFGTDRIDEAVDAYTEQYVLCSECGLPDTAIEREQDAEILACAACGARSAT</sequence>
</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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</entry>
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    <accession>U1MFY1</accession>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88129.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG56</accession>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13410" checksum="06BE7799CC5A8CDC" modified="2013-11-13" version="1" fragment="single">MSQHHNHTDRSTRRRFLVTAGATSLLGLAGCLSDDTADTPGSTVGQIGSGREGRTLPGGTPVAELPALSGELTLYSGRSEFLVGDLLAFIENQYDEFSITPRYGSSTDLVNQVLNEGSGSPADVFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG65</accession>
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        <submittedName>
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        <name evidence="2" type="ORF">J07HX5_00337</name>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="1">
        <location>
            <begin position="41"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="328" mass="33027" checksum="25CFF8C9B1F4E0D7" modified="2013-11-13" version="1">MNIVDDCSNSSFLIVCAHHNAEVTEPVXXXXXXXVALAAGAVPGWTHAAPYEGTRNVAVAAATALATVGASPLAAVNCLNAGNPETAAVFGEFEAAVNGLADACRNLDVPVVGGNVSLYNDSAAGPVPPTPTVVMLGRGSGNHTAPPPIEGDGSLLLIGGHTDALGGSTYLSQFGGTDAVPTPPAALTERLATLSAITKRPSTQTVASVADGGLAATLARLVAGENEQLAGAPAGSSRAASARVSVPGVPSLLSEAVGRAIVETTDPDSVRAAFDDHTQVTELGETTAVHEDESDEEAELTVTVGDRSLRYSADELGTLRATLGRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG90</accession>
    <name>U1MG90_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidophosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00367</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88224">
        <property type="protein sequence ID" value="ERG88224"/>
        <property type="gene ID" value="J07HX5_00367"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_3_1_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="29"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="484" mass="51367" checksum="7B08158EE901E042" modified="2013-11-13" version="1" fragment="single">MDPDARPRDDQSTSQPGTDNQPSTPREKCGVVGVSRRGDAAAFPLYYGLYALQHRGQESAGIVTHDGFQQHEHVGMGLVGEAFDEADLDRLAGGTGIGHVRYPTAGSVDKSCAQPFSVSFRGGALGLSHNGNLVNAAAVRSELAAGGHAFTSDGDTEVIAHDLARNLLEADLVAAVRQTADRIHGSYALAVMHDDVVFGLRDPVGNRPLVLGEIDGGYMLASESAAVDAVGGELVRDVNPGELVVLEPNGAGISSHQLFNREHTAHCFFEYVYFARPDSVIDGQLVYDVRRELGRRLWTETGVDSDVVVPVPDSGRAFASGYAAAADGVQFAEGLMKNRYVGRTFIMPTQEDREQAVRLKLNPIQSTVEDKSVTLVDDSIVRGTTSDRLVELVRDAGATEVHIRIGAPPIAAPCYFGIDMASREELIAADQDSAAIADTIGADSVAFLSPDAVASTLGAAHDDLCMGCVTGEYPFDVDGEATDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG99</accession>
    <name>U1MG99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00377</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88234">
        <property type="protein sequence ID" value="ERG88234"/>
        <property type="gene ID" value="J07HX5_00377"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1172760_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="25257" checksum="F3E25EDA1AD3C6DC" modified="2013-11-13" version="1" fragment="single">FLSTGPVDRVQRPVKLIVANERALAAGTRYVDADLNRLFPGVPDSDVHEEQLAHALHNKIEDCMTLGIHATVSFAEPFGTLADPTPLKTDLMRALPVDYAADFSGVVEGRSVNLGQFINVEAGYQGSASAVENAYGCLLAYLRATDVLPGATDPTPTVHYRVDEPIRKAPDQSYEVCAENFDRVPSGEAYAVSAAGGQLTADEPFWPVLLSADGHETLLGYRARRVGTLGDTAGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGH4</accession>
    <name>U1MGH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Orc1/cdc6 family replication initiation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00458</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88314">
        <property type="protein sequence ID" value="ERG88314"/>
        <property type="gene ID" value="J07HX5_00458"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1736359_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc6_C" evidence="3">
        <location>
            <begin position="70"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="169" mass="18822" checksum="2A9CB098F05D139B" modified="2013-11-13" version="1">MISLCAALAAQDSGSARQALNLLYNAGELARADGDSKITETHVHDARDELEQSQIEHGMRELTRHGHLALVATLTLALDGETPARVREIYPRYRTIADQSSIDPLVRRRMHDHLADLAMLGILDRHSRNEGRSGGQYYEYEFAVDLGIVQKVVGDLEGVVLPERVLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGJ1</accession>
    <name>U1MGJ1_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00478</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88334.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88334">
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        <property type="gene ID" value="J07HX5_00478"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0006508">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11875" checksum="D729F8E510A4130A" modified="2013-11-13" version="1" fragment="single">MTVGEGARTALLFGAPHPNELIGSMTIDFLLHELADNDELRASLDYTFVCMPVADPDGVEKNEGWFDGPFTLANYAANFYRPPPHTQVEATFPVEREQYAFDDPIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGV3</accession>
    <name>U1MGV3_9EURY</name>
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        <submittedName>
            <fullName evidence="4">SPFH domain, Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00609</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="29"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="353" mass="39370" checksum="E66CA86E88F6AA86" modified="2013-11-13" version="1">MRFLLQTGTTTLGIVGAVILGIAAVAVWQAVVLVNAYERRALTIFGKYRRLLQPGLTIVPPFVSKTYTFDMRTQTIDVPQQEAITRDNSPVTADAVVYIRVMNAEKAFLEVEEYKKAVSNLAQTTLRAVLGDMELDDTLSKRAEINARIRKELDEPTDEWGIRVESVEVREVTPSREVKTAMEKQTGAERRRRAMILEAQGERRSSIEEAQGDKQSNVIRAQGEKQSQILEAQGDAISTVLRAKSAESMGERAVIERGMETLEEVGKGESNTFVMPQELTSLVSRYGKHLQGNDTGSAKQNGHTLEGLEFDDETREMLGLDDIEQILGELELEEDTEISEIEDAEEIPDPEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIB5</accession>
    <name>U1MIB5_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01277</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89124">
        <property type="protein sequence ID" value="ERG89124"/>
        <property type="gene ID" value="J07HX5_01277"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020861_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="56" mass="6388" checksum="EA020551E3206D6C" modified="2013-11-13" version="1">MESVRKGLRVGTVEKDNYGRLRCTECETELTTSNNPEKVGKVRICPSCEQEWKELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIC6</accession>
    <name>U1MIC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formyltetrahydrofolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01292</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89139">
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        <property type="gene ID" value="J07HX5_01292"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2067718_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0008864">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="13109" checksum="070E79606E2EDDA1" modified="2013-11-13" version="1">MTRSDTEITVVGDDDTGLIAAVTSLLFERSVNIEDLDQAVRDGVFRMTMRVDTSEMVTTRETLRNDLQALAAELGVDIQVRFPADRETSQIAVLVTKTSHCLRQSWKQATXXXXXXXG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIF4</accession>
    <name>U1MIF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01327</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89174">
        <property type="protein sequence ID" value="ERG89174"/>
        <property type="gene ID" value="J07HX5_01327"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2392778_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="93" mass="9387" checksum="315057A936484780" modified="2013-11-13" version="1">MLRGRGIPLTSFLVVAHSAPKSLVVVGAGPDALATDGRSSDRRVPSALPCLGDYRVTGPVISRKTAIAAGPDGSVTVSTLISIGICSPLSVTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIZ7</accession>
    <name>U1MIZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01557</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89399">
        <property type="protein sequence ID" value="ERG89399"/>
        <property type="gene ID" value="J07HX5_01557"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243734_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="10911" checksum="D8A8992997BA6FE1" modified="2013-11-13" version="1">MEFRRGVSEMFLLFSLVHANGYPAALFPNPHYSGARSTHSLVGSSVGADLACSRPNRGDPLCLALAQMISAAGTALAIGVSLRAVTTIRLLAGTASRGPRQTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJU1</accession>
    <name>U1MJU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01941</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89769">
        <property type="protein sequence ID" value="ERG89769"/>
        <property type="gene ID" value="J07HX5_01941"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2202377_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="12095" checksum="12165186442B4790" modified="2013-11-13" version="1" fragment="single">YALWEFGRTEEALEHAERAVEIDPRFGQAWYNRGFFLNERGLAGEALAAFDNAVRLGYRSADLLEEKAIALESVGEDERAEEVAEEAEELRSSNEQTLIDDETGLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK92</accession>
    <name>U1MK92_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02152</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89979">
        <property type="protein sequence ID" value="ERG89979"/>
        <property type="gene ID" value="J07HX5_02152"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170076_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="10569" checksum="EB505CBE8C572215" modified="2013-11-13" version="1">MTPVDPQQAQPSDEEATAVLMFPYSTTSAAQRVANAIAPETNALDDARSQVTLARDNQTVELRVHATDRTALRASLNTWFKLVEVAEHAGDATSTASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV91</accession>
    <name>U1MV91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00156</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88015">
        <property type="protein sequence ID" value="ERG88015"/>
        <property type="gene ID" value="J07HX5_00156"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074816_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010768">
        <property type="entry name" value="GATase1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07090">
        <property type="entry name" value="GATase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase1_like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="249" mass="27313" checksum="6A03FBF378DDD241" modified="2013-11-13" version="1">MDVLYIGDYKLQTSQFYVGADTFQQFHRKIKDYEPLLDALNAMPNVNPTFLDGPDTMTEFPRSAEQLHEYDALLISDLSRGTLEPHFFEDAIPGPNLLRVIRRYVESGGGLVYGGGWMTYQGYQGVGNWQGTPVEDVLPVEIQPVYDDRVERPEGASPKLLDETHPLLSEIGQSGLPTVYGYNEVAEFSPGVDAIATIDGHPLLAAGMFDEGKSVAYTSDPVSNGARDVDWTATKRLAYACGGSLTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVB4</accession>
    <name>U1MVB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00029</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87888">
        <property type="protein sequence ID" value="ERG87888"/>
        <property type="gene ID" value="J07HX5_00029"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2230275_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="10619" checksum="6D59EE17BDD90EBB" modified="2013-11-13" version="1">MTERSSSSHADVPEAQQRGNCNRKTVTPDHPGPAGPAHVLDRADDAATTDGGRTRLSADWTAGHASCVAGSASAAGVIRASRIAFPVTAVVMPASPARTASQIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVH3</accession>
    <name>U1MVH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00253</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88110">
        <property type="protein sequence ID" value="ERG88110"/>
        <property type="gene ID" value="J07HX5_00253"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2190939_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11473" checksum="54094DF88D286D9A" modified="2013-11-13" version="1">MTPEENSATASQDTATDVETVTGAHPGGPQHQQPPFPAVANAVRTVVAGDASGHGMAHAWRMFRLTQQFVATLDADRTIVGCVALVHRDFEADTPRLDLGEEADGHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW10</accession>
    <name>U1MW10_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase Hel308</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hel308</name>
        <name evidence="7" type="ORF">J07HX5_00454</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. Hel308 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88310">
        <property type="protein sequence ID" value="ERG88310"/>
        <property type="gene ID" value="J07HX5_00454"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006553_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Helicase_Hel308"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2 3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="34"/>
            <end position="199"/>
        </location>
    </feature>
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        <location>
            <begin position="233"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="700"/>
            <end position="753"/>
        </location>
    </feature>
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        <location>
            <begin position="729"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="753" mass="81734" checksum="F7F84129A6C2C464" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW14</accession>
    <name>U1MW14_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00316</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88173">
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        <property type="gene ID" value="J07HX5_00316"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1492935_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19773" checksum="62406386640287BB" modified="2013-11-13" version="1">MSVSFIYADKPRGIRLGPALPSSYPPTPEAVGFRLVSVEMTWWRRGHTVQNASSVYCVAGVRSSGDCGRRLRRRWLNVRTRSDLLHIDSAGATPVVHRVSSFRRPAGQDSRTRRPQTDCRTRSTGSKHRLEQATRRSPVTGVSPWFARGVGRGVTCAGVSTYTRHPDGALLGMAAHTDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW48</accession>
    <name>U1MW48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00489</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="16489" checksum="E9CC6917EEFB26B6" modified="2013-11-13" version="1" fragment="single">MVAGNQRGLADAIRYDVQILHESWMELFFPRQRGVSDTVLGKWSPESPREQITYTAWSTLGVPVIALLYPLLLTGYFIRFQARRLAATAVRLGLLGVIVLFVLLWGGLVAVVWLQFSGSFTDVEIVAIATAGGAATFASVLSYATARAAGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWC5</accession>
    <name>U1MWC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exonuclease VII, large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00426</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88283">
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        <property type="gene ID" value="J07HX5_00426"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_968397_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="3">
        <location>
            <begin position="2"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="287" mass="30897" checksum="460E585B64511123" modified="2013-11-13" version="1">MTERSPRTTVSLYGASVQGEGAVSAVVTGVQALDADPTVETIVITRGGGADVTLTTFDAEPLVRAVAACSTPTVVAIGHEDDQSLAERAADARAMTPTEAGVVATPVITDTLETLAVTERRIASAYETLVDRRLTGLGRRVEAGVDRLRQRRQQQASLRQRAEDLERRIDTAYRTAVTDRLGALETRIEHGLRTTELLAQDERATARVVRGRVAGLEARIETAYRARVERELQTTAGRLTDAYRDVEAAEQIATHRAENTRLRVVVVALVVVLGLVLLVGVALVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWC6</accession>
    <name>U1MWC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell division protein 48 (CDC48), N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00560</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88415">
        <property type="protein sequence ID" value="ERG88415"/>
        <property type="gene ID" value="J07HX5_00560"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1630445_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="SSF54585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48_2" evidence="1">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="17076" checksum="CE7C0E56DA0C643E" modified="2013-11-13" version="1" fragment="single">MSENITVRVEGARKADAGRGIARLPPRVQNQLGILSGDPVIIEGTSLTVAKVWPGDDDGPVIRIDADTRASVGANIGDTVQVRNASVETAEAVTLRPADDHADTTPAAAAISRKLVDRLVREGKQLRIDGYGGYVVTETVPNGSVRLTDATTVTVEPEPATPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWM5</accession>
    <name>U1MWM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00691</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88545">
        <property type="protein sequence ID" value="ERG88545"/>
        <property type="gene ID" value="J07HX5_00691"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145183_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012017">
        <property type="entry name" value="UCP004977"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09846">
        <property type="entry name" value="DUF2073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004977">
        <property type="entry name" value="UCP004977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="126" mass="14022" checksum="A44E520A3337B57C" modified="2013-11-13" version="1">MPEAKQRDGVRIDLISAERMANMASMEKIRMILDGVRDGNIVILEEGLAPKEESKLIEVTMTEITPEGFNGIEIETYPQDQTESTGFLGRLVGNDSPNKLTVVGPANRIETLHKDEQLIQTLVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWS8</accession>
    <name>U1MWS8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00573</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88428">
        <property type="protein sequence ID" value="ERG88428"/>
        <property type="gene ID" value="J07HX5_00573"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3407242_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="30" mass="3185" checksum="6D57A2AFC8C043B4" modified="2013-11-13" version="1" fragment="single">MLPAPRTEEPRSGSELRLEPIEMSAASAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXN9</accession>
    <name>U1MXN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01046</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88900">
        <property type="protein sequence ID" value="ERG88900"/>
        <property type="gene ID" value="J07HX5_01046"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035990_6_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="26244" checksum="32E90F2270B7C296" modified="2013-11-13" version="1">MCGRYSLFVPPNRLSSRFDVSSGGYEPRYNAAPGQSLPVITDAAPDRLSAVEWGLVPPWADDRSDGHINARAETVTDRPSFRDAFEQTAGGRCLVPADGFYEWTDQNGATQPYRVTRTDETAFAMAGLWSRFEPTTTQTGLDAFAGGEVDEPEPIETFTIVTTEPNSLVEQLHHRMAVILPTDAETEWLTASPERAEKLLEPIPGATLKTYPVSTAVNDPANDSPAVVEPVTDEQGESLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXS5</accession>
    <name>U1MXS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01087</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88940">
        <property type="protein sequence ID" value="ERG88940"/>
        <property type="gene ID" value="J07HX5_01087"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155668_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIB" evidence="1">
        <location>
            <begin position="18"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="93" mass="10168" checksum="34EB363F58FD9198" modified="2013-11-13" version="1" fragment="single">MYRARDELAHEEWLDRLEAAADELGLGVDARSRARDIFLAAVPDRRRSKPAAVAASLYAGALLASDRRSQAAVAEAAGVARLTVHNRWQDQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXV7</accession>
    <name>U1MXV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00989</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88843">
        <property type="protein sequence ID" value="ERG88843"/>
        <property type="gene ID" value="J07HX5_00989"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1307786_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="210" mass="21312" checksum="FF46AD10F1511D45" modified="2013-11-13" version="1">MEYRDTLTGGAYGIVVGGLAFVGSTAGIVLVLAVTGGNADAELLRLLERTEGTGELFDALRPTALEAVSWQVLTSHLVPPAVEITLAGQSVTSSALRPSTGLWYYTIPVVMLVAMGAVSGVLSQRTRLTRGVTTTAVAGAAITLGYLPGVVAVTLIGEFSVSPGLLIGVSVTPDMPPTIVIAGIVYPAVCGTVGGALSYLLYHAPTQAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXX8</accession>
    <name>U1MXX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01160</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89010.1"/>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_01160"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="19919" checksum="2CCEF51A0E3F6D15" modified="2013-11-13" version="1">MPQNTPSLTRRTPISRRRLLAATGSISLGALAGCIGGGTDGTAGDDATDSQDTTWQTTTLTDVLTGRSFSIAELTGPVAIQSFAVWCPKCERQSREMANLNGPVTAVSLNTDPNEDAQQVREHAETNGFDWRFAVAPTEMTDSLIAEFGPAIVSAPSTPMIVACGDGKATFFSGSQQSVTELQSAATECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY67</accession>
    <name>U1MY67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01267</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89115">
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        <property type="gene ID" value="J07HX5_01267"/>
    </dbReference>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="131" mass="15209" checksum="35B07A4C8785AEB6" modified="2013-11-13" version="1">MVGSVPAILREQAKEQIAREPECRRDPQHDDPSRNENEDQLPFVVAARGSRLGQPAEQQARQRERHPRHRVRQRRQPVTDRHDRYVTVTESKTCEFVGRHCLTLVVVELVERPGDDGDRRVRSNIVGHDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY88</accession>
    <name>U1MY88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01133</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88983">
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        <property type="gene ID" value="J07HX5_01133"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="169" mass="18073" checksum="BDF7F2055BDA21B2" modified="2013-11-13" version="1">MQIRDATVTDTKQIRTLHRTAIEQLGGQAYTDTQVTAWARGCSSAQYAPAIEADGVVFLVADRGTDITAFGSVRLSPPEAYHASADAELTGLYVNPSTARSGVGTQVCTELERRAAGQGVETISLSASLNAVPFYTAQGYDRVQTHTHEFSPHVGTGVTGEIVEMRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYC2</accession>
    <name>U1MYC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoadenosine phosphosulfate reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01323</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89170">
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        <property type="gene ID" value="J07HX5_01323"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="47"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="321" mass="36567" checksum="542E9AA5BC881267" modified="2013-11-13" version="1">MSAFPEYVDVEYAAGDNESSADYPSLESKIEQAVEVTRAGLAEYEQPAVMWTGGKDSTLTLYFVTEVAREFGLETPPVVFIDHFQHFDEIHEFVDHWADEWGVELIYARNEDIGAYADEQALAPGDEIPVAALDEHNQHHVREILEYEEETFPFLLDTYVGNHLLKTVALNDALETHDFDGVLSGVRWDEQEARAEETFFSPRHDPDIYPPHDRIHPILQFDERDVWEAFWNYVVPETVPGFPEGHVPTSATDLPGGLEWSDIPVSPKYVAGYRSLGSEVSTEKTTDEPAWLQNLDDTTERAGRAQDKEDLMERLRDLGYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYS1</accession>
    <name>U1MYS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01478</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89320">
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        <property type="gene ID" value="J07HX5_01478"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243747_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043952">
        <property type="entry name" value="DUF5783"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19095">
        <property type="entry name" value="DUF5783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="106" mass="12315" checksum="0F88A5431CD64869" modified="2013-11-13" version="1">MTAFDPEKFDQKFDHYFTELQQAYSRAFQTMHAEYDSGLVHAIDQQVLAESEPVYEGDGHFRIELGDDPASADQLRAEYENLAAVLETYCDELEHELRVEFEFADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYS4</accession>
    <name>U1MYS4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01336</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89183">
        <property type="protein sequence ID" value="ERG89183"/>
        <property type="gene ID" value="J07HX5_01336"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032621_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="351" mass="38597" checksum="279F1CD1E173DD04" modified="2013-11-13" version="1">MTELSXXXXXXXAQRDVDPFLDAAAAGGPHSIVTGRGPSGAMHIGHIVPFYFAKYLQDQLGTLVYIPVSDDKKYVLNNDSLRGISDYTRENVFDLLAVGFDAERTRIIIDTADADVVYPLAAAFGKEVTQSTVDATYGSPENIGLSFYPAVQAAHLLLPQLVAGRHPTLVPIAVDQDPHVRVCRDIAAKQRYDLDKPGALLSKFLPSLDGPGKMSASDDAPSILLSDDRSTVFDKLQTHAYSGGQTSVEAHREHGGDPAVDVSYQFLYYFFEKSDERVEQLAREYRNGTLLSGELKQLAAEKIADFLEAHQQRRADLGSLSSELPQYRLSEDERQNARTRVGYPDDSIAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYV8</accession>
    <name>U1MYV8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="13" type="ORF">J07HX5_01378</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89223">
        <property type="protein sequence ID" value="ERG89223"/>
        <property type="gene ID" value="J07HX5_01378"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009678_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="10">
        <location>
            <begin position="91"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="9">
        <location>
            <begin position="206"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="12">
        <location>
            <begin position="405"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="11">
        <location>
            <begin position="578"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="667"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG89223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="762" mass="85617" checksum="C17BAEED8246C7D7" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB5</accession>
    <name>U1MZB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01531</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89373">
        <property type="protein sequence ID" value="ERG89373"/>
        <property type="gene ID" value="J07HX5_01531"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3263659_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4657" checksum="333F77F979EB0448" modified="2013-11-13" version="1">MKRSTDRQINSRQGKITSNNSFSYLSVKNNERSRLSGPVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZE3</accession>
    <name>U1MZE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01566</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89408">
        <property type="protein sequence ID" value="ERG89408"/>
        <property type="gene ID" value="J07HX5_01566"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="221" mass="23935" checksum="1E15AC0CEF69FA4F" modified="2013-11-13" version="1">MNEESVHPEATALAELVGPDHNPVQRRMAAHASEESFPIVGPTVGAWLLTLTRAIGAERVFEFGSGFGYSASWFLRGMGSDGEIVLTEIDADELALAEQYFATADDTDRVRFEHGDAIEIIETYAGPFDIVLLDNEKPRYREAFKTVEQKLRPGSLVVADNILAGPIDRGDVRALLDGASAPAASDPSRGIATYLRYVRDRPGETVLVPFGEGLSVTQVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZU2</accession>
    <name>U1MZU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01744</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <location>
            <begin position="45"/>
            <end position="95"/>
        </location>
    </feature>
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        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10148" checksum="0DD3C7AC9AE7DC69" modified="2013-11-13" version="1">MASETHTPPGACHWWKYLRCPGVHPEALPYELVVANANNKAFLTPPRTPAPTLSQSRLAHSITGTPRPTTDGKQPATPRHAPGEHATAAVRPGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZX4</accession>
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        </location>
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            <end position="121"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89760.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="16446" checksum="33C0894B4D304DBD" modified="2013-11-13" version="1">MGWLSDRIGRNAAMSVCMAAGVAGYTLFVLGPGFVSIVAATVLVGVAMSWGATMLPKFLDNMSPDEEGMGIGLVRTTYMVFGASGSVGVGLLADQFGWARTFLILAGILGAVLLLIGGSALRRRSLRSLRVSLRHRALRTGTGLTPGWEWLRYIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1N041</accession>
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        </submittedName>
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            <taxon>Archaea</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89683.1"/>
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        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
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        <location>
            <begin position="122"/>
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        <location>
            <begin position="167"/>
            <end position="194"/>
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        <location>
            <begin position="200"/>
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        </location>
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        <location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
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        </location>
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        <location>
            <begin position="511"/>
            <end position="539"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89683.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="566" mass="59659" checksum="919CBB6B41635C0B" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1N069</accession>
    <name>U1N069_9EURY</name>
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        <submittedName>
            <fullName evidence="15">Thiamine-phosphate pyrophosphorylase</fullName>
        </submittedName>
    </protein>
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        <name evidence="15" type="ORF">J07HX5_02017</name>
    </gene>
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        </lineage>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <reaction evidence="1">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
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        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
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        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="14">
        <location>
            <begin position="10"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ERG89845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="44845" checksum="3E90983BB09DC61D" modified="2013-11-13" version="1" fragment="single">MTTPTEFETYLVTQESLAAGRTTSEIVDAALAGDVDAVQVREKDASAAQQLAIARELRGPTADADVALLVNDRLDVALAADADGVHIGDDDLPVAAARAQFPDGIIGRSVSTVEAAQAAEADDADYLGVGAVYATDSKKMAAEKNGIGLETVAAIADSVSIPIVGIGGVTPNRAAAVTAAGADGVAAISAITAADDPEAATRRLSEAVTAGKRRAETPGAVDLDESLTAVTETAPLVTAITNAVTINDVAQTINHLGGLPVMSDDEREVEAMITGADACLLNMGTVSEVGEATMLTAGRAANDTGTPVVVDPVGVGATPTRDMVADRLLSELNVAVVKGNYGEITALAGDDATVRGVESVGEYDDIAETALVCARTYDTVVVASGETDVVATDHAAYKLSAGDPAMGEFVGTGCMLGGAVATVAGVADDPLEAALAGTLAIGVAGEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0C1</accession>
    <name>U1N0C1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial transferase hexapeptide (Three repeats)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02057</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89885">
        <property type="protein sequence ID" value="ERG89885"/>
        <property type="gene ID" value="J07HX5_02057"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_16_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18199" checksum="0AB04C2CA2992D92" modified="2013-11-13" version="1">MSDDRRRRTTQHPTPGPHNSLHRWYAVRSPVRVAVNYLVILVVRVSPSLRLKRWLLRRLGMAIGDNVAWGLESTPDVFWPDLITVEDDAIIGYDATILCHEFLTNEYRTGPVVVREGAMIGAKTVVLPGVEIGANAQVAANSLVAADVPPGKTVAGVPATPVEKNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0D5</accession>
    <name>U1N0D5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01955</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89783">
        <property type="protein sequence ID" value="ERG89783"/>
        <property type="gene ID" value="J07HX5_01955"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090237_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012015">
        <property type="entry name" value="UCP_HTH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004955">
        <property type="entry name" value="HTH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="27890" checksum="120DE2952CC02E89" modified="2013-11-13" version="1">MADDSGDGVRVLQSKRDATRYQILVQIAQRQPAVNQQEIADVIGVTPQAVSDHLSELVETSFVEAGGRGRYQITNEGVDWLINRTDGLQAYLEHVTGEVIEQIGVESALATAPIDEGDQVVMTMHDGYLHADPTRKQGATAVAVTNASAGEDVGITEFDGVVALDPGTVTIGSVPAIRNGGSDATDATTVAAHADEAALVAAAGVEAVATARAAGVTLDLRFGTTDAVSEAATRGLDVFVLVGADQLSTHTDALREHTVAYELVEITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0F4</accession>
    <name>U1N0F4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01975</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89803">
        <property type="protein sequence ID" value="ERG89803"/>
        <property type="gene ID" value="J07HX5_01975"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893103_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6649" checksum="7CB19A8004A93D0F" modified="2013-11-13" version="1">MAQVKSIAALHERRWASHRIRCLLGPAVAAGKLSPMVARWLVVGALPIGAVRYPTALESGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0S8</accession>
    <name>U1N0S8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L15e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_02091</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89918">
        <property type="protein sequence ID" value="ERG89918"/>
        <property type="gene ID" value="J07HX5_02091"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080796_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_L15e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="PTHR11847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="9132" checksum="D3E5FFB9EE719B9F" modified="2013-11-13" version="1">MLNSYWVGEDGSQKWHEIIMIDPNHPAIESDDDLGWICDDVHDSRALTGQTSAGKQNRGLGERGKGTEHTRPSLSSDRNRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3M2</accession>
    <name>U1P3M2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00244</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88102">
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        <property type="gene ID" value="J07HX5_00244"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="162" mass="17628" checksum="608E7882F1C13640" modified="2013-11-13" version="1">MYPRLKSWASPHKGFRPTLHDCHGRVARQRSARRTVLFGRGVLSPGFIRRGVGVWKRTFATATRHGDRLTHTGLIPGVLSNAVTSRTVDPCRSGDGLDPGFGSLPGYSIRGRITSAPVPGPVWTQHSITTRTLEIFESIENQPANGPKRGDPGSIRRASSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3M7</accession>
    <name>U1P3M7_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Glutamate synthase domain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00250</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88107.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88107">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="377" mass="41100" checksum="A3E9A020B924EAEE" modified="2013-11-13" version="1">MTADNGSSTGLGDPSDARANCGVGVVMNLDGTSTHDIVRDGLDLLSCLEHRGTTGADPDTGDGAGVLLQIPHEFFSAVVDAPLPAAGEYAVGSLFLPQDETVRAELIELIEQTLAEEGLETIAWRTVPTGEAGIGETARSSEPVVRQLFVRPADEIDTTAFDRRLYLARRTIQRRARDRGVEREQCYVVSLDRQTVVYKGLLTAGQLPAYYPDLTDARVGSQFALVHARFSTNTLGAWHLAHPYRNIIHNGEFNTIQGNINWMRARENDLEHEAFGDDIDRLTPIIEAPNQSDTASIDNALELLLETGRELPHALRMLIPEAWRAPETGVSGHREAFYDYHASMIEPWDGPALVAATDGDRVGAVLDXXXXXXXAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Q9</accession>
    <name>U1P3Q9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00285</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88142">
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        <property type="gene ID" value="J07HX5_00285"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846234_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="307" mass="34073" checksum="2A9297D8D3742098" modified="2013-11-13" version="1">MRFDRLRLEQFKPFEATEVALEPGVTVINGVNGSGKSSLLEAAFFALYGARTLDGTMDEVVTVGADSSRVELAFTHDNTAGQITRAVRVRDDQARTTRCVLAAGDTTVEGATDVREQVTALLRMDANAFRNCAYVRQGEVNALINASPDERQDILDDLLQLGRLEQYRERASDARVGVGRVRDDVDGALAEVKAQIADKEDANLYAQRDTVREQLDELAADRTRYEDNREQAKTTLEDAEAVLEEQVERREELAELREELTTLRETIEAXXXXXXXAGSGRCSTSASGVRSTGCSRRALKERHRCHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P415</accession>
    <name>U1P415_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00395</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88252">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3300652_0_0_2"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4818" checksum="77BB5D3EE5435C64" modified="2013-11-13" version="1" fragment="single">FETIRTFVVEDLSRFYIQVVRERMWAETDDPEKRAATRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P454</accession>
    <name>U1P454_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease VII, large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00430</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88287">
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        <property type="gene ID" value="J07HX5_00430"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1840492_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuc_VII_L" evidence="1">
        <location>
            <begin position="55"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="139" mass="14786" checksum="96054525AC0C1708" modified="2013-11-13" version="1">MGVGTEAVVEATVDFYSNRGDYQLVIADHWPLGTSDRQAQREQLATTLAVERLWLFNANCEQSVPPFPTRVGVITLSAGSAVEEFCVTVTGRSPQTTVSLHPESVQGEGVVSAVVTSVHALDADPTIEMIVINRGGSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P465</accession>
    <name>U1P465_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00440</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88297">
        <property type="protein sequence ID" value="ERG88297"/>
        <property type="gene ID" value="J07HX5_00440"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54_N" evidence="5">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="4">
        <location>
            <begin position="97"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="237" mass="25721" checksum="0D070B2E90F4F553" modified="2013-11-13" version="1" fragment="single">MVLDNLGSSLRSTLGNLRGQSRISEEDVEEVVREIQRSLIQADVDIGLVRELSGNIETRALEEEPPAGTSPRDWVLRIVYEELVGLVGESTELPLQRQTILLAGLYGSGKTTTAAKMAWWFAKKGLRPAIIQTDTDRPGAYDQAKQMADNAEAEFYGDPTADDPVQIAEAGLAATEDADVRIVDTAGRDGLNEDLIGQIERIATAVDPDRNLLVLDAAMGQSAKDQAREFENAIGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4N5</accession>
    <name>U1P4N5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-oxoacid:acceptor oxidoreductase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00622</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88477">
        <property type="protein sequence ID" value="ERG88477"/>
        <property type="gene ID" value="J07HX5_00622"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017038_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="4">
        <location>
            <begin position="14"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="5">
        <location>
            <begin position="233"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="538" mass="58468" checksum="DE55ADA75E4A251C" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4R0</accession>
    <name>U1P4R0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00653</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88507">
        <property type="protein sequence ID" value="ERG88507"/>
        <property type="gene ID" value="J07HX5_00653"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1550704_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="44"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="173" mass="19128" checksum="72EEFD5C53FCE62F" modified="2013-11-13" version="1" fragment="single">MTEPESYSFRRYLDAKQTVDERARDTRVEETFRSALADHSRLRICEIGAGTGTTAQAVHEWTDVPVEYHAVDVDQSLLDVATARATDTDDRFDITVHAADALDHLAAASEPYDVVIGQAFLDITNVRSAMEAVSASLAAGGVGYFPITFDGVTRFLPSIDTGFDDRIERRFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P541</accession>
    <name>U1P541_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00808</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88662">
        <property type="protein sequence ID" value="ERG88662"/>
        <property type="gene ID" value="J07HX5_00808"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2067717_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12433" checksum="2BB692D4CAB7B699" modified="2013-11-13" version="1">MSTTRAATALAHSFVVTDERSCWGATGAQRRRLEYVMLGHFGAACGSSARGDLSMSGFGPITDTHPGLLEITLEGGSGKDGVGHRRDLPFGCYVGRSRNGSRLLLLPAETYAPAYVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5K7</accession>
    <name>U1P5K7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type Fe3+-hydroxamate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00963</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88817">
        <property type="protein sequence ID" value="ERG88817"/>
        <property type="gene ID" value="J07HX5_00963"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="3">
        <location>
            <begin position="62"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="399" mass="41930" checksum="40F156D36E2B148B" modified="2013-11-13" version="1">MKRVLALLIVLLAVGPAVAGAAAVDDTAVGPAQVNDEQSCEFPVEVEDATGETVVIEEEPTRVVTLQANAAQHMWSIGAKDKVVGMPVQDYTSYLNGSENRTGILAVGDSGFLSPDIEQVIELEPDLVLAPDITGDTAADLREAGTTVYQYPAISNFEQMYGVVEDVGKLVGACEAAPATTASVEETVDTIGQAVEDQQAPDIYYEFSQFTAAPGTIEHDVITRAGGNNIVRESDFDRSYGQLSDELIIQRDPEFLILQEGAPIPDSEAIRQTTAVQEDQIIRINPNFISQHGPRTVEPLQTIAEGLFPETVTQAINNAGSTQMENTTEAGSGSSSESGSDSGANTDEETSESDAEGDDEPADREPTPGADDDSGGSGLTVVAAAAAIAAVTALLARRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5L2</accession>
    <name>U1P5L2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00968</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88822">
        <property type="protein sequence ID" value="ERG88822"/>
        <property type="gene ID" value="J07HX5_00968"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3411375_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="29" mass="3269" checksum="3E527E0B12C02167" modified="2013-11-13" version="1" fragment="single">MTEWSGRRIRLTASRSAGCEGSHPRKKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5S0</accession>
    <name>U1P5S0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="1">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamylcysteine synthetase</fullName>
            <shortName evidence="1">GCS</shortName>
            <shortName evidence="1">Gamma-GCS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gshA</name>
        <name evidence="2" type="ORF">J07HX5_01003</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88857">
        <property type="protein sequence ID" value="ERG88857"/>
        <property type="gene ID" value="J07HX5_01003"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044848_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="364" mass="40627" checksum="5A5061397CA27CC5" modified="2013-11-13" version="1">MDRDGHAGGGAATFRRLGTIGVEEEYFIVDETGRPVAGTDTLVYGPDPPAVLADRLDHELFKCVIETQTPVIERPEAIEPTVKSIRTGLLEHARAQEYDIAAAGLHPAAQWRALDHARKDRYQAQLDRIQYPQHRNTTAGLHIHIGVDDPDKAVWVANEVRWHAALVLALAANSPYWNGFDTGLASARALIFEGLPNTGLPTAFDSYAEFAAFEQRLLESGAIADRGELWYDVRPHTGLGTVELRVPDAQHDPAWVTGLVKYVHALVLDLCARYEDGEPASGRRREILDHNKWRALRHGHDAKLFDRELSTLVDLGELVEREVDRLGVTALRKLYARESGVARQRRVRREGGPDQLCDALRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5T1</accession>
    <name>U1P5T1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01018</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88872">
        <property type="protein sequence ID" value="ERG88872"/>
        <property type="gene ID" value="J07HX5_01018"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2748008_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7682" checksum="6E208FEDA0457262" modified="2013-11-13" version="1">MEAVGRPRRHSLTRGSESLPFQEWEDLKPVNYSIELLILELKQLGVPARGGGPVGLAVFLLDHYLLGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1P614</accession>
    <name>U1P614_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01137</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88987">
        <property type="protein sequence ID" value="ERG88987"/>
        <property type="gene ID" value="J07HX5_01137"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033621_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="85"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="271" mass="28557" checksum="0F74C5073F90F5BD" modified="2013-11-13" version="1" fragment="single">MSDRSDTPDLSRTSRYERITDQTSSGVFAACAAVTILTTLAIFITLLSTAVDFFSVVSLREFVAGTDWSPNPAGGEVIFGIVPLVIGTLTVTITAAFVALPIGTLTAIYLSEYASERTRSVLKPMLEVLAGIPTVVYGYFALVYVTPMLQATVLPQLGTFNALSASLMIGIMTIPMVSSISEDAMSAVPDDLRNAGYGLGATKFEVSTSIVLPAAISGIVSSYILAVSRAIGETMIVVVAMGSQARMPEIKNALFGVPYINPADVLFESGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6C7</accession>
    <name>U1P6C7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Disulfide bond formation protein DsbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01269</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DsbB family. BdbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89117">
        <property type="protein sequence ID" value="ERG89117"/>
        <property type="gene ID" value="J07HX5_01269"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128688_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012187">
        <property type="entry name" value="Disulphide_bond_form_BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43469">
        <property type="entry name" value="PTHR43469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="139" mass="14369" checksum="CE398580CFB05BBC" modified="2013-11-13" version="1">MGHTDQTRLLRATTVVAMAGVVGSVLFESLGYTPCRLCYRQRWLLTAVGVVSVGCLRYRSGALYSLGVVTALTGATVAAYHTGLQLTAASQSGCAAGGCETVSYRIAGLVTIPMLSATAFGLTAALLAAAVYDRMSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6K6</accession>
    <name>U1P6K6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01361</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89207">
        <property type="protein sequence ID" value="ERG89207"/>
        <property type="gene ID" value="J07HX5_01361"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1063976_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="27510" checksum="361B59E908C07D7E" modified="2013-11-13" version="1">MRAVLTRLVVMDSMTAAVSALGLVLLVLVAGVVNGVAGFGFAVVATMGLAVVVDPTTAVTFMIVPMVGVNLALVRELSGTQLRSCGRRFWPLILTALVGTVVGMVALETVPTTPLRVGLGVITLGFVATVQRVLALPGRTRVTEGCFVESPTGMAGVGTISGVLFGGTNVGVQLVAFLRSCDLAHGLFVGVVALVFVGINTVRIGVAAGLGFYPDVAFIAGSAVAVLPAVSGVALGQRLRQRIPERTRRGAVLALLSVIGLRLVLAGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6U3</accession>
    <name>U1P6U3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps9</name>
        <name evidence="8" type="ORF">J07HX5_01450</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89292">
        <property type="protein sequence ID" value="ERG89292"/>
        <property type="gene ID" value="J07HX5_01450"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_A">
        <property type="entry name" value="Ribosomal_S9_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019958">
        <property type="entry name" value="Ribosomal_S9_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03627">
        <property type="entry name" value="uS9_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="14476" checksum="425215F85C974E52" modified="2013-11-13" version="1">MVTNTSGKKKTAIARATVKQGSGKLRVNSRPVELADPETARLKMVEPFRVVDDDLRSEVDIDVTVEGGGIMGQADAVRTAVARGIVQYTNDAELRDAYMAFDRSLLVNDVRQSEAKKFGGPGARARYQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P746</accession>
    <name>U1P746_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00087</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87946">
        <property type="protein sequence ID" value="ERG87946"/>
        <property type="gene ID" value="J07HX5_00087"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="34162" checksum="951C04D6FD816995" modified="2013-11-13" version="1">MSSSYVSGRAFAGIGGLGLLGLAPVALSKYYLGVLTLALIYAIFALSLDLAWGYAGILTFGHAVFFGTGAYIMAVLLPEYPVVGGLTATVVAGAIGVVVAGPLLYRGVEAEYFALITLAFGVIAEQVATSWTDVTGGSNGLLVRADSLSRAGVSVELSTMTVYAVVVGAVIGTYAIVRRVVNSSFGAAVIGIAQNEQKARALGYDVARYRTMLFGVSGAIAGGSGALYTVYSGFVSPSLLGFELSTTALIWVLVGGRGTLTGAVVGAVGITLFENILSGVFVFAWTLILGLTLVAVVVALPGGLVGATTRLRAWLEEPIRWLSRQSARRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1P763</accession>
    <name>U1P763_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01540</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89382">
        <property type="protein sequence ID" value="ERG89382"/>
        <property type="gene ID" value="J07HX5_01540"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="141"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="23905" checksum="C81F471D67E23A02" modified="2013-11-13" version="1">MQPGSQQEIRVLHVDDDSSFTDLTEPFLKREDDRFAVGTAASVSDGLEQVRNNPPDCVVSDYNMPSMDGLEFLRAVREDHPNLPFVLFTGKGSESVASDAIAAGVTDYLQKNKGPEQYELLANRIQNAVNARREAKRAGRQERFTTRILDTLEDVFYVLNKNGSLRRWNSRLPELTGYSEPELAEMQATGLFPTTSTSTLSTLSRRSSQLGRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P799</accession>
    <name>U1P799_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01585</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89427">
        <property type="protein sequence ID" value="ERG89427"/>
        <property type="gene ID" value="J07HX5_01585"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2662225_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043813">
        <property type="entry name" value="DUF5795"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19108">
        <property type="entry name" value="DUF5795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="75" mass="8158" checksum="B2DF2D90E148C28E" modified="2013-11-13" version="1">MADNRVVQGRMVTPKRLAALIEGDEVIDAEPIADADKTCPDCAGNVLAVGYMPSALEFVTGFKCQDCDWHTTDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7F2</accession>
    <name>U1P7F2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01648</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89487">
        <property type="protein sequence ID" value="ERG89487"/>
        <property type="gene ID" value="J07HX5_01648"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020279_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B3_4" evidence="1">
        <location>
            <begin position="96"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="487" mass="53252" checksum="F55CD94E64885241" modified="2013-11-13" version="1">MPVVDLDPNELRQLIGRDRPDDQLRSDLFALGIEFEGWTDDEKMRVEFAPDRLDRLSVEGIARSLRYQYGDAHGVYVPDTNNAEWQIAVESTVPDARPYVTSAIVRGLDLDDAALESLIQLQEKLHATMGRGRAKGAIGIHDLTMLKGAAVGGQKSLRYTGVAPDGDSFVPLDSDAELTPAGVLADHPIGDKYGTLVADYDRYPAIYDDIGLFSFPPVINGRRTKVSTASRNLLIEMTGTDQWTIDRMLNVVCYALSARGXXXXXXXYGFNELDPRYPDLGTVGGRHERSRLEDTVRDSLVGLGFEDMLNFHLIASEENFDRMGLASPDASGSDTLGHTPPVRIREPYSKAYEVLRTWALPSLVMVLENNTHRAYPQYLAEVGLAAGLKDDATTGATERRTVAAVLADVEASYDDARGKLQTLANVFGTTLTTPPTDHPSFIDGRTASVVLDGMPVGVVGELRPAVLVDHDLELPVAAFEFRLDALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7F4</accession>
    <name>U1P7F4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S3Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosomal protein S1e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps3ae</name>
        <name evidence="6" type="ORF">J07HX5_00213</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88071">
        <property type="protein sequence ID" value="ERG88071"/>
        <property type="gene ID" value="J07HX5_00213"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062507_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00359">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030838">
        <property type="entry name" value="30S_S3Ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_S3Ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018281">
        <property type="entry name" value="Ribosomal_S3Ae_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01191">
        <property type="entry name" value="RIBOSOMAL_S3AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="207" mass="23520" checksum="D5FB16B3161EEF4B" modified="2013-11-13" version="1">MSDRSVSRQKQEKNWYDVQAPEQFDRADLGMTPADESEKLLGRTIETTLGDLRDDPSQNNTKLTFRLTEVATDTAYTEFIGHELTRDYMRSLVRRGSSKIEAYITVLTTDRYRVQIQPVALTTKSADESQEQAIRRTMIDRVEAAGEDRSFTDLVDSVVESRLSSAIYNDAKTIYPLRRVEIQKLTLEARPEEVAAEEEASASVTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7L0</accession>
    <name>U1P7L0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00269</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88126">
        <property type="protein sequence ID" value="ERG88126"/>
        <property type="gene ID" value="J07HX5_00269"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="40"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="389" mass="41278" checksum="DF14D375F1482761" modified="2013-11-13" version="1">MTTHHPQQPYSAADRVQRVAPSATMAISNQAAALEADGINVADLSVGEPDFDTPENIKQAAREALAAGETGYTASKGIPELRAAIAERHQADGIDCGPEHVLVTPGGKQALFEVFQAFIDPGDEVVLLDPAWVSYAAMAKLVGASLTRVDTTPHGFALEPALDALASAVSDETELLVVNSPGNPHGAVYTDAALAGVRDLAREHNFTVVADEIYDKITYERSQTSLASMPGMSDRTVTINGFSKAYAMTGWRLGYLIAPEPVVGQAETIHGHSVSCATNFVQHAGVEALQNTDDTVEKMVAAFERRRDLLIEMLADHGLEVPAPAGAFYLMLPVADDDQSWCETAIEQAHVATVPGSAFGTPGYARLSYAAGADRLREAIDRLAANNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7V8</accession>
    <name>U1P7V8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01818</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89647">
        <property type="protein sequence ID" value="ERG89647"/>
        <property type="gene ID" value="J07HX5_01818"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1880984_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="15086" checksum="BBAFA5ABE564F8D1" modified="2013-11-13" version="1">MPEKQANRIVMSHDGDGREPLLTTRNGRPSTTSLRAHINVLTRPCHYTGDCPHNRQQGECEAAQYEYSQRCPSSVSPHPSRRSAITPWLNNGHRKELISDRMEYQPTPSTNTMTLVPNRKGGNFGASNSTCNSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P898</accession>
    <name>U1P898_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA-binding protein, contains TRAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01954</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89782">
        <property type="protein sequence ID" value="ERG89782"/>
        <property type="gene ID" value="J07HX5_01954"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121271_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="15407" checksum="192A64534171EDF3" modified="2013-11-13" version="1">MVEIDNSLKSLFTATVRERDGRFVIELPEREIDHGVVQSGETYRVAVLPSEREAGDGAESETRDKTGTDQRVTEPPAPPVDEGEVREVTVESLGDQGDGIAKVERGYVVIVPGTRPGDTPTVRIEDVRENVAFATIVDETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8B4</accession>
    <name>U1P8B4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01969</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89797">
        <property type="protein sequence ID" value="ERG89797"/>
        <property type="gene ID" value="J07HX5_01969"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949146_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6669" checksum="8A7DCA509F7E0446" modified="2013-11-13" version="1">MLNSEEMDELLTKLTFVILIIDCIVLYLYPNPMTGMFVIALTGGFTILTQLRELITQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8B7</accession>
    <name>U1P8B7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF547 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00500</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88356">
        <property type="protein sequence ID" value="ERG88356"/>
        <property type="gene ID" value="J07HX5_00500"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054137_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="66"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="265" mass="29160" checksum="F10426890AEE1A6C" modified="2013-11-13" version="1">MEHSVDSTVDQSDEPTMGGSQQAVADDNPVTMSRQLLEGVRREQPVTPHQNAIAALDEADLEPVRTDRATALAFWLNVYNASVQLLLEDRPELFESHRQFFGTDAVTVAGIDLSLDGIEHGILRGNRSKYGLGYLPRLTTTGLGAAYRLEVDPRVHFALNCGAASCPAVLAYEPATVDQTLDDATRSHLTQTVNYDETTGHVRVPRLCLWYLGDFSGPSGILSLLEEYGQLPAGASPPRRALRFDSYDWSKAPRKFADESRTELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8E3</accession>
    <name>U1P8E3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00525</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88381.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88381">
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        <property type="gene ID" value="J07HX5_00525"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2909103_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6832" checksum="53545F694058889D" modified="2013-11-13" version="1" fragment="single">MAIKRSDTLNKTGRQFPMGLLAVVSALLGVVTLAYLIDHPFLIDHPYSPLVRRAEIIAVICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8L1</accession>
    <name>U1P8L1_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Phosphate uptake regulator</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_00611</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88466.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cellular phosphate ion homeostasis"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="1">
        <location>
            <begin position="137"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="341" mass="37167" checksum="A32691E172C0C34B" modified="2013-11-13" version="1">MDTRKVQQLGPSTLAMTLPARWAAEHEVEKGDEVSLRYGRGTLTVVPGSVRSTDSEATVDASGLNGNALERAIVSQYVLGRRIINIEAAETLQSDQINAVYEAQTRLMGLGVIEETPTSIAIRCSVDPADFTLDSLLERLESTGSTMRTEAIDAIADATPELAQRALNRERQANKIFMLLLRLIFTAYRNPTLAQAVGLDDGLPLLGYRSIVKNLELIADDAEDIAEVAVAAGEDGLDIDAEAMSRVQSYTNEVDEMSELAVQAAVQRDHDTATAVRERFPEIESRGETILTELPEMDNQSLLRVRAVLVSLGEVAQYAVRNAEVATNLALDEESEHITIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8L9</accession>
    <name>U1P8L9_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_00621</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88476">
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        <property type="gene ID" value="J07HX5_00621"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2872641_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="7011" checksum="23E748098796FCCC" modified="2013-11-13" version="1" fragment="single">MSNLVPYPTDEVAAFLSAVDEAVVVEMNATAQFRGLTQRELGRFGSKLSSMLKYDGEPFEPGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8M2</accession>
    <name>U1P8M2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PGF-CTERM archaeal protein-sorting signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_02049</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
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            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89877">
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        <property type="gene ID" value="J07HX5_02049"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="14485" checksum="9F5E536ECC60882D" modified="2013-11-13" version="1" fragment="single">LVGDEWAGSSNVLSGEDEGVDIIAERVPDDGEFNEFPIDGQDSYVAMIHFVNDDTTAGTEASPGSFPVLPNVNGGEGVAPGGVTTQAQVTAQVDDDGGDTAAGDGDGGDAGDSDGGGPGFGIGGAVAALGGLGYAIRRRLDDDNGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8P8</accession>
    <name>U1P8P8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02080</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89907">
        <property type="protein sequence ID" value="ERG89907"/>
        <property type="gene ID" value="J07HX5_02080"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094841_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Sensor" evidence="2">
        <location>
            <begin position="31"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="23815" checksum="B54767E402E96E67" modified="2013-11-13" version="1">MQVPPRLGPPRSVAGIFGVLFRGQTYRNLLYLAVAFPVAVLYGSILATGFVLGVVLTVVGIGLALLVGVVVLARWVAGFERWLANALLDVELTPADDVGTASTDGPLDNVRDYLNAPSTWRGLGFLSLKFWIGTLGLVLIIFFAQAIQLVVAPLRYPVTIEVGEINGDPVEATITTLPESVLAAVVGSMLCVLLAHVLNAVARVVGHTASALLDGSTTQPRDTVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Q9</accession>
    <name>U1P8Q9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02095</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89922">
        <property type="protein sequence ID" value="ERG89922"/>
        <property type="gene ID" value="J07HX5_02095"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802061_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="6992" checksum="5CF68CB8445A3E92" modified="2013-11-13" version="1">MSCLASEAQSWSSRAYAVSVLAGQGPPIRGQQSLASLDTVVQLTVNSVYCQSMSDQLLLLSVTGATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8V0</accession>
    <name>U1P8V0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00712</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88566">
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        <property type="gene ID" value="J07HX5_00712"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3243432_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="43" mass="4675" checksum="30E2891D128EE0B8" modified="2013-11-13" version="1" fragment="single">MTNTVAYDRFTDAENTGAPLVPEIGCESSTGLEETVFSHRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P981</accession>
    <name>U1P981_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00842</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88696">
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        <property type="gene ID" value="J07HX5_00842"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="182" mass="19855" checksum="C67D54964B5B809C" modified="2013-11-13" version="1">MVNRPRVTFDTTHDEFTVELYADRAPRTVQNFLGLARHDPAADADPAPDTNTWADPDTDEVRGDSLYQGATFHRVIDGFMIQGGDPTGTGRGGPGYQFDDEFHDDLSHDGPGVLSMANSGPDTNGSQFFVTLDAQPHLDGRHAVFGEVVDGMETVEEIGSLPTDGDDRPQEEVRVESVHVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9B2</accession>
    <name>U1P9B2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00872</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88726">
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        <property type="gene ID" value="J07HX5_00872"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="26526" checksum="A34E9806874E6805" modified="2013-11-13" version="1" fragment="single">MKWLYAEGVDAVYVDDLTDVLSTHWCAEVNAKTHQFWTVRAFIDRLSYTAEEYGITVGVGQNPIHPEDVRRVASKTTSTETATCSGVRVVTKLTPTCARLERCLNSRLANPKSGRWLGPRVSTGTTTVGRRYHTFPREQVLTRSAQTEYRRREACLHEWIANIPTGGIPRLQPWENVNIVSALSAVVRVVWRRCGRVLTIVFRVFRRVAAALACASPSVTVSGWLCRDELASPCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9F5</accession>
    <name>U1P9F5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00912</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF19096">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="26184" checksum="118C26C04A0FE222" modified="2013-11-13" version="1" fragment="single">MAGPIRLRHSEESWDDERVDRQLRRPLANTFGATRCDPQHAAPPAYTGCRLEMDNGDLALFAYHDDTGAYWLGNTETPKSLWRTNKKRFEKAPYPVSRWAQRELLSDLETAAPWLTAYDHVAWFFLPVLFSKDGRETTRAFFNNHAAGFPDASRDDGLAFYQRLLSTGVLDDHRYTMASKLGTSQQNDLVRMRATMAEFNAAQLLVEADQTFTPEIELDSGYALDYRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA17</accession>
    <name>U1PA17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01094</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_01094"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
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        <property type="entry name" value="LUMAZINE_BIND"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="95"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="95"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="202" mass="21551" checksum="4FF937499C81F176" modified="2013-11-13" version="1">MFTGIIEETGTVQAATTEADGRRLRIETGLEGLTRGQSISVSGACLTVESHGDGWFEVFLAAETVDRTYLGNAEPGTVVNIERALPADGRLDGHMVQGHVDATATVRTVEQLDEDWVFGFDLPTGVGQYVVEKGSISVDGVSLTVAEKDASKETFTTAIIPETYAVTNLSAKAPGDPVHLEVDVIAKYVESLIEGYTSTTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB10</accession>
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        <submittedName>
            <fullName evidence="4">Cell division GTPase</fullName>
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    </protein>
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        <name evidence="4" type="ORF">J07HX5_01433</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tubulin"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="3">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="13388" checksum="E55981331690F29B" modified="2013-11-13" version="1" fragment="single">MQVGAIGIGQAGGKILDTFLAYNQEIAESPIRSALAVNTAETDLLGLTHIGDDQKLLIGEDTQNGGGVGADNKTGAQVTSQSIERIHEGLEQMPRHELDGFLILTSLGGGTGSGGTPVVTRHINSMYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB94</accession>
    <name>U1PB94_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01504</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89346.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="439" mass="49511" checksum="28239EE2F74A99AD" modified="2013-11-13" version="1">MGLREDFERFREVGEQRRQDLSEFIQYGDLGGSGRDAVRVPIKIVDLPEFAYDQRDMGGVGQGGDGTPQPGDPVGEPEPGDGDEDGDPGEEGAEHEYYEMDPEEFAQELDDELGLDLEPKGKAVVEETEGDFTDISRSGPTSTLDFEQLFKSGLKRKLAMDFDEEYVRAALQIEGWGPARVFEWARSSENLPVSRAWIEKAYSSLPADERVVYADLAAMEAAVDRTGTSERIRREGVDQIPFRRQDERYRFPETVEEREKNVVVVNIRDVSGSMRQKKRELVERTFTPLDWYLQGKYDNAEFVYIAHDADAWEVDRDEFFGIRSGGGTRISSAYELAADRLDAAYPWTEWNRYVFAAGDSENSSNDTEENVVPLMETIDANLHAYVETQPSGNAINATHAEEVERQFRSTDDVAVAYVSSPEDVTEAIYEIMSTEATNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBB0</accession>
    <name>U1PBB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01509</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89351">
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        <property type="gene ID" value="J07HX5_01509"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
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        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
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        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
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        <location>
            <begin position="127"/>
            <end position="165"/>
        </location>
    </feature>
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        <location>
            <begin position="232"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="444" mass="47093" checksum="A98A3EDBB07AC6BE" modified="2013-11-13" version="1">MTVGSTVLAATGLTASGVAGQAVLTVTALSQVAVFSLSLLGVLLIGRAALTYDDLPLKRAGTLIVTGLGVTSLPFWWLLVGTVSTPTILSLTTTQLVATGGALFLGQFGTRLFTDRPLTGHLARETILDTMSESVIIADQNDRILDANEQAAETFGVEQSQLPDRRTTDIGITPAMSDDVVVLDTNSGVREFRVSRTPLSAPRGSPVGYSYRLRDVTDKHTQEQKLEVFNRILRHNLRNDLDAIRGFAEAIRADGGEPGHADRVVDISGELVELTAQLETANKVLTDHTPAAEACDLVAVAEAAAETARARAGAGTDAVTVTVTTTADEPVRVETDPKILRFALAELITNGLKHSTEPAPELELRLEDRPDGASVAVCDDGPGLPANERAVLVAGEETPLRHGRGIGLWTVRWAVKRLGGELAVADRDPTGTTVTVRVPDGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBE0</accession>
    <name>U1PBE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01539</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89381">
        <property type="protein sequence ID" value="ERG89381"/>
        <property type="gene ID" value="J07HX5_01539"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2103406_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="13262" checksum="E0277438B520EC98" modified="2013-11-13" version="1">MATRRLFKLPLDPDSIDDVRAHFDSLEDRHALVERGLALEGMNAETAWLDEREPALYYLHEESKTYPADVDESDIDEELQELSNEHHGFFQQVVAPGHEHPDDLVEFERLFSASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBE2</accession>
    <name>U1PBE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01544</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89386">
        <property type="protein sequence ID" value="ERG89386"/>
        <property type="gene ID" value="J07HX5_01544"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051421_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051741">
        <property type="term" value="F:2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044649">
        <property type="entry name" value="MPBQ/MSBQ_MT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031164">
        <property type="entry name" value="SAM_MPBQ_MSBQ_MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44516">
        <property type="entry name" value="PTHR44516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51734">
        <property type="entry name" value="SAM_MPBQ_MSBQ_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="SAM_MPBQ_MSBQ_MT" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="182" mass="19966" checksum="2B6EC12848BE7DA3" modified="2013-11-13" version="1" fragment="single">VNPLVWTKQMRDEAIRRLEIAPGDRVLDVGCGTGFATTALARRSDEVHAIDQSPHQLARAVEKLGRRGSVRFSQADAERLPFPDNSVDIVWSSGAIEYWPRPVATLCELRRVARPDGQILVVGPDAPDGRFTGWLADAIMLFYDKAEADRLFAAAGFATAEHYTRQARLGGPRAIVTLATPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBG9</accession>
    <name>U1PBG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01574</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89416">
        <property type="protein sequence ID" value="ERG89416"/>
        <property type="gene ID" value="J07HX5_01574"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490325_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9246" checksum="0DC60A8318237AA2" modified="2013-11-13" version="1">MTNSAVSPVQFNCRFRGNCHPVQFKLAPVAPTVGMAQEDIQSGKQGRQCSLTAIRVTRERDGISTDNGATLGWSVVMTRPGLVNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBM3</accession>
    <name>U1PBM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01630</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89471">
        <property type="protein sequence ID" value="ERG89471"/>
        <property type="gene ID" value="J07HX5_01630"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1943782_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="14669" checksum="ECA5CC8F2C0A2B51" modified="2013-11-13" version="1">MLVPNASSSFGARGCCARWSVLGAQLPVDFQQDNTGGGRMVSQWLLNTRRLKRKDVVELTLDRPVSPVGDNGRAYRRISRDPKVFVVRMRSICVQITLRYRLSGRLRLDEHRGERHVCYSSMSDFCPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBN2</accession>
    <name>U1PBN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase of the beta-lactamase superfamily III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01642</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89481">
        <property type="protein sequence ID" value="ERG89481"/>
        <property type="gene ID" value="J07HX5_01642"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085057_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="67"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="317" mass="35144" checksum="B4F8E232C607171A" modified="2013-11-13" version="1">MYQQSPGKSSVVLPGVTNRESQCARVQKMVMKLTVLGSGGNTPTPLPTCDCRVCTEARKRGVPYARRGNAVFIHDEQVLVDAPELVWETLNRAAITEVEYVFLSHYHADHVLGLRALQAVGMEEPPVTTFVSDPPTLVLSQQTYDRAIAGNEVLGMLAEQWADTKILADGETIDLGGLRVKHIAAPIEAGGPNDISGFLFEDSQNGGTAVFISPDENKRFELGRLPELDLWIKECGYFRETPEGDPLVTDVAEETGLANELRFDESLEQVRAVEPDQTVLTELEELYRRSHDDYQRLADQYDELNLTFAHDGLELSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBY0</accession>
    <name>U1PBY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01757</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89591">
        <property type="protein sequence ID" value="ERG89591"/>
        <property type="gene ID" value="J07HX5_01757"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_718668_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="1">
        <location>
            <begin position="38"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="384" mass="40936" checksum="1D0806D8705BC4FF" modified="2013-11-13" version="1" fragment="single">SSIRLLSRPAAYLSATNFVTNFESNPYLPVSYTYFAMTDAYIALEGQRVLEATARAPGQTRGELVFTTAYTGYEESLTDPSYEEQLLTFSYPLIGNYGVRAERFESDSVHPRGVLARELTDDVATWLQDVGVPAVDTLDTRAIVGAVRDEGAMQAGIAAGPGASPEAALAELSQCVPISAYTDIGARVSVNNPIIHNPAGDGPSVALIDCGVKGSIIDALTERDAVVHQLPHDATPGMVEARKPDVLFVSNGPGDPESFTAAAKLVEEYAGDRPLAGICLGQQVVANALGGRTTKMEFGHRGVNQPVQDLRSNRVVMTTQNHGYAVADGGDELTVTQVNVNDGTPEGLDSDTLGIRTRQYHPEANPGPHDSLSFFDEVIELAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC94</accession>
    <name>U1PC94_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01883</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:phosphorylation"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="His_kinase_dom"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
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        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
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        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="326"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="544" mass="59428" checksum="E505D2121DA7546D" modified="2013-11-13" version="1"> </sequence>
</entry>
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    <accession>U1PCF9</accession>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="37"/>
            <end position="165"/>
        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG89781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="213" mass="23222" checksum="0368AA2DA490CEBE" modified="2013-11-13" version="1">MSALGSSGRYRRSLRLGLVKRSSRRQSAPXXXXXXXIASGCDEFHARENSVVGSIGVVGSRLGREELGEKVGLEYRRFVAGEYKDAGSPWRELSDQDTEYIQGQLDDFYDAFVATVAEGRDLDEEFIRATEARVYIGTEAAENGLVDSCGSRETMEDRLADRIGVDNLRTQPFEPQQGLTDRVGSGARSIAYAAGAGVASALVGDEDDPRIRI</sequence>
</entry>
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    <accession>U1PCT0</accession>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="15"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="18164" checksum="A808D9707F6CEDFF" modified="2013-11-13" version="1">MDDDGSGPADKDPPGIRTATGALIIENEETLLVQYRNNGEEWYTPPGGGQQFGETLHEPLQRESRAELGVELRIGSLVAVRHYIADNNDIEGETKTHQLELMFHCSLPDDIQPGEGCRPDENQVAVEWVGFNSLREIYFFPEKLKPLIPEFSHETGAGSGLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCT9</accession>
    <name>U1PCT9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methenyltetrahydromethanopterin cyclohydrolase</fullName>
            <ecNumber evidence="4">3.5.4.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methenyl-H4MPT cyclohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_02074</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58018"/>
            <dbReference type="ChEBI" id="CHEBI:58337"/>
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        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MCH family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89901">
        <property type="protein sequence ID" value="ERG89901"/>
        <property type="gene ID" value="J07HX5_02074"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529174_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018759">
        <property type="term" value="F:methenyltetrahydromethanopterin cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003209">
        <property type="entry name" value="METHMP_CycHdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02289">
        <property type="entry name" value="MCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012765"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00020597"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="17824" checksum="0DB875EAEA5B77C4" modified="2013-11-13" version="1">MLAVETDQLPGDAVAAHVAERAGVAESSVFLPAFAAASLTGSVVAASRASELATMRLTELGYDPQNVLSVTGSAPVPPVADDEAVAMAWANDAVAYGGQVHLVLDEPPTAPAALASTAAAEYGLPFVEIFESVDWAYAELDRALFAPAQVTVDVVGGESYVAGEPDDAALAAAWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PD17</accession>
    <name>U1PD17_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02159</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89986">
        <property type="protein sequence ID" value="ERG89986"/>
        <property type="gene ID" value="J07HX5_02159"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020823_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6124" checksum="DDE3424C405E39B1" modified="2013-11-13" version="1">MCDTGPNIVGIQLPDKMLDQIDAFAVRNGYATLSAVVSDIFQRADTNRHVQYRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFW1</accession>
    <name>U1MFW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00200</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88059">
        <property type="protein sequence ID" value="ERG88059"/>
        <property type="gene ID" value="J07HX5_00200"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="16349" checksum="AE5F9E054CA3AF75" modified="2013-11-13" version="1">MATVSETRIENHERVQPNDTNNYSSAHGGKVVKWMDEVGAMSAMRHAGTTCVTARINQLDFRQPIPQGNICVIEAYAYKTGQSSIRVRITASREAPRTGEREQTTDSYFVYVAVDENNDPKKIGALDVTSSQDRDLRQAALDGETNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFY9</accession>
    <name>U1MFY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolyl oligopeptidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00236</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88094">
        <property type="protein sequence ID" value="ERG88094"/>
        <property type="gene ID" value="J07HX5_00236"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="228"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="439" mass="48539" checksum="45D26D64C6421079" modified="2013-11-13" version="1">MDVYTIDPNGGPATRLTDGDVVASNLAWSPDGSRITFASWPADNWYRPREIHVVDRDGSTPVSTGLDGTASQWGPPVWLDTETILAGVANKGWVRPYAFDASADAPTPRFEAFGRDRSVRLIDVGGDQIVCSVDDPDDGHELYALARADLDAPFDEAATRLTAFNEELLEAPATFHRLKSTHDDAEGDGEPVTVESMVYTPPGFEPVSSEPRPTILWPHGGPMSYDDPEFSFTTNYFTSRGYIVLKPNYRGSSSYGRAFCETLRGRWGSVEIVDQLAALDDLVERGWADPDRLFATGFSYGGISTAFLVTETNRFAAAAPEHGIYDRRSSFGTGDSQVWNTNELGVPWENPERYAANSSITAVDQIETPLLITAGEDDWRCPPTQAEQLYVSVRKQGIDAKLVLYQNEHHNVGDPDRAIHRVETLEAWFERHDPITDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFZ8</accession>
    <name>U1MFZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenocysteine lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00247</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88104">
        <property type="protein sequence ID" value="ERG88104"/>
        <property type="gene ID" value="J07HX5_00247"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="18"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="368" mass="39019" checksum="F5745776CDF2C895" modified="2013-11-13" version="1">MTLLALRKEIPALNTGGYLNYGAHGPSPRRVVAAVTETLEQHEYAAAEADPYEAAFASYDRSREQIAALLNVDSDCIALTESTTDGIARVATALGLEAGDTVVRTDLEHPAGMLPWRRLERDGITVRVVETERGRIDRDAFADAVADATVVCFSAITWTHGTRLPVADLVGIARDAGTFTLVDAVQVPGQTACDMSEWEADVIAGAGHKWLLGPWGAGFLYVNPASAHKLAPTMIGYRGATATDEGVAYDPGARRLELGSMSPGPHAGLAAAIDAIRTVGLSTIEGRIEMLTNRLKAGIDEDRLLSPRAYHSGLVTIDAQDPAATVDRLAEAGLVVRSVPTPDAVRVSVHAVTTEDTIDRVIEAFATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG28</accession>
    <name>U1MG28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00287</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88144">
        <property type="protein sequence ID" value="ERG88144"/>
        <property type="gene ID" value="J07HX5_00287"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1745486_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="16043" checksum="7946D229126561C9" modified="2013-11-13" version="1">MPERFCTTGNQINIMTEPDVEGDDSIGGSTGSISVHDPTEAISVRDPVEELHDPTERFEQTRPDEQASSDAAEAAVKSAFWRLVLALDLGLAAFPLGTMLIWFRGDWSLGGPLVAAGVVVLGYAGYRYTTLRRRLNADESDVGVDEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG49</accession>
    <name>U1MG49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00317</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88174">
        <property type="protein sequence ID" value="ERG88174"/>
        <property type="gene ID" value="J07HX5_00317"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2678740_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="8290" checksum="ED27467A06453F41" modified="2013-11-13" version="1">MVLLVFRLESKNTDGQTLCRRYEDGSREPEFVTTETEIAVGFSDPQTASQRQELLLVNPEALASAGPLLVYECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG95</accession>
    <name>U1MG95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00372</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88229">
        <property type="protein sequence ID" value="ERG88229"/>
        <property type="gene ID" value="J07HX5_00372"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_948659_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="3"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="293" mass="30606" checksum="63889148B859742E" modified="2013-11-13" version="1">MTGLSTRKRSGRATSGQLIVSVSAFSVLFGVFATSRVGGRPVGRGEAESDGRPSIRDXXXXXXXFAEQVRVPAADYNLVTLPSEISPRDAAVLGCRYMTAYHALANRAGLGGGEWLAVHGCGGVGLSAVQVGAALGARVIAVDPDQAARERARTVGASHALDPEAGDPVETVTETTDGGADVSMDALGIATTCQNSVNCLRTRGTHVQLGLTTDAERGRVALPTDRMTRWELSFVGARGMPPTQYDALFDLISATKIDPGALVGRELPLTAVSDRLAAMTDYQTTGVEVVTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGV6</accession>
    <name>U1MGV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00614</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88469">
        <property type="protein sequence ID" value="ERG88469"/>
        <property type="gene ID" value="J07HX5_00614"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1323989_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="21768" checksum="1A5756A8A8E98821" modified="2013-11-13" version="1" fragment="single">AGAAMTTAITDREAIAHWLNCEGQTAAGLSRNERVQALLAEKPGAAGFLWRDQPVEWYHTRIGPQSFRQLRPICGPARLQWRQLSVDGTITGIATRLHAGTAPTAGSGVSYAAIRRYRDRLAAGERLAPLVVRTKRGATPWHVVDGNHRAVALAWHALETGQYSPQTGYVAVTGRSVIAAVADHLRAVVQRVRGRRVAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGW9</accession>
    <name>U1MGW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00634</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88489">
        <property type="protein sequence ID" value="ERG88489"/>
        <property type="gene ID" value="J07HX5_00634"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544150_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="173" mass="19060" checksum="18AC91100326FC4E" modified="2013-11-13" version="1">MRRRKLLTAGAASVGVFAGCPDPFDHDHETYSPEQYSFAGVAVIAHGSSVDYQPYEVTAEVRSADESISKKSANVHDEKNPHMLALTISGGLSPHSKHTICLDANSEATEAEGSREVATDELSIRDTKQRFLNKTVAFCFLIFDLSSFSYKPRVVTDDWPESGVDLHPRGFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH38</accession>
    <name>U1MH38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00740</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88594">
        <property type="protein sequence ID" value="ERG88594"/>
        <property type="gene ID" value="J07HX5_00740"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2565585_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010545">
        <property type="entry name" value="SPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06550">
        <property type="entry name" value="SPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="7822" checksum="70494D05A992FE68" modified="2013-11-13" version="1">MLAVSAGEFLDAPVVLSVLNANLPAVGAVLGGFLGMAALLVLLHRVEGAHAGLPPLNAGVLLGYLVGAVAAGVPVTTALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH78</accession>
    <name>U1MH78_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphatase</fullName>
            <ecNumber evidence="1">3.1.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00800</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.3.11" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88654">
        <property type="protein sequence ID" value="ERG88654"/>
        <property type="gene ID" value="J07HX5_00800"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2067716_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12883" checksum="A820AE3C0CE435E6" modified="2013-11-13" version="1">MSVTDHDQLNESMLLSGYDPDGEFLRQFYQQTRGVRRVGSVALNLAFVAAGNADGAWEFNTSPWDVAAGLRILKEAGGVATNGENTPYAFELDTAGTRNPLLVSNGSLHEQLVRRLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHW7</accession>
    <name>U1MHW7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="1">1.8.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01065</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.8.4.11" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88919">
        <property type="protein sequence ID" value="ERG88919"/>
        <property type="gene ID" value="J07HX5_01065"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_6_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="3">
        <location>
            <begin position="24"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="207" mass="22894" checksum="EBB5A7365463BF0C" modified="2013-11-13" version="1">MMALTPQTIREYDRTAPAETETATATFGLGCFWGPEAAFAALSGVVRTAVGYAGGTTSDPTYHDLTDHTEVVRLAYNPATISYHDLLEHVFKTYSHRSQPAKRQYHRVVLAETDRQADAAETAVAEITAGHETVATRLERLETFYVGESYHQKHGLRGKRWVTEVFDEAGYDDDAFRRSPAAAKLHAHVTGHTVDVPFLNARSRDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHZ5</accession>
    <name>U1MHZ5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01107</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88959">
        <property type="protein sequence ID" value="ERG88959"/>
        <property type="gene ID" value="J07HX5_01107"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079807_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046260">
        <property type="entry name" value="DUF6293"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19810">
        <property type="entry name" value="DUF6293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6293" evidence="2">
        <location>
            <begin position="3"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="314" mass="35267" checksum="66580B6777F792FE" modified="2013-11-13" version="1">MQTHIVPVGFDYDRLIAPLVRDQFDVDAVVLLEGQVGSEANVEYSRQLAQKLERDFESLLGAETEWLSIEDVYDYDTAFEQAFRLINAELDAGKEVWVNVSAMPRTVSFAFATAAHSLMVEREGDRDRIHTYYTVPEKYLETELAEQLRHTRELLAAALADEATDEQLRTGLTNTEQLLEEFDERGTTVGAKQFDGEHVLELPVASFSNVKPFEELILFTLGDHGEVGSVSELANTIAAELGQECTDAFRSKVIYAVDQLGPGGKGYVERDQRGNSYRTRLSRIGRLWVRAHADESETRTRVERETPGTNGRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIH6</accession>
    <name>U1MIH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01358</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89204">
        <property type="protein sequence ID" value="ERG89204"/>
        <property type="gene ID" value="J07HX5_01358"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="45"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="21329" checksum="CC5BF2907B18D0F2" modified="2013-11-13" version="1">MDRQAVRTAWDEVSETYARNRDPNGSDADLIDELLDRLGPAPRVLDAGCGDGARTLANLTDTSVGIDISREGLELAAETLPNGGLVEADMVSVPVAGDAVDAVTAYHSVFHVPREEQPAVYEEFARITQPGGWLLMTLPGGRYETVRRGWMGGRMLFSTPGREQTLRQLDAAGYGEIETTTATDPLGSSTEFVFAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIU1</accession>
    <name>U1MIU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Ser protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01502</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89344">
        <property type="protein sequence ID" value="ERG89344"/>
        <property type="gene ID" value="J07HX5_01502"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028588_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="27"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="690" mass="79805" checksum="42FB990423E1752C" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ90</accession>
    <name>U1MJ90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01694</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89529">
        <property type="protein sequence ID" value="ERG89529"/>
        <property type="gene ID" value="J07HX5_01694"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140786_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="36"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="15387" checksum="409779165B8FDF49" modified="2013-11-13" version="1">MAEADHSSARDDEATTNDRFDDLVVDEGPTLDNALTCVFDIHHHEVRTYNALLDRPASTVAELSAELDRDRSNVNRSLATLREKGLARRERRLLDGGGHVYQYSATPLSETRELLHDTLEAWATTAHEEIETFDPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJM2</accession>
    <name>U1MJM2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01861</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89689">
        <property type="protein sequence ID" value="ERG89689"/>
        <property type="gene ID" value="J07HX5_01861"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="240"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="576" mass="59427" checksum="F5FAAF1363CA85FD" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV30</accession>
    <name>U1MV30_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cetZ</name>
        <name evidence="7" type="ORF">J07HX5_00071</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ERG87930"/>
        <property type="gene ID" value="J07HX5_00071"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058152_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="2"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="357" mass="37179" checksum="0DF21714415E21BF" modified="2013-11-13" version="1">MKVTLIGVGQAGGKVTDAVAKFDRQREFGAVQETLAVNTAQTDLCALDTDTMLIGRDHVNGHGVGGDNELGAEIMQAESAEVLERLGGKLSAQTEAVVIIAGLGGGTGSGGAPALAAELRAIYTVPVYVLGILPGRNEGQLYQANAGRSLKTVTREATATILIDNDAWRQTNTSLETGFATINNRIARRVGLLFAAGEATDGVGESVVDSSEIIKTLANDGLASLGYANAPASADPAENIDTITSLARRAMLTGMSLPDAVAAEAALFVVAGQPPRIARQGVEKAHSWIEEETGSLQVRGGDFPTDSDQLGALVLLSGVERSDRVQAFLDRSRGAHDETASTDSCDQFASEKLDNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV32</accession>
    <name>U1MV32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00076</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87935">
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        <property type="gene ID" value="J07HX5_00076"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ArsR-like_HTH"/>
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        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
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        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="159" mass="17417" checksum="4427B02DF78F2901" modified="2013-11-13" version="1">MTENIDDVDEAILHALQEDARSRSSKEIAERTGTADSTVRKRIQQLETDGVIKDYSVDIDYQASGYPLRMLLFCTASIPERGDRIPEILAIDGVVSVQELVTGEENLLVTAVGESDGDITPVAQELLELGLTVADEVLVRSHERTPFGGFEGTPRTSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVF4</accession>
    <name>U1MVF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00232</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88090">
        <property type="protein sequence ID" value="ERG88090"/>
        <property type="gene ID" value="J07HX5_00232"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1032913_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="148"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="29378" checksum="07D3863025ED37EA" modified="2013-11-13" version="1">MPVRRQPSRQCETTVTLAANDTTAVVSYFRYAFERVILAVLSVYAVVTVLFFAATGTAWFEIRERLAVAGFNNADQAATSALRDRLIAERGLDRPLYSRYADWLVDVATLQGGESLVYRASVVSVLDGRVQTTLGYVIPGIVLGVVLGVGLGVFVALRRDGVLDWTARLGAYAMLGVPSFMLVLYARFFDSLTLGAGDLDTWVVSSLVVASAVLAGQLRFARTAALEQTGRAFVTALRAKGASRIHLLRHVLRTPRYRCCRCRSASCCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVF9</accession>
    <name>U1MVF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00237</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88095">
        <property type="protein sequence ID" value="ERG88095"/>
        <property type="gene ID" value="J07HX5_00237"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1168544_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="61"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="231" mass="26367" checksum="9EFBB2273C03A142" modified="2013-11-13" version="1">MTTEPETQEDTSGATDRRFAATIDWEQHWDRTDREQLTEMRAAGERMAERLDRYVQSFPETLLDVGCGPAFTLFELAANHPKSEFLGIDPAGSVLAQNRRLAADRGLRNLRFRQGSLPTVGLDRQFDCVTCIATLHYVAAIEQAIERLFETTTPGGTLVFNYPNRHTRRLYKADPETDPERFELLLSGENVLTRSAIRQHTGRQPRNFWRAVDEPDWRSMGQTNPCVVIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVK1</accession>
    <name>U1MVK1_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00283</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88140">
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        <property type="gene ID" value="J07HX5_00283"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149308_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="11245" checksum="45237770F3E2E613" modified="2013-11-13" version="1">MITCALCRRAFPAGAISDPQAFQRHHLLPERRDTSPTVTLCRPCHDQIHAVFTNDELREKYNTVSALAAADRLDGYLGWIRGTAKLSIDVATSTHVRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVP6</accession>
    <name>U1MVP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00184</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88043">
        <property type="protein sequence ID" value="ERG88043"/>
        <property type="gene ID" value="J07HX5_00184"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068640_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039967">
        <property type="entry name" value="MJ1020-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40517">
        <property type="entry name" value="PTHR40517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="73"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="222" mass="24820" checksum="292F21183359863A" modified="2013-11-13" version="1">MSDQSLPDSPDRDSATYAYEPDATHAFPDDRLNEILAYVENDTEITTYLSAQNVNPVDRMRYNDHGTKHIEIVRNRALRLYELLKRDGVTFNGATDQGLDEADEPVIIALAGILHDIGHVVHRHRHPYYSVPLAADVLDRILPEFYGPAEAVRLKGEVLHAIICHHTDEQPLTTEAGVVRISDGLDMERGRSRVPYELGGRGINTVXXXXXXXHTLESASPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVQ5</accession>
    <name>U1MVQ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00194</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88053">
        <property type="protein sequence ID" value="ERG88053"/>
        <property type="gene ID" value="J07HX5_00194"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2678771_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="7769" checksum="984AF132F28E50ED" modified="2013-11-13" version="1">MSETQRDDPDQVEELSEIFVSVTGDESVTESQDTEGDDRELRDESQIDEAVADGLNDALDGAGPDGGDPGKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVQ7</accession>
    <name>U1MVQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00343</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88200">
        <property type="protein sequence ID" value="ERG88200"/>
        <property type="gene ID" value="J07HX5_00343"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3147842_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="48" mass="5018" checksum="1E8F770696900CA2" modified="2013-11-13" version="1">MDADPQNTSRAYPIVTFAVVDLLLGAAAAGYRLSHPTIAEGVHPPLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVQ9</accession>
    <name>U1MVQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00199</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88058">
        <property type="protein sequence ID" value="ERG88058"/>
        <property type="gene ID" value="J07HX5_00199"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_8_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="27"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="4">
        <location>
            <begin position="466"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="598" mass="64923" checksum="B5C72A32EC3EE891" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVT1</accession>
    <name>U1MVT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00368</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88225">
        <property type="protein sequence ID" value="ERG88225"/>
        <property type="gene ID" value="J07HX5_00368"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042266_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="95"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="29416" checksum="89211087D12A8FF2" modified="2013-11-13" version="1">MSTAWLRTQLLGVLGLFVLLNAAYVLALVWGLGVLLPTTVGFIFTAEPAVLSDLIRLPVSVLTALVLVVGFLAAQIYHGYRRVLAGSKAGDTDATHWITRTVQKLAMTADVPAPAVRVVESDKPSCYTIGRITDATVVVTTELIAVLDANELEAVLAHELAHIANRDVTLMTVTTLFLEVTDRVCHATRLARRAVTNPSALSNRERLLCRFSFPLAALVYLLVLPVLWLFPRLTGRTIKTLSHTREFAADTAAARXXXXXXXGHSYPPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW4</accession>
    <name>U1MVW4_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Phosphoglycerate dehydrogenase related dehydrogenase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_00261</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88118.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016616">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="63"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="31273" checksum="9C54AE946B4CBEAB" modified="2013-11-13" version="1">MWTGSRPSNLHKPVVTTSERLWRSLIRGHELGVCSQADGRVSDRSVTALLSTTLCFTDTVEALVTANFSPSGIDRLESLGFDVEFDPIESRAGRLPVGVLKARLSGVDVFISGFEGVPAELMDAATHLRLIVCPRGGPAASVDISAATDRSIPVLYAPGRNAETVADHTMGLLLAATRNIARAHHRLRMGKDTGDPRADAAAGGERADVTWGIGSESPYTTLRGPELGGRTLGIVGFSQISRRVAKRATMGSAWTSSLTTRLSTTSRWSRSAPRKRPLSGSSVPGATWSVSTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWD1</accession>
    <name>U1MWD1_9EURY</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="2">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7178" checksum="518B2A6CA617E935" modified="2013-11-13" version="1">MPDFRTALGLVSKKAGDTAARQTERQRPAADLASDPLQEHKQTSACCSQLLVDDPADLVAELVRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWF8</accession>
    <name>U1MWF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00600</name>
    </gene>
    <organism evidence="1">
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88455">
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        <property type="gene ID" value="J07HX5_00600"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9212" checksum="E7F306D0776E8C8F" modified="2013-11-13" version="1">MVGGRRSFDRDTANGSAKRILIIADSLFKNMPATEELRCTSDSCELDMFENHYTYEVDEDLAVSDLNCPLCGGTNCLEQITLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWH7</accession>
    <name>U1MWH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00477</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88333">
        <property type="protein sequence ID" value="ERG88333"/>
        <property type="gene ID" value="J07HX5_00477"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968314_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="6037" checksum="0192A1F30FF7D27A" modified="2013-11-13" version="1">MVVLVRKRPVALAAVVDCKKESYRGIASSSSANERGGVEVGAGILGISVLRLKTIVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWU7</accession>
    <name>U1MWU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00593</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88448">
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        <property type="gene ID" value="J07HX5_00593"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156336_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10360" checksum="880F61D365490776" modified="2013-11-13" version="1" fragment="single">RGVLGLGLEDHEAYQRGEMSIFTFRIGPTTVIHVHPSSNAVAPAGQAFDYVALVFDQPIEREGTPRGAGGTARAVYVRDPFGYLVELKEAVSVVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWU8</accession>
    <name>U1MWU8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type transport system involved in Fe-S cluster assembly, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00771</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88625">
        <property type="protein sequence ID" value="ERG88625"/>
        <property type="gene ID" value="J07HX5_00771"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="303" mass="32864" checksum="42F7B67701EE4C6B" modified="2013-11-13" version="1">MATLSITDLHAEVAAESGETILQGVDLTVESDEIHALMGPNGSGKSTLAKVIAGHPEYAVTGGSVTLTLDGGEFEAAEESEWELLELEPNERAALGIFLGFQYPVEIEGVTMVNFLRTALNAKLEEREELFEDDADADEEETADVTNEDAAGYDTAPMEGEAQGEIGVAEFQQILQEKMEVLDMDESFASRYLNVGFSGGEKKQNEVLQAAILEPEMAVLDEIDSGLDIDRLKDVADGINALRDEQGAGVLQITHYQRVLDYVEPDHVHVMLDGEIAKSGGAELAEQLEDEGYEFVREEAHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWZ0</accession>
    <name>U1MWZ0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="10" type="ORF">J07HX5_00811</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the protein translocation apparatus. Forms a complex with SecF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88665">
        <property type="protein sequence ID" value="ERG88665"/>
        <property type="gene ID" value="J07HX5_00811"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007894_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_A">
        <property type="entry name" value="SecD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024912">
        <property type="entry name" value="SecD_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="535" mass="56716" checksum="BACE1E3A39DFE722" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX39</accession>
    <name>U1MX39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00694</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88548">
        <property type="protein sequence ID" value="ERG88548"/>
        <property type="gene ID" value="J07HX5_00694"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070751_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="187" mass="20170" checksum="B2095079EDCF5108" modified="2013-11-13" version="1">MTLVVNAAVALGVAQLPPVLERDYDVPLDPALTLWITAAVFLHALGVVGLPGSEQSFYSTVWWWDHLTHALSSSVVAAVGYTAVRALDTHSPRIHFPDRFVFVFILLFVIAFGVLWEVLEFTLSEAAAVIGNGSVLTQYGLDDTLLDLVFNTIGAIIVATWGAAHLNDVSTHIVERLNGDGDSDTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX43</accession>
    <name>U1MX43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00699</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88553">
        <property type="protein sequence ID" value="ERG88553"/>
        <property type="gene ID" value="J07HX5_00699"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080075_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="22901" checksum="CB30B5A085BA94A0" modified="2013-11-13" version="1" fragment="single">MSDTGQSGAGRREVAYRVLAAEYEAANYSYSAGDEERAPNYVVTPTGARINRLFLVGVLTETEEVSEGVLRARISDPTDTFVLYAGQYQPDEQAMLEATEPPAFLAVTGKARTFQPDDTDQVFTSVRPESINKVDAETRDRWTVQAAEQTLGRIGHLATALSVGAAGPELRAALADHGIDSGLADGIARALEQYNTSTAYLDALRKTAVDAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX52</accession>
    <name>U1MX52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00871</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88725">
        <property type="protein sequence ID" value="ERG88725"/>
        <property type="gene ID" value="J07HX5_00871"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3036627_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6390" checksum="26F4F7352F5C27FB" modified="2013-11-13" version="1" fragment="single">MLKKDDTDSTTGRRTVLGVDLGVNQLAVASTRRLWSTNEFNHWKRECEKRRGDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX82</accession>
    <name>U1MX82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00744</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88598">
        <property type="protein sequence ID" value="ERG88598"/>
        <property type="gene ID" value="J07HX5_00744"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_884264_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="226"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="314" mass="34156" checksum="A57FE4402620BB9E" modified="2013-11-13" version="1" fragment="single">LSWGLRPDDTTPMLFPFFHTGGWNVLTIPLFQLGGTVVITREVEPGRVLELIDHRGATLLVAVPAVLRFICNHDRWEAADLSSLRLVKSGGGPCRETVIDTWTDRGIKISQGYGLTECGPNNFAMPEPFPGKKTNTIGKPGLHLDARVVGEDGTELPPGKIGELELAGPAAGDRYWRNEAETGEAFDDGWVATGDLARVDEDGYFSIEGRKKNMFVSGGENVYPPEVEDVITDHPDIDEAVVVPIPDENWGQVGKAVVEGDPKLSVEQLRSEMDGTLARYKLPKALAVVDEIPTSGVAKIDRTAVAERFGAERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX99</accession>
    <name>U1MX99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate synthase/pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00916</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88770">
        <property type="protein sequence ID" value="ERG88770"/>
        <property type="gene ID" value="J07HX5_00916"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_6_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEP-utilizers_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="32612" checksum="4BB2ECB295258059" modified="2013-11-13" version="1">MTATRVKVNVSIPEAAERAAATGADGVGLLRIEHMILSLGKTPQQYIADHGADAYVDEIVDGIRRVADEFYPRAVRARTLDAPTDEFRQLEGGDDEPVEHNPMLGYRGIRRSLDRPELFGHELAAFRRLYEMGYDNLELMLPLVNDAEDVTRARRLIEEAGIDTDRRSWGVMIETPASALQVETMAQAGIDFASFGTNDLTQYTLAVDRNNEAVADRYDALHPAVLELIGQTIETCRAHGVDTSICGQAGSRTEMVEYLIENGVTSISANIDAVRDVQHEVKRTEQRLLLDSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXB5</accession>
    <name>U1MXB5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00931</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88785">
        <property type="protein sequence ID" value="ERG88785"/>
        <property type="gene ID" value="J07HX5_00931"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447550_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9085" checksum="4F06324B7665E5CC" modified="2013-11-13" version="1">MPILVVVLALLLLSTSRLRGINGLCTGAPEEQYFSAIGPPVSTRDSQTPFGSTDAALNANGVPVPPVEVSTRPGVGVHSKSQQVSGGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXD7</accession>
    <name>U1MXD7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TATA-box-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Box A-binding protein</fullName>
            <shortName evidence="6">BAP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">TATA sequence-binding protein</fullName>
            <shortName evidence="6">TBP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">TATA-box factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tbp</name>
        <name evidence="8" type="ORF">J07HX5_00804</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88658">
        <property type="protein sequence ID" value="ERG88658"/>
        <property type="gene ID" value="J07HX5_00804"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060161_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04518">
        <property type="entry name" value="TBP_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033711">
        <property type="entry name" value="TBP_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="1" evidence="6">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="185" mass="20136" checksum="0B187A5B358F9227" modified="2013-11-13" version="1">MEPKETINIENVVASTGIGQELDLQSVAMDLEGADYDPEQFPGLVYRTQEPKSAALIFRSGKIVCTGAKSTDDVHQSLRIVFERLRELNIRVEDEPTIIVQNIVTSADLGRTLNLNAIAIGLGLENIEYEPEQFPGLVYRLDEPDVVALLFGSGKLVITGGKEPDDASAAVDKIVARLDDLGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXE7</accession>
    <name>U1MXE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00814</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88668">
        <property type="protein sequence ID" value="ERG88668"/>
        <property type="gene ID" value="J07HX5_00814"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167318_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002753">
        <property type="entry name" value="UPF0058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036519">
        <property type="entry name" value="UPF0058_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42203">
        <property type="entry name" value="PTHR42203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01893">
        <property type="entry name" value="UPF0058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140371">
        <property type="entry name" value="SSF140371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10670" checksum="C6B349B86234DBEE" modified="2013-11-13" version="1">MHKDELLELHEQMVLIMKYFSSLERVDDELFEQYDEIDVTPDDVHMSKSEHKHAVFVLGNALATAMSEDEFSDAGRVGKRMQELAEDAERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXE8</accession>
    <name>U1MXE8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00966</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88820">
        <property type="protein sequence ID" value="ERG88820"/>
        <property type="gene ID" value="J07HX5_00966"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2820651_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7071" checksum="27A3DBA253D7BB5B" modified="2013-11-13" version="1">MSNQTEHSEQTDPSTPPEAEAVSTPDSEPTPTPPPEADDQLPGETVLESSQSELNLDGNINRVLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXH0</accession>
    <name>U1MXH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00844</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88698">
        <property type="protein sequence ID" value="ERG88698"/>
        <property type="gene ID" value="J07HX5_00844"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3245212_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="4687" checksum="5A51ED3C0D8FE471" modified="2013-11-13" version="1">MESSAAVKKDDYEPASDDHNSGEPTGVSHTYWSHMHCVYCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXI4</accession>
    <name>U1MXI4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00996</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88850">
        <property type="protein sequence ID" value="ERG88850"/>
        <property type="gene ID" value="J07HX5_00996"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_7_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="3">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="4">
        <location>
            <begin position="141"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="40828" checksum="0B8F0F253B82E063" modified="2013-11-13" version="1" fragment="single">MELFGTAGIRGPVSEIDPSLALSVGQVIGADADEVVIARDGRETGAALAAAVEAGVASGGATPVRAGQLPTPALAFASGGRYGVMLTASHNPPADNGIKLFRDGHELDQSAEQRVERRVEAPPTASWDGWGRPRQSRWLSEYRTAVVEYARDHGDPADGLRVAVDCGNGVASLATPQVLERLGANVDALNANLDGQFPGRASKPTAESLTDLRAYVADGETTLGIGLDGDADRLVIIDETGTVVHEDTVLAILAEHYTRRSTAGEPVVVTTPNASGRIDERVTAAGGRVERVGLGALHEGIARVRSRSGSETSVVFAAEPWKHIHPAHGGWIDGVASAAVLVRLAAATGVATLRAPVAEPPYRKESVACPDGQKSAAMERLEERLPAAYDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXM2</accession>
    <name>U1MXM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01026</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88880">
        <property type="protein sequence ID" value="ERG88880"/>
        <property type="gene ID" value="J07HX5_01026"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127458_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="5">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11785" checksum="B21EDEF411CA9E0A" modified="2013-11-13" version="1">MNLIDYKTRERGIEVKMPNERGTSSSCSVCGHEDEDSRVKRGLWKCDRYDVVAHGDINGADNTKHKTLSVTPPLGDSDNGCLARPRVIQFSRTRGLQPRATAERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXT8</accession>
    <name>U1MXT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00969</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88823">
        <property type="protein sequence ID" value="ERG88823"/>
        <property type="gene ID" value="J07HX5_00969"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893100_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="7364" checksum="A909AF272692D4E6" modified="2013-11-13" version="1">MATSLRGPSKRFFNRIARPPELPFRRSERQIPRLEFVTGKRITHDRVERAENTTDRLTERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY55</accession>
    <name>U1MY55_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <shortName evidence="1">MTA/SAH deaminase</shortName>
            <ecNumber evidence="1">3.5.4.28</ecNumber>
            <ecNumber evidence="1">3.5.4.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtaD</name>
        <name evidence="3" type="ORF">J07HX5_01096</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20716"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57985"/>
            <dbReference type="EC" id="3.5.4.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine</text>
            <dbReference type="Rhea" id="RHEA:25025"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:48595"/>
            <dbReference type="EC" id="3.5.4.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="1"/>
    <dbReference type="EC" id="3.5.4.31" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88948">
        <property type="protein sequence ID" value="ERG88948"/>
        <property type="gene ID" value="J07HX5_01096"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090614">
        <property type="term" value="F:5'-methylthioadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01281">
        <property type="entry name" value="MTA_SAH_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023512">
        <property type="entry name" value="Deaminase_MtaD/DadD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="51"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="446" mass="47093" checksum="06726125720BA663" modified="2013-11-13" version="1">MATLRIANGKVLRPNHTLEHADVLIDQETGTLREIGDVSGGDTVIDATDGIVMPGLVNAHTHVAMTLMRGFAEDQPLEQWLNETVWPVEAALEPADVRAGAQLGVAEMIRSGVTAFSDMYFEVPEIAAVVEQSGLRATLGHTAISVGKDSAAAHADMNRSIETARELAGAADGRIQTTVQPHNPATVDTDVLETHVPAARDADAALHYHTNETEAEVSRVTDETGRRPVVYADDLGMLQPGDTLAHCVHVNDREIELLADRGVTAVHNPAANMKIASGIAPVTELRAAGVAVALGTDGPASNNDLDMFDEMCDAAMVAKIATRDAAALPAEAVIEMATVEGAQALGIDSGRIATGANADVIIVDTSEPKFDPGHNPVTDLVYTASGSDVRHTICDGRLLMHDRQLLSLDLEQTKRQAARQAERLFERAGIADTGAADGPETDLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY74</accession>
    <name>U1MY74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01118</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88968">
        <property type="protein sequence ID" value="ERG88968"/>
        <property type="gene ID" value="J07HX5_01118"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2313685_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10827" checksum="A84AE104105E0E4B" modified="2013-11-13" version="1">MTTLSWLHDETTRVDVESGSATTTVQVAAKPTIVERVRGRLERLDTPPSTPTCAGLPVAIRTVRERPPQQQVGNVLRRLPDPRAVRPPATASTTPWLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYA1</accession>
    <name>U1MYA1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cetZ</name>
        <name evidence="8" type="ORF">J07HX5_01303</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CetZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89150">
        <property type="protein sequence ID" value="ERG89150"/>
        <property type="gene ID" value="J07HX5_01303"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058152_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="2"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="390" mass="41558" checksum="0F0712FD719C6093" modified="2013-11-13" version="1">MKLAMIGFGQAGGKIVDKFIEYDEQTGSGVVRSAVAVNTAKADLLGLERIPQANRVLIGQARVKGHGVGADNELGAEIAEEDIDEIQGAIDSIPVHEVDAFLIVAGLGGGTGSGGSPVLAKHLKRIYTEPVYGLGILPGGDEGGIYTLNAARSFQTFVREVDNLLVFDNDAWRKTGESIESGYEQINDEIVRRFGVLFGAGEVSTGEDVAESVVDSSEVINTLAGGGVSTVGYDAESVDLGNSGGLLSRFKSSEDEKIASANTTNRITSLVRKAALGRLTMPCEIEGTERALLVVSGPSKYLNRKGIERGRQWLEEQTGSMEVRGGDYPISEPNVAAAILLAGVHNVPRIKELQQVAIEAQENIDDIQQESEDNLDTLVEDDEDELDPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYP5</accession>
    <name>U1MYP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01306</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89153">
        <property type="protein sequence ID" value="ERG89153"/>
        <property type="gene ID" value="J07HX5_01306"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143264_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="154" mass="16269" checksum="71F57BB8F48CEABE" modified="2013-11-13" version="1">MTATPDRYETEVRADTIYVGTPDGILPVGSLDVAVTVVGGPSWRIAYSEAFVDSHSDIDTSDAGLTVDVVDMINAMTHSERFVRTLAAQPVSAAVSESLHPDNKAGLSLTPTETEPEAKPNQPPQAGPPADDIVSPRLGLFIGKLLENLETGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYP6</accession>
    <name>U1MYP6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enolase</fullName>
            <ecNumber evidence="7">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">eno</name>
        <name evidence="13" type="ORF">J07HX5_01453</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell surface</location>
        </subcellularLocation>
        <text evidence="7">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89295">
        <property type="protein sequence ID" value="ERG89295"/>
        <property type="gene ID" value="J07HX5_01453"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_0_1_2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="129"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="352"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="7">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG89295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="398" mass="40798" checksum="A042C51F35F87177" modified="2013-11-13" version="1">MTLITDVSLRRVLDSRGNPTVEADVRTDAGGSGRAQAPSGASTGEHEAVELPANTAIAAARERAVPRLIETVYAGDQRAVDKALRAADGTDDFSEIGANSAVAISMAAAKAGADVLGAPLFQHLGGTFRGETPTPLGNVLGGGAHAASGPAIQELLAVPAGAPSAEQAAFANAAVHDTVGDLLADRGYTPGLGDEGAWAPAVDDRTALKIVAAAVDRVTDDVGFEVGLGVDIAATELYDADTNQYRYPDEARTPDEQTAYVTDLIETHDLQYVEDPFAEEAFGAFAALTDQVGETLVCGDDLFVTDTARIERGVAAGAANSVLIKPNQVGTLSGAVDATERAAASGYTPVVSHRSGETTDATIAHLAVATGAPYIKTGAIGGERTAKLNELIRIEHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYR4</accession>
    <name>U1MYR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01326</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89173">
        <property type="protein sequence ID" value="ERG89173"/>
        <property type="gene ID" value="J07HX5_01326"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040997_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="162"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="295"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="388"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="416" mass="47740" checksum="09AA557272B178FC" modified="2013-11-13" version="1">MDLLDASASLWNELNYERRQQFFNGESVWDTTDYRKQYVDITGSATAQQLIRKNTSAWQSFFSLQEEWQNGELDKRPSPPGYWGNEDDGRELRTIIRNDSYTLETGNRSRIEIPVGSQLKDEYDHTGRLRLELCGVPKWDGKQGRLEIQYDKIEDTFRAFQPVTVPDSQQDSPLASHEAALDVGANNLVACTTTTGQQYLYQGRDLFSRFRETTEEIARLKSALPEGRYSSQRIRRLYRKRTQRRDHAQDTLVRNLIEQLYDEGVATVYVGDLTDVLSTHWHPEVNEKTHQFWAFRSFIDRLSDTAEEYGITVRVKSEADTTRTCPVCGEQEGTERNGDLFRCPCGHEAHADLCASRTFLEQQAGKSEVGSMARPVRLKWDDHIWSEIPHSPERVSPNEERTNRSTSIGKVASVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYR9</accession>
    <name>U1MYR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01331</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89178">
        <property type="protein sequence ID" value="ERG89178"/>
        <property type="gene ID" value="J07HX5_01331"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1451372_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="186" mass="19767" checksum="2098A8328C6B934E" modified="2013-11-13" version="1">MIDAATGTLVWERLDGYTNLAENRGGPTIFNGHIVNSGAEATVLSVPGGSTQWRTGITAYDSITGTSQALYIAGDAGGTATIRSFGTGGSINWTVEFGEYDGLGVRYDDIYEFFNLPPAVTDGSILISVRPEXXXXXXXTIGDKSTKTDVVISNSVTPGGHTRISNQLDAKKKADTRSHFTAYRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYZ8</accession>
    <name>U1MYZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerol uptake facilitator related permease (Major Intrinsic protein family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01425</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="U1MYZ8"/>
    <dbReference type="EnsemblBacteria" id="ERG89268">
        <property type="protein sequence ID" value="ERG89268"/>
        <property type="gene ID" value="J07HX5_01425"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="27156" checksum="80D2627E870A24E9" modified="2013-11-13" version="1">MPETYTLRHKAVAEFLGTFSIVFFGAGAVAIDLLTAPVGAGAGVVFVNNGLGLGTLGWVGIALAFLGAVAIPIALLGRVSGQHINPAVTIALLITGRIGLRSSLVYIVAQLAGGIGAGIVFVGIRGEDAVNIGVMGATAPFPGVSAFQAVLAEGVITFFLMLTIMAFAVDDRTPDNAAGPAIGLMVAIGILTTGNVSGASFNPARTIGPYVTNTLFGGPNLWEDVWIYLLGPIVGAVAGAAVYTWVVLDPVEPATPAAGESAAEEAKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ83</accession>
    <name>U1MZ83_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Methionine aminopeptidase</fullName>
            <shortName evidence="3">MAP</shortName>
            <shortName evidence="3">MetAP</shortName>
            <ecNumber evidence="3 4">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">map</name>
        <name evidence="6" type="ORF">J07HX5_01670</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="3 4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="3 4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3 4">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="3 4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89505">
        <property type="protein sequence ID" value="ERG89505"/>
        <property type="gene ID" value="J07HX5_01670"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_7_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01975">
        <property type="entry name" value="MetAP_2_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028595">
        <property type="entry name" value="MetAP_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="5">
        <location>
            <begin position="13"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="32260" checksum="24F9942C8589E3F7" modified="2013-11-13" version="1">MSQVDLQSERYDRHREAGEILTQVRAEAVDRIEVGASHRELVEHVESRIYELGGEPAFPMNVCIDEEAAHATPTADDESTFGEELINIDIGVHVDGWVADSAATVDLSGNDELVAATDAALEAAIETVGPGVDTGLVGDVIGRTIEGYGYSPVVNLTGHGLEEYEQHAAPTIPNRKLPEGVELSVGDVIAIEPFATDGRGKVSEGSDEEIFALEHEGSVRDRSARQALGQITEQFQTLPFATRWLEVDRPAMALRRLKQRDIVHGYPVLKERPGTLVSQKEHSVIITEDGCEVFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ85</accession>
    <name>U1MZ85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01506</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89348">
        <property type="protein sequence ID" value="ERG89348"/>
        <property type="gene ID" value="J07HX5_01506"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1248255_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="221" mass="24172" checksum="AE02DE575E458DBA" modified="2013-11-13" version="1">MRLSETVCPSPVPEPYLASQPTRRAGSPSAVTVGVERTRVGEEDTGGLPALTRRRPSRQSAQRQTGIPGSTHRGSPATPRGRVSGRDTLLLRRCRRRSPLRTVPGRRTRLCPHSHAGGTRCRGLSFAAQTPRPGGKTPPTAGPGTRPGQPARRHPTPTRTRLNSGSSSDSNIASGRCGQTVPVRVRPATPRAWCRSRRLLRRDARRPPSRAHARRTQRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZF4</accession>
    <name>U1MZF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthase/N-acetylneuraminate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01756</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89590">
        <property type="protein sequence ID" value="ERG89590"/>
        <property type="gene ID" value="J07HX5_01756"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_7_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="30089" checksum="292DB2C0610BDB65" modified="2013-11-13" version="1">MDMPIQGVGPPLVTPFETNGDINHDALRELVNRLEAAGVDFLVPCGSTSEAELMTASERRSVIETVAAAATVPVLAGTGQPGLRETTQATAAAATAGADAALVVTPFYYTHSQATFRSYYRDLADRASIPVYLYSVPAYTDVALTAATVGALAEHSNIVGIKDSAGDLGRLVRTVEQTTDAAFDVLVGSASVFTQALAIGAVGGVMALANLAPTALATIADTQPTDPEHARRQNAELVALNRAITSEYGPSGLKWAMRQRGLPAGTPRSPHTALSSDGQATIGSLLDRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZJ0</accession>
    <name>U1MZJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01622</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89463">
        <property type="protein sequence ID" value="ERG89463"/>
        <property type="gene ID" value="J07HX5_01622"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_11_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="264"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="478" mass="52131" checksum="AC193B5BA5E6D6B2" modified="2013-11-13" version="1" fragment="single">MADATSRRDRLVELTNNLDTTLSAWLILGILLFLPQAGSAGTFVTGLIADFVGLLPTADTSGSLLAAVTDAFESAQQQSRSLPTLLSRDVVPNAGYWNGEEWVGTFLGLSPAAAWGIRVGLVYLYSLAWVGWAVFGYWYYRREVRVANWTPRDDVVDRFRSHRWGLFGATIVFFFVVMAIFAPTLGPTTVEQNMRNSYGFEISYWNGQAQTVEQILVGDANLDSQSRGDESRIMPMSYDEYGRFHPFGTMPNGQDLFTFIVAGSRISLVIGLLSVGISAFLAVTLALTAAYYKGRVDLGTVLISDGVMAMPQLLLLIMLTTVLADSWVGDIYSGGFVLAVIFAFTGWAYMWRSIRGPALQVSGRTWIDAARSFGQRPRTIMRKHMLPYILGYVLVYGSMTLGGAIIAISGLSFLGLGIAPPTPEWGRAVNLGQDYITTGSWHISLIPGVLITLVVTGFNALGDGIRDAIDPQSDTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZQ6</accession>
    <name>U1MZQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01704</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89538">
        <property type="protein sequence ID" value="ERG89538"/>
        <property type="gene ID" value="J07HX5_01704"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2856972_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="7334" checksum="6325170D3613FD8A" modified="2013-11-13" version="1">MFAIAWIARVVLLASILSRVNCSYIRNRSDTYRAWIQQLSSVVFTLFGLNHSQKGCESPRSSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZT2</accession>
    <name>U1MZT2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">J07HX5_01734</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89568">
        <property type="protein sequence ID" value="ERG89568"/>
        <property type="gene ID" value="J07HX5_01734"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_5_3_2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="29"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13376" checksum="22DC53AA8DBF7122" modified="2013-11-13" version="1">MDIDTPEIAFDGGLVPVVTQDADSGTVVMLAYASKAALNRTRETGLAHYYSRSRDALWQKGETSGHVQHVEEIRVDCDGDALLYRVRQDGGACHTGFGSCFYRSVDGEVVGERVFDPDDVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0A7</accession>
    <name>U1N0A7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02037</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89865">
        <property type="protein sequence ID" value="ERG89865"/>
        <property type="gene ID" value="J07HX5_02037"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2433731_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031033">
        <property type="entry name" value="Halocin_C8_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04449">
        <property type="entry name" value="halocin_C8_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9038" checksum="5931342299AF158F" modified="2013-11-13" version="1">MNTCSGCYYASKPVCRTVCGAFGGFICGLLGTSLVGAVGCVTFVKAVCWVAEKASGCGDDLAATICKSSGIGVCGPNEDGDIIDADIPYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0E0</accession>
    <name>U1N0E0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobyrinic acid a,c-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01960</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89788">
        <property type="protein sequence ID" value="ERG89788"/>
        <property type="gene ID" value="J07HX5_01960"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022752_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase_3" evidence="3">
        <location>
            <begin position="236"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="437" mass="45103" checksum="BE53DE9A93583403" modified="2013-11-13" version="1">MNGIVLGGTASGVGKTVTTLAVLRALEAAGRSVQPAKAGPDFIDPSHHAAVVDTDQPARTLDPWLEGESGLRRNYHRGTGDICVVEGMMGLYDGDQTSTAQIAELLGLPVVLVVDGSASAASVAATAHGFDRYADRAGRAIDVAGVIAARTHGGAHERAVREALPTGLTYCGRVPPLDGLDVPERHLGLHGGSEAPVDETALETAAAAIRADRLIALAAAPPAPPADHPAPGTGTTVAVARDDAFRFIYPAVRERLAQRATVHTFAPAAGDDLPAGDLDLVYLPGGYPERHAAALAASPGLATLAARASDGLPVLAECGGLMALAETLTVTDSHDMAGVLPCAVTLQDQCQAVDHVALRGQRTSLIAAPGDRVRGHEFHYSAATVGRDAQFAFVVERGQGIDGDHDGMTEYKTLGTYSHFHAESGVFDAALETITDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0F1</accession>
    <name>U1N0F1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02093</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89920">
        <property type="protein sequence ID" value="ERG89920"/>
        <property type="gene ID" value="J07HX5_02093"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="231" mass="24367" checksum="DC09DB8915F88330" modified="2013-11-13" version="1">MEITDKIAVVTGASSGIGEATARVLGRAGATVVLVARREDRLSVIADELNTDTLVVPVDVTDWSAVQAMVETVRERLGAIDILVNNAGVARGGPVGEAEITEMRQSIRVNLEGAMNVAHAVLPVLRESGGGDIVAVSSLSARFPQAGGSAYTASKFGVNGFHRSLRKELSDDPVRVTVVMPGAVITELNDWEHWDGRAMDPADIAETIAFAVSRPAHVELTSISVDTTDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0I1</accession>
    <name>U1N0I1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02000</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89828">
        <property type="protein sequence ID" value="ERG89828"/>
        <property type="gene ID" value="J07HX5_02000"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1192596_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="232" mass="25745" checksum="C7E120B33BFA51DD" modified="2013-11-13" version="1">MGSFEVAVFTTSDLYWDCSSEFGDGYEARDIAAEFIEGAFSRSTNHTVTVLKPDTRVSAPQEQINDSFKSQPPCSGPIDTWEDLRDWWDYWVNDAACKDPHTEAADCNLLLTGASGGGLGGPREACAGGAFTIANNYDSYQNWDDQPAFNQVDTVLEELGHTLVSDMSNEDDGTIPHDSGRLYEHNGTYAITPIGITGDTDYNNCNEYVNKSRWDENAWEARYSPCTEEHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0Q4</accession>
    <name>U1N0Q4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02065</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="J07HX5_02065"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105299_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="16787" checksum="4CDCADDEC6E4A751" modified="2013-11-13" version="1">MEIDSPTPEEAPAVVELWLSLVLDQQRHGAHLVGEANRGPASEMLRQAIADRRVLIARAETPVGFVSFRIEAGAYEQDVTRGLIENVYVVPDRRAEGIGTALLDRAEQALTDRGASVIALEALAANDRVRSLYRKLGYEPHRVEFERQVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0X3</accession>
    <name>U1N0X3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02141</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89968">
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        <property type="gene ID" value="J07HX5_02141"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_881367_0_0_2"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="50"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="241"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="315" mass="33857" checksum="9D6F48023EE08B60" modified="2013-11-13" version="1" fragment="single">DGGKQAKVDPSAVEAATATVRAVVENVERVIVGQHETTEQLVTALLGGGHVLLEDIPGVGKTMLARAVADSFDGKFRRVQFTPDLLPSDVTGVNVYDQQSQSFEFQSGPVFANVVLGDEINRAPPKTQSALLEAMEEQQVTVDGETRTLPEPFTVIATQNTVEGDRAYDLPMAQVDRFMKKLQLGYPGDGNEVEMLDRVVGTHPIDQLEPVASLDDLRAARVATAQVTVSDALKQYATRLATYTRSHAQLGVSPRGTIALVQAAQARAILEGRPYAVPNDIQTEAPAVLAHRIRTGANQDATALVAETLERVPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P341</accession>
    <name>U1P341_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00033</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87892">
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        <property type="gene ID" value="J07HX5_00033"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="94" mass="9889" checksum="95F12D4E06952BB7" modified="2013-11-13" version="1">MILTGELGFGESKSVGFDLSAGFESVTGAASVSFSTSKSSTGVEVSAYSGNDDEEVSYDFPIKRGEHCGVEVHRASVPASEDRKQLLVDGLLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3C4</accession>
    <name>U1P3C4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00138</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87997">
        <property type="protein sequence ID" value="ERG87997"/>
        <property type="gene ID" value="J07HX5_00138"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="33013" checksum="C70E9601A4C04910" modified="2013-11-13" version="1">MSKVDNLIECTECVPPAEAFALIADETRILILEALSNLETPARFSEIRTAVGMADSAQFSYHLRKLTDQFVRKTDAGYELRTAGERIVQAILAGSFTEHPSREIAIDDPCVICGNSLSAQYNDEMLQIECPACGHGHGRYSFPPGGLHGRTDSEVLDAFDQRVRHLHCLAKDGVCPKCNGQVQTLVEENEDCCLGASLQANHVCQQCGCELCSTVGLGLLDQSAVIKFYADHDIRVSETPYWQFRWCVDDHTVERSPDDLSRLSVDITAAQERLRVVVDDDLSIIRTERFTTETSKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P482</accession>
    <name>U1P482_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="4">6.3.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_00456</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88312">
        <property type="protein sequence ID" value="ERG88312"/>
        <property type="gene ID" value="J07HX5_00456"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675302_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="71"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="407" mass="43021" checksum="411B282BCBF704A8" modified="2013-11-13" version="1" fragment="single">VRVANAVQTLTETDPAAVVEYAETVGATLAIVGPEAPLGAGVVDALASAGIYAFGPRQAEARIETDKAFQRRFMSANNIPGCPTFSVFETAAAACEHIDAAGQDLAIKPAGLTGGKGVRVTGEQVDQAAAKEHARTVLQEHDRLVIEQRLTGEEVTVQAFVANGEVRPMPAVQDHKRAFEGDEGPNTGGMGSYADTTPALPFMTDEEYATAVAILKAVVAAMPEYRGVLYGQFILTATGPRVVEFNARFGDPEAMNVLSIMQTDLLSVLTAARDGEPLPTLEFAPTATVCKYAVPAGYPSDPTPGARVNIDERTVQSAHSGELTGVDDPTPTASLFYASVDQREDGIYATTSRSFAVVGQASSIADAETAATAALAEVGDEFRVRTDIGTNASVQRRTERMRRLREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4W7</accession>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CitG"/>
    </dbReference>
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    </dbReference>
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            <dbReference type="EMBL" id="ERG88572.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="75" mass="8027" checksum="5A8EDD66E0AF328C" modified="2013-11-13" version="1">MFLDELAGTTDTLVVTQHGQETAREVRRRARAVRAGSEDADALADEFVDRGINPGTTADILAAALFIALERGVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5F3</accession>
    <name>U1P5F3_9EURY</name>
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        <submittedName>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <begin position="81"/>
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        </location>
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    </feature>
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            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG88767.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5X9</accession>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <location>
            <position position="521"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="ERG88947.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="521" mass="55800" checksum="066D7488731A68B0" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="10041" checksum="C858D6B42FDB1D73" modified="2013-11-13" version="1">MAVTQLDLKQAVKMESLRVEDLYPPNMFKKEDDVYAYEKEDLGITESASYENFDVNDGAMCEPKIIAEDVFTLHLESGSTVSVQNKITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6T8</accession>
    <name>U1P6T8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate (FAA) hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01444</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89287">
        <property type="protein sequence ID" value="ERG89287"/>
        <property type="gene ID" value="J07HX5_01444"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078481_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="118"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="31289" checksum="E5AAAB5D9EF394E7" modified="2013-11-13" version="1">MQYFSLDAEHPATLLARDDDGTTVDLTAAGGFNSFRALAQAAADDGRSIDDLARNALGSSPDAVVDAGVDIDPPSAAGRPVIPDEVWAAGVTYQISEQAREAETGMPALYLDVYDADRPELFFKATPERTVGPGDDVGVRDDSAWDVPEPELAVVLCEGAIVGYTVGNDLSSRAVEGENALYLPQAKIYDRSCAIGPCVVSPETVTDPHDLTISMTIKRAGETVYEGTTSTAEMVRSCEELVSWYTRHNHVPELSVLLTGTSLVPPDSFTLHPGDHIRIDIEAIGTLENGVVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Z5</accession>
    <name>U1P6Z5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00017</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87876">
        <property type="protein sequence ID" value="ERG87876"/>
        <property type="gene ID" value="J07HX5_00017"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1631581_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="162" mass="18037" checksum="B31D96F3B617B10F" modified="2013-11-13" version="1">MTXXXXXXXNWQIEKDFKNRVDDDRWRRWQVAEVPMRQPDQHSTAVGGFAEGAFAAGDSGDAAAIKKFIAKFVEPTSMGRYCEAAGLLPTRQSVFDNSDLYSPDAFPYQQQFRQFLQHGQAPPQFPVYSAVSAAFEDAIRAVATGQTTASDATDRLIQQFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P728</accession>
    <name>U1P728_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00062</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA damage repair.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nre family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87921">
        <property type="protein sequence ID" value="ERG87921"/>
        <property type="gene ID" value="J07HX5_00062"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039703_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02096">
        <property type="entry name" value="Nre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033167">
        <property type="entry name" value="Nre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006979">
        <property type="entry name" value="Nre_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006978">
        <property type="entry name" value="Nre_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38136">
        <property type="entry name" value="PTHR38136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04895">
        <property type="entry name" value="Nre_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04894">
        <property type="entry name" value="Nre_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nre_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Nre_C" evidence="3">
        <location>
            <begin position="312"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="424" mass="45927" checksum="1A48C36DDB81D292" modified="2013-11-13" version="1">MRLDEFIEGFERDESATRRRLAREKSYAIADHLEAVEQQFAETVQGESLVGATAPEIFVGQAGHPRVSAGVLAPVADTAETTDPAAFATDGAWYEHGLGISDVLQRRTSLLNATQSTQVEAADAWAGFRGVQREVAIADHPVDVEVDLDGPPEFDLAVSEVATPTGPQARAIDATLTENPHVSAPVKKTLADDDWAAEGAMTYLYRRGFDVYEINTILSAGALGRERERRLVPTRWSITAVDDVLGQYQRGQLQTAPAVDTVTVWHNSYLGNDYWVVLAPGDWEFELVELKAPGSVWNPAPDGEYHLAADSEGATGRSGYVEETAGAYHAARLAVLEALADRGRQASCLVLRHARDGYWAPVGVWQMREAVRHAFTGDPGPATAETFHDAVETLVGELPVSLAALRRKSTLVAGLQSRLGEFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P742</accession>
    <name>U1P742_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01520</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89362">
        <property type="protein sequence ID" value="ERG89362"/>
        <property type="gene ID" value="J07HX5_01520"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802058_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7106" checksum="C840952024194091" modified="2013-11-13" version="1">MLGLTGSSAAPRTLCKASPTTAETTAATFTLADFVVVAIERSTYWAEEADTVPIEINPYDPIEILSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P757</accession>
    <name>U1P757_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01535</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89377">
        <property type="protein sequence ID" value="ERG89377"/>
        <property type="gene ID" value="J07HX5_01535"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2597561_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8339" checksum="0550724E25D9CBD4" modified="2013-11-13" version="1">MGDRASSSRRQYLAAVTAVATTLAGCSGLQDGSDDAEPSQPNTSDESTGQPDTNASATDDTIHNPPTNRSKRRLRAHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7G9</accession>
    <name>U1P7G9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetrahydrodipicolinate N-succinyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00228</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88086">
        <property type="protein sequence ID" value="ERG88086"/>
        <property type="gene ID" value="J07HX5_00228"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050859_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="307" mass="33075" checksum="57D3EFF166FE676C" modified="2013-11-13" version="1">MSLESEITALWDRHETGTPDAEREPEDELAVLDAFLDALERDEIRAAERIDGAWQSNAWVKRGILLNFTLRSITTHEHGGVTYNDVLSLADTTTLGDHGARNTPNGTVIRRGASVGADTIVMSPSFVNIGARVGDGALVDSCTTVGSCAQIGADVKLGANTLIGGVLEPVEDAPVVVDDGVSLGAGCRVTSGFVIGRDCVVGENTLLTPRIPVYDLVEETVQYGRLPPERRAFARYVESSVSSHELFDGGAYKPAVVATALERXXXXXXXPRRRGRTTTAVARRRLGPEQQDWADQGLSHGFRSRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Q4</accession>
    <name>U1P7Q4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="5">FGAR amidotransferase II</shortName>
            <shortName evidence="5">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purL</name>
        <name evidence="9" type="ORF">J07HX5_00314</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88171">
        <property type="protein sequence ID" value="ERG88171"/>
        <property type="gene ID" value="J07HX5_00314"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061323_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01736">
        <property type="entry name" value="FGAM_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_linker" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="60"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="186"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="79"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="298"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="381" mass="40419" checksum="C7BA2EE75DC42C33" modified="2013-11-13" version="1">MALVEDDRRRIVDRLGREPTRTETALFENLWSEHCAYRTSRPLLAAFDSQGDDVVVGPGDDAAVVALNNEWCLTIGVESHNHPSYVDPYDGAATGVGGIVRDTLSMGAYPIALADCLYFGEFAHEESQYLFEGVVDGISEYANAIGVPTVTGSLSFHPGYTGNPLVNVACVGLLPADRLVTAAADRPGDRLVLVGNATGRDGIGGASFASEDLSEDAETEDRPAVQVGDPYVEKLLIEANEELLDRGLITAARDLGAAGLGGATAEMVAKGGCGCTIDLENVHQRESGMNGTELLLAESQERMCYAVAPEDLSTVKSVAEQYELGCSVMELSPSSXXXXXXXLRVVVSTSAAFAAGSSRSIAARTGLRWRPCRRTLPQCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P824</accession>
    <name>U1P824_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00439</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88296">
        <property type="protein sequence ID" value="ERG88296"/>
        <property type="gene ID" value="J07HX5_00439"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_870156_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="319" mass="34063" checksum="297C4F5D93E4261B" modified="2013-11-13" version="1" fragment="single">YAVEGACGTGKTLIGLLGSIHAMQIGSITLDGETTTLPAFERTVAVTPVKQQLKQFIAEVRRVNRKLPASAPYDPVDAIVLRGMSDVLVYTNADGFDFDAEVTRAFARADADVLEAGSPSQRDQISQLRATTRQLIKAGSPIELDWAVTTPEVCAVEDCRHLVGAPQMAMCPFHMEASPDQDPPWADIVRAERVVELVEALPGDRLQVDGTTTPYPDRFPVIEDVVAYATETGAAHAQAPFDPFYAKASAGLGSVGFDDGAHRVLDRDALVTAAAADGSCPHVCMGTLARNGCGCDWQLQSSVRPTDTAANRGQSRPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P849</accession>
    <name>U1P849_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00460</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88316">
        <property type="protein sequence ID" value="ERG88316"/>
        <property type="gene ID" value="J07HX5_00460"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114819_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014518">
        <property type="entry name" value="UCP022079"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09920">
        <property type="entry name" value="DUF2150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022079">
        <property type="entry name" value="UCP022079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="20122" checksum="C0F717810452B74E" modified="2013-11-13" version="1">MPSDTAIPPAXXXXXXXXESARLLLNLQDDTAIAVAKVLTDYAATAEGTVDEDDDSYLGEEPALAELSGMRETVLAEVELADEDTEMLLEGVQTALMCVLYTAEEYVVSGAPGNGTVPEYVDAAAEAEQSEEIDDALGYCVQAGTLIIDGADLEPDLVEDLEFGLVAEWVNGLDSLQTALEDPDVIEDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8A9</accession>
    <name>U1P8A9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial regulatory protein, arsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01964</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89792">
        <property type="protein sequence ID" value="ERG89792"/>
        <property type="gene ID" value="J07HX5_01964"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153620_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="94" mass="10604" checksum="C9AC22D0AE9EDC07" modified="2013-11-13" version="1">MEDVLWYLLASSRGGNSRALILDALADQPENANQLADELGLDYTTVRHHLDILVENNVLRRAGDGYGDIYLYTDQATHNRKTIEEIIETVTTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P977</accession>
    <name>U1P977_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA replication factor Dna2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00837</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88691">
        <property type="protein sequence ID" value="ERG88691"/>
        <property type="gene ID" value="J07HX5_00837"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2019910_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="10896" checksum="B94CFA5FD72188E6" modified="2013-11-13" version="1">MHAWGAVTGVDGQQTAITQHAESDLAEVTLRPVDGHGDGATPTLTLWGDWVETAAVLAPAMELAAYGVTRDDYQGQRGYATTADARVIVEPSFIIDVTKIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9A2</accession>
    <name>U1P9A2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="4">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pcm</name>
        <name evidence="5" type="ORF">J07HX5_00862</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 4">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88716">
        <property type="protein sequence ID" value="ERG88716"/>
        <property type="gene ID" value="J07HX5_00862"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="205" mass="22226" checksum="F0C899A73D31DE41" modified="2013-11-13" version="1">MRDRRERIVNQIEDRTALGDRVTAALQTVPRHAFVPPDRRTSAHDDRPLPIGAGQTISAPHMMAMMTDALDTAAGTTVLEIGTGCGYHAAVTAELVGASTMYSVEYHAALADRARKTLAATGYDAVMTRVGDGRNGWPAHVPYDRVYLTCAAEAFPPALVEQVRPGGILLGPIGRRRQQLVRAQVRADGTLDRTELGAVRFVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAD3</accession>
    <name>U1PAD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01213</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89061">
        <property type="protein sequence ID" value="ERG89061"/>
        <property type="gene ID" value="J07HX5_01213"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055621_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="318" mass="32470" checksum="2ED85F06FB2C16F4" modified="2013-11-13" version="1">MTTADEPPARLTRAAAVRASVIVYLKGLAMGAADAVPGISGGTIALITGIYGRLITAVTRLDPRVITSLGDVRTGTGRAALTAQLRHMDVPFLLTLGTGIATAVVIVARGVEAAFASAPGLAYAFFFGLIGASAVVLYEQRWLTRPRLVIASGGGFVVAFVVAGATTSGGPGHGLLVLFVAGAIAVAGMVLPGISGAFLLLLLGQYEYLAETLNTFVDGLTAGVIRKTAVDITAFVAGASIGLFTVAYVVRWALERSRAATLAFLLSLMLGALRLPVEEVDTAVRTWTPVTTGAVLGVAVLGASVGLLMNTATENGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAR8</accession>
    <name>U1PAR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ATPase involved in replication control, Cdc46/Mcm family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01345</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89191">
        <property type="protein sequence ID" value="ERG89191"/>
        <property type="gene ID" value="J07HX5_01345"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_499335_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="274"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="545" mass="61163" checksum="3B25A6CCE3775997" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAT1</accession>
    <name>U1PAT1_9EURY</name>
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        <submittedName>
            <fullName evidence="8">Phosphate/sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01360</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Potential transporter for phosphate.</text>
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        <subcellularLocation>
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            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:phosphate ion transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
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        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
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        <location>
            <begin position="109"/>
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        </location>
    </feature>
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        </source>
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        <source>
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        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89206.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="286" mass="29054" checksum="A29B9C51216ED418" modified="2013-11-13" version="1">MTGGALATIAVAGLASLFMAWAIGAGSSGSTPFAPAVGADAISILRAGFLVGILGLLGAVLQGANVTEAVGGELVVGDPLSAPAATIALTVAATFVAVGIFAGYPIATAFTVTGAVVGVGIAAGGGPAWDKYTAILTLWVAAPFVGGTSAYATARLLRTDRLSVHQTVPALGAXXXXXXXVRGDPNNGGQVVRAGTPDNRPICNQDPPGRVERSKREFILGMSKVNLARVHGGRMVGKPTIGDRNLVWVHPPVVVGIFRTQVWALNPAIDDGMDNLDPMSTQIGRH</sequence>
</entry>
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    <accession>U1PBI2</accession>
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        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="30"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="304" mass="33747" checksum="E56CEA2CEBF517BA" modified="2013-11-13" version="1">MDHGLTDRLNARFDSYDVLRQLHDVPPHEVYEITVNGQRAIYKANTGPTGRAGMEGRVMAFVEQHSSVSVPETILVENAFYVASWHDDAPSPEPDHHADKDWAHAAGRGLARLHNETAPCVDAYGAFRPDGGLRPGGHDRWHAAAAAYVRSRRPVLAQYGHADMADAVLGYLDEHPDAFAGAGTPVCCHGWATPEHVAVTDGDVACMIDFEHAIAAPDEYDYWRTVVPTFGPAESRLRDVFRTGYESVRSLPSGLERRRRPYALLNGVYYFESLYVQNQHGPEETAQTADRLRTRITEILNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBI6</accession>
    <name>U1PBI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01595</name>
    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89436">
        <property type="protein sequence ID" value="ERG89436"/>
        <property type="gene ID" value="J07HX5_01595"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2748009_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="8036" checksum="06932BD238DC859B" modified="2013-11-13" version="1">MNSLGLSGEYPVIKFKHKRVIIWELSPSHQPAYLCNRCCRNVYICRNRLRSLVCGHYDDGASHCDDNQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBQ0</accession>
    <name>U1PBQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01666</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3245216_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024064">
        <property type="entry name" value="FdhE-like_sf"/>
    </dbReference>
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        <property type="entry name" value="SSF144020"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="4614" checksum="7D8DB9DDE77278D7" modified="2013-11-13" version="1">MARCPHCDHSDEISVEWFADPTSNEHRVITCPSCDAVLGGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBW3</accession>
    <name>U1PBW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01737</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89571">
        <property type="protein sequence ID" value="ERG89571"/>
        <property type="gene ID" value="J07HX5_01737"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1900487_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="134" mass="14758" checksum="2DE79F1E9526D548" modified="2013-11-13" version="1" fragment="single">ASTENGTVLGVDLGVNNLAVASTGTVWTGNEFDHWRQEYENRRGDLQECGTWWAHENVQSVGHKQESRYKITLYRISNELVAEACDHGCSVIAFEDLTDIRERTGVSGNISGHSTVSTSASNTKLQSTVSRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC39</accession>
    <name>U1PC39_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5,10-methylenetetrahydromethanopterin reductase</fullName>
            <ecNumber evidence="4">1.5.98.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Methylene-H(4)MPT reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mer</name>
        <name evidence="6" type="ORF">J07HX5_01827</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-methyl-5,6,7,8-tetrahydromethanopterin + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)</text>
            <dbReference type="Rhea" id="RHEA:21144"/>
            <dbReference type="Rhea" id="RHEA-COMP:12939"/>
            <dbReference type="Rhea" id="RHEA-COMP:14378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57818"/>
            <dbReference type="ChEBI" id="CHEBI:58116"/>
            <dbReference type="ChEBI" id="CHEBI:133980"/>
            <dbReference type="ChEBI" id="CHEBI:139511"/>
            <dbReference type="EC" id="1.5.98.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mer family.</text>
    </comment>
    <dbReference type="EC" id="1.5.98.2" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89656">
        <property type="protein sequence ID" value="ERG89656"/>
        <property type="gene ID" value="J07HX5_01827"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_5_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018537">
        <property type="term" value="F:coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01091">
        <property type="entry name" value="F420_mer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019946">
        <property type="entry name" value="MeH4methanopterin_reductase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="328" mass="34767" checksum="9E4F29C284E8AC78" modified="2013-11-13" version="1">MSDRDGVELTPEHPVEQLAELASSAEAAGFGHGFVSHHYNNRDEFVALTAIATATNQLRIGPGITNPYETHPVTLAARMATIDEFTNGRGVFGIGAGDPSTLTNLGVERDRPLRRVLETMRVARRLWAGERVDHDGTFHADDAGLNFDARRIPTYVGSQGPHMTRMAAKHADGVLYNGSHPRDLAWAADRVAEGTADRPDEHGAFDFLAYASASVAENEAAAREAARPPVAFITAGAPPPLLDRHGLDHDLADQIGDTIAAGEFTEAFGLVTDPMIDAFCAAGTPETVADRFAALLEHADGIVVGSPLGPDPETAISLAGAALRAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC49</accession>
    <name>U1PC49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01837</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89666">
        <property type="protein sequence ID" value="ERG89666"/>
        <property type="gene ID" value="J07HX5_01837"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2204030_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="12959" checksum="65EBFF54C4C8BDC5" modified="2013-11-13" version="1">MRYTYKYHLKPTENQRQQLDFYHDTCRQLYNYVLKEFNEIPNSAGTLPQRVKEIVTQIPDLKEWWTELKSVYSTVRQAAVKRIKHSIKALSELKKRLQRRESQLEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCB6</accession>
    <name>U1PCB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01903</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89731">
        <property type="protein sequence ID" value="ERG89731"/>
        <property type="gene ID" value="J07HX5_01903"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353118_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002855">
        <property type="entry name" value="PPS/PS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038138">
        <property type="entry name" value="PPS/PS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02006">
        <property type="entry name" value="PPS_PS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10039" checksum="BD42FA75F76DAED4" modified="2013-11-13" version="1">MLAVVTTFAAAAAAIEVNLVHRAAERVKRIATHLCAHSVETVREPGPNLQFLRLNHGRSLVDLNGIAAAGMLIMPGGGNRAALADRGTTEVVICSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCS0</accession>
    <name>U1PCS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PGF-CTERM archaeal protein-sorting signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_02048</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89876">
        <property type="protein sequence ID" value="ERG89876"/>
        <property type="gene ID" value="J07HX5_02048"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_379273_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="633"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="655"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="731" mass="74247" checksum="9B9A7ED977640617" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFL1</accession>
    <name>U1MFL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate dehydrogenase/leucine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00055</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87914">
        <property type="protein sequence ID" value="ERG87914"/>
        <property type="gene ID" value="J07HX5_00055"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025763_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="5">
        <location>
            <begin position="139"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="354" mass="37259" checksum="21EEC335C855EFE9" modified="2013-11-13" version="1">MPFDQITEGDHEQVTYFSDTETGLKAIVAIHDTTLGPALGGTRLYDYETEADALADALQLSEAMTYKAAAAGLDLGGGKAVILGGEKVKSGPLLEAYGRIIASLGGRFVTSVDMNTTAADMSVIGRETDNVVGTDNGFGDPSPVTATGIRHAIHTTVEQEYGRRSLDGVEVVVQGLGKVGGALVKQLTAHGATVTVSDLSPATVTRFREEHGVDSVAPEAVYDEPCDLFVPAAIGGVIDDDTVSRLSCDAVVGVANNSLAKRRHAVALDEQDVTYVPDYVANAGGLVTVEQEYRGGSMATAQELVTEIGDRLETMFERADAEDTTLLAAAETYAEQRLTEESGKHDWTAATMPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFP4</accession>
    <name>U1MFP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00110</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87969">
        <property type="protein sequence ID" value="ERG87969"/>
        <property type="gene ID" value="J07HX5_00110"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2730189_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="71" mass="7773" checksum="32D839D1C3C8D149" modified="2013-11-13" version="1">MVVLTDGKENASETLEDVVRDRVGACRNKHDWEFLFIGANQDAALTAEKMGMDANKSLDMAHNDAGAENAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFT5</accession>
    <name>U1MFT5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease Z</fullName>
            <shortName evidence="9">RNase Z</shortName>
            <ecNumber evidence="9">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnz</name>
        <name evidence="12" type="ORF">J07HX5_00165</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="9"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88024">
        <property type="protein sequence ID" value="ERG88024"/>
        <property type="gene ID" value="J07HX5_00165"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="31"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="197"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="300" mass="32857" checksum="099D47A81CC15B40" modified="2013-11-13" version="1">MRITAVGTSGGVPTAQYGTSCVYLNVFGEKLLFDCGEGSQQRLMRYSSSPNVDAVFISHCYADHTLGVPGLVQSLEMNERERPLDIYVPEHRTQRATDLIEGAYEWPSYRIEIHGYNSDEPARRTGDYSVRPFSTPYTEHSHGFCLQETDTREFLVERARALGIDPGPKYGKLQAGQSVTADDGETVAPEDVLSEPTPGRKIVYTGDTRPTAAVVDAASNASLFIYSAMFADEQSERARSTGHSTAAEAGAVASDAGAERLWLTHFSPRHEDDEQRLVAQAEQPFDGEVVAARDGESLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGB4</accession>
    <name>U1MGB4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type transport system involved in multi-copper enzyme maturation, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00392</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88249">
        <property type="protein sequence ID" value="ERG88249"/>
        <property type="gene ID" value="J07HX5_00392"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071765_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="30516" checksum="2EC78D5CA0F2B472" modified="2013-11-13" version="1">MSRQDQSADRPQPQSQPKIQSRSQYWLHVARKDFADAVRSGRLWSFLILFFAIALYLLFNVSGDEAIESFGSVMRLLLPVVAVMAGYMAIVGERETGSIRMMLSLPVKRSDVLIGKYLGRCAVVIFSVFLAFGLAALTAVLRYGGLPINAYGAFLLQAILVGAVFSAIAVGCSASVSSQRRAVSVVIGVILIFQLFWRDIVRELYGTFGGDIEGSTPTLVETADQLSPMTAIDTAVSGLNVISTSELPVFQEWVSAVIIMMWIVGPLTIGYLLFRNSDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGR0</accession>
    <name>U1MGR0_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">J07HX5_00544</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88399">
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        <property type="gene ID" value="J07HX5_00544"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="12656" checksum="7E13B2E26CEF992E" modified="2013-11-13" version="1">MSGLDARASKIYSAPLSRPSSTRNCLNSANSSTAPDCSRSKWSFGDSITTESVKFITTSSGMLNEDNIDGKLPPVDLLLVRGNAASGSASRTATSYPRAAMSRAACAPAGPAPAIATSYCCCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGS7</accession>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="27" mass="2726" checksum="57FBBA2592E76FF3" modified="2013-11-13" version="1" fragment="single">MSTTLTPSGRDPTVCADVSNGASWQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH62</accession>
    <name>U1MH62_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Undecaprenyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_00775</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00775"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
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        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="309" mass="33684" checksum="AD724BD938BE3952" modified="2013-11-13" version="1">MRLGSGSHSDCTASTGGCSRPKSPRHRHTSPSSKMETGDTPTSRERAHTRDTERAPRRPNSCSSGPTSSGLKRSRCMRSRPRTSIDPPTSGQHYLSCSPRSFGSSPTQTAFTSARSGSGASASATGFQSTFARQSRTPSDKLQDYDRLQLNVALAYGGRAELLGAAREIAARVEDGELAPDEIDVETVQTALPDGPTQAVDLIVRTGGDERTSNFLPWQAKGNEAAVYFCAPYWPEFRKIDFMRGLRTYAHREQSWRRSRARRARTLLTALPGEYPDARATLAQFWSALPGEEQEESVDADGLAVDPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHI3</accession>
    <name>U1MHI3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00925</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
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        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="31841" checksum="65931B0AC386AE89" modified="2013-11-13" version="1">MTSVVDVATGFDFLVTGLGKGAVYALIAVGFALIYKVTGVLNFAQGWFAALFAFLPVVFTTPVVVALEVPPLAAVAITVLAGVVVGLALERGIFRYFIGEPVLSVIVVTLALVASIEGLVQYFVGPGFRSYPDALQPDWTVPLLFGVELQAAFAIAIALAVLTVGLLMAFFRYTVSGSILRAAASDQQAAMVLGVSIERTIIIAWTISLTITSIGGVLLAMSSGGASFGPFQSVGILVFAAVVLGGIDSIPGAFVGAIAIGVIEELGSGYLDGPVAPGFGGILPLILLVFIILLLPYGLFGTERIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIE9</accession>
    <name>U1MIE9_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01322</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_01322"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding_C" evidence="1">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18969" checksum="2900A3E50C817A6B" modified="2013-11-13" version="1">MTKSLWSGDERYLEEYWRRFEDTWDHGDWAQRDEDGFWFLHGRSDDVLNVAGRKVGPAEVEGALIDHDAVSAAAAVGADDDTTGTAVIAYVILEAGYPETDTLRTQLREQVGAELGKPFRPREILFVDEFPKTQSGKIVRRLIADVYAGAEPGDLSSIENPAALETLAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MII1</accession>
    <name>U1MII1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Acidic ribosomal protein P0 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl10</name>
        <name evidence="2" type="synonym">rplP0</name>
        <name evidence="5" type="ORF">J07HX5_01363</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89209">
        <property type="protein sequence ID" value="ERG89209"/>
        <property type="gene ID" value="J07HX5_01363"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053173_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00280">
        <property type="entry name" value="Ribosomal_L10_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022909">
        <property type="entry name" value="50S_L10_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="RL10_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="RL10P_insert"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RL10P_insert" evidence="4">
        <location>
            <begin position="114"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="349" mass="36727" checksum="1AB634D0E9FB7F1B" modified="2013-11-13" version="1">MSTQRTTETIPEWKRREVDELAAFLDQYESIGVVDITGIPSRQLQQVRRELHETAELRVARNTLIERALKDASRELETLTEHVTGQVGVIGTNNNPFGLYRRLEESKTSAPINAGETAPNDIVVPEGDTGVDPGPFVGDLQNVGANARIEGGSITVLEESTVLEADGTVSDTLAGVLSELGIEPKEVGLDLRGVFADGITFEPSELELDVEQYRTDLTAAAGDARSLAATSGFPASGAVGLVLATASADAKQLGREATLLEPGVIPDLLSRADGQLRALAAQIDDQEALPEELQGADGAATTAESTDTGEQTTEDDTTASEDNTSADDGEGDDDDDDDDTGDALGAMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIP2</accession>
    <name>U1MIP2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01446</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89289">
        <property type="protein sequence ID" value="ERG89289"/>
        <property type="gene ID" value="J07HX5_01446"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3400309_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="32" mass="3438" checksum="B38BF6E6F06A5D53" modified="2013-11-13" version="1" fragment="single">MLATGPSLRALPPPAPRRLPTVLVAWLRAGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIX1</accession>
    <name>U1MIX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01522</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89364">
        <property type="protein sequence ID" value="ERG89364"/>
        <property type="gene ID" value="J07HX5_01522"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_552687_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GAF" evidence="4">
        <location>
            <begin position="117"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="BAT" evidence="5">
        <location>
            <begin position="272"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="431"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="493" mass="53299" checksum="EF3802CF8B6ACFED" modified="2013-11-13" version="1" fragment="single">PIGTVFPESVEAGVLRLFDSTPTTETTIEEYYPGPDRWLSVSVIPMSLTEIEAGSGVSANESTGTETEITTITLYLQEVTDRHRDERRLDRLRGDIDRLTVINELISDILGELVDASTREEIAETICARLGETEIYDFAWVGERELGGDSTVVRAAAGTTGRTFEQIETALDTGASIPEARAIETGMPEIVQPIGADDDVPEAIRRAAFADGLQSLLAVPLVHGTSVYGVVGLYTTNQNAFSARERLSFGTVGEMAGFAVNATRHRNLLLSDTLVELRLQIDDRDDPLVAATAGHDAALSLDGVVPQGDALLCYLTVDTGTPDAIGDRLRAHDATDSVRVVGDDPAGESIEGVLRETTVLARLVARGATVRSGTFDQTGGEVVTDLSPGEDVRRLVAAVTKGYDASVVAKRERQREVTTTREFREALGERLTDRQRTALKTAFLADYFESPRESTAEEVAEALDITGPTLLYHLRASQRKLLAEVFDTDGDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIX8</accession>
    <name>U1MIX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01532</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89374">
        <property type="protein sequence ID" value="ERG89374"/>
        <property type="gene ID" value="J07HX5_01532"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930080_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6778" checksum="D633D9F4E0CBB88B" modified="2013-11-13" version="1">MVCREVLSTTPHRTLVAIMLAPETNLCVGKVRQLCRQVLDYPGRGLRYAITADEYTANRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIY3</accession>
    <name>U1MIY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine synthase II (Cobalamin-independent)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01537</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89379">
        <property type="protein sequence ID" value="ERG89379"/>
        <property type="gene ID" value="J07HX5_01537"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046993_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="178"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="385" mass="41840" checksum="7A5C4AB0694FA3DC" modified="2013-11-13" version="1">MHHEPEQILSTHVGSLPRSAELLPFYEAREAGEETDTEAFQHAVASATEAVVEQQHGAGIDIASHGEQGRPSFVTYAVERLTGFDGAVPAVQWADLEAYPEYAQQVPTFSDWSDPDTTIPAATGEISYRGTEQVRAEIDRFDAAVETTGTTFEDRFITAASPGAIASYIGNEYYSTHREYLAAVASAMQTEYELIADAGFTLQIDAPDLLGGNHLKFKDQSEAAFVETARAHIEALNNALRNVPADQVRMHVCWGNYEGPHQHDIPLDSVLPELYEADISGLLVEQATPRHRHEYELFNEYGIPDDWLLIPGVIDVNSNAIEPPAVVADRIEQFVAAVGDPAPVHAGADCGLGTFADFGAVHPPIAWEKLASLAAGAELATDRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ34</accession>
    <name>U1MJ34_9EURY</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">J07HX5_01613</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="54" mass="6348" checksum="EF773FFF54114064" modified="2013-11-13" version="1">MSSIRYENEPDSYTEVEGVEIYYNGSQETFTFDDPDDGSSMEIPRERVYEIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ82</accession>
    <name>U1MJ82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01684</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89519.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89519">
        <property type="protein sequence ID" value="ERG89519"/>
        <property type="gene ID" value="J07HX5_01684"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147794_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15591" checksum="315FD452CC17BAB0" modified="2013-11-13" version="1">MSRIPSDHATVTSHPLAIDQVGRTSRLQVPLDPVAPLELTPGAVLSLSLSGTQRYAQLTQTLAGAPALRSAFQTRRLARVEEPTTEDNRLTDWINGADLVAGNRVVFDVLAAGHAYGLRVPGERVVYDPPARPDPDLSDIAEKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJN1</accession>
    <name>U1MJN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01871</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89699">
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        <property type="gene ID" value="J07HX5_01871"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_945281_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="29828" checksum="98567F8EBB6E1DF5" modified="2013-11-13" version="1">MELTGADLSGAVLTDVDLSAADLTAANLTGATVRADVDGAVFRDAVVANTELIETTLPENVARTPASGHPDETPTETVDAEDRHRPETDQREQVSWQQRLVAGSIAGGVSVLVGYLLTLAVVGGFERGTLIRARLFDASGWAYYDAQLVQLEINDPLDSDTQGAFDGDAWNIVTQSGEPRILGVLGVTVLSAVYHLIPVVVLLAAGAVAARSVGVTTVRGGATTGLATVPGSVVAAALGALAFSGQIGGLGLGVSVLESVRWVGVVFPAVFGTAGGVLCGVIAVRGGTGTGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK58</accession>
    <name>U1MK58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative metal-dependent protease of the PAD1/JAB1 superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_02097</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89924">
        <property type="protein sequence ID" value="ERG89924"/>
        <property type="gene ID" value="J07HX5_02097"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116578_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
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        <property type="entry name" value="MPN"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="164" mass="17854" checksum="A19FD70087C5FD41" modified="2013-11-13" version="1">MGLFRSSEIIGIAESALEFARAASEEAHPDEYMGLLRGEAASAVGLDRSGTVLTDVLVIPGTESNPVSATVKTNMVPNDLRAAGSIHSHPNGVLRPSDADLATFTRNDVHIILGAPYGRENWRAFDREGTPIDLPMLDIDPPEETFFDFTQADIDRQFTEEDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV56</accession>
    <name>U1MV56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
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            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87965">
        <property type="protein sequence ID" value="ERG87965"/>
        <property type="gene ID" value="J07HX5_00106"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2115395_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="114" mass="12090" checksum="EB66041C7FCD257E" modified="2013-11-13" version="1">MPLLFHQQSCFDQFGPCRLASGSIIIYPSLSGSGQNSQNQRIFLLGSLGAVSCRLAQITGRWVGQSQLADGEDLGVTLIRRLVFGVCGGTARFEYATQSTDSPTAPAGGISNKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVC0</accession>
    <name>U1MVC0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00039</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87898">
        <property type="protein sequence ID" value="ERG87898"/>
        <property type="gene ID" value="J07HX5_00039"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163976_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025336">
        <property type="entry name" value="DUF4242"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14026">
        <property type="entry name" value="DUF4242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11604" checksum="2D1CBD359DD15204" modified="2013-11-13" version="1">MSDQELNDFGIWREMDADITDEEAKQEALEASQGAIQELAQEGVEVEWVSTDVLEDPESDSECAYCHYRAPSEEAIKEHSERAGLPVTKLTRMDDQLDKEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVC5</accession>
    <name>U1MVC5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CobQ/CobB/MinD/ParA nucleotide binding domain protein (DUF59)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00196</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88055">
        <property type="protein sequence ID" value="ERG88055"/>
        <property type="gene ID" value="J07HX5_00196"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1369485_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="20401" checksum="454AD95855E24086" modified="2013-11-13" version="1">MFATVSLGDGLALIMNVTAKMVREQLETVNDPELEADLVTLGLVNNVQIDHNRSAVTVDLALGAPYSPAETAIAGRVQDALADLPYEVELSATVTHGQSGPLAAVKNVIVVASGKGGVGKSTIASNLAAGLADLGATVGLLDADVYGPNAPSLLGGDGPPALTDDEMLLPPERFGVRVMSMDFLVGQDDPVIFPRPDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVG2</accession>
    <name>U1MVG2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00094</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87953">
        <property type="protein sequence ID" value="ERG87953"/>
        <property type="gene ID" value="J07HX5_00094"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1076067_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="27277" checksum="745B8E547030BD3A" modified="2013-11-13" version="1">MIGFGGPDVIGTTSASQSVWLDAYIYVNEAGAQESMAHEAKDALETLFEHVGNSGHCDFDYTVYNRYDTQASDGEYPSVGAGEIHAWEDWLTDQGHTEGADSGEAAVHHLVRHDASVTGGGKGWGGRVCWPDDISLNPTMSTASGADDWHRLTVQHEVGHQMIDATISRVDEKTHSSAAECQHADDGETIHNAEHTLGTVVDGGKTVMAHRSPTAAECDGGGDGSGVGDNNAHGTGITPDRTSHAADKAFGITKREHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVG3</accession>
    <name>U1MVG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00242</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88100">
        <property type="protein sequence ID" value="ERG88100"/>
        <property type="gene ID" value="J07HX5_00242"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_208210_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="7059" checksum="ACB0DC30CCD570D4" modified="2013-11-13" version="1">MSISKYIDIYMLNGFEIDNKEVLDNKLKEFGNSVHVAVSKRWRGAAVKLVRASEPTESTDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVK9</accession>
    <name>U1MVK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00293</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88150">
        <property type="protein sequence ID" value="ERG88150"/>
        <property type="gene ID" value="J07HX5_00293"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2550100_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8862" checksum="FACAB5CC845D9083" modified="2013-11-13" version="1">MIDDDERSLVASTIDLTPGRSTLDSTLAEHWPGQLRTGGARTGCEPGAIIPAGDCWSVAVRQARVQGGQSPSFFVCRYELWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVN3</accession>
    <name>U1MVN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00169</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88028">
        <property type="protein sequence ID" value="ERG88028"/>
        <property type="gene ID" value="J07HX5_00169"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2140120_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="12075" checksum="E53B210D706E0E57" modified="2013-11-13" version="1">MNIGGHDIDTEQVAGVEIPATCRDRIDDDVLKAAVEILDAHQMTDYTVSPVGGLKIRVGVHRPNTAYVALRDELHTLDAPVTEHGVSDGVRRLRLGLTSETDETAASSTQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVN7</accession>
    <name>U1MVN7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00323</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88180">
        <property type="protein sequence ID" value="ERG88180"/>
        <property type="gene ID" value="J07HX5_00323"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1028525_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="8">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="9">
        <location>
            <begin position="130"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="30512" checksum="7D7F13F9396FF353" modified="2013-11-13" version="1" fragment="single">RDGNGEIIHVIGKDIIQQHTVFWPAMLKGAGYAEPRAITATGFVTLDDKGVSTSRNRAIWAEEILDEGFHPDPVRYYLISAGNIQRDIDFTWESFAEQVNTDLVGCIGNFLYRSLVFAHRYWDGTPAVSDSHKINGEIESAMGKFQRALNNYSLRTVSEIPLELARFGNKYIQKHEPWKLIDESPDQAARVLRDCVQLTKAIAILFEPIAPEKAETLWTQLGEDGSVHKATIEESTTSPPNQFGEPQKLFKQIEDDRVVELKKKLQAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVV7</accession>
    <name>U1MVV7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="2">RPPK</shortName>
            <ecNumber evidence="2">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="2">P-Rib-PP synthase</shortName>
            <shortName evidence="2">PRPP synthase</shortName>
            <shortName evidence="2">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prs</name>
        <name evidence="6" type="ORF">J07HX5_00393</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88250">
        <property type="protein sequence ID" value="ERG88250"/>
        <property type="gene ID" value="J07HX5_00393"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_2_2_2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_A">
        <property type="entry name" value="RibP_PPkinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037514">
        <property type="entry name" value="Rib-P_diPkinase_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="4">
        <location>
            <begin position="137"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="33"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="88"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="283" mass="29814" checksum="749C6B1C53D9D92E" modified="2013-11-13" version="1">MIVSGSRTQSLAAALADQTRHELADVSFDRFPDGEGIVRIDDAPTHAVVVASTVSDRAHIELLQLQDAVREAGADRVTTVLPYMGYARQDRPFDAGQPVSARAVARAISTGSTRVLVVEPHERSVCDWFTVPATAVDAAERLAVGLSAEDPLVVAPDAGATDLARSVRDAHGTGECAHFEKRRYSDTDVELEFASAETVADRQVVLVDDIVATGGTMCEAARLLTDRGAAQVTVACVHPLLVRGAHLKLLRAGVDTVIGTDTIEQPMSTVTVAPAIAGALSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVZ7</accession>
    <name>U1MVZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00301</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88158">
        <property type="protein sequence ID" value="ERG88158"/>
        <property type="gene ID" value="J07HX5_00301"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3263657_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4495" checksum="4F4C841AFE7FFA13" modified="2013-11-13" version="1">MTGQLDRQWADVGVRTNADCVCSRETNYQGVNMGGNVDADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW77</accession>
    <name>U1MW77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00504</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88360">
        <property type="protein sequence ID" value="ERG88360"/>
        <property type="gene ID" value="J07HX5_00504"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071766_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="302" mass="32482" checksum="2C40ED3D9CE6C469" modified="2013-11-13" version="1">MLATGRVMRLERFDGVDGLFAATQTGLYRRTAGDWTDLSVPREQVYAVGAAQTGRLFAGTRPAAVYTTPSAAAPNWQECAGFQELPSREEWRLPRHEQLAQVRDIHVVADPDAAAGANASGDADEQLRVVAGVEVGGVHHSADRGVTWRERRTGGSDDIHELHVAKPGEHVYVAATGGGLYRSRDAGRSWARLDTAIEQDYFRTAHTHDGTVYAGGAMANSSTWNDPDADPQLVAVRDGSLEPIEIPFPDETVTGLATIGASLHAVTHCGRVLQREGPDWTELATVPTPRPVTGRYTPLTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWB9</accession>
    <name>U1MWB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00421</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00421"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1017819_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="273" mass="31038" checksum="DA36016C483023C9" modified="2013-11-13" version="1">MTERWSVSWSHTSSVSAHNSTVRCHVLIFNELSVTFIQIKLELCFVSYQIHLYASDELQSHCEDEHNNPTQAIDRMETYLEHAYDRMGADSSVTAKDDRVHAPDQNFTDPFTTYQPCDTTYKKSYDGLLDWWAEHAQAYCNDRDNADFCNILVTAGRGDNDNPLISGGQADMSHFAVCVTGIMAAKVPASYQEYGMGGEYRAVRTPHHELGHQMMGYVNHSHDKGATFRNGTPDHYMTPMYVQGEQNDCGEAQSTFGSRGWEQKWSDCCEKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWE5</accession>
    <name>U1MWE5_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00446</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88303.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88303">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0032196">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
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        <property type="entry name" value="OrfB_Zn_ribbon"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="41"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="12959" checksum="52D7E99DBC9645BC" modified="2013-11-13" version="1" fragment="single">MNDLIKEAQDATVDVIGFENLDHIHENIANSSQSQQWACAKFVELVEYRIGSTTLFVDFVNPAYTSQRCSHCRLTHEDNRDDKQFACQGCKYELNADYNAAKNIVVQYCGYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWG7</accession>
    <name>U1MWG7_9EURY</name>
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        </submittedName>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88323.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88323">
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        <property type="gene ID" value="J07HX5_00467"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3000682_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="5869" checksum="FEA4059FF6BF0E53" modified="2013-11-13" version="1" fragment="single">LSMRSPSTTTTARNWSRESYAGAGEQLSVSTATKFVLLAVSLTILAGLAIVVALAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWL7</accession>
    <name>U1MWL7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD_assoc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00681</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="15"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="251" mass="27873" checksum="8D280AB2B0B33A05" modified="2013-11-13" version="1" fragment="single">LVRDAHHTGVPYGTIDHERLIRALRLVDNELVLDEGNVQTAESLLLARALMNPTVYAHHVARIAKAMLRQASERLLESGTVDAHTLRRMDDYGLRTALRECNATQKFARRLDTRQLYKRAAWAELDAVPDSLLTADHNQIQTLERDVAEAAGVDPTSVIIDLPPPPSMAETTSQVMINGDVRQLEDQSALVGALRQAQTDNWRLGIYSPGDDRDRVRDAVVRELGLDRRATTIPNARSGVNATLDAFADRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWQ1</accession>
    <name>U1MWQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00543</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88398">
        <property type="protein sequence ID" value="ERG88398"/>
        <property type="gene ID" value="J07HX5_00543"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3408333_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="29" mass="2997" checksum="DA522A0DD371896E" modified="2013-11-13" version="1">MLSADVSDSENDSARSATDAAARADFIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWQ7</accession>
    <name>U1MWQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dolichol kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00731</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88585">
        <property type="protein sequence ID" value="ERG88585"/>
        <property type="gene ID" value="J07HX5_00731"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089196_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="20236" checksum="BB8B814A678244D8" modified="2013-11-13" version="1">MAGGTSVEDTTRLRGELGRRVVHASGAVLPVAHVAGLVTWPQVTALLVAGTAVAALLEAVRLSTGLEWFVYQHLTREYEQEIVAGYALYLGSSAAVAVAFEATIAIPAILMLALADPLSGLASSGGLKRMKRPRALAVMFCVSAVVATPFVPPAVAVAGATAATAADGVTLAVGSRIIDDNLTIPLTAAVTMQTGQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWV2</accession>
    <name>U1MWV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00598</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
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            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG88453.1"/>
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        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="13619" checksum="8926CB1AEEE016C5" modified="2013-11-13" version="1" fragment="single">ALVFFPMDGAFPATYMWTELRDRAWTDRSATVVGVSVSSPYEHSTFIDRYELPYRLFSDPSNSIAETYGVVHDLDGMAGVTEPRPAVFLIGDDQTVQYAWAATEWPSFPPYDEIEAAIDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX35</accession>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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            <dbReference type="EMBL" id="ERG88543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6778" checksum="08060348CDA983B8" modified="2013-11-13" version="1">MLAGQHGCVRYQTLDGVSIIAFHSKRWGGGVWAFSGLLMGYINQTELPLRLHMSDAQLSNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXB9</accession>
    <name>U1MXB9_9EURY</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88638.1"/>
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    </dbReference>
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    </dbReference>
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            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="38" mass="4148" checksum="CFE6998DE1B4941C" modified="2013-11-13" version="1" fragment="single">TAWLASSQLASFGMQIAIDIVRPINEQMPTIDRTGIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXF7</accession>
    <name>U1MXF7_9EURY</name>
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        <submittedName>
            <fullName evidence="3">RimK-like ATP-grasp domain protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_00976</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88830">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATP_grasp_subdomain_1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="93"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="157" mass="17196" checksum="3EA62AE49B11478A" modified="2013-11-13" version="1">MNVGLLYSRIRRDEKLLLTELRDRGHETTKLDVRDQRFGLTGAATPLDVDLLVDRCLATSRSLYATRFAAAYDVPVVNAAETARVCANKVETSLALANADVPTPTTEVAFTVESALTAVESFGYPCVLKPVIGSWGRLLAKIESRSAAEAIFEHKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY19</accession>
    <name>U1MY19_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_01212</name>
    </gene>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89060">
        <property type="protein sequence ID" value="ERG89060"/>
        <property type="gene ID" value="J07HX5_01212"/>
    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG89060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="4944" checksum="A409C11F1CCF6AE5" modified="2013-11-13" version="1">MLSCPVIKSLRLLSTGWSGLGGHVGLVDLVEAAGSPPDGAVGDRPLTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY43</accession>
    <name>U1MY43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01080</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="3"/>
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        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="30414" checksum="E7F3D21005B3D101" modified="2013-11-13" version="1">MLATLLSPTNGTVQINGFDTQSAAASVRETIGYMAQETSIDPELTAAENIRFACEAYGVPRGDRPDRVAELLDLVDLADVADKEAEEFSGGMKKRLDAATALVHQPPLVFLDEPTTGLDPKARNRLWDYFLRINDRGTTVFLTTQYLEEADQLCDRLAVILDGEIVVEGSPADLKREVGGEVLDIELADETTQQTQAVTIAKEFDAFGDAAVAETETGISVTAETVREHGTDLLVAFRDAGVTVTGFNIRAPTLDDVFLAITGDELALEETDEQRMEVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY50</accession>
    <name>U1MY50_9EURY</name>
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        <submittedName>
            <fullName evidence="7">F0F1-type ATP synthase, subunit c/archaeal/vacuolar-type H+-ATPase, subunit K</fullName>
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    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01247</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89095">
        <property type="protein sequence ID" value="ERG89095"/>
        <property type="gene ID" value="J07HX5_01247"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2327168_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="6">
        <location>
            <begin position="37"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="10090" checksum="D09AECB7F162FE5F" modified="2013-11-13" version="1">MIEFLPDVASSLETVFASTQPRSPEYASNLAEGLTNLAVGIAIGLAALATGLAQRSIGSAAVGSVSEDSGNLAYALVFTVIPETLIIFGFLTIFLLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY83</accession>
    <name>U1MY83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01128</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88978">
        <property type="protein sequence ID" value="ERG88978"/>
        <property type="gene ID" value="J07HX5_01128"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_805623_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SERPIN" evidence="3">
        <location>
            <begin position="61"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="344" mass="38309" checksum="93159548241E8593" modified="2013-11-13" version="1">MERRQLLAVSGALLAGAVAGCTESSRLEKPGKPKQAPATTLASLDNAALETLVAQTNGFTIDLHRQLLADRSDENVFSSPISASMAFAMTYAGARGETRQQLREAFRYPEESLHATMGKLQSRLNQRGRETNETTSTDSTDDTSEEETTDSVEQPESDGTAFQLSIANAVWGQERFSFKRSYRDTLTEAYGSTLREAAFVENAADERERINDWVADETDDTIGELLPQGALGSRTRLVLVNAIYFLANWTHTFPEDATTDKTFSALDGTDHDVPMMSLKREGLHRTRRRASDRVALRRRRHSHDRRAAPSRRVRGLRTTARRPTARRTDRRARATIGHCPAPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYD7</accession>
    <name>U1MYD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01338</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89185">
        <property type="protein sequence ID" value="ERG89185"/>
        <property type="gene ID" value="J07HX5_01338"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3194369_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="45" mass="4992" checksum="561683C912536D96" modified="2013-11-13" version="1">MKADESDKKKYDAAFDRGDNTTARENMTADLAVPTCVLDSKMCMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYN1</accession>
    <name>U1MYN1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01291</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeoC/FbaB aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89138">
        <property type="protein sequence ID" value="ERG89138"/>
        <property type="gene ID" value="J07HX5_01291"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057069_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010210">
        <property type="entry name" value="ADH_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038992">
        <property type="entry name" value="Aldolase_Ia"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01949">
        <property type="entry name" value="AroFGH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="26841" checksum="64936EA269ED1F0C" modified="2013-11-13" version="1">MRRLSTAERYLTVPMDHGLTLGPVAGLADIESTIDAVTSAGADAVLTQRGIAPRVHENANNAGYIVHLNGSTTIGPDENDKRPTGTVEDAVRAGADAVSFHINVGSDHEPAQIEQLAEITSDAATYGLPVLAMTYARGASVSDPEQAEAYADDLAHAVRLGEELGADLVKTQYSGDPDSFRRVVEATRLPVLIAGGSKATDAETLSMVAGAITAGAAGVSMGRSIFQHEDPVAITAAVSAIVHDDADTEEAASVAGLAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYR5</accession>
    <name>U1MYR5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Isopentenyl phosphate kinase</fullName>
            <shortName evidence="6">IPK</shortName>
            <ecNumber evidence="3 6">2.7.4.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01473</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33963"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:65078"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.26"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the isopentenyl phosphate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.26" evidence="3 6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89315">
        <property type="protein sequence ID" value="ERG89315"/>
        <property type="gene ID" value="J07HX5_01473"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070213_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102043">
        <property type="term" value="F:isopentenyl phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04241">
        <property type="entry name" value="AAK_FomA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024192">
        <property type="entry name" value="Fosfomycin_R_FomA-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF1">
        <property type="entry name" value="PTHR43654:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016496">
        <property type="entry name" value="Kin_FomA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="6"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010540"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012908"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00017267"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR016496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR016496-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016496-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="27709" checksum="E9909FB0F3C473EB" modified="2013-11-13" version="1">MTTILKLGGSVVTEKAVPETVDEGALETAASALGADPPDSLVLVHGGGSFGHHYADAHDVSAQAGTTDPAAVAAIHAAMGELNAAVVDALQTKGLPAVPVRPLSAASKRPGDSHTNRVDHADTTPEAAAERDHRPAPLENDAADSVELMTGPVQALLAEEFVPVLHGDVVATRGRGCTIASGDALVAALSTALSPTRVGLCTTVPGVLDADDRVIDEIDRLAAVTDVLGGADTTDVTGGMAGKIETLLAIEADASVFGLEALPTFLAMGAAGTVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYZ3</accession>
    <name>U1MYZ3_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_01420</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89263">
        <property type="protein sequence ID" value="ERG89263"/>
        <property type="gene ID" value="J07HX5_01420"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1931849_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="160" mass="18091" checksum="D2AA73303E6EB89A" modified="2013-11-13" version="1">MRTDCRPCQALYPRQIPVVGSIQYRSEAVCPTLNSSKHTTLSPEPVCDEPSTDRGRSVDLWAMSREQPSGSTREYPTERTEICAHITFRRTDNNTPLGNHKIARDESSCGSKCGVFGRMARRVKHRYVVSSXXXXXXXATAQGRPVWRQLRLPRTACPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ07</accession>
    <name>U1MZ07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01553</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_01553"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_817859_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="37466" checksum="37ABEC321A8EF640" modified="2013-11-13" version="1">METRPALADWASVDSSWGSCLSAYTVGDQPELGTLTPEHAARRWQTVETWTDAYATSESVVQTGRSRTIVGNERLAATWESITPWWNSYTDTGHETARQLAATLAGSTAEWVAADGPFEADPPASDLTRSPVSRGPVQPGTEVEWSRWLAQLLCPSAALVRALFAGQVTQPLEEVTREDRLPRETGGFRRADLVVQQAAQGVSIEIKLDDRNCERTAETAALVEEKYEHREWEHVLLLPARHRKRLERIVTGQSRRQPTVQSKSCDESRDRSKCCAGAMSPAPCSRCSGAARSSTTTRHRTHTCSVRCSNSSCSGSDRVQRSNGWHSRQMSSIRSVPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ60</accession>
    <name>U1MZ60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01491</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89333">
        <property type="protein sequence ID" value="ERG89333"/>
        <property type="gene ID" value="J07HX5_01491"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2890796_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6813" checksum="236B9065CC1F9A23" modified="2013-11-13" version="1" fragment="single">DEFNDSSEIDPVVKIGESAFRFQIDPQGADRVRLVTKVPAHAKPGFYNVTGRIEPIDGVPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ66</accession>
    <name>U1MZ66_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <shortName evidence="1">MTA/SAH deaminase</shortName>
            <ecNumber evidence="1">3.5.4.28</ecNumber>
            <ecNumber evidence="1">3.5.4.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtaD</name>
        <name evidence="3" type="ORF">J07HX5_01496</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20716"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57985"/>
            <dbReference type="EC" id="3.5.4.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine</text>
            <dbReference type="Rhea" id="RHEA:25025"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:48595"/>
            <dbReference type="EC" id="3.5.4.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="1"/>
    <dbReference type="EC" id="3.5.4.31" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89338">
        <property type="protein sequence ID" value="ERG89338"/>
        <property type="gene ID" value="J07HX5_01496"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090614">
        <property type="term" value="F:5'-methylthioadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01281">
        <property type="entry name" value="MTA_SAH_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023512">
        <property type="entry name" value="Deaminase_MtaD/DadD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="53"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="431" mass="45500" checksum="4555584B6B257531" modified="2013-11-13" version="1">MSQLLIAGGTVLRPDMSVDRADVLVDREAGTIETVGAPGSLTGDDRLDATDGLVIPGLINAHTHVAMTLFRGAADDKPLDAWLREDIWPVEAALEPTDVQAGTRLGLAEMIRSGTTAFADMYFQMDVVADAVAAAGLRARLGRGCLSVGKDETTAHRDFEDSIAFATEYDGAADGRVQTMVAPHSLTTVGKAFFREYKPRIRAAGLPVHFHANETTAEVDPIVKEHGQRPLAYADELGLLENTHIAHGVHVDDQEIELLAERNTPVAHCPASNMKLASGMAPVAELREAGVTVALGTDGAGSNNDLDMFDEMRDAAMVGKLAADDASAVPAPAVVEMATAGGAAALGIDSGRIEAGANADLAVIDLAAPHLTPQHNLVSHLVYAARGSDVRHTICDGQVLMRDQTLLTIDEERVKEEASERAKALFARADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ87</accession>
    <name>U1MZ87_9EURY</name>
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        <submittedName>
            <fullName evidence="4">Putative membrane protein (DUF2078)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01675</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89510">
        <property type="protein sequence ID" value="ERG89510"/>
        <property type="gene ID" value="J07HX5_01675"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137730_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="3">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="153" mass="16823" checksum="8464C5C02DC12433" modified="2013-11-13" version="1">MPEGGSADDQGPSLESVVSSLVIAATLILAFVLLAAGWEWFWIVFIIGFAGVLPMVPTLAAWYKSKNKDEDRSSSTDERDPLETLRDRYARGDIDEAELERRLDALLETEPDTETGTGTGTEIDTDRLSRTLNTNTDADTDTGAERELDPSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZG0</accession>
    <name>U1MZG0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glucose-6-phosphate isomerase</fullName>
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        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pgi</name>
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    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89595">
        <property type="protein sequence ID" value="ERG89595"/>
        <property type="gene ID" value="J07HX5_01761"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037303_1_0_2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="432" mass="44895" checksum="8E86821AA24F98AE" modified="2013-11-13" version="1">MRVDIGNALATVATPGVATVALEDLDDRVTAAHKQISTQRSTDTFGYAALNLPEQADADAIGDAIAGVADAAAVLTVGIGGSALGATTVSAATGPHETTHTALDNVDPASVTATLDRLPLTKTAVHVVSRSGTTTETLANFRVVRAAMEQAGVDWTERTVVTTGPDGPLRTLAREHGLPTLPVPEGVPGRFAALSPVGLVPAAIQGVDISAVLTGGRAGAASLAPSLFDCPAYAYGAVAYALGQRGARSNVVMPYAERLEPFAEWFAQLWAESLGKDGRGQTPVRALGATDQHSQLQLYRAGPRDKLVTLVQPRDREDRAIPATGADELAYLDGASLGAVLDAEFEATEASLAAAGRPTVRVEIDRLGPESVGRLLYMMEAACVLVGELADVETFTQPAVEWGKRATQGLLAESPMTSETAAVSDKTQYYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZK5</accession>
    <name>U1MZK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01639</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89478">
        <property type="protein sequence ID" value="ERG89478"/>
        <property type="gene ID" value="J07HX5_01639"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3302611_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="3858" checksum="C190947A468FA10A" modified="2013-11-13" version="1">MTQLGLQPVTAGPVADTIDSLGVPCAGTIADLLLFTGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZR9</accession>
    <name>U1MZR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative exporters of the RND superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01719</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89553">
        <property type="protein sequence ID" value="ERG89553"/>
        <property type="gene ID" value="J07HX5_01719"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_562061_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
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</entry>
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                <person name="Narasingarao P."/>
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</entry>
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</entry>
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                <person name="Narasingarao P."/>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="556" mass="58216" checksum="647849F02AA9B71E" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0C9</accession>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89895">
        <property type="protein sequence ID" value="ERG89895"/>
        <property type="gene ID" value="J07HX5_02068"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="304" mass="33117" checksum="47F2F1B2677DF09E" modified="2013-11-13" version="1">MSDDAENTQSTAVNTDPVGSFETLGHELRLAVIKQLAARQRANEWEPISMSFGDLRAAVGADDSGQFNYHLSKLVGPYVEQTDEGYVLTPAGYEVSAAVLAGSHAESEIGPVEGALGYDCPLCETRLRAHYDDGYVSVLCPEDGYLFGNTVPPAAVVGHDIETVVILAVQDLQRTVETAAAGVCPECYSNVKTTLPTESPRLTGDTYRSEDGVYARFECDYCGLTFDTRAATVILGHPAVVSFYYDHDVDVRERGYTETKDTVETVLSEDPPRTQVELNFEDDRLVAVLDGDARLVEAERQTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0Y2</accession>
    <name>U1N0Y2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Prefoldin subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">GimC subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pfdB</name>
        <name evidence="9" type="ORF">J07HX5_02151</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 7">Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterohexamer of two alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89978">
        <property type="protein sequence ID" value="ERG89978"/>
        <property type="gene ID" value="J07HX5_02151"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131909_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00307">
        <property type="entry name" value="PfdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012713">
        <property type="entry name" value="PfdB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02338">
        <property type="entry name" value="gimC_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="15477" checksum="2D8FF81D79335A58" modified="2013-11-13" version="1">MRGFNAAGGLFSGMQGNLPPEAQEKLEELQDLQETAQQVAAQKQEAETQLTESQTALEQLDEIDEETTMYRQLGELLVETEYDEAQTDLESTVDTLEVRVETLEKQEERVQQQFEQLQSELQQMLGGAAGGLGGAGPGAGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P387</accession>
    <name>U1P387_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00093</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87952">
        <property type="protein sequence ID" value="ERG87952"/>
        <property type="gene ID" value="J07HX5_00093"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027480_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="356" mass="37864" checksum="D9F726C479503F6F" modified="2013-11-13" version="1" fragment="single">MPRDNKTPSAQATNTREPKQIISRRRLLQATGAGLITTAGAGAGAAARSDNQQQPRWSTDLAGAACFPPLIANGTVYIGAEPSDYYCTVSAFDVDSGRQQGTLSTSRMRSLSAPAVVDGTVYIGDRDTVHVLNSTLSKLQRIERLGSYTRTPPVVTDGSVYIGCDDGIHALRLDPQRTEHIFTTQAAVRSLCVEDGTVYFGDEDWKVHAVDTSSGTQQWVREISGHPGSPVVDNGVVYVGATSTISGGTSRFYAIDADTGDELWRKEDHGARSPTIVDDTIVTSGDGVCGLNPESGATRWQFTDIQIGTGSPAVSDGTAYVPSFFTEQLYGLEVTTGAVSQTYEIDEDIATPVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P389</accession>
    <name>U1P389_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00098</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87957">
        <property type="protein sequence ID" value="ERG87957"/>
        <property type="gene ID" value="J07HX5_00098"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112915_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5782" checksum="27157D78E5E94B12" modified="2013-11-13" version="1">MYTLRRVTDTLKFGVSCRSSRCTQLHYSHPTNWLFVVCDGCAQSDTVPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3F6</accession>
    <name>U1P3F6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00173</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88032">
        <property type="protein sequence ID" value="ERG88032"/>
        <property type="gene ID" value="J07HX5_00173"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080231_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="16218" checksum="170EE21B4EA607DA" modified="2013-11-13" version="1">MDHHEIVSNLGDEDTFGWVLDHYPECIMIAAGPAHEKPEEEILFVNKYFEQMTGYSRTEALGKTAKMLQGEETSEHVINELTQNLSEGEHFIGETTNYRKDGEPYRVRWSIDPITPDDEAGVTHWVSIQREMSDDALTTGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3I9</accession>
    <name>U1P3I9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00209</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
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    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4394" checksum="C322CDC2012DB6AB" modified="2013-11-13" version="1">MNYFSLGTHGRKSDYAADWRLEIAVVSHTPCGDVRPDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
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            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
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    </reference>
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        <property type="protein sequence ID" value="ERG88082.1"/>
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    </dbReference>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="271" mass="29598" checksum="84961C1AC1D623BC" modified="2013-11-13" version="1">MRESLPGASSREPVTTDSLVRDLRALGVEAGQTLLVHGSLSSLGWVCGGAPAVVDALREVVTPQGTLVMPTHSPGNMDPGDMTMPPVPDEWHETIRDQMPPYRPDMTPTQGMGAIAETFRSYDDVRRSGHPQVSFAAWGDNAETVTADHSFAYSLSEESPLARVYDLNGDVLFLGTDHGMNTSLHLAEYRSTLDFETVTHAGAVLIDGDRQWVEWNEIDYDDGDFQACGDVFEETHPNAVETGAVGIGDAKLFAQRAIVDFAVEWFEVTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3S7</accession>
    <name>U1P3S7_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">J07HX5_00310</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88167.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Bles03"/>
    </dbReference>
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        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="DUF1917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="SSF55418"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="20738" checksum="96E0BD606D8C2A81" modified="2013-11-13" version="1">MQSPITITEAEQHWLRSRDVSDSPAIGGDQYFAQHNVTRREDSQVDHLPPAETDAVRTIDREALRQEKLIGKWQVTGKPERIEELWPTIVADAEAGVIWAVKAMTGYGYQNLPMYDEYLLTVYTPNYFDRDDVFRVRDRLREAHDITHELYYKPDIYTAKGIDTDTAGEFGLSAPARYID</sequence>
</entry>
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    <accession>U1P4G2</accession>
    <name>U1P4G2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00521</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88377.1"/>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00521"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="5910" checksum="48B0141146EF4C6C" modified="2013-11-13" version="1">MTGPVVGAVAALGLSFEAWLVIGGNIFGLIVVGVIVYQYYQLDSETDSGTGGETDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4H8</accession>
    <name>U1P4H8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00547</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88402">
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        <property type="gene ID" value="J07HX5_00547"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039610_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
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        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
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            <end position="373"/>
        </location>
    </feature>
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        <location>
            <begin position="232"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="402" mass="44011" checksum="DE0D0A61B6CC1D2A" modified="2013-11-13" version="1">MTDASPTAPTERVVALDALRGVALLGILIINVRVFAMPEVVLTNPTAYGDFSGLNYLVWLVGHLFAEQTFLTLFSALFGAGIVLFTESKARDGQPAVELHTRRTAWLLVIGLGHAYLLWYGDILVAYALCGFGAVTVRNWPATKQARAGLALFAVPSVLQVLTGLGTGAAAVADLWEPTTTALGQEIEQYQGGYLDQMAHRLPTALERQTLGFLGTTVWRVGGIILLGMALLKWGVFTNDRSASEYRQMAVGGVTAGVTVILAGVAYIEATDWAADAALFWLQFNYWGSILVAAGYVGLVMRLTDRRPAGRVTQGLAAVGRTAFTNYLLQTVLATSVFYGHGLGLFGQVSRVEAFGVVLAIWAVQVPLSVIWLRRYRYGPVEWVWRRLTYRRREPLRRDRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4V3</accession>
    <name>U1P4V3_9EURY</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88557">
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        <property type="gene ID" value="J07HX5_00703"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="6">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="4">
        <location>
            <begin position="84"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="5">
        <location>
            <begin position="544"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="642" mass="70843" checksum="0C159AB36D1C53C7" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4X4</accession>
    <name>U1P4X4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="1">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00728</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88582">
        <property type="protein sequence ID" value="ERG88582"/>
        <property type="gene ID" value="J07HX5_00728"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="444" mass="47621" checksum="0973946AC73F7CD8" modified="2013-11-13" version="1">MSGHTTGSPYAPHTSAETEAMLAAVGAEQEKELFDVPASVQFNGELGIPSRDEQTVRRELRSTLARNNDVIEFLGRGHYDQYVPSLVDHLADRQEFLTSYTQYQPEVAQGFLQALFEYQSMLVELTGLSVANASMYDAATALGEAATLAARLRSVDGSRVLVPEQLRTEKRSVLENYANGAGLTIEAYPMTDGAVNVEALAATVDGSTVMVYVESPTVRGVIEESLAAIGDIATGVDALFVVGSDPTALAVLEEPAAVGADVVVGDAATLGLGTANGMRLGMFAAREELLRQVPGRLVGASTDETDRRAFTLTLQTREQHIRRERATSNICTNQAWVGLRTAIHAAMLGPDGLIERAGASIDRASALADRVDTISGLEAPVHDRHHFREFVVRTDRPAQAIADELADHGIVVHVVDDHLLQLCVTETNAHTVDTLVARLREVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P520</accession>
    <name>U1P520_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00783</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88637">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7333" checksum="256DC359E7C252AE" modified="2013-11-13" version="1" fragment="single">GLDFAPAGELYNFQFDRVVGLATLQEQLETAIETPGAHVIEAVVDGEQSHRVREQLQEDLLTRVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P562</accession>
    <name>U1P562_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DhnA-type fructose-1,6-bisphosphate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00833</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88687">
        <property type="protein sequence ID" value="ERG88687"/>
        <property type="gene ID" value="J07HX5_00833"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057069_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="20652" checksum="D5FB27328F9A0D05" modified="2013-11-13" version="1">MTLLAKLNGASNLWMGEPDSAVNWSVEYAAEVGADVIGFTLYGGSNHEIEMAEEFRGAQEAAREHDLPVVLWSYPRGQGVKNDTDPGVIAYAAREALELGADVAKVKYPGSKAAMQEVVRMASPTKVIVSGGSKTDDRAFLERVRAVMDVGGAGLAVGRNVFQRDNPEAILDALEQIIFEQADVDTALAAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5I6</accession>
    <name>U1P5I6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00943</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88797">
        <property type="protein sequence ID" value="ERG88797"/>
        <property type="gene ID" value="J07HX5_00943"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712649_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7911" checksum="574F78EEFE315663" modified="2013-11-13" version="1">MSMLAALSAVTVSVSVISDKSFFSTVKYLLGRIMSHAPSVNSAVSVIHATPHVVPEWFHLLLWYPLTQPTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5N9</accession>
    <name>U1P5N9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator with C-terminal CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00993</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88847">
        <property type="protein sequence ID" value="ERG88847"/>
        <property type="gene ID" value="J07HX5_00993"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116133_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017158">
        <property type="entry name" value="Tscrpt-reg_CBS-contain_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037253">
        <property type="entry name" value="HTH_CBS_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="70"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19216" checksum="73615B50574DCF3F" modified="2013-11-13" version="1">MKLPTPEDLCDRRKELGLTQAELAERADVSQPLIARIEGDDVDPRLSTLRGIVTALEAAEDGITEARDLMNSPVVGVAPDDSVHQTKGLMDEKGYSQAPVIRDGAPQGLICDSDILQRREENIGTLPVAEVMNESIATVEPQTPLDMVESHLTHSDAVLVVDGGTTVGVITEADVASHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6F6</accession>
    <name>U1P6F6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Probable thymidylate kinase</fullName>
            <ecNumber evidence="2 4">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tmk</name>
        <name evidence="6" type="ORF">J07HX5_01305</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="2 4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89152">
        <property type="protein sequence ID" value="ERG89152"/>
        <property type="gene ID" value="J07HX5_01305"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="5">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="22149" checksum="E62FBCC82954A6F8" modified="2013-11-13" version="1">MLVTLEGLDGSGKTSCVETLQTAPSVPAATYTREPTRSWYGEAVRRSINDDTADPLAEVFLFTADHAAHLAETVRPALSRGEVVVSDRYSDSRYAYQGATLTDRFDSPVEFIRQLHRPWTRPPDTTLYLDVDPATAAQRSGVTDKFETTEYLEQVQNNYEQLLAADPGRFVRIDAAADLETVTQRVVETMTQLVEAETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6W4</accession>
    <name>U1P6W4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Citrate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01470</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89312">
        <property type="protein sequence ID" value="ERG89312"/>
        <property type="gene ID" value="J07HX5_01470"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2230277_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11486" checksum="5E71F0155DE0AEAE" modified="2013-11-13" version="1">MDNTLRRGLDGVVVDETTLSDVDGEAGRLIYRGYEIDDLATHASYEEVLYLLWHGHLPTQTELEKFTEATAADRAIDQSVITLLNSAAAADETPIAXXXXXXXVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P722</accession>
    <name>U1P722_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CTP synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="4">6.3.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00052</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTP synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87911">
        <property type="protein sequence ID" value="ERG87911"/>
        <property type="gene ID" value="J07HX5_00052"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011675_5_0_2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="274"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG87911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="500" mass="54590" checksum="BEED76DA28B5811B" modified="2013-11-13" version="1">MLATAGFDVTAVKIDPYLNVDAGTMNPFEHGEVYVLKDGAEVDLDLGNYERFLGVDMTAEHNITTGKVYQHVISNERAGEYLGRTVQIIPHVTDEIKRRIREPAAGTDVCIVEVGGTVGDIEGMQHLEALRQFAGEQSAEDILFVHVTLVPYSKNGEQKTKPTQHSVKELRSIGLQPDAIVGRSEQPLTAEAREKIALFCDVPRDAVFSNADAEDIYRVPLSLESEGIDEYILSELGLSDAATPPEQRDTAWRERVTQDPTDELRIALVGKYGLEDAYISVHEALKHAGLEHRVAVQSEWIHADQLVDGHGGELAGLDGLIVPGGFGARATEGKIAAIRYARRTGLPFLGLCLGFQMAVVEFARDVLGLDDAHSAELDEGTPHPVIDLLPEQEGVDELGGTMRLGTHQTSITTGSLASRLYGDQCTERHRHRYEVNPAYIDDLENAGLVFSGSSGRRMEILELPEHPYFVGTQFHPEFRSRPTRASPPFVGLVEAAGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7C1</accession>
    <name>U1P7C1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00177</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88036.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88036">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2115436_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="14819" checksum="09845C43F67BAD09" modified="2013-11-13" version="1">MVESSGHPQLSRIYTVYIAMCDSGVSMARTQTQTLIDSQWIGVAFVVGIGLQLVGWIVGIGVFTGLPAYFFVGLVTAWGSPGNTIIEPSIAAFCVAVIGFVLENFLLTVFLVGIPVAITYGVGGVVLALIGAFVGERFLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7L9</accession>
    <name>U1P7L9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00279</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88136">
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        <property type="gene ID" value="J07HX5_00279"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2140122_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="12440" checksum="A2A69C4D95D21D02" modified="2013-11-13" version="1">MLRLEPDELEQLRNAFTPAAPCSPVVYLKWFANDCSDSQAFVDARCRVLIHHLCVLAPPLERPPPERGHVGAVDRHRPGVGLLESEQCPPECCLATARLADNPERFAAIDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7S6</accession>
    <name>U1P7S6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01782</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89612">
        <property type="protein sequence ID" value="ERG89612"/>
        <property type="gene ID" value="J07HX5_01782"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2643516_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8275" checksum="3039C37CDF47763C" modified="2013-11-13" version="1" fragment="single">MTDEFLLLNPGPVPIPDSVRRAMDERMVSHRSAAFETVYERAQDGLATVFEESTLSGVQTATDGTALVLNGTATMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Y1</accession>
    <name>U1P7Y1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00399</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88256">
        <property type="protein sequence ID" value="ERG88256"/>
        <property type="gene ID" value="J07HX5_00399"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_8_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="176" mass="19386" checksum="920A12C221833EDA" modified="2013-11-13" version="1">MSESWRVIESVTEYETGWYDGGYDLLEQPDGSRKRYYWASLPPAVVVVAVADDQLLAVEQYRPTISKYCLELPAGIVEDGESYTTAGARELREETGFAPAGVSLLEEVWVATGVLRHRRGIVFAEGLEPVGVDRDDNEFLSVRAVPTGEAVDRARESPANDATIEALLLAEHAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P827</accession>
    <name>U1P827_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01889</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89717">
        <property type="protein sequence ID" value="ERG89717"/>
        <property type="gene ID" value="J07HX5_01889"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2856973_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="6902" checksum="E4847EBA231BB2FC" modified="2013-11-13" version="1">MAETGNVDRRTNTALNAAVGFVVSWLVARLLSRTRPVRDAVVGAAAFAVVSWIGYERPAVLDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8G2</accession>
    <name>U1P8G2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02009</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89837">
        <property type="protein sequence ID" value="ERG89837"/>
        <property type="gene ID" value="J07HX5_02009"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2189296_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="11036" checksum="E0F52CA34ED2C683" modified="2013-11-13" version="1" fragment="single">MSTDGGSGGATATPDSRAVTVQPGGRCLLGAVIIPVEPNGRSCAAGTEGNDTLMWIAPVLSVLCLPVEIRATTTPRASVNPTPSGTLSFNSSRTTAVGSQPLDRLSTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9E3</accession>
    <name>U1P9E3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00902</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88756">
        <property type="protein sequence ID" value="ERG88756"/>
        <property type="gene ID" value="J07HX5_00902"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544167_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="154" mass="16381" checksum="550848A29F3F28D6" modified="2013-11-13" version="1">MGLSEIAAGIEVTSAQERREVTIIDETDATVTERLAPFAGVLPCEPDAAATAVKRYTAGANVDTAAQAAGLSPITTTKTLHLLGEPVSPVGSADQAVIRDWTNGDCSRHEALKRTQAAETDCMLAAYVETHRPLAEAQRAIEGLLATRRVRRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAH4</accession>
    <name>U1PAH4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease V</fullName>
            <ecNumber evidence="2">3.1.21.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Deoxyinosine 3'endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Deoxyribonuclease V</fullName>
            <shortName evidence="2">DNase V</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nfi</name>
        <name evidence="3" type="ORF">J07HX5_01253</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the endonuclease V family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.7" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89101">
        <property type="protein sequence ID" value="ERG89101"/>
        <property type="gene ID" value="J07HX5_01253"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047631_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043737">
        <property type="term" value="F:deoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00801">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with target DNA" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="237" mass="24920" checksum="D03BB6EC252DBAC3" modified="2013-11-13" version="1">MELERPQLVPDPSLSRAEMKAQQSEIAAIARFEDTGAEAPSLVAGVDQAFDGDTVVSAAVLLQSGSLLERSSARVETDVPYMPGLLSFREGAAALASLTALTRRPELVLVDGSGRIHPREAGLATHIGVALGMPTVGVAKSLLCGRPVSSLADPLATGTRVRIEADDDIAAPDGTTVGYAVQTRQYDAATRHINPVYTSPGHRVSATTAAESVEQTATEYKLPDPIHRADRRAAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAL8</accession>
    <name>U1PAL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01299</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; coenzyme F0 biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89146">
        <property type="protein sequence ID" value="ERG89146"/>
        <property type="gene ID" value="J07HX5_01299"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054174_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00072"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019939">
        <property type="entry name" value="CofG_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03550">
        <property type="entry name" value="F420_cofG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="267" mass="28728" checksum="F9D7377D2D53902D" modified="2013-11-13" version="1" fragment="single">YLCEAAEIAIEEGLLPHSNPGDQTPAQMRQVAALNASMGVMLETTAEIQAHDGPRGKSPGQRLATIQTAGELGVPFTTGILVGIGETWRDRAESLLAIAALHERYGHIQEVLVQPVVENDRWQNGSPSLNTLRRTTAMARAALPEPVSVQVPPNLAPVRKLLDCGVDDLGGVSPVTDDHINPAHAWPAVDELRAIAASGNADLTERLPVYERFLPAAYRSSSFDGRPADPDREWVSAPVREAISADTAAGRRYRSALRNKTPQLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAP0</accession>
    <name>U1PAP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01319</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89166">
        <property type="protein sequence ID" value="ERG89166"/>
        <property type="gene ID" value="J07HX5_01319"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2563533_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9340" checksum="990B32C889B6D44F" modified="2013-11-13" version="1" fragment="single">MWFPLGSRNRVETFSLFGCETECGCDAARPVVESAASLSENNVRGTQPCHEQTQLLWSIRFDASHCDQGGTDREQLHHSTDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBD7</accession>
    <name>U1PBD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01534</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89376">
        <property type="protein sequence ID" value="ERG89376"/>
        <property type="gene ID" value="J07HX5_01534"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_935697_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="309" mass="32967" checksum="C6AEDD62F0BCF178" modified="2013-11-13" version="1">MSRKHSRRAILAGGASAVLGGLAGCLGQGDDSGEGDRQNNTVDTGPGDTGSGSSDPASAQVSFRDWLVAPELTPGVTGNEDRVYRFEYIPGGFLQQAEQDRVQGRASVLDIDPAVIEGRLLQLPAVVYFGEFDQPALETAIESADGYTVTGEYESYRTAENTETGTQFALDEQAVLIGRALEQWIDTQTGTADRLEGTTPVFTQLFDRVPTNLSVTGQLGPPVTFEADLDSLTAWVSATPRLTAGEAVTQRWVYVFDGQPPEDATQAIRQELSDSPLLNSITNTTTDGRFLTVTGELLLPESNSADAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBG4</accession>
    <name>U1PBG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01569</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89411">
        <property type="protein sequence ID" value="ERG89411"/>
        <property type="gene ID" value="J07HX5_01569"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2517608_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="8845" checksum="704FF28C237AB71A" modified="2013-11-13" version="1" fragment="single">MIFVEVPSELLPDDQVTLGTVPRCPHCDDTGTEVGDYDDRFFECSAAPGETCPVMTFVVTNSESAAGAVPTAETDTAACPACGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBN7</accession>
    <name>U1PBN7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01647</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89486">
        <property type="protein sequence ID" value="ERG89486"/>
        <property type="gene ID" value="J07HX5_01647"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025086_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="246"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="503" mass="55415" checksum="681F0C48770E75C7" modified="2013-11-13" version="1">MKLSETQVAVLTTATPNQPQPVDQIATDIDQDPAAVTQAAFELEEEDLVTITADTETTPTLTDEGKRYAADQLPELRLYKIVLATDAEGESVPINDLAPELEAVDIKVALANFARKGYGEIDAGAVRADPDADLAADPEQATLETLAAGDGETDELADPRQLDQLERRGLIDRVETTTRSVQVTDDGVDALMAGVEAADTVGRLTPDLLTSGEFRDVELAEYAVTAEAEATPPGREHVLRQTANRVKDVLTGMGFKEMQGPHVDAQFWINDCLFMPQDHPARTHWDQFDLAEPAVIADLPDALVERVESAHREGAGPDGEGYHSPWGRDVAASLNLRGHTTSLSMRYLAGEAADLEPPERYFSVEKVYRNDTIDPTHLLEFFQIEGWVMADRLSVRDLMGTFEEFYAQFGITDIEFKPHYNPYTEPSFELFGTHPETGELVEVGNSGLFRDEVLRPLGVEADVMAWGLSLERLLMLVYGFDDIRDVHGTLCDLGLLRDVEVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBR2</accession>
    <name>U1PBR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01681</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89516">
        <property type="protein sequence ID" value="ERG89516"/>
        <property type="gene ID" value="J07HX5_01681"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3300654_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4220" checksum="1A0CB85A53A18EA7" modified="2013-11-13" version="1" fragment="single">MPLEPTLHYLCVGMPDNRLVPVIAAGGRSPSTVRTVGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBU9</accession>
    <name>U1PBU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01722</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89556">
        <property type="protein sequence ID" value="ERG89556"/>
        <property type="gene ID" value="J07HX5_01722"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1167943_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="25865" checksum="F46BE10F56552D13" modified="2013-11-13" version="1" fragment="single">MLGESHSGVLEGLARLPTLAHPTVGPGGEEIALYCDTTGRNELHVLDTVTGELKQWSDGEVPRNARWFLRWDTEGDRVYFHLDDAGDEQNDLYALSRDGTVDPVVEMDGQVILNDVSKDGTTLLVGSSRDGQMNIYRHDCPTGETTKLTEYERAAVGATVAPTGDQFAFSTNESDDYENQDVYVADISGSTVRNLKIGETGAEVGPADWGPDVSGYLSTITVRIWVASAFTTCRQTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC12</accession>
    <name>U1PC12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01796</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89626">
        <property type="protein sequence ID" value="ERG89626"/>
        <property type="gene ID" value="J07HX5_01796"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003916">
        <property type="term" value="F:DNA topoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="250" mass="26481" checksum="A946BB371764326E" modified="2013-11-13" version="1">MSRQARGKSAVNLFQLDDDEEIAGVIATDAFDEKAYITTVSQAGYLKRTQASAFQNVNAGGIIAACLDTGDTLADVTITDGQSDLVLATEAGMTIRFDETEARAMGRTARGVRGVDLADSDRVSAVETAPRDRDRALLTVTENGYGKRTPLTEYRPQSRYGKGLVDIETGARNGPVRAATTVDPSDHIVVMSAQGQIMRCPVDEISTVGRNTKGVVVMDLADDDEVASLTVIPGVDTSTDADADTESDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC32</accession>
    <name>U1PC32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01817</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89646">
        <property type="protein sequence ID" value="ERG89646"/>
        <property type="gene ID" value="J07HX5_01817"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3038917_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="54" mass="6643" checksum="AB00C26E2F02C595" modified="2013-11-13" version="1">MLRACDRKLQIYAWRAEREWKERYESDYDIEITCEEMRNAAEYVDRDIAVPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC87</accession>
    <name>U1PC87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01878</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89706">
        <property type="protein sequence ID" value="ERG89706"/>
        <property type="gene ID" value="J07HX5_01878"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1187118_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="24012" checksum="88B49A8A2C8E518B" modified="2013-11-13" version="1" fragment="single">MSLSWPRIITGAAIMSKQTVDLALIGWAVGSTAVAGLAYAYAYWTLAKFVGIGLAGGTVALVSQSYGGDEHGRASLIVKQGVWVALAIVIPVVGCYLAFAEPLIAVLGSNPGPIGYGATYLFVVAPALAFEYLILLMSRTYAGVGDTFTPMVVRAGGGLLNIVASVGLVLAGLGVTGVALGTLLSTGATLVVLGWGCLGRSYPVSWMQSSPVAVELSEPQLDHKLGTQLVTVSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCA6</accession>
    <name>U1PCA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01893</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89721">
        <property type="protein sequence ID" value="ERG89721"/>
        <property type="gene ID" value="J07HX5_01893"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1258402_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RHH_1" evidence="5">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DZANK-type" evidence="6">
        <location>
            <begin position="165"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="219" mass="24340" checksum="A4623335FC0B8E7A" modified="2013-11-13" version="1" fragment="single">IRYHDRHLSDTQGRLIYPGKQPIKQLMSKITFRADDDLVARLEEFDASKSEVMRQALRQYLSAHSEAPDRTEDNKSIDELIANRIDERLDRQLESAFTPRQPQDINVNIALDGESATASDTTTTAANAERTASHTASAEPSHESPGRKTETVPPDDADANERKTCTQCGKDLPSSHVYCPNCGEKSSRRAFCECGDELRSDWAFCPGCGRRTPAADVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCJ3</accession>
    <name>U1PCJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01983</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89811">
        <property type="protein sequence ID" value="ERG89811"/>
        <property type="gene ID" value="J07HX5_01983"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_7_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="458" mass="47385" checksum="0CD5261997D5133C" modified="2013-11-13" version="1">MSQGGTADKNRWLIAASAVLIHLSIGSIYAYSVYQAPLQALHGWSNSQVTLAFSTGLLVLGLTAATMGWFVEKHGPRRSGLIAAGVFAAGTIGAGVSVRIGSLPLFIGTFGVLGGVGLGIGYIAPVSTLVAWFPDKRGLATGMAVMGFGGGALITGPAAQFLMTTLSSASDKTFADVLVLDDGTKLDVFASVTSVSQTFYLLGAGYFVAIVLGSLYLGKPPADWQPEGTGEVQTQSDGVTAGARAEDIAQLTGREALHTPRFYLLWITMYLSISAGLMLLSQAANMTSEITGASASVAATVVGAIGVFNAGGRIGWAALSDYIGRTNMFTFFLGIQAVALVVMPLISNVWLFAGFLFLIVSCMGGSFACLPAYIADLFGTKEVAVIHGYTLTAWAVAGLISPQLIAYIRDTTGGYTGAMYLIAAALVVGVVVLTGLRVRIRKLQTENAAGTSPAATDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCK6</accession>
    <name>U1PCK6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Protein transport protein Sec61 gamma subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secE</name>
        <name evidence="10" type="ORF">J07HX5_01993</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89821">
        <property type="protein sequence ID" value="ERG89821"/>
        <property type="gene ID" value="J07HX5_01993"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_191921_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
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    </dbReference>
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        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
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        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
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    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6027" checksum="C3143B2E240251E3" modified="2013-11-13" version="1">MNTPTDLSSYIRVLKLASTPSWEEFKQVAKIAGAGILLVGTIGFLMFAFMFFLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCP6</accession>
    <name>U1PCP6_9EURY</name>
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        <submittedName>
            <fullName evidence="6">Topoisomerase IA</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">J07HX5_02023</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89851.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
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        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
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        <property type="entry name" value="PTHR11390"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF56712"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOP1Ac" evidence="5">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="452"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="497" mass="55006" checksum="7209D8358A9825E3" modified="2013-11-13" version="1" fragment="single">YPDDLDPAALVAAFTGSAFDDAATQLLELDELNPTRGDEATTDHPPIHPTGELPDRGELSEDEWEIYTLIVRRFFATVAEPATWKRLRVVATVGNDRLKANGRRLTSEGYYAVYPYPSTTETQLPALAEGDQLEIVETQIDAKETQPPRRYGQSRLIETMADRGLGTKATRHRTIEKLYDRGYIESDPPRPTALAEAVVEAAEQFADRVVSEEMTAQLEADMTAIAQGEATLEAVTDRSREMLREVFAELRASREAIGEQLQESLKDDRRLGPCPESEHDLLVRQSGDGSYFVGCDGFPDCQFTLPLPSRGEPLVLAESCDDHELNHVKMLAGRETFIHGCPRCAAAAADDTEDEPIGPCPDCGASEDGSLAVKRLRSGSRMAGCTRYPACEYSLPLPRDGQLTVTDTICDEHTLPELVIDADADDPWELGCPVCNYQAYKSQSDTEQHANQNATENKKKDRNKDENKESTNATADDEKLEQTEEEMRQLESQSATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFT1</accession>
    <name>U1MFT1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00160</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88019">
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        <property type="gene ID" value="J07HX5_00160"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954574_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14613" checksum="26D92BFB595EA5DD" modified="2013-11-13" version="1">MPEIALTETQHRRLEAVREDVEAAFVDNYGRVPIEDAIEYLLDTYTPPGEDGAADAYEHVATAEYPQLQRVAXXXXXXXIVQPRQCSQMRPSEDTDTLVERDPARQDTRDQCLRRRQTFRGTEAPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFV7</accession>
    <name>U1MFV7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-binding protein Mrp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00195</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88054">
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        <property type="gene ID" value="J07HX5_00195"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_6_1_2"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="16915" checksum="A031250C06AD64BD" modified="2013-11-13" version="1">MVHKVLTQLVEDVQWGPLDYLVVDLPPGTGDTQLSVLQTLPVAGAVITTTPQAVAVDDGRKALQMFAKHDTPILGVVENMTAFQCPDCGSTHELFGAGGGQTLAREGDLPLLGTLPLDPAVRTATKPAVLADGPPPTGSGRLSGLPPICRALCTVSESPRDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG41</accession>
    <name>U1MG41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00307</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88164">
        <property type="protein sequence ID" value="ERG88164"/>
        <property type="gene ID" value="J07HX5_00307"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090236_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="53"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="21412" checksum="ED4A0D4875A374F7" modified="2013-11-13" version="1">MIIRASTVSPIVPGDIRQFELFAPVYDLVMPSADPAALRAALKTATRPLVRLLDVGGGTGRGARAVELPSRIVVDPAERMLQRAREKELSTVRADGSRLPVADGAVDAVLITDALHHIRDQHGVVHEAHRVLAPGGVLVVQEFDPTTVLGRLLAGGERLVGFDSTFRSPPALRDIIARIGFDTSVVETGFEYLVAGVCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG72</accession>
    <name>U1MG72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type Fe3+ transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00347</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88204">
        <property type="protein sequence ID" value="ERG88204"/>
        <property type="gene ID" value="J07HX5_00347"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021838_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="57"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="340"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="539" mass="57805" checksum="5CFDBBA08A924B2A" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGG9</accession>
    <name>U1MGG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00453</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88309">
        <property type="protein sequence ID" value="ERG88309"/>
        <property type="gene ID" value="J07HX5_00453"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103619_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="SSF143870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="162" mass="17289" checksum="09CAAED2B1FC180D" modified="2013-11-13" version="1">MKLVEGTTTVQQVDRALSQLAEIGETHGTVVQAFDARYVVDRHHLTLATDLARRARERSVAIARDPAMEIMLYAAGRRQISRALEMGIAVGEQSVAVVVTGGDETGAAAAVGEWLSPADTVGAYDPERVCSFFDITETALAATTGGIAELVHERVALLVVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHE7</accession>
    <name>U1MHE7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:ubiquinone oxidoreductase 49 kD subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00885</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88739">
        <property type="protein sequence ID" value="ERG88739"/>
        <property type="gene ID" value="J07HX5_00885"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="5">
        <location>
            <begin position="39"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="6">
        <location>
            <begin position="301"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="551" mass="61618" checksum="F724A72EF5BA6CA1" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHF2</accession>
    <name>U1MHF2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00890</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88744">
        <property type="protein sequence ID" value="ERG88744"/>
        <property type="gene ID" value="J07HX5_00890"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3208913_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="46" mass="4778" checksum="25D2E3672A0BD03C" modified="2013-11-13" version="1" fragment="single">MVAGVGATGKLLQTSDTHILFENPENQVTGRDISGLVGSVKARGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHG0</accession>
    <name>U1MHG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00900</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88754">
        <property type="protein sequence ID" value="ERG88754"/>
        <property type="gene ID" value="J07HX5_00900"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_3_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="103"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="208" mass="23481" checksum="D196A3A08CAAAF23" modified="2013-11-13" version="1">MDGYLAVTSTGAFIGNADLLNHKRREYERRRGRLQQQGTRSVHLTIQSIGDTFANWSENFLHQASKRLVEEAVSQGCSVIVFEDLEQIRERISNASKFQQWAFRELKRQTTYKARSEGITVESVHPAYTSQRCSHADCGFTHEDNRDGDDFACQKCGKELYADYNASRNIAHRYVQNRLKSGAGRATNHLALKSGTLNGNGDYTPSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHH9</accession>
    <name>U1MHH9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peripla_BP_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00920</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88774">
        <property type="protein sequence ID" value="ERG88774"/>
        <property type="gene ID" value="J07HX5_00920"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_6" evidence="1">
        <location>
            <begin position="49"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="435" mass="46316" checksum="A2D71C0E5892BD2C" modified="2013-11-13" version="1">MRDGSDNTGSKGNGRRSFLTRVGGLTAAGTSIAAAGCVGGFLGSDSEGILVPGLYDISGATSDVGRPTGIGSRDAIAWLNENENVSETLGTSEGIAHEWIDYAYEVPQAQSHYDEYAPQDPPLFIGWGTADTEALSTSVASDEIVYISASYSDNLLAEETEYNFFTNMDYTSQARAHLKWINENDSGSTAAMIRNGSAFGTTPVAGAYAYGQELGGVEMAFGSDGSGAGGIELALGASSAATQVTRAQNNGVDYLIHQNVGSPNRVLLNAIDDAGADITVMGMTWTVDAGKIADAPEVHEGMRYVNSNKSFSEVESEEPAGWDIIQDSFEREGRDFEDGSVANANYVRGVVHALLAYEGMRAADDPRSGPAVRDAIIGLEDFDARGLLIDTVNFQEGDRRPTMTGRTYVVEDGSLVPDGDIELERRESWLPPFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHI8</accession>
    <name>U1MHI8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00930</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88784">
        <property type="protein sequence ID" value="ERG88784"/>
        <property type="gene ID" value="J07HX5_00930"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629558_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8458" checksum="3C3C5AB2C7A8FA39" modified="2013-11-13" version="1">MSVTVFLESAMDGDHEIECADATIVRDVVRLTPRDERRDRVVPLDNVTGIAGDSVTNEIEEIEFPGGRATELVTQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHV8</accession>
    <name>U1MHV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01055</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88909">
        <property type="protein sequence ID" value="ERG88909"/>
        <property type="gene ID" value="J07HX5_01055"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_945324_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="254" mass="27108" checksum="12DFE0EE212CD583" modified="2013-11-13" version="1" fragment="single">MIERLRQPAYTGENRCLPCTVINTLLPLGLSGASAVAGATVSPLVAVVVGGGVLAVAMEAIWLRGYLVPGTPTLTKRYLPPWVLAWFGKGPAAGEPAARTVPSSADKEDYEARLQETGVIGPCEDKDDICLTASAHAAWRHQITRSPDEPSPDQVAAVLDLDLSAGQLEQSGDAHVLRDGDETIAAWPSETAVRSDLATAGVLDDRLDWESLTTHQRLTYLHTVRLFLEECPDGSPARLESETVESCCSSHDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHY1</accession>
    <name>U1MHY1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01086</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88939">
        <property type="protein sequence ID" value="ERG88939"/>
        <property type="gene ID" value="J07HX5_01086"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675303_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="1"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="407" mass="44226" checksum="D4A1516D7363C280" modified="2013-11-13" version="1" fragment="single">TVETAARRYGFREIGTPRIEPTGLYADKSGAEILEELYTFEDKGGRQIALTPELTPTVARMVVDRQQALTKPIKWVSTRPFWRYEQVQQGRFREFYQTNIDVFGSSEPAADAEVLAVAADALTDLGLTAADFEFRVSHRDLLDGLLEAFDGTVDTAAAIRAIDKRAKIAPDEYAALLRAAGLADRQVSQLDELLATPADRLEELTAFADVDDAVGNLTAVLEAAAERGIREYCTLSLTTARGLDYYTGVVFECFDSTGEVGRSVFGGGRYDDLIESYGGQPTPAVGVAPGHATLALLCQRAGVWPDERLTTDYYVLQVGETGETAATVARQLRNRGHVVETDVSGRSFGAQLEYADSINAETVVIVGERDLAEGKLTLKQMASGEQQQVPVEAFPGDHSRPTVADFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHZ9</accession>
    <name>U1MHZ9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01114</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88964">
        <property type="protein sequence ID" value="ERG88964"/>
        <property type="gene ID" value="J07HX5_01114"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033621_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="84"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="352" mass="37498" checksum="0BF6751116908B03" modified="2013-11-13" version="1">MSQEDASEPPSLTRPKFILRKERLYRRLFAGCAVLTIAMTAGIILSLSGQALIFFETVSPVEFLTGQDWSPLSNEPSYGVLPLISGTLIVTAGAAVVALPVGLGAAVYLSEYASPRVRSVVKPVLEILAGIPTVVYGYFALVYLTPLLDAPLPIKQTIIPESLGFSLPVIPGWVPLLPEFTLVVEKFLLVVPSVGTFNALSASIAVGIMIIPMVSSISEDALSAVPDSLREAAYGLGSTKFDVSTKVVVPAATSGIVSSYVLALSRAIGETMIVVLAAGKSPRIPTVPNILENFTESIETMTVAMVNIASAESLGQTVTYESMFAIGLTLFGITLTMNYVAELISRRYREEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI52</accession>
    <name>U1MI52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01190</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89039">
        <property type="protein sequence ID" value="ERG89039"/>
        <property type="gene ID" value="J07HX5_01190"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1006863_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="29515" checksum="6F1D478F6D356E0F" modified="2013-11-13" version="1">MAGTQIRVGWRASLDLTGRVLVYLAGPLAAPLVLALYYSESLTPFLVAIAATVGLGVGLLRIGDRDIDLGAREAFLAVSLIWLLTAAVGAIPFVVADVGVFSVTDYGPVGALHALFEAMSGLTTTGATVLEEFSIHSKSIMMWRQIIQWLGGLGILILATAVLSSLGVGGAQLMESEKQTDNVDKLTPRISETARLIWGLYVGITALAAVTYFTLGXXXXXXXCGQTRRVMRFHHCPKRRSPITPKTHENTNELTPQQAAVDAGHVVKLSSFQAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI82</accession>
    <name>U1MI82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01231</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89079">
        <property type="protein sequence ID" value="ERG89079"/>
        <property type="gene ID" value="J07HX5_01231"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1207582_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="23778" checksum="066CA8171C4B5748" modified="2013-11-13" version="1">MAYFTSMTVDTAIDTVAQEIQGTVIFLADRLPDLLLAAIVVFAAFRIVDQLEPYVYSVANAMDESVTGELTTDLLPDQGLAPVAFGAVKALLVLYGGLIATRIIGFSVLERELDRIVFYLPDLFGGLLILLVTLAVARVAGRRVAGGELSSELGYATEVALASKVVIVLVGVPVGLEMIGADLQLVYLLADGFAGSVGIGLTAAIAIVVGVVAGVALRDSTLFGGTSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIC3</accession>
    <name>U1MIC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetyl/propionyl-CoA carboxylase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01287</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89134">
        <property type="protein sequence ID" value="ERG89134"/>
        <property type="gene ID" value="J07HX5_01287"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1168546_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0092">Biotin</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="162"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="237" mass="25568" checksum="CD3A9144BBAC43E7" modified="2013-11-13" version="1">MDDALRQGDQLVTDYDSMIAKLLVHGPDRETAIARGRRALNEFELEGVVTIVPFHQLMLTDDRFITGRHTTKYLDDRLEHDRIEQAYERRSGAAAATESGENDEDVTEREFTVEVDSKRFEVLLEERGTAPRPAASGDNNDGGNSGSGGRSRRSRSEGSGGDSTSGDQTEVTAEMQGTILEVPVKEGESVAAGDVLCVLEAMKMENDVVADAGGTVADVAVDAGESVDMGDRLFLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIM6</accession>
    <name>U1MIM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01426</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89269">
        <property type="protein sequence ID" value="ERG89269"/>
        <property type="gene ID" value="J07HX5_01426"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075260_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5879" checksum="714624561DE3F380" modified="2013-11-13" version="1">MCRYCAYSYHDGWTALLEYDDTYQQVTSQTTATHGFHQEWDELREEISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIY6</accession>
    <name>U1MIY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01542</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89384">
        <property type="protein sequence ID" value="ERG89384"/>
        <property type="gene ID" value="J07HX5_01542"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2534535_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9232" checksum="1A917C7AE928A224" modified="2013-11-13" version="1">MMGVEPFEVTPDALDDSWFRRNLHSRAGRAILDISPGGLVMEPRERRHSLVGERSSEFGSGELGSSLVSNPGECVRRVWSKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJJ7</accession>
    <name>U1MJJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01830</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89659">
        <property type="protein sequence ID" value="ERG89659"/>
        <property type="gene ID" value="J07HX5_01830"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172273_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8948" checksum="0DE753A13D7AABB6" modified="2013-11-13" version="1">MSMTAGRSDPALSEKQRRILEYLREHRTSTTYFKSRLIADDLDLSSKEVGANMHTVAEAAEFSVEKWGYSSGTTWMVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJL5</accession>
    <name>U1MJL5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF302 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01851</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89679">
        <property type="protein sequence ID" value="ERG89679"/>
        <property type="gene ID" value="J07HX5_01851"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1718168_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005180">
        <property type="entry name" value="DUF302"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03625">
        <property type="entry name" value="DUF302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="SSF103247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF302" evidence="1">
        <location>
            <begin position="52"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="16641" checksum="1ABE7BD5C80CC356" modified="2013-11-13" version="1">MSSQTAPTAEEAMHTTLEMSFEDAVPFVQLEHELADFETVTVSRLDQMIEGMLGETVEQTALIVVCHPEIARDALAIDHQLGGMLPCTTVVYERPNADDRVHVHHFSVTKAIRDLGCQPADNDEEIQELVEFTGEQMQTVWDNIEAHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJL8</accession>
    <name>U1MJL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01856</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89684">
        <property type="protein sequence ID" value="ERG89684"/>
        <property type="gene ID" value="J07HX5_01856"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="324" mass="34529" checksum="4F191F2D613AA85A" modified="2013-11-13" version="1" fragment="single">MVDLRSDTVTLPSDEMRTAARDAAVGDDVYHDDPTVNELQRRAAAVLGMEAALFVPSGTMGNQIAIRTHTERGQELLCGVESHVYKWELGGIVQHSQVQPRTIDAGDRGVITPEQVRAGYIEESLHEAGTGLLTLENTHNSRGGRAIAVDRIAAAAETAHELGLSVHLDGARLFNAATALGVDAAEIVEPVDTVVACLSKGLGAPVGSILAGPEETIAAARRTRKLFGGGMRQAGMIAAPGLRALENRHRLSEDHRRAERLAAGLDGIDGVSIEPPETNIVIAETDRPAAAFLEDCKAEGVRGVQFGEQTVRFCTHWDVDDDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJN8</accession>
    <name>U1MJN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01881</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89709">
        <property type="protein sequence ID" value="ERG89709"/>
        <property type="gene ID" value="J07HX5_01881"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1182272_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="4">
        <location>
            <begin position="195"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="26383" checksum="CB693F8CF8729C73" modified="2013-11-13" version="1" fragment="single">MRARHRSSGSVIGLHDRSVHASGTTVLKEAVERSAPALIVLTLYSCVVHACSRLPGRTTTAPTRPRQLPRDPTERPSRACYTAVRRTRLLCPGDCVPPDPRQEKTRERQDTQHEQQYRCEDDNRAERADNDTDLYEFVQSSLTIEFPATVVNGWYEFTRTGTREELDWFQAALNEQSRAYELRSLVRTTETDGLLTDRQCEILEAAAQAGCFEVPRQSTLADVAAGLDVDKSTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJU6</accession>
    <name>U1MJU6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Spt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spt4</name>
        <name evidence="4" type="ORF">J07HX5_01946</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer composed of Spt4 and Spt5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal Spt4 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89774">
        <property type="protein sequence ID" value="ERG89774"/>
        <property type="gene ID" value="J07HX5_01946"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199467_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00949">
        <property type="entry name" value="Spt4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007178">
        <property type="entry name" value="Spt4_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038589">
        <property type="entry name" value="Spt4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40704">
        <property type="entry name" value="PTHR40704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Spt4" evidence="3">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="7090" checksum="6B4DFB6C5F6269D3" modified="2013-11-13" version="1">MADRLACRECHRVQSNEEAEACEACGSTSLTEDWAGYVIIAHPADSEIAVEMEATDSGKYALKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJU9</accession>
    <name>U1MJU9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HisKA_7TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01951</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89779">
        <property type="protein sequence ID" value="ERG89779"/>
        <property type="gene ID" value="J07HX5_01951"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_822576_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_7TM" evidence="2">
        <location>
            <begin position="20"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="338" mass="36376" checksum="92A8F3357096B594" modified="2013-11-13" version="1" fragment="single">MLVSLQTTAAFASYLAVFSLAGIASLAAAVRASRIDNAEIRAGLVWLLLTTGAWGLLQAGLFATSGPVRRFAYTAGLVVGFATVGAWLYFVSAYTNRGYHRNARVRRAAVVVFLVVSAAKVTNGLGLHTLYFTTKQSTTPFAHLAIEFGPLHWLVTGLSYSLATTALFALLDMYVRAGYDTRPVWVLTVVVGLPATLDVLGAILPGVVDASYAPIGITAFGVFALYVYEQRFVTAPETDGDAAVFLDVDNKVRDYTAAAGRLFSGLAGARGRPLSAVLPQVAKAADNETVVGRQVDDEDRYYMVSETSVELGEAEQRVLILSDVTVTERRRRELARHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJW8</accession>
    <name>U1MJW8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutaminyl-tRNA synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="3">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01971</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89799">
        <property type="protein sequence ID" value="ERG89799"/>
        <property type="gene ID" value="J07HX5_01971"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_730573_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="9">
        <location>
            <begin position="2"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="378" mass="38877" checksum="048A39380C81D13D" modified="2013-11-13" version="1" fragment="single">ADYVPPYSATVVERLTAAGATIPGKTNMDEFGMGTTTETSAFGATENPAAPGRVPGGSSGGSAAVVAAGDADMALGSDTGGSVRCPAAFCGVVGLKPTYGLVSRYGLVAYANSLEQIGPIAPTVADAARLLDVIAGPDPNDPTTREAGAKGEYASAADGDVAGLTVGVPTALLDGAAAEVVEQFWATIDELEARGASHHEVALPSLEHAVEAYYVIAMSEASSNLARFDGVRYGPATEQPGNWNETFAAVRETGFGEEVKRRVLLGTYALSAGYQEQYYKKAQDARAWIKQDFDDALTEADVLASPTMPVAPFERGTSLSDPLQMYLADANTVPVNLANLPAISVPAGETDDGLPVGIQLIGPAFGEETIIRASSALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK36</accession>
    <name>U1MK36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02061</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89889">
        <property type="protein sequence ID" value="ERG89889"/>
        <property type="gene ID" value="J07HX5_02061"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181982_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="10826" checksum="ACBECD272CD276C2" modified="2013-11-13" version="1">MSSHSDSETETVTVSLTTNDTTETVTVSRAMIELLREDDETAPGVIGDMAVLSLAQQAHGIVHHSDGEVPEQIAAAEDHTMALFEERFGQSYAEMTGHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK73</accession>
    <name>U1MK73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoglycerate dehydrogenase related dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_02122</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89949">
        <property type="protein sequence ID" value="ERG89949"/>
        <property type="gene ID" value="J07HX5_02122"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="69"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="110"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="313" mass="33154" checksum="5AC37CBEE36F40DF" modified="2013-11-13" version="1">MRILVLRGDVHGMDTPAYASAIRDRLPEADVEVAVTPADERSGVRSARVVTGHAPPPQIFETDGATPELFACLYAGTDHLDLDALAAADIAVTNAAGVHGPNIAEYVLGGILAHAQGFLQARSQQRTREWRSYQTSELSGATVAVVGLGAIGQAVADRLAAFDAETVGVRYTPEKGGPTDTVYGFDEIHAAVADTEYVVLACPLTEATEAIVDAELFETMAPRAVVVNVARGGVVDTDALVAALRWNSIGGAVLDVTDPEPLPADHPLWRLDNVLITPHNAGHTPAYYERRADILTANVAALEQGDPLQNRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV07</accession>
    <name>U1MV07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00041</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87900">
        <property type="protein sequence ID" value="ERG87900"/>
        <property type="gene ID" value="J07HX5_00041"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3263656_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4642" checksum="3D98BEA0CF5F17B4" modified="2013-11-13" version="1">MHTERPALGEMLEDFVKLGSIEFRSEPLNAASREQTRPQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV48</accession>
    <name>U1MV48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00096</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87955">
        <property type="protein sequence ID" value="ERG87955"/>
        <property type="gene ID" value="J07HX5_00096"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629556_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8820" checksum="4674A972C87799A8" modified="2013-11-13" version="1">MLKREGHKDEWQKRPWYQGTAGAVEGDDEYQASEFAASEADSPEHKTESGPKRNDVEIALRLLRATDRQPMGERYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVD4</accession>
    <name>U1MVD4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00059</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ERG87918">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18579" checksum="C911AE706FAA5DED" modified="2013-11-13" version="1">MSTVSATLHTSEGPIEIELFDERAPTTVENFVGLATGDTSWEDPESGDQRDGPLYDDLLFHRVIDDFMIQTGDPTGTGRGGPGYTFDDEFHSELRHDGPGTVSMANRGPDTNGSQFFITLAAQSHLDDKHAVFGEVTNGMDIVEAIGAVPTDGNDKPQTPVQLDRVEIERE</sequence>
</entry>
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    <accession>U1MVD8</accession>
    <name>U1MVD8_9EURY</name>
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        </submittedName>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="3">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="8"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6925" checksum="6338C533CA38D198" modified="2013-11-13" version="1" fragment="single">MLHSYYLINVMTRPSRQRERERERESETEADSTQTGTQTCPECSSDNIVTDADRGELVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVH6</accession>
    <name>U1MVH6_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG87968.1"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="501"/>
        </location>
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            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="507" mass="56025" checksum="3CAD1CC5011047A5" modified="2013-11-13" version="1">MGSDREAGGQVPERVERVEIITRRLADCDNPTEVCWTVTESIDGIFSFDAAVTYAHENGQLHPVATIADELYPAAHQGADHGIAGAVLQSGESRITDDLAGEPAPKEHDGFRSALTVPINDERGLQLLSTSPKMFSETDRRYARLICRQAASALNRIAAEHQVQRERDEFTTLFENIADPILRYKIQNDMPVVDEVNSALIQQFMITADAVTETPLNNLPGQLEQTPPEWTAARQGEQVEQRLERQTVDGVRQFLMRTVPGTPDNPLQAGTGYVIYTDVEESRRREQMEVLNRFLRHNVRNDVSVMHGHLDRVIETVDDPAIIDHVTATLRASNRIERRGQKARKAQQLIGKTVDQNPTRFNLVDIVTERADVIRQSFPEVTIDIHCRNRTVEVKTDSSLPLAIDELFENGAAHGGPDPSIEATITATGSTAELAIADDGPGIPDRETRVIERGEETQLNHGRGIGLWLVAWIVDASNGDLSFSTPDDGGSVVSLSLPRPPDPSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVS2</accession>
    <name>U1MVS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00358</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88215">
        <property type="protein sequence ID" value="ERG88215"/>
        <property type="gene ID" value="J07HX5_00358"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1922703_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="131" mass="13492" checksum="BEFC7D4040B456FF" modified="2013-11-13" version="1">MKRGRILLLALALLAVTAGGTHGATSMTLDRTANIDIVDQNAGLLAVSQTTTGYNSTLNTADLTVEVTNQISVSIDQVDISAGGTAKPTGSLSPGVSDSVSFPDVDCNGTIAIAYEIGSLNQRIERPITCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW8</accession>
    <name>U1MVW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00266</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88123">
        <property type="protein sequence ID" value="ERG88123"/>
        <property type="gene ID" value="J07HX5_00266"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2140121_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="10750" checksum="B9BE3670DD4430E4" modified="2013-11-13" version="1">MISGVSDGTACSVTAAGPVPSAWGSGVQADYPFSCATCPPSGCPGVTQALAVAKLAAPGQTKLTQIELAGVVSGWNGSSASRASLEAVHAVSAPASPSSVSLNPARSPAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW9</accession>
    <name>U1MVW9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Replication factor C small subunit</fullName>
            <shortName evidence="6">RFC small subunit</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Clamp loader small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rfcS</name>
        <name evidence="8" type="ORF">J07HX5_00408</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the activator 1 small subunits family. RfcS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88265">
        <property type="protein sequence ID" value="ERG88265"/>
        <property type="gene ID" value="J07HX5_00408"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01509">
        <property type="entry name" value="RfcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023748">
        <property type="entry name" value="Rep_factor-C_ssu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="86"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="94"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="364" mass="40115" checksum="405D50C0C8D1FD72" modified="2013-11-13" version="1">MAGLDFGVRENERVGMWGSDRVEQSRIEQNSLSAIHRYFSMSKGDTGSTTAREKVWLEQYRPQTLAEVAGHDAIIERLQTYVKQNDLSHMLFAGPAGVGKTTSALAIARELYGEDWEQQFLELNASDERGIDVIRERVKSFARTAFGGVNYRIIFLDEADALTSDAQAALRRTMEQFSDNVRFILSCNYSSQIIDPIQSRTTVFRFAPLSDEAITQQVQEVADAEAIELTEDGLEALTYVAGGDMRAAINGLQAAATAGTVDEDAVFAITSTARPEDIEAMVTRALDGDFTAARSQLDRLVTEEGIAGGDIIDQLHRSVWEFDLDDAAAVRTLDRIGEADYRITVGANERIQLEALLASLALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWE3</accession>
    <name>U1MWE3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00580</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88435">
        <property type="protein sequence ID" value="ERG88435"/>
        <property type="gene ID" value="J07HX5_00580"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2946823_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6601" checksum="8674F1474CCCA203" modified="2013-11-13" version="1" fragment="single">TGSAKQNGHTLEGLEFDDETREMLGLDDIEQILGELNLEEDTEISEIEDAEEIPDPEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWH5</accession>
    <name>U1MWH5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00620</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88475">
        <property type="protein sequence ID" value="ERG88475"/>
        <property type="gene ID" value="J07HX5_00620"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2473949_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012441">
        <property type="entry name" value="DUF1643"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07799">
        <property type="entry name" value="DUF1643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="9725" checksum="7E3245BB638EF6EF" modified="2013-11-13" version="1" fragment="single">MTDRQSNTPADGAAFVDAGATTDETDTYRYRLWRSWDQTAPMLGFVMCNPSTADATSLDPTCRRCVGYAREWGYGSVEIGNLFALRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWN6</accession>
    <name>U1MWN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00522</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88378">
        <property type="protein sequence ID" value="ERG88378"/>
        <property type="gene ID" value="J07HX5_00522"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2595141_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8336" checksum="9A737ACED5D4683D" modified="2013-11-13" version="1" fragment="single">RMRRIHIHPGKIGCMCRDCIDTAPFSGTDATSRDGSSSITGPRPTDAARDPNATWTGVVAAVVTRLAAVDRKSANGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWQ2</accession>
    <name>U1MWQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone, small heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00726</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88580">
        <property type="protein sequence ID" value="ERG88580"/>
        <property type="gene ID" value="J07HX5_00726"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_9_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12712" checksum="4FC2696709D3CDAD" modified="2013-11-13" version="1">MSELRAAVGDLPEAVFADVLESEEAYLVVLDLPGATAETVDVRVEDGRLVIEARREKAIPPAFRYVNEGRSLFLDVELPLPADTAGHAAEADLAHGVLELRLPKQADAAETNIPIDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX04</accession>
    <name>U1MX04_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00659</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88513">
        <property type="protein sequence ID" value="ERG88513"/>
        <property type="gene ID" value="J07HX5_00659"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_7" evidence="6">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="169" mass="19834" checksum="DFFDEDFF0ED1D7EB" modified="2013-11-13" version="1" fragment="single">EWHEDTEGLQAWKDGKTGYPIVDAGMRQLREEAYMHNRLRMIVASFLTKDLLVDWREGYHWFRDKLVDHNIANNNGGWQWAASTGTDAQPYFRVFNPMTQGERYDPDATYITRYVPELRGVDPEVIHGWHDASLTQRRRAAPEYPDPIVDHSERREQAIAMFERARGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX06</accession>
    <name>U1MX06_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps10</name>
        <name evidence="6" type="ORF">J07HX5_00826</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88680">
        <property type="protein sequence ID" value="ERG88680"/>
        <property type="gene ID" value="J07HX5_00826"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153624_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="6"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11951" checksum="4721D7F3FC1AA964" modified="2013-11-13" version="1">MPFVTRLTLESGDSDLLESVVADIKRQAERKGVELKGPHPEPPQQLTVAQHKRIAAEGTFDPWTYTIYARIIEIIGHGGFARSLAERAYPDRIHVRADVEQLTQTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX21</accession>
    <name>U1MX21_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA mutase N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00674</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88528">
        <property type="protein sequence ID" value="ERG88528"/>
        <property type="gene ID" value="J07HX5_00674"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="1">
        <location>
            <begin position="42"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="559" mass="61918" checksum="F1FF4A7D8205BFE8" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX73</accession>
    <name>U1MX73_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00891</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88745">
        <property type="protein sequence ID" value="ERG88745"/>
        <property type="gene ID" value="J07HX5_00891"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107890_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="15908" checksum="76D421A133ED3F3C" modified="2013-11-13" version="1" fragment="single">MSNSVSTEKQRLVAVAGIPGAGKSTVAALIVDRIGADHLRTDEIRKELFDEPAYTDTETNTVYQTIHDRADTCLAGGGSVVLDATFAVEADRHAVHNLAADHGVGFQMVKVTCDPSVVTDRIGERDGISDADLAVSHEFRSRLSRSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXK7</accession>
    <name>U1MXK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01006</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88860">
        <property type="protein sequence ID" value="ERG88860"/>
        <property type="gene ID" value="J07HX5_01006"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2283159_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="10776" checksum="44600D3D648F1CF8" modified="2013-11-13" version="1" fragment="single">MHVGIVGAGAAGAAAAYTLETVVPDIELTVLEKSGGVCGRAAARRHGDVTYDYGANYLKDDDERVVELVTEELSTAGLVDITAPIYVFDSDGTVSEGRDADDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXM4</accession>
    <name>U1MXM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00904</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88758">
        <property type="protein sequence ID" value="ERG88758"/>
        <property type="gene ID" value="J07HX5_00904"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027052_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007408">
        <property type="entry name" value="DUF460"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40707">
        <property type="entry name" value="PTHR40707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04312">
        <property type="entry name" value="DUF460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="657" mass="73469" checksum="42500353672B60E7" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXN5</accession>
    <name>U1MXN5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Quinolinate synthase</fullName>
            <ecNumber evidence="3">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01041</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88895">
        <property type="protein sequence ID" value="ERG88895"/>
        <property type="gene ID" value="J07HX5_01041"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047382_2_0_2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="332" mass="36217" checksum="C6A75A62FF3D96E8" modified="2013-11-13" version="1" fragment="single">MPRLETADIETDLSLFKYDNLAQLPPAYRTLDRAERTNRIEAALATLGEDVVVLAHNYQRAEIVDHADFVGDSYGLSTEAAATDAPYVIFCGVTFMAESADIITDDDQTVILPSMEASCPMAGMAEALQVDSAWTALTDATDDTVVPVTYMNSYADLKAFCAEHGGAVCTSSNAHEVFEWAFERGDTVLFLPDKYLGRNTAHRLGLEDAIAEWDPWDTAGTDAAEVATADVILWDGYCQVHERFREHHVTALREAHPTANVVVHPECRRAVVEAADVVGSTATIRETIANASAGETWAIGTEIHLANHLDRWYPDVEVLALCGDACMDCNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXX5</accession>
    <name>U1MXX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Divalent cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01155</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89005">
        <property type="protein sequence ID" value="ERG89005"/>
        <property type="gene ID" value="J07HX5_01155"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111003_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="PTHR16228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="MgtE" evidence="7">
        <location>
            <begin position="57"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="19955" checksum="BDB10C452968944A" modified="2013-11-13" version="1">METAQGAVSLGSWRWQSIVTTMFPLLVVLSCVVLVAGVTLEQAEGLLTEYGVLAVMVPTMIDTGGNLGAILASRLSSRLHLGTTQLSVRDRMLWANVGAVLALGVSVFAGLGVGAWAVGQLVGSELGLLTLLTISLGSGLSIAVLAVVCSIVTTALSYRWGIDPDDTTIPIVTNVVDVFGMLVFIGLAGWIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXY5</accession>
    <name>U1MXY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01004</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88858">
        <property type="protein sequence ID" value="ERG88858"/>
        <property type="gene ID" value="J07HX5_01004"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165169_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
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            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
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        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88858.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="11649" checksum="38BD2AB76FDE2564" modified="2013-11-13" version="1">MPDSRVRFRDAAGTVRTGSWTVGTPGVDGRITAAGRAYDPETVVVLPPCEPIKIVCVGLNYADHAAERDATVPDRQSLFLKPPSAVASHGDTIPSGVPDRLRGRAGGRDR</sequence>
</entry>
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        <submittedName>
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            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="gene ID" value="J07HX5_01186"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="81"/>
        </location>
    </feature>
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            <begin position="75"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="19372" checksum="84CDF437D0340C05" modified="2013-11-13" version="1" fragment="single">MYVTDFVPTDEIETIATSFQRVLETGESVTVESAFETKAGERIPFEFTGAPLADANGEVRGLTGIGRNISARKKRQRQFEAVFNNTYQFTGLMAPDGTILEANKTALEFGGLDRDQLVGNKLWETYFFQISEQARAAAQEAVNQASTGEFFRDQLRVQGADRAAVIDFSVRPVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <dbReference type="EMBL" id="ERG89135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="28956" checksum="8D8B43D473903668" modified="2013-11-13" version="1">MVRVPPAAGANLVGGVLGVDTELDSVSVELDVRLVVRELLAGCNPELPLDDIDPREKLRHRMLNLDPSIDLEKVEVGLGAELRGAALAVVFDEKLDGTGVGVIRLARSLAGGRVDLLTQLRRQCCGRALLDDLLVAALERAIALAEVENRSVGVGENLHLDVAWVLEIPFEVDGVVVEIRCALPLGTLELVGCVRWCLDDFHSAAAATALGFDRNRVAVLLSKRLDCCCVGHRLGRPRNNRHASLVQQRASACLLAERSHCVARRANPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYB6</accession>
    <name>U1MYB6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01318</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="12750" checksum="E772E0076852F95E" modified="2013-11-13" version="1" fragment="single">MTTGGDGDDEYSGETDDDSREAAVGAEVDPSTNGAGHANAAGRVSLAADAQTDGVEQRSLTEQTTDRRSISAQVQLYWGLQIAAISLVVGLFAVGALSTTSLGMWAAPVVAGGLLVVGTVWVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYC7</accession>
    <name>U1MYC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">J07HX5_01328</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_362749_0_0_2"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
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        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
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    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="185"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="403"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="594"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="647"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="770" mass="84949" checksum="525D832E6AB5273D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYF9</accession>
    <name>U1MYF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell division GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01209</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89058">
        <property type="protein sequence ID" value="ERG89058"/>
        <property type="gene ID" value="J07HX5_01209"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1036659_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="28372" checksum="2E3FB098F0AA5965" modified="2013-11-13" version="1">MIARHLQISYELPVYALGVFPARSEVSLHTMNAVESLKTLQTAVDNTLVFSNDVLTPSGKPTQESYTQLNREIARRVQMICAASAPDTVADTQTQPQQVVDASEVIRTLDHGTTSTIGFAATTLNTQARTDGGVLSRISNVFYSQDDPPPAANPANQGAAHAIKTLTRKAVLRSTPLTDQPTARSALLLVSGPPDELDRAGLGEAQSWLSDDTGTAAVRTGDLPVANSTLCVLVLLSGVATPLSRWIDQRAVNGLPSDGTDAVAPLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYJ7</accession>
    <name>U1MYJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01400</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89245">
        <property type="protein sequence ID" value="ERG89245"/>
        <property type="gene ID" value="J07HX5_01400"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1264536_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="60"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="22841" checksum="ED77E83C3B9178B4" modified="2013-11-13" version="1">MGIGMGMGASLGSAVVCQLPGLCADLLAGSQLPVSVAVPLQAESDWAFIWDNRETLLLGTGVTILLTVASILLGFLLGLPAGALEAYGDGWGQAAVSAAGVVLRATPIVVLIVLFFFGLPIPSQLGAFPGLDIELNAFLTATLALGLRSAAYQSQVFRGTIQSVSEGQLEAARSIGLSGRSAVLYVVLPQRSGGRSPDFKRVYDCPQRHECRVRNWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYK3</accession>
    <name>U1MYK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01406</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89250">
        <property type="protein sequence ID" value="ERG89250"/>
        <property type="gene ID" value="J07HX5_01406"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077072_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="230" mass="24757" checksum="03A1E496AE0FA2BD" modified="2013-11-13" version="1">MQLGGDRECTACGTRWSYYDTGGVRCPDCESPRSVSVGESAEHTAGTATFDLTSLRAALADEPVGALADRAADQARTYLRQAGFVDAGVLQPFTAQYAAAAELRRAGRTAGRLSSLETDEQRYLLALLRGADRGDRPSPADIPDSFHPERGLAVAASVETYLRELQRVVVPDDQLARALATITTRRKRIEALDGAVEPTAAEQLFETTQTLYAAVNGDNTPLEQTIGQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYX0</accession>
    <name>U1MYX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01393</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89238">
        <property type="protein sequence ID" value="ERG89238"/>
        <property type="gene ID" value="J07HX5_01393"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2534534_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9269" checksum="2AE1F59A755955F3" modified="2013-11-13" version="1">MIMIADPSTFHLMAFSSEYIISKYRPTGETRPYCKYKNEGTAAIAVAPTISSIIPAANLRXXXXXXXYHFRCVSVRITEGSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYX6</accession>
    <name>U1MYX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01513</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89355">
        <property type="protein sequence ID" value="ERG89355"/>
        <property type="gene ID" value="J07HX5_01513"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2765890_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="69" mass="7216" checksum="D6B70FB854DCDF30" modified="2013-11-13" version="1">MSGVPGVIPRPTALSPRLSIKPRGAPPASRVDSRTPPAHAPGCERLLGLSRYLENKPNGCKSAIRGLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ52</accession>
    <name>U1MZ52_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoacyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01481</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89323">
        <property type="protein sequence ID" value="ERG89323"/>
        <property type="gene ID" value="J07HX5_01481"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1870649_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PTHR12649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="136" mass="14864" checksum="C1F8AAF530682352" modified="2013-11-13" version="1">MTCLWLIYHRVLTVDIVEAGRAHAFADKIEMMQCPTRLKSDDLXXXXXXXLQAAEAADRSARDDWRGDGQKKIVLQGESKRQLFTLADSAESEGLPYAVVRDAGHTQLDPGTVTTLAVGPASGDRVDLITGELALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ56</accession>
    <name>U1MZ56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01486</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89328">
        <property type="protein sequence ID" value="ERG89328"/>
        <property type="gene ID" value="J07HX5_01486"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010057_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="594" mass="65216" checksum="0D969BDBD0B9257E" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ68</accession>
    <name>U1MZ68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01646</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89485">
        <property type="protein sequence ID" value="ERG89485"/>
        <property type="gene ID" value="J07HX5_01646"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2856971_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="6981" checksum="E221EE3CB244B525" modified="2013-11-13" version="1">MMGQSDSERSRCQPPKRPTISDVRVRACVRFPILAALVPGVVFGCRHETLDKCTTAGRVAGHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ76</accession>
    <name>U1MZ76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01660</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89495">
        <property type="protein sequence ID" value="ERG89495"/>
        <property type="gene ID" value="J07HX5_01660"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2406232_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10465" checksum="E443990DD3D957CA" modified="2013-11-13" version="1">MSPVPTVTGRIFHAWRAIHLHLNTPRAFVSRCFCLCRRYDEISDCGSPWHPCLSALKKSITGGRLSRPRRPNCGCSWVRAEKTMICGPVRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZI1</accession>
    <name>U1MZI1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase beta</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">J07HX5_01785</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="17">Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89615">
        <property type="protein sequence ID" value="ERG89615"/>
        <property type="gene ID" value="J07HX5_01785"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017729_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
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        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
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        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
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        <property type="entry name" value="NT_sf"/>
    </dbReference>
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        <property type="entry name" value="PHP_dom"/>
    </dbReference>
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        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022311">
        <property type="entry name" value="UCP005047_YshC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HHH_8"/>
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    </dbReference>
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        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005047">
        <property type="entry name" value="UCP005047_YshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47802"/>
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    </dbReference>
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        <property type="entry name" value="SSF81301"/>
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    </dbReference>
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        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
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    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="POLXc" evidence="20">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
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        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
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        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
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        <location>
            <begin position="348"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00020020"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025610"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ERG89615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="577" mass="61515" checksum="FA4D91027EAEBE79" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZW3</accession>
    <name>U1MZW3_9EURY</name>
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        <submittedName>
            <fullName evidence="4">Arylsulfatase A related enzyme</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">J07HX5_01922</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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            <begin position="4"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
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        <location>
            <position position="48"/>
        </location>
    </feature>
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        <source>
            <dbReference type="PIRSR" id="PIRSR600917-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="475" mass="52747" checksum="FE4A65C8566A9A2C" modified="2013-11-13" version="1">MAAPNVLLVVLDAAQASRVYDETVMPNVTQLASGAATYTNAYTTAPWSLPSHASLFTGTHTSTHGADADTPQFTPDRQPLAARFEAAGYRTLAYSNNFWISPSFGFDTGFDEFEVGWELFSGGQGFAEVGKEEASLRGRLRKLAPKLLSRDAPKTLANLLFLMTVWDRHDSGAYLTTRRAKRWLSGDEPFFMFLNYREPCLTYDPPAEYISKVTPTGETPPDPGSVNQDPWAYATGEIEMDETDFTRLKTLYDAELRYLDARLGQLFEALDTKGLLDETLVIVTSDHGENIGDHGLMDHQYCLRDTLLHVPLVMRGPGVEPGRRGGLVELRDLYQTLLAAAEIEGADPTVDLRDRPSRDAIAAEYRTPMPSIDRLRTEYGDLPESVRGYDRGLQAIRTEDWKLIRGTDGSERLYNLADDPNERVDVSNATTDVRDRLAGQLRDRLPPLERADATAGTESAVPAVLGDRLEDLGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZX5</accession>
    <name>U1MZX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01783</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89613.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="23"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="295" mass="31490" checksum="45E1261CC579839A" modified="2013-11-13" version="1" fragment="single">FGRRFARIADRHAQCRRVTAPWGESFDLDAVAAAITDETALVTMVHNETSTGLLNPVAGVGRFAREHDTLFAVDGVTSIGGDVFCIDDWGIDIAITDAQKALAAPPGISAVYVTDAAAALINGESAPFYEDLDWHLRKAEDNQTPFTSAVPLFRAMAAAVEAINREGLSARIRRHRRQATAFRKGFTAMGLSLFPEPTGATVRSNTVTAVSLPDRVREDPTAFFGAVEERNVSLSGGQAHLGGEIFRVSNMGRLDDAQILRGVRTVGEAMGDAGVPVSRADTEAGLAAAQRVLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZZ6</accession>
    <name>U1MZZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01952</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89780">
        <property type="protein sequence ID" value="ERG89780"/>
        <property type="gene ID" value="J07HX5_01952"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1464115_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="184" mass="19298" checksum="3044B7A0327F0A55" modified="2013-11-13" version="1" fragment="single">DHTEGDSAVSDSIAVAQTANERMADRVDDFTTLAQYGQTVDRLEAVALRAAAEDAWSKAEPGSTELQVDGGATINADPGRLRELLINAFVFAVQNGAETVTVEPHDSGFVITGDGEPPGDAADYLAFGESVPDAESGMKLPSARAFARVHGWSASIDTDYQAGVRFVVSDVQVNAVDRSAQPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N019</accession>
    <name>U1N019_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01972</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0179 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89800">
        <property type="protein sequence ID" value="ERG89800"/>
        <property type="gene ID" value="J07HX5_01972"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2799653_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005369">
        <property type="entry name" value="UPF0179"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03684">
        <property type="entry name" value="UPF0179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7261" checksum="51EE58B753816606" modified="2013-11-13" version="1" fragment="single">NAYAGNQAALEGPCPHTECPSHEYCVPAGVGFDESNQIDTVTGDPPHEYCQLDRDLTLVEFQPPEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N074</accession>
    <name>U1N074_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01890</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89718">
        <property type="protein sequence ID" value="ERG89718"/>
        <property type="gene ID" value="J07HX5_01890"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2103406_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="13826" checksum="CC8F5316E284B9F6" modified="2013-11-13" version="1">MTNKRLFKIPLDPERIGAVREHLAELEDRRETFERGLALGKMNAETAWLDETEPALCCLHEEHDDYSADVEAGKLDDQLQELSADHHAFFRTVAAPDHDRPEGLVEFERLFSVSARDRIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0D4</accession>
    <name>U1N0D4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methenyltetrahydromethanopterin cyclohydrolase</fullName>
            <ecNumber evidence="4">3.5.4.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methenyl-H4MPT cyclohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_02073</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin</text>
            <dbReference type="Rhea" id="RHEA:19053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58018"/>
            <dbReference type="ChEBI" id="CHEBI:58337"/>
            <dbReference type="EC" id="3.5.4.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MCH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.27" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89900">
        <property type="protein sequence ID" value="ERG89900"/>
        <property type="gene ID" value="J07HX5_02073"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1880985_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018759">
        <property type="term" value="F:methenyltetrahydromethanopterin cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003209">
        <property type="entry name" value="METHMP_CycHdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02289">
        <property type="entry name" value="MCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="13988" checksum="9F2A178053F4C9AF" modified="2013-11-13" version="1">MEPLNRLATELIDEAIDFADELAIDVYTLEGDAAVVDFGVDVPGATEAGLLLAEIQTAGLATIQTAVADAGGRPRTHVELSTDHPALALLCASKGGWELSVDGFEGLGSGPARALSPKSRSTSRRATARLPTSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0E9</accession>
    <name>U1N0E9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01970</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89798">
        <property type="protein sequence ID" value="ERG89798"/>
        <property type="gene ID" value="J07HX5_01970"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1566067_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="62"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="170" mass="19125" checksum="ADBC2240D7E0A53B" modified="2013-11-13" version="1" fragment="single">AEWARQKKSRRQDHLLHALSKDIVEQCAKRDVETIAVGHPKNIRDDSDWGRHGNKRLHDWAFETLLSHIEYKAEERGISVERVPEGKLKTSKTCCECGKEADSNRVERGLYVCESCELVANSDLNAAENMRSTVTPSPSQDRSNGCLAQPSVRLFDKSTGRVAPQEQVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0G7</accession>
    <name>U1N0G7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02113</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89940">
        <property type="protein sequence ID" value="ERG89940"/>
        <property type="gene ID" value="J07HX5_02113"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1860676_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="130" mass="14540" checksum="8D7055B43F234A46" modified="2013-11-13" version="1">MREVEASQFVQTYPKRIAGTLSPDTVLEAEGSFSIRDIDADGDRITVGGYGVELVFEFAARDNGIEYDQVEGPLETLRTTLTYEHENEGTRLTARSKVAAPGPGFMDRLAAWKRRGELRRAVRGIAEEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0I3</accession>
    <name>U1N0I3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyl-CoA synthetase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02133</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89960">
        <property type="protein sequence ID" value="ERG89960"/>
        <property type="gene ID" value="J07HX5_02133"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052104_2_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="10365" checksum="E758091CAC7140D9" modified="2013-11-13" version="1" fragment="single">MGVLIDQETRVLVQGITGAAGRFHAERMNNHGTNVVAGVVPGNGGTDVAGIPVYDTITDAVRDRAPTTAVSFVPPAVAADALFEAIDAGLELVVAVTEGIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P333</accession>
    <name>U1P333_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00023</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87882">
        <property type="protein sequence ID" value="ERG87882"/>
        <property type="gene ID" value="J07HX5_00023"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1052129_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="264" mass="30040" checksum="D35B95A4C531E613" modified="2013-11-13" version="1">MFRLDPPLIVPLLCHGKPIYSLTPLSPFATTANSHXXXXXXXKNYQPKPPDEILDRAIENRQQEFASFETEIEASRDAFLEKFQTQYDQANKDVSPTADLLHVVDVGEPSESETRAIYRSAGQTVNVMTKSLEYYNRIRPAVVDAVSRGVEVELLFLHPQHLTAANAETQRTVVNELRREFPTVTLRFSDRQLPWRGTLADPSMEYDTGVAIFLVEEKEIPLHMRQAAITENGSFVAGLRRYFELVWEHESTALAAIEYDEHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P350</accession>
    <name>U1P350_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00048</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87907">
        <property type="protein sequence ID" value="ERG87907"/>
        <property type="gene ID" value="J07HX5_00048"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2366091_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="5">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10467" checksum="2216AEDE796544E4" modified="2013-11-13" version="1">MEQVAPNHTSQRCSRTDCGFTHEDNRHGEHFECQKCGYEVNADDNGAKNIGLRYARKRTHRLRSSPKSGSGDAGVDLRITGGTLNGKSHRQIAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3S3</accession>
    <name>U1P3S3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00305</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88162">
        <property type="protein sequence ID" value="ERG88162"/>
        <property type="gene ID" value="J07HX5_00305"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2127740_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="11928" checksum="3885D0BE436AA48F" modified="2013-11-13" version="1">MRGKSRVRVVLAERTAVFPTDCVRILCSSSLILDSASLPAGAQNNQYVIYWRATLGTVGTVRADRVNGMLDNTATTNAATLAPATGYRFSDGSVAVNCSIARSAYPSARSGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P400</accession>
    <name>U1P400_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00380</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88237">
        <property type="protein sequence ID" value="ERG88237"/>
        <property type="gene ID" value="J07HX5_00380"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037493_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021516">
        <property type="entry name" value="DUF3179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11376">
        <property type="entry name" value="DUF3179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="409" mass="42740" checksum="8ACC21D559952374" modified="2013-11-13" version="1">MSREPGQSPRRRSLLGGLGALAVTGLAGCVQLPSAGDGDGGDGGDAGATDVTDGLPGSTASGAVVGEPPDEELPVGPAALTRGAPKDGIPAIVNPSFGADWSGFEAETRSRFGSGNTIAPRLADDDLVVGVARDGEARAYPLKLLNYHEIVNDTFDGPLLVTYCPLCRSAIVAKRRAGGEPTVFGVSGLLYRNALVMYDEATGSNWSQILAQAITGELTGERLELLPSTLATFGEWRASHPDTTVLRPPPESDTLGAGTGVRDYATDPYPGYDQSDQIGIGGEFDDDRLGPKTKVVGVAVAETARAYTAEAIETEGPIKDTVGGLPIVVTNTPNGTPIAWSRRVGDETLSLGIADERHLAGGGSRWRRDTGVAVDGPFEGERLAQANSVSALFWFAWLDFYPETELYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4G0</accession>
    <name>U1P4G0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein, putative amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00516</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88372">
        <property type="protein sequence ID" value="ERG88372"/>
        <property type="gene ID" value="J07HX5_00516"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055029_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024087">
        <property type="entry name" value="Creatininase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003785">
        <property type="entry name" value="Creatininase/forma_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35005">
        <property type="entry name" value="PTHR35005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02633">
        <property type="entry name" value="Creatininase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102215">
        <property type="entry name" value="SSF102215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="28705" checksum="7B555DBF5D0C8561" modified="2013-11-13" version="1">MKLADQTWPELTSHLESNSLALVPLGSTEQHGPHLPLATDHLIAEAFAREAAARAGVLCTPTITVGVSPHHKQFAGTMWVDAPVFRDYVESLTRNLAYHGIDRVIYVNAHGGNVSHLREVGRRLRDEELLYAIEWMWNNSIEELVEEVFEQTGPHGGPKETALIQYLAGELVREDRLTDARDNGLTAWENADGLTVHGARTFYDSADNTDNGVLGDQTDATAEKGERLFEAATAQLVRLVEWLNDQTFQTLMPEPRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4L4</accession>
    <name>U1P4L4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate:ferredoxin oxidoreductase related 2-oxoacid:ferredoxin oxidoreductase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00597</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88452">
        <property type="protein sequence ID" value="ERG88452"/>
        <property type="gene ID" value="J07HX5_00597"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1002849_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:sulfur compound biosynthetic process"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="THDP-binding"/>
    </dbReference>
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        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="27"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="277" mass="30252" checksum="5D79DBB6ECA10F8F" modified="2013-11-13" version="1" fragment="single">FAVLRALKGAMPAVGRSPEEVLLVTGIGCSGKLSSYFESYGYHAIHGRALPVARASKLANPGLEVVAAGGDGDGYGIGGNHFMHTARENHDMTYIVFNNEIFGLTKGQTSPTSPKGHKSKTQPHGSAKAPVRPLSLSLAAGASYVARTAATNPRQAQEILTEAIQHDGFAHIDFLTQCPTWNKDAKEYVPYTDVQEAEDISFDVTNRREAGEAMYEAESRLYEGEVLTGRFYQAEERPSYGDEKRRTGEMPDEPLAERYADSDDWAQPASELIDRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4L9</accession>
    <name>U1P4L9_9EURY</name>
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        <submittedName>
            <fullName evidence="6">Sec-independent protein secretion pathway component TatC</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">J07HX5_00602</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
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    </dbReference>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11242" checksum="2EC70680B885AEF4" modified="2013-11-13" version="1" fragment="single">GSTTFGWLVTYLTVGIGLLAMVPATMLLFHHGSIVSFSRMRRSWRVVVFAVFVVAGVFSPGGLFTMFMIAIPTALAYVLGLGLLWMYDRIGRAVPQGRTKTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P504</accession>
    <name>U1P504_9EURY</name>
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        <recommendedName>
            <fullName evidence="2">Toprim domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88617">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00007">
        <property type="entry name" value="DNA_primase_DnaG_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020607">
        <property type="entry name" value="Primase_DnaG_arc"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="165"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="394" mass="40697" checksum="C9BE68243AF7A074" modified="2013-11-13" version="1" fragment="single">MHTAKYLIHAEIRTSGVVERSDVVGAVFGQTEGLLGETLDLRSLQDASKVGRIDVDIDATDGQSYGSITIATALDKAETAVLAAALETIDRVGPSRSEVTVVEIEDARAAERRAVVGRATELLNEVEEASLTDDQIVAEVRERARVADVSEYEGLPAGPRVADSDAVVVVEGRADVRRLLTAGIKNAVAVEGTDVPEAVATLTTDRTVTTFLDGDRGGDLILRELTQIGEIDHVAFAPDGESVEDLDRDAILSALRRKLPYAQVSADDSARAVFGADGEMSGGANSKTQASPEAEAESTTNRPAGSTAEAVEEPAVAPEVATAGASGSAAATTEARPPATLQEHVAAVIGDETGTVRLLDESFAKLGEADAAAAFDAVADAETVPATVVVDGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5G8</accession>
    <name>U1P5G8_9EURY</name>
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        <submittedName>
            <fullName evidence="4">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">J07HX5_00928</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88782">
        <property type="protein sequence ID" value="ERG88782"/>
        <property type="gene ID" value="J07HX5_00928"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="30"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="317" mass="34072" checksum="B6C7AFD1A808BEE1" modified="2013-11-13" version="1">MTTSDTDPTRTPGGNTTGNGDTDTGFRPAIDAHTHVFPEKLMAAIRAAISAEAGWSFDNPVTRPAIETTLREAGVLRYVALPYVTEPGAAAELNSWLLEQAAESDRLVPFATVHPDDDAPGAIARRAFERGARGLKFHCPVQGCSPADPGIAPALEAAAAADRPVTYHGGTAPMFEDSPHVGVEPFSEVIASYPKLRVCCAHMGTYDTDAFLSLARTHEQVYLDTTFAMSTQATETMGFDPASIADETLIELSGSIMYGSDFPNIPYRYREERAGLLDRELPETVVRDLFFETAQEYLRLDLSPASGPGETALDAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P619</accession>
    <name>U1P619_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01142</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88992">
        <property type="protein sequence ID" value="ERG88992"/>
        <property type="gene ID" value="J07HX5_01142"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109222_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="19310" checksum="920C0F94492B3543" modified="2013-11-13" version="1">MSERDRQLEQTVDTDVDDLELDTALDTDSSLDLDSETVRDRSSGPAPAAREDDGIGARVKRRFAALATTRELIAAFVTTILGLVVVGGLLPIPAVGNLIGVFAGGFVYGLVAGDSPYLQLAVAGGLATAAWTVLGNLTVALLGSGVTIATAGLVGGLIAAVAGGYFGRDLRQGLTQDVGGDSGPGPDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P655</accession>
    <name>U1P655_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01183</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89032">
        <property type="protein sequence ID" value="ERG89032"/>
        <property type="gene ID" value="J07HX5_01183"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490321_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9725" checksum="4F25CDD7D445DC49" modified="2013-11-13" version="1">MSGGTDGRHLARVGVQSYGFMTLRVDNLPLLYLLHSSDKRVPVEAIRWRTDRVFEAVRGHAATEKLSYFRLLLPLLLSVVMARVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P684</accession>
    <name>U1P684_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01219</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89067">
        <property type="protein sequence ID" value="ERG89067"/>
        <property type="gene ID" value="J07HX5_01219"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2839253_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="7193" checksum="873CB4FDD4E26388" modified="2013-11-13" version="1">MTADPTMRAGRNGFIVLLVALLVAWAYQFALANENNQLLFGLWALGAVSFYASKYYYDRTAGEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6D2</accession>
    <name>U1P6D2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01274</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89122">
        <property type="protein sequence ID" value="ERG89122"/>
        <property type="gene ID" value="J07HX5_01274"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083552_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="18"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="138"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="20993" checksum="1F2D8069D91BDB88" modified="2013-11-13" version="1">MAYRSVAASGKAQFVVGDSEFLGYTDRVPTVGAAEQFIETRRGAHPEATHVVPAYRIRGSPVQSWASDDGEPSGTAGSPALTVLEREALENVVAVVVRYYGGTNLGVGGLARAYARGVKAAVADAGITDREPHDTLRVTVTYDDSGTVRGVLESVGATFETSYEATVVFEVRVPTTTAAALRNQLQSATSGRATIERAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P708</accession>
    <name>U1P708_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00032</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87891">
        <property type="protein sequence ID" value="ERG87891"/>
        <property type="gene ID" value="J07HX5_00032"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477037_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="571" mass="64016" checksum="272D8B03DB751AB2" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7I2</accession>
    <name>U1P7I2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)</fullName>
            <ecNumber evidence="5">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01682</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89517">
        <property type="protein sequence ID" value="ERG89517"/>
        <property type="gene ID" value="J07HX5_01682"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026099_1_0_2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="10">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="11">
        <location>
            <begin position="97"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="29408" checksum="2BE8110E73970A11" modified="2013-11-13" version="1" fragment="single">MELGLVVLDGWGINPDPERDAVAAATTPTIDRLTEQGAAAQLQTHGRAVGLTAGQMGNSEVGHLTIGAGRVVRQESTRITDAIASWRGDPQGDDPPLDKNPALAQAFAAARRTGGRVHLLGLVSDGGVHASQAHLHALIDLAAERGVTAVTHAFTDGRDTPPTSATDYLERLAKHAAAAGTGQVATVTGRYYAMDRDENWARTQRAYNAVVHRDAAAAASNPVAAVEAAYDRGTTDEFVEPTLIEGRPALVDDDSVVVVNFRADRARQLTRLLVGDCAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7J3</accession>
    <name>U1P7J3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IMP cyclohydrolase</fullName>
            <ecNumber evidence="3">3.5.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">IMP synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Inosinicase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purO</name>
        <name evidence="5" type="ORF">J07HX5_01692</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal IMP cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.10" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89527">
        <property type="protein sequence ID" value="ERG89527"/>
        <property type="gene ID" value="J07HX5_01692"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1352116_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00705">
        <property type="entry name" value="IMP_cyclohydrol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010191">
        <property type="entry name" value="IMP_cyclohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020600">
        <property type="entry name" value="IMP_cyclohydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036795">
        <property type="entry name" value="IMP_cyclohydrolase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07826">
        <property type="entry name" value="IMP_cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004866">
        <property type="entry name" value="IMP_cclhdr_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75569">
        <property type="entry name" value="SSF75569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01922">
        <property type="entry name" value="purO_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMP_cyclohyd" evidence="4">
        <location>
            <begin position="2"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="21342" checksum="D1CA05315E8DB628" modified="2013-11-13" version="1">MYVGRFVVVAPRVGAYRVSSRSFPNRKATDHGDRVSIVPTAAAPNSDNPYISYHCIQRTDSGVVLGNGAHVDPIAEKLARGYPARDALVTALLTLDFEKDEYDTPRIAGVVGTRPSSDGASSQTPVAHIGIVRRDGLQVDRVTEPTLVATYERTTPEPFGLEADEAAAAARAVYEHPFDHRVCAAGVVVDDGVETAVING</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Y9</accession>
    <name>U1P8Y9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00747</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88601">
        <property type="protein sequence ID" value="ERG88601"/>
        <property type="gene ID" value="J07HX5_00747"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="319" mass="33968" checksum="82BDF0DD7674D7D6" modified="2013-11-13" version="1">MSTGTQRSGDGTTVTRSGSWAVNYLRDHTLHALVVVLFVLYPFAYDALVGQFGLTAETVLLQPRTMLTVLWLGLFAMSFDFVSGYTGYLSFGHAAFFGIGAYTVVLGYNGQLPLVPAELPFMLLLVLGGLLAAVAAVLIGLIAFRLSGVYFAMITLGVSEILFVASGNFDFLTPGGTDPSDGVTPGIPTDVETFDPELGVPFVDALQVQLGAFGDTSVLGLDLAPFFTEVNPAVVASYFAIGAAVLISYLVMQRIIHSPFGRVMIAVGENEERARAIGYNTFWYKMGAFVISAFFAAVAGGLLVGYTGFVQPANTFFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9H4</accession>
    <name>U1P9H4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00927</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88781">
        <property type="protein sequence ID" value="ERG88781"/>
        <property type="gene ID" value="J07HX5_00927"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="347" mass="37659" checksum="6DEB5912C284F83E" modified="2013-11-13" version="1">MPCGEYFTSYVSRMGLVRWRTERIALVLALPIPFLLPMFLDPGTVSVITQIYIFIIAVLGLNVMLGYAGEIVLAQAAFMAIGAYSTAQIIANVGMGLLPAVLVGGLFTAVVSILFGLPSYRVKGFYIAISTLALQFITEWFFEQQRFEPIHGGPVQTDIPTEIALVDALGVINISSGQDIYYFAFALMTVVALVTLNISRTGIGRRFRAVKENDLSSAVLGINVFRTKLLAYGLGGFIVGVAGGLYAFYLTSFTPGQFGIELTLEHYLMLLLGGIGRVWGAVIGVSVVVLLQEELDGILQEVSPQATSLEPLFFGVVIIVYLALEPKGIVAGLGQIKEYLRSWPYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9X5</accession>
    <name>U1P9X5_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Methionine synthase II (Cobalamin-independent)</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_01037</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88891">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="2">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="239" mass="25453" checksum="46E539112E130564" modified="2013-11-13" version="1" fragment="single">MMTASAPSIQTTHVGSLPRSPRLRELLTGDDTDTNKTDTTAAFEEAVTTAVRTVVGRQAAIGLDIANDGEQSRVAYSVDATTRLSGFSNGTVEREWPADLDAFPDYGEALLGASDTIGGPVAVGPIEYTDSTALKRELTRFPDATAAEGVSFPGRFHTAPSPGAVLRFTETDHHDTPEAYVFDLADALATEYELVAETGATLQIDAPDLLAGFTLTYKDDSVAQFRERVATHVEALNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA22</accession>
    <name>U1PA22_9EURY</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01099</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88951">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076271_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="300" mass="33270" checksum="794CEFBF092D8BD3" modified="2013-11-13" version="1">MTAEKTQRHSQAHRHRHSLSQSPTAVFDSIDAALETELRQNTVERDAFQAFADRVGEISVTTEAPDSVPPTIGVDTTGPSRLQAVRVAYEETVMATPHYKTEYGESYPVNLRAELGADVATAMLGARRLSRRHKHIVLGAVTDVLTARRQLIAGLDAEQASVDALREPVCTLVSDLDRLEAAIDRPMATDSARADYEPQLRDAYRRRLSVFEDRCHELIDRRQSEIVDLRHKLSLSVNQPDLPTYLYQELPADHPVVATLTACLNVRASVWPRSSRPVTASRTPDWTRVTGTAPASRGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAG9</accession>
    <name>U1PAG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Archaeal/vacuolar-type H+-ATPase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01248</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89096">
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        <property type="gene ID" value="J07HX5_01248"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1727175_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="15998" checksum="AD57E47566945E56" modified="2013-11-13" version="1">MRTSSASDSSFSVPTYELAEFAVPLVHTLSYTRITAVLVSKAGMALAANLLYFGAYQDAEGYHYLFNKSPDEVGGAGSGEELIFGGVANAGIEGVILGLPILIVGHATVLAIGGTAGLQAIRLEYVEFFEKFYEGGGRSYEPFGRSQSTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAI5</accession>
    <name>U1PAI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01263</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89111">
        <property type="protein sequence ID" value="ERG89111"/>
        <property type="gene ID" value="J07HX5_01263"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712650_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7920" checksum="08AD2C781D1F46B0" modified="2013-11-13" version="1">MIIKQHSCVLNGSKTNKHGRVDSLSRRERLDLAAPVATVLETGKILSVPFDLPVVHARGDDHREQNCVDCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAJ6</accession>
    <name>U1PAJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01273</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89121">
        <property type="protein sequence ID" value="ERG89121"/>
        <property type="gene ID" value="J07HX5_01273"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2839255_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="7247" checksum="F151615A198B65AE" modified="2013-11-13" version="1">MDIEGYLRWFAKLGLFYQILIAGSVLVGMVALITSLALRSPFFLFIAVFWFLVAPASISFASARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAR2</accession>
    <name>U1PAR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01339</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89186">
        <property type="protein sequence ID" value="ERG89186"/>
        <property type="gene ID" value="J07HX5_01339"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3362487_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="35" mass="4217" checksum="48066E48E3604B8F" modified="2013-11-13" version="1">MASTDKYILKIILKLYYPVIIIIDCHISRNRHESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAX5</accession>
    <name>U1PAX5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type amino acid transport/signal transduction system, periplasmic component/domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01401</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89246">
        <property type="protein sequence ID" value="ERG89246"/>
        <property type="gene ID" value="J07HX5_01401"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="45"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="28673" checksum="431C847CAB3856B1" modified="2013-11-13" version="1">MAGCVGGDSGDGGDDADGGDDGGGDSTDSGDGGDDSTDSSDEVETITPGTAPGFAPFEFRNDDNELVGFDVDLATAVIEAAGYEAASPENWVTIEFDTLIPSLRRGDMDLVAAAMTITEERDEQIDFSESYYEANQAVLVREDDIDPSEFADLEGRRVGAQSGTTGESTAESELVEPGLIDGSQYNSYGNYVLAINDLENGNIDAVVIDTPVANNFADDRSVQVAFVFETGEEFGFGMQEGDDRISDINEGLAEVRDNGTYDELVSEYFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBM7</accession>
    <name>U1PBM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01637</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89476">
        <property type="protein sequence ID" value="ERG89476"/>
        <property type="gene ID" value="J07HX5_01637"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020892_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="56" mass="5804" checksum="BEE3ECFBA5B202DC" modified="2013-11-13" version="1">MGVGKHLLNGIVSVIISVGATVAMAENDTYDLGEMTLAVAVSAFLSGFFTSYFASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC07</accession>
    <name>U1PC07_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytidine deaminase</fullName>
            <ecNumber evidence="5">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01791</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89621">
        <property type="protein sequence ID" value="ERG89621"/>
        <property type="gene ID" value="J07HX5_01791"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097262_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="14249" checksum="A95C997B798833A0" modified="2013-11-13" version="1">MDETALITRARTALEQAYVPYSEYAVGAAIETTSGGVYTGCNIEVANYSNSLHAEEVAVGKATSDGHRQFDRIAVSSSERDGILPCGMCRQTLTEFCDQEFVVLCDTGDGTARYQLGELLPDAITNEDLEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCM7</accession>
    <name>U1PCM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02013</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89841">
        <property type="protein sequence ID" value="ERG89841"/>
        <property type="gene ID" value="J07HX5_02013"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176022_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7211" checksum="E990BFA748B4D74C" modified="2013-11-13" version="1">MQRNVGRVDAAARIVLGVSLLGAAGLVVAGVVTTPVVSAVGLALAAIVLVVEGATRRCLLYGLLGIDRCPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCT5</accession>
    <name>U1PCT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02069</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89896">
        <property type="protein sequence ID" value="ERG89896"/>
        <property type="gene ID" value="J07HX5_02069"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2127744_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="10668" checksum="AD5B4D2A68312C89" modified="2013-11-13" version="1">MLCSPSVNVSXXXXXXXSVVPGLGAIAGGSVGAYLYDSDSGTRVGGVTGLVAFALTLPLLGSIGVGMIAGGMAISELAGGAALAGIIAVSGLLGAAFSTGAGALGGYLIDRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFK5</accession>
    <name>U1MFK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00045</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87904">
        <property type="protein sequence ID" value="ERG87904"/>
        <property type="gene ID" value="J07HX5_00045"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134269_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="12970" checksum="FA8A9BDCFA493CFE" modified="2013-11-13" version="1">MDQVDFDPSQLVEAADGVYLQQLATAEEMSMQYVLIEPGGVAPMHKHRHEQSGFILQGTPTFRIGEEKKEFMLAANQSYDLPGNVYHEVENEGDVPVRNIDMFAPPRGHPAWKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFQ0</accession>
    <name>U1MFQ0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00120</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87979">
        <property type="protein sequence ID" value="ERG87979"/>
        <property type="gene ID" value="J07HX5_00120"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143932_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016694">
        <property type="entry name" value="UCP017292"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017292">
        <property type="entry name" value="UCP017292_Znf_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="SSF161219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="13047" checksum="9E873A7B90E4EEAA" modified="2013-11-13" version="1">MTDTAAETDTQFGVPLRGVEVDAQTRCLHYGTDRDVIAIQFPCCEVYYPCFACHAAVTEHTARQWPTDRFDESAVFCGVCRTPLSITAYLESDNACPACDAAFNPGCQDHHDRYFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG02</accession>
    <name>U1MG02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00252</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88109">
        <property type="protein sequence ID" value="ERG88109"/>
        <property type="gene ID" value="J07HX5_00252"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036524_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="16627" checksum="F62352029630EF9D" modified="2013-11-13" version="1">MTTSIICLRKGTRRGPATTTTAITRILRDAGVDDELLSPVQRCVAVHDELAIHGDELAPATIEVAVLWDADNLDAMGAIGVARAFTFGSVHDLTLWDPDGGAYSTLCHFEDRLLRLRGELHTELACQLAADRQAFLEAFHERFRAEWHSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG38</accession>
    <name>U1MG38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00302</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88159">
        <property type="protein sequence ID" value="ERG88159"/>
        <property type="gene ID" value="J07HX5_00302"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097039_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="215" mass="22814" checksum="231B107C515B9F27" modified="2013-11-13" version="1">MHRRRVLTALFAAGLTGVAACMDTTDEQPAGEAASTDSEAGGDAAGANNTDTNQLDGVSGRSTDGNATDEKRSETPAGLDWPTGPYADYDTTQVTVRSDDKAAASVRAAIADTAQTRYTGLSNATALPDGAGMLFVFTDEGDRTFVMREMDFGLDIIYANADRTITSVHHADAPGPNEDGNEQDYPGYGQYVLEVPQFWTDRNNITVGGRISFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG77</accession>
    <name>U1MG77_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00352</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88209">
        <property type="protein sequence ID" value="ERG88209"/>
        <property type="gene ID" value="J07HX5_00352"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1006862_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="28610" checksum="4573D251D2884337" modified="2013-11-13" version="1">MLTAALPATDPRLDAPSVGGGDDSVSGGWDSIHTVFNSNAQSESELDPEQDNDDHDRSSPDSDGLTLSVERPLEAGGETVVTVHDESIFSSAEHEILVDGEPVGVTSDGERNVSVPYTKEMTIGLSDEPLSKTFDVQTDGSISLDKPVAQNRNVSFSLTVGTTPLPDTRVTMNGQSVGVTDDKGRVSARMPERVGSVELVAERGPVTANTTVDLPPPEVIVTSPVVLPGLPAPVSVTADGVGVPNVTVSAAGAATARPTRTAARALCYRSTAKPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG85</accession>
    <name>U1MG85_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="2">6.3.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00362</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88219">
        <property type="protein sequence ID" value="ERG88219"/>
        <property type="gene ID" value="J07HX5_00362"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047116_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="7">
        <location>
            <begin position="81"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="8">
        <location>
            <begin position="198"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="38358" checksum="B257488157120FF6" modified="2013-11-13" version="1">MSDDPAAGQDTAESTAEGQNDDANGPENGKHSENDNGSGLTYADAGVDIAASETATQALIGAVAGDPPTDGAYAGLYDLGDQSLALTTDGVGTKLLVASAMDEFSTIGIDCVAMNVNDLVAAGVRPLAFVDYLAVDEPDAARAAELGEGLSAGADAAGVALLGGETAVLPAVVDGFDLAGTAAGLAPNANLFPGEAAPGDALVGFASSGIHANGLTLARQSVTREYEYTDPVPFDSARSVGEALLEPTRIYVEYLDALRRHDTRAAAHITGGGWRNLRRMGAFRYVVTDPLPAQAVFGLVQSTGGVSDAEMHRTFNMGTGFVAALAPAHAEKLAAETDGEIIGRVRERTDEHHTDDTTPEAESDGGTVSVRGIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGJ7</accession>
    <name>U1MGJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase (Metallo-beta-lactamase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00483</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88339">
        <property type="protein sequence ID" value="ERG88339"/>
        <property type="gene ID" value="J07HX5_00483"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1860637_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14398" checksum="BD9B03218BABCE91" modified="2013-11-13" version="1">MAECVGAPEDTAEDPAAADESAEPATGVLEVQYITVSQAASTLIVGPGGETLLIDTGDFRDNGQAVVEYLERQNIDRLDCLVTAHPDADHIGGHARLIDRLKTTDAGVGVIYDPGITATTETCEAYLDAVATQRQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGS4</accession>
    <name>U1MGS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00564</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88419">
        <property type="protein sequence ID" value="ERG88419"/>
        <property type="gene ID" value="J07HX5_00564"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2340034_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="97" mass="10468" checksum="D0C5B98CBF4FC9FA" modified="2013-11-13" version="1">MLMIQVALTLLPAGVLVVLAAVLWVSVHRVPEETVEIVVSAGEEQRVLGPGTHVLSPTGVQTYRIDPEAMVYEAPSGSLPVPNELRDEVSRVVNEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGV0</accession>
    <name>U1MGV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sec-independent protein secretion pathway component TatC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00604</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88459">
        <property type="protein sequence ID" value="ERG88459"/>
        <property type="gene ID" value="J07HX5_00604"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741037_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="404" mass="44197" checksum="4CAC68EDE8DBE71A" modified="2013-11-13" version="1" fragment="single">MARTLDDDTMRTLASGRQTLMSVLSNAQGRLKRVFLVFATAFLLTFFLLRRVIWDQLQTDLVYNQMSLETAQATEIVVTDPFNIILLQTKIGLVVGTIFALPFTIWYGRSGLKRRGYWPSGSVPRWKLVAFGFAVALLFVGGVTYAYFIFFPVMFKFLASVAINAGFTPTWSIVMWTEFVFFLSLSFGLAAQLPLAMTASARTGVVPYETFRNNWRYAVVGIFVFGALFSPPDPFTQFMWGVPLVVLYFISLGVTKFAVLSKRAGDQVSTATVTRDGWNVLAGSWLAAGLATYVYLLEGGLTATNDLLAWIGSSRQLPTAPDLAVGSFSPAVVGATIGAITGLFATVAVLFYLRIAALERVTADEETGVSSLDLASMDAAAVRAAPLERIAEFDHDQAVTYAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH46</accession>
    <name>U1MH46_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00750</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88604">
        <property type="protein sequence ID" value="ERG88604"/>
        <property type="gene ID" value="J07HX5_00750"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="67"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="28660" checksum="67E62A90F970F2B4" modified="2013-11-13" version="1">MGIFINQPPVGFSVSSSQIVLNNCAGEVVSSGPRETFCQGSWQFPFGTDGRGQPLDEVVLSGSRPVVYAVGITVGLIVPLAVAVGVTAGYYGGLTDDLLMAYVDFQLSVPAVLVYLIVYIFIANSPFVFVVAFGLLSWGSIARLVRSETLKQREEGFVTSARAVGASDLTIIRRHILPNITNSVIPAAFHLSAIIILTEAGLSFLGFSAFEQSWGLTIGDSLQNQSGTALDVWWVATFPAAALALTVVSLKIAGDELRDLADPQGGPEYE</sequence>
</entry>
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    <accession>U1MHG9</accession>
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        </submittedName>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88764.1"/>
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    <dbReference type="EnsemblBacteria" id="ERG88764">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
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            <begin position="93"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="16811" checksum="2C07E3A2178EF63B" modified="2013-11-13" version="1">MSDCPLADECPSFSERIPGMGCQHYGDRGGAEWCNHYNQPIEDLKSQPVKPGEEVVITVEDIHESGAGVGRTDDGFIIMVDGVLPPAQTRVQVTTVHSNHARAEELERLEPEPDDETDDKGGGEGNDETDASENNNDAADSTDPRLGSRDNFWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHT2</accession>
    <name>U1MHT2_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein, beta subunit</fullName>
        </submittedName>
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    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28120" checksum="1BC7964E87BDBA1F" modified="2013-11-13" version="1">MRVLVALSEVTVLDEEFEIAGNAIDERHCTHELNEWDAHALEEAARLAETNDDTEVVTVTVGPERAERTIREGLAKGADRAIRVWDESLDETDLAEPAQKAQLLAGVVNELEPELVIAGTQSSDDTFGATGVALAARAGYEWAAVVNKLELDRADGVAHVRRELEAGMHELTDVALPAVISVHSGINEPRYAGLQEIRRAQKKPIEQYSPAAFGVEPRASRLSLLSLSEPAAAREGARLEGDAEAAADELAGRLSDMEVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHU0</accession>
    <name>U1MHU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR00300 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01030</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88884">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CHP00300"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF04455">
        <property type="entry name" value="Saccharop_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00300">
        <property type="entry name" value="TIGR00300"/>
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    </dbReference>
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        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
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        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="410" mass="43894" checksum="380CAB1A9422FD9B" modified="2013-11-13" version="1">MTATRAVELEGHIIDSGIIETVFDIIMDMGGAFEVETFDIGRSETERSYALLTVKADDSAHLQSIMHELHQNGANPVDPNDAQLQSAPDDQVVPPEFYSTTNHPTDIRYEGEWLTVENPEMDCAVVVEPDGPEGPRAYTEVLNAIEAGDMVVAGNTGIRVRPPERPRGQEGAFGFMQGGISSERPSASTIAKIADAVAETTRDDGNVLVVAGPALIHSGAREGLARLVRAGYVDMLSVGNGFAVHDVERDLYGTSLGMDTETLDHPRKGHKHHIYTISEVIRAGGLEPAVADGTIESGVIYECIEHDADYVIAGSIRDDGPLPDTITDAVEAQSAIREQARRADLVVMLSTLLHSVAVGNCLPSTTRTICVDIDPATVTQLVDRGSAQAVGMVTDVGTFVPMLVDELLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MID1</accession>
    <name>U1MID1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2">
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        <lineage>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="28" mass="2892" checksum="FF96712B55766C72" modified="2013-11-13" version="1" fragment="single">DPTSSPVGPTLGPKADGTPLVDSQNRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIW8</accession>
    <name>U1MIW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01517</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89359">
        <property type="protein sequence ID" value="ERG89359"/>
        <property type="gene ID" value="J07HX5_01517"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490324_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="8913" checksum="D7099BB8975CE4F7" modified="2013-11-13" version="1">MLLAALSLLSPGSFFAGIVVSGLTTIALGLFRVAGLGRDWRGKYALTLAWHQATVAIPTDGTGVIGRTPTFKTATRGATPTPTQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIX6</accession>
    <name>U1MIX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01527</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89369">
        <property type="protein sequence ID" value="ERG89369"/>
        <property type="gene ID" value="J07HX5_01527"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1248256_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="221" mass="23725" checksum="A0B69D0F33599DDA" modified="2013-11-13" version="1">MIEDNSLQTASGASGGAGVLVKNNNSAGNLIALNDIDSEFANGVKIENNANASNVTVRFNNLRGSNAGVRNNDSESVDARSNFWNDKTGPSGDVDDPETGRTADGDGSSIDNGSNGGQVRYDEFLEIPNGFILDTGSPPSGRDTDGDGLHEDFNNDNNHFPTDGYLFLRALRQGHFSRLAEIDQPGGDLSTDYTTRFDFDGDGADDITRKDINEMVINRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ04</accession>
    <name>U1MJ04_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase</fullName>
            <ecNumber evidence="4">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">J07HX5_01567</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89409">
        <property type="protein sequence ID" value="ERG89409"/>
        <property type="gene ID" value="J07HX5_01567"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_1_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="586"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG89409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="780" mass="86112" checksum="60F0CF29D05F9E97" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ09</accession>
    <name>U1MJ09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prolyl oligopeptidase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01572</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89414">
        <property type="protein sequence ID" value="ERG89414"/>
        <property type="gene ID" value="J07HX5_01572"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1417820_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="191" mass="21332" checksum="120FF1FE175CE8DE" modified="2013-11-13" version="1" fragment="single">YDDWGGAEQGDIATGVEHVLEEYDWIDENQIVVYGGSYGGYSTNWQVVQYPELYDAAVTSVGVSDLFDMYENTMPHFQTELMVKNLGDPEENADIYEERSPVEYAENLACPLLIVHGVNDPRVPVSQARILRDELEAAGFTAGEGFEYEELGEEGHGSSDIDQKIRSLELLDDFLDRRIGTQQAPAVSLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ28</accession>
    <name>U1MJ28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagella accessory protein C (FlaC)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01603</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89444">
        <property type="protein sequence ID" value="ERG89444"/>
        <property type="gene ID" value="J07HX5_01603"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1159019_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009205">
        <property type="entry name" value="FlaC_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05377">
        <property type="entry name" value="FlaC_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="239" mass="25627" checksum="D12ED272D0F4257D" modified="2013-11-13" version="1">MAKISDIFNNNHTDDPEDELPADSESSEQSNADPGQTNSENEQPSASPAVLDDTSRADGGAPEVDMEGASTDLNGVEARVTELETQLASTDDELQRVQNAQEDVETSLDEVTETLDELVGMYDQFMADTNPFVDNETAVVHGGATDLIQSGPADEQPTTDDDPSQTAEGDDTAVVETERGADRTDKEERGVKRQPSPVQSQRLCQPSRQTAPTPLIPSLIVLTHSGXXXXXXXGSPPPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ71</accession>
    <name>U1MJ71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01669</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89504">
        <property type="protein sequence ID" value="ERG89504"/>
        <property type="gene ID" value="J07HX5_01669"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="59"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2">
        <location>
            <begin position="154"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="23160" checksum="ADA0BC8B492166C2" modified="2013-11-13" version="1">MRCSPGDSGDGGDDGIGHSHEPVTNRQMTSPPEPGMEQVFAPWRIDWVERDAGTHEGCVFCALPEESDDRQNYLVARGDQAYVLLNNYPYNPGHAMVVPYQHATDHRGFDETVLAGKERLVARTLEAMDAALEPDGYNVGYNLGTGAAGGSVEHLHTHVVPRWGGDTNFMPVIGETSVIVEAVLDTYDRLHAAFAEQAAVAADSDEDAVVVEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJC2</accession>
    <name>U1MJC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01735</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89569">
        <property type="protein sequence ID" value="ERG89569"/>
        <property type="gene ID" value="J07HX5_01735"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968319_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="5939" checksum="DC7F9F26BF8E98FB" modified="2013-11-13" version="1">MEPWKALGLASVTLVAWGGVMTISGYSPGPLTVGAATAFVIGSLYLGDRIGQRIASDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJT3</accession>
    <name>U1MJT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar phosphate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01931</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89759">
        <property type="protein sequence ID" value="ERG89759"/>
        <property type="gene ID" value="J07HX5_01931"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1028975_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="28268" checksum="DB7A96E8F5C20913" modified="2013-11-13" version="1">MLWWSREQTVLAAATMAFFVVMAARLAISPVVPAIATEFQVSTGEIGLALSGMWLSYALMQFPSGLLGDRIGERRVILIAVGGTAVASLFLALSSAFAAFLVWTVVLGAAAGLHFSVAITLLSRRFTNTGAAVGIHNAGAPIAGVIVPVAAALLWELFGWRYAVALGAITAVPAIVLVAAGLPARAPARPDQLLRERVRPGVLFELLARPSIAGTLVMSVLSAFVWQATSSFLPTFLIEHRGYSAPTAGAVFAGYFACSGRWPANNGLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJV4</accession>
    <name>U1MJV4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="18 19">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
                <ecNumber evidence="19">2.7.8.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="19">Cobalamin-5'-phosphate synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="19">Cobalamin synthase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="18">Probable cobalamin biosynthesis protein CobD</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="primary">cobD</name>
        <name evidence="19" type="synonym">cobS</name>
        <name evidence="20" type="ORF">J07HX5_01956</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 18">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="function">
        <text evidence="17 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 18">Cell membrane</location>
            <topology evidence="6 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 18">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 19">Belongs to the CobS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="19"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89784">
        <property type="protein sequence ID" value="ERG89784"/>
        <property type="gene ID" value="J07HX5_01956"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533835_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-1003">Cell membrane</keyword>
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    <keyword evidence="12 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
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            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
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            <end position="316"/>
        </location>
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        </location>
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            <end position="391"/>
        </location>
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        </location>
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            <end position="452"/>
        </location>
    </feature>
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            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
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        </source>
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        <source>
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        </source>
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        </source>
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        </source>
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        <source>
            <dbReference type="EMBL" id="ERG89784.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="510" mass="50642" checksum="7305C7CB8EA9CFCA" modified="2013-11-13" version="1">MLAVWNSDNGDRVEFNGGVPVITGLSFSVASVPTAVGVLVVALALDAAFGEPPERGHPVALFGRVIDRFDREWRFPRVAGVVIGVSGPLAFAVVYAGTVALAGAVGPPALSVVVGGGLLFTTVSLRMLLAVAAETLTAIETDTDRASAQIAALVGRDTTSLTPAEFRSGVVESLAENLSDGFVAPLVAFALGTVVTLPVAVGAAAWIKGVNTLDSMLGYRTNPLGWASARLDDLVMYCPARVTAVLIAVAAGAPAALLAARAWARAPASPNAGWPMATLAGVLSVQLRXXXXXXXPAVFPVAGALIGGIVALPLVLPGPTPTVALAFVAWLYLVTGINHLDGVADLADAAVVHGDAERRTAVMKDTAIGVGGVLGIAVVVVGLALAGLGIANRPPAAVSLVVAAEIGAKAGMGVVACVGSAAHDGLGAALTGESGPSAAGAVLALALPAAAFTWPHPAAAATLVTALVAAGVVLVAAHRLLGGVSGDVFGASNELARLVGLHAGVTVWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK85</accession>
    <name>U1MK85_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Adenylosuccinate lyase</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">J07HX5_02142</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
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        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
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        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
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        <property type="entry name" value="PurB_C"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Lyase_1"/>
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    </dbReference>
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        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
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        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="26"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="2">
        <location>
            <begin position="264"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="402" mass="43463" checksum="FC3DDE0C93207F30" modified="2013-11-13" version="1" fragment="single">ADTFDADDAALVKRIETEGYGDRPATNHDVKAVEYFLRERLPAEVDPAWVHFGLTSADINNLAYRLLLGPAVEEVLGGRLRAIHDRLDSLAERHRDLAMLARTHGQPATPTTLGKELAVYADRLQRQHDRVQSVQLRGKLAGASGSYAAHVAAYPDVDWPAFAQAFVEQLGLVHAPVTTQTNPGDDIATLCAALGGVNGVLLDLAVDAWLYISRDYLGQRSTAGEVGSSTMPHKINPIDFENAEGNLSKATRELGFLSESLVRSRLQRDLSDSTVKRTIGATLAHCLLGYEKLADGLGSVTPNEAVIAADLEAHPEVLGEAIQTILRREGDPEAYEAIRTATRDRSVSLAQLQSVIADLDVSEPVRAELQSLSPAAYTGVAADLVDTRSNHDADQEHDQSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV45</accession>
    <name>U1MV45_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00091</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87950.1"/>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00091"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1485844_0_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="19382" checksum="12987A76D2C87504" modified="2013-11-13" version="1">MGCRSGCPLTAGLRYCNPSLPPILRRTPSSHPRSCSSGRPPHADTPGNRKSAPAPGRRWHRYRRLPANGAQRYSLVPHAGSTLVLELACESGTAVPTSETLADGDSGNPLGSRRTANSRWRVTSDESSRARSVRGVHARSGLAVSVRDPAVRSQAARSAEQGPERRSAVPALGRPRHASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV76</accession>
    <name>U1MV76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UV damage repair endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00136</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87995">
        <property type="protein sequence ID" value="ERG87995"/>
        <property type="gene ID" value="J07HX5_00136"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="PTHR31290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="14833" checksum="118438ED93A77610" modified="2013-11-13" version="1">MALGYPCMNRTLREGTPVRCNRSMQKQTWERDGLPYASELTLQNFQDLERILEWNVAHEIGFYRCTSELVPWHSQYELEALPDFPAIETAAQRCGELIDXXXXXXXXPSWRAAYSAVLLPVREPTGRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVA6</accession>
    <name>U1MVA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine-uridine nucleoside N-ribohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00171</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88030">
        <property type="protein sequence ID" value="ERG88030"/>
        <property type="gene ID" value="J07HX5_00171"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036838_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015910">
        <property type="entry name" value="I/U_nuclsd_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01247">
        <property type="entry name" value="IUNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="3">
        <location>
            <begin position="38"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="351" mass="37798" checksum="7583DA65A99BC21B" modified="2013-11-13" version="1">MSREVEQYYSVGSSCALPKIIVRQTMIGLYNSSMATDIILDCDPGHDDAIAALLALGAPELSVQAITTVAGNQTLGKTTRNAQQVLTLAERTEVPVASGMATPMVRDLTVAADVHGDSGLDGPELPDPDPAAEAVEEHAIEYIAQIARETDGLTLVPTGPLTNIGMLLRRYPDIVDQIDEIVLMGGAIGLGNYTPAAEFNILVDPEAADLVFRSAVPVTMIGLDVTRNALIRRAEFSRFRALDTTVGVTVAGWLEYFTQWYDQQFELDGVPIHDACAVAMLIDAGLIETEQMHVAVETAGDHTAGRTVCDRHGVRDAAQSETQAQPRNTRVGVDIDREPFLELLVDAVARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVE9</accession>
    <name>U1MVE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00079</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87938">
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        <property type="gene ID" value="J07HX5_00079"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3145864_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5234" checksum="46B241E246D7EF17" modified="2013-11-13" version="1" fragment="single">GDSLAYDVAGAHNAGLSVAWLQDGGRPEPYEPDHMLESIGELKPLLVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVG7</accession>
    <name>U1MVG7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00099</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87958">
        <property type="protein sequence ID" value="ERG87958"/>
        <property type="gene ID" value="J07HX5_00099"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127455_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20538" checksum="7EE248FE7D11104B" modified="2013-11-13" version="1">MIDDWIATIHPDDVPTNGTNDAGVPWSQIRPLWLTFCGFDTPSARGGHVNMSPSELDSWGTHECADKKSLEPQQVRDRVRKAATTHPQQWESYGDKGNDDPTTMGHVEIAKKVNAFNARGYGSWKAYGEYKSFGTTTCPSGWGIANLNWQQDPQRLYATEYYDVHTAARDRYVEIRRELQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVG8</accession>
    <name>U1MVG8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00248</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88105">
        <property type="protein sequence ID" value="ERG88105"/>
        <property type="gene ID" value="J07HX5_00248"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12266" checksum="544C2D3025E3C896" modified="2013-11-13" version="1">MTENAKTEAPSEPIALGGSNEFGSVVQAHEVVIVDFYAEWCGPCKMMEPAVESIAADTPAAVLKVDIDQHQQLASEHNVRGVPTTKVYAGGDEVDQMVGLQSEEELAAAVEQHGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVU7</accession>
    <name>U1MVU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00240</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88098">
        <property type="protein sequence ID" value="ERG88098"/>
        <property type="gene ID" value="J07HX5_00240"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="324" mass="35449" checksum="EAEE250BF5599E27" modified="2013-11-13" version="1">MQDALVIGGTRFIGRHLVRELLAHEYSLTLFNRGRHENPFAGNDRVGQFTGDRTSDAALTEAREAVDPDIVIDCVAYHPGEVQMATRVFEDVTAYVFVSSGSAYGAEEIPKREDETPLASCTNEQAIDNGPETYGNRKAESDRAVFEAAAAGGNAMSVRPTIVYGPHDYTGRLRYWVNRIREYDRVLVPGDGTNIHHLVGVESVARAIRTVAEAGTPGEAYNVADRRVLTLQGVLKRIAAAVDRDPQLVYANPRALEQHGVDPTVFPLYNPQPHILTTEKLFELGWEPVAPDAAITEAATAGYEPDRNPGPDRSKTAALIEDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW26</accession>
    <name>U1MW26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00469</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88325">
        <property type="protein sequence ID" value="ERG88325"/>
        <property type="gene ID" value="J07HX5_00469"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="48"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="306" mass="33245" checksum="873255BE1860CA6C" modified="2013-11-13" version="1" fragment="single">MAGGVMLSAGKNTYRDSFMHRVIAERPFAETDTSVKTAIALYEGLIRTRRFDERALSLQRRGWMSSYPSFQGQEASQVGAASALATTDWLFPTYRSNALQIARGVPMSDILLFRRGHPEFASGHDVPVFPQAVPIATQLPHAVGAGMAATYRGADHAVLAYLGDGATSEGDFHEALNFAGVFNAPVVFFCENNGWAISMPRTQQTASATLAQKADAYGFDGVRVDGMDPIAVQQVVSDALADARDGAPVLVESLTYRQGAHTTSDDPSRYNDRGPDLPEWRTSDPIERFETYLSEAGVLDDDRVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW76</accession>
    <name>U1MW76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00381</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88238">
        <property type="protein sequence ID" value="ERG88238"/>
        <property type="gene ID" value="J07HX5_00381"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3280813_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="3908" checksum="DE06CD256CC3C92A" modified="2013-11-13" version="1" fragment="single">MDRTRRQLLAGLGTAGGAAVAGCTSFLPGVGGGADGQFALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWF0</accession>
    <name>U1MWF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00590</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88445">
        <property type="protein sequence ID" value="ERG88445"/>
        <property type="gene ID" value="J07HX5_00590"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2820650_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7606" checksum="462DF3BAA45C73F6" modified="2013-11-13" version="1">MKYNHVRRFLALVNKWCPRCYRHELPSLTAWNSGSLIKSVLGRAVGLRQRDLLQTVTPATQRAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWK0</accession>
    <name>U1MWK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00661</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88515">
        <property type="protein sequence ID" value="ERG88515"/>
        <property type="gene ID" value="J07HX5_00661"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="17"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="476" mass="54201" checksum="E5BFBF138ED738EF" modified="2013-11-13" version="1">MSSTQDSSSSETAAITDPTLFWHQRGLRVQDNAGLAAAARDGTVVPVYVYDPRAFKMVGPRQRAFVLAGVRELKQQYRSLGSDLIVRAGRPSEVLPDLAAEHGADNIYYNEHYRPARRNSQHRLERETTDCSVASRTDTLLVDPGRLESSYANHSQFYNDWQDVPKRPPFEAPSEDSLAAISDSKTVPEAETEIELPAAGYQAARDRLDAFCADGIFSYNDTRDDLPRAVEAPTQAVSRLSPYLAAEMIGIREVWAAANDAYGQATGRERKNVDKYRYELSWREQNYHLLYYNPQLASENYKQFPSEIAWRDDDEAFAAWTAGETGYPLVDAGMRQLEQEGYIHNRPRQVVASFLTKHLLVDWRKGARYFTKQLIDHDHASNYGNWQWTASTGTDSVDVRIFDPVSQMSKYDDEAVFVTEYVPELRDVPARKIVDWPTLSRGERERLAPEYPHPIVNRNDGYERAQRVFEQALGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX10</accession>
    <name>U1MX10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative P-loop ATPase/GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00664</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88518">
        <property type="protein sequence ID" value="ERG88518"/>
        <property type="gene ID" value="J07HX5_00664"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_923186_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="28753" checksum="0A0D5909724DE20B" modified="2013-11-13" version="1">MTLLVVGADRVDAGKTTFTTGLIAYTDAVGFKPRAGNDWWFHHDDCHTALDASSLYGADARKIVAAAPGDLAPEMINPVHRLWRPAPAPGPGLLGQDGQEFLLDRAGDRYVLNGQATLPSRLSEQLPLANAVVVESVAELNAAIEQLHLPALDALKRTIKTTDRAVVESYGDVARPVQGLAPTAVAVVEPKRVRVYDGHRYGQACQVATGASSPLEGQLEESVSAVTELIDPATTVETMPLRAATRAEPAAIADAYERVYRRVLDVAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX15</accession>
    <name>U1MX15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rad3-related DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00669</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88523">
        <property type="protein sequence ID" value="ERG88523"/>
        <property type="gene ID" value="J07HX5_00669"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022234_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="DEAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042493">
        <property type="entry name" value="XPD_DNA_FeS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="561" mass="62617" checksum="77FB66B363358C54" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX77</accession>
    <name>U1MX77_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="4">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">surE</name>
        <name evidence="6" type="ORF">J07HX5_00896</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88750">
        <property type="protein sequence ID" value="ERG88750"/>
        <property type="gene ID" value="J07HX5_00896"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045192_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="5">
        <location>
            <begin position="6"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="260" mass="27101" checksum="60C923668F968ACF" modified="2013-11-13" version="1">MYDPKILLTNDDGIDAAGHRALYDALSEIGAVTAIAPATDQSAVGRTLSYSARVREHELGYEIDGTPSDCVIAGLSELVPDVDLVVAGCNRGANLGTAVLGRSGTVSAAVEATFFNVPAVAVSTYVPTGEYTSGDKLALPRDQYGEAVSAAAFLINNAELGELFGNADYLNLNAPVSDDARSEMTVTVPSRSYHMTATRVGDEIELQNNAWGLMSDGTLSDEPGTDRQAILDGLTSVSPLTAPHTVEEAAALGTLTEAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXB4</accession>
    <name>U1MXB4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD kinase</fullName>
            <ecNumber evidence="8">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nadK</name>
        <name evidence="9" type="ORF">J07HX5_00779</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88633">
        <property type="protein sequence ID" value="ERG88633"/>
        <property type="gene ID" value="J07HX5_00779"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_480320_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="6 8" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="133"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="555" mass="59447" checksum="6139409069B7CA51" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXF3</accession>
    <name>U1MXF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dinuclear metal center protein, YbgI/SA1388 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00971</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88825">
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        <property type="gene ID" value="J07HX5_00971"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037423_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
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        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="26312" checksum="BC67A4CA926BA2EA" modified="2013-11-13" version="1">MDCQTLCARLDAELKTDAYAAVDASANGLQVGTTTGEVERAAFAVDAAAETIERATAANADILIVHHGLSWGGIERVTGQTYDRIATLVDADIPLYVSHLPLDGHPDLGNAAGVADVLGLEQRDPFGAVGDEYAGQQGVLPAPTDIAGLREQLTPALDTGEGAVQTLAFGPNSIERVAVLTGSGADWLDAAVTAGADVLVTGEGKQKLYHQAREAGIHVLLGGHYATETFGVRSLASLVADWGVETTVIDCPTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXT2</accession>
    <name>U1MXT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate dehydrogenase/fumarate reductase, cytochrome b subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00964</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88818">
        <property type="protein sequence ID" value="ERG88818"/>
        <property type="gene ID" value="J07HX5_00964"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127125_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045281">
        <property type="term" value="C:succinate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039023">
        <property type="entry name" value="SdhC_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41910">
        <property type="entry name" value="PTHR41910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11000" checksum="9F6A64924FE92FCD" modified="2013-11-13" version="1">MLLGYLFTHIAVLSTAIGVDPTAATAGADQYTEILRGLEELLVVRVLEIRVVAAATFHLLNGVRLLLVEMSVGISVQDKSFYGSLVAASITTLVSVPVFLAGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY09</accession>
    <name>U1MY09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01201</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89050">
        <property type="protein sequence ID" value="ERG89050"/>
        <property type="gene ID" value="J07HX5_01201"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3280814_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4644" checksum="F49E0C421DE0D1B7" modified="2013-11-13" version="1" fragment="single">MANFRPHSPQRASLAPSLTDENNQLTSERYSEWALTSIPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY22</accession>
    <name>U1MY22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01217</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89065">
        <property type="protein sequence ID" value="ERG89065"/>
        <property type="gene ID" value="J07HX5_01217"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152338_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046243">
        <property type="entry name" value="DUF6276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19792">
        <property type="entry name" value="DUF6276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="140" mass="14673" checksum="6954BCE073692E1D" modified="2013-11-13" version="1">MSPPDCRRCAAATIAIDAGEYAETVPAETTRLVLCTHCLALESAPTDGADTPTTAGADHEPAVAQVSEQFPTGEAAVPFALLVGLLENLALNRAAITDLLAAVEHAGVDPLARLEQLTHDPEIEPAIDLEGRARQLEQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYH2</accession>
    <name>U1MYH2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01225</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89073">
        <property type="protein sequence ID" value="ERG89073"/>
        <property type="gene ID" value="J07HX5_01225"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026762_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="438"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="529" mass="56782" checksum="B61F198424011469" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYH8</accession>
    <name>U1MYH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01380</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89225">
        <property type="protein sequence ID" value="ERG89225"/>
        <property type="gene ID" value="J07HX5_01380"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_553921_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="492" mass="53012" checksum="AED684EB25712A92" modified="2013-11-13" version="1">MHCRHCRVLFGALVLLAAVGLAGCSGLSGPDGDNSPDASENTERPPQAGIDRPTFETVTAALDAEQTTAFRAAVTAGGQLTDRGERLLAGLAELAPASRRVVAQAVTDRGAVTERAVAAVERVQPAPPAFQQAAFARGLTDTTGGGVLDGERLALGFDPDGYKPQVDELIRSLGADGYSERDLAYLRTVGNLSWVEWRQAEQLRLLHEAVTDGVVPQTTVAALQDESGDGLVNGTAEAFGLNKSVQHDGVAELVVSLAFNGITTTEWQYLDQAAAQSQTPFTWTQAETFVYRDVADNRVTASDRSRLTDTSGDGLLDGFIERLGADPTRSHDRLRPYAEELATPFDLYTFNDIQYLGRLAQLSTDEHLWAQATSFGLLGQELIRRGFVTLPDRQELRETVPGVLNATAAAIGLTERPAATETVRTLLQSLVEGPDDSYTETEIAYLKRAVELSQYRGTSTSAGPRPTARTAXXXXXXXXVTSRRLQFELLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYI2</accession>
    <name>U1MYI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cellulase M related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01235</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="MEROPS" id="M42.005"/>
    <dbReference type="EnsemblBacteria" id="ERG89083">
        <property type="protein sequence ID" value="ERG89083"/>
        <property type="gene ID" value="J07HX5_01235"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047249_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="340" mass="35524" checksum="CD5D6D8C86568D12" modified="2013-11-13" version="1" fragment="single">ETLLQTDTPSGYETPGQQAWIEYVSQYADTVRTDEYGNAVAVLEGGQPTVAIGGHADEIGLIVRDIDEQGYLRVSPIGGADKTVSKGQHVVVHTADGQLPGVIGQTAIHIREDDEPTAIGDQFVDIGAEDQAAAAELVDRGDPITFTQQMADLHDGKLSARGLDNRVGIWVAAEALRRAAAADPTATVYAISTVQEEVGGRGAEMVGFDLAPDAVVAVDVNHATDTPGGAGKHTNGVELGGGPVISRGGSNHPRLGQAVRTVAEAESIDVQLQATGGRTGTDADSFFTQRGGIPSLSVGVPNRYMHTPVETIHLEDLETVAALMGAWAGRAATFEYRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYN7</accession>
    <name>U1MYN7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-alanine-DL-glutamate epimerase related enzymes of enolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01442</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89285">
        <property type="protein sequence ID" value="ERG89285"/>
        <property type="gene ID" value="J07HX5_01442"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="149"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="390" mass="43410" checksum="0383CD7F76FA48EA" modified="2013-11-13" version="1">MPPQITRIESIEFAYPLTDVGTDDNGFNLVYEPGTTTERKLFAVRIETDDGITGTYVGGNSPAAAQYNTVAGYLIGKSALKRERHWSEIKRALRKYDRMGIGPIDIALWDLAGKHYDAPLHELLGTYRERLPAYASTYHADDNGGLDTPEAYADFAEQCLKTGYGGFKIHGWGGSDDRRSVEREIATIHAVGERVGDRMDLMTDPACELETFGDALRVGRACDEQGFFWYEDPYRDGGISQHAHRKLRQQIETPLLQTEHIRGLEPHTDFIENEATDFVRADPEYDGGITGAMKIARVAEGFGLDVEFHAPGPAQRHCIAATRNANYYEMALLHPDCQNTGPPVYEGDYSDTIDAVDDNGTVPVPDDPGLGVSYDWEYIEANQTGKRVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYS6</accession>
    <name>U1MYS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01483</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89325">
        <property type="protein sequence ID" value="ERG89325"/>
        <property type="gene ID" value="J07HX5_01483"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3385903_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3574" checksum="A7795377E76B4E5F" modified="2013-11-13" version="1" fragment="single">MTTVQCCQCGSALDRPGDYCLVCHTTNADRVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYU2</accession>
    <name>U1MYU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01357</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89203">
        <property type="protein sequence ID" value="ERG89203"/>
        <property type="gene ID" value="J07HX5_01357"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_948660_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="293" mass="32675" checksum="98D84AAA960CBFDB" modified="2013-11-13" version="1">MRDRSRRKFLALLSATGIAGAFGVGSASAVDSARPEGIETFAASGKQIRRTKIHPEQVEVTQTVVSQDLDSRYGKKRVRFRDVAERAEPATDSLPQEDVRVQQGSWTGYYATEEDWQRLYDEGQRDAPVSGTEPAPSYATYEYKKDTDGGFAIAAPMNVLSKESIGPIRNVAIDHHYTNYVAQFDRYAFNTDETEFQTQHCSIAESPLRVFGGAHARLWEFGGWTSISAHVDSDVLAHSAISFLDAERDLESVFDDADGWDGVRDYKHLDNEQYLPEDAPDDHNGDATELVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYV5</accession>
    <name>U1MYV5_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01373</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89218">
        <property type="protein sequence ID" value="ERG89218"/>
        <property type="gene ID" value="J07HX5_01373"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1623409_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="17948" checksum="6F3055C5767CA34D" modified="2013-11-13" version="1">MNAASDLSVDTIERRDGSPPRDRLAAGQAETDADHTADDDANAQDAPEDLTPASANQEPVAVRERKAEISGLETLTRQMLSVYYTDGPMKPTEVHAAAGGDGDRKRSYARNRALRTRGLINHVGQGYYDDRLRAVLREDDGLAEHNRIDQHLQEIERVALGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYW8</accession>
    <name>U1MYW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exoribonuclease R</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01388</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89233">
        <property type="protein sequence ID" value="ERG89233"/>
        <property type="gene ID" value="J07HX5_01388"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982130_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="70"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="283" mass="32180" checksum="33436A757E7ED377" modified="2013-11-13" version="1">MSDSQAAQGTPEGQGPVEVSEELARHLANKRDELFEKFEIPDAFPDEVQQEARRRSQNVAEEIEAELDDRRDLRELTTWTTDPVDAQDFDDALSVETREDEYVLWVHIADVTHYVAPDTAMWEAAQRRANTVYLPGYTVHMLPPVLAETVCSLVPHEDRLAHTVEMHLAKDDLSYETIDIYKSVINSDARLTYTESEQILEEPEAAAAHLPADETGDLDEKVALVWELTDEMHEQRKADGSLVLNPRRDRAHTIIEESMLKANKAVTHELMWDXXXXXXXPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ72</accession>
    <name>U1MZ72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dihydroorotate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01651</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89490">
        <property type="protein sequence ID" value="ERG89490"/>
        <property type="gene ID" value="J07HX5_01651"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013640_3_0_2"/>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="6">
        <location>
            <begin position="51"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="20437" checksum="7F890AE86C927AF8" modified="2013-11-13" version="1">MTVYERLRPLLFRLSPEHAHRFSQTAFKFIQETSFRRGFEAALSVSDGRFTTTVLDRQFPNPVSVAVGYNRCAEVPHRLSALGFGFVKVGGVTAQPQGGNPRPRLFCLSEDHGLITRLGLNNDGAAVVGKRVAAADTQVPIGVTLAKGEAVPLEAAAADYRQGYKAVTAGDFSGERLVPELPGVRDAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZA7</accession>
    <name>U1MZA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01521</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89363">
        <property type="protein sequence ID" value="ERG89363"/>
        <property type="gene ID" value="J07HX5_01521"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2140125_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="11880" checksum="4089433909E5526B" modified="2013-11-13" version="1">MCRARALTALFDTASAGIVFARTLDGFAVVSGGAVAVDVVDAPKIVADGTDSAVAGSSDIDDVDRLDTSLSYIPWRTAISALSLPVTRRRYRLIGIGFFNSPRDTIPAQRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZG4</accession>
    <name>U1MZG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NTP pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01766</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89600">
        <property type="protein sequence ID" value="ERG89600"/>
        <property type="gene ID" value="J07HX5_01766"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040940_5_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="21542" checksum="12FB84CDF1B9B5A6" modified="2013-11-13" version="1">MELDLDCVHRYDPESVTTGRPASVVVPIVDAGPALLFTKRAEDLADHPGQMSFPGGRQEPADDHRRATAEREADEEVGLSADELAVVGRLDDIMTVTDFAVRPFVARIPDREYAPASREVAAVTTLSVTALCDPTNYTARVHDGRHVDYFTVDGHTVWGATARILVGLLALTTDWERPEQPATSSSDAEPEPGSGPGPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZK9</accession>
    <name>U1MZK9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01644</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89483">
        <property type="protein sequence ID" value="ERG89483"/>
        <property type="gene ID" value="J07HX5_01644"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032621_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="394" mass="43219" checksum="EA28D8BC1ABC444C" modified="2013-11-13" version="1" fragment="single">MTNVGGDDQVDRPSNQTPRTDGGTKSDNVSLNPWGSATVSDYRKLFKQFGIQEFETILGDVPNPHYLMRRGVIFGHRGYDAVAAAMRNDEPFAALSGFMPTGDPHIGHKLVFDELIWHQQQGGDVYGLIADLEAHAARELSWGEIDDHARDYVLSLLALGFDPDAGELYRQSTNRAVQDLGFELGAEANFSELRAIYDFDGETDVSHMQSVVTQMADILYPQLEEPKPTVIPVGPDQDPHVRLARDLAARVRYFGVTEAYASFEAGPAEQAIIADAYERLREQTPTDEQVRCVEAADLLAGGSATAPDRSLTSAGSEADQAHERAVSLLREAGKEPLRPRVRFVDRNATGAAFTGLIEAIDGEKRVYEEHIDAFELEQSAAETLARTVELDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZL1</accession>
    <name>U1MZL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01815</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89645">
        <property type="protein sequence ID" value="ERG89645"/>
        <property type="gene ID" value="J07HX5_01815"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353158_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="10021" checksum="6319AF3C578FE451" modified="2013-11-13" version="1">MNKHFEDMRYYLKRAGETAKRGIAEELEPVQDQVQALVGEDEEPEPSRIEQLRDDLNELGERAEGEAKEAIEEARGKLDNYRGEQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZN3</accession>
    <name>U1MZN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenite-activated ATPase ArsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01673</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89508">
        <property type="protein sequence ID" value="ERG89508"/>
        <property type="gene ID" value="J07HX5_01673"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1149227_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="26054" checksum="B84DB373DF1F0E41" modified="2013-11-13" version="1" fragment="single">EPLAGLLGGETAAAMPGADEAAAVWLLLEYLDDPRFDRVVVDTAPTGHTLRLLKLPEMLDSLTDQLSGLGEQLGEAGPFGDMGAGAGVGGGATVGGTVADSPGGIEGLEQFGTQIQRLRTRLQDPTRTDFRIVLVPEELSVAESERLRDRLNSFGIPVQTVVVNRVLQDPAAVADVDPDWFVAPDHTDCAFCARRWEVQQRALKRAQELFRDHAVRRVPLFAEEVHGERLLRVVAACLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZS2</accession>
    <name>U1MZS2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01724</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89558">
        <property type="protein sequence ID" value="ERG89558"/>
        <property type="gene ID" value="J07HX5_01724"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029030_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016602">
        <property type="entry name" value="UCP012666"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012666">
        <property type="entry name" value="UCP012666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="452" mass="50503" checksum="0121C8A044E98ADA" modified="2013-11-13" version="1" fragment="single">LYAVDSRTDALQRVPRQLLGLIGFEKELGLHNAEMQTSPQPLTGHGLDAQENELKAHLAPALEKTATAQIRLVSDGLWTVPPTGETAADYLTDTVKHNGTTIAANMSDSVRYHTMANTDYPAGCCIQAPNVTLDAETLMPESMITSIQPHYQVAHAPDLAERFRYALRVAGPLLALGVNSPFFPPELYDDVPADEILANAHMENRIHVFESVMNPPADSDEPPKVRFPPDFETVEDAIDDIATDTTIVPQAVTESNRFDDALLHLLHKHGSYWRWVRPVFEAPSRSAANARIEFRPLPSQPTVLDSVAFEAVFAGLMESLPRREHPVRRLSWSQAESNFYAAVRDGLDARIEWITADGSETTAIEEICGECLEFARDGLELRGLSTQKARRYIRPLRERLDRRTTPASWKQTRVRDQVNDGAPLTEAIWGMQSQYIDAQRETLIEGSFVDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZY0</accession>
    <name>U1MZY0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor 6</fullName>
            <shortName evidence="3">aIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">eif6</name>
        <name evidence="4" type="ORF">J07HX5_01937</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eIF-6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89765">
        <property type="protein sequence ID" value="ERG89765"/>
        <property type="gene ID" value="J07HX5_01937"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071894_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="PTHR10784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="222" mass="22713" checksum="07BFC82B4D9732E6" modified="2013-11-13" version="1">MLRVAFSGSPYVGVFARATDDCLFVRPDLDTDRTEQLGAELGVTPVETTVGGAGTAGALAAGNGHGLILSNRLRDRERDRIADAVDGPVTELPGRINAAGNVVLANDTGAYVHPELSREAVQAVKTGLDVSVQRGAIAGVHTVGTAAVATNRGVLCHPKTDDETLDELEDVLGVPADIGTINYGGPLVGSGLIANDTGYVVGERTTGPELGRIDAALGYAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N001</accession>
    <name>U1N001_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP:adenosylcobinamide-phosphate guanylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01957</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89785">
        <property type="protein sequence ID" value="ERG89785"/>
        <property type="gene ID" value="J07HX5_01957"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098907_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="19778" checksum="CD776B2BF6E8B8F3" modified="2013-11-13" version="1">MCGGQGRRLDAAVEKPLFEVGNQPMIDYVLGALADSALGPVRAVTSPQAPATQAHLNEQGIACVEAPGEGYVADLSYALDDVSTPALTVAADLPLLEPAVIDRVLAAYDGDSVAVYVPAAVKTALGVSYDRTAVCAGRPAVPAGINLVAGADERPHLSHDVRCAVNVNRQCDAAVAETLACADADGDAPAGGSDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0G0</accession>
    <name>U1N0G0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01980</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89808">
        <property type="protein sequence ID" value="ERG89808"/>
        <property type="gene ID" value="J07HX5_01980"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1986102_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="126" mass="13497" checksum="5DD467C392605682" modified="2013-11-13" version="1" fragment="single">MKRRSILKSMTIGTMGVTAAGTATADNKPGRVKPEHEVPEHAEIRGQYAELTDIDNTDTSTNRLVSALHADGLVSDPELTKLSAISDGANTIEQSSHVDLMSTVDTKPETPTAVIRVSDKHSETQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0I8</accession>
    <name>U1N0I8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02138</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89965">
        <property type="protein sequence ID" value="ERG89965"/>
        <property type="gene ID" value="J07HX5_02138"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3054603_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="53" mass="5205" checksum="390FB313CC88FDA2" modified="2013-11-13" version="1" fragment="single">TTDPRYVLVGMAVGLIFGVAVGAELNSLAESITLGMGTGVSIGIALGTTAHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3V4</accession>
    <name>U1P3V4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit III</fullName>
            <shortName evidence="5">FGAR amidotransferase III</shortName>
            <shortName evidence="5">FGAR-AT III</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purS</name>
        <name evidence="7" type="ORF">J07HX5_00340</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PurS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88197">
        <property type="protein sequence ID" value="ERG88197"/>
        <property type="gene ID" value="J07HX5_00340"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164833_3_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01926">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9072" checksum="E8025042ADC0ADC3" modified="2013-11-13" version="1">MTAYTATVTVRPKGSVRDPEAETTRRALTRLGFELEAITTADQFALELAADSAADATERATEMAERLLANPTVHEYTVEVTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3V9</accession>
    <name>U1P3V9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Choline dehydrogenase related flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00345</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="228"/>
        </location>
    </feature>
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            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
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        <location>
            <position position="530"/>
        </location>
    </feature>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="530" mass="57354" checksum="AF10935304F2A508" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
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                <person name="Narasingarao P."/>
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            <begin position="45"/>
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        </location>
    </feature>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="192" mass="20819" checksum="C5AB68C7654F6C5D" modified="2013-11-13" version="1">MSESTHRAPTTASEPLLEVEDLRTVFRTGTETVHAVDGVSFDIYPGETVGLVGESGSGKSVTARSILGLVDTPGRIENGTIRFRGEDLVQTGWEDHRGDIAIVFQDPLNSINPVYTIGNQIREALRIHQGLTGADARSRAVELLTAVGIPDAQRRVDEYPHQFSGGMQQRAIIAIALAVTRICSFVTSRRPP</sequence>
</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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    </dbReference>
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            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9498" checksum="640EFFFDB00CAC5C" modified="2013-11-13" version="1">MVDIEAFNIAGVVQYSMGKTCQLQVRRLAGVMTILGLTLGIVVSQWFFLLIGFVGANLLQSSFTDVCPAEELLPGCETSDEEGSAVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4E7</accession>
    <name>U1P4E7_9EURY</name>
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        <submittedName>
            <fullName evidence="9">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
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        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UBIAD1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="321" mass="33001" checksum="D101703723F99E01" modified="2013-11-13" version="1">MLRAWVIKRRPKLWVLWAASRPDQLLLIGLLYTLGIGMATAGSPIVAGDATHLVQDGTLDTALVSQIFVGALGLIAATLAIHYANEFADADTDALTDRTPFSGGSGALVETGLPAASLRRPLAVACTLTVVVALGGVVTAGLPPDAAGLLLVALAVGVGYSLPPVALVRRGYGEPTNMLLGGLVLPVYGISVVASPRPAAALAVVPFTLLVGCNLLAVHWPDRNADAAVGKQTLAVRWPPARLRQAFAVLAAGAGASTAGLWLTETVPSAVAVAHLVPVPLLVWGWTTLTRDQSPLPAVAAMVVLAVTTTVAWWWVGVGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4U9</accession>
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        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">J07HX5_00698</name>
    </gene>
    <organism evidence="2">
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88552.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88552">
        <property type="protein sequence ID" value="ERG88552"/>
        <property type="gene ID" value="J07HX5_00698"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1307110_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="210" mass="23872" checksum="AB421BD664B6F332" modified="2013-11-13" version="1" fragment="single">RLRLERFDKVVDPQLMYRHASRRHSATIDEETTYVTWSPHAHANESASVIDQFRDAWEARESATYAVVPGADEEDAGAFAGNTGVGFKWERQMAGLGIWLRKPFWGRRYSGERAEGLATLAFERLGVEMLAVTVVPANENSIRAVDRYIDRLGGRREGRLRNYATTQDGEVYDVVRFTLSRDEFLQRASKPSVTMRETLDESQLATSDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P524</accession>
    <name>U1P524_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytoene/squalene synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00788</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88642">
        <property type="protein sequence ID" value="ERG88642"/>
        <property type="gene ID" value="J07HX5_00788"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257253_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="PTHR11626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11290" checksum="252485307E05F155" modified="2013-11-13" version="1">MANSDSTSFRAVQAEPDLAWCYDAVQDVSRTFALTVDVLEEPMASHIALGYLLCRIPDTVEDAAHIPPESQAELLREYERSRSSVAGDRRVVPRGGRSVAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P579</accession>
    <name>U1P579_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00848</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88702">
        <property type="protein sequence ID" value="ERG88702"/>
        <property type="gene ID" value="J07HX5_00848"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1559417_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18458" checksum="F76B3FD37AB86C2A" modified="2013-11-13" version="1">MGGTADVRPSLLLVIGAYCASGVLSVGSVMRVRRRQRRQCRVLCLPSRGLFNHCLALSEGTPSILIAAMLACVIYRGAGRVLRGRTEDGVFRNDERRCLSNHLTPRYFTRLASRCCVFSPLLTTCRTGAPTPPGRPPTDSAAVCRLLFAPPSSPCRRTRRAAVTPVAGCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5B9</accession>
    <name>U1P5B9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH:ubiquinone oxidoreductase subunit 3 (Chain A)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00883</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88737">
        <property type="protein sequence ID" value="ERG88737"/>
        <property type="gene ID" value="J07HX5_00883"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119549_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000440">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038430">
        <property type="entry name" value="NDAH_ubi_oxred_su3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11058">
        <property type="entry name" value="PTHR11058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00507">
        <property type="entry name" value="Oxidored_q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="14555" checksum="4351212CE8B826F2" modified="2013-11-13" version="1">MSDWIAVGAMAVVAAFVTGGMISTSWLLRPNVPEQGKRAPYESGEVPTGSARAVQFNVQYYLVALVFVVFAVEIAFIIPWAVVFETAVIEVGLVRVAAPMAVFLAVLVAGLGWAWQAGALEWRTQPTPSRTETDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5S8</accession>
    <name>U1P5S8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01013</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88867">
        <property type="protein sequence ID" value="ERG88867"/>
        <property type="gene ID" value="J07HX5_01013"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754625_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15349" checksum="5319584B0DB010D1" modified="2013-11-13" version="1">MTDNGTNRRQILKHAGLAGAAAAGASAGCSAFGGERPTRASGRGATGLVLHNMTDETQQISVTATNDDPEPNIDKVPIDGTFLIDPHSVNRPETEGPLVFDATVQFEVSVDGGPEGTAEWVAHGGGAHIILTPEEDVLFAETFGVARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5W0</accession>
    <name>U1P5W0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nicotinate-nucleotide pyrophosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01058</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88912">
        <property type="protein sequence ID" value="ERG88912"/>
        <property type="gene ID" value="J07HX5_01058"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="6">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="5">
        <location>
            <begin position="100"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="19631" checksum="0871C9EF36BFFEA5" modified="2013-11-13" version="1">MLTQTQIERWLQADLGHHDVTNDLPGDTTGRLVAGASGVAAGLEAAARVFEYLGCTATCEAAAGDAVESGETVLRASGPTRAVLRGERVATNVVSHASGVATRTHRAVTAATAAAPAVRVAATRKTTPGLRGLEKRAVAAAGGDTHRLNLSRLSSSKTIISPSSGSRRRPSGSATASRSLRPSRWRLNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P676</accession>
    <name>U1P676_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01208</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89057">
        <property type="protein sequence ID" value="ERG89057"/>
        <property type="gene ID" value="J07HX5_01208"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3038914_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="54" mass="6011" checksum="50135A4CB3E20D6A" modified="2013-11-13" version="1">MLGLSSTVKIINTSVVSFVSRVNSFAFVSEYCDDRPVYRKRGQLVELLQCVPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P688</accession>
    <name>U1P688_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01224</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89072">
        <property type="protein sequence ID" value="ERG89072"/>
        <property type="gene ID" value="J07HX5_01224"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079542_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="245" mass="26613" checksum="F2772F439C4750B1" modified="2013-11-13" version="1">MSVEIARAIDIAITDEIDHVPAVAGIADRSEADAMEAYLSLAAESGYDRSRVQEIGEALDYATHWLRYNTGREFVYELLNVNCDSRARHDAVVDLLAERASDDVDRQLAAAEEHVVHEQLANDAHLYRIDVDEYAKRFTYPAPGKTTGKVHDQKVAETGDPVITIGYGPDFAVLRSDXXXXXXXAMVTELKTEIDGGGVSGGGHLVVGSIQFVRGMRGTVLEALIEKMADAEIDETLGSSAVVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6L1</accession>
    <name>U1P6L1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl11</name>
        <name evidence="9" type="ORF">J07HX5_01366</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89212">
        <property type="protein sequence ID" value="ERG89212"/>
        <property type="gene ID" value="J07HX5_01366"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="7">
        <location>
            <begin position="68"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="162" mass="17144" checksum="CC18A4FC1D78BE94" modified="2013-11-13" version="1">MANTIEVLVPGGEVDPGPPLGPELGPTPVDVQTVVADINDQTAAFDGTEVPVTVEYEDDGSYEIAVGVPPTAELIKDEAGFETGSGEPQEEFVADVSVEQVRQIAEQKQSDLLSYDLRNATKEVVGTCTSLGVTIEGTDPRAFKEQIESGEYDDLFADPANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6R7</accession>
    <name>U1P6R7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threonine dehydrogenase related Zn-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01424</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89267">
        <property type="protein sequence ID" value="ERG89267"/>
        <property type="gene ID" value="J07HX5_01424"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="2">
        <location>
            <begin position="29"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="396" mass="42174" checksum="3F78846DD07386B6" modified="2013-11-13" version="1">MAMSINGVVYEGERNVSVKPVDEPEIENPNDVVIDVTTTCICGSDLHMYEGRTSADPGIVFGHETMGIVSETGDGVSSLAVGDRIVAPFNVACGFCENCEDGLTGFCQNVNQTGDVPAGGAYGYVGMGPYQGGQAEKLRVPYADFNALQLPDEGHEDSFSLLADIFPTGWHGTELADLQPGDSVAVFGAGPVGLMAAYSAKIKGAGEIYVIDRVPSRLELAAKHCDANPINFDEGDPVEQIIAEHGGEVDKGVDAVGYQALDPEETDKGDDYSYNPAKENPAIVINSLIQAVRPTGKLGIPGLYVPEDPGAPDDAAAEGRLGIDFGKLFEKGQSLGTGQANVKAYNREIRDLIIEGRADPSWVVSHRVDLEEAPEMYDRFDNREGDTAFTKVLLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Z1</accession>
    <name>U1P6Z1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01495</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89337">
        <property type="protein sequence ID" value="ERG89337"/>
        <property type="gene ID" value="J07HX5_01495"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1727176_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012962">
        <property type="entry name" value="Pept_M54_archaemetzincn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012091">
        <property type="entry name" value="Pept_M54_archaemetzncn_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15910">
        <property type="entry name" value="PTHR15910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07998">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005785">
        <property type="entry name" value="Zn-prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="16328" checksum="7EE49B03D1954B9E" modified="2013-11-13" version="1">MAAEVHTQVPYETLDIEAQTPPYDGETLLSPGTQRETNRPSVIITRLSVTHDDRAFVFGIADTDNSVCLVSTYQLFQSADDPDDYTDPTTASERVRKEVAHEVGHVFGLSHCDTAGCVMNFSMQLADIDAKTESLCAGCVSTLTAAEDPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7C8</accession>
    <name>U1P7C8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01621</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89462">
        <property type="protein sequence ID" value="ERG89462"/>
        <property type="gene ID" value="J07HX5_01621"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041771_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="330" mass="34716" checksum="083A8B839F5751E9" modified="2013-11-13" version="1" fragment="single">MNRQQGFLLLLLVVTAVASFFVLLPFLQWVLGALLLGYILRPVHARLEPQIGEQVAAFTVIAGAAVAIVLPLSFIGLVVSRDAQALASGNTELNIEAVQTELNNVTGVGFDLVGATSDLGALIIDFFGANAPAIVGYLVDTLLGLTLVLFLVYYVLVDGPEFVQWAVTMAPLDDAVARELVVRTDRMAWSVVAGHIFVALVQGLIGGLGLAIAGIPSVIFWTTVMTVTALLPVIGAFLIWGPAVGYLYLGASDPTAAAFLLVWGLIPVSLVDNYLRSIVIDQSANVNPGVILVGVVGGVYTFGPVGLFIGPLVIGLLAAVVRAIDTHYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7D1</accession>
    <name>U1P7D1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00187</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88046">
        <property type="protein sequence ID" value="ERG88046"/>
        <property type="gene ID" value="J07HX5_00187"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="43"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="215" mass="22672" checksum="6DFC679CBDE5E155" modified="2013-11-13" version="1">MNTASRRGFLAAGAAVMASAAGCLGVLSNSYNPTAKPDEIGMTRPTQGPDDAPVRVIAFENFGCGHCATFNESVLPVLLDKHVRPGTVQYLHADFMLSRSAENYPAGNAARAVYETAGNDAFWPFGRAMYQYRSGSLSLQTIEDIAEAAGGVGTAARTAAKNGGYAEALSADTELGAEWGVDRTPTVFVEEEYVNPFDNGDPDPDALVEAVEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7E7</accession>
    <name>U1P7E7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA splicing endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01643</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89482">
        <property type="protein sequence ID" value="ERG89482"/>
        <property type="gene ID" value="J07HX5_01643"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114393_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006678">
        <property type="entry name" value="tRNA_intron_Endonuc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036740">
        <property type="entry name" value="tRNA_intron_Endonuc_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02778">
        <property type="entry name" value="tRNA_int_endo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="SSF53032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55267">
        <property type="entry name" value="SSF55267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_int_endo_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="15872" checksum="236ADAC270974B39" modified="2013-11-13" version="1" fragment="single">MELSFDGEAVHGGNAARERFYDSRGYGTPTDGGLLLAPVEAAHLLFRGDLEAVVDARPGGDGRLGFRAFLTAAVPEVAFLVYKDLRDRGFYLSSASEGANRFVVHPRGDGPWDDTVAYQVLAVSERAPVAAATLRGLAHEPATGVLAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7L5</accession>
    <name>U1P7L5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mn-dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00274</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88131">
        <property type="protein sequence ID" value="ERG88131"/>
        <property type="gene ID" value="J07HX5_00274"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="16729" checksum="3B6939F092E33932" modified="2013-11-13" version="1">MNAARQYLRAIYLIQELEDGRASTGGVAEMLDVSPASANEMIGKLERDGFCDHEKYRGVDLTDDGIVRARESLQHYCTLERFLANVLAVESYREEAAQLEPVIDEVVADRLDTLVNRREVCPDCFDPDTGVCAVLDVDSASDVGVDVDADAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7P8</accession>
    <name>U1P7P8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01748</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89582">
        <property type="protein sequence ID" value="ERG89582"/>
        <property type="gene ID" value="J07HX5_01748"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="2">
        <location>
            <begin position="42"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="203" mass="22736" checksum="9EC1A0201F452ABD" modified="2013-11-13" version="1">MSDNTNPDTNANADTDTDLTPETTDTRVRAGWQGRFYEDFTVGDVYKHPYGRTVTETDNVWFTNLTQNLNPMHFTEPYAADTEFGERLVNGLYVIALAVGMSVIDISTNATANLGYDNVRHHAPVFHGDSIFAESEVRSKRESESREHVGLVTTELRAFNQDDELVLSLERTPMVLKREYADPSPAQPPGWPAEIGTQPQADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P802</accession>
    <name>U1P802_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00419</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the archaeal NMN adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88276">
        <property type="protein sequence ID" value="ERG88276"/>
        <property type="gene ID" value="J07HX5_00419"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108783_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00243">
        <property type="entry name" value="NMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006418">
        <property type="entry name" value="NMN_Atrans_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01527">
        <property type="entry name" value="arch_NMN_Atrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="6">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="174" mass="19399" checksum="C125C63DC2CE53A0" modified="2013-11-13" version="1">MTTRRGFFIGRFQPVHNGHVQLIEQIASEVDELVIGIGSAGNSHTVDDPFTAGERTMMVRTSLESLPVRVYAIPIEDLNRNAVWVSHVQSMTPRFDIAYSNNPLVIRLFTEAGVAVQSTAMYNRDHLRGRKIRQLIIDGEDWGQYVPAAVENVIDEVNGIERLRSVDGGDGVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P863</accession>
    <name>U1P863_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00470</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88326">
        <property type="protein sequence ID" value="ERG88326"/>
        <property type="gene ID" value="J07HX5_00470"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3419901_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="26" mass="3055" checksum="57E9BC233B667655" modified="2013-11-13" version="1" fragment="single">MTGRVYKLHSTLELPLEDLHEYLEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8G3</accession>
    <name>U1P8G3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00551</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <location>
            <begin position="43"/>
            <end position="279"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="11"/>
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        </location>
    </feature>
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        <location>
            <begin position="79"/>
            <end position="86"/>
        </location>
        <ligand>
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        </ligand>
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    </evidence>
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        </source>
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        </source>
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            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="369" mass="39155" checksum="5648BF39A7E20E12" modified="2013-11-13" version="1">MVDSARTDRRGAETATSMSGTDSDTESGFDSGSESRSGAESALAIDGLSKRFESGDATVVAVDDVSLTVDRGAVVGLLGPNGAGKTSLIKCALGIVVPDAGTIRVLGTNVTDGRRAAYADVDAMLEGARNDYWRLTVRENLRYFATIHGVDPDSVAGRHTQLLERFDLAEKADTPVRALSRGMKQKVSLASALAGGAALVFLDEPTLGLDVESSRTLRHELRRLAREEGLTVVLSSHDMGVIEEICDRVVMMADGRIVADDTVSALLAEAGRNTVRVTSSDIDETVVAALRRQFTVQAAEIKATTHRSHVEVGAAGDALYELMDTLREAGVTVEEIETVQPSLEEVFVDLTGMGSTSSGDTGQRQERSP</sequence>
</entry>
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    <accession>U1P8Q1</accession>
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            <fullName evidence="1">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">J07HX5_02085</name>
    </gene>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="entry name" value="DUF2240"/>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="16103" checksum="5506DE279E7D34AF" modified="2013-11-13" version="1">MSLRRAVAAPFRDRGVDRMHTSEFIVALSLDRNWFSPDQAERVVSLAVSDGLLERTADELVVSFDAADTTIPDGFVPDEEILTQRSTFERILDAVVDAGTDKRTAVAEINQLQNKLDVTIEAAAALYARRQGVDVSDLATRARARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8W8</accession>
    <name>U1P8W8_9EURY</name>
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        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_02160</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="HTH arsR-type" evidence="3">
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            <begin position="31"/>
            <end position="111"/>
        </location>
    </feature>
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            <begin position="150"/>
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        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="314" mass="33538" checksum="B2B4AC7407983E96" modified="2013-11-13" version="1">MGSLFPLRGSVSADEDRDPRLVDLDEDTADEVFDALSSRTTRTIFLELHDQPQATSDLADVTDTSVQNVQYHLEKLTEAELIEVVDTWYSERGSEMNVYAPTDESLVLYAGRDKQSSLRTILRRLVGAVGTLVPVSIGVGWFAGRDSGGTRSGFESSFSGDPASVNQSGDERMTEAEAVESSGNDAGAADTSSDVSDTGNSDLDTQTEDLKQETSVSDVADLSEISDLQALSTTVDGKIDISSDQFLIEAGNQSVNTTARLQSSPNETALIVNPADLASLTTQSSGTDPVIVGLAFFLGGLFIMTVATVWSVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8X3</accession>
    <name>U1P8X3_9EURY</name>
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        <recommendedName>
            <fullName evidence="2">Glycine--tRNA ligase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00732</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88586">
        <property type="protein sequence ID" value="ERG88586"/>
        <property type="gene ID" value="J07HX5_00732"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_1_0_2"/>
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    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
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        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="5"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="577" mass="63495" checksum="3D1A9EB25AD5D0F1" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8X8</accession>
    <name>U1P8X8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00737</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88591">
        <property type="protein sequence ID" value="ERG88591"/>
        <property type="gene ID" value="J07HX5_00737"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504832_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9355" checksum="E72A5E7F25F04C1B" modified="2013-11-13" version="1">MNRELEKNGGRGEGWGLSRIFGVCLQDKTHQLIMSSGIGHPRSVSPTETDRSGRCPDGSSLWAPAKSRESKRQNTTRSPRIAVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Z9</accession>
    <name>U1P8Z9_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00757</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88611">
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        <property type="gene ID" value="J07HX5_00757"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053639_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="29998" checksum="4416CDDB504B6177" modified="2013-11-13" version="1">MYRLPFGISRLDEMVAGGAPAGSVVLLSGEAGAGAREFMQTVAVMNGLAVTDHELFKRHYGCLATDTRLPETISYLTVTADPAAVRSEIGLWMNTTLAEAGLERVRLCSVASAVFRDSRVPQHWYDDSEATRNDDPSGEPTELLAALCRRLTNYAPNGLVIIDSLSDLVAAAAGIDWSEISVLLHGLRTAAHRWGSLLLVRVSPDTLVPTEHGRLVDACSATITFEWTTNGSTRARTFVIQAFRGVLSGLPAERLVRFETDLSETGFHISDVRKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P933</accession>
    <name>U1P933_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00792</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88646">
        <property type="protein sequence ID" value="ERG88646"/>
        <property type="gene ID" value="J07HX5_00792"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447549_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9879" checksum="E5EF6C32F1248C80" modified="2013-11-13" version="1">MPANDSLRAEHATIQELTNLLTDVAEELSLSFDGWQETYVRGPSLYFVIVADVWIDDXXXXXXXGSRASSTLLRVPAEQHRSAPAQGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>U1P954</accession>
    <name>U1P954_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6 7">Histidinol dehydrogenase</fullName>
            <shortName evidence="6 7">HDH</shortName>
            <ecNumber evidence="6 7">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisD</name>
        <name evidence="14" type="ORF">J07HX5_00812</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7 12">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="6 7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88666">
        <property type="protein sequence ID" value="ERG88666"/>
        <property type="gene ID" value="J07HX5_00812"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_3_3_2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 11" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 8">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 8">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10 11">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 10 11">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10 11">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10 11">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG88666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="422" mass="43708" checksum="555F53D77625DD5E" modified="2013-11-13" version="1">MNPQRTDELSPAEQQGLFERDSGIESARAGAAEIVERVRTDGDAALRALADELDGVQTDTVEITDQAARAVETIDPAVRSAIETAAGNIRAFHERQRPEDWRETFDGRELGRRFRALDSAGVYAPGGTAAYPSSALMGVIPATVAGVDHVAVATPPAETVSPATLAAAEIAGADAVYQVGGAQAIGALAYGTETVTPCDVVVGPGNRWVAAAKAVVRGDVEIDFLAGPSEVVVLADASADPELVAAELLAQAEHDTRAAVAAVTDDPELAAAVSRAVDRQLGERERETIIREALASDASGLFVAPSLAAAAAFANRYAPEHLGIIAENDEALLDQIDSAGSAFLGPHSPVAAGDYASGPNHVLPTGGGPRRVGGLSVETFLRSMTVQRLDREALGELADSVTTLAETEGLEAHAASVRQRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAE4</accession>
    <name>U1PAE4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S1 RNA binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01223</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89071">
        <property type="protein sequence ID" value="ERG89071"/>
        <property type="gene ID" value="J07HX5_01223"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820155_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="36616" checksum="EEA6B4A84644776B" modified="2013-11-13" version="1" fragment="single">TVYNLAPECTAADVEEGEYYLATVNGAVDYGVFVDVSEAVSGLVHSSELSGEYAVDDELVVELDEIRENGDLSFTEVDHTAGEVEPRHPGSLVDGTDIAARAGEQVRLEGQVVQIKQTSGPTLFQVSTGAAVVPCAAFEAPGARAFPEVTLDSTVRILGTIEARTGHHQIEADTIRALTGADRAAVAERVSETRAAVATPDPIDPLIEWPAFEPLVEELSEIARRLRAAVLSGRPIRLRHHADGDGLCAGVPLQYALERFIGETWVDPEASRHLLKRLPSKAPFYELEDATRDLNFALESQRRHGQKLPLFLMLDNGSTEEDTPALPNAAGLRHSDPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAM5</accession>
    <name>U1PAM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01304</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89151">
        <property type="protein sequence ID" value="ERG89151"/>
        <property type="gene ID" value="J07HX5_01304"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="304" mass="31651" checksum="FAD437463C3A1B49" modified="2013-11-13" version="1">MHVVAVGGTGFIGRRLCAALLAAGHDVTALSRTPAPDILSGAVETATGDVTDCASITAALTDADADAVVNLVALSPLFEPPGGNKRHDIVHRGGTEHCLRAAAAAGVDRFVQLSALGADPTGPTHYLRAKGRAERAVQDSSLAWTILRPSVVFGAAGEFLSIVRRLTPPAIAPLPGGGQTQFQPLWVEDAAELIAAALAREHAGCIYEIGGPEVLSLAEIVQVVRGIDGRTPAVIPVPMAVAGLGLTLAGLLPGLPLGRDQYRALQLDATTTDTDVRTLGVTPEELTTVTAYLRRDRHTVVRQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAS6</accession>
    <name>U1PAS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01355</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89201">
        <property type="protein sequence ID" value="ERG89201"/>
        <property type="gene ID" value="J07HX5_01355"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3408334_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="29" mass="3060" checksum="BEC7F38CCAF4285D" modified="2013-11-13" version="1">MGYTVLAWIGSLVGAFVVGYLLLALVSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB05</accession>
    <name>U1PB05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative GTPases (G3E family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01428</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89271">
        <property type="protein sequence ID" value="ERG89271"/>
        <property type="gene ID" value="J07HX5_01428"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="3">
        <location>
            <begin position="256"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="360" mass="39423" checksum="5E2160D4FFE93C0C" modified="2013-11-13" version="1">MTQSETAPVPVTIVSGYLGAGKTTLVNHVLSNQAGYDVAVIVNDMGEVNVDAELIAREDETEGIVDLSNGCICCQLQDDLLTEARRLIDQRTFDYLLVEPSGISEPVPVARTFLEADGIGDQFELDTMVTVLDSYGFHKEFDGSDDPPGTDAPERSLSEVFIDGIEFCDVLLLNKTDMVPEDALQEIEAVAANLQPRAEQIRTSYSEVAPDRVLGTGRFDFAAAKASQGWKRQLRDDDHNHDHDHDQQSQADRHGVRSFVYRADDPLDPAQLGAWLSEWEESVVRAKGVCFVGGRDEVIGVSRAGPSIQAGPIGEWGPDDTRATRLVFIGREMPEPDIRAGLDECRLGPDQRPGSDPFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBC3</accession>
    <name>U1PBC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01514</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89356">
        <property type="protein sequence ID" value="ERG89356"/>
        <property type="gene ID" value="J07HX5_01514"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629559_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8014" checksum="7398D5F45EA53D3F" modified="2013-11-13" version="1">MIYRAILILAATAVIASCLGGYAVLTNKTSIDPGDGRANEYLPSAQPSAGEVELPQRDTAVAGSGDPEHSISTLYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBP0</accession>
    <name>U1PBP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01652</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89491">
        <property type="protein sequence ID" value="ERG89491"/>
        <property type="gene ID" value="J07HX5_01652"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3130709_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5365" checksum="B57E5780E2B318C9" modified="2013-11-13" version="1">MPRVVGKLTDLSVLWRSETNQLSELVSTQALTSTSGLIRRQTAMSSDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBX7</accession>
    <name>U1PBX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KH type 1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01752</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89586.1"/>
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        </location>
    </feature>
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            <begin position="100"/>
            <end position="170"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89586.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="22003" checksum="03016447E3A8B5E5" modified="2013-11-13" version="1">MARIAPTHFSGVPAYKLSMQHVTVPDDRVGVLIGRGGETMREIEDRAEVRLDIDSESGTVRVERVGDPVTGLNGPDIVKAIGRGFAPEEALSLLNDEMMMFELIDINAAARNESDLRRKKGRLIGEDGRTRELMEELTGTSVVIYGSTLGVIGGPQQVEAVREATEMLLEGAPHGAVYSFLERKRNELKHKGMDYHPYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFK1</accession>
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        <submittedName>
            <fullName evidence="3">Na+-driven multidrug efflux pump</fullName>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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            <begin position="12"/>
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            <end position="149"/>
        </location>
    </feature>
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            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
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            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="23657" checksum="B3EC29DBAED094E5" modified="2013-11-13" version="1">MPCDIVTLFSTSVVAGFGVGVRVFSMIFMPAIAIDRGVEAMTGQNIGAGREDRVVATNRFAAKVSFVILSVLGVLTFVFAPEIVRVFDSSPAVVAEGATFLRWIAPTFGFVGVLRAYSGGFRGAGKTVTAATIAVLLFGFIRLPIAYVASQGLVPIDLWFFSDPSPVGIWFAFAISGIIAAVAAASWFEYGGWRGGDLTEQSDASAGTDLTASEDHADSPAPTGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="12534" checksum="943E408F38F70F73" modified="2013-11-13" version="1">MDSTKYELSELRADDVRQYKPTKRLIVWEWYCKRCEERIGYPYMSATHATVCEDPGSCPRVDRQTGTPCGDTVCAWCHTPAVRQTIEWTDPEAVESVAAEIGLDGRVSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGF0</accession>
    <name>U1MGF0_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_00432</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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    </dbReference>
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            <begin position="45"/>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="273"/>
        </location>
    </feature>
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        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="274" mass="29352" checksum="C6A9714110CD5FB6" modified="2013-11-13" version="1">MLHGDAFGLFVGAAALGAVHGIEPGHGWPVAASYALDQTNNWAYGLAASLIIGVGHLISSFAMVGVFFYAKGYFSLTQVDEPVTILRGIQIGGPVSLLAGSLLLWLGVREYFHGYSHGSHTSDAHSNPHSHDHQGPDEHSAHPHEQDRSHNQSGLIARLKKLIPSVVGHSHSHDDHEATTDRGLLGIAWFAFVLGFAHEEEFEIIAICAGSNYCLELMSVYALAVIAGIVGLTMLLIAGYHHSKETVEQYTPYLPVFSAAVLIVMGLGFITGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGI6</accession>
    <name>U1MGI6_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Inosine-uridine nucleoside N-ribohydrolase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_00473</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="9"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="15979" checksum="0642AF8F3AB63D66" modified="2013-11-13" version="1" fragment="single">MPTDPPRRVIVDTDTAGDDAQALLMAATSDRIELEGVTICAGNVEFEYEVENAKYALELAGATEAVTVYEGAREPLVKDYTHAEYVHGEGGLGGDLFPDTGIDSGSQHAVEYIVETVRDNPGEITLACIAPLTNVAMALRQEPALGELLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGY5</accession>
    <name>U1MGY5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00660</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88514">
        <property type="protein sequence ID" value="ERG88514"/>
        <property type="gene ID" value="J07HX5_00660"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="94"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="203" mass="22985" checksum="A09B8510C5C58B19" modified="2013-11-13" version="1">MAQRSQPQLPELPYEYDALEPHISEQVVNWHHDTHHQSYVNNLAAAEETLAENREAGDYDGTAAAIRDVTHNTGGHYLHTLFWENMHPDGGGEPSGELRDRIETDFGSYEGWKGEFETAASDASGWALLVYDPVTKQLRNATVDNHDEGAIWGAHPILSLDVWEHSYYYDYGPDRGGLIDGFFEVVNWDYVADQYDTVVSRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH30</accession>
    <name>U1MH30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type oligopeptide transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00730</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88584">
        <property type="protein sequence ID" value="ERG88584"/>
        <property type="gene ID" value="J07HX5_00730"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091897_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="30"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="27548" checksum="90C5A9537DFD1713" modified="2013-11-13" version="1" fragment="single">YFPTSVLDIEREEEEVETDDGGTATRVVPGSVGVEATGDYTFELTLNEAFGFTIDVLAYSAFSVVPEGIVGDIEGYEGDVSFNEFSTNPIGCGPYSFEQWDSGNGGTFRASAFEDYHGGDVPVANIEDAILTEDTARYNRFVNGNADAAGIPTSQYEPDKVNLTGGDSAQRLGEYGPIGDGTTVNMSRTPTLNTFYVGFNVEKVPKAVREAMAYVINREAFVEQVFKGRGQAAFHLVPPPLFPGGGEGYRNHWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHD4</accession>
    <name>U1MHD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00870</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88724">
        <property type="protein sequence ID" value="ERG88724"/>
        <property type="gene ID" value="J07HX5_00870"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1762537_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="15358" checksum="B610A85CD3FE213E" modified="2013-11-13" version="1" fragment="single">YTSLRQVHLPSLDRANVVQFDKQRGTIDLDTGFDRVSAHLVYALHSAPSAETEMLADQVDPALTSPPTPDSPAAEHNVDTADQTAGVTRLRLLVGGVAVLAVLAPGARMFDNALAALEVQSGAVLVVSVASLCLATAAALFVSLLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHQ5</accession>
    <name>U1MHQ5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit beta</fullName>
            <ecNumber evidence="6">3.4.25.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">20S proteasome beta subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Proteasome core protein PsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psmB</name>
        <name evidence="9" type="ORF">J07HX5_00995</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88849">
        <property type="protein sequence ID" value="ERG88849"/>
        <property type="gene ID" value="J07HX5_00995"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_7_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02113_A">
        <property type="entry name" value="Proteasome_B_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019983">
        <property type="entry name" value="Pept_T1A_Psome_bsu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03634">
        <property type="entry name" value="arc_protsome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="4 6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="5 6" id="KW-0865">Zymogen</keyword>
    <feature type="propeptide" id="PRO_5005088895" description="Removed in mature form; by autocatalysis" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023458165" description="Proteasome subunit beta" evidence="6">
        <location>
            <begin position="46"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6 7">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="240" mass="25522" checksum="141ABCA9568ADA1A" modified="2013-11-13" version="1">MEKRVPGSLSREHTNRFETDPREPELGTLPSNESDNDSDMVNKTGTTTIGISTTDGAVIATDMRASLGGRIVSSKSVQKVEQIHPTAALTLVGNVGGAQSFIRTLRAEVKLYEARRGEEMSMQALSTLAGNFARGGPFFRINPILGGVDEDGSHIYSVDPAGGVIEDDYTVTGSGTTIAYGTLEGRYEEEMSIEETREAAAAGVKAATERDTGSGNGIYLAEITADGVEITEHDLNEFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHZ2</accession>
    <name>U1MHZ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01102</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88954">
        <property type="protein sequence ID" value="ERG88954"/>
        <property type="gene ID" value="J07HX5_01102"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="44"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="76"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="288" mass="31672" checksum="25AD22C221FBB49A" modified="2013-11-13" version="1">MSESEPEEQIESTNEQNESASLIDMHVTTATGTDASQARGQSVVEARDLDVHYGDEQALKSVQLDIYEQEVTAIIGPSGCGKSTFLRCINRMNDLVESASIDGKLRFRGTDMYGDKIDPVALRRHIGMVFQHPNPFPKSIYDNVAYGLRVQGRTVTDEIVADALKRAALWDEVNDQLHTSALNLSGGQQQRLCIARAIAVDPDVLLMDEPASALDPIATSKIEDLIKELASEYTVIIVTHNMQQAARISDRTAVFLTGGELVEVDDTATIFNDPNDQRVEDYITGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI30</accession>
    <name>U1MI30_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01159</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89009">
        <property type="protein sequence ID" value="ERG89009"/>
        <property type="gene ID" value="J07HX5_01159"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3369622_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="34" mass="3456" checksum="062F2FA95A199768" modified="2013-11-13" version="1" fragment="single">AGQLGVAAGLAVIVVVIAVVGYLSRDRLATLFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIE2</accession>
    <name>U1MIE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AAA family ATPase, CDC48 subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01312</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. CDC48 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89159">
        <property type="protein sequence ID" value="ERG89159"/>
        <property type="gene ID" value="J07HX5_01312"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_12_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="SSF54585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_N" evidence="5">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48_2" evidence="4">
        <location>
            <begin position="102"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="223"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="496"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="716"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="753" mass="82211" checksum="7E56983B4C81CAB6" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIG0</accession>
    <name>U1MIG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type 2 lantibiotic biosynthesis protein LanM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01337</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89184">
        <property type="protein sequence ID" value="ERG89184"/>
        <property type="gene ID" value="J07HX5_01337"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_468233_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="582" mass="62098" checksum="2B25EC7FF978A33C" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIK2</accession>
    <name>U1MIK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01394</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89239">
        <property type="protein sequence ID" value="ERG89239"/>
        <property type="gene ID" value="J07HX5_01394"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033401_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="208" mass="22158" checksum="5E56BEE9561B3743" modified="2013-11-13" version="1">MVNLGSHDQLSEGDIGENANLQGTDLFDADLRGAYLTHANLDDADLINADLRGVDLRNASLRGTDLYGADLDGANLSKADLSTADLRNVDLFMADLSDANIEAADLGGAGLFDATLENANLDHADLRSADLPDANLRNVSLTETDLRNANLERVDLSNAKLHGTKVAGANVSTTRINNTTTITRGEEQRVISKQMLADLGAIIRSRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIQ2</accession>
    <name>U1MIQ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01457</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89299">
        <property type="protein sequence ID" value="ERG89299"/>
        <property type="gene ID" value="J07HX5_01457"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_392147_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="703" mass="75397" checksum="E00D3EF8D91B517B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIT2</accession>
    <name>U1MIT2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01492</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89334">
        <property type="protein sequence ID" value="ERG89334"/>
        <property type="gene ID" value="J07HX5_01492"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="24071" checksum="6D9878E51C2C925B" modified="2013-11-13" version="1">MTGTPPDPVAAETFDMALTLHADHGFNASTFAAITVASTFADIYSAVVAGIGGLSGPLHGGANQDVIELLTEIDERDQTASEWAHDRVEAGERIPGWGHRVYEVTDPRARILRSKLEDLSDADGDRRWVESTRAIRSALTDELSFLEKGIAPNVDFYSGAVYEKLGIPLDMYTPIFAMARTAGWVGHILEYQTENRLIRPRARYVGHDDRTFRPVGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ19</accession>
    <name>U1MJ19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01588</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89429">
        <property type="protein sequence ID" value="ERG89429"/>
        <property type="gene ID" value="J07HX5_01588"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3110641_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="5910" checksum="E38503BA48A55E1F" modified="2013-11-13" version="1" fragment="single">MSKRSVQRLIKKIATVAEVRPYTDDFQRVAPDTLTPHSLRHSVAYRIISEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ45</accession>
    <name>U1MJ45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01628</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89469">
        <property type="protein sequence ID" value="ERG89469"/>
        <property type="gene ID" value="J07HX5_01628"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_904910_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="23"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="315" mass="33620" checksum="B8810534C9F7E172" modified="2013-11-13" version="1">MDSTKPGQLMIQTSALTSSTPIRLAIIADPHVGTRATGSSKLFEHSLDHFKTAVADITARDVDAVLSPGDLTKDGEPWNVAAVEAAIADLDVPFLAVPGNHDVAKTRDKHDVMSVGSFADQFGPGSYPFHEQIGEVDVLGLNSAGSGDRLFETHDGCVSTEQLDWLRSKLAVSESPLVLVHHNLESVTAQIKRHRDVAADEMAIPPTMRERGRFIETLARGSSPVVLTGHLHLPLTGVDQGVREITAPTTCSFPQSYLLLTVTASGTEVRVVPVTDMDGLELAHDRRARDSPTARGLTSIGAARMASLPLAVDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ51</accession>
    <name>U1MJ51_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative RNA-binding protein containing KH domain, possibly ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01640</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89479">
        <property type="protein sequence ID" value="ERG89479"/>
        <property type="gene ID" value="J07HX5_01640"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095994_5_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8707" checksum="D1C25484274BFBA0" modified="2013-11-13" version="1">MSSPNQASQSLDITVWVGKRGPEAVTDELDDQLSSRDSVKVKFLRAARAGPDTDTETLATELADHVGGTVIETRGHTAIIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ98</accession>
    <name>U1MJ98_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Erythromycin esterase related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01705</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89539">
        <property type="protein sequence ID" value="ERG89539"/>
        <property type="gene ID" value="J07HX5_01705"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026490_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14728">
        <property type="entry name" value="Ere-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014622">
        <property type="entry name" value="UCP036794_erythomycin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036794">
        <property type="entry name" value="UCP_erythr_ester"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="450" mass="50609" checksum="B28BBC40818F37F1" modified="2013-11-13" version="1">MTDKTPTNESTTTAHAVTDELAERLQRSSVELSTTDPSDGHADLAPVGDVVINARIIGLGEATHGTREFFQLKHRIVRYLVEEQGLRLFMMEVNLPETMALNNYVVHGKGDALEALAGTHLWVWRTEAVLALVEWLREFNAGRPLDDRVRFYGIDAQYTTGAVEYLDEFLARADPDLREELQADLAATDDEGNNNDQYMSDHDPEATDRLLNRLGTAFEERREAFVIMTSERETALARRCLRIVEQARQRRVARETDGIQASMVVRDEAVAENLSWALDYEAADRAVLWAHDSHICRTVHFGARTDPAPSLGSYIADRYGDDYFALGFDFLGGSFRAIGIGLPPESERSAWSLNEPPADSITRMFADTRSDLMFLDFDTAKKDDRLDEWLAEPRAKRKLGAVYYDPDGPSEDEKDGQAAHNAVRILPEAFDGLLFVRETMPSRVLDSPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJH6</accession>
    <name>U1MJH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xaa-pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01804</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89634">
        <property type="protein sequence ID" value="ERG89634"/>
        <property type="gene ID" value="J07HX5_01804"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="153"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="405" mass="44636" checksum="212D366A25BAFCBB" modified="2013-11-13" version="1">MESRLPEHAYEARIAAVREKLATTDADAAGWFSATSIGYLTGFHHIQTERPVCLVVTPETTGIVVPRLERERVTPNERIQAVRTYFDYPGGEPIVTIATLLEELGVNRLCADAEGPPGTMGYAGPSLTESLTVTSQSWVDRMRWAKSDAELDLIRESARWGDRAHQYLADGIEPGAHPVTVSQRASLQGSQAMLDTLGDQYVPRTRETGPVHAGFISGRQTRLPHGHTANRRLERGDVLVTGATANVDGYRSELERTMFLGAASDDHRDYFELMHEAQTIAIEALEPGGTLAAVDQAVWEYFDEQGITDLARHHVGHNIGIGSHEPPYIDRGWTKHCERRDSRDAADRTIEPGHVYTIEPGIYTDTAGYRHSDTVAVTDAGTERLTTFPRDLTANIIDIESNGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJM6</accession>
    <name>U1MJM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01866</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89694">
        <property type="protein sequence ID" value="ERG89694"/>
        <property type="gene ID" value="J07HX5_01866"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1849168_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="138" mass="15025" checksum="82AD4DA1D6719ABF" modified="2013-11-13" version="1" fragment="single">ARVDDPPQGPFDRAQQVPPEQPTTDRARQMAAEIDATIDGATRADRDGEGEAIADLRESLVETATVVYAATTDSTPATAKAAVEAGEWTDDKAAAAFLAGETMPLPGARLRLWLTPERERRRRIRRTVTAIEQLQDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJW3</accession>
    <name>U1MJW3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsZ</name>
        <name evidence="10" type="ORF">J07HX5_01966</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89794">
        <property type="protein sequence ID" value="ERG89794"/>
        <property type="gene ID" value="J07HX5_01966"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024865_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
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        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 6 10" id="KW-0132">Cell division</keyword>
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    <keyword evidence="3 5 6" id="KW-0342">GTP-binding</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="8">
        <location>
            <begin position="62"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="9">
        <location>
            <begin position="256"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
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        </location>
        <ligand>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
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            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="40876" checksum="4D9DF4922C00AC21" modified="2013-11-13" version="1">MDSIIDEAIEDNEGEDTVDAGSRSGSGESRDSQPERADSDGNNSGTMTDAELASVVEDLETKITVVGCGGAGGNTVTRMTNEGIHGAKLVATNTDAQHLADEVEADTKILIGKELTGGRGAGSIPQIGEEAAQENITDVRGAIDGSDMVFVTAGLGGGTGTGAAPVVAQAAQDAGALTISIVTIPFTAEGERRRANADAGLERLRSVSDTVIVVPNDRLLDYAPSMPLQDAFKICDRVLMRSVKGMTELITKPGLVNVDFADVRTIMENGGVAMIGLGESDSENKAKDSIQSALRSPLLDVEFDGANSALVNVVGGPGMAIEEAEGVVEEIYDRIDPDARIIWGASVSEEAEGHMETMIVVTGVESPQIYGRDNEQSQSQSQSTGSEIDYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJY4</accession>
    <name>U1MJY4_9EURY</name>
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        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">J07HX5_01991</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89819.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18840" checksum="9E4EE27D6603D785" modified="2013-11-13" version="1">MGRTDTDLDFDADVEIDLSTTACETQTLVLSESRLRALRTWAVDGTGVAAGARVYDDTGRIVLIKNSWTDGWFVPGGKVEHGEHLRAAAKREVREETGLTVTVGEPVVAIDQRYCTTETTNPRFRAAFVVYAAQATGTLSVSTPDGDEITAARWFETLPELHDSEYIRPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK17</accession>
    <name>U1MK17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_02021</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89849">
        <property type="protein sequence ID" value="ERG89849"/>
        <property type="gene ID" value="J07HX5_02021"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11791" checksum="F768AE5E3E93D22E" modified="2013-11-13" version="1">MQQPEPADGWPDRPLSEAEAADRLEDGVAVWVMDHEDGVRSATVPRDAPDDAVVDLVLETAAAFEMYSYSGGQWMDYGTQRKDDEDAPPMAGTLESYRLLAGESDALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK19</accession>
    <name>U1MK19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02026</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89854"/>
        <property type="gene ID" value="J07HX5_02026"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1472044_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="183" mass="19183" checksum="8CE2A3C4CCACFEBE" modified="2013-11-13" version="1">MTAAAAGAKILDAAEDLAELGSHAAQVRREITATDTLSRPLSELLATVRNTLADTPATVDGPAADTPVLVSAQTDKALSWLLARIVEYTDDPGVSVRVDLRANHVELNIGGPAPLLSAGDAALITTGTETALEHGQNMDVARAYLTLTSVGGEIIQTDDTSTRRSFRIEVPRLDGDRTLADQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK76</accession>
    <name>U1MK76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Archaeal Glu-tRNAGln amidotransferase subunit E (Contains GAD domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_02127</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89954">
        <property type="protein sequence ID" value="ERG89954"/>
        <property type="gene ID" value="J07HX5_02127"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1071519_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004414">
        <property type="entry name" value="GatE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF2">
        <property type="entry name" value="PTHR11659:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="6">
        <location>
            <begin position="114"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="259" mass="27251" checksum="104E5D8FFE0998F1" modified="2013-11-13" version="1" fragment="single">EAVGAGPADAVALVADDSETASLAIDAVAERAAAAIEGVPEETRGATDDATTQYLRPLPGAARMYPETDVPPVTPDPTTVDPPELLTEKVERYQTDHGLAPDLAEQIAYDERMQLFERAVDTGVDPTLAATTLMSTLTELRRDAVPVETLTDDQLIETFELVAAGELATEGVPDLLTALAAEPTLSAATAAEREGLGSAGEGDVRDAVQTVIERNSTQVTEEGMGAFSALMGECMGELRGKADGDIVSNVLREEIQRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV52</accession>
    <name>U1MV52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00101</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87960">
        <property type="protein sequence ID" value="ERG87960"/>
        <property type="gene ID" value="J07HX5_00101"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783889_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7765" checksum="0472C66415671CAA" modified="2013-11-13" version="1">MRPRQRLNCFVHADSFDRRYDNPNRRPDYISVPSGVSAIAIPVYSLKTAGYPDYFCRLQSSDGYCLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV59</accession>
    <name>U1MV59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00111</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87970">
        <property type="protein sequence ID" value="ERG87970"/>
        <property type="gene ID" value="J07HX5_00111"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353112_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10839" checksum="FCEAFCA6E88632CF" modified="2013-11-13" version="1">MSHIVHVLPEAPWQRFKEYGEYRLDSLADQGFVHCSKLGQVVVVADYNYTDSDELRLLVLAESNXXXXXXXRSTALTTILRGCQSGTARKTLLWSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVD7</accession>
    <name>U1MVD7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00212</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88070">
        <property type="protein sequence ID" value="ERG88070"/>
        <property type="gene ID" value="J07HX5_00212"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169408_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="10509" checksum="6172B27C0560744D" modified="2013-11-13" version="1">MPAQRTVCIRTPHSRPAALAAALRPDNTNDVRSRVEDGAVVTEIARDSTGSLAQTTDDYVRNLRVGAQLLDQDNGLSTDTNTDANADTDPNTNADRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVE1</accession>
    <name>U1MVE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative GTPase, putative translation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00217</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88075">
        <property type="protein sequence ID" value="ERG88075"/>
        <property type="gene ID" value="J07HX5_00217"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037276_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="MMR_HSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="MMR_HSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="2"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="41391" checksum="665EADDDAC313F32" modified="2013-11-13" version="1">MLSVALAGKPNAGKSTFYAAATTADPEMANYPFTTVEPNRGVGYARTECPCLERDRRCDSDDCDDGTRYVPIELIDVAGLVPGAHEGRGLGNQFLDELTDADAILHVVDAAGATNAEGDPVGVGEHDPVEDLQFIETEMDRWLASILERNWESLVRGARSPGFAIDEALTELLTGVGATPADVAGILRDLSYPAAPADWTDDDRRSLATAVRRQTKPIVIVANKLDAADTEDVRRLQAAADTVVPASAASERALRRGADAGAIAYSPGDATVQVNDVSDDQQAGIARVQELLAEWGGTGVQQAIDTAVYDVLDQITAYPVRNASDWTDADGRMLPDAELLSTGATPVDLAYAIHSEIGDGYLSAVNARSGRAIGEDHTLTEGAVVQIVSTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVI6</accession>
    <name>U1MVI6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ORF">J07HX5_00268</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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        <property type="gene ID" value="J07HX5_00268"/>
    </dbReference>
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        <property type="reaction ID" value="UER00404"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LS/RS"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
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    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="71"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
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        <location>
            <position position="119"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58830"/>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="15247" checksum="2367CE85D6BB7FE7" modified="2013-11-13" version="1">MARPRLGLVVAQFDKQGGVVAEMEDSAREAAREHGADIIETLAVPGSYDTPLAADRLARRDSVDAVAVVGAIVTGDTDHDQLIGHAAADGLRAVALDRDTPVTLGISGPGMSHDEALARVDYGANAVESAIQMLTTLEDADDTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVQ1</accession>
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        </submittedName>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="618" mass="66506" checksum="1A5BEE383AD55F7A" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVS9</accession>
    <name>U1MVS9_9EURY</name>
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        </submittedName>
    </protein>
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    </gene>
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    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="252" mass="27471" checksum="614DE43533EB8469" modified="2013-11-13" version="1">MQIVGYEPAPVGDDSARLAVAEDGAVEWVSLAPGTQLSYGLGERHCAGTIEEGRHHACDEPTTPYCEHHTSRWPCARCTGGCTLPLASCREEHAVYMAAFAPAIFKVGVTRSWRLQTRLQEQGADRAAHLRTVENGRKARRIEAGIAARDNLTDRVRTTRKYQGLDRGVDTAAWDQTLAEFNPVTTHAFEYGLELNRQPVTETVAAGTVRGTKGRVLVLARAGSMYATDLRALVGHEVGADHGRLQASFDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW0</accession>
    <name>U1MVW0_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG88113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW96</accession>
    <name>U1MW96_9EURY</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88258">
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        <property type="gene ID" value="J07HX5_00401"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3261779_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4439" checksum="A3616550A4E987B0" modified="2013-11-13" version="1" fragment="single">AGLPKATFEPVVGRHLAFVEQSRPVTDRLLGFLEAVTGETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWE0</accession>
    <name>U1MWE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00441</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88298">
        <property type="protein sequence ID" value="ERG88298"/>
        <property type="gene ID" value="J07HX5_00441"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629821_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="76" mass="8460" checksum="C24E35F696B21000" modified="2013-11-13" version="1">MHTCQSCRQTFDSELALALHRDQCQTRLYCEACGTRFEEQAATEDGWHYQCIAEDCAGAGIGDDLHRVADAHVATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWJ3</accession>
    <name>U1MWJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00645</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88500">
        <property type="protein sequence ID" value="ERG88500"/>
        <property type="gene ID" value="J07HX5_00645"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="186"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="7">
        <location>
            <begin position="302"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="412" mass="47236" checksum="EAC9344F8E75A3E9" modified="2013-11-13" version="1">MKRTLRFRAYLSDAVASEAWRQIDILRQIRNHAVRGYYHSDYNERPTEFEQNNKLTEWAERWPTFAEPSRHAAQQAISQIHSDLETLKERRNNGYNVGRLRLQGRGEYRSVSYNQPCRWNVDHNTGGERCVQFRLEKIGWFKIRAERTVPDADEISEAILKKQKTGEWYVSLVIDVDDVPEKPGLSEIEPQDCVGVDLGITNYIHTSENLTVDTLDLSDEYERLRREQRNLSRKQHGSNNWEKQRRKVAKATRKIKRKVKDFQHKLTTWLVTEYDLVAVEDLDVKPMLESSQNAKNKQDAAWSRFIDLLEYKADLHGTHVVTVDPAGTSKECASCGVATDKPLWVREHSCPACGHTQDRDLNAAKNILNRGLKQVGAGRSESTPMQTALPTSSPQREAIDAKRVVEVGSLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP8</accession>
    <name>U1MWP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FeS assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00721</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88575">
        <property type="protein sequence ID" value="ERG88575"/>
        <property type="gene ID" value="J07HX5_00721"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_904598_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="307" mass="33676" checksum="2D8679F69A37FD64" modified="2013-11-13" version="1" fragment="single">GDLLEAEFGQTVPPERNYLTALSTALFSAGTLVYVPEGVRAKDVTIRTTMNSQSLFNYTLVVVEESASVTVLERQATGASPGDKQYYSGIVEAVAGENAHVQYGTLQELDEDAYNFQTKVGRAGQYGQVNWIEGTIGSRLNKSSVETHLEGSGSESKIVGAFFGHEDQHFDVASRVWHEAEHTTADLITRGVLDDDARSVYEGVQDVGSEAWDTNSYQRENTLMLSDESEADASPKLIINNHDTEASHSATVGQVDAEDLLYMTSRGIHEDTATDMLVEGFFVPVMEEIEVEEFRDDLETSVTARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWV5</accession>
    <name>U1MWV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglutaminase-like enzyme, putative cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00603</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88458">
        <property type="protein sequence ID" value="ERG88458"/>
        <property type="gene ID" value="J07HX5_00603"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_689846_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="TgpA_N" evidence="3">
        <location>
            <begin position="9"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="319"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="400" mass="42317" checksum="E2B222B60E8141CA" modified="2013-11-13" version="1" fragment="single">ITLAVFGLGMLWYLAALSYVPSVLGVLASNVELLTGRTLLRVDAVGRWVVVATPTLAFATWFLVLRRRYIAGAGVGAGAVSYLVLTGDAGTMVTLLGVVSTVGVIGSGDLERHGGSGPGIERLALVLAVMVIAPVLVTVVPGGSASPVSLTGGTQPSIESAVVTQNNLEIVGSVDQSPRVRFEVTGDEPRRWRTAAFDRYTGDGWVRTGDRTAAELTAPAGETRTRTYEYALRSQFSAIPTAWQPTTVTNLSSPTLQTSTGGLQVDGQLPAGEQYTVTAAVPNASRTAVETAGQAYPAAIADTYTQLPDSTPDRVATRTSKITQQATNPYETAVVIEEWLETNRGYSLDVDRPTGDIADAFLFEMEVGYCTYYATTMVAMLRSQEVPARLAVGYTPGEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWY3</accession>
    <name>U1MWY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00633</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88488">
        <property type="protein sequence ID" value="ERG88488"/>
        <property type="gene ID" value="J07HX5_00633"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2475870_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="9346" checksum="070E7629DB2DE31F" modified="2013-11-13" version="1">MQSNGPPVIDAIPYFIGIVGIAACSCTDIVYRLTAGRIAVRFNSASCTGVMIILIISFVRCPVPWTDLGIINPAANNTMKLCHHGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWZ6</accession>
    <name>U1MWZ6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">GTP cyclohydrolase III</fullName>
            <ecNumber evidence="1 2">3.5.4.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gch3</name>
        <name evidence="3" type="ORF">J07HX5_00649</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:22468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57258"/>
            <dbReference type="EC" id="3.5.4.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the archaeal-type GTP cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.29" evidence="1 2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88503">
        <property type="protein sequence ID" value="ERG88503"/>
        <property type="gene ID" value="J07HX5_00649"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080076_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043740">
        <property type="term" value="F:GTP cyclohydrolase IIa activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00608">
        <property type="entry name" value="GTP_cyclohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007839">
        <property type="entry name" value="GTP_CycHdrlase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42202">
        <property type="entry name" value="PTHR42202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05165">
        <property type="entry name" value="GCH_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009265">
        <property type="entry name" value="GTP_cyclohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="27560" checksum="9B9FAA486D6526A0" modified="2013-11-13" version="1">MVRTQLTLIQIDNYGPWTVTPHPRPEVDLQTLQSRLYADLSQLVGRDGGYVFYTRFDNMIAVTNTLDMADHERIQSSVRNRYPVTISLTVGVDDRPEGALAGATKQLQAAGSAQDGTRTEILGGEVIDPTNAGVQIAHFDVNSATERYTDQLSAFEVYQQINRGYVTLAGHMHDAHGALTFFVGGDNVIAVTPDLNQPAFQDAIEHVQEIADIDLKVGVGEGATATDAGMAAKEALEHCRETGDNVKLGAEPAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX63</accession>
    <name>U1MX63_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00881</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88735">
        <property type="protein sequence ID" value="ERG88735"/>
        <property type="gene ID" value="J07HX5_00881"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1590813_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18436" checksum="E55B5EA029EDE7C6" modified="2013-11-13" version="1">MEVAFRGTAVAEVTDDGSIIVHQIHRPGQPRRVWDLGSNRHRNTENICVLGRDAAGFATHPVQQDLLQWPPVCVHGGVFTIAWDQPVLVVHRERTGDLCGLLPRHRRIGAHPTLSLETDRPLVEVPGESEVAVHLDEPVVAEIRHRRALSNLTVLVENFDAVGGISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXA5</accession>
    <name>U1MXA5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fructose-bisphosphatase</fullName>
            <ecNumber evidence="1">3.1.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00769</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.3.11" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88623">
        <property type="protein sequence ID" value="ERG88623"/>
        <property type="gene ID" value="J07HX5_00769"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2269274_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="10890" checksum="6AAFF857BA61201E" modified="2013-11-13" version="1" fragment="single">SGYDLTVSPPAVYQQTRGVRRVGSVALNLAFVAAGNADGAWEFNTSPWDVAAGLCILEEAGGVATDGENTPYTFELDTAGTRKPLLVSNSSLHERLIERLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXH2</accession>
    <name>U1MXH2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00991</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88845">
        <property type="protein sequence ID" value="ERG88845"/>
        <property type="gene ID" value="J07HX5_00991"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2377484_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10667" checksum="3551022CF891ADBF" modified="2013-11-13" version="1" fragment="single">LCEQHQSPANREIITPPTRCIWCGACLSSCAVAGCDDRYLGPTAVNAAYRFIMDDREGKSRATERVNRLSREDGVWRCQTQFSCTDVCAKRDPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXH3</accession>
    <name>U1MXH3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="2">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rlmE</name>
        <name evidence="4" type="ORF">J07HX5_00849</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="211"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
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    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="275" mass="29321" checksum="3D31C8716ACFEE4D" modified="2013-11-13" version="1">MSNKDRYYNQAKQEGYRARSAYKLKQLDGTAGLFSPGDTVIDLGAAPGGWLQVAGERVGAAGRVVGVDRQRIEDPEVSARVETIQGDVTDTETITAIRRGLGVNTTNDGDELRGDRPVDAVVSDLAPNMTGTYDLDHARSVHLARQVLAIAEDLLAAGGDMAVKVFQGGDLEEFRGEVDAAFEYVRTVEPDASRDASSEVYVVGKGRLTAPVRPGDRAEVDIIDEGSEGDGVAKVEGFTLFVPGGEAGETVFVEVTDLKPNFGFAERVDDGVKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXP4</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_00924</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="30"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="515" mass="57906" checksum="E16BCD2CEBCD1A73" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXT0</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01093</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
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        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="216" mass="21511" checksum="91F6A1C107A57C3D" modified="2013-11-13" version="1">MVDLVAVTLVAGGAVLLFFGAVLSVYGVGLLGAAVGGGIAYLLGPTSLPGVGIEGSAATAAAVPVGALVGVIGTYMLLSLVISAIGFVIGGYIGMVAVAPALGETGLVVYGIGVALGVGTGVLASFLSKTTMVVVTSFVGATLVSQTITADEFVTAKENLSPEPLLFDPVTPLVLGLFALGVLSQFGLFKLSYVTGLIARLPGARRLRDRGENQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYB1</accession>
    <name>U1MYB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
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        <lineage>
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    <reference evidence="1" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_01313"/>
    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG89160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8437" checksum="D50947C5571E2220" modified="2013-11-13" version="1">MSLKKIFSENGLDVRRRDRANGIELIADLGSGVDAGVDIIGDTVIVVTGDEQYEIPGVEDARATINHGVLTIEVEDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYM7</accession>
    <name>U1MYM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01286</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89133">
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        <property type="gene ID" value="J07HX5_01286"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="157" mass="16959" checksum="A624D0AF5A61B411" modified="2013-11-13" version="1">MTATRPASGATYRQTTQAGRWLVTGGELPDRLCHRAVRRVLVEADTDRHGGHFGCNRLGCRAGFVRGDGRPGDQQLPRCAPESRRKSLSGGGLEQGVGRLSTAPVSVTEGLSQRASVARREPARGRCRLSLLTMAPVVRSCRTRVQLFPVKTIPTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYW0</accession>
    <name>U1MYW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01508</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89350">
        <property type="protein sequence ID" value="ERG89350"/>
        <property type="gene ID" value="J07HX5_01508"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3003007_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
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</entry>
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</entry>
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</entry>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="283" mass="29543" checksum="FCECE61C46DC4E4C" modified="2013-11-13" version="1">MSLKCSVFGHDFGPTETDREREEKGDEVVTTIRETETCNRCDMTQVITENTEVTHIDTGPTPAPEPTDEPPTTAPSTDPAAESVTDGGDSAVDPSTSASPDTTTVTETEPDGPDTLSTLPTAGPDDSDPETGEITSADDDGVILDPTNDERPPGEWPKNAPTEEDGYHAAWPANPTGDMGSPAEYSKMPSTAGTADETAQASETDVDGPDETAVANAPADEPETVTQTDPRPGPIDGVMTVPRGEFRCRECGHTESVASSSLRAGDFCPTCATGTLDHVTDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0N7</accession>
    <name>U1N0N7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02040</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89868">
        <property type="protein sequence ID" value="ERG89868"/>
        <property type="gene ID" value="J07HX5_02040"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965472_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13681" checksum="436C191D1070C5B3" modified="2013-11-13" version="1">MLRARLSPSNPPSPRRLVGIELDPAAVTWYASSTLGWRGRGSNNEHSQHRVRDADXXXXXXXXIGAYGRFPVVEFMSYGCLRPALYRWIKPSGSGLVPEVVHILHGVGILSIPGTNSVQDGAVGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3E3</accession>
    <name>U1P3E3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00158</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88017">
        <property type="protein sequence ID" value="ERG88017"/>
        <property type="gene ID" value="J07HX5_00158"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_707144_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="390" mass="41555" checksum="4FE3FE7D401BEE91" modified="2013-11-13" version="1">MSPRDTHTNEDNTRQTSQGRRRFLLGMGALTAALAGCTSDNTDESDAPPANGSENSSTTDDSSTDADTDTDADGFDPASELAYGKWLTAEDEQVLFAYSNLAAIPEDTAQSGLSDPSVDDPLLLYPLVISGVVVGLSRFSLLYAGLAQATTPNASSDSTVNELTVINRTVVAEGTFATDQLDDRLTEPTDQTFGVAHEQTGTIGEYDQYEPVEVPDSIQNAPVVAVTDETVIVSQDTDRLERTIAAGNGTQSRLFETDETVAALLEQAGTGDRVVGQLGVPYEQLAGGENQSIEPNPQFEPRSSEDVVASISFEEGGDSLDSAVALAAPEFDADRQETIESSFGTAATDGSRSVTVDDDRITASGTYDVEQLAEATAHRQRRRNWCHQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3N2</accession>
    <name>U1P3N2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00255</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88112">
        <property type="protein sequence ID" value="ERG88112"/>
        <property type="gene ID" value="J07HX5_00255"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_793672_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="365" mass="40014" checksum="E20B5B16D2A1DFC9" modified="2013-11-13" version="1">MRVAFVSSETTWRRDSADARRIERVAGLLAARGHDVTVFCAQWWNDYTAERTVDGVRYCGLTVGTATAAFVSRLPVALARYRPAVVHARLTPPHTALAARAGATVARAPLVVEHSGKQSIDGQRGTAAVAAADRIVVPSELVQTAVRQQGANKATTRTIPESIDYQQIAATDPAAGVDIVYAHSLDETANLEALLLALAELRSREWTATIVGDGPRREEYERQVEALRIADRVAFAGWPDRDRRRALYRGAHVFVQTATRVQFPLELLRGLAAGTVGIVEYHSGSSAHELIEKYDRSYRVTDTETMADAITAAGGLEHRTVDQRWQTYSHERVLEQYLSLYDELTDSEPNAASRPPRSAGAEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1P426</accession>
    <name>U1P426_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="11">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">alaS</name>
        <name evidence="14" type="ORF">J07HX5_00405</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="11"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88262">
        <property type="protein sequence ID" value="ERG88262"/>
        <property type="gene ID" value="J07HX5_00405"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_A">
        <property type="entry name" value="Ala_tRNA_synth_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022429">
        <property type="entry name" value="Ala-tRNA_lgiase_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03683">
        <property type="entry name" value="A-tRNA_syn_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="13">
        <location>
            <begin position="60"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="617"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="621"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="720"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="724"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG88262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="925" mass="101879" checksum="E758009F5D606D9B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4J1</accession>
    <name>U1P4J1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonine ammonia-lyase</fullName>
            <ecNumber evidence="5">4.3.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00567</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88422">
        <property type="protein sequence ID" value="ERG88422"/>
        <property type="gene ID" value="J07HX5_00567"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_1_2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04886">
        <property type="entry name" value="ACT_ThrD-II-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044561">
        <property type="entry name" value="ACT_ThrD-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005789">
        <property type="entry name" value="Thr_deHydtase_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01127">
        <property type="entry name" value="ilvA_1Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="328"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="409" mass="43318" checksum="F2F275BB812EC9BD" modified="2013-11-13" version="1">MIELSDVVAAQERVIDTTRHTPLSYSHGVSDSTGADVHLKLENTQRTGSFKIRGATNRIATLPDETLANGVVTASAGNHAQGVALAASRFDVDATVVMPEDAPISKVTATRDYGARVVLHGTDYDEAADRAREIEQAENRYYLPAFDDPAVMAGQGTLGLEILDDVAGVDTVLVPVGGGGLIAGVATAIKGRWPEARVIGVQATGAAAGAESFDRGERVTWEHVDTVADGIATRGLGEQPFAVITERVDDIVTVSDADIALAITVALEREKTLVEGAGAASLAALLADAFEYKPDETIVAALCGGNIDLNMLSTVILRGMIETGRYLQIRTVLPDRPGALERLIATIAATEGNVYAIRHDRSSRDISMDATEVEIDIETRGQDHVLTLLESLRDAGYTIERLTPPTPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5H8</accession>
    <name>U1P5H8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00938</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88792">
        <property type="protein sequence ID" value="ERG88792"/>
        <property type="gene ID" value="J07HX5_00938"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1258400_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="27"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="219" mass="25107" checksum="410C94FBD923986E" modified="2013-11-13" version="1" fragment="single">LYEKYIPDAQALRQSPEIQQYMWTGNLGPYELSSTTPGEAGDAIFERNDDYYMRDHVEESNVQVMDDGFAEAPYFERLLRDREPEQATLNERWRAGDGDRYVPDTDIIEELQQRDDTTVAEELSPFISMMFFNQRANGHPMLKSAEGRIAINSIVDKQVIVEDVKRGLEGPPAATYQPRWSQFYDDSLVTARGIGVENADIRAARDRIRELDGFSVEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5V7</accession>
    <name>U1P5V7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">J07HX5_01053</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88907">
        <property type="protein sequence ID" value="ERG88907"/>
        <property type="gene ID" value="J07HX5_01053"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012348_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0515">Mutator protein</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="14">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ERG88907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="343" mass="36762" checksum="D45CFC0323DF7DA0" modified="2013-11-13" version="1">MATASYEARAYGVESAQPISEALELLPRKIEAASDPTRPVADAGFYRPVDMEHYESVAAEVKQACRDHAATVREVSIDEAYLDVTDRTSWDGAESFAQSLKTAIDTQAGVTASVGLAPTMSAAKVASDHNKPDGLVVVRPGVVAEFLGPLNVEAVHGVGPVTAGRLERMGIETGADLAEADPAQLADVFGERGRRIVQFARGEDDRAVEPRGRPQSLSRESAFRTATTDDDRQRARLRALAEDVAERAARENALYATVGIKVITEPYEVATRERSLGGPVADAALLTELALGLHEEFAGEPIRKLGVRVSSLSFTNSDQQTLAAYSAADGPTSRQQSLDRFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6P5</accession>
    <name>U1P6P5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01403</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89247">
        <property type="protein sequence ID" value="ERG89247"/>
        <property type="gene ID" value="J07HX5_01403"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1140588_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="27937" checksum="B2F6FF339D69DDFC" modified="2013-11-13" version="1">MTHPRQQRLARVRRALRDRGFELEDNEQPGADGVVATGGQLPESQRPPTTPLAVTTPLSTEPLEIVSALDNAATQERVPLLVAAPESATAIRELLAAPSLLAGRNRGRLFYGVADRILLQEGGYACVAADRTATLQWHERATQAETDTPGLVLTVDETPQLTLASVATLRCPGPAAADVPYRYVRAEAGQFRVLAGDTDTPVGRYESTVAMRADGYRPVPLPLVPEHHIRTNGRYARSVVLATVSENGVQYEQPMRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6V2</accession>
    <name>U1P6V2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01460</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89302">
        <property type="protein sequence ID" value="ERG89302"/>
        <property type="gene ID" value="J07HX5_01460"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="45"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="33110" checksum="E3404751CAF298FF" modified="2013-11-13" version="1">MAESLADTDLPAARAALLEWYADDHRAFPWRETTNPYPILVSEVMSQQTQLERVVEAWQAFLEAFPTVETLADADRSAVVTFWTTHKLGYNNRARYLHEAAGQIIDEHNGQVPRDPGTLEELPGVGPYTANAVASFAFNNGDAVVDTNVKRVLYRAFGVTDKKASLTAAANELMPADGSREWNNAVMELGGVACQKTPRCDEASCPWREHCTAYRTGDFTAPDVPEQPDFEGSRRQFRGRTVRALGEHGPLSLNELGPRVRVDYVPDGDHGREWLRGVLTDLADDGLVELNGDVARLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P702</accession>
    <name>U1P702_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01505</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89347">
        <property type="protein sequence ID" value="ERG89347"/>
        <property type="gene ID" value="J07HX5_01505"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010179_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007390">
        <property type="entry name" value="Spore_V_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30029">
        <property type="entry name" value="PTHR30029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04293">
        <property type="entry name" value="SpoVR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="660" mass="76486" checksum="F0F57DEBC0FC566E" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P719</accession>
    <name>U1P719_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01510</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89352">
        <property type="protein sequence ID" value="ERG89352"/>
        <property type="gene ID" value="J07HX5_01510"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465133_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="239"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="568" mass="60301" checksum="0F6CC8987C7574D0" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P731</accession>
    <name>U1P731_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00067</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87926">
        <property type="protein sequence ID" value="ERG87926"/>
        <property type="gene ID" value="J07HX5_00067"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151709_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="119" mass="13527" checksum="716778359B697A58" modified="2013-11-13" version="1">MSETQTVTDTPGIARELSAFQQNILTILAEEARYGLAIKRELESYYESEVNHGRLYPNLDDLVEMDLVEKSELDKRTNEYALTQDGYQALLDQLEWQAGRIITNDDRASDLESVVKAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1P737</accession>
    <name>U1P737_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-aspartate dehydrogenase</fullName>
            <ecNumber evidence="6">1.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadX</name>
        <name evidence="9" type="ORF">J07HX5_01515</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:11788"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:11784"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the L-aspartate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.21" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89357">
        <property type="protein sequence ID" value="ERG89357"/>
        <property type="gene ID" value="J07HX5_01515"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089550_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033735">
        <property type="term" value="F:aspartate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01265">
        <property type="entry name" value="NadX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002811">
        <property type="entry name" value="Asp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022487">
        <property type="entry name" value="Asp_DH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020626">
        <property type="entry name" value="Asp_DH_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011182">
        <property type="entry name" value="L-Asp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01958">
        <property type="entry name" value="DUF108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005227">
        <property type="entry name" value="Asp_dh_NAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03855">
        <property type="entry name" value="NAD_NadX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_3" evidence="8">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF108" evidence="7">
        <location>
            <begin position="177"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="278" mass="28505" checksum="BAD0CD83B5BA4D06" modified="2013-11-13" version="1">MTLHVKLDIGLIGCGTIGTEIATAVHTGRVPNTNLTAVFDIDEEQTKTLVESLDGAPNPVDSVSTLITEADLVVEAAGQAAVQSVAVDVLESNTDLMIMSVGALAETSLRRSVIEAADGESSRLYVPSGAIAGLDAIKAAALANELSSVTLTTRKPPSGLEGAPYIEDNEIDLNGLEEESVIFEGSATEAARAFPANVNVAMSLSLAGIGPEETAVTVVADPDEINNVHQIAAEGSAGRIQTTVQNVPSPTNPKTSYLAALSAIEKLRSITGAVSTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P768</accession>
    <name>U1P768_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pilin_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01545</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89387">
        <property type="protein sequence ID" value="ERG89387"/>
        <property type="gene ID" value="J07HX5_01545"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1631701_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012859">
        <property type="entry name" value="Pilin_N_archaeal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07790">
        <property type="entry name" value="Pilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pilin_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="14577" checksum="4482C5120455116A" modified="2013-11-13" version="1" fragment="single">APVVGTVVLVGATVIIAAAVGASLVTIEPPAPAPTVQLALTADAGADRLTLVHQGGGPLDIKTCELTVRIGGTALTHQPPVPFFAATGFESGPTGAFNAAGSTVLRPGKHASLQLAETNAPTLTPGARVTVRVATDEAVLAELETTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P785</accession>
    <name>U1P785_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01565</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89407">
        <property type="protein sequence ID" value="ERG89407"/>
        <property type="gene ID" value="J07HX5_01565"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="31468" checksum="DA3D9073E9B83360" modified="2013-11-13" version="1" fragment="single">MRDAAFVQQTDPDAVFNLLADETRLSIIRELADADETVSFADLREQVGVRDSGRFNYHLDKLVGQFVRKTDAGYRLTETGDRIDGALEAGTYTLAGSIDSVALTDPCTVCGEEQRLHYEDKMVHSECGCFVKTRFHLPPSAIGEFDPETFPDIADRYLKTTLYQMTSGFCPYCDGQVTAEVGPIVLPEETDELSAAEIERVQDAPHVDFSCTRCDREFGAGLTSALLFRPVVASFYYEHDVDIQTEPYWQLRGLVTDRERIRSQDPFRAAVTYEVNEDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7E8</accession>
    <name>U1P7E8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00207</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88066">
        <property type="protein sequence ID" value="ERG88066"/>
        <property type="gene ID" value="J07HX5_00207"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3093963_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="5339" checksum="484B259A450A7F3E" modified="2013-11-13" version="1">MFPTGSGGCRNQTAGVVAGYGFTLTAVDNNRIEVISVKKTQSTDDAHIRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7K5</accession>
    <name>U1P7K5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytidine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01703</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89537">
        <property type="protein sequence ID" value="ERG89537"/>
        <property type="gene ID" value="J07HX5_01703"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097262_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="144" mass="15491" checksum="BE5EC39E3096FB51" modified="2013-11-13" version="1">METAPLSSEDEALIEHIRQTNERTFDPDFFEGAHIVAAGVRMTDGAVCEGVSLPASVGRASMCAEPVALGSAIADGYSHDDTDTCVAVACPMPSHDTDEPRVIPPCGSCRELLADYNEEMRVIVPINEECRLASAIDLLPTRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7P4</accession>
    <name>U1P7P4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-binding protein involved in rRNA processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00304</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88161">
        <property type="protein sequence ID" value="ERG88161"/>
        <property type="gene ID" value="J07HX5_00304"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165884_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="80" mass="8216" checksum="97C036D21E658E72" modified="2013-11-13" version="1">MNRVGEVVRAAQGLAVIRCASESHPGLGAPLVDEQLTTLGTVVDIFGPVDRPYVAVAPTDSDPAAALGRTVYSKPDLADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7R7</accession>
    <name>U1P7R7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD/FMN-containing dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00329</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88186">
        <property type="protein sequence ID" value="ERG88186"/>
        <property type="gene ID" value="J07HX5_00329"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129570_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-oxidase_C" evidence="2">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="168" mass="18311" checksum="CD4CCC50B414DA50" modified="2013-11-13" version="1" fragment="single">AESGEQMRELWELRGEMARAFESYDPGLTPLTAGDVTVPIGEFSELMSQIAALEADRDVLIPCFGHAGDGNVHYVVMVDADDPDAREHGEQVYGEIVETAVERGGTVTGEHGIGIGKRSYVGEEWGDETVTLMRQLKQTFDPNGILNPGKIFPEGTDAADKDRIDETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7T5</accession>
    <name>U1P7T5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GMP synthase-glutamine amidotransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01792</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89622">
        <property type="protein sequence ID" value="ERG89622"/>
        <property type="gene ID" value="J07HX5_01792"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="224" mass="24496" checksum="6B73E4ADEB4D6C02" modified="2013-11-13" version="1">MTVSIALADASIGESASERNFRRELDATVDAYKISNGELPPPVSTPAWSYDGIVITGSRTSVYDDHDWIDAATDWYRGAHEAGVPTLGVCWGHQFIAQALGGQVAAAGEYELGYTTVEQAADDPDPLFMSVPTRFTAFETHSDEVVELPPGATMLARNEFSLQAFRVDTAWGVQFHPEYDRQTAVEVTTGKNLPQERIQRVLDGVTPEAIXXXXXXXNLQSWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7X1</accession>
    <name>U1P7X1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ammonia permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_00389</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88246">
        <property type="protein sequence ID" value="ERG88246"/>
        <property type="gene ID" value="J07HX5_00389"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="10">
        <location>
            <begin position="22"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="431" mass="45955" checksum="C75165126DD6B5F5" modified="2013-11-13" version="1">MIELSPQLLQADAVETAVSDTWILTVSFLIFFMHAGFAMLESGQVRSKNVANQLTKNLLTWAVGVVVFFLFGIGFANFMAGSLNLSAFESGAPFLDKTPGDAGQYIGWLYGAVFAMTAATIVSGAVAGRAKLRAYIGYTFLLAAVIYPMTIAMTWTGGNVTGSGFVQDLTGTAFIDFAGGMVVHGLGGIAGLTAAYVLGPRMDRYDDDGSVNIIPGHSMSFAVLGTLILSFGWFGFNVGTAGAFDGADVLGRVAMGTSIAMAMGAIGAGLVSRVRDEKVDTLYVANGMLAGLVGITAIPHIATWWGALLVGLLAGAQLPVVFDFVKERLKIDDVCAVFPVHGTAGVIGALAAPFVHFNLGPSIVDXXXXXXXVQAHRPGAGDPRARARWARHLRAWRRDLPRVRWRRSRRAWSNGDRRRRSGSRPPARRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Z0</accession>
    <name>U1P7Z0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative P-loop ATPase fused to an acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00409</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88266">
        <property type="protein sequence ID" value="ERG88266"/>
        <property type="gene ID" value="J07HX5_00409"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132452_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="119" mass="12715" checksum="678E4FDF6F6574BB" modified="2013-11-13" version="1">MLIRETTDDELLGVRRVLNAGALRVPAGLTEATTIIALANSPPILGALVLEGPTITAIAVRPRRRGQGIGTALVEAAAERRVRLVVQFDPSVRPFWAGLGFTIQPAVGDTRQRLRGVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P844</accession>
    <name>U1P844_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00455</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88311">
        <property type="protein sequence ID" value="ERG88311"/>
        <property type="gene ID" value="J07HX5_00455"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3110638_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="6016" checksum="AB3FAC7E64B6995F" modified="2013-11-13" version="1" fragment="single">MLTENTLSALKNTCHYRSPELLRLQVVANHMRIEYDRNTCIGMFQCVAEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P886</accession>
    <name>U1P886_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00490</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88346">
        <property type="protein sequence ID" value="ERG88346"/>
        <property type="gene ID" value="J07HX5_00490"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2983340_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6016" checksum="77BB09D023463B57" modified="2013-11-13" version="1" fragment="single">LDPPHLALVGGDPNKNSLVAQVRHGATSLLFTGDAEQAGERLLVEEHGDTLRTTVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1P893</accession>
    <name>U1P893_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="7">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">aIF2-gamma</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">eIF-2-gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">eif2g</name>
        <name evidence="9" type="ORF">J07HX5_01949</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer composed of an alpha, a beta and a gamma chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89777">
        <property type="protein sequence ID" value="ERG89777"/>
        <property type="gene ID" value="J07HX5_01949"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027154_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
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        <property type="entry name" value="eIF2_gamma_III"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00119">
        <property type="entry name" value="eIF_2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
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        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022424">
        <property type="entry name" value="TIF2_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eif2g_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="32"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="171"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="206"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="436" mass="46247" checksum="D82D27A5937A467E" modified="2013-11-13" version="1">MLVSQPSGKQQLYALQQANIDEITPEMTPNNQPEVNIGLVGHVDHGKTTLVQALSGEWTDQHSEEMKRGISIRLGYADATLRECPDRAAPERYTVAEECPDGTPSEPLRTVSFVDAPGHETLMATMLSGAALMDGAVLVVSAAEPVPQAQTQEHLMALDITAIDNIVIAQNKIDLVDAEQARENYEQIQSFVAGTVAEDAPIVPVSAQQEINIDLLIQTLEEAIPTPDHDADAAPELRVARSFDINRPGTTWDELTGGVLGGSLSAGRLTEGERIELRPGREAETGGQSEWQPMETTVRSLQSGGKTTSEASPGGLLGVGTGLDPALTKGDALAGQVAGTPGTLPPVHESFTMSVTLLERIVGTDADDSEVEAISTGEPLMLTVGTATTVGSVTSARGEECEVRLKRPVCARPGVNIAINRRVGARWRLIGYGTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8P6</accession>
    <name>U1P8P6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02075</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89902">
        <property type="protein sequence ID" value="ERG89902"/>
        <property type="gene ID" value="J07HX5_02075"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
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        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="227" mass="24900" checksum="182415DF52F0EC88" modified="2013-11-13" version="1">MTKTTEAVLFDVDHTICEYHRSTRKLLSLAFDRADVTPFFAVEEYWALYGEYVGESDSIDGLREQCFLELADQNGETRERGRQVAEAYNHVRDHTNVRFLDGAAEALDQLNDQYRLAAVTNGPEDAQATKLDALGVDQFETVVFAGFETPAKPHPAPFEKALAAVDTTPDNAVFVGNSLEADIAGAHAAGLEAAWLRDGAVPVDGPTPEYVLEEPADLLARPWETAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Q2</accession>
    <name>U1P8Q2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative endoIII-related endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00662</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88516">
        <property type="protein sequence ID" value="ERG88516"/>
        <property type="gene ID" value="J07HX5_00662"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="55"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="25849" checksum="23B7CD75F060D5ED" modified="2013-11-13" version="1">MSTDAGSADRWTESQVRELHDELIGLYGPVERSDGDGAHGGEPGEGVRQLLTTILSQNVADQNTRRAAEALFDQYAGFDAIERADHDELADTIRVAGLPDQKASRIQRSLAAVREETGGAYSLAFLEAMATDDAKSWLTDIKGVGPKTASVVLNFHFGKPTMAVDTHVERVSKRFGLVPESATNKRAHKVLDGIVPDELTYPLHVLLIRHGREHCSARNQDCSNSVCDRYCACAVCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8S7</accession>
    <name>U1P8S7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">His Kinase A (Phosphoacceptor) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00687</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88541">
        <property type="protein sequence ID" value="ERG88541"/>
        <property type="gene ID" value="J07HX5_00687"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="343"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="545" mass="59178" checksum="B877629F36E0067A" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9E9</accession>
    <name>U1P9E9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translation initiation factor 1A</fullName>
            <shortName evidence="3">aIF-1A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">eif1a</name>
        <name evidence="8" type="ORF">J07HX5_00907</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 3 6">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the eIF-1A family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88761">
        <property type="protein sequence ID" value="ERG88761"/>
        <property type="gene ID" value="J07HX5_00907"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109098_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="PTHR21668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="11151" checksum="7D365B656D110818" modified="2013-11-13" version="1">MSDSKSKTNLRMPDDSEVFAVVTEMLGANRVAVRCMDGVERTARIPGKMQKRIWIREDDVVLVEPWDWQDEKGDISWRYEKQDADQLREEGHIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9I0</accession>
    <name>U1P9I0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00932</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88786">
        <property type="protein sequence ID" value="ERG88786"/>
        <property type="gene ID" value="J07HX5_00932"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1217545_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="25587" checksum="1C066DCE47220FBA" modified="2013-11-13" version="1">MVYESDMIRDLTTAVRQRVSRTTVALWALTLCAVYFFTGDIALVAGIMIAYLFIGGMDLLGDVPGVDERWVKAAVPVVVGAVSGVWLWLELSSPATGDVWPPVLALVACLWLALDVRANFVQDRRLGRTDEFDDLSSAEAVLVMQHGHLVADHLQDGPMTVDELAAACDLTVSRVEEVIDLFGRDGSIYPVDSDAEHPRYALDEQRIGLSGLGRQAAGGLSGLISRLLRPFTEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9U1</accession>
    <name>U1P9U1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01002</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88856">
        <property type="protein sequence ID" value="ERG88856"/>
        <property type="gene ID" value="J07HX5_01002"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035788_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019293">
        <property type="entry name" value="ThiN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10120">
        <property type="entry name" value="ThiP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="2">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="472" mass="48245" checksum="548BB5873C20CAC5" modified="2013-11-13" version="1">MSRQPDPVSPPVVTTIAGSDSGGGAGIQADLKTIEAEGGFGTSVVTAVTAQHTRGVERTHMLPLEEIRAQLAAVTDDFSLGAVKTGMLGTRSVVEFVTEQARSVQAPVVVDPVMVAASGDRLLNSAAEEAYQALLTEATVVTPNAPEAAVLTDVSVTDAETARTAGEQLVAAGADAALVTGGHTADETVLDVLVTDADTTEFRHPRVGADAVHGTGCALTAAVATRLAHGDTVTDAVSHGIKLLERAVQYPIAVGGGADVVHHAVGLRNRAECTTAVEAVRTLRDRLSDDVDAIARLVPAAGMSVVAATPYAEHTDECAAVEGRLARADDGVRAGEARLGASTHAAQMLLSARTVTPGLRAGISCQFDETVEQAVSELGWTVTETDQPDGVQTEDGRTAGLTATATELTEALDGEQPGQPSADSPLVVVGRGAGGTEPTGLVLTGSTEQLVTELSKLSQTVQDDIGHPTNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA31</accession>
    <name>U1PA31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01111</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88961">
        <property type="protein sequence ID" value="ERG88961"/>
        <property type="gene ID" value="J07HX5_01111"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3243434_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043825">
        <property type="entry name" value="DUF5802"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19118">
        <property type="entry name" value="DUF5802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="43" mass="4564" checksum="376DE5E3C016055E" modified="2013-11-13" version="1" fragment="single">PPTVLEETSIRNPPTLTEVFLATADRAAQLLSLSRPAGTARDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA36</accession>
    <name>U1PA36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative PP-loop ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01116</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88966">
        <property type="protein sequence ID" value="ERG88966"/>
        <property type="gene ID" value="J07HX5_01116"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1381418_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="197" mass="20848" checksum="7F4E281306FE26F4" modified="2013-11-13" version="1">MEVGLLYSGGKDSTLAALVLEPFCSVTLLCGTFGATDDYEHAMATASAVGLPARRLTLDPTVARAAAERIVTDGYPRNGIQQVHEHALERASATDVDGVADGTRRDDRAPTVDRSLAQSLEDRHGVAHLAPLAGMGRSAIDTFVEAALVVETGPSEAIEAGDYEGELRALIARKHGRNTVDQVFPEHSQSQVTGRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAF0</accession>
    <name>U1PAF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative hydrolase/uncharacterized protein, coenzyme F420 biosynthesis associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01228</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89076">
        <property type="protein sequence ID" value="ERG89076"/>
        <property type="gene ID" value="J07HX5_01228"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059556_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022454">
        <property type="entry name" value="CHP03883_F420-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018766">
        <property type="entry name" value="Zinicin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042271">
        <property type="entry name" value="Zinicin_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39420">
        <property type="entry name" value="PTHR39420"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10103">
        <property type="entry name" value="Zincin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03883">
        <property type="entry name" value="DUF2342_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03624">
        <property type="entry name" value="TIGR03624"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="35109" checksum="775DB79D80D9080B" modified="2013-11-13" version="1">MSIYESVRAVTGASGDGHVDWGAVTQAARASTTPGTVNVDAAEREAYTTDVRDARDRVRSVTGLKFDLPDQIEVQNRHHWLTANIGTFERVLGPLEQEVGQIPGIARVLNTGSMAVSLSYLSQQVLGQYDPLLLAQGDAHALYFVRPNIVRAADSLGVPYDRFRRWIAFHEVTHAAEFGAAPWLPAHLEERMQHAVSKLAAGSIDRGALNKLNVTMTAVEGYAELVMDRAFDEKYADLRQKLDERRQGRGPVEQLLRRLLGLSVKRRQYERGKSFFDTVVEARGLPAAGRVWDGPETLPTDDELDDPHAWLERVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAG0</accession>
    <name>U1PAG0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01238</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89086">
        <property type="protein sequence ID" value="ERG89086"/>
        <property type="gene ID" value="J07HX5_01238"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078424_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="29751" checksum="61BBF1BCD6267AC4" modified="2013-11-13" version="1">MTIGNAEQTKTGPSLRALAKVVIHKKLVLLLRYPVNTGTQFITMIIFFILIFFGGQQVAGPGIDDSLNGIIVGFLLFTLTTVAYSSLSYQVTREAQWGTLERLYISPHGFGTVMGLKTIVNVIMSFCWGLLLLVVMMGITGRWLTLDPLIVVPLVVLALMSVVGVGFLFAGLAIVYKRIENLFQIVQFSFVGLIAAPVGQIEWLKLLPLTHESYFLRRAMEDGIPLWEVPQTELGLMICTSVVYLVAGYYCFYRASITARKRGVMGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAG5</accession>
    <name>U1PAG5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="3">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01243</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89091">
        <property type="protein sequence ID" value="ERG89091"/>
        <property type="gene ID" value="J07HX5_01243"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050228_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="PTHR43607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="8">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_Xtn" evidence="9">
        <location>
            <begin position="95"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="169" mass="17929" checksum="6C8434F6B16551CA" modified="2013-11-13" version="1" fragment="single">MSKTSDGTDETVREDGQIESVSGPVVTATDLETRMNDVVYVGREGLMGEVIEIEGNLTTIQVYEETSGVSPGEPVETTGAPLSVDLGPGILDTVYDGVQRPLDVLEDTMDSAFLDRGVDAPGIDLEQTWEFTPTVEVGDTVESGDIVGTVPETESIEHKVMVPPDVEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAK6</accession>
    <name>U1PAK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR00162 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01284</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89131">
        <property type="protein sequence ID" value="ERG89131"/>
        <property type="gene ID" value="J07HX5_01284"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075000_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004426">
        <property type="entry name" value="CHP00062"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00162">
        <property type="entry name" value="TIGR00162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="250" mass="26597" checksum="0DE1A645D7FF4115" modified="2013-11-13" version="1">MDEFEVERTGAIDGLTAPVLVEGLPGVGHVGKLAAEHLLDEFDSELVRRIYSTHFPPQVGVTDGLTQLASAELHVIKTEKTDILVLTGDHQAQDTVGHYGLADTVLDIADIAGVSDLYTLGGIPTGELIEEYDVVAAATTEAKQDELGELVEFRGSEPAGGIVGVSGLLLGLAERRAVPAACLMGETSGYLVDPKSARAVLDVLQDVLAIEVGFDSLEDRADEMEQVVRKIQEMDDDSAAPTDENLRYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB43</accession>
    <name>U1PB43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01459</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89301">
        <property type="protein sequence ID" value="ERG89301"/>
        <property type="gene ID" value="J07HX5_01459"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1507332_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="178" mass="19986" checksum="6D46B8A03C385810" modified="2013-11-13" version="1">MGLPGFALPQESPTPVPFEERAFSGGFHTGSRRDLFTVPDFGAGRQTARLTDYFWAYETSLNKILEPKYPSRFLPRRTPLASATTLRLRWLWRGLSQLRLASCSSAQSDILPRLKPWGSXXXXXXXRTTETEVCHVGSFRGSLRVVAPKRPDTRRSKRTRGTDDGTPSLVEVITQTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB49</accession>
    <name>U1PB49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01464</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89306">
        <property type="protein sequence ID" value="ERG89306"/>
        <property type="gene ID" value="J07HX5_01464"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="167"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="380" mass="40462" checksum="AE8DF6A549C44A34" modified="2013-11-13" version="1">MYTYPTVAYPVAATSAQQMLAVLFRGLEAKQGNMTRESTDVRSVPIDRYPGPACSYRFVDGNPVLTATNDSFAEQIDGGADGAALAAVFDRLGGRVRGDTASLSACLADGTPFRIQFYPDTVPAAEYLVQTVAPTDDEPGFLMFVEQPATAEREVSSALGIDHVASVVSHDLRNPLDVAKARLQAGRELDEDEHFDHVEQAHKRMERIIQDVLTLARGEEVIDPDEVVDLTAVATGAWETVETNGAVLTTDDQLPTATADADRVSRLFENLFRNAVEHAATEPTPTDIRDDGVKTAPVTVTVGCLDSNGIDGFYIADDGPGISPADHARVFEPGYSSDEHGTGLGLAIAARIADLHGWSVAVTQSADGGARFEVSGVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBH4</accession>
    <name>U1PBH4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01579</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89421">
        <property type="protein sequence ID" value="ERG89421"/>
        <property type="gene ID" value="J07HX5_01579"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1079627_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="28271" checksum="0A2CC005C11A7EF9" modified="2013-11-13" version="1" fragment="single">DAAPDSGRVQVFDQYSPSDRPARLQSSVLLQGRTADPGLTGRENIAFYGDLHPQWTDRWQELVERFNLAAELDRPVAEYSGGMVRKLELAIALTPDVPLYLLDEPTAALDLSIMTTVRSVLADIRAAGRTVVLASHAPQDAELADRIAFVARGTIVAEGTPESLRASVPPVVRAVSGTHMSAVLPEERVFTDGAEQRGFLTMKSDEQFSDRKTIQSETSLEIVEPSYTDVFNYYAHVVRQDESDFTGHGAVRRQSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBJ6</accession>
    <name>U1PBJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01605</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89446">
        <property type="protein sequence ID" value="ERG89446"/>
        <property type="gene ID" value="J07HX5_01605"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1922699_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="134" mass="14541" checksum="504D76EC598ACFB2" modified="2013-11-13" version="1">MTNNDHKLEDDGAVTADQLDVTSSEAVQELDEHRHVINTADEQTPPDADQATAERQSASLPPGAYSLSARGRSQDMTDVFTTGTNNVAATFEQLIIWYARLVAPDRPPEETITALLSHSEITPXXXXXXXSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCC8</accession>
    <name>U1PCC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01918</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89746">
        <property type="protein sequence ID" value="ERG89746"/>
        <property type="gene ID" value="J07HX5_01918"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="23972" checksum="A79966F0B871C0E2" modified="2013-11-13" version="1">MDGETAVITGASRGIGRAVAELFAEAGARVVICARSRDKLETVAETIRDDGGTATAVQADVRDEFDVERLMQQAVAGGSVEYVIANAAVYHGESGETPLHDESYSVYDNTLRTNGRGVFTTLKEALPHLASDGRILVSSGSVARTAYPGYGAYAVSKATAEAVARGVAADVDHVVGIVDPGRVATELTGADAYDPEDVAPQFRWAATEAPADDVDGQVVDRGDWRKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCI8</accession>
    <name>U1PCI8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01978</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89806">
        <property type="protein sequence ID" value="ERG89806"/>
        <property type="gene ID" value="J07HX5_01978"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081974_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="91" mass="9979" checksum="B4039F5A0F9CC9DC" modified="2013-11-13" version="1">MAETLSEEELATQLPEGWGRDNNEIVRTFEFDAYLEGAGFAAGAAGIAQEAFHHPEITISWREVEVRLTTHDAGGITKADTSLAARLNELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFK9</accession>
    <name>U1MFK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00050</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87909">
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        <property type="gene ID" value="J07HX5_00050"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_807993_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
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    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GAF" evidence="4">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="BAT" evidence="5">
        <location>
            <begin position="125"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="286"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="343" mass="37861" checksum="5362C8A18CB9EDAF" modified="2013-11-13" version="1">MTPQAWAGDGQKYLDELTTTTGADSRQRTVGLAARVIETRETQFVDNLANNPALEPWQKTALNNGYRSVLSVPVVYEGSAYAVLEVYADRPSAFGGDEREVLTELGQTIGHAINAIQRREALVADHRTELDLRVQTLDNILFQMTSSIGSTIDIETVLPQSNNNCVLFFTVDTDAASEAIAFEDQSVNISGMSRVRDQGDSVQFKCTVRQPELITTISQQGAQIQSISVNGSEGSVIVQVSQSQNVRSFVTALESTYPDIELVARRKQTQSEQGTGPIRERLDETLTERQLEVLQVAYSAGYFEWPRENNGADLAEMLDIAQPTFLQHLRSGEQKLLSALIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFR2</accession>
    <name>U1MFR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00135</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87994">
        <property type="protein sequence ID" value="ERG87994"/>
        <property type="gene ID" value="J07HX5_00135"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2874942_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="63" mass="6772" checksum="DD9BBBBE9E3D4FCF" modified="2013-11-13" version="1">MPDNLSEDVWSDDLGRPAYENLTHGAQRLLHSPSRCATILTAFGCSTSVVSTLTVAARSGTHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFS0</accession>
    <name>U1MFS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00145</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88004">
        <property type="protein sequence ID" value="ERG88004"/>
        <property type="gene ID" value="J07HX5_00145"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893097_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="7397" checksum="039DF18D76E0806E" modified="2013-11-13" version="1">MPRDRTDDLVFRDDERQRLSNHLTPWRKPTLDDTNNLNSKADSASYYMNIHNAMSLNIKYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFU6</accession>
    <name>U1MFU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00180</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88039">
        <property type="protein sequence ID" value="ERG88039"/>
        <property type="gene ID" value="J07HX5_00180"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942008_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="83"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="32015" checksum="3FB2A7801E2882F9" modified="2013-11-13" version="1">MSGPEESIRERITAQFSYLSDRADIWRGLDLLLETDAYLNLGYSRWYQTHLLGAPQRRLTEHVGRRLAEHGLGAGPGATPRPILDIGAGRGGPAVTLAERFDGGVLGVDLVRYNARQTRVVAREQGVGTRIEALVGDATELPVASGIIAGAVAIDAFVYLPDRSAAMTELSRVLAPTGVAVVSDLVTDEAAPGAAKIPAFADAWDLEPPGTVDEYTQLAADAGLELVTIEDLTAHSVGRFRGWAGLYLRLIKSPVGTLLERWLTAQGLDPTAITTQIRCAHAALPALEHRLFVLRRPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGC3</accession>
    <name>U1MGC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dTDP-glucose pyrophosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00402</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88259">
        <property type="protein sequence ID" value="ERG88259"/>
        <property type="gene ID" value="J07HX5_00402"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="239" mass="26636" checksum="14C4ABD970694BC6" modified="2013-11-13" version="1" fragment="single">AAGKGTRLRPLTDDKPKALVEVNGTPLIEDVFDNLIQMDVEEIIVVVGHMKEQIIERYDDVYRGVPITYTHQRKQDGLAHALLTAESHVEDDFVLMLGDNVFRANLGDVVNRQRESRADAAFLVEEVPHEDASRYGVCDTNDYGEVIEVVEKPNDPPSNVVMTGCYSFTPKIFHACHLVQPSGRGEYELSDAIDLLIQSGRTIDAIPMNGWRIDIGYPEDRDQAEQRLQDSAGGQIAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGC8</accession>
    <name>U1MGC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosine/adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00407</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88264">
        <property type="protein sequence ID" value="ERG88264"/>
        <property type="gene ID" value="J07HX5_00407"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15307" checksum="10B6B15B8FF6DA13" modified="2013-11-13" version="1">MPTDTDADHLRAAIDCAEASPDGHPYGAVLVRDGTVLRDAKNTVPTDGVTAHPEFKLARWSADALAPEARAECTMYASTEPCEMCTTTIGYAGIGRVVFSVTRATLASRHGSAAGVPCRELLDRKGAPTTVKGPMLQDEGLVVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGK2</accession>
    <name>U1MGK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diketogulonate related aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00488</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88344">
        <property type="protein sequence ID" value="ERG88344"/>
        <property type="gene ID" value="J07HX5_00488"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="21"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="280" mass="30902" checksum="714E49E481FE856E" modified="2013-11-13" version="1">MNADERPRPEHVPTSNTMPMLGLGTWENADYDQCVKSVRTAIDTGYRHIDTAQIYRNEEAVGEGIATADTDRDELFLATKVWISNLNPTAVRESTRASLDRLGVETVDLLYVHWPAGEYEPAATLGALEAVFEAGLTRRIGVSNFEPNHLDRARELCDVPVFANQIEIHPYLPQEALRAYADRTEIELVAYSPLARGAVLDDPTLTAIAADHDASAAQVALAWLRSLGITPIPKATSPAHIRDNWASLTVDLTAEEIARINAIDRTDRRVHPDFAPAAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGQ0</accession>
    <name>U1MGQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00529</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88384">
        <property type="protein sequence ID" value="ERG88384"/>
        <property type="gene ID" value="J07HX5_00529"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127458_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="60"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18960" checksum="7DFE3E5B56AD9118" modified="2013-11-13" version="1">MWARRKLADRETHFYHTLTDAIITECVERGVGTLAVSWPENVRESDWGKTGNKKLHSWAFDRIFQYLAYKGKVRDVEVLKKNEWSTSKTCSKCGDDAKSNRVERGLYVCSSCKLVANADCNGAENMRQKITPSPHGEDRSNGCVAQPSTYLFDRESGTFNTREQVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGW6</accession>
    <name>U1MGW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00629</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88484">
        <property type="protein sequence ID" value="ERG88484"/>
        <property type="gene ID" value="J07HX5_00629"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1091896_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="1">
        <location>
            <begin position="61"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="28122" checksum="5F98CD57CB62EB46" modified="2013-11-13" version="1" fragment="single">MRLSGCASSTVTAAVTCSSPAASPPRLSLRSQQLSTRSWSPGVVITRALPASATQPFGRRSQDADIDRESVHDAVHHKPGEITTNSGDPYKVFTYFSRKWHDREKRPAADPTASFVSTGSAVTAAVDAVQASVPTRSELGVDAPEAEIPPAGTETARELLESFCAADIYRYDDRRDYPADDCTSRLSAHFAHGTIGVREVYARTERAKAAAETEAEQDSVEEFQDQMAWREFYTQVLWDRPDVVTENYKEYENPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGZ1</accession>
    <name>U1MGZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00670</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88524">
        <property type="protein sequence ID" value="ERG88524"/>
        <property type="gene ID" value="J07HX5_00670"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3417780_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="26" mass="2964" checksum="04F3438BD6B9DCA0" modified="2013-11-13" version="1" fragment="single">MYSPDVFPVMARWECAIEGDDRGGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH01</accession>
    <name>U1MH01_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase II small subunit</fullName>
            <shortName evidence="12">Pol II</shortName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Exodeoxyribonuclease small subunit</fullName>
            <ecNumber evidence="12">3.1.11.1</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">polB</name>
        <name evidence="15" type="ORF">J07HX5_00685</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11 12">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EC" id="3.1.11.1" evidence="12"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88539">
        <property type="protein sequence ID" value="ERG88539"/>
        <property type="gene ID" value="J07HX5_00685"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027850_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008852">
        <property type="term" value="F:exodeoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000738">
        <property type="term" value="P:DNA catabolic process, exonucleolytic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00325">
        <property type="entry name" value="DNApol_II_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011149">
        <property type="entry name" value="Pol2_small_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="PTHR10416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000803">
        <property type="entry name" value="Arc_Pol2_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_E_B" evidence="14">
        <location>
            <begin position="265"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ERG88539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="517" mass="55891" checksum="3432F50C89972B27" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH14</accession>
    <name>U1MH14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00705</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88559">
        <property type="protein sequence ID" value="ERG88559"/>
        <property type="gene ID" value="J07HX5_00705"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129106_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="13592" checksum="61F99D73867A2EFF" modified="2013-11-13" version="1">MTTEQTLVKTLDFQLDIQSDNESLLYDVTLEARRAYNETIRLVKQGADWDAIPDRVADDANLVKNTTQRVVAKALGAMENYYEYDDFGQPSHTKDGAYPLRANYEEGYNLSLTDDGDVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH76</accession>
    <name>U1MH76_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00795</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88649">
        <property type="protein sequence ID" value="ERG88649"/>
        <property type="gene ID" value="J07HX5_00795"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2730190_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="71" mass="8273" checksum="67C2636A374FC6A5" modified="2013-11-13" version="1">MTSQIELVLFAVYPIPFSFVIGFFLSKLNIRLLAVYGGEEWFPDRVVQVVEKYRDENNVDPDLDTEMQSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH91</accession>
    <name>U1MH91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Superfamily II helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00815</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88669">
        <property type="protein sequence ID" value="ERG88669"/>
        <property type="gene ID" value="J07HX5_00815"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000335_0_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="48"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="43112" checksum="EBCF79D400825CEF" modified="2013-11-13" version="1" fragment="single">MCVLLPSCIVSETSGGPEPTVPVSEVLPEFASVFPFDEFNSMQSATLPAVLGTDENVVVSAPTASGKTAIAEAAIVRTVADGGTALFLAPLRALTNEKEREWERFEALGYSVYVVTGERDLDPRRAEQADVLVMTPEKADSATRKHDSRRYAFVSEVDLCVIDEVHLLDSEKRGSVLEVTISRLCRLCPQLRIIALSATMRNVGDVAAWLDAPEETTFSFGDEYRPVPLEASVATYTHGENPFADKYRRLYRALDLAEPHVRDGGQALVFVASRQDTVQAAETARDELASRDVPVGARGELDWHDETDTLANDTLRQSVIDGVGFHHAGLSRDDKDRVEAWFRAGRLAVLFSTSTLAWGVNLPARCVVLRDTYHHDPLEGEVEMSHLDVLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHA8</accession>
    <name>U1MHA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00840</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88694">
        <property type="protein sequence ID" value="ERG88694"/>
        <property type="gene ID" value="J07HX5_00840"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112916_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5453" checksum="23EEB2EF6C476F10" modified="2013-11-13" version="1">MEPLAAICVYGVLNRWSDSMMTDLEDGPCGLADRVLDDRGGGKHVDDRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHC0</accession>
    <name>U1MHC0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA primase large subunit PriL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">priL</name>
        <name evidence="10" type="ORF">J07HX5_00855</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of a small subunit (PriS) and a large subunit (PriL).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88709">
        <property type="protein sequence ID" value="ERG88709"/>
        <property type="gene ID" value="J07HX5_00855"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052778_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06560">
        <property type="entry name" value="PriL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00701">
        <property type="entry name" value="DNA_primase_lrg_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023642">
        <property type="entry name" value="DNA_primase_lsu_PriL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0639">Primosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="380" mass="40902" checksum="3ACC25D0D1604D31" modified="2013-11-13" version="1">MSIEPRHARYPFTEAARAAVEAADADLAGIVEHGGPVVERAVDRVDRAVETGAVGSPHRRPRIELLSYPIARVLVSLVDEPGLTRKYARAEAATAADRFRADIGDAGVTLKSSQTDPMSLTDLLAEFDLDTAVERTTPDDTARYQVAVGAYLKLAADRQGDAWRLVNRQLSNGVVPVEKDELLSLLETAVRERVAAELPLSVPEPIAAALTSEHDRLRQGLADHDLPRDLDTVVPALFPACIQTLIEQCHSGDALSDHARFAVVTFLTSIGLTPDEIVELLSLSGAKAELTRYQATHVRGDAAAAQYAPPSHVTLRSTDVYTEVETDTDTDADVQAETGDPDKHPLVTYAAALAAADQHDLTDWRDRGSEPDAGTETGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHV1</accession>
    <name>U1MHV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01045</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88899">
        <property type="protein sequence ID" value="ERG88899"/>
        <property type="gene ID" value="J07HX5_01045"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2021435_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="14194" checksum="31ABBBC50EDA8623" modified="2013-11-13" version="1">MATPSFAIPARPERRFHRDGVEYEGELLFVCSPATDRSADQLEELVVTVLADGPYRYGDFLDLPMALYLARDDETGDVFRISVRNETVRLHVLPTTEASGLRAFYRRLVDRSTVDWRVDRQTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIE5</accession>
    <name>U1MIE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01317</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89164">
        <property type="protein sequence ID" value="ERG89164"/>
        <property type="gene ID" value="J07HX5_01317"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3263658_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4689" checksum="FF9F953DC4A142DC" modified="2013-11-13" version="1">MLRPVVTALADCDTRRANEFMYTQVRLKPKQCLRIGTSFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIH1</accession>
    <name>U1MIH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sua5/YciO/YrdC/YwlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01353</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89199">
        <property type="protein sequence ID" value="ERG89199"/>
        <property type="gene ID" value="J07HX5_01353"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="21177" checksum="B727A26D2254B9F5" modified="2013-11-13" version="1">MIDAIDRATDTVAGGGLIAYPTETVYGLGADATNPAAVERVFEAKRRSHGKPVSMAVPDIDQAAEHVRLSRRERRFANAFLPGPVTLVCARREGVPDILTAGRDRVGIRIPDHRRALALLARTPPLTATSANVSGRPSALRADELDSEIRAVTDVVLPREMPPADEDPVGSTVVDVARGEIHREGAQGAAVEAWLETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIL4</accession>
    <name>U1MIL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01410</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89254">
        <property type="protein sequence ID" value="ERG89254"/>
        <property type="gene ID" value="J07HX5_01410"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3162971_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="47" mass="5204" checksum="EF5E6412BD3EF942" modified="2013-11-13" version="1">MFELHKAAAGYDLALLGQSQRDIQQRVFGPVADYVAESNEVAVLIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIN4</accession>
    <name>U1MIN4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="12" type="ORF">J07HX5_01436</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89279">
        <property type="protein sequence ID" value="ERG89279"/>
        <property type="gene ID" value="J07HX5_01436"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="287"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="9">
        <location>
            <begin position="256"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="656" mass="74653" checksum="A77A632CCF2B2659" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ49</accession>
    <name>U1MJ49_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpF</name>
        <name evidence="6" type="ORF">J07HX5_01635</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89474">
        <property type="protein sequence ID" value="ERG89474"/>
        <property type="gene ID" value="J07HX5_01635"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076364_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="96"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23139" checksum="8A07B5CB2784473E" modified="2013-11-13" version="1">MLVQLYSLTHPDDIQALVELGVDRFGFAVGDQGLPAEVPLERAHELFALVPDDRTTTVLSVHTAPAEAAAFARRVRPDLLHRCPPPGTDDPTDLRALASALPADVALMTAVAVGTDTAAIDRAAAVATHSDALVVDSAAPDIPGVGATGESHDWSVSRRIVDRVDVPVVLAGGLGPDNVAAAIRAVRPAGVDSYTRTSRTDRRKHIDRTRAFVQAARAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJA5</accession>
    <name>U1MJA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01715</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89549">
        <property type="protein sequence ID" value="ERG89549"/>
        <property type="gene ID" value="J07HX5_01715"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109676_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="74"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="179" mass="20786" checksum="0FDF90FC341E797D" modified="2013-11-13" version="1">MVRRNVPESKEELLELETRKEIFEYVQANAGVHFSQLKRDLEMETGLVQHHLSTLESYNVLTSDDHQGKRRLFVAEELTEEERAILSSLRYETTRHILLFLLEETTARNRAIAEELGVSPATVSWHVSRLVENGIVSEVQDGRTTYYTVADETLTMQLLVRYQESFVDRAVDRVLDFWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJX2</accession>
    <name>U1MJX2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01976</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89804">
        <property type="protein sequence ID" value="ERG89804"/>
        <property type="gene ID" value="J07HX5_01976"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1890012_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="13857" checksum="9855B03EBA8D822B" modified="2013-11-13" version="1" fragment="single">MTARRTFFIDAGGSSARCHKQVVSVGERAVAGVRVDGSWALYTAQWGGADRVVARVLAAGTAGRGAARESTVGLDRLGVVASLAWRPAGTVTGALVEAVDYLETAAVYVIGSATTVWQPLWLGFPGAEPSPSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK22</accession>
    <name>U1MK22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02031</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89859">
        <property type="protein sequence ID" value="ERG89859"/>
        <property type="gene ID" value="J07HX5_02031"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353119_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="9946" checksum="22F07FC56E373024" modified="2013-11-13" version="1">MSRYVVQRSLCMAHETVVTGGVMMLVLLSGVGGVTAILGVVVTDVQQLSFGETNFEPSELIIRSGPAQVRCCGTIYHPACNSEAANGTGDDSLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV11</accession>
    <name>U1MV11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00046</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87905">
        <property type="protein sequence ID" value="ERG87905"/>
        <property type="gene ID" value="J07HX5_00046"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16952">
        <property type="entry name" value="Gln-synt_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="108"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="445" mass="49523" checksum="181C661FD3B81269" modified="2013-11-13" version="1">MTQSEVIEACKQDDIELVRLLHSGYAGMVRGRTKHADDIEDVLEGGTNMAKVVQGFTPFNTPTEGSQHGPMGEIRLIPDADTFQRLPYAENTAVMLCDKYTVDRERWDADPRTALGNFIDELQYTPMTAYESEYFLIKETEDGYEQFDSTQCYTADGMQSAHEIIIDTVRALKAQGMSLDVYYAEGGFGQQELVVNPSRGVQAPDNHVLYRQTAKAIAAEHGVKASFLPKPFQDDFGSGCHMNVSLWDGDSNAFYEEGSGPYGITDTCRYFIGGLLKHARALVALTAPSVISYKRLQPHSWSGTFTAWGYDNREGFVRVPSTQWEDPESTARIELKASDNTANPYLSLFGILAAGKDGIEREIDPGEPLDGDPGALTQQERDRRGIERLPETLGEALDELETDEVLTGKLGKSLIEGYVAEKRTEWNNSKRTVSDWDIDTYGPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV65</accession>
    <name>U1MV65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00121</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87980">
        <property type="protein sequence ID" value="ERG87980"/>
        <property type="gene ID" value="J07HX5_00121"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3227690_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="43" mass="4603" checksum="036B39BE6D428A49" modified="2013-11-13" version="1">MTNAGEMRDFKLGTLPEGITTELGEDPDIVTVASSVRNLSHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV72</accession>
    <name>U1MV72_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00131</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87990">
        <property type="protein sequence ID" value="ERG87990"/>
        <property type="gene ID" value="J07HX5_00131"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2745698_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7360" checksum="09EF84088484068C" modified="2013-11-13" version="1" fragment="single">ASVAHICCLSQQGVTDTSADSGISLRLAQTNTHNMNVSSIRVHQVGIPDIVSLLAGRPLPKAVRNRSVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVC4</accession>
    <name>U1MVC4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00044</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87903">
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        <property type="gene ID" value="J07HX5_00044"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1064042_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="28716" checksum="77C8508249D103F9" modified="2013-11-13" version="1">MRVNVLGAGNPQVAVVGAIHGDEPSGAHAIERFLSEEHNVQRPVKLIILNEPALEQNTRYIDVDVNRVLPGDPTGDQYEERLAYDFIQEIAGCVGMGIHSTFSSAQPFGTIANPNNRKRRLFDSLSGFHHVVDFTQISSGSRGVDLPWYVDVEAGLQQSNTAAENAYECIIDFLSFTGVLEATVSETNTREYEVFETVWKEPDSEYHFDATNFRRVAEGEVYATCNGTEIVADRPFYPVLFSDDGHESIFGYKTALQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVD3</accession>
    <name>U1MVD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00206</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88065">
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        <property type="gene ID" value="J07HX5_00206"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982141_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="28046" checksum="7D3B026F6983975B" modified="2013-11-13" version="1">MAFGIDIPVSENVSLTVAVALLLFGVGLGYTIQRRITARLVSYGVPGIVEGTPFERWARRVGTSTVGIVATLTTAFVYVGVVALSLQVTRLLELRVFWTQLAGYLPRLFVAVIAVIVGLVGGDKAAVAVQERLESVKLPQVGFLPELVKYSMFYITALIILSQIGIATHALLILLAAYTFALIFLGGIAFKELLAAGAAGIYLLLSEPYAIGDEVRVDNRRGIVQEVDMLVTRIETDDEEYILPNHKIFHSGIVRIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVL8</accession>
    <name>U1MVL8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00154</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88013">
        <property type="protein sequence ID" value="ERG88013"/>
        <property type="gene ID" value="J07HX5_00154"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="35719" checksum="D542B06219D1408F" modified="2013-11-13" version="1">MSKKGSSPAIDATGVIKQYEGESGTVTAVDGVSLSISPGEVVGLLGPNGAGKTTAIKCLLGLIVPDAGTVRVCGIDVAAQPDRAHGRVGAMLEGERNVYWRLTVRENLEFFTGLGGRQPAALQERHDRLLDRFDLVDRADSVVNELSTGMKQKVSLASTLARDVDVIFLDEPTLGLDVETALDLRAEIQRLADEENVAVVLTSHDMDVIEAVSDRVVILQDGRIIANDPVERLVELFETQSFRIAIATPVDTRVQRRLDGLGLDVSREGSRLIIQSNGTDSQTIYELMRLLDEPARSCAISTXXXXXXXRTCLNTQPIGPASNLEPMPTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVV6</accession>
    <name>U1MVV6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00251</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88108">
        <property type="protein sequence ID" value="ERG88108"/>
        <property type="gene ID" value="J07HX5_00251"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060475_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="33192" checksum="3B14C50B9C47257F" modified="2013-11-13" version="1">MTEDTAGEDRLDAVPQARDSAAMFSLLGDEVRLEIITTLHEGAPLSFSDLYDQMTLGDTGQFNYHLSRLRTHFVRKREDTYVLTAAGQRIARAVAAGFYTDAPEISPFEIDGACTTCDTAALVASYADERFRIEYAACEVVVVRVSVPPSLVRGREPAAALEAFERWASSQLSQARRGLCPDCGGWIDRTITTETPPETPFAVLPRFACGVCGRDVITSFGALAVRDERVQSFHRRHGVALDDRRYWEIDQFVTDEYTKILSEAPLRVQVRFAADDEVCRVVLDDDHEVRTVEVVSDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVX3</accession>
    <name>U1MVX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00271</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88128">
        <property type="protein sequence ID" value="ERG88128"/>
        <property type="gene ID" value="J07HX5_00271"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053163_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="31026" checksum="4D2BB50ECD4BE64F" modified="2013-11-13" version="1">MDIVVTGGRGQTGRWVLDRLADAHSVSCLDRELPEAGHPLVDYRAVDLTDAGSVLDVMTQLEPDAIVHWAAIPVAGQHAGVDLYQNNTLAAHAVLTAAGRIGADVVQASSDGAYGFFFAAETPVPEELPVPESHPLRPEDPYGLSKVVTEEIGATIARRDGVSVVSLRPTWIQEPGEYPCRDDGYVENLAAGAGNYWSYVDVRDVVDLVVAALQADLTGHEAVNCAAPDNALGRDLRELMRAHYDALPADCTVAGDAAAYDTTKAADLFGWEPTRSWREAAEEDVTPPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVY1</accession>
    <name>U1MVY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00281</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88138">
        <property type="protein sequence ID" value="ERG88138"/>
        <property type="gene ID" value="J07HX5_00281"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_11_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="493"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="368"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="594" mass="63342" checksum="C76E12C3AAFD8CDA" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVZ0</accession>
    <name>U1MVZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CopG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00433</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88290">
        <property type="protein sequence ID" value="ERG88290"/>
        <property type="gene ID" value="J07HX5_00433"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3161267_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="48" mass="5830" checksum="388BEB52FA490F3B" modified="2013-11-13" version="1" fragment="single">MRTSFSIPDEVVEEFDRVWNEQDIENRSRAVREAMLEYIESHSRLEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW00</accession>
    <name>U1MW00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00443</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88300">
        <property type="protein sequence ID" value="ERG88300"/>
        <property type="gene ID" value="J07HX5_00443"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048986_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007254">
        <property type="entry name" value="DUF373"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38815">
        <property type="entry name" value="PTHR38815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04123">
        <property type="entry name" value="DUF373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="39593" checksum="F6644F619C5AFE8B" modified="2013-11-13" version="1">MNTLVVCLYRGDPLPGSEPPVIGRSAVERLVTAAGVGDPEDSRVNCLLEGIRVARDLEDATVAVLAGTEGTVSSDRAIAEQIDRLSDTHDPTSAVVVVDSAEDERLVPIVESRVPVDAVDRVVVRQARDIESTYYQLKQFLADEQLRKSVLVPIGIALLAFPALLTLFDSITVSVSAIATVTGVFLLYKGLSVDRLLATLATEIRQGLYSGQVSLVTYVVAGGLSLVGLAAGGFAASSLQGDPAQLLVAVQFVHDAIPWLTGAALIASTGRLLDEFIRDDDLASAYLNLPFAAIAVGVAVRGFVSYLLTLSDERAPLTVPRVVYGPVEIDSFAVSGGTHLAVFILASIVISLIGVQVASYMSSAEYDVGPDERRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW09</accession>
    <name>U1MW09_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfite exporter TauE/SafE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00311</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88168">
        <property type="protein sequence ID" value="ERG88168"/>
        <property type="gene ID" value="J07HX5_00311"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1253532_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="22711" checksum="15DCD9421F0D12B8" modified="2013-11-13" version="1">MPVLLLSEAVTGLVGGLFHNEFNNVAFGFADEQRTPTEATAVLGIIATAGVAAVAVSVGLSYYALKLPAVVVKLYVASIIAVIAAVTLLKTVLDPTTEYRRRRLIGFAVLAGFNKGVAGSGYGPVVTIGSILSGVYEKSATAITTMAEGVVSLAGVGAFFLISTAGYELNLLLLPSVFTGGFFAAILAPYTVRVLPNRALSYLVPVYALGLAGVLLLQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW15</accession>
    <name>U1MW15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00459</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88315">
        <property type="protein sequence ID" value="ERG88315"/>
        <property type="gene ID" value="J07HX5_00459"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9661" checksum="D45243459F748DD7" modified="2013-11-13" version="1">MKRSCPYRLSAAHTPPCRVFLAEQPHSPIVLHPHPTMSSVLARSELAQHTLREHNPFQIPNNFLNNAQVDSKLVFVILPTTPPFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW36</accession>
    <name>U1MW36_9EURY</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="9" type="ORF">J07HX5_00479</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="gene ID" value="J07HX5_00479"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0046872">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
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    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
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        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="246" mass="26773" checksum="8C0DBC5E7BC3DA7C" modified="2013-11-13" version="1" fragment="single">MSQDFYDILGVSQNADEDDIEDAYREAVRQYHPDVSDDPNAEEKFKKAKKAKEVLTDDEKRQMYDQLGHERFIEAEKRGATDADRGGAGAGRAGGGTGGGPFGGRGGFEDVQDIFDQFFGGGQDRSQSGRDLKTRLEIDLEDAYAGVETELTVSRPEECSNCGGTGHPPEANARRCPECNGRGQTTQVQQTAFGRVQQQTTCRRCEGEGTLYDESCGSCRGDGVVRQDATIEVEIPAGIKDGQTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW53</accession>
    <name>U1MW53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00356</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88213">
        <property type="protein sequence ID" value="ERG88213"/>
        <property type="gene ID" value="J07HX5_00356"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_779887_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="355" mass="39192" checksum="E7393942FFE53021" modified="2013-11-13" version="1">MSQPVVDHRRHRRRARHSGVTRFSRSRIYAVTTKRARXXXXXXXLEAHDWGTPAERDDRVFELLDRVGLLKEHFYRYPNQFSGGQLQRIGIARALALEPDFLVLDEPVSALDVSVQARVINLLTELQERLEITMLFIAHDLSVVRHVTDRVAVMYLGNILEIGPTETVFESPANPYTLSLLSAIPGSSSPAPTGLDRVALRGSPPNPRYPPDGCPFATRCPAKVRPDAAADLSDDAWEAIEAFRRLLRERARQDEPVTRTILRRVGLVSNKQSVESIRSDLFAGVELPSAVADTIATATDRAYSSPAAAADLLAEEFGSVCDQTDGEVYTVGDGSRQSQCVRHGPAYDAPADAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW91</accession>
    <name>U1MW91_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00396</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88253">
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        <property type="gene ID" value="J07HX5_00396"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_554962_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="492" mass="53774" checksum="2F64CE8ABFC2B804" modified="2013-11-13" version="1" fragment="single">AYTMVGEQGFTLLTAVGSVDQLDAGTTVETDENWRLAKTDDLVIASTDGQFAAVRVYDMSGLLSPTTDEIVTFLKTVISTARDTTNSLASSSGVVTKTLKLLGDSARVLLCFSDGLAPGRRTTDAPLAIGYSEDPYSQSSDDTDRITATCLVFTTEELTDAAIRGLVSADRRRIELTHTHRDEDDLIRAEAVLGPALSRDKAAAPGATLETTHTGDELAISHENGDPIPTDQLTLWVDGVRADTQPAEKFDSFSQGDRLAVEVETLAQLTLQWVDEEERVIYNYVDRLLGADAFESTYTVETKRATFTYTGDQPAAVERLQIDHRTGVSSREEAAETDTLTAGDTLTLDNVEIGDVATLFLDVPQNPAGVDTIFAEARADIPDVSIEQERNGEEYDAYVHVEYSPWNERKTTNPNRFTIRVDGEPADTQFTDEYDTLSSQDAVRLNRPALGKRVTVEWTPPTEDSQPGPIEVARNQIVPQGYLIATYNNETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW95</accession>
    <name>U1MW95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00519</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88375">
        <property type="protein sequence ID" value="ERG88375"/>
        <property type="gene ID" value="J07HX5_00519"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079332_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="13300" checksum="528DBC6B6379AD9F" modified="2013-11-13" version="1">MSCRIDTHASTVSLGTSYQTTRDATVKYLGDXXXXXXXXVHMLPQERQQQKRSLNAIFVCMLVDTTVRCNRSDARTVSCCGRLCLERDLLLVHSAVRPMYHTHQVGSRPIEQQIMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWA1</accession>
    <name>U1MWA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00406</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88263">
        <property type="protein sequence ID" value="ERG88263"/>
        <property type="gene ID" value="J07HX5_00406"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="2"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="20033" checksum="386967625F9A6A0F" modified="2013-11-13" version="1">MHVAIAVFDGVDALDALGPYEVFGHARQHGTELTVGLCTHKRRETITTSHGLTVVPDGVLEPDEPPALLVVPGGGWTDGAETGVRAQTAGALPAAVAACHETGTVVASVCTGAMVLAAAGLTDGRPAATHHGAHTDLAEAGAVVQDARVVDDGDVVTAGGITAGIDLALHLLERTVGAGVAATVATTMEYERRGPVQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWM6</accession>
    <name>U1MWM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00507</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88363">
        <property type="protein sequence ID" value="ERG88363"/>
        <property type="gene ID" value="J07HX5_00507"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2461651_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="10137" checksum="19B80EC8A484F1BA" modified="2013-11-13" version="1">MTVCNIRIGNLNTGHPPVDYERGQAMWLSPRDCAHLHDRALQADYEHETVYGISDNDRKYYSLERAKTQLGYEPQDNAAEWNGKDKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWR5</accession>
    <name>U1MWR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00558</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88413">
        <property type="protein sequence ID" value="ERG88413"/>
        <property type="gene ID" value="J07HX5_00558"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085884_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="43"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="244" mass="27440" checksum="BCF790D1501EB0AA" modified="2013-11-13" version="1">MSIQEEFDAWAEAGKDRGMEQRHWHTAKHALARIPIEDGDRVLDLGTGSGYALRALRATQNAGPSVGLDGSPAMVQNARAYTDDDAVGYVGGEFHHLPFATASFDHVWTMEALYYADDPVQVIAEISRVLRPGGTFFCAVNFFAESKQTHAWRDNVDVAMTLWGREAYREAVRAGGLRVAAQDTIPDEEVTIPPAETFPIEDWETRAAMFDRYRRWGTLLTVGVXXXXXXXSSRTPRRFRWRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWS4</accession>
    <name>U1MWS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00568</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88423">
        <property type="protein sequence ID" value="ERG88423"/>
        <property type="gene ID" value="J07HX5_00568"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1464113_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="184" mass="18914" checksum="68704ACF283DCB2A" modified="2013-11-13" version="1" fragment="single">VGVPTTALAGGLLLFGGPVVLVATGLVLQYRYGELAGAAVDAVVERVPVLGPIYHSLEQSRQVLTEEGFSEVVSLELADGVDVLAFVVGRGSGADWTAGDRRVTVFVPLAPNPTVGGHLLAVRSERVSTTGLGVRGALTVLATVGASRPDASDTETASETDPPVAGLYRELAADELPEQSIPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWS7</accession>
    <name>U1MWS7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00751</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88605">
        <property type="protein sequence ID" value="ERG88605"/>
        <property type="gene ID" value="J07HX5_00751"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13128" checksum="3944D5810892CE50" modified="2013-11-13" version="1" fragment="single">MSDPLLVVDDLRTHLSVDGGVEAVEEVSFTIEPGETTCLVGESGSGKSLACDSIIQLVRPPAEHTGTVRFEDRDLLSASDETLQSIRGDRIAYVFQNAQNALDPVYTIGSQIDEAIRFTATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX88</accession>
    <name>U1MX88_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00749</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88603">
        <property type="protein sequence ID" value="ERG88603"/>
        <property type="gene ID" value="J07HX5_00749"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1987532_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="14230" checksum="11CCB1BC989D7023" modified="2013-11-13" version="1">MSSSPDDSFSDDDFTPQTDGAPSSAVIEQTALTEQRRWWWRSPELLTLIVGVIALMTVFFRHRSSDETYLIRRWSLSGADWLLLLALVVLIAVVVVPLLRRPRRSKRLLVELLRRPRTALAVGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXT4</accession>
    <name>U1MXT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell division GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01098</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88950">
        <property type="protein sequence ID" value="ERG88950"/>
        <property type="gene ID" value="J07HX5_01098"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_802930_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="345" mass="37371" checksum="209D2AA096C089E6" modified="2013-11-13" version="1" fragment="single">LGGGTGSGGTPVIARHINSVYDSLPVYVVGVLPSKREGQLYAYNAARSLQTLLQGASPDNPSDPVDLDPGPDTNLSARAAEDSSEARLIGPDESITEAQETTSTPLAENIILVDNDAYSRPDESLEQAWEYINRTIAQAITDLFAAGEPLENKRIPESVVDTADIKQTLDGGRLSTIGYATSDLETDTTQTLLDRVRGTESTDLDSYDFDQQEAELRIMNLVREATQTALGFDTTLESVTTGLVLVAGPTDVLNRRGIQRSRDWIQGQVEAPAVRGGDYPRDQPEVQTALLLSGVHDSDRLRELYAQAAKARQTIEDIDDTEAVDTALTDPPTPPDYEHQIDGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY07</accession>
    <name>U1MY07_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01034</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88888">
        <property type="protein sequence ID" value="ERG88888"/>
        <property type="gene ID" value="J07HX5_01034"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_16_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="183"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="312"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="420" mass="47630" checksum="DCBC8DF1C8DAC891" modified="2013-11-13" version="1">MPNQAVTRTLTASLTNHSQVSDDLDSHGFAASKLWNIGRWTISRVWDAIGHIPDADELCSYLKKHDRYADLHSQSSQRVLQELGEAFVSWYKQDDPDANPPGYRKHGDEHPRSTVTWKNQGFKLDTTYNRVRLSKGTNMKPSRYAADYILCEYTIQADEQTLADVETVKTVRAVWTGDQWELHFVCEMQIDQPETPGEKTAGIDLGICNTAAVSVGDETLLYPGNVLKEDTHYFRQEEYNTEGKNGPSNHAEWARQKKSRRQNHFLHALSKDIVEQCERRNIGTIAVGHPKKIREDEDWGRHGNKRLHDWAFETLLSHIEYKAEERGISVERVLEGKLKTSKTCCECGKEADSNRVERGLYVCENCELVANSDLNAAENMRSTVTPSPEVDRSNGCLAQPSVRLFDKSTGRVAPQEQVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY14</accession>
    <name>U1MY14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01206</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89055">
        <property type="protein sequence ID" value="ERG89055"/>
        <property type="gene ID" value="J07HX5_01206"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490322_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="10072" checksum="C2E37322E00908A0" modified="2013-11-13" version="1">MLCKEETPADEQVALTSDEYLCRSCHGDLRTFKRTRPLHLWVTPTAWSSTKQMLRDQYDTQRSLLGELSVEYDEIAPLPSRQFHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY20</accession>
    <name>U1MY20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferases involved in cell wall biogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01049</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88903">
        <property type="protein sequence ID" value="ERG88903"/>
        <property type="gene ID" value="J07HX5_01049"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="40"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="354" mass="38615" checksum="B188CFE007243AF3" modified="2013-11-13" version="1">MQRRRGEKSATGAGAASAAAADVERSGTTASLEESAVKTSFVLPAYNEAGNLRSLVEEIVSVTDGESMAAYRPVEAILVDDGSTDGTADLVRELATEYEPVQGVLLRRNFGQSAALCAGLDEAIGKFVVTMDADGQNNPIDAPTLLDRLTDGYDCVSGWRANRADSLSKTLPSKIQTYLATYTGPNIHDFGCTLKAYRREAVDELQLRGEGHRYIPAKLYNRGFSITEERVDHRPRTHGSTNYGAVRLVRGFVDLGFNIFWNKYSMRPLHLLGGLGTLLLTFGGVLGSYSLVEKYVFGASLAPHLPRLILTVALVLFGFQLVMFGVLAEMLTRVIYRDETPYRIGSRVDGTTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYD1</accession>
    <name>U1MYD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01178</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89028">
        <property type="protein sequence ID" value="ERG89028"/>
        <property type="gene ID" value="J07HX5_01178"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2662243_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8932" checksum="1630E2C40ED85D1F" modified="2013-11-13" version="1">MRARHGEFEQIRSVLTEANTEGPLTAREILTILKQHGEEFNSAHRVATVLGRRAQTGEVDVIRDHPYRYRLQFTENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYK7</accession>
    <name>U1MYK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Double-stranded beta-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01411</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89255">
        <property type="protein sequence ID" value="ERG89255"/>
        <property type="gene ID" value="J07HX5_01411"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149791_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="11832" checksum="A7393562AE7D8085" modified="2013-11-13" version="1">MNTDSVRDVADGLVESGAESTESLRTDNVSLEVMRFEPGDEDQMHAHGEDEIYIVQSGNAEINVENEVTAVSAGDIIHLEPGTDHRFQGFEDELIMTVAYAPAKGTHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYK9</accession>
    <name>U1MYK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01265</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89113">
        <property type="protein sequence ID" value="ERG89113"/>
        <property type="gene ID" value="J07HX5_01265"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2190942_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11006" checksum="9B53FC819EDA1069" modified="2013-11-13" version="1">MLRTLVRIAGLPPVFTTTLASALNRVVLPLLSKGWASSQVSFAPVVALASTLVGVGLAAATGGRAALSPTNVEPASEQARPKLDASVRRLAATVGMETSQVALADAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYQ5</accession>
    <name>U1MYQ5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="6" type="ORF">J07HX5_01316</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89163">
        <property type="protein sequence ID" value="ERG89163"/>
        <property type="gene ID" value="J07HX5_01316"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033319_0_3_2"/>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="3 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="4">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="5">
        <location>
            <begin position="179"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="184"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="383" mass="40210" checksum="4F985B67BA26DB62" modified="2013-11-13" version="1">MLEDRNVVLCVTGSIAAVRTVELAHELRRQGAAVRAVTTPGATGIVHPWALEFATERPVVTEITGRVEHVELCGRDGWADVVLVAPATANTVGKIAAAIDDTPVTTTVTTALGADCPIVVAPAMHEPMYDHPGVLDALDRLEDWGVRFATPRLEEGKAKIATTSAIVTELARATTPAPLSGRHIVVTAGATTEPIDPIRTFSNRASGRTGRAVARACYTRGADITLVHDGPTKPWAAVERVETAAEMLAAVQAHADQADAVVSAAAIADYTTDPAAEKLRSGADQLVVELKPTPKLVERVAADHSIPVVGFKAETDADDSALVDQARRLQDRAGLLFVVGNDASVMGAADTRAVIVDDSATTWIEGSKQQLGTKIANRLSVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYY2</accession>
    <name>U1MYY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01523</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89365">
        <property type="protein sequence ID" value="ERG89365"/>
        <property type="gene ID" value="J07HX5_01523"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114810_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="14"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="21966" checksum="7E74A60466A80962" modified="2013-11-13" version="1">MSQTEQDPTSLLPTALIVDDEKEVADAYALRLRGVCDIETVYGGQAALSTVESRETDIVLLDRHMPSMSGDEVLETLTERGYYGRVIMVTAIDPNFDVLDMPFDDYLCKPIDREDLRAAVTQQLTVLGYETLGEYFRVESKRQVLEAEIAAVERADHDAYQEIKQRSAALKTRVDRVLEDAEASLDQFAAVGREGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYZ6</accession>
    <name>U1MYZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01538</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89380">
        <property type="protein sequence ID" value="ERG89380"/>
        <property type="gene ID" value="J07HX5_01538"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2340035_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="97" mass="11161" checksum="53818EEAAA74B319" modified="2013-11-13" version="1">MQTNIYHSHTNYRIADYPTPATAEELFNETKRRLPCLSVFTECPIEFDDIIFKHSIGALSNCIDFFSESWGLFVIELGCVSEPVVNTSRKSRIHTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ02</accession>
    <name>U1MZ02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01548</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89390">
        <property type="protein sequence ID" value="ERG89390"/>
        <property type="gene ID" value="J07HX5_01548"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065536_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019475">
        <property type="term" value="P:L-lysine catabolic process to acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008567">
        <property type="entry name" value="KCE_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37418">
        <property type="entry name" value="PTHR37418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05853">
        <property type="entry name" value="BKACE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="313" mass="33958" checksum="C6D69BB786D7D008" modified="2013-11-13" version="1">MRHLSSGNVIITCAVTGAIHTPSMSPALPVTPAEITEECIAASEAGAAVVHVHTRDPETGEPTTNLDVFEQIAARVTRETDVVIQPTTGGAPTMSPKERIQVVPRLNPEMCSCNMGSINFGLYPMVEMVDDWKYDWEPEYLAGTTDLVFQNTFEDLEVMLSTMADHSVRPSLECYDVGHLYNLKHCIERELIEPPLHLEFVLGINGGIGADAENLTHMKQTADRLFGDDYSFSTIGAGSAEFPLITQAVSMGGHARVGLEDNLYIRRGELAESNADLVAKTVDLAHEVAGREPATAEEVRTFLGLKGAEATAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ03</accession>
    <name>U1MZ03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hemolysin related proteins containing CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01430</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89273">
        <property type="protein sequence ID" value="ERG89273"/>
        <property type="gene ID" value="J07HX5_01430"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="224"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="297"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="452" mass="47940" checksum="2BDF4FD3B240D024" modified="2013-11-13" version="1">MVELIPATGRFVAALLLVGLNGFFVASEFAYVRIRSTAVDQLIAEGKTGASALGDVLDDLDDYLAATQLGITIASLALGWVGEPAVAALIEPVLGQVLPAGSIHAVAVVIGFSVVTFLHVVYGELAAKTVSIAAPERMALLVTPPMKLFYFLFKPALIFLNGTANKSTSLIGVPPASETDVSLSEEELRRSVAGAREGGKVDADEASMIDRVFELDDRTAREIMIPRPDVAAVSADMSPAALRQYVAERGHTRYPVVDADTGEQPLGFIDVKDLLQTPGANDSSDQDEEPTLTAGELANETPVVPESTAVDTLLEELREQERQMALVIDEWGTLEGIATVEDIVEVVVGDIRDEFDDNVAEPTIEDAPDDGYVADGSVALSTVNERLGLSLDSGAYSTLGGFVLDRLGRPPQPEDEVTTDNTRFTVTAVTDNRIDTVMIGGSVPADNPTGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ35</accession>
    <name>U1MZ35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01594</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89435">
        <property type="protein sequence ID" value="ERG89435"/>
        <property type="gene ID" value="J07HX5_01594"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="132"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="357" mass="39228" checksum="CAF110C3D2B29B23" modified="2013-11-13" version="1">MLTEXXXXXXXXSVPAVQTLGQDALLEDMSDPVVIVDNSQQIVTTNAAADAVFRSNGQQLLGSSVESAFDMDMSLNISEAFRTTVTDGPREFDLQVSPITDWQSRPLGALLVFREITKQRLREQRLSVLNRVLRHNLRNQLTVINNHAAILNEQFETGNGHIEQIHTAAERLTHVGEKAREVERSMDSSTEPVAADVVAIAESVVATHQSTTQQAAIQTDFPEQATVRCRHAGLIELTIDNLVENATEHTDVDEPRIAVSIEQTTASGGQVTVTVTDTSPGIPRHEIEFATSKTRAETPLKHSLSLGLWTINWCVRRLNGTISFETTASAGNRVVVTLPTDAVRKNSFSNDDSFRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ58</accession>
    <name>U1MZ58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosine deaminase related metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01629</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89470">
        <property type="protein sequence ID" value="ERG89470"/>
        <property type="gene ID" value="J07HX5_01629"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="53"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="434" mass="46541" checksum="29ACD2B3A741CF7B" modified="2013-11-13" version="1">MRLANIDTAFLQDDNRTVRHDLDILVQGGEIVAVAPDLSDQTGHHVIDCHDQIAVPGLVNCHAHTAMQFARGLSDDEPLFEWLATNGTYTAVVDRDTKRAACRLATRLMLERGVTTVHDMWNTYLADEFTDLGIRAVIGSTMAENEPSSPSKTRPRLEKTREAIAAFAGRPTLHPSVPVHSVYRATPELLQAAHDLAADADIPFHIHVAENATEVRRCRDVHGTTPVGVLDQMNVLDEHTVAVHCTELTNTDRERLGAAKAGVAHCPSANLKLGSGVANVSAVPDDVAVGIGTDGAGSNNDLAPLREARLATLLQKQEDPAAVDAQYALDMMTREGAAVLGLEDRLGSLLPGHRADITLFDSTDPALTPAIGDAGLLSNLVYSFHGHAETVLVEGRVVVDDGRCLTDTGDAAATVETFQAEMADSEGRTPYRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ71</accession>
    <name>U1MZ71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AICAR transformylase/IMP cyclohydrolase PurH (Only IMP cyclohydrolase domain in Aful)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01501</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89343">
        <property type="protein sequence ID" value="ERG89343"/>
        <property type="gene ID" value="J07HX5_01501"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="3">
        <location>
            <begin position="128"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="659" mass="70400" checksum="790F09C2711525B8" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZG3</accession>
    <name>U1MZG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01592</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89433">
        <property type="protein sequence ID" value="ERG89433"/>
        <property type="gene ID" value="J07HX5_01592"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095208_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="240" mass="25547" checksum="A8A684973E02B56E" modified="2013-11-13" version="1">MSYRPHQESDRRASLSGCVNAVALCRLPPTHQLDVSKLERPAVRWAIAFLFLVVELLLFVVIPEPGNEGRYQITPASQAVMIAVSLVLFAIIPSILKDLAVKDRPYVSAADQVEVTQQRRAAFIAGAVDRGAELIRIDTTATVASWIAAGFLLLLAGGTVTASVSGLPIRLICATTAYLLLAAFAAPPVRGYLSRKLRVAFPRSVVVTVLVVGVLLNEVALAPPTEAPAAVVTGLCLPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZJ1</accession>
    <name>U1MZJ1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arginase</fullName>
            <ecNumber evidence="3">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01795</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-arginine = L-ornithine + urea</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89625">
        <property type="protein sequence ID" value="ERG89625"/>
        <property type="gene ID" value="J07HX5_01795"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_2_2"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="301" mass="31636" checksum="6E0DEA931A002532" modified="2013-11-13" version="1">MDKTARIIGVPMDLGADRRGVDMGPSAVRYGGLAAGLEAVGWTCTDDGDLVVPRAEERTAAYDGDGAAKYLSAIKTTCEQLRDRVTAARREGTLPLVLGGDHSVAIGTVAGAADRQTGLLWLDAHGDYNTPTSTPSGNVHGMPLAAILGEGPFDDCSWAHTPTVDPANVALVGVRELDAVEQRRLRESEVSVYTMSDIDQRGITSVARAAVDVATDGVEQVHLSLDLDVVDPNEAPGVGTPVRGGLSYRESHAAMEVIDIEARDLVCSVELVEVNPILDQKNRTAELAAELTASALGDTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZP1</accession>
    <name>U1MZP1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S6e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps6e</name>
        <name evidence="6" type="ORF">J07HX5_01683</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89518">
        <property type="protein sequence ID" value="ERG89518"/>
        <property type="gene ID" value="J07HX5_01683"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109671_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00512">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_S6e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020924">
        <property type="entry name" value="Ribosomal_S6e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_S6e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="PTHR11502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13276" checksum="EED323796D0D56BE" modified="2013-11-13" version="1">MVELTVAVADPDDGVTRQVEVTEQDANRFIGKSLGDPVDGSAVGLSGYTLKLTGGSDDAGRPMRADVSGSNLRSVLLTGGTGYNPSRDGERRRVTVRGGEVSDATRQINAKITGRGDDPVEELLASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1N086</accession>
    <name>U1N086_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01905</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89733">
        <property type="protein sequence ID" value="ERG89733"/>
        <property type="gene ID" value="J07HX5_01905"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="26840" checksum="C5DE5C719739D69F" modified="2013-11-13" version="1">MTFDLSGEIALVTGGTRGIGRAISETLAASGATVVANYHSNEQAAAETDRHLSEHNDDSRVLQFDVSDADAVSDAFETVAATVGAPTILVNNAGILEQDTLDCTTEDCWDSVVDVNLKSTFLCAREALGPMRDAGRGAIVNISSVARENGAEGLGGYAATKGGQVSLTKVMAKEHGPYGVRTNAVAPGLIETDIWKETDGDGMLGGDEDEVRAMWAEQSPLGRVGFPEDVASVTGFLVSDQAAYLNGEVITVDGGTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0K3</accession>
    <name>U1N0K3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-dehydroquinate synthase</fullName>
            <shortName evidence="3">DHQ synthase</shortName>
            <ecNumber evidence="3">1.4.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-dehydroquinate synthase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aroB'</name>
        <name evidence="4" type="ORF">J07HX5_02158</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) = 3-dehydroquinate + H(+) + NADH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:25956"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58859"/>
            <dbReference type="EC" id="1.4.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal-type DHQ synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.24" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89985">
        <property type="protein sequence ID" value="ERG89985"/>
        <property type="gene ID" value="J07HX5_02158"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056379_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102042">
        <property type="term" value="F:dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01244">
        <property type="entry name" value="Arch_DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002812">
        <property type="entry name" value="DHQ_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563">
        <property type="entry name" value="PTHR33563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01959">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006655">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="387" mass="42132" checksum="66D5DED2D8BB5077" modified="2013-11-13" version="1">MERAVWLKADQAVGDWETRKRRITDGIEAGVDWVLVDREDVSRVRELGAVNVAAFGGDDVHVLEAESEAVDSDATVVGKNAEGDGTVSLPEDFSGSADLSVLRQDEQDVTGGYVEIRDQKYEAFAEAVAATATYTIVVGEDWQIIPLENLLARIGDETTLVAGVQTAAEAQTAFETLEIGADAVLLDTDDPDEIRATVKTRDAVDREQLDLEFAEVTAIEQTSAADRVCIDTASLLADTEGMLVGSMSRGLFFVHAETDDSPYVDPRPFRVNASAVHAYVRGPGGETRYLSELTSGDTVQVVDTDGETREAVVGRVKIEQRPMFRIQARVDGQTVETLVQNAETIKLHTRDGRCAVTELSQGDAILLYHEDTARHFGEAVEETVIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0Q1</accession>
    <name>U1N0Q1_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Thioredoxin reductase</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_02060</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
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    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89888.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89888">
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        <property type="gene ID" value="J07HX5_02060"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="33"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="39601" checksum="09BBF26271C00FCC" modified="2013-11-13" version="1">MSVWVLAPSCPTTYKSLPPVVFSMTGNTADHHRMIIAGSGIAGLSAAIYAGRANNDPLVFEGDEPGGQLTLTTNVANYPGFPEGISGPELIQRMKEQATKFGAEIAHDIIASVEKLDNGRVRVETNSGETHTSDAFITASGASARTLGVPGEDELMGHGVSTCATCDGAFFRGEDMLVVGGGDAAMEEATFLTKFADTVYIAHRRENFRAEQYWVDQVLEKVDAGEIELMRNTELLAVEGTPEDGVDYATLARNETGYPSEALDAPETEQFEMDVGAVFLAIGHTPNTNYLADTPVEMDEAGYVVTEDTDGGGQTRTGVEGIFAAGDVVDHHYQQASTAGGDGTKAAMDANEYLETVPERDPVTEAGAAAAGSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P379</accession>
    <name>U1P379_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00083</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87942.1"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="335"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="534" mass="56316" checksum="281C3DE535501959" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P383</accession>
    <name>U1P383_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00088</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="251" mass="27167" checksum="5D39AFB9FE71031B" modified="2013-11-13" version="1">MTTPVLETQALVKQFGSVTAVDQLSLSVPADQRHAIIGPNGSGKTTLFDLVTGAVRPDQGRIQFHGQDITTASEDARAREGIVRSFQLTNLFGGLSVQENLQLAVQATEQTFNPFRLPDTAIVERASEWYGALELDADPQAPVETISHGDRNRLEVGTALATDADLLLLDEPTSGVPPEESRALLRLIEQMTTGQTVLLIEHDMDVALSFADQVTVLDRGSVITQNTPEQIVNDTAVQNAYLRGYGDTTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3H9</accession>
    <name>U1P3H9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00198</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88057">
        <property type="protein sequence ID" value="ERG88057"/>
        <property type="gene ID" value="J07HX5_00198"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080977_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007362">
        <property type="entry name" value="DUF429"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04250">
        <property type="entry name" value="DUF429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="239" mass="25472" checksum="88137B3906F25ADC" modified="2013-11-13" version="1">MTVVGIDGCPGGWVAVGYNRGQFQAASVFESIDAIWTAYEEADTILVDIPIGLRATSADPRRCDTAARSALGRRGNSVFPAPIRPAAHAESYEQAKQIQERHTDGSLGRQTWAICDKIAELDSFLASTAAAQETVHEAHPEVCFWALAGGEPTSYSKTGQPAAAVWERVDILEQTAADVLDSIRDAGRDLGGEAGNDDLLDAFALSLTASELTGTLQTLPADPDHDPVGFPMKMIYAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3R2</accession>
    <name>U1P3R2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00290</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88147">
        <property type="protein sequence ID" value="ERG88147"/>
        <property type="gene ID" value="J07HX5_00290"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030367_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_B_exo1" evidence="8">
        <location>
            <begin position="90"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="7">
        <location>
            <begin position="475"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="687" mass="77688" checksum="BD4E0D870A2AC55D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P471</accession>
    <name>U1P471_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="3">6.5.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_00445</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68080"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RtcB family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88302">
        <property type="protein sequence ID" value="ERG88302"/>
        <property type="gene ID" value="J07HX5_00445"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="8">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="296"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="322"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="399" mass="43509" checksum="0B90F2C49E1C8E73" modified="2013-11-13" version="1" fragment="single">EHAAHNFLANEFVVSNCGVRMVRTNLRYDDISGREEALVDRLFEAIPTGLGGGGVTEVSGSDVETILERGVEWAVENGYGVQSDLAHCEDEGVRPEADAGLVSKEAKDRGANQVGSLGSGNHFLEVQRVTDIYRDDVAAEFGLSPDQIVVLIHCGSRGLGHQVCTDYLRAIEQSHQELLDQLPSKELAAAPAGSRLAREYYAAMAAAINFAWVNRQLITHQTRQVFQQVFDRPWEAMEMELLYDVAHNIAKRESHTVEGSDRELFVHRKGATRAFPAGRSELPPAYREVGQPVIIPGSMGAGSYILRGGDQSLAETFGSTAHGAGRLMSRTQAKNEYWGGDVADKLEQEHVYVKAESGATIAEEAPGVYKDIDEVVQVSDALDIGDRVARTYPVCNIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4B4</accession>
    <name>U1P4B4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00486</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88342">
        <property type="protein sequence ID" value="ERG88342"/>
        <property type="gene ID" value="J07HX5_00486"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016739_4_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="38"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="292" mass="32373" checksum="440F3E53C35B9125" modified="2013-11-13" version="1" fragment="single">MRRSRLFVPTSKEAESAAEVRSAVLALRSGLVDHLGSGLFSYSPTGKRVRDNIESIIHAKMKAVGAQEVDLPGLQYADIWRKSGRFGEFEGEMFTFENRDGKSMCLASTHEEPMAALVRERVRSKKNMPLVVYQVGEKYRDDHPRSGLLRAKQFRTKDTYSFTTSEEALTEVYQQMKAAYIDIFEQLGLSYAIVDAAPGAMGGFGSEEFQAPADAGSDRMSYCQNESCRFGTKHPGDNEQCPQCETSLVTKNAIELGHIFKLGTRYSDPLGLTYDTPTGEQQVIMGSYGIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4K4</accession>
    <name>U1P4K4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00582</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88437">
        <property type="protein sequence ID" value="ERG88437"/>
        <property type="gene ID" value="J07HX5_00582"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3130707_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5124" checksum="561C3678F53B02EA" modified="2013-11-13" version="1">MSWEITGIDAVAEGLVARGFELLAREDSPDELAEDGEGGIPLVLAELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5M6</accession>
    <name>U1P5M6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="2">AGPR</shortName>
            <ecNumber evidence="2">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="2">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argC</name>
        <name evidence="4" type="ORF">J07HX5_00978</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88832">
        <property type="protein sequence ID" value="ERG88832"/>
        <property type="gene ID" value="J07HX5_00978"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_1_2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="3">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="346" mass="36251" checksum="4E8833E921CDC225" modified="2013-11-13" version="1">MTTVTASVVGGSGYAGGELVRLLAAHPEFELIQATSRSETNRTVGHVHPNLRGLDLRFTHPNELQSVDLLFAATPHGVSMTEIDRYREAADTIVDLSADFRLTDECVYDQYYDGHDRPELLGEAVYALPELHRNELPGATLIAAGGCNATAAILALQPLAEANLVGEPTVVDLKVGSSEGGAGGGAAAAHPERSGVVRPYAPTGHRHEAELAAELDVEAALTVHAVDMTRGASATCHTFPNADTAATTRALWTAYRDCYEAEPFVELVAGGSGLYRYPEAKAVAGTNRAEVGFALDEHSDRIVAFAAIDNVVKGAAGQAVHAANIAVGVEETAGLDFRGLHPVGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P611</accession>
    <name>U1P611_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01132</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88982">
        <property type="protein sequence ID" value="ERG88982"/>
        <property type="gene ID" value="J07HX5_01132"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2202376_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11609" checksum="7E29867CED53B137" modified="2013-11-13" version="1" fragment="single">GRELLADESRLLLVPGWLDIDGAGALKEYADDAGRPRGDIWENAIWADSITVEDSDLYLFQAIHQESDAVPENIDAIRAVTDSASQGESIDRTNTALALDDPLIATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6F2</accession>
    <name>U1P6F2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA polymerase II large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">J07HX5_01300</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal DNA polymerase II family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89147">
        <property type="protein sequence ID" value="ERG89147"/>
        <property type="gene ID" value="J07HX5_01300"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_295534_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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</entry>
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                <person name="Narasingarao P."/>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89412.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="161" mass="18026" checksum="86EC2B851C3F6E52" modified="2013-11-13" version="1" fragment="single">LTSIYTEPQTSLRKSRRSGQDVTTTLTGENLLQPGDQRLGVNKTVLDEAFDSITEYWSPHLADAVNNQAVKLVKTSGEFVWHQHTDTDELFLVQSGSLRLEFRERENVTLGSGELVVVPQGIEHRPVAEPEAELLLIEPAETVNTGDTQSEQTQEELQRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P792</accession>
    <name>U1P792_9EURY</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">J07HX5_01575</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
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    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="13">
        <location>
            <begin position="32"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="264"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="318" mass="34987" checksum="FFC338796E4B80BC" modified="2013-11-13" version="1">MLGLDEYEYESRRELAHGLFTPNKGPDPLGTWVDLGIMLLIIINVAAVVLQTVDAVAAATGELFFYLELVSVAVFTIEYLARLWAAGEHKQIKSSLFAEPVEGPLSQRVAFASRPLMILDLLAIMPFYLTVIGVGGVDLRFLRALRLVRLFRLLKLVRYSKAISSLTNAVYRRREKLVITLLLNVLLLVVASSAMYYVEHPHQPDVFSSIPATFYWGVVTLTTVGYGDVTPVTAVGQGLAGLFAVLGIGLFALPASILADGFEAQAEDSSDRTHTSTNADEPRENAEQHTQTTEQWQYCPHCGKQLADNSTDASPHDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7H7</accession>
    <name>U1P7H7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01677</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89512">
        <property type="protein sequence ID" value="ERG89512"/>
        <property type="gene ID" value="J07HX5_01677"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4162" evidence="5">
        <location>
            <begin position="135"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="225" mass="23810" checksum="50654427DF97BC1F" modified="2013-11-13" version="1">MGVLPEGYDVYDRLTGRQHIEFAIESKDTADDPMALLDRVGLAGDADRQAGGYSKGMAQRLVLAMALAGDPDLLVLDEPTSGLDPNGARRMREIIQAENERGATVFFSSHILEQVEAVCDRVGILTDGSLVAVDTIDGLRESAGGGTVLQITVAEPAEALRGAVAGVDGVDTVRLEDDELVVTCTDTSKMDVLFALDEAGADVVDFTTDEASLEELFAEYTNGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7I9</accession>
    <name>U1P7I9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00249</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88106">
        <property type="protein sequence ID" value="ERG88106"/>
        <property type="gene ID" value="J07HX5_00249"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1025273_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="271" mass="28524" checksum="A93AC6E3CFF218FD" modified="2013-11-13" version="1">MAADADRSRFRRAAGVNAVGNALKIVAEGSVGLATGSVALIADAAHSVADLVASLVVFIWGEGRFDGPDSDHPHGHARFEPLTALFVGGVIIVLGGNLLFESAQVVLDGSSLAFTPVLVGATLFAVVDMYIVYAYTKLANRTLDSTALRALALDCLNDLYTSVAVLIGVLGVAFGVSALDGLAGSAVSLLVISQGLTIVRENVEYLSGAAAPEHRRQEVRETLLTQPRXXXXXXXRAPRRLGRRRSRRPAPGRPTARSSTRGNRKTPPGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7J4</accession>
    <name>U1P7J4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-peptide hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acylaminoacyl-peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00254</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88111">
        <property type="protein sequence ID" value="ERG88111"/>
        <property type="gene ID" value="J07HX5_00254"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0007">Acetylation</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="6">
        <location>
            <begin position="393"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="601" mass="65543" checksum="5E3F32E4D6AAC249" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P839</accession>
    <name>U1P839_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00450</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88306.1"/>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00450"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1656821_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="159" mass="17301" checksum="154A4E9E59544CFF" modified="2013-11-13" version="1">MVDCWRCQTAVTPILNRVRRPCVGFATGTPAGVSRVGGLSCSLSAVGTGTRFSHVCSPTALSDTASLRGWTGHLRRTVRNPLRSDRFLSYDRSAYQLNVTTGNSRQACEQWTVSTTDGAYPRPEGRGIAPVRRITRPWGLCAARRCRPAKLPPAGGQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P889</accession>
    <name>U1P889_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative DNA modification methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01944</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UPF0020" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="35039" checksum="609122CEFFACB5FA" modified="2013-11-13" version="1">MRAPPPVPDVYVLELAGTDDAFAAGEARRVLDDVRVFAPGLAVASTVAGLERLAFTHRASERLTQADATVRQACAALAAATIDRRPTTAAVRAVDVRATADIDTQHAERALGDVLVECGFTIELEEPAHELRALFAGDQAVLGWRVGTTPRGYEQRQPTDRPFFQPGSMDPMLARAVTNMAGVAPGDRFIDPMCGTGGILLEAARVGARPVGLDVQPKMVQGTRENLARVVDDPTVLRGDAGRLPLVTDAVTSVAFDTPYGRQSHIAGDLTQLVADTLSEARRVADRGVVVGDQSWRAPATAAGWTVTDTFERRVHQSLTRYVLVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8F8</accession>
    <name>U1P8F8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bacteriophytochrome (Light-regulated signal transduction histidine kinase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00546</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00546"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="564" mass="61036" checksum="B3510F0D31B672BF" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8I1</accession>
    <name>U1P8I1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00576</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88431">
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        <property type="gene ID" value="J07HX5_00576"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3225879_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="44" mass="4521" checksum="7304FF75AB2B438D" modified="2013-11-13" version="1" fragment="single">MCGRLKRSFVAGLAFFLPLGLLAVLGYGLVVLLLEAVSTVAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8L7</accession>
    <name>U1P8L7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02044</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89872">
        <property type="protein sequence ID" value="ERG89872"/>
        <property type="gene ID" value="J07HX5_02044"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059741_0_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035402">
        <property type="entry name" value="DUF1611-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035086">
        <property type="entry name" value="DUF1611_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011669">
        <property type="entry name" value="UCP026760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40690">
        <property type="entry name" value="PTHR40690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07755">
        <property type="entry name" value="DUF1611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17396">
        <property type="entry name" value="DUF1611_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026760">
        <property type="entry name" value="UCP026760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1611_N" evidence="2">
        <location>
            <begin position="36"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1611" evidence="1">
        <location>
            <begin position="133"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="335" mass="34948" checksum="C19D715DDB91D42E" modified="2013-11-13" version="1">MRVVLLAHEQFPGRAKTAVGLLRYAEHEVVAVLDRATAGDRVLDHVTDVQDAPIVATMAEAPACDALVIGIAPIGGGLVDGWRPDIRAAIERGCDVIAGLHSYLAEDDTLRRLAATTDTALRDVRRPPDELSVAAGTAGAVDARVVLTVGTDCSTGKMTTSFELRDAARERGIDAAVVPTGQTGIMIADRGTAIDRVASDFAAGAVEQLVEAAADHDLLIVEGQGALAHPAYSGVTTALLHGAQPDAMVLCHLPNHETVRRYESFAIPDPPQYAELYERLAAPVSGAAVTAGALNTQALAPKMATAAVEEYAAELEAPATDPVRFDAGDILEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8P1</accession>
    <name>U1P8P1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Double-stranded beta-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02070</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89897">
        <property type="protein sequence ID" value="ERG89897"/>
        <property type="gene ID" value="J07HX5_02070"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1968790_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="15205" checksum="F11F69122DEB2240" modified="2013-11-13" version="1">MQELTVQSVAPAHEDARGTVYNLIDDTEVRNVLYVESDSGTNWGNHYHKSRTQYPYILQGGFTLYYQDLRHERSTPIKTAQMNVGDVIKIPPRVAHAFELDHPTEFIEIVNEPLGENGDRYDQDTVEIDGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAB8</accession>
    <name>U1PAB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase, TIGR04182 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01197</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89046">
        <property type="protein sequence ID" value="ERG89046"/>
        <property type="gene ID" value="J07HX5_01197"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026456">
        <property type="entry name" value="GCTrfase_AglJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04182">
        <property type="entry name" value="glyco_TIGR04182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="378" mass="40959" checksum="70F36890053A9D58" modified="2013-11-13" version="1">MAAYDDVCVLVPTYNEAATVADVIEQVRAEGFETVLVTDGGSTDGTRELAREAGAQVTRQSGSGKGQAVREAVEAIDQPYVLMLDGDATYRPEQAHRLVEPLLEGQAEHVIGNRFADLRPSAMTRLNMTGNRIINRAFGVIHGRNLQDILSGYRAFTRESFKRLSLGADGFGIETELAVECIRRDVQTAVVPITYDPRPEGSETNLRPVRDGANIIARLYQMARATNPLFYFGSVGAVSGLIGAVLTLYVAFDWLLNGIAHNVLALAAGVSILFAVQLVMFGVLSDLIVTTTREQNRRLERIANAVESEQGSYSVPHTRARSAAETTRISDTDAAGTDASTGDNLASQSSQLSDHEDNVKNTPENEQEEIAADVEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAY6</accession>
    <name>U1PAY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01412</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89256">
        <property type="protein sequence ID" value="ERG89256"/>
        <property type="gene ID" value="J07HX5_01412"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1021589_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="65"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="29654" checksum="4E882364DE15C8DA" modified="2013-11-13" version="1">MNYHVQMSSARSRIPPGRRSSQVPSLTVVLLCLILAVFATELSLHDGGSVSKFWFVTQPQLTPGLILGVFAHQSLSQLGINVVGVALFGTLAERRLGRRKFAQFVLMSAFIPAYLQVSYTWFGSDGPGYIGFGGATLGLMALSLLVRGHEVATRATILTDQQWLRLLFTVETVXXXXXXXRRDVLRSTSMVAGGLMTATTASGNGDVDPDNCIVCNGDENDKKYKIDEDGYEDVTVLSNKPDNESHFPLMMLLSQGVAGGRGTAKRMLSRWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB31</accession>
    <name>U1PB31_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl13</name>
        <name evidence="4" type="ORF">J07HX5_01449</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89291">
        <property type="protein sequence ID" value="ERG89291"/>
        <property type="gene ID" value="J07HX5_01449"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076922_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_L13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="PTHR11545:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="16784" checksum="1413F8BE9B3F466F" modified="2013-11-13" version="1">MSTTTFEPDTVIDARDCIVGRVASNVAQRALDGDRIAVVNTERAVITGREEQIKQKYRERREHGSDRGPYYPKRPDRIFKRSVRGMLPYKRPRGRDALENVRGYIGNPYETDYETELLTDTSLDRLSTIKFVSLGEISDSLGANVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBF6</accession>
    <name>U1PBF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01559</name>
    </gene>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10038" checksum="984EF961F53EAD7B" modified="2013-11-13" version="1">MQAGALKAYLDHFLPREIIGPVIIVFSLEGVIEGIFTLYVPEELATLGWGAVFVAAVVIVAYWGTADDQAAEALRDRLDEIDEQQASNEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBS2</accession>
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    </protein>
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    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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    </organism>
    <reference evidence="2" key="1">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <begin position="27"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="31662" checksum="79D837913A1BD5D5" modified="2013-11-13" version="1">MELYEATAAGTTDLYYVDMELYDTPEYGAAYILDADRPAVIETGLGASYDRVLAGLDQLGIAPEALEAIVVTHVHLDHAGGAGFLADACPNATVHVPTPGAQFLIDPAPLWAGTQAVIGDRLHYYVEPRPVPADRVAELGAGDRVDLGDHTLVAHPAPGHAFHQAVLYDLATDGVFPGDAAGIVTPALDGPQHATPPSDFDLDQATTDVAMLEELDPAALYYTHFGDTEPDGLLEAYVSVLESWVSAIEQARATHPDDAAVKAAFADQADTVEAWGEHHARAEERLNVAGVCEYLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBU2</accession>
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    </gene>
    <organism evidence="1">
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        <lineage>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="29" mass="3149" checksum="3146C9BC7549B5A2" modified="2013-11-13" version="1" fragment="single">MPAGSCIIYYLSATVHDDKPARLILLDAT</sequence>
</entry>
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    <accession>U1PC17</accession>
    <name>U1PC17_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Nucleoside 2-deoxyribosyltransferase</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_01801</name>
    </gene>
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            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89631.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007710">
        <property type="entry name" value="Nucleoside_deoxyribTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05014">
        <property type="entry name" value="Nuc_deoxyrib_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="101" mass="10586" checksum="BEAA2F2F0C81F3A3" modified="2013-11-13" version="1">MLTDHVGAVAPEEDLPDRAIHDRDVEWLNAADAVVAEVTVPSLGVGYEVGRAVAAGTPTLALYRPTGDHELSAMVRGCDAIELVEYNAIKTAAAAIAAFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCD1</accession>
    <name>U1PCD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89751"/>
        <property type="gene ID" value="J07HX5_01923"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058976_0_0_2"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
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        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
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            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
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            <end position="309"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="312" mass="33022" checksum="15970B1E925E93A2" modified="2013-11-13" version="1">MAERKDRNKPIDFICTNNVADVTDRLAGLAPSEQTLPGYLFWLSRPRFWLYLAGPVAVGVVYASTAAGQFFQPITVALFLYFLIPANVYLYGVNDIFDADIDELNPKKADDGREVRYTGGTGVQAAVLAAALLGGGFISVLPTAGVAGLAAFLLLGGAYSAPPLRLKTTPLLDSVSNGLYVMPGVVGYAAVAGTFPPIVAVAGGWVWAMGMHTFSAIPDIEPDRAAGIRTTATLLGTHRTLAYCAGVWLVAAVLMSVVHPYLGVVLGVYPVFVATIAAATVDIDRAYWWFPVLNTVAGTAFTLGGIWVIQYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCX3</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89941">
        <property type="protein sequence ID" value="ERG89941"/>
        <property type="gene ID" value="J07HX5_02114"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712703_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="7994" checksum="92D2C258DADEBA84" modified="2013-11-13" version="1">MGLLNTIGEVFNASTQSTNRGDVTQNNSEGAFWCHDCQERIRDVDVKGEGTPDCPSCGDVMEFERSKGTSSCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFJ3</accession>
    <name>U1MFJ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00020</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87879">
        <property type="protein sequence ID" value="ERG87879"/>
        <property type="gene ID" value="J07HX5_00020"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1976443_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="126" mass="13961" checksum="44CD9E4CCB286ACF" modified="2013-11-13" version="1">MILCLSGIADGIPQDDGGRAAEDIVHATHEFVYVPPLRPNSNFVFDKQPDYARDVGQERIRKMINAYRREIDAPTATFAEFISLAEHGSLRGDAAVERGALQERLDARPAPEWFIDEPDAHAFAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG24</accession>
    <name>U1MG24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00282</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88139">
        <property type="protein sequence ID" value="ERG88139"/>
        <property type="gene ID" value="J07HX5_00282"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="8682" checksum="0BC00E2093D6CF4B" modified="2013-11-13" version="1">MIPLVPTITNEAFLLIGGSVIVEVVFGINGIGWLFFQAALNGDLPLVAGLVFLFLVVVVVVNLIQDLLYVLIDPRVGYGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGM8</accession>
    <name>U1MGM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00503</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88359">
        <property type="protein sequence ID" value="ERG88359"/>
        <property type="gene ID" value="J07HX5_00503"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1567108_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="167" mass="18726" checksum="CC602DC5447788A5" modified="2013-11-13" version="1">MSTQVPKFELSNVGPGPDPFSLQALTDSVEFVILFFQRDHYCTNCRQQVQTIADRYDAFADRNAEPVSVVPEPPERVAQWQQKYNLPYPLLADPDATVGEAYDQPVRFGILGQISDFFGRMPAVILIDHRGDEPTIEYTYEGSSTLDRPDPGELLSELDALRETAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGZ8</accession>
    <name>U1MGZ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mn-dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00680</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88534">
        <property type="protein sequence ID" value="ERG88534"/>
        <property type="gene ID" value="J07HX5_00680"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="231" mass="25147" checksum="E4E7D7E8776B0F98" modified="2013-11-13" version="1">MLSAKMEDYLRAVYELQRRDGGSVATSSVAEALDVTPPTATSMLGTLADRGLLDREKYRGVELTPEGETVALEIIRHHRLIETYLAERLGYDWTEVHDEADSLEHHISEAFERRVADQLDDPDVDPHGDPIPADTLDPVSGVEGTTLAARDEGEAVVVRRVQDDDPNELAYLEASGITPGTQILVEEVAPIGVMTVVPADDEPVAIPDGIAEVIWVDAVETQSWTEPNGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH05</accession>
    <name>U1MH05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Small GTP-binding protein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00690</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88544">
        <property type="protein sequence ID" value="ERG88544"/>
        <property type="gene ID" value="J07HX5_00690"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1399745_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="26"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="215" mass="23801" checksum="54F3C0E959275F2F" modified="2013-11-13" version="1">MGLLTSLRSSISNAVSAMTATEESKRIGIYGPPNAGKTTLANRIVRDWTEHGDAVGPESHIPHETRRARRKEDVEISRNEHTVTIDIVDTPGVATKVDYTEFLDHDMEEGDAVRRSREATEGVAEAMHWLREDVDGVIYVLDATEDPFTQVNTMLVGIIESQDLPALILANKIDLEDANADRIRNAFPQHETVPSSALEGNNIDEVYDNIATYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI41</accession>
    <name>U1MI41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gas vesicle synthesis protein GvpL/GvpF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01174</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May play a structural or regulatory role in gas vesicle synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
            <location evidence="2">Gas vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89024">
        <property type="protein sequence ID" value="ERG89024"/>
        <property type="gene ID" value="J07HX5_01174"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065736_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009430">
        <property type="entry name" value="Gas-vesicle_GvpL/GvpF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36852">
        <property type="entry name" value="PTHR36852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06386">
        <property type="entry name" value="GvpL_GvpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="276" mass="30624" checksum="E7C83A6165D76584" modified="2013-11-13" version="1">MAESVSDPPTTVSDGRYLYCLVDVAETNHPTLDTTGIGEAPVSVLTTDGIGAVVHPTETLYDSADSDQVRRWLVSHQRVIDDAAAAFGTPVPFQFDVVIENGDKGVTDWLVDNAPTITEALDRYSGLREYRIHVTWDRTTAANKASEDDEKLAAIEQRRAESSDGEQFLLDKQYDQRLETVLREQKTQFRDQLTATVEEAVDELIEHSPAPSVEDLSSRETADEWVARIAVLMSESSETTVGETLDEFATEPGVEIRFTGPWPPYSFSTEFFEGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI71</accession>
    <name>U1MI71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01216</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89064">
        <property type="protein sequence ID" value="ERG89064"/>
        <property type="gene ID" value="J07HX5_01216"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3110640_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5751" checksum="22897842E64F9C25" modified="2013-11-13" version="1" fragment="single">GRQQVEEELQEMEEEVSADVENEEFSNDEFESDSLGTDDEYTDLDSEKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI97</accession>
    <name>U1MI97_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01251</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89099">
        <property type="protein sequence ID" value="ERG89099"/>
        <property type="gene ID" value="J07HX5_01251"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_7_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="6">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="278" mass="30491" checksum="76AFDC8C5994802F" modified="2013-11-13" version="1">MDMVTFRENTEDVYAGIEFEAGTDAAAKVRTFIEDEMDVTDATHDGPVGLAFKPISEFATKRLVRKAIDYAIEHDRDTVTLVHKGNIMKYTEGAFRDWGYEVAREEYDDTVITEDTLWEERDGEQPDDAVVVNDRIADNMLQQLLTRTESYDVLATPNLNGDYLSDAAGGQIGGLGIAPGANFGDGLCLAEPVHGSAPKYTGQDKVNPTAMILSGTLLFDYMGWDDAATLVRTAVGEAIANRRVTYDLHRQLEDAEKLATSAFADVVTGHVEQLAQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIB1</accession>
    <name>U1MIB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01271</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89119">
        <property type="protein sequence ID" value="ERG89119"/>
        <property type="gene ID" value="J07HX5_01271"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="125"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="382" mass="41084" checksum="8077C6DC738AF395" modified="2013-11-13" version="1">MQLLSSAPVPEEARDVKAAANEFANEHVRPRSAEFDASEAFPHEIVHRAQAAGLAGSYVPEEHGGAGWTLAHRLAVIEEWFHADGGIGLALQLADFGAKVVTVAGSSEQQAEWLPAVANGDTITGLAATEPAGGSDLAGMATTARREGDEYIIDGEKYWTSNGVVADWIVVYAQTGDTGHQGYSLFIVPTDDPGYDAEPITGKMGLRASQQAQISLDGVRVPAANRLGEEGSGFYNLASFFNYGRIAVAGHGIGLAAAAIESAWEYVHDRELYDAPVADKQTVQHRLVEMREQFEAARALSWEACKHVMAGDNAPLWASLAKSQATRAAESIAQTAVQLHGGEGLREETRANRIYRDAKYPPIYEGANAVQRDLVYSHWPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MID3</accession>
    <name>U1MID3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01302</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89149">
        <property type="protein sequence ID" value="ERG89149"/>
        <property type="gene ID" value="J07HX5_01302"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1131574_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="245" mass="25669" checksum="646368BED2B2DA36" modified="2013-11-13" version="1">MSWIRSSETLVLGLVVVLALGAVGTATAIELNRTTVPDDLEVGEETEVEVTIEDPYADVSGEYELSATTEFENGQVSISATTPSGDSDTVSRGDSLTVAPADNYEEIIVRASGTVPDIGSNGGAYSYENPEQEQFTALDVSADGPIPPVSVGRFTENSREARELIDDAVNATGEDADGVQSAISLYNSGNFDQAITQAGNVIDEEGSSGLSPLLLIAGVVVVVIGLAGGGYYLYTQRKQDTHKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIL7</accession>
    <name>U1MIL7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="8">SHMT</shortName>
            <shortName evidence="8">Serine methylase</shortName>
            <ecNumber evidence="8">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyA</name>
        <name evidence="11" type="ORF">J07HX5_01416</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89259">
        <property type="protein sequence ID" value="ERG89259"/>
        <property type="gene ID" value="J07HX5_01416"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="10">
        <location>
            <begin position="6"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="352"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8 9">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="370" mass="39366" checksum="841CD3EDF5469CF3" modified="2013-11-13" version="1">MYEQVRETDPAAADALAAERGRQNETLTLIASENYASEAVLEAQGSELTNKYAEGYPGERYYAGCENADRIEELAIDRAKELWGADHVNIQPHSGTQANMAVYLSILDPGDRILSMALDHGGHLSHGHPANFTGQTYEVEQYQVDPETGYIDYEGLRATAESFDPDVIVSGYSAYPRDVEFAEIQRVADTVDAYHLADIAHVTGLVAAGVHSSPIGVADFVTGSTHKTIRAGRGGIIMTDDEHADAIDAAVFPGAQGGPLMHNIAGKAVGFGEALEPAFDEYADQVIANAQALADQLREHGLSLVSGGTDNHLVLVDLRDSHPNTTGKDAEAGLEAAGIVLNANTVPGETRSPFIRXXXXXXXTSGGRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJP3</accession>
    <name>U1MJP3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">P5CR_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01886</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89714">
        <property type="protein sequence ID" value="ERG89714"/>
        <property type="gene ID" value="J07HX5_01886"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2695600_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P5CR_dimer" evidence="1">
        <location>
            <begin position="18"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="8100" checksum="62C5480C44AA8752" modified="2013-11-13" version="1">MDTLFGKRQRXXXXXXXSEQSIDELIDSVCSPGGTTIEGMRELWESTAESDLITAVHAAEDRSREMAAEFADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJR4</accession>
    <name>U1MJR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01911</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89739">
        <property type="protein sequence ID" value="ERG89739"/>
        <property type="gene ID" value="J07HX5_01911"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072455_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="68"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="215" mass="23744" checksum="2F3BEFB360FF1132" modified="2013-11-13" version="1">MLDYLSEAERSKIDSRSDETFYETPRFVTHADDAFLETLTQTYATVLSNDDRVLDAMSSWVSHLPDKQYDRVVGHGLNAAELAANDRLEEWFVQDLNSSQSLPVDKNAFDAVLCALSVQYLQYPAATVREFARVLAPGGALVVSFTNKMFPQKAIRAWRGANMDGRRQLVTEYCEAAGLAVTDVIEAQPGTDPFVAVVAQHPDEDGPTAQSATHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK06</accession>
    <name>U1MK06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine/D-amino acid oxidases (Deaminating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02016</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89844">
        <property type="protein sequence ID" value="ERG89844"/>
        <property type="gene ID" value="J07HX5_02016"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="18"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="398" mass="42516" checksum="93983C0EB0651AA8" modified="2013-11-13" version="1">MTDTPATTPSEPVTRQRITIIGGGVIGLTTALVLARRARATGHEYNIQVLEREPRLGSQSTTAAGCGLRTVYRHPVNIDLARKGLQFWANAGALFNGDIGFRRNGYLFLTANSETAATLERETTRQVAIGAPAEYDTPPVVPDVAPALNAGEYTASLFSSNAALATPQKIVDTVATAAAEAGVELRTDTAVTNLTPHDKGVTVEADGESEHADVMINATGAWADKIAGLAGETLPITADRRRLAVLDTSISSDAPLMVDIDTGMFMLPREDGKVYAGGKFRSEAGQTDPDDPAAFTTEVDNEYIDRLKTHGRQLYEPLDDATVIESWSGLYAMTDSHVPIIDRSRNMIHATGFSGHGIMQAPGAAMLIARMLDPGQTATQPLATLSRDRTVTTPDIQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MUZ6</accession>
    <name>U1MUZ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00021</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87880">
        <property type="protein sequence ID" value="ERG87880"/>
        <property type="gene ID" value="J07HX5_00021"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165165_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="12419" checksum="4FE9839514F1CF30" modified="2013-11-13" version="1">MEIERRIEKLHELIRSERAINEINSELTVNLGPPLSDTAADMADLPRRLIYRLFDEGRLTTEEYGAINKERIRRSEEGEVDPRPPAGAIDPDETKQSGGSEAFLDIAVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVA2</accession>
    <name>U1MVA2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00014</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87873">
        <property type="protein sequence ID" value="ERG87873"/>
        <property type="gene ID" value="J07HX5_00014"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_693736_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="PTHR14025:SF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="30"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="397" mass="43968" checksum="F1D5CD58732974F3" modified="2013-11-13" version="1">MSDAFAGVEPASGALREPGVXXXXXXXLRLAEAALSDHSLVSLPTGLGKTAVSLLVTARRLHESGGRALLLAPTKPLVTQHAQFYREALTIPDDEVVVFTGEVRPDDRAEHWQDAQVVVATPQVVENDLIGNRISVAEVVHCTFDECHRATGAYAYTYIADRYHADADQPLATGLSASPGDDKEAILAVCQNLGVENVEVMTEDDADVATYTHETTVEWERVELPESVEEIRDRLRAVIRDRLGNLTDLGVTRKSSPDLSERDLRQIQQRVQELMDDDDSAGYEGMSLSPRSENSGQRSLCRNSERCGFQQYMTRQQEAARSSGASNADQRMVSDPKVQAAVRQGEACDGLHPKIPASEDDPRRDTWYRGRRARDCVHRVTGYRRGPDRVSRRALQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVB0</accession>
    <name>U1MVB0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ORF">J07HX5_00176</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88035">
        <property type="protein sequence ID" value="ERG88035"/>
        <property type="gene ID" value="J07HX5_00176"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="272"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="255"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="421"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="509" mass="55027" checksum="66EBE228201E7EA9" modified="2013-11-13" version="1">MSETYVGAIDQGTTGTRFMLFDESGQAMANAYEPHDQQYPASGQVEHDPLEIWANTKAVVRRGLDSAEAAPDRLAAIGIANQRETTIVWDRVTGSPIHNAIVWQDRRTTTRVDQLADAGKIEWIRAKTGLEADAYFSATKLEWLLANADPPTHSGARSASVRERAAAGDLLFGTIDSWLIYKLTGNHVTDVTNASRTMLFNIDELAWDDELLAEFDVPEAMLPTVRPSADTALYGHTDPDGFLGAAVPVAGALGDQQAALFGQTCFDPGDTKNTYGTGAFYLMNTGTKRIDSEHGLLTTVGFQQTGEPVQYALEGSIFAAGAAVEWLVDIDLIADAARTAEIARGVNSTEGVYVVPAFTGLGAPHWDGDARGTIVGLTRGTRREQIVRAALESIAYRTRDLAEAMAADAGVETASVRVDGGAVTNNVLCQLQADILQAEIIRPQIEETTALGAAYAAGLAVGYWDNVDALRTNWQAGRRFSPTIPRDRADRMYDRWGDAVDRSLDWAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVK6</accession>
    <name>U1MVK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00288</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88145">
        <property type="protein sequence ID" value="ERG88145"/>
        <property type="gene ID" value="J07HX5_00288"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_206910_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="6265" checksum="1CDF1A3CBE52E0E1" modified="2013-11-13" version="1">MSDRPDAAAEPDPEPDRSDTNAPGTGAYETDEGTVIYDIDEPLAWVQGDNAVELIEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVM7</accession>
    <name>U1MVM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88023">
        <property type="protein sequence ID" value="ERG88023"/>
        <property type="gene ID" value="J07HX5_00164"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1492934_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19132" checksum="D86BF9CF89D34DEE" modified="2013-11-13" version="1">MATLAHFMLVGLWDLDMSGETLSEETDDSDKEAGTERGGPLFSIYRRYVGEPQSPREVYPGFGLFFAGVALGLAALVLFLLSGTQPAESGSFFQFREAALVFMMLALPAVATSVAVLLPIGQLTTAASLGGSLVCIVATAWLVQVYPYXXXXXXXXGSRDRVGTGGTASGSPDPNRREDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVP7</accession>
    <name>U1MVP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00333</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88190">
        <property type="protein sequence ID" value="ERG88190"/>
        <property type="gene ID" value="J07HX5_00333"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097410_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="249" mass="26517" checksum="71C280E60A737D35" modified="2013-11-13" version="1">MNRGPQQFVTAQTPRRPAPERVDEPISCHSALXXXXXXXGTSGRARSIPYNTDSYDTAGLPADIMAYPAFGGSLGWAPSYGSCQAFVTAMRIIEGETATRDWLEGVVDAGIASYPDEFAVCQAVADGEIDAGFANHYYTQRVLEGTPDAPIATAFTEADAGAAFNVAGAAIVDTAADSTLAERFIRHLLSAEAQDYFARSTFEYPLVPAVEPVGELPAIDELAVPDIDLTQLSDLEPTIDLMRDAGITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVT9</accession>
    <name>U1MVT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L16/L10E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00230</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88088">
        <property type="protein sequence ID" value="ERG88088"/>
        <property type="gene ID" value="J07HX5_00230"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1521815_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_L10e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="PTHR11726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="4">
        <location>
            <begin position="47"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="176" mass="19771" checksum="37EC2E8C27EC25A7" modified="2013-11-13" version="1">MCHGSLVAWCPAIGSQPRRFKGFIDIVGLTTTKIMSEKPASMYRDITKPAYTRREYITGIPGSKIAQHRMGDEHVEFEDYPVQISLVVEETVQLRHGSLESARLSANRHLIKELGENNYTMILRKFPXXXXXXXTDILQRAHIIKHPAHVGCHLVAASPLLLLTRLPERVGSRSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVU1</accession>
    <name>U1MVU1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00378</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88235">
        <property type="protein sequence ID" value="ERG88235"/>
        <property type="gene ID" value="J07HX5_00378"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_383840_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="581"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="657"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="690"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="722" mass="78584" checksum="D90E7823526B77CC" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVV2</accession>
    <name>U1MVV2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar kinase, ribokinase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00388</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88245">
        <property type="protein sequence ID" value="ERG88245"/>
        <property type="gene ID" value="J07HX5_00388"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846230_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="9"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="328" mass="33441" checksum="F125A58290A28D48" modified="2013-11-13" version="1">MAIVNSPDHVLVVGDTTADLHPAAALSPGSELQWFPGGTATNVARGLALFDTPPALATRVGTDPFGRAVRTRLTSLGIDTTRCVTDPRPTPLTMPDPTDDRPGDTWTAWVRDTCYGVTLPDPVDAVETADLVHCSGTVLPPAVNQATVTETIAATQSQNVALSFDLNGRHNQWESAASYRDALTAPLAASSVVFASEHDLTVAGREPTLAGLKTLFPDPPSALVVLTQGADGATAARFTDGAITTQASHPGFSVDVAGTAGAGDAVTAAVLALLQAGVTALGQLLAVGTAAGAATTASAGPVRPADRNRMARLLAEWPTAWAGDGPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVX6</accession>
    <name>U1MVX6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome-activating nucleotidase</fullName>
            <shortName evidence="5">PAN</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Proteasomal ATPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Proteasome regulatory ATPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Proteasome regulatory particle</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pan</name>
        <name evidence="9" type="ORF">J07HX5_00276</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88133">
        <property type="protein sequence ID" value="ERG88133"/>
        <property type="gene ID" value="J07HX5_00276"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022623">
        <property type="term" value="C:proteasome-activating nucleotidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00553">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005937">
        <property type="entry name" value="26S_Psome_P45-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023501">
        <property type="entry name" value="Nucleotidase_PAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01242">
        <property type="entry name" value="26Sp45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="181"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="192"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="402" mass="44867" checksum="BCB57B2ADC4EEBE0" modified="2013-11-13" version="1">MADTVDDVEMPYDDGTSEQDKIESLEERLDILESQNEEMRDKLLDANAENNKYQQKLERLTHENKKLKQSPLFVATVQELNEDEAIIKQHGNNQEALTEITDEMSKQLEPDDRVAVNNSLSVVKLLDDETDVRARVMQVDASPEVGYGDIGGIDDQIAEVRETVEMPMKSPDMFADVGIDPPSGVLLHGPPGTGKTMLAKAVANQTDATFIKMAGSELVHKFIGEGAKLVRDLFELARQHQPAVIFIDEIDAIAARRTESKTSGDAEVQRTMMQLLSEMDGFDDRGEIRIIAATNRFDMLDQAILRPGRFDRLIEVPKPNPAGREQIFKIHTRSMSTDEALDFSALATIIEDASGADIKAICTEAGMFAIRDDRTVVQMSDFEQAYEKIQAEEETQTDRTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW38</accession>
    <name>U1MW38_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylaminoimidazolesuccinocarboxamide synthase</fullName>
            <ecNumber evidence="2">6.3.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00341</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88198">
        <property type="protein sequence ID" value="ERG88198"/>
        <property type="gene ID" value="J07HX5_00341"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_867400_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="7">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="320" mass="34975" checksum="0609B0528D9285E0" modified="2013-11-13" version="1" fragment="single">FTNAYSVFDWGPMPDKIPRKGPSLCTMGADTFERLADHGVPTHYQGVIVDGDPSSLAAARTPPTELAFDLARVPELPETNRRYDYDAYFDAASTNVLVPLEVVVRNAVPVGSSLRRRRSPRDCGLDQANWPDHPVALPEPLVEFSTKLEASDRYLDRQEAAAIAGPVALPELEELALAVNEVITARAEAVGLTHQDGKIECVLTDGTLRVGDVAGTLDENRFRYQDQQLSKELLREYHRQHQSTWVEAVTAAKTAARQDSRTDWREQCSRSPTPLPTPVVATVSKLYATATDAYTGRDWFGVGSLETAASAAEQLTAPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWG6</accession>
    <name>U1MWG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00610</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88465">
        <property type="protein sequence ID" value="ERG88465"/>
        <property type="gene ID" value="J07HX5_00610"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172273_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="8459" checksum="ADD5393247538875" modified="2013-11-13" version="1">MSDLSEEDRAILKYLRDSVSRGESYFRAKNIANQLGLSSKQVGARLPKLDEASEDVEIEKWGRARSTTWRVTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWI2</accession>
    <name>U1MWI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00482</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88338">
        <property type="protein sequence ID" value="ERG88338"/>
        <property type="gene ID" value="J07HX5_00482"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2695595_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="7997" checksum="9FE716763B7D1514" modified="2013-11-13" version="1">MLATSWAHGGFGPDSTVTLLDKNGTTQSATETRQALNGDTSKLNPSWKSTAGTITRWLRPRPRTRPVEHSMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWM2</accession>
    <name>U1MWM2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00502</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88358">
        <property type="protein sequence ID" value="ERG88358"/>
        <property type="gene ID" value="J07HX5_00502"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103229_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="28515" checksum="5B6984D8A0DDC002" modified="2013-11-13" version="1">MSIVVAPAMPQSPDDRYPDMATVIELCMSRRAAEAGFKQFLEPTVTAIREEFSVERMLRDTDLELGGRLLDLIRANADTIERQLVSAELKSYQQQSLDQFQVVLDYVESDAPVDAFASQLLAHDSYMPALDPTLDTAQQATVADAVLTRLERLGDGVAPVVRRPEAEFWPAVDAAFNRQEAVTLLAEVFPFTGPLRAHREWFAFTTEIDPGSVLGPLGSALPAVTVDYTDETVRSMVRAEEQVINELQTAARSRISAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWR1</accession>
    <name>U1MWR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase of the AAA+ class</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00553</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88408">
        <property type="protein sequence ID" value="ERG88408"/>
        <property type="gene ID" value="J07HX5_00553"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_8_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="179"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="36086" checksum="A986929609B397A3" modified="2013-11-13" version="1" fragment="single">MENRVVAQLLTLMDGLETRDEVIVIGATNRVDTIDPALRRGGRFDREIEVGVPGETGRREILAVHTREMPLAEDVGLDVLAGRTHGFVGADLATLAREAGMAALRRRDDTDDDLVIAHADFETALTGVEPSAMREYVAESPTTTFEDVGGLEETKARLREAVEWPLSYSPLFRAAATEPPSGVLLYGPPGTGKTLLAEAIAGESGVNFIQVAGPELLDRYVGETEAAIRELFERARQTAPAIVFLDEIDGIAGRRGEGNETTERVVSQLLTELDRAADHPKLAVVAATNRRESLDNALKRPGRLEQHIEVPYPDESARREILAVHTRETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWX1</accession>
    <name>U1MWX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucyl aminopeptidase (Aminopeptidase T)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00618</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88473">
        <property type="protein sequence ID" value="ERG88473"/>
        <property type="gene ID" value="J07HX5_00618"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102437_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00919">
        <property type="entry name" value="THERMOPTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="26029" checksum="B91081F4799E16CA" modified="2013-11-13" version="1">MSHTTPDPSKRTARRTLDSRLRGVCLRRSEQRLESGSRAPTTAGRVARPAEEVRILSGDSTDIRLSVAGNPSQNNAGEHNLPGGEVFTAPVIDSVEGQALFDKPVHRDGRAVTDARLQFEDGEVTDYAVTKNESLLGEIIATDAGVRRLCEIGIGMTRDIDRFSYNMLFDEKIGDTVHMALGRAYEDAVDPDNKHNQSAVHVDMVVDMSENSFIVVDDETIQRDGRFVFDRVDNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX26</accession>
    <name>U1MX26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alanyl-tRNA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00679</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88533">
        <property type="protein sequence ID" value="ERG88533"/>
        <property type="gene ID" value="J07HX5_00679"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="26296" checksum="5167D8056D546A5C" modified="2013-11-13" version="1">MTELLYLPADDNTTSFTGTVTDATTEYLVLEGTHFYPVGGGQPADRGTMNWDGGQAEIGGVRKSHGEVRHEIASLTGELPAPGETVEAAIDAARRDTLSRMHTAQHVVSRVALNEYGATTAGNQIYPDRSRIDFEPVSFDEDDVSLIERRSNAAIDRDPAVIKEQRARDQVEREVDEGRALLELIPDSVDPLRVVEIDGFDMCPCGGTHVNSLSEIGSIEITNHTSKGADTERIEFVLTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX79</accession>
    <name>U1MX79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00739</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88593">
        <property type="protein sequence ID" value="ERG88593"/>
        <property type="gene ID" value="J07HX5_00739"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_893129_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010545">
        <property type="entry name" value="SPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06550">
        <property type="entry name" value="SPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="311" mass="32111" checksum="6BAD206A6C1D9B24" modified="2013-11-13" version="1">MARSTRLTVQLIPPGYGVCVSKRICDPPNMLKHDFAEVERQMSEPSPDQPTVGGNTDALLGVDRSDLLGFGALVALWLITIVGGMTLADEAAAAGVVLFEDPSNATNVGLFAVYVLIGTAALLLGFRYANIVHLRAIGALIFGLFIGTSAAVATGVGSVARTGTLTGLPTSPIPIAVGVVAAVVLFVYPEWYVNNIAAVVLGVGFIPMFGLGFGPFPIVLLLVVWAGYDAYSVYVSGHMKELAAGAGDLKLPMLFVVPHSLSYSMAETGFDVGIDDTDEDATAESSTQTESPGAPDATAADATDAGGTTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXD0</accession>
    <name>U1MXD0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating</fullName>
            <shortName evidence="3">6PGDH</shortName>
            <ecNumber evidence="3">1.1.1.343</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00946</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH</text>
            <dbReference type="Rhea" id="RHEA:33023"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.343"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; pentose phosphate pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.343" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88800">
        <property type="protein sequence ID" value="ERG88800"/>
        <property type="gene ID" value="J07HX5_00946"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00115"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02047">
        <property type="entry name" value="6PGDH_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004849">
        <property type="entry name" value="6DGDH_YqeC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032883">
        <property type="entry name" value="6PGDH_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00872">
        <property type="entry name" value="gnd_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="4">
        <location>
            <begin position="165"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="172"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="118"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="31363" checksum="0CA3CFE963208CBE" modified="2013-11-13" version="1">MEVGLIGLGRMGRVILNRMLAAGHDVVAFDVDETAVDAAAAAGARPAGSIPALADQLADSKRIWLMVPAGDPVDDALAELAPALSAEDIVVDGGNSHFEDSVRRAETTDATYLDCGTSGGPAAADRGFSLMLGGSLDGYNALTPVFDAVATGPAGHAHLGASGAGHYAKMVHNGVEYALMQTYGEGFELLHRGRYEYDLETVAGVWNEGAVVRSWLLELCAEAFREEGSDLGDVADFVAGGSTGSWTVEEALEQEVPVPLIAQALAERFSSREDRFARRLANRLRYGFGRHDVRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXD4</accession>
    <name>U1MXD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_00951</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88805.1"/>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_00951"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="176" mass="19259" checksum="026124A49CA97E08" modified="2013-11-13" version="1">MSVAIQAADDVDAQVKKIASTRSLARIIPRINRVRMTVAALSIFQTSPSPSAQSIAPYRGDQRPRPGLTRLRRAVLTKPIERSSKPVWKRLNIQTSRSARFATGYCRSTRLKGWTSARYVSLGRRGNRTDRVPIGALFDCYSPLSTSLSVVVDSASCLSEPPRQPAAICPASISMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXQ4</accession>
    <name>U1MXQ4_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00934</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88788.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88788">
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        <property type="gene ID" value="J07HX5_00934"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="27327" checksum="0883052745FFBB81" modified="2013-11-13" version="1">MTNVTTVEAADDKRRGNTQAVYIAESLETEQLRERVDELVQYTDDVATVFDPSPRLTTRPSTASSPDGPTELSVLLALMDDGEFDEVMFSSWDMFGDLNELYQFLSGYVVDQRITIRFEPMPDLPFEIPTTEGAKRWKSFMTAVRIYNNLDMQQRRKEIAQRITAVREFDYHTGRPPLGFDSENGELVRLNRHRDICATLQMVDTGEVSKAAAAREPDCSRKAITRILQNRRNMYRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY00</accession>
    <name>U1MY00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01024</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88878">
        <property type="protein sequence ID" value="ERG88878"/>
        <property type="gene ID" value="J07HX5_01024"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047037_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="28546" checksum="D473FB940BD27667" modified="2013-11-13" version="1">MCTLVVAWQLFEEAPIVVAGTRDESADRASEPVSIRDWEATTVAPLDRRAEGTWIGANEHGVVAAITNRWTDANTGTGADTSNDGDGNSNGTRDSDRSRGLLVRDALGYETAEAAIRFVERDLDARTYAGFNLVVADQQAAMLVEHASARQVRPLEPGVHVVVNVGADGRYDLPETRRESGTERAVTGDTVHQTLRPEPGERAASWRARAEHALGDHTVGACVHGDGFGTRSATTLAVGPTGSVRTARHAPGPPCQTAFEPVMTNGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY44</accession>
    <name>U1MY44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01242</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89090">
        <property type="protein sequence ID" value="ERG89090"/>
        <property type="gene ID" value="J07HX5_01242"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1374732_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="21471" checksum="B87B0F80EADF379A" modified="2013-11-13" version="1" fragment="single">MINVSCRVQVSSVRHRLPTATGLTGRPLIAQRHVGAWLVLGFAIVMGLRSYYGLSGIGLTTWAIGDTSVANYMGVNYHVYQVAAEQAIAGESFYGVSPEPTTDAYVYLYPPITVAAFYPFTLFEWTTGYTVFIGLNVVIALVGTRLMLSYVESHGARLGWLDTALLAGLLLLSTHVVATVLYGNINILLGVVFAGGFWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY51</accession>
    <name>U1MY51_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="8">PRA-PH</shortName>
            <ecNumber evidence="8">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisE</name>
        <name evidence="10" type="ORF">J07HX5_01091</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88943">
        <property type="protein sequence ID" value="ERG88943"/>
        <property type="gene ID" value="J07HX5_01091"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123337_0_1_2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="13635" checksum="69FA1C07A9179770" modified="2013-11-13" version="1">MDTDTNADTDTTETETARGETGSEDNEIDAVIDNLFAVVEDRKQRLPEDSYTAELLTHEKGDNAVLEKLGEETTEFLLAAKGEDPDRMTSEAADVVYHLLVALVANEITAAQLRAELAERAEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY92</accession>
    <name>U1MY92_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Formyltetrahydrofolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01293</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89140">
        <property type="protein sequence ID" value="ERG89140"/>
        <property type="gene ID" value="J07HX5_01293"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1782447_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008864">
        <property type="term" value="F:formyltetrahydrofolate deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004810">
        <property type="entry name" value="PurU"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="4">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15666" checksum="1849CA725F139341" modified="2013-11-13" version="1">MQILSPEVVFRYQTRIINVHPSLLPAFPGAEAYRQAVEEGVRIAGVTAHYATTDLDQGPIITQRAFTVPPGADVETLEQRGQPLEAQALLAAVELHLADAVSVHHGRTQLRDTDTPADVQLGGPPALETARPSGPHDQHEQLSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYE1</accession>
    <name>U1MYE1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">K+ transport system, NAD-binding component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01189</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of a potassium transport system.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89038">
        <property type="protein sequence ID" value="ERG89038"/>
        <property type="gene ID" value="J07HX5_01189"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046525_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="139"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="229"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="364"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="445" mass="47315" checksum="137BB6976A8D9CAB" modified="2013-11-13" version="1">MRVIVIGAGQVGEAIASSLAADHDVVVVDTDTERVDELQYDHDVLTLAGDGTSLPVLEEAGAGSAERLIACTDDDRTNLVACGAAKTIGDPFTIARTKNVDYLRTWEESDAAFGANYVVCSTLLSAETIVRIVGLPAAVNVEPYAGGLVHMAEFEIDATSPVTDQTIAEADRFDSLTFAGLLRDGSAVLPGGETIIRSDDRIIVIGTPESVQQFAGDAAPNQTPDRADDIVIVGGSAIGYHAARLLEARGFTPRLIESDPDRARELAERLPDTLVMENDATDAEFLDRERVGDADVVVSALASDEQNLLVALLAQRLGSQQVIALVDNAEYVPLFEAIGVDATVNPRQATADEILRFSFESAAENLTVVQDNQAEVLELEIAADNNLAGQTIATLDDTVPGRFVVGAITRDRSYVVPRGETTLRDGDRVVVLADNDSVEALVDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYH7</accession>
    <name>U1MYH7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 2 lantibiotic biosynthesis protein LanM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01230</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89078">
        <property type="protein sequence ID" value="ERG89078"/>
        <property type="gene ID" value="J07HX5_01230"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_297482_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="174"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="1012" mass="111874" checksum="C1F4FF3DBAE2E44B" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYL3</accession>
    <name>U1MYL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01270</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89118">
        <property type="protein sequence ID" value="ERG89118"/>
        <property type="gene ID" value="J07HX5_01270"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2927743_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6173" checksum="0809F753E236BF7B" modified="2013-11-13" version="1" fragment="single">MGPRSRVIVVLLALAVCLGGVGVAVGQSSNGQGEERVVNVTNTTNQLSPAAVAADGYSFTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYM6</accession>
    <name>U1MYM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR00266 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01432</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89275">
        <property type="protein sequence ID" value="ERG89275"/>
        <property type="gene ID" value="J07HX5_01432"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1226995_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="225" mass="23687" checksum="15EE66D0D726147D" modified="2013-11-13" version="1" fragment="single">RPSYTHLQLTLERGETVVAEPGALVGHSTSISVETETSRDGLLSSAKSMLGGESLFTNEFIAEDGPGTVTLAPPTPGDVMAQTLTDETLYSTDGAFVAATSGIDIDSEIGGIKSVLGEASLVPLALKGTGTAFIDAYGGLEKLELAAGESYVLDNEHLIAWDDQIEYTTRRVGGLKSTLLSGEGVVFEFTGPGTAWYQTRDLDSLVEVLVPRLSDQDSGIDIETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYR1</accession>
    <name>U1MYR1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01468</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89310">
        <property type="protein sequence ID" value="ERG89310"/>
        <property type="gene ID" value="J07HX5_01468"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="27156" checksum="F04560D1578A2C76" modified="2013-11-13" version="1">MDPAAERAKMVTRLQQRGAIEEPETAAALRSIPRHEFVPDERQRLAYRDMPLPIGQGQTISAPHIVGRMAELLELDRGDEVLEVGTGCGYHAAVVAEIVGATLDDQTSRPVDTDAGGDPRSTHDTQRSRQDTDTAEPSDGRGMVCSVEYDATLASQARRRLTRLGYNVQVRNGDGRDGWPEHSPFDHGYLTCAVPEMPDAVVSQVRPRGYVLAPVGNQIQTLVRLQVTDSGLEKETFEQVRFVPVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYT7</accession>
    <name>U1MYT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01352</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89198">
        <property type="protein sequence ID" value="ERG89198"/>
        <property type="gene ID" value="J07HX5_01352"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088481_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="217" mass="23882" checksum="ADECBD519F8673CA" modified="2013-11-13" version="1">MHTFRDLETAVYCPRKLYYRRRAGDTSAVPDGDRPCRELAFEYERLLANTDHLREAPIVPTPTQYRSRLGRAKARLNWQRLVDPVEHEVVVTGRECCGIVDKLLAGPTVSLVFTGRPPAVGVRASQSVRLVAAAMALAHEYETTVDTTVAEYPAYGVIRPVDITPPRRAAYHEALAVADAVDGPPSRTQAGSKCKACAYSGRCGVRTRSLTSLLDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYU3</accession>
    <name>U1MYU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metal-dependent membrane protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01498</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89340">
        <property type="protein sequence ID" value="ERG89340"/>
        <property type="gene ID" value="J07HX5_01498"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073769_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="294" mass="31023" checksum="4059FB70A9999B58" modified="2013-11-13" version="1">MDAPVESDDITGEGPQQPEPQTIKSSLRVIGTAVFLAAVALLTPLISFGLIGAVVIIAFDPSLGSSARTAALVLATVAQFSWFVVVGLWYLRRRGFGWKQVRSYIGIERPSFRDGALILGTWLVMFIALLITAVIVTTVLLELTGTGAENQAENESLEFIDGGVSPLVILGVILGMFLVVGPAEETLFRGVIQGRLRERFSAAPAIGIASVIFASAHVFVLVGSPTARAAAVVVLFVPSLAFGILYEYTENLVMPILLHGFHNSMIVLGVYAGITAGSETVLTLVAGVLTGVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYW4</accession>
    <name>U1MYW4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytidylate kinase</fullName>
            <shortName evidence="5">CK</shortName>
            <ecNumber evidence="5">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytidine monophosphate kinase</fullName>
            <shortName evidence="5">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cmk</name>
        <name evidence="6" type="ORF">J07HX5_01383</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the cytidylate kinase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89228">
        <property type="protein sequence ID" value="ERG89228"/>
        <property type="gene ID" value="J07HX5_01383"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079959_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00239">
        <property type="entry name" value="Cytidyl_kinase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011892">
        <property type="entry name" value="Cyt_kin_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02173">
        <property type="entry name" value="cyt_kin_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="21668" checksum="B7B89CB7DBE458FF" modified="2013-11-13" version="1">MLITVSGPAGSGKSTLAAALADRLRHDHVSGGDLFRSMAAERDMTPVELNHAAEEDDQIDRDLDRRLRTTASDRDDVVLESRLAGWMAGEYADVRLWLDAPFDVRVDRIADRENKPVAQAKTETTARAESERRRYAAYYDIDVTDLTIYDLVVNTARWGPEETVSFVLRALDSYDAVADEGRMPVVGVRYEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ12</accession>
    <name>U1MZ12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89405">
        <property type="protein sequence ID" value="ERG89405"/>
        <property type="gene ID" value="J07HX5_01563"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039905_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="2">
        <location>
            <begin position="319"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="532" mass="56060" checksum="30A8041737A60F5E" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ24</accession>
    <name>U1MZ24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01578</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89420">
        <property type="protein sequence ID" value="ERG89420"/>
        <property type="gene ID" value="J07HX5_01578"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145184_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="16520" checksum="ECD684AC4E1510DB" modified="2013-11-13" version="1">MGLLGERPNVTIDRDEDPRLLCLDDEYTNEILQQLSSDTSQAVFRVVNQEPLSAQDVAEKLDMSIQNAMYHLENLEETGLITVLDTHYSERGREIEIYGPPDQPLVLFLGLSQDWSGLTAAFKKFAGAVGPVAVPLAIGQLLSRLFGSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ80</accession>
    <name>U1MZ80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01665</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89500">
        <property type="protein sequence ID" value="ERG89500"/>
        <property type="gene ID" value="J07HX5_01665"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712652_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="7676" checksum="BC9F3B53BBC2F66C" modified="2013-11-13" version="1">MSARTDPQDGARALFANPRLRAGLAVSNAALIIAIAFFFIDDTLTQLIMYAVAVIDAPVTIWVLGRVAETNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ90</accession>
    <name>U1MZ90_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">J07HX5_01680</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89515">
        <property type="protein sequence ID" value="ERG89515"/>
        <property type="gene ID" value="J07HX5_01680"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_4_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="129"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="266" mass="28673" checksum="36DAC3F5ABF0EC6B" modified="2013-11-13" version="1">MHAYRIAYDGREYHGFQRQPDVPTVEDGLLEALRSLDIGGSETPPESYAAASRTDAGVSATAQTVAFEAPAWLSPAALNSRLPETIRAWARAAVPASFHATHDATARQYVYHLYAPDTDPDRVRTLLDRLAGTHDFHNLTPDESGTTRNLSVGLRESSPFVELRVRADGFPRQLVRRAVGLVTEALDTGQARIDRALSPESLSGPAGISPAPPEPLVLTTVRYPEVAFTTDADAAARAQTLFERRRVSHATNAHVAAAIADAVGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB3</accession>
    <name>U1MZB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01711</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89545">
        <property type="protein sequence ID" value="ERG89545"/>
        <property type="gene ID" value="J07HX5_01711"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949145_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6122" checksum="508E2C186F4B75BA" modified="2013-11-13" version="1">MTMPSTPTQSTPPVDYSFASLALFAVLPIATIAALSAPKITLAFALGAVSAAALKRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZC2</accession>
    <name>U1MZC2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01721</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89555">
        <property type="protein sequence ID" value="ERG89555"/>
        <property type="gene ID" value="J07HX5_01721"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="27640" checksum="C79D6B7C21D5C54E" modified="2013-11-13" version="1">MRVVLTGAAGKIGRQVATRLLADGHSVVGLDKQPVALPEPAVTHVVDLSDSAAVRTLLEGHTVDAVVTAAGWYTIGALEDCSPAAFRDHLEANLVTAHTVINTTLPAVRRQSGRIVIVGSTTGSVPLPYHGAYSAAKAGLDGYATALRREVAEHGVTVSLIEPGPSRTGLNEQAAAARPDTGPYTDVYDQFEGYSPESTTPAAVAETAMQALTVTTPRGRYRVGRRAWWLPLLTSVLPTRIADRLVRAGLPDRLLGRLIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZF9</accession>
    <name>U1MZF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01587</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89428">
        <property type="protein sequence ID" value="ERG89428"/>
        <property type="gene ID" value="J07HX5_01587"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3038915_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="54" mass="6125" checksum="3E424A79B73C8A95" modified="2013-11-13" version="1">MSESNSKEYYELLVDDIAALQQRVDTIEDQLTALERPDEQALGAALDQEDSHRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZH0</accession>
    <name>U1MZH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01773</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89605">
        <property type="protein sequence ID" value="ERG89605"/>
        <property type="gene ID" value="J07HX5_01773"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2325476_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10259" checksum="22EF727E249E525C" modified="2013-11-13" version="1" fragment="single">AESDAAALTGFDGEALVLSFTGDWHFTTDQAADLTAAMQAVDIDVQHRVIDSDYGHDAFLVEPESVGPPIAAALASKPDETTDAGEHDTSAQACTPSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZH3</accession>
    <name>U1MZH3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative archaeal flagellar protein D/E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01602</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89443">
        <property type="protein sequence ID" value="ERG89443"/>
        <property type="gene ID" value="J07HX5_01602"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2379288_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006752">
        <property type="entry name" value="Arch_fla_DE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04659">
        <property type="entry name" value="Arch_fla_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arch_fla_DE" evidence="1">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="94" mass="10269" checksum="7D9702C1CFD3D20C" modified="2013-11-13" version="1">MIEQIPPGLGAEVLTLEWLSTLTAVAGPAGALRAVRHYEQIGWIGSTARRQIESLLASPSLDVFVDPTDPSEPTAGQHRRSYQYLVVLKTLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZI5</accession>
    <name>U1MZI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01790</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89620">
        <property type="protein sequence ID" value="ERG89620"/>
        <property type="gene ID" value="J07HX5_01790"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_770755_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043901">
        <property type="entry name" value="DUF5787"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19100">
        <property type="entry name" value="DUF5787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="360" mass="41068" checksum="6FBA8B21CA7D413E" modified="2013-11-13" version="1">MAVANSLRRQADTTGRRWTDVHEHEFGFELGVCQWAERHWPAPTTIVARQLGTTHRRWDTVVVEADPGGLAARAAFGDRRLDSDLLRVVRHAPAEWAWYRDALPEPSFPWRYVREAVNDAADRGLIDRRRRNGRVELRRRRPYPDWIDRVIAIENKPDLDASAARALGPQIEHDIALGLADEVWVATRATDETVEPVLLEDLPVEAGVLVAEPGRGVDRLKRVWEPRQLAVDQPGTRILDRPTGGEHDQSACQVEYADQSWKAGKRREIAERAYERGWRSYIQSMRPDCRHFELRPDAAVARPHCQAKDRCQRPGECAGSCPDFEPEPPGLRSQGWPIEGGPGQAIKRLLERQRDRTRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZK7</accession>
    <name>U1MZK7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01810</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89640">
        <property type="protein sequence ID" value="ERG89640"/>
        <property type="gene ID" value="J07HX5_01810"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="2">
        <location>
            <begin position="127"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Asparagine synthetase" evidence="2">
        <location>
            <begin position="263"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="374" mass="39898" checksum="BC05F14106A941DB" modified="2013-11-13" version="1">MTRRDATADETQPRSVRGAAPAAVEQSLRDRDPLPGTSGFAGRLEGQLVRDVLGRVPLFVDPVAGECGEWSHDPSALAAPRRVPAGHVWDDTGVEQIWQLPDLGPTRNHDRAIAAVGDAIETALASVDETGLAVAFSGGVDSALLAAALDAPLYTVGFPDSQDLVNARASADLLDRELQVVELDHADLKQAVEPVVRATGRTNAMDVQIALPIYLVAARAAADGIDRLALGQGIDELFGGYAKVVNAPDDPRIGADTVRGARRETVTTLPDQLERDSLTVRAAGVAPVTPLLHDAVVRAALALPGPLIAGEQRKQAFREATRAWVPEPIATRDKKAVQYGSLVARELDRLARQAGFKRRMDDHVTRYVESLVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZL4</accession>
    <name>U1MZL4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfatase A related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01649</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="PTM">
        <text evidence="1">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89488">
        <property type="protein sequence ID" value="ERG89488"/>
        <property type="gene ID" value="J07HX5_01649"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_14_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Ser)" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="304" mass="33184" checksum="93B656A5DC68DF5E" modified="2013-11-13" version="1" fragment="single">MNRPNVVLVVLDTARRDRVSAYGYDRETTPNFDQFATDATLYTDPVTQAPWSVPSHASLFTGAYPAEHGASTVRPVFGADAPLAERLRRGGYATAAVSANPYVRPANGFARGFEEFHGPSRPRGAAVPAPVVDKLSRITRPTVHKLTAARLRRPLERLFGLVKRRDAPTVGTNTDGPVADWLPAQVASVVARLSEPYFLFVNITTAHLPRSPAPAALERFVDPELRETPVVPNERTNALRDGLSERERQALTQLYDADLRTADTQLGEVLAIVDDAFVAVVSDHGEHLGEFGLVGHQYSVFEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZM0</accession>
    <name>U1MZM0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F420_ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01826</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89655">
        <property type="protein sequence ID" value="ERG89655"/>
        <property type="gene ID" value="J07HX5_01826"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2364345_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002847">
        <property type="entry name" value="F420-0_gamma-glut_ligase-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01996">
        <property type="entry name" value="F420_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_ligase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10292" checksum="ED3CDD636F799C5C" modified="2013-11-13" version="1" fragment="single">RYGQRGVALGWAGLPAARDWRGEHDRDGRELSVTVQAVVDELAAAANLVTGEGAGGTPVAVVRDWTFGDHAGSDQLFRDPADDLIRTALREWSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZT7</accession>
    <name>U1MZT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative efflux protein, MATE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01739</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89573">
        <property type="protein sequence ID" value="ERG89573"/>
        <property type="gene ID" value="J07HX5_01739"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_5_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="533" mass="55469" checksum="FA9B7791D4C759F4" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N061</accession>
    <name>U1N061_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01875</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89703">
        <property type="protein sequence ID" value="ERG89703"/>
        <property type="gene ID" value="J07HX5_01875"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149760_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14177" checksum="7B87B1E78E5A3CD9" modified="2013-11-13" version="1">MTPPASDRSAPVHTDDLALGCDACQAALATPGRDSISFLLTDHLTLPIVGCDEHLETFRAACALATTATAETLAHQPAGGVRCPACRLAHSTAQPVVPVTNGAVAVLGCPDHTTALIDRFHTGLEARRQLTASAKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0E4</accession>
    <name>U1N0E4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine-5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_02083</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89910">
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        <property type="gene ID" value="J07HX5_02083"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060704_1_0_2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="266" mass="28322" checksum="EC37462AB158AC9C" modified="2013-11-13" version="1">MSFFTRLADRVSRTDSVLSVGLDPAPGRLPDAVAGAELPRWAFNRRIIDATHNHAACFKPNAAFYEDSDGWRALEETVAYAHGKDVPVVLDAKRADIGSTARQYATVLETVDAVTVNPYLGRDSVDPFLQAPGGVFLLCRSSNDGAADLQTLELATGEPVYERVAALASDWGEDVGLVVGATAPAELEAVRAAAPELPFLVPGVGAQNGDPEAAVKHGLVDGVGLINSSRKVIFAGETARTRTSDEYFTAAGAAAKQLKRRLNRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P342</accession>
    <name>U1P342_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00038</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87897">
        <property type="protein sequence ID" value="ERG87897"/>
        <property type="gene ID" value="J07HX5_00038"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149757_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="52"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="144" mass="15573" checksum="DFEA62AE3EF5C825" modified="2013-11-13" version="1">MSELTAFSIEDLELVELTQETTEMGVNVNFPFTPEFPATTGHELEGGHNVVYFEIEPGKELGTHTDSPEEIIVCLRGDDIEAWAGEAEGTISGGDIAVIPPMAPHGFHNGGEETARFLGFFSDATNVSEFEEELQPMGETVVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Q0</accession>
    <name>U1P3Q0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00275</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88132">
        <property type="protein sequence ID" value="ERG88132"/>
        <property type="gene ID" value="J07HX5_00275"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1485876_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="157" mass="17560" checksum="E8A7F9B6EEF57C64" modified="2013-11-13" version="1">MSQTVLSSDHQLARLLQIGVVLEEVAEARAERYAAEPGVAPELAAYLRDAAQESATHRMRLNALTDQLNADTVPYEQIETLVGQRYEADTAFDGILYDQLCSEETAYKFYDDLIAALAGTDTRFTVDRRQIVTTLRSIRADEQAGVEKIARLMETME</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3R8</accession>
    <name>U1P3R8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative archaeal coiled-coil protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00300</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88157">
        <property type="protein sequence ID" value="ERG88157"/>
        <property type="gene ID" value="J07HX5_00300"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063607_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="34896" checksum="40452F65EC09BCE4" modified="2013-11-13" version="1">MTSSIDDSKNVSITDKEIETNSKGELIKLAGQLRDRRNDLNQMASERASTRDELNAKTREKVDEAQHHRERRDELNDKVQEHKEQRNELNATANELFEQVEEMKEDLKLDQGTDIEQLEQEIEDLEFKQQTEVLDADDERELIEKIESKRETLQEKKEKLDQNDELDELEAEAKEVRAKASEHHQKVTDLADEAQEHHNSMIEAYREADDIRDEADEMHENFVDAQEAADQHHEDFVQVQKRLRELDKEEEEAEREAREQEQEAAREEAEEIYQKFKEGETLETEDLMKLQKTGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4D4</accession>
    <name>U1P4D4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Molecular chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00496</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88352">
        <property type="protein sequence ID" value="ERG88352"/>
        <property type="gene ID" value="J07HX5_00496"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_2_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="594"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="621" mass="66356" checksum="C2D9FB79481654AB" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4F0</accession>
    <name>U1P4F0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00506</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88362">
        <property type="protein sequence ID" value="ERG88362"/>
        <property type="gene ID" value="J07HX5_00506"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2270943_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="11144" checksum="EEFEBADD78A51455" modified="2013-11-13" version="1">MSHRTTPPSGTGKTKSFNHSVEAANPWNRRTIRGSLRLRVCLDACLCAELEAAGETCETAQVRTSGTHLVDESTLQPTVAPCFLLNPGPGTRRPMWSSIEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4K6</accession>
    <name>U1P4K6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00587</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88442">
        <property type="protein sequence ID" value="ERG88442"/>
        <property type="gene ID" value="J07HX5_00587"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_8_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="10812" checksum="CF1C8BE1CAFF49C2" modified="2013-11-13" version="1">MSEQPAGDAPITLYRLQACPYCERVVRRLNELGLAFASEFVEPLHSERNVVKRVAGTRTVPVIVDDTTGVTMAESDNILEYLETTYADEQPVDPAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4X2</accession>
    <name>U1P4X2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00723</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88577">
        <property type="protein sequence ID" value="ERG88577"/>
        <property type="gene ID" value="J07HX5_00723"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="28319" checksum="440B5223F96AD92C" modified="2013-11-13" version="1">MTLPGATADRDEAAYAVIGAPLDRSTTGQPGTRFGPREVRELARGFEDYDHRTNQRFTDLSVHDHGDIGLRGDAREYLTFLESLVTAYASDGVVPTLIGGEHTVALGGIRALAPDIVVCLDAHLDLRAAYADDPLSHAAVNRRVLETANRVVVLGARAGSQSGWERAADSDVTVVKPAAVAGWTPPAETDQLYLSVDIDVADPSVAPGTGTPEPFGLEPATIHEIVRTVAPRAVGFDIVEVNDRDNGQAAVLAAKLLRAFVFAHAAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4Y4</accession>
    <name>U1P4Y4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M20 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00738</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88592">
        <property type="protein sequence ID" value="ERG88592"/>
        <property type="gene ID" value="J07HX5_00738"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_812608_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="112"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="341" mass="36434" checksum="7F42959CD4347651" modified="2013-11-13" version="1" fragment="single">DWTLCFNGHLDTVPFDETDWSRSPRGEQSEDRIYGRGATDMKGAVAAMTQLALAHAVTETTPPGTLRFIFVSDEETGGDAGLATVLERGIAPDACVVGETTARNGRVSVSVADRGRLFLTIAATGTAAHGSRPMIGENAIDKLYAAVEQLRSAFGQQRLAVDDAMDPIIDESVAFYEPETGADPARMLYQYPTINLGTIEGGTAVNTVPASASAQVDIRVTAGVDTEAILRSIRGCLDGMTGIELTDISWTRGTYEPLETSIVAASTRAAERVTDERVYRRSATGGGDAKLFRNDGIPTVEFGFGTQTAHSTDEYTTTRALVQNAIAYSAIPYEYDASLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P502</accession>
    <name>U1P502_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00758</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88612">
        <property type="protein sequence ID" value="ERG88612"/>
        <property type="gene ID" value="J07HX5_00758"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1901850_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004422">
        <property type="entry name" value="RFAP_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF6">
        <property type="entry name" value="PTHR20861:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="13272" checksum="E1E34EEC2BD372A9" modified="2013-11-13" version="1">MHAAVEGAAPEIADEISVLITRQLLPAVAEADLAAFGDAIARLGRLNGAWYANEQGGIYRPPAGEIVTALADSPVIAGAGQSSWGPAVYGVTQAATGDEAVTAAHAALTAAETDGQVQLVAPGNQGASVVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P537</accession>
    <name>U1P537_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00803</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88657">
        <property type="protein sequence ID" value="ERG88657"/>
        <property type="gene ID" value="J07HX5_00803"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954578_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="13797" checksum="EC5B9F59ECCB92DE" modified="2013-11-13" version="1">MCSSVTSDRTTVTTEESTLSGVDTVEETFDRLEPPRFAWCGPERQFVTGGAIKTVTAAGPERFQQLDAAAATLSTEAPPGGDRHTVPFVCGGRFSAAAAQDRRGGRFRPRCSLCRPPSWKPLATGYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6B5</accession>
    <name>U1P6B5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01254</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89102">
        <property type="protein sequence ID" value="ERG89102"/>
        <property type="gene ID" value="J07HX5_01254"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954581_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="5"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="12643" checksum="FB5EDB76081D7618" modified="2013-11-13" version="1">MLAGIGQVGFNIFQGGPGVVGASGAALALMGVLTVLKPDLTVYLYFLLPVPIWLLTGGTAVVSLGLIVFGMPGAFGIAHAAHFVGLAVGFLYGQRVKGRVRVPGQIQLGGPGGPGGPGGPGGPGRGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6D6</accession>
    <name>U1P6D6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L44e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl44e</name>
        <name evidence="4" type="ORF">J07HX5_01280</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89127">
        <property type="protein sequence ID" value="ERG89127"/>
        <property type="gene ID" value="J07HX5_01280"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114645_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01476">
        <property type="entry name" value="Ribosomal_L44e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_L44e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10814" checksum="A1033C4F9FC81C54" modified="2013-11-13" version="1">MEMPRRMNTYCPHCNEHHEHEVEKVRRGRETGMKWIDRQQERNAGIGNDGKFSKVPGGDKPTKKTQLTYRCNECGTAHQREGWRAGRLTFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6E8</accession>
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        <submittedName>
            <fullName evidence="7">FO synthase subunit 2</fullName>
        </submittedName>
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        <name evidence="7" type="ORF">J07HX5_01295</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="83"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="361" mass="39889" checksum="DF170853B7A1734D" modified="2013-11-13" version="1" fragment="single">MASSARVPTNVPRDRYEFDQRPTTDRSFEAALATARAGERLSVADGIALMTTGTDHPGIDRERKEKVLEAADRRRAAVVGDEVTFVANLNNNVTTACNTGCLFCNFKDRSETFRTGRGDHDGFTKTPAESRKTVAAAVERGIYEVTSVSGLHPAFALDDEHRERLEASGRPDLNYRPPEAYQTSPATYVDQIRAMSVDGVHLHSMTPEEAYHARRGTEWSYEEVYSRLKTAGLNSVPGTAAEILVDEVRDVICPGKIRSDEWVQAMEAAATVGLPTTATIMYGHVENEAHRVHHLAAIRELQDRTGAITEFVPLSFVHQNTPLYDRGMVDGGATADEDELMIAVSRLFLDNIDHIQSSWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P710</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="217" mass="22465" checksum="0D196F2B7C957682" modified="2013-11-13" version="1">MTDSERGAGDVPDVQAVAATIRENPAAATRTQVAMVADAVTADPDPETRRVATAALFATAEHQPETVASGVEQPRRLLSTDDETVLAWGTGTVGRVAEADPGWAVASAPVLQRLLDHDVQTVRHNALEALATVAIDRPDAVAPAAADLRSLLDADDVAVTHNAVGVLGVLAATHPDAVVPAVEDLAALGTHDERAVRRVATGALARLARERPDAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7V3</accession>
    <name>U1P7V3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01812</name>
    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89642">
        <property type="protein sequence ID" value="ERG89642"/>
        <property type="gene ID" value="J07HX5_01812"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="69" mass="7718" checksum="6C833CD8E8B191C7" modified="2013-11-13" version="1">MSIESAVQLTYLRASLAGATVRLITISSSFVPRPIKPLIRLCTVYTRSKSTASAYSYHKLTIRTINEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Y6</accession>
    <name>U1P7Y6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative hydrolase or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00404</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
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    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="185" mass="19631" checksum="F6D0C8CF12462449" modified="2013-11-13" version="1" fragment="single">MFAETTEHALYYETAGRSGGETITFLGEVGLGAWLWGWQQPRITGPYGTLVCDLRGTGRSDAPPGPYSIEGLAADVEAVLADAEVRRTHLVGAGLGGAVALRYAREYGRARSLVLFGTPPGGDDVDRGALETLIEPGSALSAGVSTAFLETVGRETIDEWRQADDPEPDAATAQPRHWSASTLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P814</accession>
    <name>U1P814_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease VII, large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00429</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88286">
        <property type="protein sequence ID" value="ERG88286"/>
        <property type="gene ID" value="J07HX5_00429"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243732_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11490" checksum="2C7E6E5DFC311216" modified="2013-11-13" version="1">MTLTTFDTESLVRAVAACSTPTVVAIGHEGDQSLVDRRLTGLGCRVEAGVNHLRQRCQQRASLRQRAVDLERRIDTVHRTAVTGRLGALETRIEHGLQTTELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P867</accession>
    <name>U1P867_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carotene biosynthesis associated membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01924</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89752">
        <property type="protein sequence ID" value="ERG89752"/>
        <property type="gene ID" value="J07HX5_01924"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070738_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017823">
        <property type="entry name" value="CruF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007354">
        <property type="entry name" value="CruF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39419">
        <property type="entry name" value="PTHR39419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04240">
        <property type="entry name" value="Caroten_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03460">
        <property type="entry name" value="crt_membr_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="32109" checksum="C23453B5ACCA14FE" modified="2013-11-13" version="1">MTKDGPTLSTPLPSRDELWRAVTDRQAAETLLDRMIMNNRFTIAVVFPIVGAVLLLASAEGVLPNPVAFNPLLVLTGVLVMRLPLVAGVVPLVDRRAGIALLVLTGYTYAIEYVGASTGWPYGEFSYEVALGPMLAGVIPVALPVFFLPLVLNSYLLSVLLLGERTKSVAVRLPVVAVVVVTVDLVLDPAAVALGFWEFGVTEFYGVPYANYAGWVLSAAVATVLIDVAFSRTALLDRLKRCSYMLDDMVSFVLLWGTINAFYGQWIPFGVAVLFAVGLVRVDRFDFVGLIPWRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8A2</accession>
    <name>U1P8A2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00495</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88351">
        <property type="protein sequence ID" value="ERG88351"/>
        <property type="gene ID" value="J07HX5_00495"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="22807" checksum="07B05516D7E84C76" modified="2013-11-13" version="1">MAADHGATLRYAIDTHVHADHVSGVRAVASETGAEPVVPAGAADRGLSYAATLVEAGDHLPLGETAAIARDLSGHTTETTGYRFDDVLFTGDSVFLDGVARPDLEDQSRAEDAAGQLWETVQALGDRDSNLTVAPGHVGPATDPGPDDTYTAQLAALRERLLAFEESRAAFVDRVTTGLPPRPANDKQIIAVNLGRETADHGTAFELELGPSNCAAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8F4</accession>
    <name>U1P8F4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02004</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89832">
        <property type="protein sequence ID" value="ERG89832"/>
        <property type="gene ID" value="J07HX5_02004"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_7_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="119" mass="12436" checksum="940D684025F3EEEB" modified="2013-11-13" version="1" fragment="single">MSTQTGSDRVLDVLAAEGTTTLFGLIGEGNTHLIDATNGHALDFEYARHEQAAVTMADGYARVTDEVGVCTLTHGPGVTNGATGLAAADRDNVPLVVVIGDTAFAGRETSLQYLDHQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8L6</accession>
    <name>U1P8L6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00616</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88471">
        <property type="protein sequence ID" value="ERG88471"/>
        <property type="gene ID" value="J07HX5_00616"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202927_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4482" checksum="64875707768F090E" modified="2013-11-13" version="1">MDPILITGLGVILLFVFFTYLLLRRTVQGFKNGVERGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8T7</accession>
    <name>U1P8T7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00697</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88551">
        <property type="protein sequence ID" value="ERG88551"/>
        <property type="gene ID" value="J07HX5_00697"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080904_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="16"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="227" mass="25023" checksum="FE4036476672BC3A" modified="2013-11-13" version="1">MADRPDTFDCTMTDWAHVYELCQTVATDVRAAGFEPDVVVALARGGWVAGRICCDFLGIDDLVSLKIEHYVGTGQKGDEPQIRYPLAEDAVAGKDVLIVDEIADTGETLRRAREYVADRTDRTVRAGVLQLAASSGVTPAFVGERLSEWTWVIYPWNLVENLIDLTTGILKRSDEVALSGPELQDRLITEHGVDPNAPQLDRLGAVIDEMARRELVTRADDGRVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8T9</accession>
    <name>U1P8T9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0146 protein J07HX5_02130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02130</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0146 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89957">
        <property type="protein sequence ID" value="ERG89957"/>
        <property type="gene ID" value="J07HX5_02130"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148458_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00341">
        <property type="entry name" value="UPF0146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005353">
        <property type="entry name" value="UPF0146"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03686">
        <property type="entry name" value="UPF0146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016725">
        <property type="entry name" value="UCP016725"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="136" mass="14587" checksum="789E6B5E0AA1A8BA" modified="2013-11-13" version="1">MQSNARALVARLAEVAHTQAVEIGVGRRPAVAAALADRGVTVVATDVHDRSVPETVQFVRDDVTAPRRSVYAGTDIVYARNLPPELHRPTVALARAHNAVCLFTTLGQDSPVVPVERTQLPAETLFLARAQTQSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8V9</accession>
    <name>U1P8V9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02150</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0440 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89977">
        <property type="protein sequence ID" value="ERG89977"/>
        <property type="gene ID" value="J07HX5_02150"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190390_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024502">
        <property type="entry name" value="DUF3194"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035954">
        <property type="entry name" value="MTH677-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11419">
        <property type="entry name" value="DUF3194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8781" checksum="F450E4252EF55140" modified="2013-11-13" version="1">MPADDQPAEAAVVDAAAAAAEQIIFSRYDRSAVRDLDITVQYRNKQLEVDVYLDVADDNNNAEQVADDAALAARGAADSLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9J9</accession>
    <name>U1P9J9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00947</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88801">
        <property type="protein sequence ID" value="ERG88801"/>
        <property type="gene ID" value="J07HX5_00947"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123922_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="13"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="17018" checksum="B053A14D2CB30121" modified="2013-11-13" version="1">MGIELSVDERWELLGSNAVARMATVDPNGLPHVVPIWYVAERGQGIYFSTPSDTAKVRHLEAKPKASLTVDEGESYFELRAVIAEGTVTELAEEAAARAERQWCQKYFDQPERSAAMEALYEGREWVWFRLDPGRWVSWDNSKIDRSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9Z1</accession>
    <name>U1P9Z1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-aspartate oxidase</fullName>
            <ecNumber evidence="4">1.4.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Quinolinate synthase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">J07HX5_01057</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88911">
        <property type="protein sequence ID" value="ERG88911"/>
        <property type="gene ID" value="J07HX5_01057"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_3_2_2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_2" evidence="12">
        <location>
            <begin position="11"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="521" mass="54272" checksum="F3F1D6330523A9C4" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA27</accession>
    <name>U1PA27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01104</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88956">
        <property type="protein sequence ID" value="ERG88956"/>
        <property type="gene ID" value="J07HX5_01104"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1207596_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="223" mass="23062" checksum="029027D5B7898EFF" modified="2013-11-13" version="1" fragment="single">IAALSTRIRPAVVVGAAGLSFGGWTALEIWFGQAIKGALPPASLDLIAGSLFLVFGLLLLRSIPDRPATGPTALPDGEPAETDGGLSAVADGLDLPGGRLAGPTGFGTFVSVFVLMATGEFGDKTQLITISLAIEYGAHPGIWAGEMLAIIPVSLANAYFFHRFAHRVNLRRVHVLSAGLFFFFAFDTFLALGTGVSVWETIVDTVGDLISGVVVGPLAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA78</accession>
    <name>U1PA78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01161</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89011">
        <property type="protein sequence ID" value="ERG89011"/>
        <property type="gene ID" value="J07HX5_01161"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1192637_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="12"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="224" mass="23713" checksum="A91DC69C34AFFC57" modified="2013-11-13" version="1">MNTAAEVVTSFSLGVATPLSAVCVIPLYPGFLAFLSNQDEDAPSIAVLGVLVALGVISFMAGVGVLFTTLLEQSLTTVVEFISPIAFGLLAVLGVVLLADLHPQQWLTTVEPPQSRSPALSAFAYGAFFGAIVLPCNPGFISVFFARAFLFSDPVFSIANFGAFGVGMASPLLGFAIVSEPWRDRVLNTLTSYRRTVNIVTGAVLLGISVYYLFFVFEIAGTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAP6</accession>
    <name>U1PAP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">PGF-CTERM archaeal protein-sorting signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01324</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
            <location evidence="2">S-layer</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89171">
        <property type="protein sequence ID" value="ERG89171"/>
        <property type="gene ID" value="J07HX5_01324"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930078_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030115">
        <property type="term" value="C:S-layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026371">
        <property type="entry name" value="PGF_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04126">
        <property type="entry name" value="PGF_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0701">S-layer</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6063" checksum="FB3B3C86DB5DBA5D" modified="2013-11-13" version="1">MTEQLTVQAGADGVDGDETGSDDDGAGPGFGIANVVAGASAVGYLLRRRIPARSVDQNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAS1</accession>
    <name>U1PAS1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01350</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89196">
        <property type="protein sequence ID" value="ERG89196"/>
        <property type="gene ID" value="J07HX5_01350"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1222488_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAT" evidence="2">
        <location>
            <begin position="95"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="25510" checksum="541F88C477FA0D6D" modified="2013-11-13" version="1">MARVIITARLYRTEVEGGLSACSRTQPDNSRQSHDQFEPTQTERRRTGSRKFGYDDMGEEQDYPSKQHYMHMTVIVRLTAAPSEFQLGRILDLQDGATVTLETLVPIDDQRVPSFRLFGSTRQEFGTEIERHPAVDKLEALTTTEDETLYALTWDASDDTFLTGIENMGARLLKGSGSNSEWSFEIRFPTHEAASRFQAYCTENGLQIDIDGVYNPTIPEAGIWGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAZ8</accession>
    <name>U1PAZ8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ORF">J07HX5_01423</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89266">
        <property type="protein sequence ID" value="ERG89266"/>
        <property type="gene ID" value="J07HX5_01423"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033144_2_0_2"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="54"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="309" mass="34048" checksum="CE188AA0A3142084" modified="2013-11-13" version="1">MSRSRKPEWLRMDLPSGESFTEIKQILRDRNLHTVCEEANCPNLGECWSGRGGDGGGTATFMLMGDRCSRGCNFCDVATGGMEPLDPDEPANVAAAVEAIGLDYVVLTSVDRDDLPDQGAGHFAETVQAIKDRHPGILIEALIPDFQGDPELVQKVVDAGPDVIAHNIETVKRLQRPVRDPRAGYEQSLSVLEQVATESDAYAKTSLMLGVGEYDHEIYQTLGDLRDRGVDIVTLGQYLQPSQTHLDVHTHVHPQKFETWRRVAETELDFLYAASGPMVRSSYKAGELFVDALLREGRSVEQARQAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBJ1</accession>
    <name>U1PBJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative archaeal flagellar protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01600</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89441">
        <property type="protein sequence ID" value="ERG89441"/>
        <property type="gene ID" value="J07HX5_01600"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134827_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42200">
        <property type="entry name" value="PTHR42200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="15433" checksum="4AC1DDC842A5B414" modified="2013-11-13" version="1">MAGGSVAELILFIAALSVAGGVAGVMVTTVNGVSDSIEEQADSAATDIKTEFTIISDPGTGAVYDATSDELTLLLKNTGSTSLPADEQVVEVLVDGQFVPSSAYSVTGLDTNRFRPGTVVRLTVDRSLAGGDHVATVTVRGTQNRVQFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBR7</accession>
    <name>U1PBR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01686</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89521">
        <property type="protein sequence ID" value="ERG89521"/>
        <property type="gene ID" value="J07HX5_01686"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2032784_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="12947" checksum="D19410D0B7353C7F" modified="2013-11-13" version="1">MRTSRLTRLSGYSSNWPRHSGPPAAAGYPVGYADDTRLAPADRGRSLVPDAVLRCCSATTVWVRLFSVRVCGVAIPSSDLDASPMLEYTIVRRILRGLTLCGLLALTGANGSLADRIVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBW9</accession>
    <name>U1PBW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase of the beta-lactamase superfamily I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01742</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89576">
        <property type="protein sequence ID" value="ERG89576"/>
        <property type="gene ID" value="J07HX5_01742"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044538_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="54"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="293" mass="31554" checksum="D8642BEC37550260" modified="2013-11-13" version="1">MEVTLLGTGDTTGTPTVGCECETCCRARSPSPALRDRLRDNGATITAGGGVERTRFAVLVRNERTDKSLLIDFSPDFRQQFLREGVSPPDEAVITHIHFDHLDGLGNVYRLLRSIDVHAPDELDPATGASVAETVATDYAYLDPVTVRPETPFEPFTACGFELTLVPVEHPPLACYGLTVVEPETGVKLSLTGDSAYNIPDQSRAVLSDPDLLLADALVPASLCDKHPLGGAHHDADGTPRTFGTKHMTREGALSLAEELDANQTRLVHIAHFYPAAEAFVSPLAVDGEQFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCB2</accession>
    <name>U1PCB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxycytidine triphosphate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01898</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89726">
        <property type="protein sequence ID" value="ERG89726"/>
        <property type="gene ID" value="J07HX5_01898"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1083721_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010550">
        <property type="entry name" value="dCTP_deam_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06559">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01445">
        <property type="entry name" value="intein_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0651">Protein splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HintN" evidence="4">
        <location>
            <begin position="116"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="28078" checksum="938A76270EC85B5C" modified="2013-11-13" version="1" fragment="single">MILSDADIRRRLAEGELAVEPLADPDLQIQPASVDLRLGRTFLEFQHTNIASIHPDSEREIDEYVSETVVDEDEEFILHPDDFVLGTTKERVEIPPDLIAHVEGRSSLGRLAVVVHASLPYQEEVFLWTPAEGFGFYEIGAIVENERPARAVSFDPQTLAVGTYRVTDHITNPTKRIYRVRLQSGREVTVTKDHNLFTLDNYGGVTRVPSEDAEGAHVMVPATLPASPTESETLGVHDLADTAGTTVSAAATPGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PD03</accession>
    <name>U1PD03_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02144</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89971">
        <property type="protein sequence ID" value="ERG89971"/>
        <property type="gene ID" value="J07HX5_02144"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1393539_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="195" mass="20947" checksum="CE4C958DE191F36E" modified="2013-11-13" version="1">MTATGSASAVRASVSWAIGNHCLRCSCSGPYCVVGDESLIEIRRNGRVMTERRHATDLIAERRLNLRRGGESSCVHAVRAACDNDDQLVGSKRERTRNLCPVTANSAGGVSGGLSAGRELLDVNLDVMIALGATAERRGLLVHIHRYLGHQLVVCRRRRLCHNPGKRGHPRVSDPLAARPQASADPVSASKAAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG60</accession>
    <name>U1MG60_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="2">N5-CAIR mutase</shortName>
            <ecNumber evidence="2">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purE</name>
        <name evidence="4" type="ORF">J07HX5_00332</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88189">
        <property type="protein sequence ID" value="ERG88189"/>
        <property type="gene ID" value="J07HX5_00332"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094982_1_1_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="3">
        <location>
            <begin position="37"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="23026" checksum="EA35623AAD766FB9" modified="2013-11-13" version="1">MTTDDTNATDDDTNPVASLIEEFRAETDQDRPPEATPEIGVVMGSDSDLEAMAGAHKALSRLGFAETTDRDKPPAKRFSFESYVLSAHRTPDLMYAYAETAADRGLEVVIAGAGGKAADLPNMVASIAYPLPVIGVPIQEKSVDSVVGMPTGAPLLAVDAGKSYNAALSAAQILAREHQVLRQRLTALRANRRSEVAAVSRALHEQGTPAVRDGSDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGA5</accession>
    <name>U1MGA5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00382</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88239">
        <property type="protein sequence ID" value="ERG88239"/>
        <property type="gene ID" value="J07HX5_00382"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3413617_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="28" mass="3233" checksum="BDA97CB2BEBBCDF1" modified="2013-11-13" version="1" fragment="single">DAMAEPVVVDGRRIIERREGITYEGLTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGG4</accession>
    <name>U1MGG4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00448</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88304">
        <property type="protein sequence ID" value="ERG88304"/>
        <property type="gene ID" value="J07HX5_00448"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1790846_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="16966" checksum="788364AE6C591EF6" modified="2013-11-13" version="1" fragment="single">MLDASASLWNELNYERRQQFFNGESVWDTADYRKQYVDITGSATAQQLIRKNTSAWQSFFSLHEQWQNGELDERPSPPGYWGNEDDGRELRTFIRNDSYTLETGNRSRIEIPVGSQLKDEYDHTGRLRLELCGVPKWDGEQGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGU0</accession>
    <name>U1MGU0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00589</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88444">
        <property type="protein sequence ID" value="ERG88444"/>
        <property type="gene ID" value="J07HX5_00589"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2433730_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9768" checksum="D01F2383AC01FA89" modified="2013-11-13" version="1">MRPVLETTAVVAPTQVTVRETTTPAETESNCSGSAGHHSRLLCCMCIFMRQRLAGDHIVRIRKTGRSNPAYKSVEMQSLSVLLGGSIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGX3</accession>
    <name>U1MGX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase, P-type, transporting, HAD superfamily, subfamily IC/heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00639</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88494">
        <property type="protein sequence ID" value="ERG88494"/>
        <property type="gene ID" value="J07HX5_00639"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="831"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="9">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="9">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="867" mass="91660" checksum="42ADE177E1CAB43B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH20</accession>
    <name>U1MH20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00715</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88569">
        <property type="protein sequence ID" value="ERG88569"/>
        <property type="gene ID" value="J07HX5_00715"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1700249_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010115">
        <property type="entry name" value="FbiA/CofD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43007">
        <property type="entry name" value="PTHR43007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="187" mass="19511" checksum="3E66E5299DED99DF" modified="2013-11-13" version="1">MTDELAAAFDVPWELVPMSDDPVATIVHTPDGPIHFQEFWVAHGGEPAIDRVEFRGADTARPTEAVMTALEQPVVIGPSNPITSIGPMLALDGVETALTATPVVAVSPFVGDKVFSGPAGELMTAAGYDGSTAGVAEAYPFVDAFVLDTADDTTLDRPVVRTDTTIETETDARRVARAASDALGAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHU3</accession>
    <name>U1MHU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cellulase M related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01035</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88889">
        <property type="protein sequence ID" value="ERG88889"/>
        <property type="gene ID" value="J07HX5_01035"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047249_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="350" mass="36805" checksum="F0384CE879AA643A" modified="2013-11-13" version="1">MTVPFDYELLAELTETSGVPGYEDRIREIVRRELEPHVDAIRGDGMGNVVGTIDGATDTTVVVAAHMDEIGFMVRHVTDDGFVQIDPLGGWDASVLKAQRVTIHTDDGDVTGLIGSPPPHTLDEEAREGAPDVEDVSIDLGVDGETAAERVSVGDLVTLDQTTEQVGEHITGKALDDRVCLFAMLEAAKRLTDPGVTVHFAATVQEEVGLRGARALGDDLTPDIGIALDVTVANDVPGFGPGEHVTNLGSGTAIKLKDSSVITNPKIAGRLQTLADSEGIDYQTEVLPAGGTDTAGLQVPGGATPVGALSIPTRYLHTVTESAHIDDIAATVDLLTAFLDTESPDNDYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHX7</accession>
    <name>U1MHX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type multidrug transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01081</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88934">
        <property type="protein sequence ID" value="ERG88934"/>
        <property type="gene ID" value="J07HX5_01081"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="34"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="252" mass="26706" checksum="E86D3292538D5F5D" modified="2013-11-13" version="1" fragment="single">MSTPSVDGTDGESPSQAAVSQPEVDAGNGFLGDVWVNFKRWNLKAIRNPFVLFISLVQPVIFFVLFTQVFGNVAGGAVGRDISGISYETYLIPAIAIQVSLAAAITSGVGLVNDIENGMFEKVLVTPMNRTAVFLGKTAAEVFRIAVQIAIILGLGLLFGAEIATGIVGAVGIVAIGVLFSLWFIAFSNALAILTRDQESTIIGANLLQFPLLFLSSAFLPLAVLPDWVQTFARVNPVTYGVDAARSLIVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI57</accession>
    <name>U1MI57_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Peptide chain release factor subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Translation termination factor aRF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prf1</name>
        <name evidence="11" type="ORF">J07HX5_01195</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89044">
        <property type="protein sequence ID" value="ERG89044"/>
        <property type="gene ID" value="J07HX5_01195"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035759_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00424">
        <property type="entry name" value="Rel_fact_arch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_1_Pelota"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020918">
        <property type="entry name" value="Peptide_chain-rel_aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PTHR10113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="SSF55481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03676">
        <property type="entry name" value="aRF1/eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1_1" evidence="10">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="414" mass="46187" checksum="2BAB37993C139D54" modified="2013-11-13" version="1">MSEMEPEQSDKRAYEFRKVIEELSEYRGSGTQLVTIYVPEERLISDVVAHVTQEHSEASNIKSKQTRTNVQDALKSIKDRLKYYDTRPPENGIVLFSGAIDAGGGQTDMITRVLESPPQSIESFRYHCDAEFLLEPLAEMLTDKGLFGLVVLDRREANVGWLRGKRVDPVKSATSLVPGKQRKGGQSAQRFARLRLEAIDNFYQEVAGMANDLFVPERHELDGVLVGGPSPTKDEFLDGDYLHHELQDNVLGKFDVAYTDESGLYDLVDAASEILAKQEILEDKAVMEEFFKALHDGDVATYGFGPTRQNLIMGSVDRLLISEDLRREAVRYECPNDHEEHEMLAPGESTTHTCSRCGEPADPSERTDAIDHLMTIADQRGTETVFVSTDFEKGEQLLSAFGGVAGLLRYSTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI60</accession>
    <name>U1MI60_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01200</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89049">
        <property type="protein sequence ID" value="ERG89049"/>
        <property type="gene ID" value="J07HX5_01200"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2010029_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="13385" checksum="AAA8BFFC11188ECE" modified="2013-11-13" version="1">MVDNMIGDVVVYNERASQTNGELRLTDPTGSVRVNEPFEVVSPSAADDDENMAPFKNVWTTDGSYEVSLELTKTDIDGADSMIETVSVANPEKEMLIVRLSADGPGDPINFCVQNNFEPISKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI68</accession>
    <name>U1MI68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01210</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89059">
        <property type="protein sequence ID" value="ERG89059"/>
        <property type="gene ID" value="J07HX5_01210"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079334_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="11802" checksum="86AFE11594AF98C9" modified="2013-11-13" version="1">MKVATVGIGQAGGRIATTISSFSSRFYSASSFVGPVAVNTAEADLAALDLPAEQTVLIGVDRLNGGGVGTDNHLGAEVTETGIGAVHDSIDQLPIYTVDAFLLSPDSAAERGQVASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIA0</accession>
    <name>U1MIA0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01256</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89104">
        <property type="protein sequence ID" value="ERG89104"/>
        <property type="gene ID" value="J07HX5_01256"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008213_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040699">
        <property type="entry name" value="XPB_DRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18458">
        <property type="entry name" value="XPB_DRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="87"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="324"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="451" mass="49789" checksum="F89A83F699DA74D6" modified="2013-11-13" version="1">MSDVSLSYDDGTIRIEGSQALDEQALGDAVVYDERSQTGRVPAYQYGPVRNALAQRSVSVTDNVLAVPTVTFSSDYRLRSYQQQALESWNAAGRRGVLELPTGSGKTVIGLAAIEACATSTLVVVPTIDLLEQWDRELAPAAKDSVGRLGGGEQRVADLTVATYDSAYLRAAELGDRFGLVVFDEVHHLGAEGYRDIARFLAAPTRLGLTATFERPDGAHEVVAELLGPVVDRLTPEELAGEHLAPYDIKRIAVELTPEERETYERHQGTFTDYLAESNLSISSGAEYQQLVKRSGTDPQAREALLAKQRAKAVTTHASRKTERLRELLARHHDDRVLVFTTSTELVYKLAERFLMPAITHETGADERHAILDRFREGTYTRIITANVLNEGVDVPDANVAVVLAGSGSQREFTQRLGRILRPSDDRGRARLYELVTTDTAEMRVAKRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIB9</accession>
    <name>U1MIB9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor 2, alpha subunit (EIF-2alpha)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01282</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89129">
        <property type="protein sequence ID" value="ERG89129"/>
        <property type="gene ID" value="J07HX5_01282"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033458_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="PTHR10602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="SSF110993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="SSF116742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="10"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="266" mass="29284" checksum="CF20CDEF4A9FF961" modified="2013-11-13" version="1">MKYSGWPDPGELVVGRVDEIEDFGVFVDLLEYNDKQGLCHISEVASGWIKNVRDHVSPDQRVVAKVLDVDQDAQQIDLSLKDVNDHQRKEKIQEWKNEQKADNWMEIAFGESVGDETYAGIVNALLAEFGSLYDGFEAAAIHGPEALAPVDISDDEAAAIVETAQKNVSVPYVTVTGYVDLESAERDGVDVVREALQSAEGNGEVPEEATLEVTYVGAPEYRIEVQAPDYKTAEAELEASAQRAVRVVSDHEGTGSFHRERSTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIG9</accession>
    <name>U1MIG9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01348</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89194">
        <property type="protein sequence ID" value="ERG89194"/>
        <property type="gene ID" value="J07HX5_01348"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1425051_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="20583" checksum="DDA83C02066853DC" modified="2013-11-13" version="1">MIRNDGGTGRVGIVTPPELGIFDAVIEGDADATWVFMPWEGLLAERAGVELNAFYLDEYEIPYGYTPTMVARPETVADRADELAAFLGATGRGYRDATAAPATAAATLAETASPDPSDEEFLTESHHRLADAFLTDDGNWGLMSHDRWATFVDWLATENILTTVDETSLPATAVPPVELYTNELLREATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="4880" checksum="E41DF3E179A0E5BE" modified="2013-11-13" version="1">MFTNERICLACVIELFYLHESVGNPSYMDAEKFACEVRSSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIJ0</accession>
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        <name evidence="1" type="ORF">J07HX5_01379</name>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="705" mass="76869" checksum="BF15FD5D0D7AC227" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJD4</accession>
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="111" mass="11675" checksum="232E5D84E5E510FC" modified="2013-11-13" version="1" fragment="single">LFADSVLDHRGDTIEISRSELLEANSYLGVEAVENGIADELGFTETATRDVANKAGLDSYEIVTFESSGFGLGLFAGSEQLQTSGPPYFAVDPSMIAVHNGTVTMVGGDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJS8</accession>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="30" mass="2766" checksum="7401E20E14AC4CD6" modified="2013-11-13" version="1" fragment="single">MPRAPSTAAGETAGVSLAVVAGAVVVLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK80</accession>
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        <submittedName>
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        <name evidence="9" type="ORF">J07HX5_02132</name>
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    <organism evidence="9">
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
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        <location>
            <begin position="140"/>
            <end position="233"/>
        </location>
    </feature>
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        <location>
            <begin position="260"/>
            <end position="299"/>
        </location>
    </feature>
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            <end position="289"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08442"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="30850" checksum="8B7FB97FC20E0404" modified="2013-11-13" version="1">MVSDAGGTSIETVAAEQPDAVVREPIDPAFGLHEYQARRAVFAAGVDRQASAVSDSLGTLYELWAAHDGLAAEINPLVLTSDGVVAVDAVLSVDDNARWRQPDLAEYAPSPSPTDSVAAQAATHDFDYVQLDGDVGVIGNGAGLVMATLDQIDDRGGSPANFLDIGGGAGPERVKNALKMLFEDETVEAILFNVFGGITRCDEVARGVNDALSALDNVTKPTIVRLAGTNAAAGRALLDPTVYVADSFGDAVATAVAAADKTGASSGSLDPDTIPDPDPDRESRSDSRPSLGPESEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MUZ3</accession>
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        <recommendedName>
            <fullName evidence="2">DUF5786 domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">J07HX5_00016</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043902">
        <property type="entry name" value="DUF5786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19099">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5786" evidence="2">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6590" checksum="E65147AAF5468937" modified="2013-11-13" version="1">MSLGAYDDDEHERRERKNSEVNASFDDVREEYNGSVEFEGEGSTEALLEQYERITGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV85</accession>
    <name>U1MV85_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00146</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88005">
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        <property type="gene ID" value="J07HX5_00146"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066581_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="376" mass="42039" checksum="E4A3406C9662F9CC" modified="2013-11-13" version="1">MTSCSICGSDITTTDVFCTXXXXXXXSTNIYAPYLFVGIGIIVAFGFLPTYGYITTGFHSALANPLRPMVISAGLIFSVVSIRYMMDKYAQAISRLDLNQRQLTLSHSQFKGIVSLRSKLLVYGLTLAVYYLSVIIPSVIQILDIDTDITLLTALSGRNIQTLIETEGLITTIVGQLIIVPLVNVPVILEFVILFFGVHLILPNRISQANFKLFFHDPRNMGGLNNIGQLLKQSYYLYTGGVLLYFVVAYGPVIFSYLISTPRPTPGTDVVALFSLIWIIGLGSVIYSFYKIHRIMASEKERRLNEIESDIKTLIENPFEVRSSRVTNKEAMDTKERQLRQIQSTKTYPATFTMWWQLGLSVLLPQALQLAVQGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV87</accession>
    <name>U1MV87_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00151</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88010">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024992">
        <property type="entry name" value="DUF3891"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13030">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="286" mass="32287" checksum="CFC93B1306EA2F2F" modified="2013-11-13" version="1">MIIATSADGYRCITQHEHSKIAGRCALAWGNKEFSSPTPEESVVTATFTHDIGWREFDQRPRLNTDTETGNPGLINFHEVPAQTWVEMYEQGIETVAELDPYAGLVVSLHGVGLQTRRYGLTPEWNKPGEAFRAFIENEQQRQQQLLERIADQAGDNVSAEDRTTLARLHDNNQTPERYTGRLWCNYKLLQFWDTLSHLLCATTDQTVDTTIEHAPVSVGADVSIRVHSETATTYQLEPYPFSRDPLVIPAVARTVSEQTINAESEQAIAREYFASTTNIEFRLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVB2</accession>
    <name>U1MVB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00181</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88040">
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        <property type="gene ID" value="J07HX5_00181"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2010041_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="15234" checksum="B268D757A3234DD2" modified="2013-11-13" version="1">MIRRLLHAVGYLIAHVLFVDAETPTSVVRRLRVAYRLVGVRIVETPTVDDTEQTIFLCPYRNIAAGRLGQYQFCHDILDRVDDGYVTFLRRHRGIDYQRPRGCTELAGASSPYCYSEVEVEAKAETGAEAAVTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVE5</accession>
    <name>U1MVE5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00074</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87933">
        <property type="protein sequence ID" value="ERG87933"/>
        <property type="gene ID" value="J07HX5_00074"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_15_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="111"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="38627" checksum="AE946C7CC05C732B" modified="2013-11-13" version="1">MSETHQDHVGYFLEDITNQGKSPRTRDAYERVLRDFEGYLEGRTLGFAAANHRDCLAYVHRLRETTTDSTVATYSSYLHRFYDYMVRVGELEDNPMAVVIEEIDESIATDPPRRELTVAQMRSFVAATAHPLDRAVIVTLLKTGIRAGELCNLDARDLNLADHTREADPRPRLDGRPHSVYIDSTPAQGSVYNGQRRTASNKRQRATTIPIDDELAAVLERWLAVRPDPISDANPLFMSTTNSWGRRLTTDMIHHIVETHAREAGWYRDGGGPEENVTPHYFRHFFTTHLRDRTGDRGVVKYLRGDVANDVIDTYTHDWGDTVRYAYDSHIYSVLTTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVI5</accession>
    <name>U1MVI5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00119</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87978">
        <property type="protein sequence ID" value="ERG87978"/>
        <property type="gene ID" value="J07HX5_00119"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_44_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7644" checksum="41FA9A0181AFAE8B" modified="2013-11-13" version="1">MNNTLRENREETGLSQADLADAVGVSRQTINAIERKRYDPSLELAFKLAEQFDCQIEELFDPVLDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVN4</accession>
    <name>U1MVN4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00318</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88175">
        <property type="protein sequence ID" value="ERG88175"/>
        <property type="gene ID" value="J07HX5_00318"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128030_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13474">
        <property type="entry name" value="SnoaL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14368" checksum="02025AE87522968D" modified="2013-11-13" version="1">MNADETIAAYYDALREGEPLGPYFAEGQPDDDALVKYGLSERLVGDTEIRAGLKHQTETTTDWAVTSHALQVCSRDTHAWFSDTVSMAWTDIETAIRYEFETRWSGTLTQTADGWRFVGMHVSTADQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW05</accession>
    <name>U1MW05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ATPase, RNase L inhibitor (RLI) like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00449</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88305">
        <property type="protein sequence ID" value="ERG88305"/>
        <property type="gene ID" value="J07HX5_00449"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017344_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="PTHR19248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="71"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="340"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="110"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="377"/>
            <end position="384"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="589" mass="64951" checksum="6E7B780B3B155035" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW20</accession>
    <name>U1MW20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00464</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88320">
        <property type="protein sequence ID" value="ERG88320"/>
        <property type="gene ID" value="J07HX5_00464"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1639903_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="161" mass="16703" checksum="3835BB06FBB2A927" modified="2013-11-13" version="1">MKPASKDWNEVSPTDITLQFALTADDNGQWKAVSTVGVSFHSGPRALSSNEIRVDTYTKDSNDEIGVVRKETAERPDVGDVGTDGLGCEGWHIVVGAICAGVNGSLGPKGCISRCIPIVISNPFIGTGCAGLCLALTHELGMIACGSGGLSTAICKTIDYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW28</accession>
    <name>U1MW28_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="8" type="ORF">J07HX5_00331</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88188">
        <property type="protein sequence ID" value="ERG88188"/>
        <property type="gene ID" value="J07HX5_00331"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_2_2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="126"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="195"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="279"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="471" mass="49065" checksum="D8DD516DBA2CAAF8" modified="2013-11-13" version="1">MTDLLAGSPPASVPDAVAVPGATVGIVGGGQLGRMAAEAASPLGIEIVVLDPTPDCPAVPPATEQIVGEFDDTAAMTELAGRADALTVEIELADPDAIATAGADAGVPVHPTPETLRTVRDKLLEKRRLADAGLPVPSFRGVDDAADLRSAFEELGRPLMLKARRGGYDGRGTAVVESVTDAEQAFGELRGTVAESLVEFARELSVIGVVGADETRTYPVTETVHEAEILRQTVTPARTTATVRKQAQRVATEVLTMLSGRGVYGIELFETTDGKILVNEIAPRPHNSGHYTIEGAVTSQFEQHVRAVLGLPVGGTELRCPTAVGNLLGDTDQERLLTHGNRSGNGQSAGSPASQPADAAVATGPDSTGLDSGTTPTAAIEGTAQILTAPDTAFHWYGKRTVRPLRKMGHLTVVGEAGALDDEHTGDDTAEPATRVGPRSNRGGSRPDPTELLERASELTDAVRFTPVTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW85</accession>
    <name>U1MW85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00391</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88248">
        <property type="protein sequence ID" value="ERG88248"/>
        <property type="gene ID" value="J07HX5_00391"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="311" mass="33550" checksum="7E1D18B77637E9E5" modified="2013-11-13" version="1">MDIVRTEKLTKHYGDVVAVEDPELHVKQGEVYGFLGPNGAGKITTINLLLGLVQSTREDVQVFGKDLSINSRLIRSQIGVLPAHAKPYDRLTARKHVEFVSRGKNADVEPDALLERVGIPDAADRPAGEFSTGMGQRLKLAMALVGEPELLILDEPTNGLDPNGARQMREIIQAENDRGATVFFSSHIMGQVEAVCDRVGVLNEGRLVAEDTVEEIRTVASGGAELLVTVDSGADRVAKRIQTANSVSAVTIDQQTQTVAITLNGIDDKGRAMTAVAEAVVGTNTQIRDFELREETLEDAFADLTQTEVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWE6</accession>
    <name>U1MWE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-finger containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00585</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88440">
        <property type="protein sequence ID" value="ERG88440"/>
        <property type="gene ID" value="J07HX5_00585"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085607_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="242" mass="26294" checksum="B80B92DF454A5191" modified="2013-11-13" version="1">MSDFDKEAERERLREQYERDKQEREAAEQMSELLLQGATMTNAHCSECGDPIFRYDGQEFCPTCERPVSRSDNRQATADDETTAPDDETGSADGDDETIEVTTPSDDARVAFGGVDDPDSSTADTQTNTGVSPDARSDAGTGRSPAPDRGHEHEHDQSRDKDRRQTETEESAATRSRSQSRSSAPAATAPETDTATATARESLTQALIRFSEQAAATDDPRRAQDALAAAREAAEALAALRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWH0</accession>
    <name>U1MWH0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N2,N2-dimethylguanosine tRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00615</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88470">
        <property type="protein sequence ID" value="ERG88470"/>
        <property type="gene ID" value="J07HX5_00615"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1258399_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004809">
        <property type="term" value="F:tRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="PTHR10631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="221" mass="24105" checksum="F379DA3E0BC30E90" modified="2013-11-13" version="1" fragment="single">MRVTEGAVEIEVPEQSAGAGDEVFFNSEQQLNRDLTVAVLRAYRERDDRATTYFDATAASGVRGLRAAADDWTVTCADTDPDAVALARANFARNELTGTVEHRSAIPLLHESYFDIVDLDPFGTPMPFVDAAVQGTRDLLCVTATDTAPLCGAHFEPGVRRYSAVPRNTEYHAEMGVRVLLSAIARTAARYDVAVTPLVTHATRHYVRTYLELDRGASVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWN0</accession>
    <name>U1MWN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane-bound metal-dependent hydrolase (DUF457)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00696</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88550">
        <property type="protein sequence ID" value="ERG88550"/>
        <property type="gene ID" value="J07HX5_00696"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_843631_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="302" mass="30430" checksum="0C889E8A84A0B62A" modified="2013-11-13" version="1">MFLGHGLAAFALAASLAAYCGWGDDRALAVGLVAGLFATLPDVDVVYTAGGFLTAQITGPDSFWGVANELHRGITHSLVVGAAATLGFAGWRARTTAWRGLAATLVLTGLVGLGLTAGPAVGAVMLVFVVVGVGIVRVAELLLLGPRVVLATAGLGLGTHPFGDLLTGSAPAVLYPFEPLSLSRIALHPDPTIHLLGSFAVELAVVWAALVVGVAVGTETQLRDHVQPRAALGISYAAAAVVVPAPTLDLALPFVASVLSVGIIAAPVRAERPRLLTLFGTALTAVTLAAAAYAVVYLAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWN8</accession>
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        </submittedName>
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    </gene>
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            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88560.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88560">
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="47" mass="5530" checksum="3A659446286D5EE2" modified="2013-11-13" version="1">MTKQLKVSDAVYDDLDELKDEEGHTSFDSVLRTLLLHYRHVQPNDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWU2</accession>
    <name>U1MWU2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00588</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88443">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00578">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="16"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="170" mass="18834" checksum="4017892C49D27DFD" modified="2013-11-13" version="1">MATNFDLTQLGPADHPSVGELAPGFQRPLVDDESWADIALSELVADGPIALVFFPMDGAFPATYMWTELRDRAWTDRSATVVGVSVSSPYEHSTFIDRYELPYRLFSDPGNDIAETYGVVHDLDGMAGVTEPRPAVFLIDDNQTVQYAWAATEWPSFPPYDEIEAAIDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX37</accession>
    <name>U1MX37_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00856</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88710">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="172" mass="17584" checksum="2D478FA1BFB2378A" modified="2013-11-13" version="1">MEIERKTVVQIAVSVAVVAVFFVGLIGLSSVYGSEVSYENEPLSGTVDNGELGESVDGAVSFQGDLDGKFTETTGGIEVAVNGSVDEPPTDGRLNSAFTATIDDTIANGTISGTLNGSASNGTFEGTFEGTITASGHDTEVTADGGLALVGLIVVFIILMPIAGYLIERSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX89</accession>
    <name>U1MX89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00906</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88760.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88760">
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        <property type="gene ID" value="J07HX5_00906"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194987_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="6203" checksum="5B02A6F3E22E4500" modified="2013-11-13" version="1">MLSRLGIAGALGLAVVLGGIGVIAVESPVVASGIGLVVIGAALVVYSLVQNVLGAFGMISGAGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXD2</accession>
    <name>U1MXD2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein conserved in bacteria (DUF2237)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00799</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88653">
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        <property type="gene ID" value="J07HX5_00799"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018714">
        <property type="entry name" value="DUF2237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466">
        <property type="entry name" value="PTHR37466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09996">
        <property type="entry name" value="DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9059" checksum="4F021106629AE792" modified="2013-11-13" version="1" fragment="single">MTDELNILGTELVPCGTDPATGYLRDGCCHHLPSDPGRHELCAAVTDEFLEYSRRQGNDLITPRPAVDFPGLEAGDRWCLCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXH8</accession>
    <name>U1MXH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00854</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88708">
        <property type="protein sequence ID" value="ERG88708"/>
        <property type="gene ID" value="J07HX5_00854"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087503_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="187" mass="19945" checksum="8853C8B6E8BD2297" modified="2013-11-13" version="1">MPSLEKTYEQHRSKNDRPRHVAAGVMLVGLGALAVAAAIVLVGVSQATGAKRWAGVVAGLGVPAMLFGLVVALPASRRARAGVGVGTALSAVGVGLFWRVYPGRWTRTADPFAFETLGVYAAGCAVALWFVFAALASFRRRNDPQGTVRVELVREGERRTVAVSRDRYRELVSDGGDPTAILRELED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXV0</accession>
    <name>U1MXV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01120</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88970">
        <property type="protein sequence ID" value="ERG88970"/>
        <property type="gene ID" value="J07HX5_01120"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1880983_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="13671" checksum="BB12275D94F123C1" modified="2013-11-13" version="1">MLWREELTAEIGAGDAGESAAHSIGGAASTRRGNLAPEQSASSVVSGSKATSETAQTVCSRAGHEQEFSGGVGTDRGAATGMSVQLAGRRTRVLGWPQQRVQLDSVAGQRATRGGCAGMRRTVRDRAGTGAGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXY1</accession>
    <name>U1MXY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbamoylphosphate synthase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01165</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89015">
        <property type="protein sequence ID" value="ERG89015"/>
        <property type="gene ID" value="J07HX5_01165"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_381094_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="186"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="727" mass="77511" checksum="F303B659568F6BBC" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXZ7</accession>
    <name>U1MXZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01019</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88873">
        <property type="protein sequence ID" value="ERG88873"/>
        <property type="gene ID" value="J07HX5_01019"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="324" mass="34642" checksum="C4D69EF6652CCFD1" modified="2013-11-13" version="1">MSTTILALAEHRNGKLREVSFETLTAGRQLANETDGELHVGVISGDVDRFGEQLAREGVDAVHTVDHGKMFNHDIYRQATTALIDELAPSYVLAPESINGFDYLPAVAEDQSMPLVTDAIDFTVGPDGLTVTRTFYADKVEGTVSVEAERAVVTIRTGEWPTTDAEADDPSRVPVNSFDPDIDTAAVQSTVKGLEQIESSGVDITEADVVVSVGRGIQEKENLEIVYELADELGAPVAASRPIIESGWLPADRQIGRTGKFVAPDVYIAVGISGAVQHTTGIKGSETIVAINNDPSAPIFDVADYGVVDDLFDVVPALTQRLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYA6</accession>
    <name>U1MYA6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01308</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89155">
        <property type="protein sequence ID" value="ERG89155"/>
        <property type="gene ID" value="J07HX5_01308"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="26"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="373" mass="39529" checksum="3E9B1965D6434068" modified="2013-11-13" version="1">MTEFAHRVEQMSISGIREVFEAAGEDAINLGIGQPDFPTPEHARQAAVEAIESGDADAYTSNRGTPALREAIAEKHARDGGLTVDPEQIIATAGGSEALHLAIEAHVDPGDEVLIPDPGFVSYEALTQLAGGHPTPVKLRTDLTLDPAAVEAAITDDTAMFVVNSPANPTGAVQSPADMRAFARIADEHDVVCLSDEVYERMLFAGEHRSPAAFATTDNVIVVNACSKSYSMTGWRLGWVTAAEDRIERMLRVHQYIQACASAPAQYAAEAALTGPQAPVTEMRETFAQRRDIVIDGLTDMGLSCPRPEGAFYAMPAVPDGWVDEVLDRGVVVVPGAAFGAGGAGHARLSYATDTEMIKTALETMADVTAAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYB2</accession>
    <name>U1MYB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01158</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89008">
        <property type="protein sequence ID" value="ERG89008"/>
        <property type="gene ID" value="J07HX5_01158"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010057_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="100"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="626" mass="67099" checksum="173DC89041F86755" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYD6</accession>
    <name>U1MYD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01184</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89033">
        <property type="protein sequence ID" value="ERG89033"/>
        <property type="gene ID" value="J07HX5_01184"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2406229_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10019" checksum="D87C532493E1B4EE" modified="2013-11-13" version="1">MLNVLTHNRVTITRVRDGNKKNVVLGTVRTTLDCRLVPGQTPADVIDELATVIGQSPSGEVLRFDPGPPNADIGLFDHLTATYSAMACQCRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYE2</accession>
    <name>U1MYE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01344</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89190">
        <property type="protein sequence ID" value="ERG89190"/>
        <property type="gene ID" value="J07HX5_01344"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="232" mass="23697" checksum="2BDB33900718E765" modified="2013-11-13" version="1">MIQSHADGVVRVLTLDRPSTRNALTREGLEQLEACLAAATEPVVYLRGAGTAFCAGADLAVVNSLDRASAVAFAELGQRVAAALAEYSGAVVAGIDGPARGGGLELALACDLRVATPAATFAEPGVALGLFGAWGGTGRLPRIVGLGNAMDLSLSGRVIDAATARRMGLVSQVCERPRAIADEVATAEPGALRAVARLLREPRGREPLERAEAAAFGECIARSDGPIGESRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYL7</accession>
    <name>U1MYL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone, small heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01275</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89123">
        <property type="protein sequence ID" value="ERG89123"/>
        <property type="gene ID" value="J07HX5_01275"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_15_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="20"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="13910" checksum="93C27EA468203F63" modified="2013-11-13" version="1">MALPQTTPNSWVQGLDFPSQLFETGGTDYELYEQDDEFVLSVELPGFDPSEITVAWDDGVLNIAADSEDPTRNQRRTHHQRFRFPKNVDDDGISAEYRNGILELRLPVETEAVATGREIPIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYT1</accession>
    <name>U1MYT1_9EURY</name>
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        <recommendedName>
            <fullName evidence="3">DUF5658 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89330">
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        <property type="gene ID" value="J07HX5_01488"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1072012_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043717">
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    </dbReference>
    <dbReference type="Pfam" id="PF18902">
        <property type="entry name" value="DUF5658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5658" evidence="3">
        <location>
            <begin position="173"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="259" mass="27656" checksum="E79A0D5399729BB5" modified="2013-11-13" version="1">MTDRGSEESRRTAPPQADVRAAVNEYLSQENEREETARDRRERTTQTDPASRDRDGGSGSRTTDESSVRAIVDEYLSDDANTEADRTQPARAESSSRERDRSQAGRRSVNTPAGTTAAVAGSGAGATGADGQESPSSGRSFDFEGINDIREMQGALLPIDIGWLFAALLYGGLDMFSTVLVLNNGGSELNPIYSLLGESLGAFVIWKTLVVFALFVVFYPDDPTGPEATDWVIPAITGVAGLFLTVNNILVLTTGSGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYV1</accession>
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        </submittedName>
    </protein>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8344" checksum="6E06A007499EEC0A" modified="2013-11-13" version="1">MANVNPLNGMMYGFRLMGYLITVLGVGVVLSLIGFSLVDGGSLISGGVVFLIGILAVFAGQAGVLYKVIADGFEKGMSAANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ48</accession>
    <name>U1MZ48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89455">
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        <property type="gene ID" value="J07HX5_01614"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9189" checksum="19D5BDB13CDCD9EF" modified="2013-11-13" version="1">MLTIDLEEFTFELADGAIKHVGASTTNASVTLYDVQTIERQPFGDDRVKLVFADDEGNKLAVSLAATQLDRIRAIASEESDAGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZH8</accession>
    <name>U1MZH8_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01607</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89448">
        <property type="protein sequence ID" value="ERG89448"/>
        <property type="gene ID" value="J07HX5_01607"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3093965_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="5628" checksum="ED75C16910E91D50" modified="2013-11-13" version="1">MLWRLCYWFWARSRTNATQSGTTAAPAGDERTGSSPKIGMTGDLRNHRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZR4</accession>
    <name>U1MZR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2">
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89548">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="11026" checksum="92C06892F85C69E5" modified="2013-11-13" version="1">MTEIELLDPETVIRGLTLLITTAVFLVTAITYYRTRVRRVLILALLAALLATNLLLEVGDEFLEEGIPYFELLTSLFALGIALLLLITVVRRFERPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZW8</accession>
    <name>U1MZW8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01927</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89755">
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        <property type="gene ID" value="J07HX5_01927"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2532514_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="84" mass="9333" checksum="DB55FB7B02CCB48A" modified="2013-11-13" version="1" fragment="single">HVKIFNCYQRMLSRVACRKFMQEITPLALDLLVTLCNCLPLVPPISSRQAVSPLLQEATQGATRPSNAVGRGYTAVITRNNNVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N012</accession>
    <name>U1N012_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01967</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89795">
        <property type="protein sequence ID" value="ERG89795"/>
        <property type="gene ID" value="J07HX5_01967"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_872891_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="320" mass="34646" checksum="33DB915408E7607A" modified="2013-11-13" version="1" fragment="single">MDNTTSDTDESDCTQSDNAVTTGFPRSSRRSLVKSIAAGAAVIGLPTGVTASAEVVSHAGMQDGTPVTPQQRVFDPIWYSPEQDYWKGVTRTEPSGKEYEGAALLRGTLTLNEIYSGNDGNMFSFNLFSFGIWASEGIPESSLENETGPVEMMHSNHQMKISCDDYDYDVREITTNYPRIGAELGRTNSSVNQDLFKELPEREDDWTSGEKDLKTADTSLPDGQESLMLGGASVATGVAAGIPTLGIGTAAFLTGTSVVFGLSGMIASMDDQGEEETQTDDEWSYRAKETTGGIISFRKDISVFSHNLIMDIPVKHDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N027</accession>
    <name>U1N027_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01839</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89668">
        <property type="protein sequence ID" value="ERG89668"/>
        <property type="gene ID" value="J07HX5_01839"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092340_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="165" mass="18245" checksum="916E92E59EC033A6" modified="2013-11-13" version="1">MTEIHATQRVAVLADSQNLYHSAQTMYTQNIDYAAMLNKTVAGRELTRAIAYVIRADSTDEESFFEALVDIGFETRIKPIQTFADGSKKANWDVGMSLDAVTLANHVDTIVLCTGDGDFVRLARHLHHEGVRVEVVCFGGSTADRLVEAADQFTDMSADTDRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1N040</accession>
    <name>U1N040_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor Spt5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spt5</name>
        <name evidence="6" type="ORF">J07HX5_01992</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Spt5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89820">
        <property type="protein sequence ID" value="ERG89820"/>
        <property type="gene ID" value="J07HX5_01992"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113589_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00950">
        <property type="entry name" value="Spt5_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011590">
        <property type="entry name" value="Spt5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00405">
        <property type="entry name" value="KOW_elon_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15820" checksum="BBDC36065B3A5401" modified="2013-11-13" version="1">MGIYAVKTTASQEETVADMIVNREEPKVHAALAPDSVTSYVMVEADDAAVFERILDEIPHARGVVEGQTSMAEVEHFLSPTPDVEGIAEGDIVELIAGPFKGEKAQVQRIDESKDQVTVELYEATVPIPVTVRGDQIRVLDSDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0E7</accession>
    <name>U1N0E7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mn2+-dependent serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02088</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89915">
        <property type="protein sequence ID" value="ERG89915"/>
        <property type="gene ID" value="J07HX5_02088"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1052133_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="265" mass="28951" checksum="FC200BC4B46F2110" modified="2013-11-13" version="1">MPFRELLRGHPPDETVTAIAEETARHQGMTFGSVEVLNVDNWLSLPLVVNNAFFVKVLSQRNALVQRLLTAGRNLGAASTGTGRFFRAFDTPAEMATHEFEATTEMIAAGVNAPEPLETFEHDDHGVVVFEYIPQFETLKTLTPTAVERLAPQLFAMLSCLHDAGLAHGDLRAENVLVVGEELYFIDATRVDAGAAEDARAYDLACALAALEPHVGAATAVDAAAASYTEETLLPARRYLEFVNVRPDHDFDVAELRRTLDTRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0G5</accession>
    <name>U1N0G5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01985</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89813">
        <property type="protein sequence ID" value="ERG89813"/>
        <property type="gene ID" value="J07HX5_01985"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3210632_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="44" mass="4879" checksum="34CB4314C49F28A0" modified="2013-11-13" version="1">MGVLAPNTAVKTIPLTSLAAVVLIIHSLYWIPGDERRMIYHVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0K1</accession>
    <name>U1N0K1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit Rpo12</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit P</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpo12</name>
        <name evidence="8" type="synonym">rpoP</name>
        <name evidence="9" type="ORF">J07HX5_02153</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89980">
        <property type="protein sequence ID" value="ERG89980"/>
        <property type="gene ID" value="J07HX5_02153"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179456_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00615">
        <property type="entry name" value="RNApol_arch_Rpo12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023464">
        <property type="entry name" value="Rpo12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="DNA_RNApol_7kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="44" mass="5151" checksum="C60449CABA6ACD2C" modified="2013-11-13" version="1">MSYKCSRCKRDVTLDEYGGVRCPYCGHRVLLKERSRDIKSVNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0V5</accession>
    <name>U1N0V5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase, PilT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02121</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89948">
        <property type="protein sequence ID" value="ERG89948"/>
        <property type="gene ID" value="J07HX5_02121"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1258403_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KH" evidence="2">
        <location>
            <begin position="101"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="244" mass="26267" checksum="DC203B22B7A548D5" modified="2013-11-13" version="1" fragment="single">DTVVYVDAGEIDVVYNVTTEVKVPEGLMEEDLARPVIVISDFETGRAEYEIYTFNRQVVTVPIGDEEQGGRESGVDRIAKDEIEREIRSIARGHVEVELHDSNTAVVWVEENDISTVIGKGGSRISDVEDRLGISIDVRTLADRTSTNGRGSQTGQTQTQAQTQPSGSTRTGGIAVAPEITDRHVVIPIEGHAGDTVEVRADSEYLFTATVSRGGEVQVSRGSAIAEELEGAIDNGRTVTVTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0W3</accession>
    <name>U1N0W3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02131</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89958">
        <property type="protein sequence ID" value="ERG89958"/>
        <property type="gene ID" value="J07HX5_02131"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082635_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006438">
        <property type="entry name" value="HAD-SF_TIGR01548"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01548">
        <property type="entry name" value="HAD-SF-IA-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="30500" checksum="2B1E68F2E48976C9" modified="2013-11-13" version="1">MQLEGLVLDIDGVVVDVSDSYRRAIVESVEHVYGATIDRAAVQQFKAAGGFNNDWELTSAAAMYVLARRHGDAAIGDVDAFTDAVATAGGGLDGARAVVCETLPCGASERVLAAWDHDRLRDTFQALYLGTELYRTLEPGAGPPPVETAGYIHDEPVVLTQATTAALADRPLGVFTGRPAAEAEIALDRTGLAVPPARRVTMDDPEPGKPAPDGLCRLADQLGVDRVGFVGDTRDDVRTAVRADAADDREYYGIGVLTGGLEGARGRRLFEDAGASAVVASVNELPALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P321</accession>
    <name>U1P321_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00008</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87867">
        <property type="protein sequence ID" value="ERG87867"/>
        <property type="gene ID" value="J07HX5_00008"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2103405_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="12452" checksum="B4832D1E9669DC9F" modified="2013-11-13" version="1">MPAWMELGQDKLEATAKPTGDELPGTDYNVYRLRKTDRWEEAILVNEAAETVFVPETIGSVPSFRAAGNRLGVHPAIEEPPDRLAEFDPTRVLVGHGEGVHENGSAALDAAITAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3J8</accession>
    <name>U1P3J8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00219</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88077">
        <property type="protein sequence ID" value="ERG88077"/>
        <property type="gene ID" value="J07HX5_00219"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1381360_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="197" mass="21962" checksum="D4A5199E6A6C26DE" modified="2013-11-13" version="1">MLTHELNRTHLGQGMDIVWHNQRAVTVGEQHYYEMCACKTGCLARIVARLAAIVTNQPDCVARALARYAEDMSIAFQISDDILDIENTLDQAGAFGKTAGNDIYEGKKTLMTIYTAARAPPEAVARLEEILWADEPTDEEVLEAIDIMRAAGAVECARDRAQELSASAREHLNKIDLKPEPDQTLREFSRFVVQRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3K9</accession>
    <name>U1P3K9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00229</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88087">
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        <property type="gene ID" value="J07HX5_00229"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037263_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
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        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="PTHR32419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="166"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="38025" checksum="CA6D2A2080522FB7" modified="2013-11-13" version="1">MNMLVDGEWRTDAYQTTNEDGEFDRQSTTFRNEIQDDPDAKFPAESGRYHLYVSYACPWAHRTLLVRALKGLEEAISVSVVDPFRGEGGWQFTPEKAGCTVDHVSDSDYLREQYQTADPTATCRVTVPVLWDTKQETIVNNESSEIIRMLDTEMNRFATRDVQLYPEDQRSEIDRITNAIYEPINNGVYRAGFAKSQAAYDEAVDELFEALDHWNEVLADQRYLAGDQLTIADICLFTTLVRFDEVYHTHFMCNKQYIHQYDNLWPYLRDLYQTPGVAKTVDMSHIKEHYYTTHPDVTPTRIIAAGPDPDFTADHDRDQLAGEPPAPLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Z4</accession>
    <name>U1P3Z4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00375</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88232">
        <property type="protein sequence ID" value="ERG88232"/>
        <property type="gene ID" value="J07HX5_00375"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_890272_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="312" mass="32615" checksum="96C6F7D139234A61" modified="2013-11-13" version="1">MIAARLRQALERLKGIFGSSEPTNKLEPANNQPRPPAQVAGCSVGGKKNERNEDAWSARTPTEETLVIAVGDGLGSKTHAHEGSAAATTAAAAELAEAEALTDDGDATSDRLAAPMEAAFAAARTAVEQRASTLGAPVDECATTLLAVASDRSETVAAAVGDGGIVGDDDGVYFPVIDREAGEYANVTTPLTAAGWRDAYRFGYTDRAEAVAVFTDGLSNFTWERAGDATPETAFFEQVFPPVHSARRAAEVEPALCAFLGDEHFRQHSRDDKTLVVGVPVPRPSTPTATVSAGTTDPAPRSTSRSTGETDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P492</accession>
    <name>U1P492_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00466</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88322">
        <property type="protein sequence ID" value="ERG88322"/>
        <property type="gene ID" value="J07HX5_00466"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3072921_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="53" mass="5537" checksum="7B325601E7494DFD" modified="2013-11-13" version="1" fragment="single">MADPWEPGHDSISQVGLLGDESGTIKFVAFDTSDLPELAAEAGYALGNVVTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5B2</accession>
    <name>U1P5B2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00878</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88732">
        <property type="protein sequence ID" value="ERG88732"/>
        <property type="gene ID" value="J07HX5_00878"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="5">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="255"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="534" mass="56354" checksum="209444AA24B33AB2" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1P606</accession>
    <name>U1P606_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Archaeal thermosome subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01127</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88977">
        <property type="protein sequence ID" value="ERG88977"/>
        <property type="gene ID" value="J07HX5_01127"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03343">
        <property type="entry name" value="cpn60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012714">
        <property type="entry name" value="Thermosome_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="PTHR11353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02339">
        <property type="entry name" value="thermosome_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="595" mass="61741" checksum="0039EAACA6A9622F" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P642</accession>
    <name>U1P642_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Gas vesicle structural protein</fullName>
            <shortName evidence="4">GVP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gvpA</name>
        <name evidence="6" type="ORF">J07HX5_01167</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Vacuole</location>
            <location evidence="4">Gas vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the gas vesicle protein type A family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89017">
        <property type="protein sequence ID" value="ERG89017"/>
        <property type="gene ID" value="J07HX5_01167"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169045_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033172">
        <property type="term" value="C:gas vesicle shell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00576">
        <property type="entry name" value="Gas_vesicle_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000638">
        <property type="entry name" value="Gas-vesicle_GvpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018493">
        <property type="entry name" value="Gas-vesicle_GvpA_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00741">
        <property type="entry name" value="Gas_vesicle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00234">
        <property type="entry name" value="GAS_VESICLE_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00669">
        <property type="entry name" value="GAS_VESICLE_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8284" checksum="51D190EFB947621C" modified="2013-11-13" version="1">MAQPDSSSLAEVLDRVLDKGVVVDTFARISLVGIEILTVEARVVVASVDTFLHYAEEIAKIEQAEMTAGTEAAPVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P667</accession>
    <name>U1P667_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01198</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89047">
        <property type="protein sequence ID" value="ERG89047"/>
        <property type="gene ID" value="J07HX5_01198"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1312416_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="210" mass="23216" checksum="5386A6DF3B265C8C" modified="2013-11-13" version="1" fragment="single">MTVTDDTPSDQSQSDTASAADSESKAESKAPTAPADETAGADAFYDALERLDTPVVTAAQYARVREVDQAAALDELEAVTAAGDAERCSVPGPAVWYPVEWGQLVDRERLVVFPDRREIIADQPAQFTRAQLSQFARLTTTSGDGAARYKVRSQDIWQSPHDSLEELLRTVRQTLPGRYPSVEEWIEGQYSRANQFRLYTHDDDYTVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6C2</accession>
    <name>U1P6C2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase II large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">J07HX5_01264</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal DNA polymerase II family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89112">
        <property type="protein sequence ID" value="ERG89112"/>
        <property type="gene ID" value="J07HX5_01264"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558419_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004475">
        <property type="entry name" value="PolC_DP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016033">
        <property type="entry name" value="PolC_DP2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42210">
        <property type="entry name" value="PTHR42210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03833">
        <property type="entry name" value="PolC_DP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolC_DP2" evidence="13">
        <location>
            <begin position="13"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="232"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="381"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="424"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="489" mass="51494" checksum="62ED1636820B4EC4" modified="2013-11-13" version="1" fragment="single">MARRRTXXXXXXXVRELEGDRSREEAALALTEDFVAGDVGDYETAAGKIEGAVRTAVALLTEGVVAAPIEGIDRVEIRENDGGEFVSVEYAGPIRSAGGTAQALSVLVADYARSLLGIGAYQAREPEVGRYAEEVALYDDETGLQYAPNEAEARFIAEHLPIMLDGEPTSDGDVEGYRDLERVSTNAARGGMCLVFGEGIALKAPKIQRYTRELSAVAWPWLQTLIDGDYAAAHSTGSDNDNSSDNSASNSNADAETDTDADPGADDRTHADSAPETAPGPDAAAPADDDDTAAQSPPSSAPRAEPTDKFLTDLIAGRPVFSHPSEPGGFRLRYGRARNHGHATAGVSPATMHLVDDFLAPGTQLKTERPGKAAGAVRLIRSKARPSGWRPARSAGSTTPRRRSSCETASSACLISASILSTTASSSRTTTTSPRRATPSSGGVKSSPPPARRSERCETPQKSTSPTRPRSGRSPGPTPTCRSTRPTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6I4</accession>
    <name>U1P6I4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01335</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89182">
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        <property type="gene ID" value="J07HX5_01335"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="57"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="15598" checksum="E54793B9907E4649" modified="2013-11-13" version="1">MDELPDTGTEGVRTFTVRSAHTTTVFGEQTNPPGRAAATDADPSETRKVVGSAQILARFEFLARESVRGQLPPGTGLVGEQGTVTHRRPASVGTELRVETTLTTATDATLVFDGRATNPADAVVGKGTVRTRVVDRERFCGQVDDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6X4</accession>
    <name>U1P6X4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3887 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01480</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89322.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89322">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1438075_0_0_2"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3887" evidence="2">
        <location>
            <begin position="59"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="188" mass="20254" checksum="E90D5EDAB2694B51" modified="2013-11-13" version="1">MAVLAAGCSGSNDTTSASPPPTDQHNPDENATPADTDPDTEPATDSDSDPASETLETQAREFIELQMSGLFVDAYDGLTMSFAAEFSIDEIRQGWQQMVTTSGRFGSIAAVNYTETTDGLARVTVETTFNDVRNTFTIFIDPSSGIEGYHITDQSEYDWTPPPSFPPVSSPTLLRLLTGTPDRRCQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P735</accession>
    <name>U1P735_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_00072</name>
    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87931">
        <property type="protein sequence ID" value="ERG87931"/>
        <property type="gene ID" value="J07HX5_00072"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3353829_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="36" mass="3625" checksum="0A415E0BC2DD2003" modified="2013-11-13" version="1">MTAAPGMPVVDVGLLVPPALVSLDELYLEGETAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7D7</accession>
    <name>U1P7D7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative N6-adenine-specific DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01632</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89472">
        <property type="protein sequence ID" value="ERG89472"/>
        <property type="gene ID" value="J07HX5_01632"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032119_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="43"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="361" mass="39176" checksum="B36F5F72D911763B" modified="2013-11-13" version="1">MELLATTNRGLETVAIAEIKRLTGAEATVHHPGMVRFSAGVSAVYRLNARARSLHRVLIELTRGAVGDLTEIYQATRESDVGWVLPSDQPFAVRAQRRGDQSFGSPEVASTVGQAIVDSYAEPPPVELDEPAVVVRALVRGETLVLAVDTTGQSLHRRWYRAVEHDAALRPTVAHAMVCLAKGGDDSNLAGRLLDPMCGCGTIPIEAALATNDIAPSTEYEPALTSLRPFAATRYQTHVHDQSQQRAVTPEQIVGRDREREWVQGARENAAAAGVTGAVSFAVGDATVQPVTADLIVVDLPFGVRTDSRPDQLYEPFFDALGDDWDRLVVLTTREELVPYDPTETLELRRGRLNASVLVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7F8</accession>
    <name>U1P7F8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Non-histone chromosomal protein MC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01653</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Protects DNA against thermal denaturation and modulates transcription.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89492">
        <property type="protein sequence ID" value="ERG89492"/>
        <property type="gene ID" value="J07HX5_01653"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154331_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008674">
        <property type="entry name" value="MC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036620">
        <property type="entry name" value="MC1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05854">
        <property type="entry name" value="MC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102875">
        <property type="entry name" value="SSF102875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
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        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05854"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="12712" checksum="6BCD22486A592700" modified="2013-11-13" version="1">MDGVHISIGVVIPMADDKRNFALRDGSEETSVFSGGTPRQAALKAARRLDPATSESRGQSNATELRLREKGTHKVHVYLGWAWEESAPDDKPDWMPDEITKGNVSKEGVEHLEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7I5</accession>
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        </submittedName>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG88101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88101">
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        <property type="gene ID" value="J07HX5_00243"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="12296" checksum="0E68611B15BB408F" modified="2013-11-13" version="1">MTQTQALSKALVFPLDVQSGNESLLHDARLECRRVFNEVLRLNYDGSKWNEIENMIEQNADLVQNTAQCVIDKAFDALNNHYNNDDWGRPWYKHKTFQMPMGYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7I7</accession>
    <name>U1P7I7_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Ribosomal protein S6E (S10)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01687</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ERG89522.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89522">
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    </dbReference>
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    </dbReference>
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        <property type="term" value="C:ribosome"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
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            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="7803" checksum="A1721A2126B6A90A" modified="2013-11-13" version="1" fragment="single">GSDDAGRPMRADVSGSNLRSVLLTGGTGYDPSRDGERRRVTVRGSEVSDATRQINAKITGRGDEPVEELLESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7K8</accession>
    <name>U1P7K8_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Succinylglutamate desuccinylase</fullName>
        </submittedName>
    </protein>
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    </gene>
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    <reference evidence="3" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="168"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="918" mass="97791" checksum="CB0774998BC6884C" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7S2</accession>
    <name>U1P7S2_9EURY</name>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="ERG89607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7794" checksum="3AFB7D92BA494F1D" modified="2013-11-13" version="1">MGRLFQQAYTDKQLTHKGSVIPANAQSFITEWIPFCCMSLGSNTTAGTTARRNRNTSPTTTLKQRPTVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Y2</accession>
    <name>U1P7Y2_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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    <reference evidence="2" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="138" mass="15824" checksum="9816922383A02D68" modified="2013-11-13" version="1">MITTVKERLQSDEIRLFCLHCREYERTRTVGSVSDQPGCPECGSTRIAALNPWDEETPPAVRSGDKDDDQQKRTERAYRAASLVQSHGKQAVIALAARGVGPHNAARIINKLREDEDDFYRDILSREREYARTRSFWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Z1</accession>
    <name>U1P7Z1_9EURY</name>
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        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01854</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89682"/>
        <property type="gene ID" value="J07HX5_01854"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="27867" checksum="51034F3EBA04F028" modified="2013-11-13" version="1">MSDTISTADNAIETDGLTKQYGTVTAVSELKLSIGRGEVYGFLGPNGAGKTTTMRLLTTLTEPTAGTGIVAGVPVTNRAALTERIGYLPAEPPVFDELTGREYLRYIARLRELDDETATGQIEQYLDRFELSADNRRIEGYSTGMQKKLGVIGAVLHDPDVLFLDEPTSGLDPRAARTMRETIAELAEQEMTVFLSTHVLPIADELADTIGVIHDGKLVAEGPPTELTARSADGTDLESVFLELTREDDTSREANYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8H3</accession>
    <name>U1P8H3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein conserved in archaea</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02019</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89847">
        <property type="protein sequence ID" value="ERG89847"/>
        <property type="gene ID" value="J07HX5_02019"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071219_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="317" mass="33287" checksum="5C8C5283866952CE" modified="2013-11-13" version="1">MTADQTDPRPEGDFETVEINIGADNVSGERFDLVTDLRLYHTGVSEDVTVELRAVGLNSGLTEASETVAVGSVERTGELAVNETLNVERAGGYQLEAVVFQGSDRGTAESKTVRGTGALTPGYPDSPVAFLQFPVYDLPVIDYQIVSKNNNIATLDIETYLTNSGDGTAEDLTLRLKARQVESGVVAAEQSIPVGAIGPEETARPGDELTVPSEYNYYLDATLWNGNQIVDTTRAGASLDPTERVQANATQREVAFELGDFTDDGGESSAPPGERTGAPADGDGGGPGFGVGVAIIALAVGIGFRAQARVNTGKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8H8</accession>
    <name>U1P8H8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00571</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88426">
        <property type="protein sequence ID" value="ERG88426"/>
        <property type="gene ID" value="J07HX5_00571"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2820649_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="6914" checksum="9CE3C67DB8029EEF" modified="2013-11-13" version="1">MCRQRVFRTLASVGVSGAALPHLSRDVVAERVANCGSKLLTHKDSPDELAEEDGRSAPSVLAGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8K6</accession>
    <name>U1P8K6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00606</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88461">
        <property type="protein sequence ID" value="ERG88461"/>
        <property type="gene ID" value="J07HX5_00606"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048695_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="397" mass="41213" checksum="9DA0E79B0B4F1EC9" modified="2013-11-13" version="1" fragment="single">MCPRLAPLPALSIGFTVCCLGVLVVFVGVGGVLAGTAATQSSVSNETITTEIQLQPNGDANWDVSVELELTTDNEVTAFRETATRFKTGGDGDSNEGLDLGLSAFRAASDRVSDRTGREMSITGVDRTSDLVRNASAGTIGAGRLTLSFSWTNFATVDGNRLVVNDVLTTEQGPWLERLGANERLLMRGPPDYLPEDAGGAANITDGTLCWKGPITFDERSLAATFDRLVGPSEPPGQPGDNEPSPGDGGLSVVLLGGGVAAAVATAVLGYLVGRRFDISLPREPGSETAAENEAANSGPAQGADSETAAGTRDRGSIDGTAGADTSASGGENDNRTGTKVETGEPAAPELLSDEERVERLLRANGGRMKQAVIVEETGWSNAKVSQLLSTMKENDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8S1</accession>
    <name>U1P8S1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02110</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89937">
        <property type="protein sequence ID" value="ERG89937"/>
        <property type="gene ID" value="J07HX5_02110"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176775_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="98" mass="11435" checksum="A1C2CC06A628A4AC" modified="2013-11-13" version="1">MQLAARIRAYREVVAEWLRGLYHGMISHPAYEKIEKAAEDSEDGFLLACFPDAFGVPSPVSYYTAELLPYLGEEFQQWERRMWDRGSALERKGSQYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Y4</accession>
    <name>U1P8Y4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00742</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88596">
        <property type="protein sequence ID" value="ERG88596"/>
        <property type="gene ID" value="J07HX5_00742"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954577_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="13972" checksum="33BBCA151AB6538F" modified="2013-11-13" version="1">MSRASTTILRRRKCADTVDYRKQHVDTNGSAIAQQVIWKKESAWQSFFAVLAVTKPTPTCARLAHSSNNRLANQTSGRWHSLCASSGTTTTGRSYHTPPKGPVPTRSAYSGIPAQAKLPLLVGNEHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9D1</accession>
    <name>U1P9D1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00892</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88746">
        <property type="protein sequence ID" value="ERG88746"/>
        <property type="gene ID" value="J07HX5_00892"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1167941_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="104"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="238" mass="26187" checksum="6B71BA432BE47C01" modified="2013-11-13" version="1" fragment="single">MSLFSVLARRFAAGLVTVWATLSALFALFYFTDDWNLDRILASLRRSPGGQEQQFREQYLAGRGRPDGGFVTQYGEFLVDMFSLQWQESYATGESVLSLTISAALRTGAYVLPATVLAIVLALSVGLYAALRPRTIREQVVRAAVYLGLGIPSFWIGVFLLDWSERVAFRFSGPSDVISASALPFLYEWVAPVVLVTMTLVAAITSYARSQSLQYVNKDAARLVRAKGGGTIDVTRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9W1</accession>
    <name>U1P9W1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01022</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88876">
        <property type="protein sequence ID" value="ERG88876"/>
        <property type="gene ID" value="J07HX5_01022"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_16_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="183"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="328" mass="37567" checksum="EDA691CCDA12BCEB" modified="2013-11-13" version="1" fragment="single">MAKQVVTRTYTASIRNQQQVQDDLDSLGFAASKLWNVGRWVCDRVWSEIGHIPSHNELTTYLKSHERYDDLHSQSSQRVLQELAEAFTGWYGKRRNGDTKANPPGYRKHGDDHPRSTVIFKAAGFKLDTKYGRVRLSKGANLKEYWSDFTLCKYQIRPDVDLSTVENIRQVRAVWTGDEWELHFVCKVEIEVAESPDKKTVGVDLGINNFAALAFEDGHSELYPLNCLKQDDYYFSKRLAQCDDSDSDQATRLNQKKSARRTHYFHTLSKHIVGRCVDKGVGAIVVGDLSGIREDEENGESKNWGKHGNLDLHSWAFDRFTDLLTYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA15</accession>
    <name>U1PA15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IMP dehydrogenase/GMP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01089</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88941">
        <property type="protein sequence ID" value="ERG88941"/>
        <property type="gene ID" value="J07HX5_01089"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1566066_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="170" mass="17501" checksum="01A5FA63183B48C2" modified="2013-11-13" version="1" fragment="single">SHCITREVTGVGVPQFTAVEECSAAADTHGVETIADGGIRTAGDAVTALLAGADAVMLGGFLAGCTESPAETVEIDGERYKQTRGMSTAAAAEARADKDAEIVADEGVETTVPHTGPVGPRLEEFVAGIRSGLSYVGAQDLTTARKRAEFIKITSASNRRNGSHGVARKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA69</accession>
    <name>U1PA69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gas vesicle protein GvpN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01151</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89001">
        <property type="protein sequence ID" value="ERG89001"/>
        <property type="gene ID" value="J07HX5_01151"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051123_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013462">
        <property type="entry name" value="Gas-vesicle_GvpN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02640">
        <property type="entry name" value="gas_vesic_GvpN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="4">
        <location>
            <begin position="90"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="352" mass="39528" checksum="A8034D5624F348CC" modified="2013-11-13" version="1">MSKDTTHNRKVRGSQIRSSRADKQQRRATDRAKKSVDRLEKQQTETDETASGLSDQFVPDDQTFVETAAVNRMITRTQRWLDAQYPVHCVGPTGCGKTALAMRVARRRDRPVVWINGDAGLTTNDLVGEYAETERVSERDKYIHNVIKSKEIVRDRWVDNPLTVAVREGATLVYNEFSRTKPAANNVLLSVFEEGVLELPGQRGESRYVDVHPEFRAILTSNSVEYAGVHTPQDALLDRLVSIHMEFYDRETEIEIVRAHTDDVTADYVVPMVQLFRELRDQLEITVGTRAAIMAVRGINATDELSRSMLIDICVDVLASKVSELGAVRELRSSVETAVAGLETAPIQSEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB24</accession>
    <name>U1PB24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01443</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89286">
        <property type="protein sequence ID" value="ERG89286"/>
        <property type="gene ID" value="J07HX5_01443"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53720"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="13"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="482" mass="50746" checksum="D78BDA4C87F3B9F9" modified="2013-11-13" version="1">MPETHHNYVGGEWTEASTGETFAVQNPADTDTVVARFQQSDETDAKAAVAAADAAAGEWAETPGPDRGAVLNSVAKRLERRQDALTKLLSREEGKTTDEARPEVQRAIDIFYYYAQKAREFGGTVRPAGGDRRRLYTVKEPMGVAGVITPWNYPIAIPAWKIAPALATGNTVLFKPAPQAPGVGREIVKAVAEAGVPDGVINLVTGPGESVGETFVTDERVDAVSFTGSSTVGNHVYNLATDAGKRAQTEMGGKNPVIVTESADVAEAVAIVGNGAFGVTGQACTAGSRAIVDSSIADAFLDGIVEHAESIEVGAGTDGADMGPQISQAELEGTMEYIAVGQEEATLLTGGSQPAGATGQSGHFVEPTVFANVTPEMRIAREEIFGPVLSVLTVDGFDEAVEIANHVPYGLSASVVTDSHEQVHEFIQQIESGVVKINEKTTGLELHVPFGGVKDSSSNTFREQGEAGLEFFTTTKTVYENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBK7</accession>
    <name>U1PBK7_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Putative nuclease/nucleic acid binding OB-fold tRNA/helicase-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01615</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="J07HX5_01615"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="485" mass="51553" checksum="A1B01FB68689C643" modified="2013-11-13" version="1" fragment="single">MSSCIICGASTDGRVCNLHEEDVGFVFHGTDPDQLQSNRYYRGTVDGYAEFGVFVNIGESVTGLLHRSEIDQRLESLPYDTGDELFVKVQNVRSNGNVDLGWSIRQEGSAFRGMLVDDPETGEELVEAPDPESETQSDRESGAESETDGGTAANVAGESTLSERTDSETADTGPESTSGVETSTESSGVSGDSDNNNNNDNDSDGDAAGSETDAGTIAAATTTELASVTITALADQIGDPVQFEAAIEDIRQTSGPTVFTMSDESGTVECAAFDGAGVRAYPDVETDDIVRVTGEPEQRRGSLQVEVEELTVLDGDAQAAFVERTEAALTDRAQPDRVEPIADDPAVAAVSDSLSSVTTELRRAVFEGRPIVVRHAATVDGYAASVAIERATLPLVREQHQDPDAEYHYFDRRPVEGAVYDMDDATRDVTRMLSDEAQHDEPIPLFVFVAAGGTTESRDGLDLLGVYDAPRVVVDAGAVPSAIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBV3</accession>
    <name>U1PBV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01727</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="47" mass="5048" checksum="6785B7CD284FA67F" modified="2013-11-13" version="1" fragment="single">MDLSAVRVLDLTQLLPGPYATQLLADMGAEVIKIERPDGGDPARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCC2</accession>
    <name>U1PCC2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PepSY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01913</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89741">
        <property type="protein sequence ID" value="ERG89741"/>
        <property type="gene ID" value="J07HX5_01913"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450975_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PepSY" evidence="2">
        <location>
            <begin position="244"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="606" mass="63797" checksum="2350DD7218895C4D" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCR4</accession>
    <name>U1PCR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02038</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89866">
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        <property type="gene ID" value="J07HX5_02038"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_204299_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="6358" checksum="8C28BF1C514CE991" modified="2013-11-13" version="1">MTTMETGLGGTVSIEVGAVIVAIVSSILLLAAVLAVGRDLVPSLVEVSIGGVVVGVAYYLGLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCS3</accession>
    <name>U1PCS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02053</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89881">
        <property type="protein sequence ID" value="ERG89881"/>
        <property type="gene ID" value="J07HX5_02053"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504835_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="8717" checksum="651E2DCB641CA89B" modified="2013-11-13" version="1">MGRLVTLSESALRPARCLAACWVRSGRLSDLGGVIVPAGAALLTVTVTGPGSSWASARAAGCSTDRAGSHDSLTDCAWSRRDQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCW5</accession>
    <name>U1PCW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_02104</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89931">
        <property type="protein sequence ID" value="ERG89931"/>
        <property type="gene ID" value="J07HX5_02104"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="279"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="41374" checksum="5E5ECCC4560D555E" modified="2013-11-13" version="1">MSSRYRRGSSSDRXXXXXXXYTSGTTGPAKGVRHEHRWIAGVAATQRYAVDLQPGDLYWSTGDLGWLTGAINTLGAWFWGTSLFSYEGEFAPDRWTELLASYPITVLFLMPTAYRMLRETAALDDVDLDLRHALSIGEPLSPGVIDWGRDTLGVTILDTYGQTETGNMIINNYPTMEPRPGSMGKPLPGIEAEIVDPETGEILPPGETGEIAQRGGYPCFFAGYWEAHEETADCFVDGPTGSWYLSGDLAYRDEDGYFWFEGRADDVILSSGYRIGPFEVETALNDHSKVAEAAVVPKPHPERGNIVKAYIVPSEAAAPSPELKASIKQQVKHELAAHEYPREIAFLEELPKTVTGKIRRTELRDRVVSSPATAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFJ0</accession>
    <name>U1MFJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00015</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87874">
        <property type="protein sequence ID" value="ERG87874"/>
        <property type="gene ID" value="J07HX5_00015"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_184177_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7268" checksum="AF01E96FBB598A1E" modified="2013-11-13" version="1">MATEQCDGCKKAVNIGGGIADIWTLDTGPTEGLTLELVDGTEHFLCYDCIDRLPDDHEVTATDVAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFN1</accession>
    <name>U1MFN1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Double-stranded beta-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00090</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87949">
        <property type="protein sequence ID" value="ERG87949"/>
        <property type="gene ID" value="J07HX5_00090"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108780_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="40"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="21742" checksum="D53D5EA32FA1D59E" modified="2013-11-13" version="1">MPASNAKTEQETLETSFGEQFRFETTAVDSDGELLRVETRLDPGVRRPLHTHPKQDETVVVQQGVLGLAIEDQEHTLEAGEKETVSAGTAHTFWNAGDQPVRVTTEHRPALRFEAFLRTMVRLDQADRLNEQGMPAHPLTGAAVLTEFSDEMRAEDVPGLVQRTVFPVLARLSGPLGYALPDHEQTQPNPSARERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFV0</accession>
    <name>U1MFV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00185</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88044">
        <property type="protein sequence ID" value="ERG88044"/>
        <property type="gene ID" value="J07HX5_00185"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1080186_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="281" mass="30232" checksum="DB3FED3274906DDA" modified="2013-11-13" version="1">MFGLPVVLCLDSVCQGQWSLCECCFSQLFMMLVAILYRVIVVATADFELYHDVVAELRARQLSFTTVDSNAALPPETTVLITGTDAKRLSVPDGVDTVSATPEAARSAVEEAVSMFRDDGRTIVGIDPGERPGVAVLVGDRIVATFQLPPDDVPAVVREETADASNPLVRVGDGARLIGARLIEELELPVELVDETGTTPYLGTGVRGVGDVLAAVNIARIEGDYIKAREIEPTDGELTRIKDRARKQSDTNRAIDATLAREVAVGNLTVEEALDQHRSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG10</accession>
    <name>U1MG10_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate dehydrogenase related dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00262</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88119">
        <property type="protein sequence ID" value="ERG88119"/>
        <property type="gene ID" value="J07HX5_00262"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2379287_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="94" mass="9737" checksum="7414A95AB36254DF" modified="2013-11-13" version="1">MIGPEAFAAMPDDAYFINTARAALIEDGALLAALETDEIRGAALDIYPEEPIAETDPLLAMDTVVIACAARKPTALAVGGSAFAPSGQPRRHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG54</accession>
    <name>U1MG54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00322</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88179">
        <property type="protein sequence ID" value="ERG88179"/>
        <property type="gene ID" value="J07HX5_00322"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2447548_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9493" checksum="987BB49A514FF371" modified="2013-11-13" version="1">MDRVEHVISGDRLPLGKAVPVTKLQVHRVVAEAYSFSRGKKAIGIFDLMYAIKTYFTGLEVVGETGSPSACPDIGSGERVSPTPSVEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGA9</accession>
    <name>U1MGA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00387</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88244">
        <property type="protein sequence ID" value="ERG88244"/>
        <property type="gene ID" value="J07HX5_00387"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048085_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="12"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="25112" checksum="7A353E209C3135B3" modified="2013-11-13" version="1">MVDFESLRVGFAFGAGTATFFAPCALPLLPGYMAFFLGHENDSQSQPVASRLQRAFVVSLFASVGFFLVFTVLFGMTLAFGSQVLGNVALLELVVGPLLVVFGVGMTLGRNWLPTAHVTLPKRRQGLPGYVAFGVVYAAAAAGCTGPLFIGIASLGVSAGPVATVGMLAAYAAGMSLLLGIVTVLTALGRDTLVTTLTGNTEVVTRAAGIALILAGVVQLYWFLFVFNGTIVLEELLAWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGD6</accession>
    <name>U1MGD6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chaperonin GroEL (HSP60 family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00417</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88274">
        <property type="protein sequence ID" value="ERG88274"/>
        <property type="gene ID" value="J07HX5_00417"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="PTHR11353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="237" mass="24956" checksum="8116E3EC3E6EB5CB" modified="2013-11-13" version="1">MSQSGQQRMGGQPLFILSEDTERTEGDDAQSSNISAGKAVSETVRTTLGPRGMDKMLVSDDGDVVITNDGATILDEMDIEHPAAQMLVEVAQTQEDEVGDGTTTASILAGELLSNAEDLLEDDVHPTTIVEGYYAGAEFAQEAIEEAVVTTDLSDDQMLYVAESSMTGKGTGDVAGPVLAETVVDAIDQVRTDDGVDRDSITIHTQSGASSSSTELXXXXXXXATMIVRIDDVIASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGH8</accession>
    <name>U1MGH8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00463</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88319">
        <property type="protein sequence ID" value="ERG88319"/>
        <property type="gene ID" value="J07HX5_00463"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165168_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="12548" checksum="AFF7EB9B13C273A5" modified="2013-11-13" version="1">MKLVDQTMKLVDQRLPLVLGSIGVLLGSIWLSLPVAFVVGAAVSGVVELITRGIPHPGATDDYWFLPWRETPPEYRMKEPTEVSQLREKYVEDEIDEKELEKQVEKQLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGR6</accession>
    <name>U1MGR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00554</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88409">
        <property type="protein sequence ID" value="ERG88409"/>
        <property type="gene ID" value="J07HX5_00554"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1252895_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="221" mass="24169" checksum="AE3707BF99B42845" modified="2013-11-13" version="1" fragment="single">MVTPHRVLYVGPDHQTAEEALDEHLSQSKIEAVPSPAMALKLLADQLDCLVVAHTPEFDGLSLLRTVRDRAHDLPVVLFPKRGDEALATQALRAGATDYVRRTDNQPYTLLASQLTDVASGADPDTALDPHPAETAVPYKMLFTHANDAVVMVRFADDVPTVETANQLFIEQFAPEADLSEIVGRDIDAVVTPPARRESARAITERVRDGELVTNTVTRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGS1</accession>
    <name>U1MGS1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00559</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88414">
        <property type="protein sequence ID" value="ERG88414"/>
        <property type="gene ID" value="J07HX5_00559"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1773249_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043814">
        <property type="entry name" value="DUF5796"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19109">
        <property type="entry name" value="DUF5796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15631" checksum="7B5DB96E129ACEFF" modified="2013-11-13" version="1">MEEPLALSPEPLSVDCDGAGITVTYADGRTVLYRGVPASVGSTHTTAPGTEVHLLVTDHETGRLVYIDERTTDRAVLEQSGVGRLRLDANESCPAFPGVQVTRAGPRLKFVVDPDTFEASAVFVFEQDQFGERSVELLAAETPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGU2</accession>
    <name>U1MGU2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="6">IMP dehydrogenase</shortName>
            <shortName evidence="6">IMPD</shortName>
            <shortName evidence="6">IMPDH</shortName>
            <ecNumber evidence="6 13">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">guaB</name>
        <name evidence="16" type="ORF">J07HX5_00594</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 13">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 13">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 12">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="6 13"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88449">
        <property type="protein sequence ID" value="ERG88449"/>
        <property type="gene ID" value="J07HX5_00594"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 13" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 13" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="6 13" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="102"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="164"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6 8">
        <location>
            <begin position="343"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6 8">
        <location>
            <begin position="366"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6 8">
        <location>
            <begin position="390"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="6 7">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="255"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 9">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 10">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ERG88449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="492" mass="52124" checksum="A6DCADE6AB344CB8" modified="2013-11-13" version="1">MATPSEPFSEKLRVPESLTFDDVLLRPKASTVEPDEADTATRVSTNVTLSIPVLSAAMDTVTESDLAVEMARQGGLGVLHRNMTVEAMAAEIEQVKRRDELIIRDVVTAAPDQTIRAVDQMMDEAGVSGAPVVDDDGRVLGIISGTDIRPYLEVGDHDAVREAMTDEVITAAEDVTPRAALELMYEHKIERVPIVDDENHLTGLITMAGILQRREYDQAARDRDGHLRVGAAVGPFETDRALAADDAGADILFVDTAHAHNQAVIDGARTIKSEVAADVVVGNIGTREAATELVEFADGIKVGIGPGSICTTRVVTGAGMPQVSAVAQVADVASQHDVPVIADGGIRYSGDAIKAIAAGADAVMLGSYFAGTDEAPGRVITMQGKKYKQYRGMGSVGAMQSGNDNRYLKDETDEELVPEGVEAATPYKGTLESELTQLIGGMQSGMGYVGAASIPAFKQRAEFVRVSSAGQQESHPHDVVITDEAPNYSPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGU6</accession>
    <name>U1MGU6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00599</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88454">
        <property type="protein sequence ID" value="ERG88454"/>
        <property type="gene ID" value="J07HX5_00599"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2985533_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6096" checksum="F0EA0B2B4AB9585A" modified="2013-11-13" version="1">MCRCSKPTLSSLRRVTVCEPTASEGTENKRGGSADHYGRLSFECACLQASASLETAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGY1</accession>
    <name>U1MGY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00655</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88509">
        <property type="protein sequence ID" value="ERG88509"/>
        <property type="gene ID" value="J07HX5_00655"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1017366_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="1">
        <location>
            <begin position="9"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="273" mass="28963" checksum="2B0F3CF03139CF02" modified="2013-11-13" version="1" fragment="single">GLLERGELEPGGTVIEPTAGNTGIGMALAATQLDLEAVFIVPEEFSVEKQTLMRALGAEVINTPTEAGMQRAIEYATELAAETDNAVVPEQFSNPMNPAAHVQSTAPEIYDALDGEVGAIVAGCGTAGTLMGLAQYALEREPATQIVAVEPEGSLYARTEDRDIDREEYTIEGIGTSDLASKQLYDPTMVDEVRQVSDRAAHTELKRLAAEEGQLVASSAAAASVAARDVATRIRDGDLSVPHETVATVFPDSSERYLSNGLYDSFEAWAGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH65</accession>
    <name>U1MH65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00780</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88634">
        <property type="protein sequence ID" value="ERG88634"/>
        <property type="gene ID" value="J07HX5_00780"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="449"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="533" mass="56731" checksum="A96220F85748FC69" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHA4</accession>
    <name>U1MHA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Subtilisin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00835</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88689">
        <property type="protein sequence ID" value="ERG88689"/>
        <property type="gene ID" value="J07HX5_00835"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_322782_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="210"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="897" mass="92945" checksum="497EA71C3C979324" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHD0</accession>
    <name>U1MHD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00865</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88719">
        <property type="protein sequence ID" value="ERG88719"/>
        <property type="gene ID" value="J07HX5_00865"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095571_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="169" mass="18306" checksum="B7EBF85F0E86E6BB" modified="2013-11-13" version="1">MGNKTDDLRELFQSVTGTDAVTDRQQTVGESGGDTAAQLATLIDRMREQYAFETNLSTGTYEEIVRLYHDGLTDQQIGTATSQPADTVASARLDLHLVREADLNPAAETAVDVDAAVDAQQRSQRASRRFRTAFASVVTDTDLSKQLTADAHEDALEDVTDDAEVGVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHK5</accession>
    <name>U1MHK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00950</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88804">
        <property type="protein sequence ID" value="ERG88804"/>
        <property type="gene ID" value="J07HX5_00950"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1933183_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="130" mass="14457" checksum="0F371679F32A2444" modified="2013-11-13" version="1">MNMKLNISLFAFSAVISRQEPTCSSKQGGAIVGGVTAVTGTAATENTSTSSNEDTFRLTPENPGFRSNGSQKTKKLTEVDYWNGSDDVASPMPVNCDDCDNLLMQADYYTKAFKIREKDQDSYYQYVYWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIA3</accession>
    <name>U1MIA3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="6" type="ORF">J07HX5_01261</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89109">
        <property type="protein sequence ID" value="ERG89109"/>
        <property type="gene ID" value="J07HX5_01261"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_3_0_2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="197" mass="20998" checksum="0E84EB430C902897" modified="2013-11-13" version="1">MNDRTAAVSRETAETSVDVVLDIDGAGDATVDTGVGFLDHLLTSFATHGLFDLTVEATGDLSVDTHHTVEDVAITLGKTVEEALGEKRGIVRFAERTIPMDEARATVVIDVSGRPYTVFEGEFSQPTVGSNGMTSQLGRHVLRSFATHAGVTLHATVMGENAHHELEALFKGLARALDDATQIDDRRSAPPSTKGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ74</accession>
    <name>U1MJ74_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01674</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89509">
        <property type="protein sequence ID" value="ERG89509"/>
        <property type="gene ID" value="J07HX5_01674"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2547636_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="82" mass="8803" checksum="3EA7F9B4A2FC54C9" modified="2013-11-13" version="1" fragment="single">WNQTGASGGAPVSVRSNSGMLSVNGKYPPAEESARTGVHAESPPLYRWVNLPALQSASDEQLLQMRRAVTDHPGDLCPRDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJE6</accession>
    <name>U1MJE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone, small heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01765</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89599">
        <property type="protein sequence ID" value="ERG89599"/>
        <property type="gene ID" value="J07HX5_01765"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_10_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15034" checksum="87274E72DC2B3C3E" modified="2013-11-13" version="1">MGNNAMIDNLAESIGDAVSGVVDRTLGGTDTTQTLRSDCLESDDAYLVVFDAPGAEPDDVQVTCEDRTVTVRLERFRPLRESFEMQLPGRGLSLTGQTTLPDGPTVIPTAGAATLTDSGTLVVQIPKHENTTQSGNPTPATDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJH1</accession>
    <name>U1MJH1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01799</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89629">
        <property type="protein sequence ID" value="ERG89629"/>
        <property type="gene ID" value="J07HX5_01799"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_11_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOP4c" evidence="2">
        <location>
            <begin position="23"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="419" mass="46133" checksum="E009D64023F355B6" modified="2013-11-13" version="1" fragment="single">MSSDLPDTDPEDVEAPAANVERVRIEDEMEQSYIDYAMSVIAGRALPDARDGLKPVHRRILYAMSELGVTAGAAHRKSSSIVGETMGDYHPHGDSAIYDTLVRMAQEFSMRYPLIDGQGNFGSMDDDPAAAMRYTEARIAPIAEEMLEDIEKDTVDFQSNYDDRLEEPAVLPAKLPNLLLNGSSGIAVGMSTNIPPHNLGEVVDATVHLIDNPDCTIGDLMEHIEGPDFPTGATIVGTDAIYSAYATGRGRIRMRADYEFEDDKLVVTELPYQTNKARLVERIAEDVTEGAIEGISDLRDESDRDGVRIVLDLKRGANPDVVENQLLESHLEATFGVINLALVDGQPKLLTLKETLVAYLDHRKAVVRRRSEHDLTEARDRAHILEGRLEAVENAEPIVTIITESADRDEARAALTGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJN5</accession>
    <name>U1MJN5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01876</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89704">
        <property type="protein sequence ID" value="ERG89704"/>
        <property type="gene ID" value="J07HX5_01876"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2127743_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="12775" checksum="1F5B60ADD0F32305" modified="2013-11-13" version="1">MSIESPLDTVHVSETARAKRDRYLTPAELRTVLRDRAGYVCRKTSPNHEGLYDKTKFIMRGQFRKTDLDIVFTVEPDRLVVVTQMSQHADSLRGRFYEQVGTTAADAVAAVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK02</accession>
    <name>U1MK02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02011</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89839">
        <property type="protein sequence ID" value="ERG89839"/>
        <property type="gene ID" value="J07HX5_02011"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1144585_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="242" mass="25192" checksum="B7BE1197006B9965" modified="2013-11-13" version="1" fragment="single">PLEPDGVIIAGDLTNNGTETQHSLAAELLSTVPAPLMIIPGNHDVKPDDTGTPAERNITRVGDHDSYPVTAGLGDTTVLGLDSTIPRQVGGRLGPTTTLPAGESRAASPDIAAVHHPIAPPPPPFRGIVDTDTHRIEQPAAAADTLTGAGIDLVISAHLHWPSVTTYRGLSVVNAPSTASFPPSYLLLEIDPEGTTVSLVPLTGSIGMREAYDYATQDDIRGRAIKRAVTDAKHNSPVSVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MUY4</accession>
    <name>U1MUY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00001</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87860">
        <property type="protein sequence ID" value="ERG87860"/>
        <property type="gene ID" value="J07HX5_00001"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_10_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="14069" checksum="CEB993724B371A35" modified="2013-11-13" version="1" fragment="single">GSRAVMVGDGVNDTPALTAAHVGIAVGSGTDVAIESADVTLVRDDPADVTKAMRIADGTIAKVRQNLFWAFAYNATLLPIASIGLLNPAVAGGAMAASSVSVVSNSLAFMRWDPDTEYRALSRRPAAWARRRLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MUZ1</accession>
    <name>U1MUZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00011</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87870">
        <property type="protein sequence ID" value="ERG87870"/>
        <property type="gene ID" value="J07HX5_00011"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_8_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="1">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="10015" checksum="9393849FC89F2962" modified="2013-11-13" version="1">MFTWSDYDEMIELANDFDYGLAAGVLTEDLTKAHQCTKDIEAGTIWVNTYNDFPAGQPFGGYKQSGIGRETAQEAVDHYTQTKTVNIALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVR9</accession>
    <name>U1MVR9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps15</name>
        <name evidence="7" type="ORF">J07HX5_00210</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88068">
        <property type="protein sequence ID" value="ERG88068"/>
        <property type="gene ID" value="J07HX5_00210"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090139_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_S15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_S13/S15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_S15P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="PTHR11885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S13_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="153" mass="16998" checksum="1EDBE17C0CC3EC04" modified="2013-11-13" version="1">MARMHSRRRGSSGSDRPAADDPPEWSDVSAEAVEERIVELAEAGHEPSEIGIKLRDEGVGGTPIPDVKLATGKKVTEILDAHDASPGLPEDLRNLLARAVRLNDHIQQHPTDYQNKRALQNTESKIRRLVEYYRGDEIDEGFSYSVSDARDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW44</accession>
    <name>U1MW44_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00346</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88203">
        <property type="protein sequence ID" value="ERG88203"/>
        <property type="gene ID" value="J07HX5_00346"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1551784_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027056">
        <property type="entry name" value="Gluconate_2DH_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13618">
        <property type="entry name" value="Gluconate_2-dh3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="18384" checksum="CDF85DE88626C5AA" modified="2013-11-13" version="1">MELTRRDAMAALAAIGVAGGVTLGAGRLDTETTVEQNEHNRLRTTMVAVATVVYPNEVSGVPAFVNGVLDGRLEDTDHAAGIQQTVAELNDRAVAWYGGPVPELSTSECDSLLREVGADTADEDPNGTTAEQVRYYVINELLFALYASPTGGKLVGIENPQGYPGGTASYSQGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW86</accession>
    <name>U1MW86_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type antimicrobial peptide transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00509</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88365">
        <property type="protein sequence ID" value="ERG88365"/>
        <property type="gene ID" value="J07HX5_00509"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
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        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="331"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="425" mass="44811" checksum="E9984068583616D7" modified="2013-11-13" version="1">MKLRDSLRLAGRSLTGHRLRSALTVVGIVIGIATVVIFASFGTSVQTDVVGEFEDTSASEIFVVSGDLEVGEFGGGGGNSFNLNQIGDFARPAVTTTDIEALRELDGVNSVILRGEVEVNELTHKNNTLLLGDMTTTTPNAFLEDDFVAGEAFEQGTEGEGEIVLSKSAAEQFESNVTVGETVELDYEGGPEEFTVVGITTSARGGFANFGPTVYAPVDPYYEEYGETAESPSQRVEQTAFRQVTLTADPNSVVDVQTEIEQYLEQESDARQILPDDVGLTVQSTADIVDGIESVLNDIIRLVSGIGLLALIVGAFGIANIMLVSVTERTKEIGIMKSTGARNREVMGLFLGEAVLLGIVGAVIGIPVGLAVGYGAAAYAEVGFTIPLGWIAGAALMGIGTGIIAGLYPAWRAARVDPIDALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWL2</accession>
    <name>U1MWL2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formyltetrahydrofolate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00497</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88353">
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        <property type="gene ID" value="J07HX5_00497"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="138" mass="14570" checksum="E5C7B98513FCCF49" modified="2013-11-13" version="1" fragment="single">ELAEQIVMAAETDSSLEHLYPIDAPIREKIETVATEIYGATAVNYGDDAATDIDRLTELGYDDVPVCISKTFHSLSDDPSQKGAPSDWTLDVQEVSPAAGAGFLVVLTDDVLTLPGLPDEPAAAGMDIDDDGTISGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP0</accession>
    <name>U1MWP0_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00527</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88383.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88383">
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        <property type="gene ID" value="J07HX5_00527"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6218" checksum="8B2B6591FCADB1C4" modified="2013-11-13" version="1">MPMSTTGTVNGLTVRTANNEPSVPDDYRDKIHKQGKMRHNSIGAGLGFYLVDTLVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP6</accession>
    <name>U1MWP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA-dihydrouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00716</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="91"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="275" mass="29076" checksum="496F7E8F02955D9D" modified="2013-11-13" version="1">MTAATVPFAPPVALASLSGRADATWARRGAAHAGAAFLGGICVDTPTREAARTMTDRGRTEFLPDDPLVFIDNQLRALRQTPILPGVNVRSTEPESTKAAAAVCRRHSAIVEINAHCRQTEMCAAGAGESLLREPPRLAAQVRAAVRAGPLVSVKLRAGLDGVSVRRVGRQAVAAGADLLHLDAMDSPDAVSAVAPLDATVIANNGVRDFESVAAYLRRGADAVSVGRPSTNPTALNRIATATERWNESQSQSQSQSRTQTQNQSRRDSTGRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWX3</accession>
    <name>U1MWX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00796</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88650">
        <property type="protein sequence ID" value="ERG88650"/>
        <property type="gene ID" value="J07HX5_00796"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172269_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12563" checksum="D5B3E48C03584B1A" modified="2013-11-13" version="1">MLLFIRFAVLCDPSSERGRLTTTERHLARLLEQYIMTVLSTADEGKFLMDTEGEQIGVVTEVDAADQTAFVEPDPSIAEAVIQGFGFGAADNDDITVPAEAVATVTDSELRVAKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWY4</accession>
    <name>U1MWY4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00806</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88660">
        <property type="protein sequence ID" value="ERG88660"/>
        <property type="gene ID" value="J07HX5_00806"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1912269_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="15016" checksum="1268A869FF232C22" modified="2013-11-13" version="1">MYAELDGADDRETTRHRMQPALTDEFFESQPETIEQILDWREEQDADKVPREAQGAAGINFDVSDRVQEIDLPTLVLHGTDDRVLPVENGKRIAEKLPGAQLKILEGAPHMLMIERSKEVNGLLEGFFTEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX01</accession>
    <name>U1MX01_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00821</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88675">
        <property type="protein sequence ID" value="ERG88675"/>
        <property type="gene ID" value="J07HX5_00821"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_709044_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="386" mass="42652" checksum="BF9004D2325E7144" modified="2013-11-13" version="1">MFRRPARWLADRGRLPPAAQAVLGYYARTGVVDLRSLWLKRRVDTVVDAMVADVFEAVENAVAEQLGRESVSLAYDTKLLLPAQLTLGYLYRRVESTERARAERLTALVVAALLDGDMRDAIADEEYGDFEFARPVSDADRRAAAETAQKVLQTRVTTALDRQPDAVGEIYDQTVAVSEQHQDQDRQFRELMTAATERDQALDQHQSRDHSAAAVVSDSPSTGNADDTPAGQALTPHERIAAEYRHASFDEPPALFDDKIRSLPYIKTQYDRVGVIYHGMIDMYRAAGFTVGDPFQRSIVLAIIGAQIWLDDIDDYRADVAAGQLTPVTAEYLLAADDSTARTAVVALTETYLRRAQRQAGKANSTLTGIATEYIYRAGDHSALPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX22</accession>
    <name>U1MX22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00841</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88695">
        <property type="protein sequence ID" value="ERG88695"/>
        <property type="gene ID" value="J07HX5_00841"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2177794_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="11668" checksum="C61D988150030A8B" modified="2013-11-13" version="1">MADPPAGTHILDEPVQLAYVGPLPVDAEPELDEQSETLEGILGSVPNSLLTMQRKPAIVEGFDTLTRAIMAECGEVDPGLNRLAAPWQTTPPAIAAVRPTRWSPRRSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX42</accession>
    <name>U1MX42_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00861</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88715">
        <property type="protein sequence ID" value="ERG88715"/>
        <property type="gene ID" value="J07HX5_00861"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="242" mass="26383" checksum="7CD4B5073FA7627B" modified="2013-11-13" version="1">MDTAVLRDDMVDSLEHETKGCVRTENISVAMRSVPRHQFLDDERGAYADRSFERFGTRVLAPSTAGRLLELLSPTPTDSVLVVGAGVGYTAGVIAEIVGARNVHAVDIARRLVSEARSNLAAAGYEAVFVDRRDGADGLPEYAPYDKILLEAAAVSPPQALVGQLAADGRLVMPLGATDQSLAVVGADSVDEFGGCAFAPMLVEGEQATTVERNRTRREDREFARQHEQKRRGWELDWIDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX59</accession>
    <name>U1MX59_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00876</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88730">
        <property type="protein sequence ID" value="ERG88730"/>
        <property type="gene ID" value="J07HX5_00876"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2695597_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="8743" checksum="CB582AE1E234CB9D" modified="2013-11-13" version="1">MYLKIFWVFFTTFATLSLFITETLLSVIHCMCDKQASTLTFCPNSKTIRTYFVSRVLLTYRRPRYDRSEDLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXR1</accession>
    <name>U1MXR1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01072</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88925">
        <property type="protein sequence ID" value="ERG88925"/>
        <property type="gene ID" value="J07HX5_01072"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2150939_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="11608" checksum="D44DAA2EC82B5F7D" modified="2013-11-13" version="1" fragment="single">MSTPSRQFNTADLTRVTAGGALVGWIGTIVLGAGLQSVVSLDIVVLGISLFWLALTAGVVAYVGPGTPSSLSRNVVWRYWLVASVLGTVVNIAAALVITTGVVTGEPLEETVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXU1</accession>
    <name>U1MXU1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01110</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-glyceraldehyde 3-phosphate + NADP(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.59" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88960">
        <property type="protein sequence ID" value="ERG88960"/>
        <property type="gene ID" value="J07HX5_01110"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069533_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047100">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006436">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01546">
        <property type="entry name" value="GAPDH-II_archae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="225" mass="23560" checksum="D782E27833CB46A9" modified="2013-11-13" version="1" fragment="single">MLRVGVNGYGTIGKRVADAVRAQPDMTVVGVAKTRPNFEADAAIRNGYDLYAAVPDRRSAFAAAGIELAGDVEQLVAASDIVVDATPSGIGAQNVPLYRDHDTPAILQGGEDAGLVDASFVARANYESVAAGSPELVRVVSCNTTGLSRLIAPLAETYGIEKARVTLVRRGGDPAQSGRGPINDVLPDPVEIPSHHGPDVNTIFPELDIDYAWYESAGNANAHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXV8</accession>
    <name>U1MXV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01130</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88980">
        <property type="protein sequence ID" value="ERG88980"/>
        <property type="gene ID" value="J07HX5_01130"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141434_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="161" mass="17214" checksum="DF984C3F0DF5FDE7" modified="2013-11-13" version="1">MSDPLPPAHADAVSTLATALTDLTEPWALTGSTSFALQGIPVEPTDIDLQTTEAGARAVEARWNEAVTDPVSYVESDQVRSYFGAISLCGVAVEVMGALQKRDADGRWTEPPAIGELRQRVTVAGTSVPVLPLAYEANAYEQLGRTSRAALLRTHAHQRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYX8</accession>
    <name>U1MYX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01404</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89248">
        <property type="protein sequence ID" value="ERG89248"/>
        <property type="gene ID" value="J07HX5_01404"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="57"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="518" mass="56330" checksum="8AAF9A1A797A0EC1" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ39</accession>
    <name>U1MZ39_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">16S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01466</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an N(1)-methylpseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyl-N(3)[(3S)-3-amino-3-carboxypropyl]pseudouridine in 16S/18S rRNA + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89308">
        <property type="protein sequence ID" value="ERG89308"/>
        <property type="gene ID" value="J07HX5_01466"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035060_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:18S rRNA aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="PTHR20426"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RLI" evidence="10">
        <location>
            <begin position="4"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Ribo_biogen_C" evidence="9">
        <location>
            <begin position="40"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="186" mass="20008" checksum="D7A334562398645E" modified="2013-11-13" version="1">MELHARYEPDDDPDKCTARQLAKFDLVELHRSDGTTPAGIVLDPFADRALSPADTNTDQLVAVDVSWQTAEVDSGGPSSGNRQGPQEATEPVPTAPSFDLAGRHRSLPFLVAANPVNYGKPFKLTTAEALAGALTILGDRDRAAELLSKVGRNETFLELNDEPLTRYAACADSTEVVAVQNEYLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZA2</accession>
    <name>U1MZA2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">Threonine synthase</fullName>
            <ecNumber evidence="5 9">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">J07HX5_01695</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5 9"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89530">
        <property type="protein sequence ID" value="ERG89530"/>
        <property type="gene ID" value="J07HX5_01695"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_4_1_2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="77"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="10">
        <location>
            <begin position="244"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="418" mass="43660" checksum="4B0F77E1307A4BF3" modified="2013-11-13" version="1">MAELALTTEAPACAETGAWLECIECGETYPPFAEVRYRCECAGLLEVRYAELPTWADFSGTGVWRYGAALPVDRGVSLPEGGTPLHEMPGLEAELGLDRLRVKHEGMNPTGSFKDRGMTVGVRVAQRAGVDRLACASTGNTSAALSAYGARAGLETLVLLPRGKVAAGKLAQASLHGARILEVDGNFDTCLDIVQALAQRGEVYLLNSLNPFRLEGQKTIGLEILEQFREEEGGYPDRIVLPVGNAGNTAAFYKLFRELVKSGALAPEEVPALTGVQAAGAAPMVEAIEEGWPEPERWPDVETVATAIRIGNPVNAPKALPGIRKTGGTAVAVSDDAITDAQRTLAAAGIGVEPASAAAVAGLRRLREAGVVTADEQVVCLATAHLLKDPEAAAVAGGDPEPVPGTVSGVREHLAESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB2</accession>
    <name>U1MZB2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01526</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89368">
        <property type="protein sequence ID" value="ERG89368"/>
        <property type="gene ID" value="J07HX5_01526"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257254_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11257" checksum="3FEBAFAE3E5BF7DC" modified="2013-11-13" version="1">MSNIDAHEHEHKHGPNYGCESCGDPRSMDFLDKYLTVWILGAMAVGVGLGAVAPSVTQPIQQFHLVEIGLIAMMYLPLAKAGHSQLRAVFSNWRILGVSLVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZC3</accession>
    <name>U1MZC3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01541</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89383">
        <property type="protein sequence ID" value="ERG89383"/>
        <property type="gene ID" value="J07HX5_01541"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2488418_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="9686" checksum="6ED54BB300978C4F" modified="2013-11-13" version="1" fragment="single">MKANLLTADGDHLPHEFRGARLTDEDGEPTGVIGVGRDLTDRQQQERRFQTLVEKSNDIISVVDASGQFQYQSPTVKPILGYDPDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZD4</accession>
    <name>U1MZD4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketosteroid isomerase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01556</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89398">
        <property type="protein sequence ID" value="ERG89398"/>
        <property type="gene ID" value="J07HX5_01556"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1801632_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15944" checksum="285EFAC3B03C717D" modified="2013-11-13" version="1">MKPVTGQYGSMSVKTAERYFELADDPDAGPAEIAALYAADATLMSPREGVFHGRDEVQQFFELNAVFFERGAHHIEQYHVDGDTVVCEGWIEGRTAAGRSYEGVGLTDIMEFNGADEIQQLRVYLDYSAILTEVPDEVPDFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZF5</accession>
    <name>U1MZF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01581</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89423">
        <property type="protein sequence ID" value="ERG89423"/>
        <property type="gene ID" value="J07HX5_01581"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2695598_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="7429" checksum="040974D3BFE89990" modified="2013-11-13" version="1">MSCLVSVSSGRIAPVGELSLLPAVCLDCPATLRAAVGRCVGGCPTPHALVMDSLVRLGTVPLLSGVVLRLIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZK3</accession>
    <name>U1MZK3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01633</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89473">
        <property type="protein sequence ID" value="ERG89473"/>
        <property type="gene ID" value="J07HX5_01633"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154325_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043816">
        <property type="entry name" value="DUF5798"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19111">
        <property type="entry name" value="DUF5798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="12668" checksum="299EBD5FE0B4D3AA" modified="2013-11-13" version="1">MDLGSTAKKLQRATTVAEKSYKRINELLDRIKRLQEDLETTSSQVDSLEREVAAQRAVLEALAEAEGVDTDAVIDAAELPSVADADDADDGDANANTDSTTDADSDDSGDTAETPAPAADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZL6</accession>
    <name>U1MZL6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylserine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89650">
        <property type="protein sequence ID" value="ERG89650"/>
        <property type="gene ID" value="J07HX5_01821"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049944_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="225" mass="22941" checksum="3F9B647E3969E925" modified="2013-11-13" version="1">MSLRVGDRLGLADAITLANAALGVVAMTAAVFGRPTTVAQLILLAAVADGLDGIIARTRGSTEVGPYLDSMADLVSFGTAPALLVFAAARDVWRLSDPGLYALAAGVAAVFVVFSLVRTALYTVYVGPDETRPGIQNTLAASILAAGYLAGLTAAPAVLGVSVVVSVLMIAPVAYPKLAARDALAMGLVQAGAIAAPTLYSRVFPRALLVAALAYLTLAPWVYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZP5</accession>
    <name>U1MZP5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01688</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89523">
        <property type="protein sequence ID" value="ERG89523"/>
        <property type="gene ID" value="J07HX5_01688"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147794_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15289" checksum="D297A21380542A3F" modified="2013-11-13" version="1">MSRIPSDHATVTSHSLAVDQVGRTSRPQLPLDSVAPFELAPGAVLSLSLLGTQSYTQLAQTLAGAPALRSAFQTRRLARVEEPTAEDNRLADWIDGAGLAAGDRVVFDVLAAGHAYGLRAPGERVVYDSPARPDPALSDIAEKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZR0</accession>
    <name>U1MZR0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01709</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89543">
        <property type="protein sequence ID" value="ERG89543"/>
        <property type="gene ID" value="J07HX5_01709"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_935697_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="297" mass="32408" checksum="AA98756CBA1DF08C" modified="2013-11-13" version="1">MTRTPSRRSLLALAASAAIGSTAGCLGSIRGGSSGQAGFRDWLTDPDVFVNEDWPTIGFSYTEDTDTDHVSKSARMTAGRMGISDVPLEADVNAYLSQWLGSILILFGEFSRLELEIGVENSENAMITGERGPYRIGKRPTLTNTESDRDEIPFAFNENVIISSFTSRGSFEAPVERCIDSKTGDTDGLEAAYPVFTQLFDRLPDLSEQTWVSGMSKWPSLWDDLDGFDANVLSVPESGTDVVRTAVFAFDDTPTEKQTQIIKQRFDSVIENADKTTTDGRFLTITGTGPEIPSAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N036</accession>
    <name>U1N036_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01850</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89678">
        <property type="protein sequence ID" value="ERG89678"/>
        <property type="gene ID" value="J07HX5_01850"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783894_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7472" checksum="77D6FFAEAF9C3E1E" modified="2013-11-13" version="1">MINDNVTQYLKKYILPGGGLTVILFTGILYDILGFWIRNIINAAIIGAVVYLLYRLVVAVEELAGNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N070</accession>
    <name>U1N070_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01885</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89713">
        <property type="protein sequence ID" value="ERG89713"/>
        <property type="gene ID" value="J07HX5_01885"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1665436_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="158" mass="18053" checksum="5DC09E5160BF203C" modified="2013-11-13" version="1">MTVRQSRTQRWVSVRDPERKQTYCTLTDDHTVIGLTAPGRARACPLTLIDRLRSPQRHVRRVGDCNLLSHLPQRDSAQALRRRADTPRHLGAALKHLADLQRRHRQDSRVFPRRDERVSNDGTPGIDNATVGSEWSQMLATALRGEHSGERMVIPMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1N078</accession>
    <name>U1N078_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsZ</name>
        <name evidence="10" type="ORF">J07HX5_01895</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89723">
        <property type="protein sequence ID" value="ERG89723"/>
        <property type="gene ID" value="J07HX5_01895"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024865_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 6 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="9">
        <location>
            <begin position="221"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="336"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="394" mass="41544" checksum="A7A049F6D567D277" modified="2013-11-13" version="1">MQEIVNEALERDEQEQTQMTDVDGFGDPRIVIVGCGGAGNNTVNRLYNIGVDGAETIAINTDKQHLKMIEADTKILVGKSLTNGLGAGGDPSMGERATEMAQGTVKDVLSGADLVFVTAGMGGGTGTGAAPVVSGIAKEEGAIVVGMVSTPFNVERARTVKAEEGLEKLREEADSIIVLDNNRLLDYVPNLPIGKAFSVMDQIIAETVKGISETITQPSLINLDYADMTSIMNQGGVAVMLVGETQDKNKTEEVVKDAMNHPLLDVDYRGASGGLVHITGGPDLTLQEAEGIAQNITDRLDASANVIWGARIQEEYKGKVRVMAIMTGVQSAQVLGPTTQKQANKSRQAIEGVDADSLDTADSTGGTHDRGRGETDGGHAQVEQQNGLDVIRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N097</accession>
    <name>U1N097_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02027</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89855">
        <property type="protein sequence ID" value="ERG89855"/>
        <property type="gene ID" value="J07HX5_02027"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1860639_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="137" mass="14954" checksum="060E5315D635355E" modified="2013-11-13" version="1">MLKTTDSSDASSSRLDLSATTIIESLPDAVVIAEAESGTVVTVNGAAEELFDCQRADLVGRNQSELHPAEDAELYEEAFRRGLKSETVERLQDGRPLYVETALGERKPVEINAQRLXXXXXXXXGRYHQPETATTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0A4</accession>
    <name>U1N0A4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01925</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89753">
        <property type="protein sequence ID" value="ERG89753"/>
        <property type="gene ID" value="J07HX5_01925"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1682625_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="156" mass="17386" checksum="C7CB497A85A562DB" modified="2013-11-13" version="1">MSELSAAEFQTVILTRWPLATVSKPTLCVGINQSRTARRSGPIVPSGIGTGSMTLAETTGLYERDSRGLTEARTRRSNPGPVAVSLCYFARWRVSPRVRNCCLCNAPRNEPDKVEPVDPDEPDCEQNRDPKWDPLAVERVDCPPQKHKTHHIVEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0C6</accession>
    <name>U1N0C6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="6">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_02062</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HTP reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89890">
        <property type="protein sequence ID" value="ERG89890"/>
        <property type="gene ID" value="J07HX5_02062"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_4_1_2"/>
    <dbReference type="UniPathway" id="UPA00275"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006401">
        <property type="entry name" value="Rib_reduct_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01508">
        <property type="entry name" value="rib_reduct_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="11">
        <location>
            <begin position="52"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="283" mass="29923" checksum="6458013B85C76915" modified="2013-11-13" version="1">MTDQTGRRGESATQSGTDGQTSTEPEIKHEGGPGSDTETQMRTTTDADDLRVVVNAAVSVDGKLSTQKRTQVAISGDADFDRVDQIRAESDAVMVGVGTVLADDPRLRVKDNGRRMARQDRGEPPHPARIVADSRARTPDDAALFEDHAQTYLLVSEAAPADRVERLRAAGATVFTAGTDRVDLAGGLGQLAATGAEQILVEGGGEIIFSLFEQGLVDRLSVYVGSMVIGGRDAPTLADGEGFVDDLSTLSLQTVNRLGDGVVLTYGVSPKSLLKAEKTIDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0W0</accession>
    <name>U1N0W0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Archaeal Glu-tRNAGln amidotransferase subunit E (Contains GAD domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_02126</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89953">
        <property type="protein sequence ID" value="ERG89953"/>
        <property type="gene ID" value="J07HX5_02126"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089863_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004414">
        <property type="entry name" value="GatE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF2">
        <property type="entry name" value="PTHR11659:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_N" evidence="6">
        <location>
            <begin position="36"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="202" mass="22476" checksum="01427B048DF22B82" modified="2013-11-13" version="1" fragment="single">MSSSDADATAETGADRGALDTDTEADEYDYDRLGLVAGLEIHQQLDTETKLFCSCPTTLRDPAEVTRRFRRRLHPTRSELGELDQAAVEESRVDREFEYLAYDSTCLVEEDDEPPRRVDDEALQVSLEIAQLLAMTPVDQAHVMRKIVVDGSNTTGFQRTMLVAGDGVVETSEGPVGIEDLMLEEESAKRVETTDRGVRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P394</accession>
    <name>U1P394_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00103</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <end position="39"/>
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        <source>
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    </evidence>
    <sequence length="124" mass="13533" checksum="8F3210445066AB18" modified="2013-11-13" version="1" fragment="single">MNRSRNVILGALCVEIVAAVSVVVYGHFALVAVAILYWIDLLFLMGRVGVQRLFAWPTRGIDMRRIATGRVSLPFRLLKHKRGAISIADSLPPVYPKNAPMAISALWWGGIISVPTVPIAALSI</sequence>
</entry>
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                <person name="Narasingarao P."/>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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                <person name="Narasingarao P."/>
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    </feature>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="38" mass="4243" checksum="D94602A902175C9D" modified="2013-11-13" version="1" fragment="single">MCYKTTIIITGSSETVDRNAGLCWWPVPRATARTLWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4R3</accession>
    <name>U1P4R3_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">J07HX5_00658</name>
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                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20625" checksum="9D0717FC94AA1BD0" modified="2013-11-13" version="1">MFAVWEFVVFPFPARCSKRRCCSWVVLSMPPVLPIAFAFRLRGRSLSDLGWWFWIWCVCRRVCGLSLLSVQSHDKRRRISGPQFGGESHPVVVLTSFVYGILVRESFLAPMSLWIGIAETGALVLVVYAFYRLGMTFETITHNPESSQLRHPEIVFPIPGLTCSSADTIRERQSRQSGKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P553</accession>
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        <submittedName>
            <fullName evidence="6">Chromosome segregation protein SMC, primarily archaeal type</fullName>
        </submittedName>
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        <name evidence="6" type="ORF">J07HX5_00823</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="5">
        <location>
            <begin position="355"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="229"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="507"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="803"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="1003" mass="112293" checksum="6F18A8737BD9F18B" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P568</accession>
    <name>U1P568_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00838</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88692">
        <property type="protein sequence ID" value="ERG88692"/>
        <property type="gene ID" value="J07HX5_00838"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1492937_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007354">
        <property type="entry name" value="CruF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04240">
        <property type="entry name" value="Caroten_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19687" checksum="5E9B894E0C2E8743" modified="2013-11-13" version="1">MSGAVARLPSTRAKLEAEFDRLIRANRFTISSFFPLNGIVLLVGSAEDWVSEPLAFHELLTMTGVLVIRSPLITGAAPIISQSPSGRHRTRRVRMHEQVYTIHTGWPYGQFEHVIDLGLEIAGVPLGLSVFFLPLVMNANLLVLLFDRPTGGPTPPERVGWIGRPTRRARSAGLSSASPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5E0</accession>
    <name>U1P5E0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor IIB</fullName>
            <shortName evidence="6">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tfb</name>
        <name evidence="9" type="ORF">J07HX5_00903</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88757">
        <property type="protein sequence ID" value="ERG88757"/>
        <property type="gene ID" value="J07HX5_00903"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043736_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="1" evidence="6">
        <location>
            <begin position="135"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="8">
        <location>
            <begin position="135"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="6">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="8">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="34954" checksum="6AECEFF3D6B04434" modified="2013-11-13" version="1">MRAKKSVKTESPSNPDTETQSEAAQTAEQQRCPECSGRVRSDDCETVCTDCGLVVDEHAVDPGPEWRSFADDDTTPERTGAPLTRSRHDRGLSTEIGYSTRVTGRKRRQLARLRRQHKRTQIRSKAERNRVYAFTEVRRLVSRLTLPKHVRDQSCVLFESAQDEGLLQGRSIEGFAAAAVYATCRTASVSRTVTEVVEAAKATRDELTVAYDALNRELGLPTGPIHPREYIARFASQLELPATVERRARSLAEEARERGLDNGRDPSGVSAACLYTAAQQTGHSLTQQAAAEVADVTPVTLRNSYYNLTDGTSDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5F9</accession>
    <name>U1P5F9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00918</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88772">
        <property type="protein sequence ID" value="ERG88772"/>
        <property type="gene ID" value="J07HX5_00918"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3243433_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="43" mass="5006" checksum="04B73B2787AE1B82" modified="2013-11-13" version="1" fragment="single">QPVYTGQSREHTPDHQITDTTDLYVLDSETLEQGDTVKRMRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5U9</accession>
    <name>U1P5U9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01038</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88892">
        <property type="protein sequence ID" value="ERG88892"/>
        <property type="gene ID" value="J07HX5_01038"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1149783_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="24648" checksum="4EEE3EE1F0CB0FA8" modified="2013-11-13" version="1">MLCTAVRSESAIGVGVTASLRSSWVVTPRSRAIRSNDVLASVTTRSMPSAVVARASGLAVTQAGATFAAPGSTDRESMVPTVEGSSCSAAAVAVCSISRANAAAAASALSSGAHRCRAGMVCLAGDGRDDADIYTGLLKCCILFDVQLEKASPPFGSDAAVAGVADLVERVPERARAASGAGVPVATEEHSRPPPNVAPSSSVKLTTVRRGTRTDPIGSLRQKCSSDRYLMSAWALPQRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5X0</accession>
    <name>U1P5X0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type transport system involved in multi-copper enzyme maturation, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01074</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88927">
        <property type="protein sequence ID" value="ERG88927"/>
        <property type="gene ID" value="J07HX5_01074"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071765_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="32266" checksum="BCED768A3EF2B99E" modified="2013-11-13" version="1">MSQQRSTPHDQPAQEQTDTQHSSRSQSRFWLHVARKDFADAVRSRLFWALSALMLLLAYVGMAVPELQVRYGGAESAAAADGVDILSDVMGILIPIIGLIVGYMAIVGERETGSIRMMLSLPLKRSEALLGKFVGRVGVVAVPIILGFALAAPFVVALYGSFPVDTYVGYVGRVVTTGIIYIAIAVGVSGSVAARGTALAFVVGIFAVFEFFWSFLLSGLYFLLNGNLDVSAGDLPTWYEAMLQLQPMSAVDNAFHGFTGISTAEPLLLQEWVSALLVLAWILVPLAIGYRRFRAADIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5X2</accession>
    <name>U1P5X2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01079</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88932">
        <property type="protein sequence ID" value="ERG88932"/>
        <property type="gene ID" value="J07HX5_01079"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1100928_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="252" mass="27869" checksum="0128D89C9B38E212" modified="2013-11-13" version="1">MYRRLRRLLRGLTPRQFTTRVEARISEGIHSLIQYERTPVFRRSQKSLVTTVIPVREPRSFYRVSGIQCPRGRVSSMDYRGAIIDVDGTVVRGKTPISGAVAGIERLRAAGIDPLFVTNNPTKPAAAYVDRLSAAGIDVAADRVVTAGTVTTQYLQQHHADAAIQLVADSGVRDQLERTDLRLTADEDATDVLVASIDREFDYDDLCRALWTLDKPEVTFIGTDPDIVIPAAKRDMXXXXXXXGLPLSRGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6G6</accession>
    <name>U1P6G6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HGPRTase-like protein</fullName>
            <ecNumber evidence="1">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01315</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May catalyze a purine salvage reaction, the substrate is unknown.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89162">
        <property type="protein sequence ID" value="ERG89162"/>
        <property type="gene ID" value="J07HX5_01315"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126376_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01467">
        <property type="entry name" value="Hypx_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026597">
        <property type="entry name" value="HGPRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="2">
        <location>
            <begin position="39"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="189" mass="20755" checksum="D9A44A67CA8F8443" modified="2013-11-13" version="1">MERLKESLLEAPIIEKGDYHYFVHPVSDGVPMLRPELLREIVIKIIRKADLDQVDKIVAPEAMGIHISTAVSLMTDIPLVVVRKREYGLADEVSISQVTGYTESEMYINDIRPGDRLLVLDDVLSTGGTLSALLTALDDIGATVADTVVVIKKVGGENKLDETRFRAKTLINVDVVDGEVVIRDEDGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6M6</accession>
    <name>U1P6M6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01382</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89227">
        <property type="protein sequence ID" value="ERG89227"/>
        <property type="gene ID" value="J07HX5_01382"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_955130_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038978">
        <property type="entry name" value="MJ0935"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42198">
        <property type="entry name" value="PTHR42198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="293" mass="32538" checksum="5F329DC682A85AB4" modified="2013-11-13" version="1">MPRTGQKVDDLATEGEHMTDALGRVLDIADEQGAVTWGDVNDDLSSGEWGRLIEKGLLVDAGEGFVVDDPDGVREALDDADPVSMDEYDTGWSSYDKGAAGIVLVLFVGYIFPPVRTAVGSNVDTLFGPIESSLPFYLVILVLALITGLHSAIMQDNLMNPEIMSAYREKTQSLKQRREAAKERGDEEELEQIQDQQVEMMTDNLGVFKAQFRPMVWIMVLVIPVFLWLYWIVRDVGVTIASPVIVFPYAGEISSWTTGLVGPMQAWIVWYFVCSMAFGQIIRKAMNVRTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6N5</accession>
    <name>U1P6N5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01392</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89237">
        <property type="protein sequence ID" value="ERG89237"/>
        <property type="gene ID" value="J07HX5_01392"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10504" checksum="799971FEF1E2DD84" modified="2013-11-13" version="1">MTVTVKDFYADWCGPCESQEQILEEVEQEYDDVEFERIDADEHQDIANEYQVRSLPTLVIERDGEMTERFVGVTQAGQIEEAVQTAQTSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P755</accession>
    <name>U1P755_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00097</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87956">
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        <property type="gene ID" value="J07HX5_00097"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2067715_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12741" checksum="064D4A15C66704A1" modified="2013-11-13" version="1">MSPDQTDSATTVTTAPVNIKIYCVIVALVSLIGVGLSLKTISTSGPTGGFGMVFLGSSAANLVVLYGLWTLKSWSWTWAMVLFFFDAVINLFPGSLAGTIINAVFIGYLWSKRDYYDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P793</accession>
    <name>U1P793_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00142</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88001.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88001">
        <property type="protein sequence ID" value="ERG88001"/>
        <property type="gene ID" value="J07HX5_00142"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080977_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007362">
        <property type="entry name" value="DUF429"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04250">
        <property type="entry name" value="DUF429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="29448" checksum="80EB70726FB20290" modified="2013-11-13" version="1">MATYVGATWASTGWFGVMLRDDDSWETDHFPTIWSLWKAHSDATRICIDVPIGLPTERKRTCDMKARRLLNERGRTVVYTPVRAAVYEQTLGDAKAITERAGYSIQNQAWSLVPRMRAVDEFLDMNPGARDRLVETHPELCFYMLNGRATVPPKTAPEGIDRRLAVLAEELEAARPIVEHAREQYLQPSYASFLRDQTTILDALVLAVTARRDQDALSVLPVRESVPRDERGLPMQMIYPRDTTQLRLSAAAADTDTNASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7A7</accession>
    <name>U1P7A7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00162</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88021">
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        <property type="gene ID" value="J07HX5_00162"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_822850_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="343" mass="37813" checksum="4567EFEA4C192626" modified="2013-11-13" version="1">MAQGLDVGTMNILSARQDENETIFVQQRNSFVEIDYSDMADQMLSRSDVLHIRKDDEVYIVGDDALEFANIFNEETRRPMQAGILSSDEQSAIPMIKLITEQVVGEPVQSDELLFFSVPADPIDDDMSMLYHQKTVNSLLSEMGYNPEPINEGMAVVYSELADQEFTGLGVSFGAGMTNICLSYYAVPVMKFSIARGGDWIDENAARATGTPVDKITSIKEDDFLLDFESDVGGAEGALSIYYDNLLDYVIENIIQEVDDEDVEEGLDVPVVVTGGTSTPDGFEELFSERLKEANLPFSISGVRRADNPMYSVAQGALVAARSEEQRAGTRADPERSEVEADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7D2</accession>
    <name>U1P7D2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01626</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89467">
        <property type="protein sequence ID" value="ERG89467"/>
        <property type="gene ID" value="J07HX5_01626"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="156" mass="17458" checksum="9DF3E0B13AE856D8" modified="2013-11-13" version="1">MLTLLQENARFSIEDIARQTELPPETVGAAIDELEQTGVVRGYTPVVDPERRGTERVRAVIELNVTLDRETSYSDIADRLAKFPAVESLELVSGEFDFMMTVEDDSMRDVSGFVSERVAPVPEITQTVTHYAMQTYKRSGIVMNDGDEDDRLSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7R6</accession>
    <name>U1P7R6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01768</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89602">
        <property type="protein sequence ID" value="ERG89602"/>
        <property type="gene ID" value="J07HX5_01768"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1307111_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="2"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="211" mass="23366" checksum="F2AA89BFC16F7792" modified="2013-11-13" version="1" fragment="single">RRLAEQADSPVPDVEIGASHLPRAASVGYRPEESVILVSRGLVDRLDGRELDAALAHELAHLLNRDAAVMTLLAFPRSKIGELSNLADRIDDAVVFLVPVFIVAIPVYTTNRLAAPMVARYREYVADHAAGELVGSHAAVAGALTTLDREYSTQYTQDLRVGWSTRAFGIVPPPWEERKVLDGALRFFYRRMLGTHPPTESRIERLRSRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7U4</accession>
    <name>U1P7U4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Type 2 DNA topoisomerase 6 subunit B</fullName>
            <ecNumber evidence="1">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Type II DNA topoisomerase VI subunit B</fullName>
            <shortName evidence="1">TopoVI-B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">top6B</name>
        <name evidence="4" type="ORF">J07HX5_01802</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Relaxes both positive and negative superturns and exhibits a strong decatenase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two Top6A and two Top6B chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TOP6B family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89632">
        <property type="protein sequence ID" value="ERG89632"/>
        <property type="gene ID" value="J07HX5_01802"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006403_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00823">
        <property type="entry name" value="TopoIIB_Trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00322">
        <property type="entry name" value="Top6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040494">
        <property type="entry name" value="Top6b_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005734">
        <property type="entry name" value="TopoVI_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015320">
        <property type="entry name" value="TopoVI_B_transducer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF4">
        <property type="entry name" value="PTHR10871:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18000">
        <property type="entry name" value="Top6b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09239">
        <property type="entry name" value="Topo-VIb_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01052">
        <property type="entry name" value="top6b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="42"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="771"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="789"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="109"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="119"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="621"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="807" mass="88392" checksum="ED0EFA596776D49F" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7W6</accession>
    <name>U1P7W6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Fe-S-cluster oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01828</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89657">
        <property type="protein sequence ID" value="ERG89657"/>
        <property type="gene ID" value="J07HX5_01828"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074745_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="19185" checksum="A4047E605AA99EAB" modified="2013-11-13" version="1" fragment="single">MGTPVPVCRRCFIQAAEATFVSLEAELEQARGLEVAALADAIEQIGFECTQCGACCTGEEDSEHTATVFPGEVRTIDAAWAEVARPMPYGLADAEDSSETFEWALQTDACGDCMFYESRDKNNEGENEGGRCGIYGDRPLICQTYPFSAVLDAASTNSDTTDDTAGQATAGVVETVGPVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P806</accession>
    <name>U1P806_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01869</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89697">
        <property type="protein sequence ID" value="ERG89697"/>
        <property type="gene ID" value="J07HX5_01869"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1017820_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="273" mass="27449" checksum="317545264D5AB6B8" modified="2013-11-13" version="1">MAVVAELLFGPDELAGLIGPAVYDALRAVTTADGVRAVLLGIAVLGFGVSRLVRAASKLANAQQQTLVQSLVALAVGSGLAVGAAVVADPIYTAIVDWTITQLPTPVQPEWRTLTEEAVELYGAPAFVLWLLTGGVLVVLAVVTVLRRVRLAGALTTGETGPALAGLGLFAAAASAGTIDAPAWLVFTGVLGGLFVWDTGRFGSELATELGHAAEARTLELVHTSAALVVGVAGVVAAAVLAGLLGNRAAASLPTLALLGVIIGLICLVAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8E9</accession>
    <name>U1P8E9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01999</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89827">
        <property type="protein sequence ID" value="ERG89827"/>
        <property type="gene ID" value="J07HX5_01999"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1998668_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="13847" checksum="5798561335A1FD74" modified="2013-11-13" version="1">MLTNGTESAASICGAILYAEQAQYYGFQAVDTRRHSVTRSTDTDRLGYSMPNTVFTPLXXXXXXXHPENHLSVFTTSSRLKLLYTGCCVHVFSSGEDPRLFLAAGRWRLSRSMADSVTRSWLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8G7</accession>
    <name>U1P8G7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00556</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88411">
        <property type="protein sequence ID" value="ERG88411"/>
        <property type="gene ID" value="J07HX5_00556"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1664309_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="158" mass="17380" checksum="ECDC3C1B54F4EF26" modified="2013-11-13" version="1" fragment="single">CPIPTRSPGWGRYMLSGVRRPCTCESDLSVLSVATRPSQQLRRAPPVLVTSAWRRCAIVLPVASKQSGLSPTLTPVSLPRHSARIDILPRLKTRAFSSPYCNRPRPTARGGWRFVCTVFYRDWRWGLGPSCCPLGLSVDLVSTPGEARGFSLVAPYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8M3</accession>
    <name>U1P8M3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00626</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88481">
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        <property type="gene ID" value="J07HX5_00626"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="2">
        <location>
            <begin position="20"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="310" mass="32390" checksum="4E847F6611B8582A" modified="2013-11-13" version="1">MFTYVGPISSVHESILETIGSPLVAVDAPADARIAAKLESYNPGGSAKDRPALAMVEAAEEAGALDETTTIVEPTSGNTGIGLAMVGAVKGYAVRVVMPASKSAERRELLRAYGATVELVDGDVSAARARADELAEQPEYVQLRQFENSANPQAHYRTTAEELLEQTEDAIDAFVAGVGTGGTLSGAGRRLSEAFPEMEIVAVEPTENAVLTGEPAGNDGYQGMGPGFVSENTDTELIDAVETVSLSTAEQECRRLARNEGILAGQSSGASMVAARRVATRLATTATAPLVVTVFWDSGERYLSAGTFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8N9</accession>
    <name>U1P8N9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00646</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88501">
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        <property type="gene ID" value="J07HX5_00646"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2695596_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="8121" checksum="12AA2F5BF540A319" modified="2013-11-13" version="1">MIGTNALRYSQSARWVFTIACLIISWGWFLGLATAGWLLGDTIVNDSRLEYLNTLSAAIIWAGALYMMITVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9A7</accession>
    <name>U1P9A7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00867</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88721">
        <property type="protein sequence ID" value="ERG88721"/>
        <property type="gene ID" value="J07HX5_00867"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020820_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="5798" checksum="884A0DF27FD785C2" modified="2013-11-13" version="1">MVSDVVNQLAVACPVCVTVHEDGSKTTGLEAEIEVVGVVEPLGDAFRTDQPRTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9G2</accession>
    <name>U1P9G2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoenolpyruvate synthase/pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00917</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88771">
        <property type="protein sequence ID" value="ERG88771"/>
        <property type="gene ID" value="J07HX5_00917"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1520878_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEP-utilizers" evidence="2">
        <location>
            <begin position="61"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="177" mass="17890" checksum="13F8A18983D450F0" modified="2013-11-13" version="1" fragment="single">NGTENGEIMVEPGVADGGDKSNNSSESDEGDSVALSGLGASPGTVSGEAKIIDKLDGLDKVSDGDVIVAKMTTPDMVPAMKRASGIVTDEGGMTSHAAIVSRELGVPAVVGAGGATASLQDGQLITVDGEKGSIETGATASEDEDNTKRYQHRRGGQARHTGQTNDGDPGESKRLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9X9</accession>
    <name>U1P9X9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01042</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88896">
        <property type="protein sequence ID" value="ERG88896"/>
        <property type="gene ID" value="J07HX5_01042"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2745700_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7398" checksum="55C95CE0B5485804" modified="2013-11-13" version="1" fragment="single">GLSAAGCLNSNSVNPRLHSVDISNRTDKLVEFMLLVRTPETAVFETSTTLQAVGECGGLRSTTRGRTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA49</accession>
    <name>U1PA49_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01131</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="164" mass="17803" checksum="085983E4A25681EA" modified="2013-11-13" version="1" fragment="single">MPVALGEPAPLSEPVPDPVGGHANNIADGRKFSRCPEVQMAPRAGADDIGRFVGLDEFPRSLERAQSPDTGSALGTHDWSKREFDPDVVVRSRPRGNVIEGAVLFGRRMRQDIDGRLLDCPPVDYRVAAVNSKNCCLVTLCVNRVCCLPRRCGCDLESVDTSIS</sequence>
</entry>
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    <accession>U1PA89</accession>
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        </lineage>
    </organism>
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                <person name="Narasingarao P."/>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="120"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="ERG89021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="14303" checksum="1747A3559B184DFE" modified="2013-11-13" version="1">MTNTQQHKQKARQAQQKAQRNRDTARAKLLQQRKALAARRARNRRESRQRRADTNTSQRSTAHSTMPSQETNEQQSVQHAHSTVPAVPAHSTVPARERLYGQRLHTVTAGETSVGSRNQDAETAADE</sequence>
</entry>
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    <accession>U1PAA5</accession>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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                <person name="Narasingarao P."/>
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            </authorList>
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        </citation>
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    </reference>
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            <begin position="34"/>
            <end position="53"/>
        </location>
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            <end position="96"/>
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            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15809" checksum="F82C5E780CC8BEA0" modified="2013-11-13" version="1" fragment="single">MDDGLTNQLLDGSTYEQATVNVRRTFPLTIDQKILIAPASLALAVLFAPLLYYRRALVTELEDANSTAAALTIDAGALAFGGIISVSGAGVLLLYLRKRIQAVDLNPERARRVVRVEDLLMWVLLQGGAFIIIAVAVAAFGVAAPETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAC4</accession>
    <name>U1PAC4_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG89051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="158" mass="16864" checksum="311C810A681CDA3B" modified="2013-11-13" version="1">MKRRSLVAALGTAAITSLAGCNVLSDDEPPAGSLQIENHHDLPHTVRMIITDVGSDGITTDDGYDVRGDVTVPPSQRRLQSSISLSPNKIKTFETIFTEPVTYAVVFAVDDAVTETAYPFSPRRSSPGSYAYLNAEVYADGEFSASFATTGLSGPFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAC9</accession>
    <name>U1PAC9_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="126" mass="14302" checksum="FA001353296FABB8" modified="2013-11-13" version="1">MPTTNDETPTDTSDRGERWHENATDADTPRETPVKAACLFCKCTTTPNDRIALETGEYLCSACHGDVREFNRSMHAHLWVSEELAGIRRILLDEWQEGTAALATDNDETESLPRRRSNADEYQFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAT9</accession>
    <name>U1PAT9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Thymidine kinase</fullName>
            <ecNumber evidence="2 8">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="10" type="ORF">J07HX5_01371</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89216">
        <property type="protein sequence ID" value="ERG89216"/>
        <property type="gene ID" value="J07HX5_01371"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="21553" checksum="A1539BC2C4D80C16" modified="2013-11-13" version="1">MYDTHITNSGHTEAIVGCMMAGKTSELIRRIQRSQIAGVDCELYKPVIDNRYGTETIKGHNGLEIEAVPVESSATVPEQLADPDVVALDEVQFFAAEPLTETIETLAADGVRVVAAGLDLDFRGEPFPATRELIARAEYVDKLRAVCAVCGEPATRSQRLLSNEPAPADSDRVLVGAEETYEARCRTHHTVPASADKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB77</accession>
    <name>U1PB77_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01489</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89331">
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        <property type="gene ID" value="J07HX5_01489"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1631583_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="162" mass="17786" checksum="3A69B3482D6D3493" modified="2013-11-13" version="1">MLSPEAGGDDADIRRRLQQAAGDAESPTEFFEQIETILSDLNGEPVDIDGLAAAAESASANGESTRSADLAEELKDSIDELSRLQESIRSSGGPGRSTTSDGRQTKRFDTNSSRTDDRLVVSRLNTLIETIQEQVEEFDRSRRLQQCRRRPEKCPGSDRVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB89</accession>
    <name>U1PB89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01499</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89341">
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        <property type="gene ID" value="J07HX5_01499"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="4716" checksum="CA0B0F3EC54F1178" modified="2013-11-13" version="1">MRIAVPNKGRLHEPTIDLLERAGLHLVDAPIASSTRRRPTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC82</accession>
    <name>U1PC82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01873</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89701"/>
        <property type="gene ID" value="J07HX5_01873"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2390924_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="10739" checksum="294E113F6C7B8126" modified="2013-11-13" version="1" fragment="single">MEPTAWSFLTVNMGTVRHGLANTACDGWNSNAWSSCRVCWRRRRAGQPGNTPEAVVIRYYHAADKPTRGSCFLTCHFACAYRIDVRSETPVDTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC99</accession>
    <name>U1PC99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactoylglutathione lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01888</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89716">
        <property type="protein sequence ID" value="ERG89716"/>
        <property type="gene ID" value="J07HX5_01888"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165171_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="12315" checksum="F98D867258EAC1D4" modified="2013-11-13" version="1">MLGRLSYATVLVDDLDRAIEFYTDTLGMELREEFELPNGRRWVSVAPPDESFPRLALATPDRDXXXXXXXWRRSAVRSLLAGVPADLGPRVTADRLTATPPVSTHLVMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCR3</accession>
    <name>U1PCR3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide reductase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02033</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89861">
        <property type="protein sequence ID" value="ERG89861"/>
        <property type="gene ID" value="J07HX5_02033"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053322_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="338" mass="39282" checksum="B16630E72AED36CF" modified="2013-11-13" version="1">MSKSEDTETSDSTETDIFSERTQLKPYEYGDFLDYVDAIRNSYWVHTEFNFDGDVQDYKVNTTPAEKTVIKRTMLAIAQIEVQVKTFWSDIYEEMPKAEVGNVGMTFAESEVRHMDAYSHLLDILGITDDFEHVTEEPAIKQRIDYLDSYLEKGNSDDQQEYIKSILLFSTFVEHVSLFSQFLIMTSFDKHEKKFKGIANAVEATSKEEQIHGLFGQELVETIREENPELFDDDFEADVQEACQEAYEAEMAILDWIFAEGELEFLPRAQVDAFLQDRFNQSLENVGVAPVFETDDELLEETRWFDEDIMMTKDNDFFSKRSTTYNKHTQSVTADDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCR7</accession>
    <name>U1PCR7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02043</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89871">
        <property type="protein sequence ID" value="ERG89871"/>
        <property type="gene ID" value="J07HX5_02043"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754628_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15421" checksum="233D1112FA5AA5FE" modified="2013-11-13" version="1">MVALGEGEATELLDRPTTEAEYRTLARRKTGALFRAAAELGAIAAAATPFTTEAVGQYAEHVGIAFQMRDDVLDATADSDRLGKPAEQDSALDRPSILAVTDYSPAAVTNLAQQEAATAVDALAGVDLAPEDMSSLEALATAAAERDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFW9</accession>
    <name>U1MFW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00211</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88069">
        <property type="protein sequence ID" value="ERG88069"/>
        <property type="gene ID" value="J07HX5_00211"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036273_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="385" mass="38612" checksum="A5684A451E25B2E3" modified="2013-11-13" version="1">MATTGRADTEPPSSLADRICDAGFVQLSAAPAGDALGAAALLAETLETVETPYQLSVATPTDGLRATDAELTIAVGHKPRGADAALDGHAPLSRRAYTIATDVGGASPVLAAAGAIAAGTAPAPTALGESDEPTASVSLERRAGLGSPPVAPADGLAHSTLLHTSLSGRPDRAAELLNNRLPAAASRSEPKPESGSGSEHDHVRRRTVASMAALTVAAEASTPAASTAVERALRPLTGGPLGTAAGLGDVLDVLADSDPGLAVAAALGHADESAVLSAWRTGATRVHDAVRDADLTRHDGVVVARTTADPPIAPVARLCREYRSPEPTVVVATESSATAVTTPGDGPDLAEATGQHTDVAGTTDRVRCSDPTATETIVDTIREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGB8</accession>
    <name>U1MGB8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00397</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88254">
        <property type="protein sequence ID" value="ERG88254"/>
        <property type="gene ID" value="J07HX5_00397"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_1_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="8">
        <location>
            <begin position="26"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="666" mass="75920" checksum="236E0150C44E6CEA" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGI2</accession>
    <name>U1MGI2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00468</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88324">
        <property type="protein sequence ID" value="ERG88324"/>
        <property type="gene ID" value="J07HX5_00468"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025112_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="54"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="4">
        <location>
            <begin position="303"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="66"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="41832" checksum="4B86FFFF8FD6F007" modified="2013-11-13" version="1">MPDDPDEGMLSWDESVFQDERVFEIDYVPETFRHRTGQMETLKYALKPAVRGSRPLNVTAHGPPGTGKTTAVQILFRELQASTDVRTVRVNCQVNSTRYAVFSRLFEGVFDYEPPSSGVSFKKLFSQVTDQLVDNDEVLVVALDDINYLFYESEASDTLYSLLRAHEERGGARIGVIVVSSDLELDIIETLDGRVQSVFRPEDVYFSAYKQAAIAEILTDRAARGFHDDVVGAPVLDRVAELTADQGGDLRVGIDLLRRAGLTAEMRGSTTVEHDDVETAYETSKHVHLSRRLRELSDSERALVAVVADHDGERAGAVYEAFHDQTGLGYTRYSEIVNKLNQLDILDASYADVDGRGRTRELSLNYEPAAVTDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH11</accession>
    <name>U1MH11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00700</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88554">
        <property type="protein sequence ID" value="ERG88554"/>
        <property type="gene ID" value="J07HX5_00700"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1753411_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="15689" checksum="F1B6AFC90F02FCDD" modified="2013-11-13" version="1" fragment="single">SGGLFDVEVVGNVVAVRDGSGLIERCPECGRVIDGGQCRSHGAVEGEDDLRIKAIVDDGTGTVTAILDDELTAAVYGGGLEQAREHARDAMDRSVVADDIRETIVGRAFRVRGSLTVDEYGANLTASTFEERDANPAARAKTLLEEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH68</accession>
    <name>U1MH68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00785</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88639">
        <property type="protein sequence ID" value="ERG88639"/>
        <property type="gene ID" value="J07HX5_00785"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2475871_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="9151" checksum="5101C74CA69E223F" modified="2013-11-13" version="1">MALNRVKQLLMTIGLLTVLGMLAVVGLMTYLWYDTRDIETDATADFDASVETDDGFEASVEAGAEAEAETEAETETGADGGEDADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH71</accession>
    <name>U1MH71_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00790</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88644">
        <property type="protein sequence ID" value="ERG88644"/>
        <property type="gene ID" value="J07HX5_00790"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353115_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10581" checksum="1AAB6DE5F2B27E82" modified="2013-11-13" version="1">MAFNCDGAVVITADGTIQQQMCRMRSPGAEVVTAHDSDDPADWMGTKHLSALEASIREEVLAAVTLSEEDGRVTVFENGTYKHYPRQELGGQWRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHY5</accession>
    <name>U1MHY5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="4">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="4">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxT</name>
        <name evidence="7" type="ORF">J07HX5_01092</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="4"/>
    <dbReference type="EC" id="3.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88944">
        <property type="protein sequence ID" value="ERG88944"/>
        <property type="gene ID" value="J07HX5_01092"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069674_2_0_2"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="54"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="141"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="20786" checksum="8CB4FF23D3D4C59C" modified="2013-11-13" version="1">MELTAGVIAVQGDVSEHAAAIKQAGGAHGTETTVREVRESGVVPDCDVLLLPGGESTTISRLLAQAEIAEEIIAHVDGGKPMLATCAGLIVAAEEANDNRVETLDLLDVSIERNAFGRQRDSFEAELTLAGLADPFPAVFIRAPVVDRVGDGVEVLARWDGDPVAVRQGPVVATAFHPELTGDPRLHDLAFFGSETTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ15</accession>
    <name>U1MJ15_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01582</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89424">
        <property type="protein sequence ID" value="ERG89424"/>
        <property type="gene ID" value="J07HX5_01582"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504834_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9826" checksum="3945C70B3CB8A1D8" modified="2013-11-13" version="1">MLDKIGSQSGKFMSIVCYYATRNAILACRHVSTTPVYRSRDAHHSRYCTGCIYWFYLSYLLHTAKLAVNRRERSSRSVSLSQLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ32</accession>
    <name>U1MJ32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_01608</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89449">
        <property type="protein sequence ID" value="ERG89449"/>
        <property type="gene ID" value="J07HX5_01608"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010057_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031803">
        <property type="entry name" value="BAT_GAF/HTH-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15915">
        <property type="entry name" value="BAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="16"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="148"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="222"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="654" mass="72656" checksum="43B97F9C98210306" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJI1</accession>
    <name>U1MJI1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01809</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89639">
        <property type="protein sequence ID" value="ERG89639"/>
        <property type="gene ID" value="J07HX5_01809"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712653_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="72" mass="8451" checksum="AA11B756E1125B71" modified="2013-11-13" version="1">MYCHRTIVLLYRIIKQLYDLIKSGADAVDFTNEPDGVSRLRNQRRHEENHKEPSVVTDFSDAQQLMFPDNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJL0</accession>
    <name>U1MJL0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate carbamoyltransferase, catalytic chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01846</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89674">
        <property type="protein sequence ID" value="ERG89674"/>
        <property type="gene ID" value="J07HX5_01846"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1773097_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="15761" checksum="5A2317A27FF9359F" modified="2013-11-13" version="1">MRMRRTQITSAKQLSRDDIKPVLDRAAEFAADPTAHTDRWPSALLGLAFFEPSTRTQMSFAAAIKRLGGDIVDMGGVDTSSVTAVPARKPTASAVGGSAYTETNKPPPTALLTHRHRDKQLILASRYCETDGVGYNSDCSGLPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJQ6</accession>
    <name>U1MJQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01901</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89729.1"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53335"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="44"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="114" mass="12100" checksum="D84AA8907C625687" modified="2013-11-13" version="1" fragment="single">MSGLTDSFYDRWTRLYDRVATAPGVRSWRGWAARSLALEAGDTVLEPGCGTGANFPYLREAVGHAGTVVGVDLVGAMLDRAQTRAADAGWQNVHAVRADATRLPVGQVDAVLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJT6</accession>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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        </lineage>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="160" mass="17918" checksum="26CFAE2A9D9F301F" modified="2013-11-13" version="1" fragment="single">MNESQRTRGKAIHRETGQTFYYATRLLPEDIREQTYVLYGFFRIADEVVDGDVQRPPAEQRDQLEEIRAAALGKTSTDEPVLEAFAEVREETGIPEGEINAFIDAMLADIGTDRYETYEALAEYMRGSAAAVGNMMLSVMGTDHRDQARSRAMALGTRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK46</accession>
    <name>U1MK46_9EURY</name>
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        </submittedName>
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    <organism evidence="2">
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        <lineage>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="79" mass="8615" checksum="4ABFEB6D3FC3DDDD" modified="2013-11-13" version="1">MGVKHIVARLGALRNRVPWWYFVIAGVVAGYQSVTVFLGVFDPPFWPFADQIYAVYCAGVTVTALPSAYSAQRSAESAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVE2</accession>
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        <submittedName>
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    </gene>
    <organism evidence="2">
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        <lineage>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG87928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3531" checksum="58E220C15C34BAD0" modified="2013-11-13" version="1">MSVSETPVGVNHLTVVPENAEADSEIETTEDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVS5</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10243" checksum="5BA68F3205BBCF1E" modified="2013-11-13" version="1">MPHNSTHMEIWALIGAYLVGFLAFHAYLRSDRSFPTSGVAAATSTADAAPTPELETSDNDCTLCPDCGASNRSEQPFIRCCECATQLPDTAETASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVY5</accession>
    <name>U1MVY5_9EURY</name>
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        <submittedName>
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        </submittedName>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88285">
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        <property type="gene ID" value="J07HX5_00428"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4604" checksum="CFF0B2C820CB48AE" modified="2013-11-13" version="1">MLNTIDVQSQIDRLETIAETLEEDEIDLATAKQLRTEIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVY9</accession>
    <name>U1MVY9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BPD_transp_1_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00291</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG88148"/>
        <property type="gene ID" value="J07HX5_00291"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529171_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="BPD_transp_1_N" evidence="3">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="19349" checksum="3FA439E7E5C74242" modified="2013-11-13" version="1">MSRGRYLAKRLVLSIPVLVVGATLTFVIFRFGPIDPAAAIVGEAATEESRAEYEQIRQQLGLEQPVMAHYRKFIIDFFTFNLGQSWVVAPGTAVTDLLLIYGPRTLWLAFWAVLIPIFVGIPIGVYAGLNANTLTDYGLSSFGIVWRAXXXXXXXXFGVTRKSVLFVLMSTSSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW31</accession>
    <name>U1MW31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00474</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88330">
        <property type="protein sequence ID" value="ERG88330"/>
        <property type="gene ID" value="J07HX5_00474"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_196473_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="71" mass="7648" checksum="A559A273125973D4" modified="2013-11-13" version="1">MNLSFIHKNIKNAALNTLFRSLEHVGMVHSKRTPVETALPIFASDTGSDTNLQRVIETGSPALKKAASAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWA7</accession>
    <name>U1MWA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00411</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88268">
        <property type="protein sequence ID" value="ERG88268"/>
        <property type="gene ID" value="J07HX5_00411"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1153727_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="240" mass="25732" checksum="BA03B7C98CF72F00" modified="2013-11-13" version="1" fragment="single">CGSLTMDADVLVAGETGSVEAPSTVVLIEAEKTILVDTSFGEPQLMAARHPGFACHRGPDQSLRAVLDSEGYVPGDINAVVLTHLDWDHCYNLTLFDSTTTVYVQQDELEYATAPYPMHATRYEADADNREPPWHGTDLTPVDGKTRLCPGVVLFPTPGHTVGHQSVAVATDDGTTVVAGDAVPTFDNVSLPAATPRQRGLAMDDIAWWESATDVLTRGDRILPGHEWAILDATPAGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWG3</accession>
    <name>U1MWG3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00462</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88318">
        <property type="protein sequence ID" value="ERG88318"/>
        <property type="gene ID" value="J07HX5_00462"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2856969_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="6580" checksum="B3746013D07F0060" modified="2013-11-13" version="1">MQTADDAGVPVRVRRVVELSGVDLFGSLAGLAVGASALGVLPAGTAGLLADNALEMVFQRHCWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWJ7</accession>
    <name>U1MWJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cystathionine beta-lyase/gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00656</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88510">
        <property type="protein sequence ID" value="ERG88510"/>
        <property type="gene ID" value="J07HX5_00656"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="439" mass="46534" checksum="2625E0D36289806E" modified="2013-11-13" version="1">MTHYNSAHDDYGTDAEDSVSAATTDTDTGANATTEAETEANAEAEATTPDTNATEHAARIETQAIHAGQSPDRDTGAVMPPIYANSTYVQDAPGEDRGYEYSRTGNPTRTALEDNLAALEGGAHGRAFASGMAAINTVLNLLEAGDHVIAGDDVYGGTYRLFREVYEDYDLSFSFVDTTDTGTVEAAVRPETALIWVETPTNPLMQINDIAALADLAHDADALCAVDNTFATPYLQRPLAFGADIVSHSLTKYLGGHSDVVGGALVTDNDALDEQLGFYQNSVGATPDPFTCFLVLRGTKTLPVRMDRHTANAQTLAERLAAHPAVEQVYYPGLANHPSHDLAAEQMDAFGGMLSFELDATLDQTSTFVSETTVFALAESLGGVESLIEQPATMTHASIPRDERLAAGLTDGLVRASVGTEHVNDLWADLEAALDAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWK8</accession>
    <name>U1MWK8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00671</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88525">
        <property type="protein sequence ID" value="ERG88525"/>
        <property type="gene ID" value="J07HX5_00671"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
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        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="22"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="39959" checksum="E0C1B63F15ADC057" modified="2013-11-13" version="1">MDYETPQFFRVMQYATQADHDVVDMVSGSPDWEPPTALREGLSEYADADPDAFQYPPSVGLTALREEIADRRGLDPEQLIITNGAGEANHLAMAGGLERFSGEEVLLTDPVYPYYAGRANFLDAEPTYVPTGPDGHLDPDTVRAHASRETAVIVVNSPNNPLGVTYDADTIGALVGIAEETDALLVSDEVYDQFDYSGRFASALAVASDHRVVTNSFSKSMAITGFRVGYAVFPTEALYERARTRHMLSTVTSSRPAQAAVLQALRDTGPGYYETVRDRLKERIDRFTDALAAAGAEYIEPEGALYVMARLPGVSGTFESVEQLIDEAGVAGMPGVSFGTEYEDWIRFALVTPRVEEAADRLTAQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWU3</accession>
    <name>U1MWU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00766</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG88620"/>
        <property type="gene ID" value="J07HX5_00766"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1614198_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="164" mass="16980" checksum="AB4D5F1CF918335E" modified="2013-11-13" version="1" fragment="single">PTVERLLVGVLTPPLRLLGRVIPRQSPPSPNRIETGFERFFESIEQLATDRRRVAAALVFSAGGLGLQAGAMWVTFLALGTHISPTVPLFVIPVGSIASTLPTPGGLGAVEAAHLGLLTGVTAAPVAVVGAAIVIHRLGGFLLTNTLGGGALVLLRVQERTDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWW0</accession>
    <name>U1MWW0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH bat-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">J07HX5_00608</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
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        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6439" checksum="6235F7177D0896B7" modified="2013-11-13" version="1">MGFFIRPQGATAGEVADALDTSRSTVTRRIRSGESTVFANLVNASAPQAAADDESPADDVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX47</accession>
    <name>U1MX47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00866</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88720">
        <property type="protein sequence ID" value="ERG88720"/>
        <property type="gene ID" value="J07HX5_00866"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3003006_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="56" mass="5869" checksum="FE10CB066DB87A1D" modified="2013-11-13" version="1">MSYGIGRGQQGGCLSASPNVEETEQAGISSSREVAWGSQLFDRLQKGCPVAEHGCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXF9</accession>
    <name>U1MXF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+-dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00829</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88683">
        <property type="protein sequence ID" value="ERG88683"/>
        <property type="gene ID" value="J07HX5_00829"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="46645" checksum="6C3B3A4569AAFFAB" modified="2013-11-13" version="1">MISATALNAVTTLWQRYRAVPIVYRIGAAFVLGSVVGLAAPNRAVQLKPLGDIFVRLLSMIVVPVIIFTLLMGIRRISPSTLSRIGWQVVGLYAILSSVAVAVGLAVANLINPGAGFDLDVDSQDAEKYQGADQPSLVDTLISAVPENPFNAMAEGNVLAIIFFVITLGLSLLLVQENTDDDRLQQSIESLFAAVEAITEALFKLVWGIMEYGVIGVFALMAAAFGNAGADALMPILMLSGTLLAAICFHIAVIYLGGLIFTVTRQSPTAFLTGAKDAIVTALSIRSSSGTLPVTMNNADKNLCIDESVYGFSLPLGATINMDGTAMYHGIVAVFAANIAGVSLGLDQQVAIVLTAVLASIGAAGVPGGGFILIAVVLQQAGLPVEVLAFIAGVDPILDRIRTMTNVTGDLAVTTTVANWNDAVDFTSGSWAGQAGDTSVGSNTPTEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXI6</accession>
    <name>U1MXI6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone, small heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00864</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88718">
        <property type="protein sequence ID" value="ERG88718"/>
        <property type="gene ID" value="J07HX5_00864"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_8_8_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040612">
        <property type="entry name" value="ArsA_HSP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17886">
        <property type="entry name" value="ArsA_HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="41"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="14599" checksum="B277B53BB89DBE05" modified="2013-11-13" version="1">MRDDDRDDPFEELFEEIERMMNEMMGPNAGGNFRVEHPAGASESSRDVHVDIQETESEIRVIADVPGVERDAIELQCDGKTLSLNAAGPEREYNEQVSLPGRVDEHSASATYNNGVLEVAFDRVDGSTSIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXL1</accession>
    <name>U1MXL1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01011</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88865">
        <property type="protein sequence ID" value="ERG88865"/>
        <property type="gene ID" value="J07HX5_01011"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="253" mass="27907" checksum="5A69F1D964AAD55D" modified="2013-11-13" version="1">MSTAARLQAVFDDRTVKDTLLAAIPAALAIALGVVPLVLLFVESIRPIPTAEQYRAVTEGIYFDVIVQSLFVGVLLTVICLAIAYPVTYWLANHCPVRYRLPALAALTLPLWLNYVVLNYTWVWLLAPDGVINVVLGGLGVVSEPLQLLGESHALPAVDLTFPSVSLILGFVHIYLPYVLLTMYVSMERLDYRLVEAARDLGXXXXXXXTTQFRQVLDNQFASALSMTFLAIIIIGIVIGARSESVRTELKQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXM7</accession>
    <name>U1MXM7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01031</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88885">
        <property type="protein sequence ID" value="ERG88885"/>
        <property type="gene ID" value="J07HX5_01031"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178115_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11206" checksum="392297DEB6DD9E32" modified="2013-11-13" version="1" fragment="single">GDLRSENVLVYEGELYFIDATNVAVDAREDARAYDVASALASLSPLVGAGRSVETALTEYSASDLLEARRFLDFVAIRPDHDFAAATLKGEIEKRAADANLQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXS0</accession>
    <name>U1MXS0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01082</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88935">
        <property type="protein sequence ID" value="ERG88935"/>
        <property type="gene ID" value="J07HX5_01082"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2627440_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8190" checksum="01F2894D3815C7F4" modified="2013-11-13" version="1" fragment="single">MNGRESLRVAWRAIAGHKLRSSLTTLGVIIGVGTVIVFVVLGGAFEANIVADIEDDSDGTGMLVNTQQVGNGGFQFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXX3</accession>
    <name>U1MXX3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gas vesicle synthesis protein GvpO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01150</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89000">
        <property type="protein sequence ID" value="ERG89000"/>
        <property type="gene ID" value="J07HX5_01150"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1582846_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008634">
        <property type="entry name" value="Gas-vesicle_GvpO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05800">
        <property type="entry name" value="GvpO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="168" mass="18312" checksum="7BBEA01207AC8D9B" modified="2013-11-13" version="1">MAESPQTQTNGSDADTDERTPTDDARDHEAEAPAEKKTDPSTARDRTPANQPAPSEPATDSTATAGADTATDTPEQTAAASSFGLLEARERAHEMASELFEHEFDSVIKINKNDNGTWRTVVEVVERSAVPDTQDILGRYEIVLDSAGNATQYELLERYQRGAMKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY28</accession>
    <name>U1MY28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01222</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89070">
        <property type="protein sequence ID" value="ERG89070"/>
        <property type="gene ID" value="J07HX5_01222"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441213_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019204">
        <property type="entry name" value="DUF2070_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09843">
        <property type="entry name" value="DUF2070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="599"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2070" evidence="2">
        <location>
            <begin position="8"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="624" mass="66376" checksum="3008C80E4D7E9A04" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY36</accession>
    <name>U1MY36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar kinase, ribokinase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01232</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89080">
        <property type="protein sequence ID" value="ERG89080"/>
        <property type="gene ID" value="J07HX5_01232"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="60"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="320" mass="32701" checksum="D2C9356FA1E2EC30" modified="2013-11-13" version="1">MVETAGPRVVSLGSINIDRVYRLDDATLETLADRPWLPERGETVAVDTPPDIPLEPDAIHHGGKGANQATAAAAAGTSATMLGRVGPDHTEYAVRSRLATDGVAADDVETVAASTGTAHVFVDADGNNRILVYAGANNAVDEKYINAHYETILNADCLLLQNEIPVAPVAGLLDHLDAASDPPLVVLDPGPPQNVDQLLAAGSVTHLTPNEQETTALGALDLFDGTMVATRGSGPVIITAPDGHQTVVRPPSVAAVDTTGAGDVLNGYLAASLADGVSLREAVARGVAAATLSTRSAGARSSVPDQQAVAAFRAEHGSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY53</accession>
    <name>U1MY53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01252</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89100">
        <property type="protein sequence ID" value="ERG89100"/>
        <property type="gene ID" value="J07HX5_01252"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021603_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="188"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="160"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="284" mass="28833" checksum="D346C2E392CC3404" modified="2013-11-13" version="1">MQVLVHGGAGDVPPDPVPRQRVLDQAAARSTDSETALAGVVAATRVLEADPRFNAGVGSAVQSDGQIRTDAGVMTPTETGAACSMLGVEAAVEVAQAVAKKTPHVLVAGTQAVGLAETVGVATDCDLWTDRRKEQWSDYDPPAAVDDQLAWVRETFAGTDTVGAVATDGEELAAATSTGGRWCALAGRVGDVPQVGAGFYTTDTVAVSTTGAGEQIAEFGLARAVAERVEDGRSPDAAAQETLTRFEAATDAVAGVIVTATSGAYGTAFNTNAMQTARAGHVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYE9</accession>
    <name>U1MYE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01199</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89048">
        <property type="protein sequence ID" value="ERG89048"/>
        <property type="gene ID" value="J07HX5_01199"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1425050_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="20076" checksum="A32E78F421C9C147" modified="2013-11-13" version="1">MSSGYSIAQTACVAVSERVRRHTEHPTRRAGQRGRTRRSRSRPSCLDLGQRGCCVDRECPPGLSRHRWQDDCGEPAGNRYPADLVSDCQSPTLHCPEQQAACRVQTPARTGTTSAVASHPVSSNPRCSESTLNTSQSASAVAAAGVSDELMVTDTASARDDAVVVAVRCARGSRSPVISSPSAPTHSTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYM2</accession>
    <name>U1MYM2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S27e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps27e</name>
        <name evidence="4" type="ORF">J07HX5_01281</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89128">
        <property type="protein sequence ID" value="ERG89128"/>
        <property type="gene ID" value="J07HX5_01281"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199465_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_S27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_S27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="5970" checksum="18E69E7F1D7F6606" modified="2013-11-13" version="1">MAGNFYRLACPDCSNEQVVFEKAASAVDCHVCGHTLVAPTGGTATLEGEIVETVEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYQ9</accession>
    <name>U1MYQ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-coenzyme A synthetase/AMP-(Fatty) acid ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01321</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89168">
        <property type="protein sequence ID" value="ERG89168"/>
        <property type="gene ID" value="J07HX5_01321"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="3">
        <location>
            <begin position="87"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="174"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="503" mass="55467" checksum="475E391377758D8A" modified="2013-11-13" version="1">MIRCIHRLTGTIPSPVGIKSQTAIPERSIGSDMAGLDQTDEIVYEPDTEFREQSNVAAFMNAHGIDNFEQLHRRSTTAVDDVAASGLDWFWDAAVEHMGLSFDEPYDQVRDASDGPQFTDWYVGGKLNIAHNTLDRHAAPDADARDRVACIWEGEPHEGAAVDSPTARDPAAGPTELRRVTYEDLHRQANRVANALTERDVGVGDTVGLYMPMVPEIISILYGCFKVGAIAVPIFSGFGVDATATRIADASCSVLFTADGFYRRGEAIDLKPDADAAIDRAGQVEHTIVYDRLGAELSWSARDEPWSEAVAAQSATYETRSLPADQESMLLYSSGTTGEPKGIVHTHAGGLVQPAKEIYFSFDHQPADRFFWVSDIGWMMGPWALIGTHAFGGTVFMYEGAPDYPTPDRFWEMIDRHDLSVFGVSPTAIRALRKEGEEWLAPHDLSSLRLLGSTGEPWDPESWLWFHEQVGNGEPXXXXXXXASRSSTAASKDIWSRAPRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ65</accession>
    <name>U1MZ65_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01641</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89480">
        <property type="protein sequence ID" value="ERG89480"/>
        <property type="gene ID" value="J07HX5_01641"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802060_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="6793" checksum="338DE7B350A863AE" modified="2013-11-13" version="1">MYAELDGLPNATDCGCPESLSGLPATGVTRISGRARTLACGYKTATLSSAVTAASTLATPTSSRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZC7</accession>
    <name>U1MZC7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01546</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89388">
        <property type="protein sequence ID" value="ERG89388"/>
        <property type="gene ID" value="J07HX5_01546"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="137"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="240" mass="26836" checksum="9BF0D3CA6DB55503" modified="2013-11-13" version="1" fragment="single">MVKKSSILHVDDKPSMRDLTETFLERIEEQFTVETATSAEAGLQRIDDRVPDCVVSDYDMPGMDGLAFLQAVREQYPDLPFILFTGEGSETVASDAIAAGVTDYLQKNQGPEQYELLANRIHNAVDARQEAKRAGRQERFTTRVLDTLEDVFYVLNKNGSLRRWNSRLAELTGYSEPELAEMQATGLFPDDEHENVVDAIETVLTTGEVTVRANLLTADGDRLPHEFRGAHLTDEDGEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZE9</accession>
    <name>U1MZE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01751</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89585">
        <property type="protein sequence ID" value="ERG89585"/>
        <property type="gene ID" value="J07HX5_01751"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_654894_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="419" mass="43182" checksum="FECBC02F64641011" modified="2013-11-13" version="1">MNRLLQFVAVFAVGFVLAGGAVLAAGAVGTSGDQPLSSESDADTDYWSAPDTSLESAQPSGNINVETSVDNATVVVHAPPSFRGLGSRGFVAPTSDISVSREVGPLITALTTAEQTVQIYSGDGRSGPGLASALSNADGFVTTAPESLSAEDRTAVTDFVDSGGHAVIGADPGSAGSISGLTSAMDTAVEPGFLYNMDTNDINYLNVFVEPSARADTNLTAGVDRAVFRGTTSVEPSSGMPGMTTVGDTERSITGQTGQFGVAAMTDNAVILGDSGFMSPEFATRADNNVLIGNLGEFLVADANEPAPQTNVSVNETAVIDAAQAYYEALDAGNVDAAEAAVHSNGEVTVPETFSDAVKNASIELRSPTVTETREGQAFVEGEQVTDPVDGELTTIPVRIELQREDGEWAVWARTIQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZI2</accession>
    <name>U1MZI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01612</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89453">
        <property type="protein sequence ID" value="ERG89453"/>
        <property type="gene ID" value="J07HX5_01612"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783892_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7283" checksum="F1498F92E27015E2" modified="2013-11-13" version="1">MSRAVDSGANHTKLPDRIALLVFWVGFIVWAGVFAPFDLSSLDGGLAGGLAVVFVMLTIDSCIDSKQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZM8</accession>
    <name>U1MZM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01668</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89503">
        <property type="protein sequence ID" value="ERG89503"/>
        <property type="gene ID" value="J07HX5_01668"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075182_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="52" mass="5364" checksum="9EFB04715F430627" modified="2013-11-13" version="1">MDRSAGTNTRTSAVSVKIGGSTLPXXXXXXXEQTATTADSDEDAVVVEAETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZP8</accession>
    <name>U1MZP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01693</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89528">
        <property type="protein sequence ID" value="ERG89528"/>
        <property type="gene ID" value="J07HX5_01693"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_175997_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="106" mass="11756" checksum="7858E9A31F9A29AE" modified="2013-11-13" version="1">MSERLVVEAGDKTAEELLTALHDGRRIIVQTEFLDADHEVVLRYDGEIYYCDTPTRLHKHDSVGEMRTCLTNRGYGRPAEEHPAGDSPDAGDEPAPVDSDTNSAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZQ2</accession>
    <name>U1MZQ2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01698</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89533">
        <property type="protein sequence ID" value="ERG89533"/>
        <property type="gene ID" value="J07HX5_01698"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_607812_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="37"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="207"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="450" mass="48641" checksum="195E1BD6D25EC348" modified="2013-11-13" version="1">MPDTELPVELPEFVQTTGNPLDAATEWKQTVCPDCGGPAERETDTMDTFVDSSWYFLRYVSPGLETAPFDAERGSDWLPVDHYVGGIEHATMHLIYARFFTKVLEDIDLLNGVREPFARLLTQGMVRKDGEAMSSSTGNVVSPEPFVEEYGADTARHFMLAAAQPEKAFDWTDDGVQSSYSFLRGLYELADALPVGAERSDPPAEHVTRETAATVAAATTEFEQFRFNHALQAIEELVSLLRRYAGADANTGADAGADRAPTPDQATLTAGVSAAVRLVAPIAPHVAEEAWTALGRDGLVAEADWPTAEPPASYELERQLIADTRADVREIIDVAGLRNPDSITIAVAPTWKHRARNIATETEENVVGAVMSDSGLRDRGEAAAEYAKELAAADYLDTVLEPAHEQAALERAAWLLEREFDATVTVCAKADAPALAADAVPGRPAIDIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZV1</accession>
    <name>U1MZV1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01754</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89588">
        <property type="protein sequence ID" value="ERG89588"/>
        <property type="gene ID" value="J07HX5_01754"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030778_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="612" mass="69223" checksum="C7497E789899475D" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N056</accession>
    <name>U1N056_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01870</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89698">
        <property type="protein sequence ID" value="ERG89698"/>
        <property type="gene ID" value="J07HX5_01870"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="42"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="236"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="322" mass="34867" checksum="CCFCA2DC0CB9E59D" modified="2013-11-13" version="1">MEMDHATAGSLADRTVATLNKVVIADRSFFETVLAGIVAQGHILLEDVPGTGKTLTARSFAEALGLSFQRIQFTPDLLPADITGSTIYNEGTGAFEFAAGPVFANVVLADEINRAPPKTQAALLEAMGERQVTVDGKRHALPRPFFVIATQNPIEQEGTFGLPEAQRDRFMIKTSIGYPDASGERRLIDRRADRTTQMPAVETVLEPDRVKTLQQVPERVEADPRLRDYLVALGRQTRADNRVDIGVSPRGVQRLFEAARALATIRGREYMIPDDIKRIAPSVLTHRIALTGDAAVAGASRSGVVTDVLNEVEVPAVSGTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N058</accession>
    <name>U1N058_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02007</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89835">
        <property type="protein sequence ID" value="ERG89835"/>
        <property type="gene ID" value="J07HX5_02007"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079334_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="311" mass="34479" checksum="522DB692AE5A8E98" modified="2013-11-13" version="1">MFSDTIYLPLVASTVYMRVLMTGASGTVGSALLKQLGDREEYEYEFTCLDLAPNDHPEHDTVAADITDLETLREHVAGHDAVVHLAAAVDLSSDWETILQANIVGTYNVLQAAAAAEVETVVFASSIHTVGLFEIEHSPAIYDPEHELTVTRETPVRPDSLYGLSKVFGEAAGRFFVENQPNPLSEALPTYAVNSRAYPTSFYSVRIKTVLDEQYDHPYGLAEMGVDGGYFSRGSDAYELLADRLKCTWLSHRDLAQLIDRCLQDETVEYDTFWGVSDNDGTWVDLTHTRRFSDTTLPTTARRGLALPSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0F6</accession>
    <name>U1N0F6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD synthase</fullName>
            <ecNumber evidence="3">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">FMN adenylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Flavin adenine dinucleotide synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ribL</name>
        <name evidence="5" type="ORF">J07HX5_02098</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal FAD synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89925">
        <property type="protein sequence ID" value="ERG89925"/>
        <property type="gene ID" value="J07HX5_02098"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034585_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046444">
        <property type="term" value="P:FMN metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02115">
        <property type="entry name" value="FAD_synth_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024902">
        <property type="entry name" value="FAD_synth_RibL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1 3" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="4">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="15438" checksum="9BD4101A8F02558E" modified="2013-11-13" version="1">MTRAVALGTFDLLHPGHVHYLEEAAATATELHVIVARAANVTHKPTPVVPDRQRVAMVAALGPVDHARLGHPDDYLVPIREIDPSVIVLGYDQHHDVDGVATQMAEAGIDTDVRRASERPREHGAELLSSGSIVSRILEQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0F9</accession>
    <name>U1N0F9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02103</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89930">
        <property type="protein sequence ID" value="ERG89930"/>
        <property type="gene ID" value="J07HX5_02103"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2748011_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7174" checksum="B4E847AE81DC1F0D" modified="2013-11-13" version="1">MLGCIQFVGLGATLTAISVAPSATQALILFKSNIILVVLVSTTRLREGHRLRRTLGAAVIAAGTVLAVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0R4</accession>
    <name>U1N0R4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02076</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89903">
        <property type="protein sequence ID" value="ERG89903"/>
        <property type="gene ID" value="J07HX5_02076"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1762541_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="15748" checksum="54EAAC23D894A803" modified="2013-11-13" version="1" fragment="single">MTSYTRRGALMMIAGGCLYWAVGTDAFDSAEVDRSVDIGTAQGASALLNINPADIDSNKVFDVSTEPHEIVVTNQTDSQLEITVESQNNQSNYRFGTNPNDVNSDSITVPLSPGEKTSQSSNGIFISTDETGTITEAIKFNADSQTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0V0</accession>
    <name>U1N0V0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carbon starvation protein, putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_02116</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89943">
        <property type="protein sequence ID" value="ERG89943"/>
        <property type="gene ID" value="J07HX5_02116"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_576869_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025299">
        <property type="entry name" value="CstA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003706">
        <property type="entry name" value="CstA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02554">
        <property type="entry name" value="CstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13722">
        <property type="entry name" value="CstA_5TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="8">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="CstA_5TM" evidence="9">
        <location>
            <begin position="287"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="473" mass="48922" checksum="0BF46B54ADB04211" modified="2013-11-13" version="1" fragment="single">AVFALVVGVVFNVFPATATASFFYIGMALLFGVYLYQFNLPFVPGAVTFVGLVFAGVFVGLEFPVRMVADNPSASDSIVLLGETSNWNWLPLSGAQGPNVAAWIPVIITYAFIASVLPVWTLLQPRDFLTSSLLYVGVGGMLLGVLVAAVTGLLGGGFSLEFANPGGGGTITKSDLQIEMDAWKGFTSALGPIFPFLFVTIACGTISGFHSLVSSGTTAKQLDKETDARAIGYGSMLAEGLLATTAVAALALVATASASSAGIVNALGNFPAGGAIMLGAGFGIPTDIGATFIGLVFVSFLLTSTDTATRLGRYMLEEIVGTPETSTQNLAVNRYFSSGLLLCVPAYALVGSGEWGTLWPLFGGANQTLAALALLSATLWLANWDDSKQLISTGVPMAIMLTVTVTALLWIGLYRAPTDLLDATGTSAQVSAGIQSVVALVLAGLALAITYMGYKNISEVRDDYTGGAVTSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P330</accession>
    <name>U1P330_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00018</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87877">
        <property type="protein sequence ID" value="ERG87877"/>
        <property type="gene ID" value="J07HX5_00018"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_751434_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="256"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="368" mass="38489" checksum="D74314A87F9C050C" modified="2013-11-13" version="1">MWQDTPELATILTAGLQLQLSGAIIVSGLAGVLAGGTAVWLVYTHAYLHTDGGAGQLNADLLWPFVAVAVVIALGAVGLPVAGGQLSASLLSVVPLVTFLLVFVPWNTFAFRYAGRGTLLTRRRIIGMSVPVTVLLLVYGSVAVGVVQPSQESYSTILLAASTLLLALVAVTFVSSGLVLTEAYRHGSIPFASGVIIVAPIAVLVIGIQVVSLSGFLTRELLAGLHLLVAAGVLPVAVGRYDVLATRPGTTTLGERTVVQDLNEPVLVSDRDGRIILSNQQAERLFGDDLSGRDLEGVVGTALTALREASTIACWTELGYKRFDPRVSAVTGGRDRRLGQTVTLIDXXXXXXXVGGRHAASRTRVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P361</accession>
    <name>U1P361_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00063</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87922">
        <property type="protein sequence ID" value="ERG87922"/>
        <property type="gene ID" value="J07HX5_00063"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043736_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CYCLIN" evidence="5">
        <location>
            <begin position="67"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CYCLIN" evidence="5">
        <location>
            <begin position="161"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="248" mass="27825" checksum="6FF67F487E268F0F" modified="2013-11-13" version="1" fragment="single">KKSRVGAPTTKTMHDKGLTTTIDWKDKDAYGRSISSKKRSQMHRLRKWQERIRTKDAGERNLQFALSETDRMASALGVPRSVREVASVIYRRALTEDLIRGRSIEGVATAALYAACRKEGIPRSLEEISDVSRVERKEIGRTYRYISQELGLEMEPVNPKKYVPRFCSELELSEEVQSKAAEIIGTTAEKGLLSGKSPTGYAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQEQIEAMGIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3A7</accession>
    <name>U1P3A7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00118</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87977">
        <property type="protein sequence ID" value="ERG87977"/>
        <property type="gene ID" value="J07HX5_00118"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147800_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12507" checksum="4CF81B1F29A6740C" modified="2013-11-13" version="1">MGGSVLAGTVGFIAAESVGFPIVGVVLYWAGFAGFLAVWQGKSVTLFDERDCALERRAMYIAINSFALGIILLWPTMVVVSELNVYTPPPVFDGVLLAIAVQSGLFAVAYGWLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3H4</accession>
    <name>U1P3H4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00193</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88052">
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        <property type="gene ID" value="J07HX5_00193"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017344_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="PTHR19248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="134" mass="14688" checksum="DA928948729DA5A8" modified="2013-11-13" version="1">MIGQQLTDCSGGERQRVAIVACLSQGIDLSLLDKLSAHLNVEQWVLAMSTIRRYADANNATALVSDHDTSMTEIQSDRVIIFDDTPVEAGRVAAPQGIRHGANAFLLISGITSRRDEPTNRSQLNKLESQLNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3R4</accession>
    <name>U1P3R4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="8">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpA</name>
        <name evidence="10" type="ORF">J07HX5_00295</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 8">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88152">
        <property type="protein sequence ID" value="ERG88152"/>
        <property type="gene ID" value="J07HX5_00295"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="28243" checksum="B777957154023B1A" modified="2013-11-13" version="1">MSLTAAFDEPAFLPYLVAGDPSYEASLAYVEALAEGGADAIELGLPFSEPIAEGPTIQAGIVRSLDAGMTPDRYLGFVRELAVDVPIVCMTYYNLLYQYGDTQGPRSFVTAAARAGIDGIIVPDLPAEEAEPLRTACDAFGLDLIFIVAPTTKGDRLTRIREQGSGYVYVQARLGTTGAREDVSDRTAASLARIDHWPLPKAVGFGIKTGNHAERIVRAGADGVIVGSALVDIVADGADKNDDSPVVADRLATKATELKRGALAGRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3U9</accession>
    <name>U1P3U9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00335</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88192">
        <property type="protein sequence ID" value="ERG88192"/>
        <property type="gene ID" value="J07HX5_00335"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165166_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="11792" checksum="C86C77DF69CE25FC" modified="2013-11-13" version="1">MNHTDAWLGAVGRASTVQPAVTDTLVLTITLTDPDGSTLTYRQAAATQRIPGGVELVWPPDRSVCPLVTDCGTAGTYIPNDEDAHRDAVRFETQLLPAETDTTTDQPPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P421</accession>
    <name>U1P421_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00400</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88257">
        <property type="protein sequence ID" value="ERG88257"/>
        <property type="gene ID" value="J07HX5_00400"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119850_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043832">
        <property type="entry name" value="DUF5809"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19125">
        <property type="entry name" value="DUF5809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15248" checksum="5C566AC00D4CDEBC" modified="2013-11-13" version="1">MKTKGVFAPESSTAAQRRYADLETAVEATIKAAGREQAATGAEYDTLITDAALATAHDALFAALLEVQVGARTAFENWRAWTAHEVTVVGAEGVDNIAWHAPAFADQAVALTFQDERAAAVGTLRRQAFGRLYRPLLETGAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4F5</accession>
    <name>U1P4F5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00511</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88367">
        <property type="protein sequence ID" value="ERG88367"/>
        <property type="gene ID" value="J07HX5_00511"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_781909_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="355" mass="37793" checksum="34F31BBCE40E085C" modified="2013-11-13" version="1" fragment="single">MSADTRGRLRLVALVGLLVVGLGATVAAGFVIADDQRSGEEVLSDVQEKYNNAESISADTVVTVESESGTTTANIGVAAAGEEQVRLNISDDDRYLVAGTDGEATWVFDPTTELTGVIQETADGSAMISLRSGTDEPTSGLSALLPSDISSETTVGELRDQFGGELPAAFDDIDDATTLDELPDELDGNVSSALPESFEPEDFDSSGFNISEFDINEFNVSEFDFESVDLDEFDTEALPSTFNETAVEEFIDELESAAEDGTFDGAFEDEGVALNETTIDEARATINDALPDEIDNLESYESLDALTDDLAVVANKTTVERTGTTSINGVEANELLITHPDLPGETRLYTSVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4G9</accession>
    <name>U1P4G9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00532</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88387">
        <property type="protein sequence ID" value="ERG88387"/>
        <property type="gene ID" value="J07HX5_00532"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_641944_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="19"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="432" mass="44392" checksum="97622CB042F223ED" modified="2013-11-13" version="1">MTWALRTRVSERFGENTPVVGTVITSTFLIGFGGGVVFPILPNLGTILDISPLMVAIILSANRATRLVVSAPAGALVDRLGTRLPFVVGMGVQTIGTAGYVLAFYLPVPTVWFISARVTWGIGSAFVFATALTIAADVSTGDSRGASMGIIRGGVLFGFPTGVALGGLVSEYAGNVAAFGLATAFAAVATVVAYRLIPETHVTGDTHRSIKPWDIDTSLSALTVGGVNFVVLFIYVGALFSTLVVFLDQKGLSVFGLGPQGSSGVFMAITVVAAALFTILGGSLSDRRESRMPTLLVFLGLAGGGFFLLVAVESVLVLAVACVFIGVGQGGMSGPLLALLADLTPNEQMGRAVGTNNVFGDIGGSLGPLVTLPLVDRIGFDPVYLACGLLPFAAAVALTVGVYAETGRLLPSQTAADSVARREQPSDSGTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4J0</accession>
    <name>U1P4J0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00562</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88417">
        <property type="protein sequence ID" value="ERG88417"/>
        <property type="gene ID" value="J07HX5_00562"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121763_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14129" checksum="D67EA134E0F83DA0" modified="2013-11-13" version="1">MALRDAVESDADRLAGLADTPTDVMRNLVHDRTVRVLERDGETAGFVSYDAQDQTIHITQIEGQPEDIETLLAEPVRFAREEEMTVELLIPEPDSATEEAASAAGFEIVGRGPTFDGEPTRRFRTEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4R7</accession>
    <name>U1P4R7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00663</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88517">
        <property type="protein sequence ID" value="ERG88517"/>
        <property type="gene ID" value="J07HX5_00663"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2230317_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043867">
        <property type="entry name" value="DUF5827"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19145">
        <property type="entry name" value="DUF5827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="10118" checksum="F0A8875C8D28B121" modified="2013-11-13" version="1">MPIDRGAVETLRPLEFRAPADVLTGDKLYTVYEIARLLQGVDPEADLDPATEDILLDWAIPWMVTHADAFVFAEPEADDQPGYYGLAAAPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4S2</accession>
    <name>U1P4S2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome subunit P45 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00668</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88522">
        <property type="protein sequence ID" value="ERG88522"/>
        <property type="gene ID" value="J07HX5_00668"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005937">
        <property type="entry name" value="26S_Psome_P45-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01242">
        <property type="entry name" value="26Sp45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="184"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="406" mass="44418" checksum="CF434B6203DCA142" modified="2013-11-13" version="1">MSRSPSLPERPRLNLDPDLSPAERLDALERHFADVITVNETLNEQLSSAQGRQQRLLENVDKLQRENETLKSSSLYVATAEELLDDGVVVKQHGNNQEVLTDVSPSIRAELEPGDRVAIDDSFDVKQILDPETDARAQAMEIDTSPSVSYDEIGGLAAQTREVREAVEQPLINADQFNAVGVDPPSGVLLHGPPGTGKTMLAKAVANQTDATFIKMAGSELVQKFIGEGARLVRDLFELASEREPAVIFIDEIDAIAARRTESKTSGDAEVQRTMMQLLSEMDGFDDRGEIRIIAATNRFDMLDQAILRPGRFDRLIEVPLPDWDARQRIIEIHTSEMNLADVVDLAALASKTDGFTGAELASLATEAGMFAIRDDRTVVQMSDFDSALDKVAEDDSSTGTPIAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4W3</accession>
    <name>U1P4W3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD superfamily phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00713</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88567">
        <property type="protein sequence ID" value="ERG88567"/>
        <property type="gene ID" value="J07HX5_00713"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1464114_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="77"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="185" mass="20368" checksum="E445BC3221AD7AB9" modified="2013-11-13" version="1" fragment="single">MLFIVSNGLNGSDPVAEPFTHQAVSSHMTTIKDSVHDHIEVTGVARDLLDTPPVQRLRRIKQLGMAVLVYPSANHTRFEHSLGVYHLADRALNQLGVEGRTAKRVRAAALLHDIGHPPYSHNIEALLHRKTGKYHDEVHDLLRSGQVAEVLADHELAPRRVADLIAGEGRLGALVSGELDVDRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4Y9</accession>
    <name>U1P4Y9_9EURY</name>
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        <submittedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00743</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88597">
        <property type="protein sequence ID" value="ERG88597"/>
        <property type="gene ID" value="J07HX5_00743"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="2">
        <location>
            <begin position="113"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="248"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="35970" checksum="89FCA4DE5C0ABA3D" modified="2013-11-13" version="1">MTEVGLTGYGRYLPDRVVTGAEIAAESGIPEWVVTEKMGLVEKHVCPPDEEHVTDMSVRAGKRALADAGVEPAALDLLVYHGSEYKEYIVWSAAANIAERLGADNAYATESYALCAGTPIALREAAAQLQTDSPDTALLVGASREEDLIEYGDTDASFAFNFGSGAAASVLEVAPDEPRALVRESHAVTDGSFSEDVVVPAGGSRAPPSAETVAAGQHTLTVPDPEGMKERLGAVSLPNYLEVADTALNRSGYDRSAIDFVAVTHMKRSFHETLLAELGLDPATDGYYLDEYGHVQSADQLLALHEGVEDGRIEAGDLVLFLAAGTGYTWSATVLEWHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4Z3</accession>
    <name>U1P4Z3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00748</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88602">
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        <property type="gene ID" value="J07HX5_00748"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2150938_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="11721" checksum="9AD978407EB3C1F4" modified="2013-11-13" version="1" fragment="single">MTGFALVAAIIGGLKTLAGPLFGYLFLEWVEEFLATKSNGGGLQPFLQTILPDGVLDATISGGLTVDRALESFMTGHGEFYAGIIFVAFVLFIPIGLLGTLRLAVGERSIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P513</accession>
    <name>U1P513_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00773</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88627">
        <property type="protein sequence ID" value="ERG88627"/>
        <property type="gene ID" value="J07HX5_00773"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036918_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="PTHR13353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="446" mass="44892" checksum="917DA17801334FD5" modified="2013-11-13" version="1">MTSGVRRAAAFALVGTVTFVVPWIQSVREPAVATLAAAGPFLLLAAAALTVGPRSRVFELLARPSDRHDGRLYGVASFLLAAAGLAILSVSFGLPAHVFVATVVLLSVGTLGDQLVRTVTAEHTLAAAGFVVAGFVGATGAQLVAGWLAGSAISWQLVVFLAASGSLSAALLREALFRGDDALALVAVALVLWLLAWLPLEITALRITVGIGATVVLGYLSVALKTASLRGMLTGVWLGLLAIVVGDYAWFAVLVTFFGIGGLSSKYRYDTKVRRGIAQENKGVRGSGNVLANSLVALVAVLAAAASPEIPGTQTVYLFAFAGAVSGALADTLSSEVGALYDSPRLITTLEPVEPGTDGAVTWQGELAGIGGAAIIAGIAAVGFEPIGAVGAGVVIAAGFVGITVDSALGATVEGGWLGNEGVNLIATFVAAITGSSLSAAVFNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5D4</accession>
    <name>U1P5D4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00898</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88752">
        <property type="protein sequence ID" value="ERG88752"/>
        <property type="gene ID" value="J07HX5_00898"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3393271_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="32" mass="3450" checksum="CFCA90C72813F561" modified="2013-11-13" version="1" fragment="single">MNTWELAGSLNGVWFSELTRFPPAVNGGTPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5U0</accession>
    <name>U1P5U0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01028</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88882">
        <property type="protein sequence ID" value="ERG88882"/>
        <property type="gene ID" value="J07HX5_01028"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_184177_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7286" checksum="A721E97349598A1E" modified="2013-11-13" version="1">MATEQCDGCKKAVNIGGGIADIWTLDTGPTEGLTLELVDGTEHFLCYDCIDRLPDDREVTATDVAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5X6</accession>
    <name>U1P5X6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01084</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88937">
        <property type="protein sequence ID" value="ERG88937"/>
        <property type="gene ID" value="J07HX5_01084"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_989035_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="281" mass="29674" checksum="FD49B66A5B27F8E8" modified="2013-11-13" version="1">MSLRVDADRLRADIEATAAFGAVETDAPDARGRTNRTGFEANRRARDYFVERLRDAGLSVTVDPDTPAVAAGSHLDSVPDGGIFDGLLGVYATLEAVRGMQAADHTPDRPITVVSFTEEEGATFGNGLLDSSVATGTTALEAARARSDTTGRTLGDALDQIGYAGDGRIAPNGGPAFSSSTSNRTQHSSRPVQTSASSRPSPALPAVRRPSPARQTMPARRRWALGSTRSRPPRLCAMSNRLRRLPPNSLTPRPSALSAPSAPCRSSLGRQTSFRPVSLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5Z8</accession>
    <name>U1P5Z8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-binding protein J07HX5_01117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01117</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PDCD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88967">
        <property type="protein sequence ID" value="ERG88967"/>
        <property type="gene ID" value="J07HX5_01117"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122978_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00026">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022889">
        <property type="entry name" value="DNA_bind_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PTHR10840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="SSF46950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="13260" checksum="DD96C303923D9089" modified="2013-11-13" version="1">MSGDQSDEELEQLRQERMEQLKDQAEQDDGGQGGQGQQQQAEAQKQALLRQHLTDGARKRLNTVKMSKPEVGEQVERQVVALAQSGRIRDTIDEQKMKQLLQEITPDSKSFDIKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6A1</accession>
    <name>U1P6A1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01239</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89087">
        <property type="protein sequence ID" value="ERG89087"/>
        <property type="gene ID" value="J07HX5_01239"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949143_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="7095" checksum="3C33658309954E4B" modified="2013-11-13" version="1">MILSMHERIRIDSTRGLARISTVRMPTLSWCQLIKRFVCQLYLPFEYESIEDLNSFETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6L6</accession>
    <name>U1P6L6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01372</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89217">
        <property type="protein sequence ID" value="ERG89217"/>
        <property type="gene ID" value="J07HX5_01372"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068050_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="28413" checksum="A8D6AC429BDDC110" modified="2013-11-13" version="1">MALRNTVQTSFVAGLVLIAPLVVTLYLFQLLVGTLLSAVDPVVQESNLEQYTAELIAQAIAVVSVATAIVLIGFLAQRKHGQRLFGSLGRLIAVVPVIRTVYATVRQISSSFTSGETAYDSLVLVEFPRRGVYAVGLVTSESPTAVVDVAEEPVRNVFLPSSPNPAGGRLLFVPESQIHEVDLSVREGLGLLMTTGAGSDQTATLPPSPVELSPAKAVSTVETPTSEPASGTQSQKATADTTAADDDPTAEPETNADKTEANDPSAGGRSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P726</accession>
    <name>U1P726_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00057</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87916">
        <property type="protein sequence ID" value="ERG87916"/>
        <property type="gene ID" value="J07HX5_00057"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3018541_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="56" mass="5987" checksum="BD79C8458BA7C40B" modified="2013-11-13" version="1" fragment="single">MTRRQFFGSLCAMVFLVNMARLVFAPLIQPVAEEFQITAASLGVVTSAAWIGSAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7L3</accession>
    <name>U1P7L3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase propeptide and YPEB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01713</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89547">
        <property type="protein sequence ID" value="ERG89547"/>
        <property type="gene ID" value="J07HX5_01713"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2103568_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PepSY" evidence="2">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="14014" checksum="C79D55B44813E046" modified="2013-11-13" version="1">MNFNRHTVLGVIGVIALGLLAMSGSGLALGQGSMSSVLDDGDDDDTIAAENVSLSEQEAIDIATAETNGTVEELELESEDGTPVYEVELITADGTETEVAVHANDGTVLETESDDEADEMDDDESDEMDDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7M2</accession>
    <name>U1P7M2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01723</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89557">
        <property type="protein sequence ID" value="ERG89557"/>
        <property type="gene ID" value="J07HX5_01723"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2176188_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002837">
        <property type="entry name" value="DUF123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37460">
        <property type="entry name" value="PTHR37460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01986">
        <property type="entry name" value="DUF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="12041" checksum="CC98DFC872BD915D" modified="2013-11-13" version="1" fragment="single">FARVDRHRELARGERETRHWHVDYLLGHPETEITRVVQTGDGADIECAVSQAVAADHDPIAFFGASDCACGSHLAYAPDGETLITTVERAHKRLSPPAEHDSQEEVPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7R1</accession>
    <name>U1P7R1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1611_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00324</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88181">
        <property type="protein sequence ID" value="ERG88181"/>
        <property type="gene ID" value="J07HX5_00324"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1707859_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035402">
        <property type="entry name" value="DUF1611-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011669">
        <property type="entry name" value="UCP026760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40690">
        <property type="entry name" value="PTHR40690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17396">
        <property type="entry name" value="DUF1611_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1611_N" evidence="1">
        <location>
            <begin position="48"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="154" mass="15559" checksum="55179B77FA7933F9" modified="2013-11-13" version="1" fragment="single">MDLRAAFDVPTPAIVLAEGAFGEPGGKTAHGVALHSELFDAAAVVDSTRANTTAGDVLDAPTVADVPVVATMAEALDRAPSAEVLIIGVAPAGGTLPAAWVADIEAAVVAGCDVVSGLHVELSEDPQWQVAADEAGVELYDIRQPPAADKLRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7V7</accession>
    <name>U1P7V7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00374</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88231">
        <property type="protein sequence ID" value="ERG88231"/>
        <property type="gene ID" value="J07HX5_00374"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_827694_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="336" mass="36812" checksum="A115427680F6F7CA" modified="2013-11-13" version="1" fragment="single">MPRGLFIGSTTSEVVKLYNSAYRTTERARKTAAMLANRPADPLADGESTADTMSYVWPTARAFTSATADPDQFVGYLMPFLNLETRHEIQRHARRALDWRHSTDRERLQTAYNLAAAVGYIHKQGHAIGDMNHENIHVTPTGLVTLIDCDAFYITGTDGTVFQGQTEHPRYAPPEGVGGELDTVRQADRFGLAVHLFQLLMAGFHPFQGAGEHSTGGSLADQITAHRFPYPRPDRGVAPPPGAPAYRQLPPVVRSLFERAFVAGKHEPADRPDAVAWMERLQTVLTAPDNDPADSLETEARTETAALSVDVAAELAAVQELLPELSRADFFHSEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P811</accession>
    <name>U1P811_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01874</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89702">
        <property type="protein sequence ID" value="ERG89702"/>
        <property type="gene ID" value="J07HX5_01874"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145814_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="16858" checksum="BFD80314DD4BB0A1" modified="2013-11-13" version="1">MLFPTHLGVAYVTARRLGLSVPWTVLGAVLPDLVDKPLGRLGETDRYHSVAHSVVGVCLTLGVSNRTRIARSVWAGWATHLGADAAGMAVNGRYRDLAFLLWPVARERRYSEMPADLVLPGTRSYFQSPAFVLELTVWLTAAQTAASRSSGEHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P822</accession>
    <name>U1P822_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">proC</name>
        <name evidence="5" type="ORF">J07HX5_01884</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89712">
        <property type="protein sequence ID" value="ERG89712"/>
        <property type="gene ID" value="J07HX5_01884"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_3_1_2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="3">
        <location>
            <begin position="5"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="4">
        <location>
            <begin position="146"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="26562" checksum="B42E67D5C84E81B5" modified="2013-11-13" version="1">MAHLSVVGCGNMGGALLKGLAQSGNHRLVGCDVDEHARAAVAECCVETTDDLAVAGQAEYVVLALKPDVVTDILSALDLNSNQTVISIAAGVSTDHLATVTDASIVRLMPNLAAETTNMAAAVTGAVDDTTRALLDDLGEFAEIKEPQMDIATAVNGSGPAFIFYLIGAMKRAGVNSGLDDTQAETLAAQTAKGAAETVLQSEQSIDELIDSVCSPGGTTIEGMRQLWESTAESDLITAVHAAEDRSREMAAEVTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P832</accession>
    <name>U1P832_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00444</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88301">
        <property type="protein sequence ID" value="ERG88301"/>
        <property type="gene ID" value="J07HX5_00444"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="31611" checksum="2EC30E2CE51A2A16" modified="2013-11-13" version="1">MIDETTAEIAEMRTHSSSVVAVRAAEALGELTDREFPAVGEFLRAVERNSAALRRANPSHASLQTTQQEIVETVTDAGGEMVETVAAAKDRLQTAIETVIDRIKTSKQAAAVAAAELLADGTTILTHDYSTTVLAAIEQAHSDGTSLTVYVTEARPRYLGRKTARRLAELDDVDTRLVVDSAAGECLSTCDQMVIGMDCIADGHVYNRVGTYPIAATAADRGVPVTVVGAATKLVSTGFSFENDHRAATEVMREPADGFAIENPAYDATPIGLVETVVTDDGTVDPAELAEQDATTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P833</accession>
    <name>U1P833_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, CopG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01894</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89722">
        <property type="protein sequence ID" value="ERG89722"/>
        <property type="gene ID" value="J07HX5_01894"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197235_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="7588" checksum="35795E22B38BCBFA" modified="2013-11-13" version="1">MERVTLRIPRQQVEEVEQMVDSGEFPNRSEAIRSAVREMLAEQDTEQDRPSEDRGREDRSWARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P845</accession>
    <name>U1P845_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01904</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphosulfolactate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89732">
        <property type="protein sequence ID" value="ERG89732"/>
        <property type="gene ID" value="J07HX5_01904"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062679_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003830">
        <property type="entry name" value="ComA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036112">
        <property type="entry name" value="ComA_synth_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02679">
        <property type="entry name" value="ComA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102110">
        <property type="entry name" value="SSF102110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="279" mass="31177" checksum="53C7AE33CE7F87F8" modified="2013-11-13" version="1">MADPDRPFEFLHVNERESKPRSTGITEIRGPYYDPMGPRELRDILDTMGHYVDIYKFSGGSFALMPEGVVTELIDICHDHNVKVSTGGYVENVLARDNDSVEQYFAEAERVGFDIVELSSGFLAIGVDDMVRMTEVVAGDYDLEPKPEINVQFGAGGATDPEVLEDQGQQDPEQAIKEGKRHLEAGADLLMVEAEGITEEVTEMRTDVAYQIANGLGIENLVFEAPGPEMFEWYLKNFGPEINLFVDNSQIVELETMRSGLWGKATTWGRTVTWKGDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P878</accession>
    <name>U1P878_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01934</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89762">
        <property type="protein sequence ID" value="ERG89762"/>
        <property type="gene ID" value="J07HX5_01934"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1472043_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="183" mass="18777" checksum="5AFB3FBBC6D96647" modified="2013-11-13" version="1">MLSTVFHSQSNLWSPILIELGRAGCRCLCPFVCSILCAGVGAGPVKANGVEAGTASINYLTLPRSGLLAPHLSGSGVSWVCVGVCSQSGHSGSRLHRRLSFAGGSECPSLTDQALSHTNGARFLSQLDVVGDTVSLVGHSLTARVSTLAESAQVTRAGAVSSLLAPSTLAKRDGAVNYNFDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8N6</accession>
    <name>U1P8N6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00641</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88496">
        <property type="protein sequence ID" value="ERG88496"/>
        <property type="gene ID" value="J07HX5_00641"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154323_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="240" mass="28060" checksum="86F318E2AD5C0387" modified="2013-11-13" version="1">MVGVDINEDCVGLAAFTESEITDSFVLDFPGIKQERHRFFTMRKRMQTAGQTAFNDQCRNKEKRFVHDQLHKVSRLIVKWIHRLDRPIIVFENLKDMRDNIEYGTRMNRRLHSLPFAKLRDFITYKAAWNGIPSDDVDPAYTSQRCPRTECRHTVRSNRQKKRFKCQNCGFQDHSDRKASVCVVQEWFKKQYENVPALNTLPQVQKCELRRQASGSVDLPTVTQHNARDNQIEDVAGVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Q5</accession>
    <name>U1P8Q5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endonuclease III</fullName>
            <ecNumber evidence="9">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nth</name>
        <name evidence="11" type="ORF">J07HX5_02090</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="9"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89917">
        <property type="protein sequence ID" value="ERG89917"/>
        <property type="gene ID" value="J07HX5_02090"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_3_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="10">
        <location>
            <begin position="44"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="228" mass="25162" checksum="50040EA4DBD17B76" modified="2013-11-13" version="1">MGTPRAETSEQAAVVIDRLEETYPDATISLTYSNRLELLIAVILSAQCTDERVNATTQTLFEQYDDAADYATAGQDEIAGLIDSITYYNSKAEYITTACERIADEHDGAVPDTMAKLTDLHGVGRKTANVVLQHGHDIVDGIVVDTHAQRLSRRLGLTENQRPEAIEQALMELLPKDNWQSVTHLFIDHGRAVCTARNPDCGECVLEDICPSSKRDSDRDLASGEPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8Q6</accession>
    <name>U1P8Q6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00667</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88521">
        <property type="protein sequence ID" value="ERG88521"/>
        <property type="gene ID" value="J07HX5_00667"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1792049_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="144" mass="15717" checksum="284BA7FE51526447" modified="2013-11-13" version="1">MEVCSASLLSSVIKTVLSFLSRPVCDVNIANDLRVPVAWSVSLISVGGFAVGVFVIASMIYLFYQFNIQTVSIGEFQVPSSVIKATLLLFLISLVYGILVRRSVLAPMVLWTGVIETGALIFVVYLFYRLVMSLETIADNLESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8R2</accession>
    <name>U1P8R2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02100</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89927">
        <property type="protein sequence ID" value="ERG89927"/>
        <property type="gene ID" value="J07HX5_02100"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257440_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11508" checksum="2A7D8D04AD416808" modified="2013-11-13" version="1">MLQNSRGQSVDPVPFIVVTGMTFLWAYSFFPLYLQTLGVGVPIGLAVATLVFLPLAAFAYYRLVWNAQLEVQTEVSPALRFEQIMLQAVIVTGLCLVLTIVLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8T1</accession>
    <name>U1P8T1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02120</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89947">
        <property type="protein sequence ID" value="ERG89947"/>
        <property type="gene ID" value="J07HX5_02120"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1598958_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="166" mass="17842" checksum="6C1DEF65B7E4998E" modified="2013-11-13" version="1">MRPRHGTGPEWVITAGYHMLRRMSRRAVLSSVGAGGLAAAGCLMAETDPAPDLRNRPTVVVHQFYALAGESETDAAFTRAVEPILHSVSLLPSVLEGRSGHWRTARRSVVADIAIMAEDLTPDQVASRSSFSTPVVTDASSLLAEENVLTEATLDVSKISEFSIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P965</accession>
    <name>U1P965_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00822</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88676">
        <property type="protein sequence ID" value="ERG88676"/>
        <property type="gene ID" value="J07HX5_00822"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="226"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="450" mass="47267" checksum="926F1ADBCA0E62CD" modified="2013-11-13" version="1">MDATAYRDGLVALRRELHRRPEPAWCEYYTTARIVDELKQIGVDELHIGPDAIAADARQSVPDEETLTTWLGRARATDVDQAVLDQLTGGHTGVVAELAGDAPEQGPTVALRVDIDGLPREEATTADHTPVQEEFRSEHDGHMHACGHDAHAAIGVGVVKALSEASFPGRAKVIFQPAEEQIGGGPAIAQSGHLDDIDALLAVHVGLDHPTGEVVAGVDGFLAVTNLEATFRGEGAHAGGRPERGRNAVQAMATAVQNLYAIARHGDGATRINAGEVNGGSAGNVIPDTAHIVGEVRGETTALMNYTRDRAEQVLESAATMHECELSLEYGSEAPSAESDDQPREFVAAAADTNDRVETVLDSDALGGSEDASFLMQRVQDRGGVAAYVGVGTDHPGGHHTATFDVDETSILVGVEVLADALLAMARAEIDATAQSEHDGTPAGTPPEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA53</accession>
    <name>U1PA53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01136</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88986">
        <property type="protein sequence ID" value="ERG88986"/>
        <property type="gene ID" value="J07HX5_01136"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3302610_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4335" checksum="9A8DB1192AE2D4DC" modified="2013-11-13" version="1">MTVVVTVLLPLGSIRHTNATPIWLAGWPNARHAIPLFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAK9</accession>
    <name>U1PAK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01289</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89136">
        <property type="protein sequence ID" value="ERG89136"/>
        <property type="gene ID" value="J07HX5_01289"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2284941_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="101" mass="10825" checksum="7B39943E452FBA69" modified="2013-11-13" version="1">MATFHCNETMTDQTVTVSDKLLALPTEATAHEAAAIAAAVGASLQDERVAPTDSPTDADTARSRRDRFRFAGRTAAVTGIARRCPRCVPADXXXXXXXSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC36</accession>
    <name>U1PC36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01822</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89651">
        <property type="protein sequence ID" value="ERG89651"/>
        <property type="gene ID" value="J07HX5_01822"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_616241_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="444" mass="48770" checksum="51CCB11BB37EEAC6" modified="2013-11-13" version="1">MQNDWRPSDDTVVTTGRVLLLPADQGWTVSASNSGQSYWSDGRTNKNRSSCISLSPPDVPGRPLRGCLFVLFALVLLAFDAFCEVVDNHDITDCSYPAIRNDHTLSIAALLFEQLAVEIVQCEACHLLGVQIESEVLNFTEKNAVVRVDLSTDKICDLLWRSIAVHIYWFARRGVKCWLGRQTATARHTARTADTPSSLGGPVGPRRRNSVLTCQSRISGVQTDDCGRAVGDRQMPSTIIHLAFAGLLTAALLGREFDRWSLAVVLAVVAFPDLDSFIALVATPGHRTVFHNLWIPASGAVAVWLDTRIRDRSLLRDRWGRRGVRVAWVAVICYLFAHLGLDLVDGVINAFWPVYDQFYTLRGMLELSDQRGIVQTFVEWNGLVPVPQGIGTTGTVEITTGVDPGEASTERVFPVIGAGWELIILVTGTLVTAARLQTTDTTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCE2</accession>
    <name>U1PCE2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01933</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89761">
        <property type="protein sequence ID" value="ERG89761"/>
        <property type="gene ID" value="J07HX5_01933"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2177796_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="12401" checksum="A4B9126B9DC45696" modified="2013-11-13" version="1">MWVSLTVTRLPTEVSNTDKTAYYPQIKKLESDWDLQRKTTLHWMATHLAWVSRVDDTVCQLPTRNRVGLPVDSHVSCSTCGKPHAPRFPTRGFLRRLPTGKSGGLVHYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCE4</accession>
    <name>U1PCE4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L31e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl31e</name>
        <name evidence="6" type="ORF">J07HX5_01938</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ribosomal protein L31e family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89766">
        <property type="protein sequence ID" value="ERG89766"/>
        <property type="gene ID" value="J07HX5_01938"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112570_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00410">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_L31e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_L31e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="SSF54575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9741" checksum="6A5E5A959C78F029" modified="2013-11-13" version="1">MSADGFEERVVTVPLRDARTAPKSERADAAMSIVRDHLATQFSVSGSAVQLDASINEAVWANGRKNPPSSLRVRAARFEDDNVVEAELAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCW0</accession>
    <name>U1PCW0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02099</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89926">
        <property type="protein sequence ID" value="ERG89926"/>
        <property type="gene ID" value="J07HX5_02099"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3161269_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="48" mass="5101" checksum="46F0C1E00C1A3CF5" modified="2013-11-13" version="1" fragment="single">MSILRGGFKFVAGVADIVSSDGDIRVLLVLDLLLSLVFATAVLYGLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCZ0</accession>
    <name>U1PCZ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02134</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89961">
        <property type="protein sequence ID" value="ERG89961"/>
        <property type="gene ID" value="J07HX5_02134"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675469_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="409" mass="44502" checksum="D4FC289A58FC9638" modified="2013-11-13" version="1" fragment="single">DENDPAPEPTVGWQIDDPGQPQHVDDPDWRMHGHDTANSFRNQHAEGPSDDPSIQWTFNPGSSTLAYHPTIVDGTVYACGAVDPTEESDEDQTYRLVAIDGETGEVDTIVTDQNVIARPCIIGETVYVAIDGEVHAYDRVTGTKQWETNNGIILYDSYTIRQVGDILLATDGESLQFVNQDEPTHQLYAIDPDTGDVRWEAPGTGPNERLASGLPLATDTVAVFEATRPAWRLTDGTRAGTLPQLTEGESETNSRGSETLFGELLILVGYTANECVIVAHDWQTLEQRWCRTFPEDTDGSNPILLNGILWVPHMRTVFGLDPETGETRYKATPEMTPDDDNLDIQLIAGKTELYGVPHDGDGAFAVDPTNGNITWEIQTESVTGMRIGAGAVAGDLLVAHSGGKLFGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFS7</accession>
    <name>U1MFS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00155</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88014">
        <property type="protein sequence ID" value="ERG88014"/>
        <property type="gene ID" value="J07HX5_00155"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069060_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025510">
        <property type="entry name" value="DUF4397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14344">
        <property type="entry name" value="DUF4397"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4397" evidence="1">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4397" evidence="1">
        <location>
            <begin position="120"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="212" mass="21909" checksum="2B65C83678EC6B58" modified="2013-11-13" version="1">MHSLKPSQALFLFAMSNEAAVRVGHFSPDAPNVDVLVNDEVAFEDLAFEEVTEYAELPAGTHDVAVAPSGTEDAVLELTLDIEADTSYSAFATGEVGEESLQCSVFVDEPGDIADDQTHARLIHTSPDAPSVNVQVADGGPVLCEDIGFREASGYVPVDAGSYDLEVVPTGSSDPALSLPDTELAPGTAVSAVAVGKLEDGSLGALFAEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG32</accession>
    <name>U1MG32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00292</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88149">
        <property type="protein sequence ID" value="ERG88149"/>
        <property type="gene ID" value="J07HX5_00292"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092285_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="154" mass="16825" checksum="CC2D1A73C10A5E5F" modified="2013-11-13" version="1">MTDEQEDSGWARLLEEMERIATAAEDWETLTIPAGDAGAVGPGSRLADRHGFAYVIPGEEADRFAKLFDRGQFPETELYRRVTPPALYLLTVFKDPAAGTAIFLAGVLDRTEDGFAGCREAAEAAGQMYSHLFRVDGTHLGSFTHADPAPFFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG34</accession>
    <name>U1MG34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase elongation subunit, family B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00297</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88154">
        <property type="protein sequence ID" value="ERG88154"/>
        <property type="gene ID" value="J07HX5_00297"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430006_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
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        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="2">
        <location>
            <begin position="454"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="636" mass="70877" checksum="B006345DE57B3A21" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH55</accession>
    <name>U1MH55_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00765</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88619">
        <property type="protein sequence ID" value="ERG88619"/>
        <property type="gene ID" value="J07HX5_00765"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1492936_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19648" checksum="6EC5BCF01B02EC95" modified="2013-11-13" version="1">MGILKRTELLLWGVGAASAVGWWLSTPTTAVSDLLGLWGALVAGVAVVGYVSSGILYRNRVWQCWLGVSVVGLGLNFVLLEDLAPSLVRDQLFKLGYLYPWFLLIAVGYLFTTAYEFDNKELANRERAIAGSAGVVCVGLFLAFWTSRPADLSRLFRSLTGVSVVPTALLALSYRLRTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH58</accession>
    <name>U1MH58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00770</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88624">
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        <property type="gene ID" value="J07HX5_00770"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026231_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01458">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="133"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="461" mass="51649" checksum="A3B9CA00D3C11336" modified="2013-11-13" version="1" fragment="single">MSSDEIQETNTEARFEFKKEENSAFEAEKGLDEETIRVISEDKDEPEWMLERRLRSLRLFKEMPMPDWGPDLSEVDVDEIVPYIRPDIETRGGVEDWEDLPDEIQDTFDKLGIPEAEKEALSGVGAQYESEIVYQNMQEQWEEKGVVFCDMDEAVQEHEEKLREHFMTSAVPPSDNKFAALHGAIWSGGSFVYVPENTTVNMPVQAYFRMNSEGMGQFEHTLIIAEEGSEVHYIEGCSAPKYSEFNLHSGGVEVFVGENAHVQYSTVQNWSRSTYNLNTKRALVEREGTMEWVSGSMGSKVTMLYPSSVLKGPGATDNHITIAMAGEGQDIDTGAKVYHNAPRTSSAIESKSISKDGGRTNYRGLVHIADGAENSSTAVECDALMFDNDSTSDTMPYMEIQESLVDVAHEATVGKIGDEDVFYLQSRGLDDDDAKQMIVAGFIEPITEELPIEYAVELNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH87</accession>
    <name>U1MH87_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Preprotein translocase subunit SecF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00810</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88664">
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        <property type="gene ID" value="J07HX5_00810"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783890_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7553" checksum="61C15475555106E8" modified="2013-11-13" version="1">MRTGISMTITSIAAMVTMFVVSSPWVLGIPLLPDVALVLVFGLTADLMNTYLLNMSLLRWYKYEGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHD9</accession>
    <name>U1MHD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00875</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88729">
        <property type="protein sequence ID" value="ERG88729"/>
        <property type="gene ID" value="J07HX5_00875"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075179_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="52" mass="5698" checksum="2ACCED0F56256332" modified="2013-11-13" version="1">MSEIETQDVLEELASLPSLIAPSVSPDGDQIGIYYDVTGRNELHLLTPRQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIG5</accession>
    <name>U1MIG5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01343</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89189">
        <property type="protein sequence ID" value="ERG89189"/>
        <property type="gene ID" value="J07HX5_01343"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066582_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="277" mass="28652" checksum="0542114032832FF2" modified="2013-11-13" version="1">MNLAETAEQAARDAVVDVEPGQLRARLETRLAEEPLLPGALTVRVGTAPPRTAKTETGTETQAELKLKPELASRIDPDPGPESLVAQRAAGVQLVSVGLRWTRQLVTEAEWPVETETTPGGRPDAGAEPDPNAGSGPAADTGIDTTVALLGADVAVARGSSLLARTAAVDRAVAVVRTFGRTQTAATDSSDAGGRADSETCSRGQLEQDLLELAVIAGGTVGSEAVTPRLTDLAGELATTLTDETGAFRSPERLRSEVVAEQLRYAASQPDVGSPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIS1</accession>
    <name>U1MIS1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truD</name>
        <name evidence="6" type="ORF">J07HX5_01482</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89324">
        <property type="protein sequence ID" value="ERG89324"/>
        <property type="gene ID" value="J07HX5_01482"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005281_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="PTHR13326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="172"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="434" mass="47808" checksum="6FAFE39F8B0BCCC3" modified="2013-11-13" version="1">MRPAHPRERAVGIEHYVSDVDGVGGRLRTSPADFCVRELETLDPAPIDADPDAYPHLVVRARLRDWETTAFAGRLSDKLGISRERVSWAGTKDKRAITTQLFSVQGVTPPLPAVAEATIEPVGRTGRPVLFGDLAGNAFEIVVRDSEQPTAVSQTTATLRAFAGDDETTTVAVPNYFGQQRFGSRRVVTHEVGLAVVRGDWEGAVMAYLGGPSEREPDLTREARSFVDRTHDWSAALERFPDWLGRERAMLHALADGASFRAALESVPSSLQRLFVNAAQSALFNRMISERLDRGLPFDRPVVGDVVCFTTHEGDIVRPAPERTQRVTADRLETVRRHCERGRAFVTAPLVGTETELGGDEPGEIERAVLTDAGIEPSNFDRPGEFHSTGTRRAILLTTDLTVDRDPLQFNFRLPSGAYATTLLREYLKDPDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ41</accession>
    <name>U1MJ41_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01623</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89464">
        <property type="protein sequence ID" value="ERG89464"/>
        <property type="gene ID" value="J07HX5_01623"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="12482" checksum="D97C0BB99B9EA809" modified="2013-11-13" version="1">MLEVRNEKYIDFARAKGVSDRALVWKHIFRNALIPLIPVITSEAFLLIGGSVLVETVFGINGIGYLFFQAAIQGDLPLVGTLMYIFILITVGINLVQDMLYTIIDPRVGLEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJD8</accession>
    <name>U1MJD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01755</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89589">
        <property type="protein sequence ID" value="ERG89589"/>
        <property type="gene ID" value="J07HX5_01755"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="15117" checksum="7C5F390C4AAEC7AC" modified="2013-11-13" version="1">MSDDQTLFEQIVAGEIPSHTVYEDETTYAFLDVNPLAPGHTLVIPKQPYERLNNLPPATAADLFTVIAELAPAVEAAVDAPGSLVAAHNGAAAGQEVPHLHWHIVPRFEDDNGAAVHALFDGTDLSDERLAAIAEAVREHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJF1</accession>
    <name>U1MJF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin-like proteins and domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01772</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89604">
        <property type="protein sequence ID" value="ERG89604"/>
        <property type="gene ID" value="J07HX5_01772"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151086_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12273" checksum="3F1F6580600DEF50" modified="2013-11-13" version="1">MSTEADTRDNDLRERIRNFLRRNFPQIQMHGGSASIEEIDRDSGEVTIQLSGACSGCGISPMTVQAIKARMTKEIAEVTKVNASTGLTSGGHSRGGDIPGSDPDPGPDSDGPQAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJP6</accession>
    <name>U1MJP6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01891</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89719">
        <property type="protein sequence ID" value="ERG89719"/>
        <property type="gene ID" value="J07HX5_01891"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1072013_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046416">
        <property type="term" value="P:D-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="PTHR11530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="3">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="259" mass="28703" checksum="98FB481D50B199DB" modified="2013-11-13" version="1">MNVVSVSDYEGDLPQRPDHEVTSGYVCDEYFVEMPAYVPLLYETYCSLGGSVTRQEVSKDDVEDFLGSTAVFNCSGYGSKALFDDDSMRAIKGHIVETACDRDTPLDFAYTYTASDYGHYTYMYPREDSVIFGGTYLNGDISNGDWVGEEPIKPIHRDGKRIPERVFEVNKSIMSSFADITVDDVSVKYGFRPYREAGMRIEQDNTGVIHNYGHGGAGVSLSWWSAVKAARNIDTVPESVLSDIPTELAQVNSAKPVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJR8</accession>
    <name>U1MJR8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IclR helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01916</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89744">
        <property type="protein sequence ID" value="ERG89744"/>
        <property type="gene ID" value="J07HX5_01916"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2643517_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="76" mass="8557" checksum="504BF0AA912510F0" modified="2013-11-13" version="1" fragment="single">DPSDPGELMTDEDRVVTILKTEGGRLRQTAIAERLGWSDSKTSRVLSDMVETGTVEKLRIGRENVIDLNLRDQDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJS3</accession>
    <name>U1MJS3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01921</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89749">
        <property type="protein sequence ID" value="ERG89749"/>
        <property type="gene ID" value="J07HX5_01921"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048072_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="326" mass="34034" checksum="9E5FC6A81D9B761B" modified="2013-11-13" version="1">MGGFFAIFVVIVGPNEFISNASQLSPARFSVMLAVNGAVTVATGIALYLIARNVGLGFSPVESVFLNTTAELAHNLTPFGQAGGIPVSGAILSRRTDRPYEECLAALSAKDIVGFVPAIVIFVFGGGYLTAFDRSIPAAFRRYIAAFAVVVTLGVTVGVLVYRYQAAAFRRISRIIAWINRIVARLPRGSSLDEQEVQARIENFSDSVESVASDPPTVVAASAMTTAAVTAQGILLWLTLTGVGVSITPVVTVFIIPISLLASALPLPGGSGGVEALQTILTVAATGAPGATVLTAVVVSRGLVYWTPIVLGSMTFITMEIREQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK24</accession>
    <name>U1MK24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02036</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89864">
        <property type="protein sequence ID" value="ERG89864"/>
        <property type="gene ID" value="J07HX5_02036"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2216957_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="106" mass="11604" checksum="FF406CC1796F3F1F" modified="2013-11-13" version="1">MSPVLNVSVAAAHEGDENPVEMLSGAEKYQLANEMTRTDEFHALLQKARELGYNYRPGLEYIDAGQVEAQDWQREVVAIELVGSDDGVRTGIILGRNLGEDGLTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK27</accession>
    <name>U1MK27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02041</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89869">
        <property type="protein sequence ID" value="ERG89869"/>
        <property type="gene ID" value="J07HX5_02041"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130786_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043835">
        <property type="entry name" value="DUF5811"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19128">
        <property type="entry name" value="DUF5811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="11759" checksum="8A6A83B7E64D7556" modified="2013-11-13" version="1">MYGNTSFGAETPEELTEDEREMVQQELSAVVARTRRLLPGEFVVGSELAAGADGPTATVAVQPPVGRAVRANYTPSDAGFDEGSREELAAGLAASAAVQVREALRNDAAPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV05</accession>
    <name>U1MV05_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00036</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87895">
        <property type="protein sequence ID" value="ERG87895"/>
        <property type="gene ID" value="J07HX5_00036"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123380_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="13300" checksum="07118837F5A35943" modified="2013-11-13" version="1">MAAQEGSDYDDDLGPVIEEADDLSQPLGEVWTDGLPAYQGMEHDHRYVVHDEGYVSEDGIHTNQAECLWSLLQPWLAKFRGLSKPGLEQAARTYGFLRSLNLTGAPIHGLVDCIAVNVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV36</accession>
    <name>U1MV36_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00081</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87940">
        <property type="protein sequence ID" value="ERG87940"/>
        <property type="gene ID" value="J07HX5_00081"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490318_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9175" checksum="6565180B3D1E4782" modified="2013-11-13" version="1">MAPARIATVTRPYVLAFHRLLRPLLRGRWATALYGLRISRQGEPKAGAGEDANRSATGGPPGFEGAALGRFTPLVRSLGITFNPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV80</accession>
    <name>U1MV80_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00141</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88000">
        <property type="protein sequence ID" value="ERG88000"/>
        <property type="gene ID" value="J07HX5_00141"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="4"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="42264" checksum="A1996B85747F8737" modified="2013-11-13" version="1">MRLLITGGAGFIGGHLAETFVRAGHDVTVLDTLEPFYDLGIKEHTIETARAAASDSDGNGNGSYQFVEGSVTDEDRVDALMTDTDVVYHQAAQAGVRASVAEPRRVHEINVTGTVNVLEAARDHDIDRVINASSSSVYGKPVSLPYDETHPTEPVSPYGVSKLAAEQYVRVYNEVYGLPTVSLRYFTVYGPRMRPNMAFTNFVSRCLHGEPPVIYGDGEQTRDFTYVKDIVAANRQLLTSDAADGEILNIGSGGRITINELARVIRDAIDPALEIVHDDPREGDAEHTHADITKARERLGXXXXXXXFAVLSIAVISVSSIVVVCHAPRFACSIIVNTLSRSDGPSPRGDANGDKQVIADRDGLGGISHTLDLGACAVDILPRLKTRAFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVF3</accession>
    <name>U1MVF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00084</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87943">
        <property type="protein sequence ID" value="ERG87943"/>
        <property type="gene ID" value="J07HX5_00084"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1398904_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="195" mass="20446" checksum="2342F9E5585EEAD2" modified="2013-11-13" version="1" fragment="single">MTSYTRRGALAAIATGSLFLLVDTDAFESSEADREADVGIGDDGTALLGLTGVGSGIKTDPHNIRLTNRIEDTVDVTLSSQNNKFSFDLGGKSGNTITVRDLSSGDSTTVSVSPEETGTVSETINFEAVSQTGPESIELARTVTIERGRELATQCLFTDNKGKDLRTIGSTTDQSAAGPGQVQVEPTTLVSQQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVF8</accession>
    <name>U1MVF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type branched-chain amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00089</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87948">
        <property type="protein sequence ID" value="ERG87948"/>
        <property type="gene ID" value="J07HX5_00089"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="24984" checksum="50576DBA40BA858C" modified="2013-11-13" version="1">MTLLSIEDLAAGYDAVDILDGISLTVEDSSITAVLGANGAGKTTLLRSIVGVIEPSAGAIVFDGHDLTTQPPHEGYRRGVTLVPEDRGIFPELTVDENLRVPVTGDEMTGRSRAELYQTFPELADRRGSAANNLSGGEQQLLGIAQALRQRPQLLLLDEPSEGLAPPAVERLRTVIKEIAASGTAVFIVEQNAGVVLDLAGHVYVIADGEIVLSGPPADLRNDNRVQTYLGPSALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVM5</accession>
    <name>U1MVM5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Type II methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-4 cytosine-specific methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00308</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88165">
        <property type="protein sequence ID" value="ERG88165"/>
        <property type="gene ID" value="J07HX5_00308"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024927_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="42008" checksum="5B254FDA2784D47F" modified="2013-11-13" version="1">METTHRVVVGDARQLAAIEDNAVELVVTSPPYPMIELWDELFTELNPEIGRALQAGEGQAAFEAMHAELDTVWTELERVLVDGGIACINVGDATRTVDDQFRVYQNHARIVDAFEARGFDPLPEVLWRKPTNSAAKFMGSGMVPPNAYVTLEHEYVLVFRNGGGRRQFAPGADRRYAAAYFWEERNDWFSDLWTDITGQSQPLERPALRDRSGAYPFVIPYRLINMYSVYDDTVLDPFWGTGTTTMAALVAGRNSIGYEIESEFVDAFETRIADAPAVSQTVVEDRLRAHQQFVTAQRETGTEFDYNADHYEFPVRTKQEQSIRFHTVATVDQIPGGYRAVHEPVDRHDSTDGEDAVSNTADGSETEPGSPTPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW67</accession>
    <name>U1MW67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00371</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88228">
        <property type="protein sequence ID" value="ERG88228"/>
        <property type="gene ID" value="J07HX5_00371"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141637_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032347">
        <property type="entry name" value="DUF4864"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16156">
        <property type="entry name" value="DUF4864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="135" mass="14606" checksum="7FAC601852D80E37" modified="2013-11-13" version="1">MSTSYPIADLPTPEPDYDPARVIEIQVSALADNDDPVRNAGIKTAYNFASPANRRATGPLNRFVRMVEGPQYATMIDHTEAVAGPIEREGDQASQQVTLTGPNGQTATYEFGLSVHDGTDDVPAGCWLTDRVLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWD0</accession>
    <name>U1MWD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00431</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88288">
        <property type="protein sequence ID" value="ERG88288"/>
        <property type="gene ID" value="J07HX5_00431"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2242047_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11089" checksum="310C811385BC08BD" modified="2013-11-13" version="1" fragment="single">MDSRSRHVIEERGNRTGRVPIGAFANCYSPLNTSLSVFVDSASCLSGSSPEVSRGLVGHSHPIIGLVASGGRVGRKPGFGRIVNLKLPTAVRDSSAFTRRGTSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWH3</accession>
    <name>U1MWH3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">J07HX5_00472</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88328">
        <property type="protein sequence ID" value="ERG88328"/>
        <property type="gene ID" value="J07HX5_00472"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_2_2_2"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="10"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="45"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="224"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="255"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG88328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="30714" checksum="84684D1E2BD6E89C" modified="2013-11-13" version="1">MVTDTASPAVVVVGAYNHGVTMRVPAIPVPGETVTGDSYAEGPGGKGSNQAVAAARLGAAVSFVGRVGDDRFGEQARALWDREGVTAFVETVDKPTGVGFVIVDETGENAITVAPGANDTLDGAAVRATADTVAAADVALVQLEIGDEPVATTVDLAAANSTETVLNPAPARTLPSAVLDRVDVLTPNRTEARALAGLAPDADVADETVAASLLDRGPDAVVLTQGAAGALVHTPSQTTTVPGPSVKVVDTTGAGDAFNAGFAVARAEGTTLADAARFGTVVGSLTCTGSEVIPALPDRATVEAHTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWH9</accession>
    <name>U1MWH9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00625</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88480">
        <property type="protein sequence ID" value="ERG88480"/>
        <property type="gene ID" value="J07HX5_00625"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1507350_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043827">
        <property type="entry name" value="DUF5804"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19120">
        <property type="entry name" value="DUF5804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="210" mass="21958" checksum="62B93F2CFA5E70E2" modified="2013-11-13" version="1">MTQVCLCGASDTTLWSELLSRETSRGALTAYELSEPYTNTVALETVSLGAAVALLNDLNWHLARFVADALVLEPSVSETEWLSRELAAAIRHDEVAPVASGQYLKIYGVTTDPSSAATDGTGDAPTDTNANANANASSTDRLAPGAIGGVETADTPGSQRQLVEPMFVKRADASAAVPEYDLQPVAETVYVRVSKSEFVSGPGSGGDHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWJ0</accession>
    <name>U1MWJ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00640</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88495">
        <property type="protein sequence ID" value="ERG88495"/>
        <property type="gene ID" value="J07HX5_00640"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020818_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6149" checksum="35CF80AECFB6D6F0" modified="2013-11-13" version="1">MLRVCLTNPREEASGLDPEAVHADYSISGVEVGYVEANTVREWLQAFTLAWDQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWP7</accession>
    <name>U1MWP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00538</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88393">
        <property type="protein sequence ID" value="ERG88393"/>
        <property type="gene ID" value="J07HX5_00538"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1869313_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="138" mass="14168" checksum="1CC6D012111651A1" modified="2013-11-13" version="1" fragment="single">MANSLIQRLKQFLGRGDDDESAQTSNGTDGASVTVERTPGEQSSVASTHDSGEPTGEAGTSPDDEQESEIVSTPDTDTGADTGPGPDADVETSTDIVDDAVSKETHEADDDHSGAETDTAAGVDTITGIGPTYAQRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWX9</accession>
    <name>U1MWX9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menD</name>
        <name evidence="8" type="ORF">J07HX5_00801</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88655">
        <property type="protein sequence ID" value="ERG88655"/>
        <property type="gene ID" value="J07HX5_00801"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006051_3_0_2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="11"/>
            <end position="182"/>
        </location>
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        <location>
            <begin position="231"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="428"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="566" mass="60218" checksum="7ABB8794D2CECC6D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWY7</accession>
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        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88493.1"/>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013603">
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    </dbReference>
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        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HTHASNC"/>
    </dbReference>
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        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="199" mass="21446" checksum="EB973EA0ABC755B5" modified="2013-11-13" version="1">MNSLDETDLKILQLMISNARRPYSDIAEVVGLSAPAVSDRVARLQEMGVINRFTLDIDRSQLQGGIPVLITLKIASTGSAIASIKQDLLNDGAVEHVFTTAEANLVIYAKVPDNDIADWLAGSLDNGVFDSFEVTLLTGADWSPDLGGTEFGLTCSQCGNTVDSEGTATRIDGELYQFCCPSCETQFTEKYDQLQQGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWZ2</accession>
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        <submittedName>
            <fullName evidence="5">Transposase</fullName>
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    </protein>
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    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88498">
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        <property type="gene ID" value="J07HX5_00643"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="3"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="9236" checksum="B1C76E6D9E8246F9" modified="2013-11-13" version="1">MLDAYYNSKMCSCCGERGYQQGQRFQCMNGECDVAQDHAEPNASVNIAWREKAELDGKITNYRTHKTNHRFGWCVCPGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWZ5</accession>
    <name>U1MWZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00816</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88670">
        <property type="protein sequence ID" value="ERG88670"/>
        <property type="gene ID" value="J07HX5_00816"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="173" mass="19433" checksum="6F7AA632B6CF256F" modified="2013-11-13" version="1">MWRCLSVSDEPQPRLVAVGGLPGAGKSTVAGQIATRLQARRLRTDELRKELFDSPRYTDTETTAVYRQLCDRATDRLRADESVVLDATFAQRQHRRAVHEASRDHGAVFRFVLVVCDQSVLESRIVERDGISDADLSVSRQFRSSYDPVEIAHETIDNSGERAETRSQVAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX58</accession>
    <name>U1MX58_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00714</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88568">
        <property type="protein sequence ID" value="ERG88568"/>
        <property type="gene ID" value="J07HX5_00714"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1830533_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010115">
        <property type="entry name" value="FbiA/CofD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43007">
        <property type="entry name" value="PTHR43007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="140" mass="15043" checksum="64D17C351455F26A" modified="2013-11-13" version="1">MVTFLSGGTGTPKLLSGAASAFPPTETTVVANTGDDILLGGGLVCPDLDTLLYLGGDELDRNRWWGIEGDSTDTHEELQALATAAGVETGPRYLPAERQTEGRRIARWRRFTAVGEFMLIGDHDRAVHSLGPAVSMRDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXB0</accession>
    <name>U1MXB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00926</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88780">
        <property type="protein sequence ID" value="ERG88780"/>
        <property type="gene ID" value="J07HX5_00926"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968315_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="5969" checksum="B6BCC5B818BB720A" modified="2013-11-13" version="1">MTVSTRMTCLSHPDADGLLANYYSRQPLLQPTVLTAPAETGGGAAPILVTPGGTDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXG6</accession>
    <name>U1MXG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase small domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00986</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88840">
        <property type="protein sequence ID" value="ERG88840"/>
        <property type="gene ID" value="J07HX5_00986"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2710346_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="73" mass="7587" checksum="4E4C0FEE64EA9D49" modified="2013-11-13" version="1" fragment="single">MPTKSGLTQRLGVVAGFSNPRAALEQYRTPPRLAAEIVHLADLQDDIAGRTVLDLGCGTGMLALGAALRGPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXI2</accession>
    <name>U1MXI2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00859</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88713">
        <property type="protein sequence ID" value="ERG88713"/>
        <property type="gene ID" value="J07HX5_00859"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3054601_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="54" mass="5904" checksum="99FCFCCC46902270" modified="2013-11-13" version="1" fragment="single">MYPAPTTARLSGTDCNPSAVCEEMICYAVKLEAGYLDWPAPGCDNSMFELNRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXK4</accession>
    <name>U1MXK4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH-quinone oxidoreductase, B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00884</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88738">
        <property type="protein sequence ID" value="ERG88738"/>
        <property type="gene ID" value="J07HX5_00884"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="3">
        <location>
            <begin position="70"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="234" mass="25928" checksum="395830E1C36CA0D1" modified="2013-11-13" version="1">MSGDGRPQGPPSGAPAQTDSQSQSQDRDRFGSRLRAALGTTPFVLTKLDQFMNWARGNSMFMLQFGIACCSIEMMHSYATKHDLDRFGAGVPRASPRQADVLIVPGTIVSKFGPRMQRIYDQMPEPKFVVSMGSCTISGGPFHDGYNVIGGVEKIIPVDIHVPGCPPRPEALIYGVLKLQERIRSGEAEHVPVTVKPYEIEAFGDLERDALVEQLTDEIDADDLVMRYDWETRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXL9</accession>
    <name>U1MXL9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00899</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88753">
        <property type="protein sequence ID" value="ERG88753"/>
        <property type="gene ID" value="J07HX5_00899"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754618_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="17136" checksum="75EA5516D5F15FBD" modified="2013-11-13" version="1">MEIQRTAVVKLSVPDERRDDLKRTMNTFRDAAQRFADRGWDGDDDGYVITSRSRLQPLVYDEIREDTGLHSDLTVAAVNHAADALTGCVDRMKEGERTSKPVFTSNTTVYNTNAISYFDGYCSLAAYGSGRVHAEYVYPDDSPQTEYMESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXP3</accession>
    <name>U1MXP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01051</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88905">
        <property type="protein sequence ID" value="ERG88905"/>
        <property type="gene ID" value="J07HX5_01051"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_788955_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="93"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="352" mass="36870" checksum="293A9798C2759C26" modified="2013-11-13" version="1" fragment="single">MTLSSDLITLLDQVSPALVLVVLALSAVMLARLTRWSPVGRLRQRLVLGVPWGTLVIIGGLAGVYYGVQGGGEPGGPVATGFRSWSLWYPEGLVLSSFAHASNGHLLSNATATLAFAPLVEYVWGHYSATDRTDWLGQPVVRISGFVLGVGSVGLAGSLFVPGAVIGFSGVVFAFAGVAVVTLPLALVFAMLGLQVLRLVQSAFEAPLVLARAQETFVSPSWADTAVQGHLFGLLIGVIVGIVLVRRRNLSPDLRYVWFAALAFGVTRGLYAVFWYQGTDSFLLFRGLGTAGVFVLAGLIAGAVISTDRPIVPRAGITSRELSVGVVLAVLFALALVAVPYNLVTVGPGEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXW9</accession>
    <name>U1MXW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01145</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88995">
        <property type="protein sequence ID" value="ERG88995"/>
        <property type="gene ID" value="J07HX5_01145"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077869_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017271">
        <property type="entry name" value="Tscrpt_reg_HTH_MJ1545_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037724">
        <property type="entry name" value="TF_HTH_MJ1545_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="25881" checksum="2CE28578274ED19F" modified="2013-11-13" version="1">MTRGPRAELAEKIAGEVVLSDDPGATLRKWRTDFEVPQTALADELDVSPSVVSDYESGRRGNPGVDVVRRIITALLDVDERQGADHIRQYARVLLAGFDSDVVYDLQEYAANIPVERLHEATNATGLVAGDRDTVAGHTVLDSVEVIRRFSREEFYSLYGESTNRALVFTNVTDGEGPMVALRVVQFTPHAVVLHGIDENDLWERAAELARIEGFTLALTEMPLDGVLDGLHELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXY3</accession>
    <name>U1MXY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GvpH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01170</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89020">
        <property type="protein sequence ID" value="ERG89020"/>
        <property type="gene ID" value="J07HX5_01170"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1451371_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008633">
        <property type="entry name" value="GvpH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05455">
        <property type="entry name" value="GvpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="186" mass="20129" checksum="6467E76FE1B093EC" modified="2013-11-13" version="1">MSDREAAETTWSGVVRTQLSSIGDALTEIETGATGPRQRSTQHNTGLTQVEYGYSVSVGLAAMTGQPDAADTAQSGRDPLSAADRPDTDSQFQRSRSRPQSPKVTVRTQGAETRELIVDRSDIPEKDLQIVYNPDTAIIDLWAEGRRVERVPISQAAFAVTDVQTSDEVLTVVLTRQHDTGGTNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXY8</accession>
    <name>U1MXY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gas vesicle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01175</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89025">
        <property type="protein sequence ID" value="ERG89025"/>
        <property type="gene ID" value="J07HX5_01175"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161794_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000638">
        <property type="entry name" value="Gas-vesicle_GvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00741">
        <property type="entry name" value="Gas_vesicle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9561" checksum="F6C9F94D6114AF36" modified="2013-11-13" version="1">MEPTKSKGQVVDLVDVLLENGAVLAADVVITVADVPLIGLQLRLAVAGMARMTELGLLADWDETLRKQHTPSPVVTTAICQTDRGGACRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY64</accession>
    <name>U1MY64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01106</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88958">
        <property type="protein sequence ID" value="ERG88958"/>
        <property type="gene ID" value="J07HX5_01106"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_788977_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="361" mass="39797" checksum="AD16423FEE28EAFD" modified="2013-11-13" version="1">MSLYHAVADLSFTLETVAHHQHRADTTSGFERATTEFVLSGAGETGRGEDVTYAVSAHDRLAKANNDNDNDNDRDTDNDHDLDFPAGEYSFDEFSGLLADTTLFPAGQPPDPLARNHRRWGLESAALDLALCQAGQSLPERLERTTEPVRFVVSTRLGEPPTIDRVERLLEADPTLEFKLDPTMAWPEVLFERLRATDAVRVLDLKGWYEDTEAAVEADPELYRDVFAAFPTEVVEDPAITPETQPLVAPQADRLSFDYPVASVDDLRSLPVDPGWCNIKPSRFGSVQSLFETIEHCQDQNISCYAGGQFELGVGRSQIQTLAALFYPDGPNDVAPRAFNNPEHSGTYPTSPLAAPTGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY79</accession>
    <name>U1MY79_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01123</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88973">
        <property type="protein sequence ID" value="ERG88973"/>
        <property type="gene ID" value="J07HX5_01123"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050517_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="323" mass="34898" checksum="5153C89405F05A0E" modified="2013-11-13" version="1">MTVQYRDGIEIELSDGTRVVCDADDPDGDIAVVSHAHGDHLPYTETEQTAVCAPLTAAVGTARMDGTIRATTHPQVELRPAGHVAGSRAAIIDDPDGTRYCYTGDVSTRSRHYLEGFEPPNVDVLIVEATYGEPPYEFPPHEEVTDEIVAWLDDTDAPVVMLGYAFGRAQKLQLLADRAGRARVLTTEGVLRINKPIERELDVTFPAEPFDAAELRPGDALVLPMTSGRIDWVDRLASEAGAVTAGFSGWAVDSSFKFRGDFDVTFPLSDHCDFSELVALVEAVAPETVYTQHGAAATLATELTARGHDATALRQGQASLDQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYA3</accession>
    <name>U1MYA3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01148</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG88998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="16858" checksum="C60CD13208595224" modified="2013-11-13" version="1">MDLDRFAADSPDDDAPGEAAVCVVATQSETFDRCRDGFYPSPRSYQRTRKSFEYMAFYRTAPVSSITHYARLTERVPQTRGGAGPMDEADWAALIDPFSDEDQVIVFTFDELVPLETPVTNNMNGVRGAWYCTVADLRAAPTLSALADRAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYB9</accession>
    <name>U1MYB9_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01163</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89013">
        <property type="protein sequence ID" value="ERG89013"/>
        <property type="gene ID" value="J07HX5_01163"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23923" checksum="EA2F9A01178DD876" modified="2013-11-13" version="1">MLPSRVDTLVDVGYGSLLAIAVVLLVVVGQLAGIAFALGVFAAYLLHVVWKMARYDPEWMTRAVEETVEKTVGKQVDETVTETVEETVEESVDKAVGKQIDDSVDSVVETAVERQVDADVTTAVRETVAQQVDADVGSAVETAVEEQVEDTIGETVETAVEETLEEQVEEQVEPEVEETVEETIERTVDDSVLEEATETDPSDDTDDTDASSQSKERQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYJ1</accession>
    <name>U1MYJ1_9EURY</name>
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        <recommendedName>
            <fullName evidence="5">Tubulin-like protein CetZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cetZ</name>
        <name evidence="8" type="ORF">J07HX5_01395</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cell shape control.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <text evidence="1 5">Belongs to the CetZ family.</text>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
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    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="2"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
    </feature>
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        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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            <position position="214"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="444" mass="47706" checksum="69646E77E65D5610" modified="2013-11-13" version="1">MQVGAIGIGQAGGKILDTFLAYNQEIAESPIRSALAVNTAETDLLGLTHIGDDQKLLIGEDTQNGGGVGADNKTGAQVTSQSIERIHEGLEQMPRHELDGFLILTSLGGGTGSGGTPVVTRHINSMYDSLPVYVVGVLPSKREGQLYAYNAARSLQTLLQTGATVDDDDQPTSGPDGATQTGAETAIIGPDESINDAREAQTEPLADGIILVDNDAYSRPDESLEQAWEYINRTIAQAVTDLLAAGEPANKADVPENVVDTADIEQTLTNGRLATIGYATTDLETDTTQTLLDRLRRTSSTDIENHNFDQQEAELRIMNLVREATQTTLGFDTTLESTEAGLVLVAGPAEALNHRGIQRSRDWLQDQIQTPAVRGGDYPRDQPEVQTALLLSGVHDSDRLRELYAQAAKARQTIEDTSDAELPSTALTDSPTPPNYEHYINSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYQ0</accession>
    <name>U1MYQ0_9EURY</name>
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        <submittedName>
            <fullName evidence="3">TraB determinant protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01311</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89158">
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        <property type="gene ID" value="J07HX5_01311"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032780_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="486"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89158.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="515" mass="54837" checksum="4D49917E54DA968D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYS8</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01342</name>
    </gene>
    <organism evidence="1">
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        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89188">
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        <property type="gene ID" value="J07HX5_01342"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="202" mass="21992" checksum="7B632887F8A5D07B" modified="2013-11-13" version="1">MYETRTRRQLVEHFAEGEGSWQTAGNIASARDLSRPVIADGVEFLVLAGLVNSKNERRFTQYQLARDSAPYAAVKAANRALAGAASPPPEHNGTPLALLYGSKTRRELVDLFLEAGVGWTDDDDPLSTRGLTTHCGGDWSTIGDEMELLHAHAIAAENDGFGYSRYLPRVESQPFQRLLRLNEALAAAVKGRAGKRDSPATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZC6</accession>
    <name>U1MZC6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01726</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89560">
        <property type="protein sequence ID" value="ERG89560"/>
        <property type="gene ID" value="J07HX5_01726"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="25108" checksum="D9DE90C493F77C28" modified="2013-11-13" version="1">MTDEPTVELYNSLAEQVAVVTGATRGIGAAIAAELTDLGATVYAGARDTDDITAADQRALQLDVTEDREIAAALDRVEREAGRLDVVVNNAGIFPRESSLHELETAAYDRTMAVNLRGPTLVTKHALPLLLDRAGGRVVNVSSNLGRQATLGSSYPPYRISKIGLGGLTQYLHAEYADDGLIANAVSPGWVRTDMGGPEATRSPSEGADTPVWLARFRPDSSGGLFWKDRSVQSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZC9</accession>
    <name>U1MZC9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01731</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89565">
        <property type="protein sequence ID" value="ERG89565"/>
        <property type="gene ID" value="J07HX5_01731"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1615251_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="2">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="164" mass="17537" checksum="74867C6A30960C99" modified="2013-11-13" version="1">MDLFGSSGVRGVAPGDLTPELVLRVARAAGDLFGRGQITLGRDTRKTGPLLASAAASGLAAAGCSVDRLGVVPTPALQAYCDRESAPGMMITASXXXXXXXRRHWCCSRRRRRPCNILRRNRNVYSGRRGTGGAGGSCARLRRHCGFGGQRLTATCRCRRSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZF0</accession>
    <name>U1MZF0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01576</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89418">
        <property type="protein sequence ID" value="ERG89418"/>
        <property type="gene ID" value="J07HX5_01576"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965470_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="14062" checksum="E2E854B425458BB0" modified="2013-11-13" version="1">MTTRTRSPEKVIIVVLTDGKKSVLEIPDEVVRDRVETRRDDNHNRESLPIGATQDGALTVEKIGMTANNSPDMAHNDTGAENVLGQRHNKSARYVRLALPTATPRRTGNANKAQTNIRLSFELLTNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZH6</accession>
    <name>U1MZH6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01779</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89610">
        <property type="protein sequence ID" value="ERG89610"/>
        <property type="gene ID" value="J07HX5_01779"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_8_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="1">
        <location>
            <begin position="18"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="34729" checksum="09586FA839CFDB93" modified="2013-11-13" version="1">MNFGYQEVCLEHEPGPRHPERPGRLRRIRRALADRHQVSYTTPASGTREELLAVHDAEYVDAVESFVANGGGSWGADTVASDATWTAALASAGLARWAASTALDGATGAATPFALGRPPGHHALADDAMGFCFFNNTAVATEHARRAGASRVAVIDWDVHHGNGTQKLFYDRDDVFYASVHEANLYPNTGEVDETGVGSGAGTTLNIPLPPTAGGPAVVTALKELIGPAVVAFDPDAVLVSAGFDGHRDDPISQLQVSTEDYARLAAAVETLAADAGAGLGFILEGGYKLDALAASVRTVQEVFAGYEPSPTDATPSAAARRVLHRVDEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZM4</accession>
    <name>U1MZM4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01663</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89498">
        <property type="protein sequence ID" value="ERG89498"/>
        <property type="gene ID" value="J07HX5_01663"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2595142_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="80" mass="8633" checksum="F28AEB8EA6E29824" modified="2013-11-13" version="1" fragment="single">NDPAANFSSVGTARSKDVRYQFMSLFNTPDLRAPLSGVVRLMQTGALSIAIDRRYGLAEAAAAQQAVLDESFFGKLVIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZP9</accession>
    <name>U1MZP9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF402 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01857</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89685">
        <property type="protein sequence ID" value="ERG89685"/>
        <property type="gene ID" value="J07HX5_01857"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1221835_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007295">
        <property type="entry name" value="DUF402"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035930">
        <property type="entry name" value="FomD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04167">
        <property type="entry name" value="DUF402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159234">
        <property type="entry name" value="SSF159234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF402" evidence="1">
        <location>
            <begin position="134"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="24305" checksum="A04F4B705A1272BE" modified="2013-11-13" version="1" fragment="single">WADTATWWVWFGRESRWALDDRRRTVTPTMPGHHRIKAGAETASAAVDFVESVCGAAAADGAFPVDAVTRQFGPTAGDKIAIGHGKPDGRQYDLGPATVTDRSPDGTVTVERELTPGGTYDGLGTTIHAGDSAVTKLTESRWWYPTVYRSSDGTRRGTYVNVCTPVELFPNQARYVDLHVDVVHHADGRVERVDDDELTAAVEADNVTPALAAKARDVADAVASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZU7</accession>
    <name>U1MZU7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01749</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89583">
        <property type="protein sequence ID" value="ERG89583"/>
        <property type="gene ID" value="J07HX5_01749"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019748_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="340"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="495" mass="51618" checksum="E885D4CBE5C32B2D" modified="2013-11-13" version="1">MSGSVPDNDPPARVAGDVSVVTAETAAAAIPDGATVAVSGFGSVGDPKAVPRALARAADAGDRDPELTIVSGGSVGEPLDTMLIEAGGVDRRYPFVATDAARAAANNQSVAFADCGIAGLSDEVRFGRVADPDVALVEAVAVGPDWLIPSTSVGQTPAYVRAADELLVEVNAAQPRELARFHDIVVRDSPPERGAIALDSPGQRIGDPTVSFAPETLTGVIRTDERDDPYQFRAPTDTDRAIAANLTSFLERAQETDPVIGAAPTLQFGVGSLGNALMRALADSSLADGETGLRYFGEVIQDGLLDLVESGGLEAASATSLALSAEGQDRLFGDPTRYVDDVVLRPSELSNAPALIDRFGVVAVNSAIELDLYGHINSTHIRGSRLVSGVGGSVDFNRNAHLTVVATPATAAGGDISTVVPMVTHVDHTEHDVDAVVTEHGTADLRGLTPVERAERLIDVAAPTFREDLRAYLERARTNGGHLPQDLATAFDWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N065</accession>
    <name>U1N065_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01880</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89708">
        <property type="protein sequence ID" value="ERG89708"/>
        <property type="gene ID" value="J07HX5_01880"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1615259_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18784" checksum="831B42D020E8FB2E" modified="2013-11-13" version="1">MHSSFVRAKPLQALKLTAVVGTVVLAGVGMARMLPGGQVTGLLLLLFTPVLITVAVTVETLLTGIRLVQADNLAARLTAHYKYTLIRTIELIVTVFGLGRFYLFVYQNGDEFRGDVPALGLAFIGVFLDIAACAVVLLRTLTEYYIHRKQSDRSKANTRGGERHRIARHMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0A3</accession>
    <name>U1N0A3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonucleoside-diphosphate reductase, alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02032</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89860">
        <property type="protein sequence ID" value="ERG89860"/>
        <property type="gene ID" value="J07HX5_02032"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_7_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013350">
        <property type="entry name" value="RNR_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02510">
        <property type="entry name" value="NrdE-prime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="2">
        <location>
            <begin position="91"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="2">
        <location>
            <begin position="215"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="2">
        <location>
            <begin position="389"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="562" mass="63988" checksum="6042DD6DA26BB017" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0G4</accession>
    <name>U1N0G4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative GTPases (G3E family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02108</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89935">
        <property type="protein sequence ID" value="ERG89935"/>
        <property type="gene ID" value="J07HX5_02108"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="124"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="263" mass="28775" checksum="1C55904BA6C14ED8" modified="2013-11-13" version="1">MTQAEHANVVLVNKCDRASEEAIAETEALLEALNPDARRYRTRHGAVEPGTILDTGLFSPESLSVGDRRERVLEQADAETTPEAEASGAGAGTEVGGGVGDHDHDHSHDEHDGHVHDPAETYGVTSIAFESRQPLHPERFAAFLRGLPDSVIRSKGLVWVAGRDELALRYTGTGSARRVIGREPWVAAMSKQRQETQRRLQPDLPWDEAVGDRRTELVFIGRQMDETALEAELAACELTDDEQGALGRAENPFPSEEGKELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0I6</accession>
    <name>U1N0I6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-methylhydantoinase A/acetone carboxylase, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02005</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89833">
        <property type="protein sequence ID" value="ERG89833"/>
        <property type="gene ID" value="J07HX5_02005"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002157_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
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        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
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        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="1">
        <location>
            <begin position="4"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="211" mass="22738" checksum="AC8614D9CABD1955" modified="2013-11-13" version="1" fragment="single">MTLRIGVDTGGTFTDVVAYDTETDTVHVKKTPSTPPQFETGVITGIEAAIEASDAAPATVSFLSHGTTVGTNAVLEEELPELGLITNAGLRDVLAIGDQTRPELYNLQTEKPPSLIPRQHRLGVPGRIDATGSVVDELDEPAVRSAVRELAEDDVDAIVVAMVFSYLNDSHEQRVGELIEAEADCQYALSSAVYPERREYDRTVTTVLNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0Y7</accession>
    <name>U1N0Y7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02156</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89983">
        <property type="protein sequence ID" value="ERG89983"/>
        <property type="gene ID" value="J07HX5_02156"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3263660_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4115" checksum="AD41C1521871D058" modified="2013-11-13" version="1">MSVTDGTNVQAVLEAAVAAVAYDPGLPVDSRDSVGGNSQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P360</accession>
    <name>U1P360_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00058</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87917">
        <property type="protein sequence ID" value="ERG87917"/>
        <property type="gene ID" value="J07HX5_00058"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082632_10_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="111" mass="12163" checksum="53105C88980F38A2" modified="2013-11-13" version="1">MRNELKRSELVGTSMPTISYDGETYECEEGERLRDVLLENGASPHTGITNQLNCNGHATCGTCAVRITDGQTGEATGIERTRLSVARHDDSASVRLACQYEVETDMTIEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P374</accession>
    <name>U1P374_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein conserved in bacteria (DUF2309)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00078</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87937">
        <property type="protein sequence ID" value="ERG87937"/>
        <property type="gene ID" value="J07HX5_00078"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558418_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018752">
        <property type="entry name" value="DabA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38344">
        <property type="entry name" value="PTHR38344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10070">
        <property type="entry name" value="MpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="488" mass="52102" checksum="0BCA3E807EFE0F08" modified="2013-11-13" version="1" fragment="single">AAGSYETHGYAGFFGVPMRYDSYDSPVTVDACPPILDPRHRIADRPTDNTGDAGERRTNYDRLTAARAAGARAVKRLTSNAATAYSFVESTGAGYGAALTTRTLVPGRVYDLFAAIERRVPNTNEFCTPAIGHDPETGSELPAGLSLEQRVEYAATAVELMGWQQFARLVVFVGHASQTTNNPFDASLDCGACAGNPGGPSARVLAAICNDEAVRAKLRERGIEIPADTVFLAGEHNTTTDAVTLYDTGLPETHAAEVDELRAALASARAGAAAERAGDMGAEPAAGVRETERRAADWAEPRPEWGLAGNASFVIGPRGLTTDLDLDGRAFLHSYDWRTDPDGDALAAIMQGPMIVTQWINTHYYFAMVDPAVHGSGSKVTQNPVGNVGVYQGNGGDLMTGLPRQSLMRADGAPQHQPLRLSTVVHAPLERVRATLAGCQTVQTLLDNDWLSLTVVDPKTHRAHQYTGNKTWRSAAETGPSRQTDTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3X6</accession>
    <name>U1P3X6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00360</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88217">
        <property type="protein sequence ID" value="ERG88217"/>
        <property type="gene ID" value="J07HX5_00360"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2627439_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8459" checksum="1DC3E9B04A67B05E" modified="2013-11-13" version="1" fragment="single">APERNIPWSRYYLILGGFHLAVSVAVLAVAPSSGAIPIGAWGVFVAVSILASALAHRYYKKQMCIGEGDRPPELRHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P488</accession>
    <name>U1P488_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00461</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88317">
        <property type="protein sequence ID" value="ERG88317"/>
        <property type="gene ID" value="J07HX5_00461"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="31113" checksum="E570274131DFB74F" modified="2013-11-13" version="1">MLGLPPDSLFQAVSWVRWGSSLGGGVGLAIGIFEARGIERAVEVERERVRAEAAASQEEFLEYLNTMLRHEVLNTATVVGLHADLITQECATDAVADRAETIITHTSEMEQVIKDGRLLVQASKDQADSETVDITAVLADEIAKLERAEVPVSVTASLPERALVDAGTPIQYVFQNLFWNAVEHADDTIPDIKVSLQRDAVVSITVTDTGSRIPADEQAALFDPEPRDDSSHGLDLVLAQTLVEGYGGTLELTETSLAGTMFRVTLPRATAPEVTDTAATPARAGRPGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4H6</accession>
    <name>U1P4H6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00542</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88397">
        <property type="protein sequence ID" value="ERG88397"/>
        <property type="gene ID" value="J07HX5_00542"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="448" mass="48905" checksum="B5CD5FCA8F4987C9" modified="2013-11-13" version="1">MSESDDPEPGFGNQRVRQIYRNGMYNDETPEYPIKYQALRERAWEQMDESARAYVQGGSGTEATFQNNQQFSQHQIMPRMLRGVEDRELTVDLLGNRHPFPVMITPLAAQSLLHEEAELATARACAELNVPFTLSSLSSTPMEEVANALGDTTKWFQLYWSSDQAVVKSFLDRAEASGYDAIVLTVDAPTLGWRDRLIAQGYYPFVDGHGTGNYFSDPAFREPLDVPPEENTAPAVERFLEIFGDESLTWEDLSMLRANTDLPIIIKGVLHPDDARLALEHGADAVQVSTHGGRQVDGAVGAIEALPDIAAAVGTDAPVLFDSGVRRGSHAFKALALGADTIMLGRPFAYGLAMAGQDGVRWVLENLLAELDLTMGLAGYDDVTQIDTAALRGDSXXXXXXXWSTSSPALLRSVISVSNRSFGAKYISSVISSRVSAFGATWSSHSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4Z8</accession>
    <name>U1P4Z8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00753</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88607">
        <property type="protein sequence ID" value="ERG88607"/>
        <property type="gene ID" value="J07HX5_00753"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_11_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20238" checksum="77E8AEAA0B723798" modified="2013-11-13" version="1">MTAPTPEFRRYQPADADAVWQLHEWALRDAGTDPTDLPGVDDLRTIEQTYFDRDPPGAFIVGIVPPTTTTDADILQTTDGCVVAMGGLLPSNAGYDDERTVADAAELHRMRVAPSYQRNGYGRRLLIALEHRAQGRFDRLLATTADRQTAAVELYTSAEYERVGTSTYDEYQLVHFEKDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P508</accession>
    <name>U1P508_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00768</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88622">
        <property type="protein sequence ID" value="ERG88622"/>
        <property type="gene ID" value="J07HX5_00768"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2693287_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="75" mass="7938" checksum="8D4D1E8D0D15BAAC" modified="2013-11-13" version="1" fragment="single">MVDLIGQAANVARNLRYRQGAAVRELAARVVYSVRSTTTAAPVLGADWDVLVVLDACRADLFEAAVADGAHDTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P572</accession>
    <name>U1P572_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00843</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88697">
        <property type="protein sequence ID" value="ERG88697"/>
        <property type="gene ID" value="J07HX5_00843"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3282728_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4238" checksum="B1847E40D1F3D885" modified="2013-11-13" version="1">MPAHSDGLPNTTLFSGLGGLAWTALWLCEPAELPCVLLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5G3</accession>
    <name>U1P5G3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain acyl-CoA synthetase (AMP-forming)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00923</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88777">
        <property type="protein sequence ID" value="ERG88777"/>
        <property type="gene ID" value="J07HX5_00923"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1536605_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="56"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="174" mass="19486" checksum="BDE294989656E2B8" modified="2013-11-13" version="1">MSKPTEPTPDEPRPSDSTTTETNSATETGPAIDQVVSAPEGDIEIIDQALPQVLLEHVEENGDDIALRWKQYGVWEEFTWTEYYERVKWFALGLERLGFGAEDVLFSIGYNRPHQLWSWMGAQTLGGMAAPNYEDMLPEAIGNQLELLNPRVAYAEGQEMVDKLLQVSDRAPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P623</accession>
    <name>U1P623_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01147</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88997">
        <property type="protein sequence ID" value="ERG88997"/>
        <property type="gene ID" value="J07HX5_01147"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2091220_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12893" checksum="65229CDDD6C1D782" modified="2013-11-13" version="1">MEGVTLGVRPVRTASCARDETLPFRIDRLSPSARASYRIGPVNIHSGDTFIRLATMFTVAMCHHYETTNWRRDVTDETEDEEAGQLDEGATKPSFLNEDASEEDVEIVTDGGNTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P693</accession>
    <name>U1P693_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01229</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="9633" checksum="0AA2516AAE76538E" modified="2013-11-13" version="1">MDVTLLEVELNGGEFTANAPLSFVGETEQTDEMAGDESATDVSGERNKDSTSTGSSKRRLLVGLVVFSIAAVLAYYFAGGSTTETDTDADDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6I0</accession>
    <name>U1P6I0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01330</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89177">
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        <property type="gene ID" value="J07HX5_01330"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1122589_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="25195" checksum="5470B3DA0375C2B5" modified="2013-11-13" version="1">MWSDRDRVRATEPSRRRLLAGVGGLGSTATLLGAGVGVTGGTIQPAQPTARWQYAADEVSNTIGHDGVYYFTTGETIQAIDATTGEIGWTTGAGGPIGEDAAAIDVENDILVTTSERGAALGVALANGSERWRRSAAGAGIGAVVADGTAYLLAGSTVQAVEAASGDPLWSHSIPEAVDGQSKGLAVASTDSGVVPVYHTSNYLIGLNNSGDRAVASGATGPGIRREPIRLQQQQHRLTGAVCLLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6T3</accession>
    <name>U1P6T3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01439</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89282">
        <property type="protein sequence ID" value="ERG89282"/>
        <property type="gene ID" value="J07HX5_01439"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020884_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="29"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="285" mass="31430" checksum="BB999080F37BCE18" modified="2013-11-13" version="1">MVHSTWGDWFVTEEVEAVRPSGVSVWYLGCNGFIVRSAETTLYIDPYFGDGDPPNVVRMIPVPVDPADVTLCDAVLVTHEHIDHTHPPSYGPLVEDLGAAIHAPSAAYTDPDYDGPLRAPADRRHTVAVGDRFTVGDFTVHVRGANDPDAIEPVTYVIEHDTGVIVHPGDSRPAEAFHEIGESFEIDLGVLAVGSKGQIHYPDAGETRRTEWYMSENQAIEAANALRLGRLLPSHFDIWRGMNADPKSLHEHATAHEYPHVIETPRVGDRFDLARPGTVRPMILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P773</accession>
    <name>U1P773_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketosteroid isomerase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01550</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89392">
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        <property type="gene ID" value="J07HX5_01550"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1801632_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
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    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="16011" checksum="C537D5E59BE50BB7" modified="2013-11-13" version="1">MKSPTSQNNRMSVETAERYFELADDPDAGPADIAALYAADATLLSPREGTFHGRDEVRQFFELNAEFFATGAHHIDRYHVDGDTVVCEGWIEGRTAAGRSYEGVGLTDIMQFNDADEIQQLRVYLDYSAILTEIPDEAPDFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7B6</accession>
    <name>U1P7B6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00172</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88031">
        <property type="protein sequence ID" value="ERG88031"/>
        <property type="gene ID" value="J07HX5_00172"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2565583_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="9015" checksum="1577697C41DEDDF3" modified="2013-11-13" version="1">MYDMMTWVRHNTLVRQTXXXXXXXKQPRTTHVESTGLDQGSKNAVNVGETAAACQYRATASTRSSRNGSRSMSTPTRVFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7G4</accession>
    <name>U1P7G4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00223</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12534" checksum="210B3DC6586F19E5" modified="2013-11-13" version="1" fragment="single">PLYVSSVIILSVCVGSGLRLRTQTWAQTGIEAAEQRAQLRRLFRRDKGVLGCIQFVGLGATLTAISVAPSATQALILFKSNIILVVLVSTTRLHEGHRLRRTLGAAVIAVGTVLAVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8V4</accession>
    <name>U1P8V4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02145</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89972">
        <property type="protein sequence ID" value="ERG89972"/>
        <property type="gene ID" value="J07HX5_02145"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="1">
        <location>
            <begin position="41"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="336" mass="36011" checksum="41E0C3B89F33C1F2" modified="2013-11-13" version="1">MARYEPVESPDESTIFPYHELTPPTVADVYAARKTIAGELPETPVVRADGLSAELDADVYLKREDTLPTGAFKVRGGLNLVAGLEERFQEPGLIAASTGNHGGSVAYAADRFDIPATVVVPEGTTPAKIQRMERLGATVKRRGKTFDQAREHAERLAREGYRYVHSANEPALLAGVGTAGLELVEQRPEIDYLFCPVGGGSSAAGYALTVGRLTDATVVGVQSEAAPAAHRAWAEDTLEAHDRVETFAEGIATRVPFALPTEILQADLDAFRLVADDTLRAGVRTMFEHERIVMEGACAASLAGARDMAEEIAGTTVVLQVSGRNIDPALFRELID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8W1</accession>
    <name>U1P8W1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00722</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88576">
        <property type="protein sequence ID" value="ERG88576"/>
        <property type="gene ID" value="J07HX5_00722"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1829290_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="140" mass="15328" checksum="A78178C72B18E0FB" modified="2013-11-13" version="1" fragment="single">TTLCMFMQQALSTQTSPPESPTNATDDRPDLDVSATELLELLGDEYTHQVLEAVLERPRTGRELVEATNVSKATVYRRLDRLQAAGIVDARLKLDTDGHHRKQFHTTAESIQVGLGPDGLAASVEFGDDSRPRGVSHSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>U1P903</accession>
    <name>U1P903_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Valine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Valyl-tRNA synthetase</fullName>
            <shortName evidence="6">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">valS</name>
        <name evidence="11" type="ORF">J07HX5_00762</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88616">
        <property type="protein sequence ID" value="ERG88616"/>
        <property type="gene ID" value="J07HX5_00762"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02005">
        <property type="entry name" value="Val_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022874">
        <property type="entry name" value="Valine-tRNA_ligase_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="31"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="673"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="6">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="6">
        <location>
            <begin position="591"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="927" mass="104805" checksum="BC83DA5925A374C4" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P909</accession>
    <name>U1P909_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_tran_28_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00767</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88621">
        <property type="protein sequence ID" value="ERG88621"/>
        <property type="gene ID" value="J07HX5_00767"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059497_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="390" mass="41357" checksum="5D052D810579EC69" modified="2013-11-13" version="1">MCCHRLPSAGGYVVTNRRRLAATGGRDTRGVCSVYGYVLPDFKSHLFDDLVDQQIMGTGTAGTRHAHTRPGGPTVAVAHGCEGAGHATRMLAVAKGLEAAGYAVPLAGGGPGARFIRRNGYEEFEPTSVDFIGDYQRDNGLRAMLTGSVPATVARVREYRAWLAAIDPDLFVTDDVTAALAATLARRRYVYISHDTREFYTTPVEQAGAWLRNLIARVTATAYLLPKVWSGEPTIPDATAVLPLAPRADGAKDTVDVLIVPSAFSVSAEQVTAAIEARGRTVTLVGGEDWEIVPSLQPYIAGANLVVCSGYSTVMESAVAGTPCVVVPSTSEQRGVAATVAERRGFYSAHSIEALGALLDRDRIVAPDPQENGVDRVVAVVKRLLSPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P918</accession>
    <name>U1P918_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00777</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88631">
        <property type="protein sequence ID" value="ERG88631"/>
        <property type="gene ID" value="J07HX5_00777"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1064042_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="29012" checksum="C646DFF6B2D0D043" modified="2013-11-13" version="1">MKLIERGAGSPRVAVVGGIHGDEPAGERIVSRLIDTLEVSHGTVQLLLANERALATKTRFTDTDLNRSFPGDPRSEEYEPALAARLLDVLDGADAILALHTSQSAPPPFAIYSHLTESVRRTVTGLPVDYVVDAGDLRTTTLDSTLPHTVSFETGHQQSEEAAEFGYQATKAFLRAHGVLTDAEPTYTATQTVRAREEVPKGGGEPHLNYSNFEEITPGSVFAYDDVHTHRVENQGLVPVLASEDGYEDIFGIYGTFEEIIEPVPGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9C6</accession>
    <name>U1P9C6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (Chain I)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00887</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88741">
        <property type="protein sequence ID" value="ERG88741"/>
        <property type="gene ID" value="J07HX5_00887"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067218_4_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="149" mass="16636" checksum="A603C50970651F4D" modified="2013-11-13" version="1">MATTMKHALAGETVTVRYPDEAAEVSARFRGVHTHNQQRCLWCRQCETVCPTDTIQIVTDDEGTGEQFDLNVGQCMYCRLCEEVCPVDALVLTRNFEVTGDTADELVYDMDDLDAVSWYGDTDPLAAREPAREAWLAEGDDDSAVDYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9L2</accession>
    <name>U1P9L2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00957</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88811">
        <property type="protein sequence ID" value="ERG88811"/>
        <property type="gene ID" value="J07HX5_00957"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_16_6_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="2">
        <location>
            <begin position="164"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="28523" checksum="732BDBBBC451E54E" modified="2013-11-13" version="1" fragment="single">MRDDLDALGDAASKLWNVARWTVDRVWDATGEIPDVGPLKAYMKTRHCWKNLNSQSSQAVIEELSDAFQSWFDVRHKDETANPPGYRKEYDTRPRSTVTFKEDGFKVDTKHDQIRLSKGENLKDGWGDFVLCEYETRNDIDLNEVDTVQNVRAVWNGDEWTVHFVCKETVEMPDSPGDGVAGVDLGVSNIAAVAFPEEYVLYPGNTIKQDNHYFQQQEYDTKGENGLSQEAQRLRQKRNRRETHFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9N0</accession>
    <name>U1P9N0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyhypusine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00972</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88826">
        <property type="protein sequence ID" value="ERG88826"/>
        <property type="gene ID" value="J07HX5_00972"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039781_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="333" mass="35460" checksum="C8C77AE8E5E4B30A" modified="2013-11-13" version="1">MHDDREEFSHDPVTHAAVQAGMSVDELVEEYSAAGVGAAQLSDAVEVYAEMLANDDVSIFFGLAGAMVPAGMRRIVAELIRDGHIDVLVTTGANLTHDAIEAIGGKHHHGRDSAPDRTQRDHDEQLREEGVDRIYNVYLPQEHFTAFEHHLREEVFPALTGDEAVSIQQLTAELGRANAAVNERAAVDEAPGIAAAAAANDVPIYCPAIQDSVLGLQAWMYSQRAALTVDAFADMTGLNDIAHATDRTGAVVVGGGVPKNFVLQTMLVTPGAYDYAVQLTMDPPETGGLSGASLEEARSWGKLAPSARNASVYADATLTLPLLVAAARERIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA11</accession>
    <name>U1PA11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type antimicrobial peptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01083</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88936">
        <property type="protein sequence ID" value="ERG88936"/>
        <property type="gene ID" value="J07HX5_01083"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="26203" checksum="F161FD345243389A" modified="2013-11-13" version="1">MTTEPQQDPTPVVAATDLRRTYQLGEPVHALDGVSLTLPEGSFTAVMGPSGSGKSTLMNLVGCLDTPDEGSIAVDGQTVGALSATERAYLRGTTIGFVFQQFNLMPRLTAVENVALPLVFTNDTGADRHDRARSLLKQVGLGDRLTHTPAELSGGQRQRVAIARALANEPTLLLADEPTGNLDTETGGQIMSLVQELNDAGRTILMVTHERYVAAHADRIVHILDGQIEEIESVADEAPTLKTGGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAK2</accession>
    <name>U1PAK2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01279</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89126">
        <property type="protein sequence ID" value="ERG89126"/>
        <property type="gene ID" value="J07HX5_01279"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027187_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="661" mass="70939" checksum="48EB9FD780E9DF87" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAY1</accession>
    <name>U1PAY1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="2">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="2" type="primary">folD</name>
        <name evidence="5" type="ORF">J07HX5_01407</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="2"/>
    <dbReference type="EC" id="3.5.4.9" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89251">
        <property type="protein sequence ID" value="ERG89251"/>
        <property type="gene ID" value="J07HX5_01407"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034045_1_2_2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="3">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="4">
        <location>
            <begin position="122"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="299" mass="31649" checksum="A44EC3D17DD42E1C" modified="2013-11-13" version="1">MAAIIDGEAVAATLRAELQACVDTLIEADNRPRLATVLMSTDPASETYVEMKQQDCEELGIAADDITLAADAPASTLFETVDELNADPAVNGVLVQAPVPDHVDYRQVIEQIAPLKDVDAFHPENVGRLVAGYPRYKPCTPHGIQRLLRAVDADPAGQHAVVVGRSRIVGKPVANLLLQKATGGNATTTVCHSRTADLSAQTQQADILIAAAGRPELVDGSMLSEDVVVIDVGINRVEADTEKGYELVGDVAFESARKKARAITPVPGGVGPMTRAMLLYNTVKATSLQADADVEIELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB82</accession>
    <name>U1PB82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01494</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89336">
        <property type="protein sequence ID" value="ERG89336"/>
        <property type="gene ID" value="J07HX5_01494"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544152_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="173" mass="17777" checksum="BB499455067F66C5" modified="2013-11-13" version="1">MQAPGGKEVPGILIAALLLMIGAGAAAGAATGAINGDSSTEVEQALSIDKVNVDDGNGFGVIGDDETSFVTSAELVQGDEYEIDVDLENGGSDITAKLVFENTDPLHIDVSGEAGIEVGQVGDNEFLLEIEDFVDDGNDAGADEITITVSSSNSIQPGFFEFETKIVPVEPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBQ4</accession>
    <name>U1PBQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01671</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89506">
        <property type="protein sequence ID" value="ERG89506"/>
        <property type="gene ID" value="J07HX5_01671"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="31254" checksum="9F95552F24D3FC83" modified="2013-11-13" version="1">MPGTVVVTGADSAIGRATADTFLTAGWTVYATSHDEAELTDLAEAGCQTAALDVTDPAAVERVVDRIGAEAGAIDCLVIATGTRQYGPLEDVPPDRLHDQFAATVYGPHRLIQAALPNMRRAETGTIVTVSSVYGRIAAPGVGPYAASNAALEALSDSLRAELDGLGIDVVVVVPGPTGTNTDNRTVDGTAGLDQTRAYEWVYETLSDAALTTGALPGTTDPATVATTIHDAXXXXXXXLVSTACDRGPPQVQLWESISRVLLGLLRIVYREPPALLSVSRQDELNWVVTQTGHQQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC27</accession>
    <name>U1PC27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01811</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89641">
        <property type="protein sequence ID" value="ERG89641"/>
        <property type="gene ID" value="J07HX5_01811"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3130710_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5453" checksum="D67806B8FBDB7EE5" modified="2013-11-13" version="1">MTPVPYESGDQPTDELPELVCPRCGGTLRRYRQATACLDCNYVPRHGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCD8</accession>
    <name>U1PCD8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01928</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89756">
        <property type="protein sequence ID" value="ERG89756"/>
        <property type="gene ID" value="J07HX5_01928"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754627_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="148" mass="16785" checksum="2A10C474A577BAF4" modified="2013-11-13" version="1">MHYTYRYRLKPTDAHHKQLDYWRDTCRQLYNHALNEFSEIPNSERTLNQRVRQVRDQLPDLKDWGDDLNDLYSTVTQAAVMRIEDSVSALSQLKKPATTLAVSTGKPPASPAASLTYREASSSIVRRSDCTFPVEARGYSSSATSRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCU4</accession>
    <name>U1PCU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_02079</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89906">
        <property type="protein sequence ID" value="ERG89906"/>
        <property type="gene ID" value="J07HX5_02079"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012821_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039263">
        <property type="entry name" value="GTPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="PTHR43721:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="121"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="532" mass="57525" checksum="96B4FB25432F4BF4" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFM6</accession>
    <name>U1MFM6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00080</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87939">
        <property type="protein sequence ID" value="ERG87939"/>
        <property type="gene ID" value="J07HX5_00080"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2461650_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="9428" checksum="AF5ED13521DE2805" modified="2013-11-13" version="1">MIFCGGVSMSVVPQPNNSTGFETTSTSWYDIVLCAVPVIFFLSVLIGTHAAVPIRSSVGIGAVLNAGLFIDVLFVHPPVEHKSDEMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFT8</accession>
    <name>U1MFT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD superfamily phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00170</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88029">
        <property type="protein sequence ID" value="ERG88029"/>
        <property type="gene ID" value="J07HX5_00170"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026821_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="56"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="389" mass="43234" checksum="FAF6EB2A515683CD" modified="2013-11-13" version="1">MVRFQPADRIRDPIHGNIPVSKLEKRLIDTDVMQRLRRIRQVSLSSLVFPGATHTRFSHSLGVMYLAGELADSIGMSDSEYRTVRIAGLLHDIGHGPFSHASGDIAESFGRTHEERSCELIREELAGILPGAIEIGRIEEYIHGDATVNIVAGEIDADRMDYLLRDATFTGIDHGEIEYETIVEFAELAGGELAFNRQAVYSLTSLLTARLYMHLEVNDHRSTRLAEAMLRRVLREYVERNGVEAMMEKDDYSMHAELMEMGGPCETLYQRIQRRDLLKPAYTIQGDSVSEETVSTLATLDPVTCEQEIAEEAGVSIDAVVAVRPAPPSESTLSVTICDNGETKPLADVSAIPRQLTAERVRSARFDVYTNESNEQAVRDAARSVLAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFX6</accession>
    <name>U1MFX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein UspA related nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00221</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88079">
        <property type="protein sequence ID" value="ERG88079"/>
        <property type="gene ID" value="J07HX5_00221"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_11_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="14949" checksum="159AEE87C3EDB7A6" modified="2013-11-13" version="1">MAEAERVLVPVDGSEPSEQAVTLAASLFPGVTLVLLQVINPAETGYSIDATIPTFPEGWYDDAVERAEQTLERLAATVDAETEQTTAVGKAASVTVEHAEQNNIDHIVMGSHGRQGVSRILLGSVAESVMRRAPVPVTVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH08</accession>
    <name>U1MH08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00695</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88549">
        <property type="protein sequence ID" value="ERG88549"/>
        <property type="gene ID" value="J07HX5_00695"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098519_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="232" mass="24165" checksum="36140375F4C5BE31" modified="2013-11-13" version="1">MPVADAQINFLLGTARVNAALGWLLVGIIGSVAVASALAGDPIWAGFAAAVGALAIVPAVAFRSWRVMLPWEVLVLASFPIIGRLATAVELNNKLATYLSVAALALIIAVEIHAFTGVRMTPTFAVAFVVVATMATVGIWAVVRYALDVALGTTFLIDPDLTDAAIEREVMLEFVASTVAGLVAGVVFELYVRRRAVPDPVVAGPRQSSSPSGETASAGDPGQDEAKRGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH17</accession>
    <name>U1MH17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00710</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88564">
        <property type="protein sequence ID" value="ERG88564"/>
        <property type="gene ID" value="J07HX5_00710"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_629476_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="1">
        <location>
            <begin position="34"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="430" mass="46873" checksum="44605ABA1C89217E" modified="2013-11-13" version="1">MTRRHDRAFVRTFFTSPTAVEGDNSAKMLNRAAELRGMQAPDVWVPDNEDATAPGMREEGVANIIDVVAKHGADVPAEIHPRVVWHRDNASTRASGFEQIRRIADSPAAPYIDGFVIPEVGGLDDWKKADELMTLAESEAGLPTGTFAMSVIVESATAELALADLRETLHQPSNALERLFLLVDGEVDYTKDQRAITPTGALPEWPELRHNTARGASAANLIAVDGPYDDIRDMEGYRERMVDNQARGQLGIWALTPSQVVAANKEPLPPATGEWLLELDGDSVSLTPDESGDVYAYEGDRLSLTTTDDGYQLQVGGETHQLDATALRETITERTAYVPSLSDIVDSMEEFEAAKAAGQGAISMERAATLELDGVTVEISKDRMWDEATYQAATTPIDLFQDVHDARPDQHDALADRYGAEVVDRATQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH43</accession>
    <name>U1MH43_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00745</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88599">
        <property type="protein sequence ID" value="ERG88599"/>
        <property type="gene ID" value="J07HX5_00745"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3413618_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="28" mass="3164" checksum="C07C1BD3A086EB29" modified="2013-11-13" version="1" fragment="single">MPPETLVVDTDLARVTRFDDSAVIHHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH82</accession>
    <name>U1MH82_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00805</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88659">
        <property type="protein sequence ID" value="ERG88659"/>
        <property type="gene ID" value="J07HX5_00805"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1665441_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043850">
        <property type="entry name" value="DUF5812"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19129">
        <property type="entry name" value="DUF5812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="17572" checksum="E88A83D0C0F0202E" modified="2013-11-13" version="1">MALCISAMAGSNTAEEVTGRFVVVEADESVVLRSVGSGQVFTLSNNPGVESTAVLDATLVPQQPLGLTHTVASIEAARTVPVRLSADPPSDPAQSAGASLAPGESAAPGHPDGGVLHVIGVAPDSAAARARALKEDDSLRVTAARHGLFTVELRWSESSGFVTVRYFHSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHB5</accession>
    <name>U1MHB5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00850</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88704">
        <property type="protein sequence ID" value="ERG88704"/>
        <property type="gene ID" value="J07HX5_00850"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006855_3_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="47272" checksum="AC12A639E8A9550D" modified="2013-11-13" version="1">MSSAGISREQWSTRAGFVLAAVGSAVGLGNIWRFPFVAAESGGAEFLLVYILFICLVGLPAILTEFVVGRKTGRNPVSALQEIGSGLWRYLGWLFVLTTFVVMSYYSVVAGWTVRYALLGLEGQYAASMSGAEQQFLQVGQGIQTVGFHALFLVLVFGIVDLGVQRGIELAAKLMVPVIVLILIGLAGWATTLEGASEAYSFYLSPELGAVTAHWTSIVPSAAGQAFFTLSLGFGVMLVYSSYLGEDRNLVTDGSIILGLDTVVAVTVGLIIFPVLFTGGTPPGGQGVEVLFTSLSSAFGGLSAGGAIGAVFFATVAIAALSSAISLIEVIVSYLVDERGIPRRRATGAICGALFVFGIAPAVDTDLLELYDGFADGVLVVLGGLLFTAYVSWMWADEAAEELSHGITNSNSGRLSRCWIWLVRVPVVTVLVVSLVLGVAEVWGECPHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHK1</accession>
    <name>U1MHK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00945</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88799">
        <property type="protein sequence ID" value="ERG88799"/>
        <property type="gene ID" value="J07HX5_00945"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2854642_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="6828" checksum="967470314829DDF3" modified="2013-11-13" version="1" fragment="single">MNAGKLLKYLLAGALAWVVLSTVVSVVFTALALLWSLLVAAASVLVLAVVVYGLYSLYQSVSGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHL7</accession>
    <name>U1MHL7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate dehydrogenase, hydrophobic anchor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00965</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88819">
        <property type="protein sequence ID" value="ERG88819"/>
        <property type="gene ID" value="J07HX5_00965"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2353117_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="10713" checksum="3D6FF6E5E34CB06E" modified="2013-11-13" version="1">MTRSSFTPGTWRWLLQRVTAVFLLGALAFHMVSIHGLNHASESSFMQSQQRMSQVGYFAFIWVFLLTATVHGVTGVCTTLVNLGLPAEPARSWPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI39</accession>
    <name>U1MI39_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gas vesicle protein G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01169</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89019">
        <property type="protein sequence ID" value="ERG89019"/>
        <property type="gene ID" value="J07HX5_01169"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185764_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="10004" checksum="DC982F69C4BB71B6" modified="2013-11-13" version="1">MLIVDDLLIKPFFSMLDILHKMALDEMYDIEVLRDELKENQLLYEIGERSETEYQQRKNRLQTQVEIAEQIRARMQGRFEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIR6</accession>
    <name>U1MIR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01477</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89319"/>
        <property type="gene ID" value="J07HX5_01477"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="2">
        <location>
            <begin position="68"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="37833" checksum="AE967A61AC1644A9" modified="2013-11-13" version="1">MTTTATTTPAVRYECPACEQQYAPTEAWRCCCGRPLEFVDRPELSDELDRTRGVWAGGLPPVGPRARLGAGWTPLVAGPHTAVSYKLEGVNPTGSFKDRGAAVTISLADALGVDRVCEDSSGNAGTAIATYAARAGIDAEIYVPADADSGKLRAIERTGAKLVRVEGSRQQATAACHDAVAAGRGWYASHAWQPAFLTGTASIAGEIYAQLGGVPDAVVVPTGHGTLLLGLYRGFQALQAAGKTADADIGTDTLPRLYAAQAAGTAPVVAAHHDSNAAAGDNNLADGIQVREPARGEQIRAAVTNTGGTALAIGADATRRHRDRLRKAGISIEPTCAVAPAALAALRDRGEIGPEESVVVPLTGRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ61</accession>
    <name>U1MJ61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydroorotate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01650</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89489">
        <property type="protein sequence ID" value="ERG89489"/>
        <property type="gene ID" value="J07HX5_01650"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2340036_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="97" mass="10730" checksum="488C3DD39A891146" modified="2013-11-13" version="1">MLQTRDALTDILGTVADAGARPLLMKLSPNLPPLAVDDALAVARELELDGIVTTNTTTDQHRCNHRPVPRLVDCRASHSRNTPRRWYAMSPSTLICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJY0</accession>
    <name>U1MJY0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01986</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89814">
        <property type="protein sequence ID" value="ERG89814"/>
        <property type="gene ID" value="J07HX5_01986"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1412400_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="21057" checksum="A87BCE97556C9CAA" modified="2013-11-13" version="1">MEYQLSIEDTPSTIPAGTGLLLVHPSTGQTDRIDTDFLKTDTDHILVVSTRTTAREVQQKLEHYEVDESKATILDALSVERGYTRRQSDHVKYVSAPADVEAIVDQTREFLTTHDGKLRISVDSVTEMSYYAGQDQAMTAVEQLLGLLAEYDAVGLFHIARGVYDEAALAGFKALFDGVVELAEDGSVTSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK40</accession>
    <name>U1MK40_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bile_Hydr_Trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02067</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89894">
        <property type="protein sequence ID" value="ERG89894"/>
        <property type="gene ID" value="J07HX5_02067"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1380614_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006862">
        <property type="entry name" value="Thio_Ohase/aa_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042490">
        <property type="entry name" value="Thio_Ohase/BAAT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04775">
        <property type="entry name" value="Bile_Hydr_Trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bile_Hydr_Trans" evidence="2">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="198" mass="20518" checksum="E772114CB184D44E" modified="2013-11-13" version="1" fragment="single">MSKRTRREWLCLVGVASAGIGGLAGCSSSGTEGTDSSPTDASQSTRTATLADENNTETPATTATETPSEQDLSFEHPEEVLVDEPLGMTINGLPANTAVNIHLGEPEQATTTATVKTDDEGQVDLSDANVVGGDVPTDLSVPLPVALLQFGDLPDTTGQTQSVTYGGSADSTGLGSTTVTRQLPPDKPDQELQRDEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK47</accession>
    <name>U1MK47_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02082</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89909">
        <property type="protein sequence ID" value="ERG89909"/>
        <property type="gene ID" value="J07HX5_02082"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202923_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7252" checksum="62B66835337A0FCC" modified="2013-11-13" version="1">MIGMSVASSCEICRTAGVSDTCVRCSQLVCTEHFDDETGQCAACVAETGSGGSDTPTNIPTGDETDLLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK61</accession>
    <name>U1MK61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02102</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89929">
        <property type="protein sequence ID" value="ERG89929"/>
        <property type="gene ID" value="J07HX5_02102"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2712703_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="7954" checksum="88E69C263A214CFA" modified="2013-11-13" version="1">MGLLSTIGEVFKASTQSTNRGDVTQNNSEGAFWCHDCQERIRDVDVEGEGTPDCPSCGDAMEFERSKGTSSCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK64</accession>
    <name>U1MK64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02107</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89934">
        <property type="protein sequence ID" value="ERG89934"/>
        <property type="gene ID" value="J07HX5_02107"/>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
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        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="281" mass="29335" checksum="A11FEFD156402B97" modified="2013-11-13" version="1">MSPYQKYLLADSSETTVLFVRDTVALALFVPTVAFLLFSQGFSGSPRGILAMLLTGVLNVIGAFVVFRALNREDASVVVPLTSLSPVVTSLAEPLLRSTVVPPVVAAGGVLSAVGAAVVSSEQNTLESLVRSPDTEAVVLAVSANFVFGLTTILDGIATTTVNPLYVSSVIILSVCVGSGLRLRTQTWAQTGIEAAEQRAQLRRLIRRDKGVLGCIQFVGLGATLTAISVAPSATQALILFKSNIILVVLVSTTRLHEGHRLRRTLGAAVIAVGTVLAVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK89</accession>
    <name>U1MK89_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_02147</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89974.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89974">
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    <dbReference type="Proteomes" id="UP000053694">
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        <property type="entry name" value="DUF6432"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="97" mass="10972" checksum="DBE986879E393F0A" modified="2013-11-13" version="1">MRAKPEYRDRSDVEVAVLDALAERHTEGMTVFELRAEVEAGIDEIEPALERLKGDMLIEATNDGGRTVVVPKDHAIGPSEHDEDDDVFDRLRQRLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV02</accession>
    <name>U1MV02_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diketogulonate related aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00031</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87890">
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        <property type="gene ID" value="J07HX5_00031"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_12_0_2"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
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        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="184" mass="20207" checksum="7DD78EFD373035EC" modified="2013-11-13" version="1">MTVNESWVTTTAPVXXXXXXXEYEPAATLGALEAVFEAGLTRRIGVSNFEPDHLDRARELCDVPVFANQIEIHPYLPQETLRDYADRTEIELVAYSPLARGAVLDDPTLTAIAADHDTSAAQVALAWLRSLGITAIPKATSRAHIRDNWASLTVDLSAEEIARINAIERTDRRVHPDFAPAAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV26</accession>
    <name>U1MV26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87925">
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        <property type="gene ID" value="J07HX5_00066"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089552_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="187" mass="21029" checksum="FD61F714DC8B45A4" modified="2013-11-13" version="1">MAEDPLSEEVIEQATQLTRWARRAAQPAATTYRERRAELVAAHGYTARVRESETNVLVLYPEEWVVDGTVRRDRIDDLDRGVERPLSGDTPDEDWEHVWAHNCDLADTVETSHGPVHGANAQALAEFASNHYAARIERLSSEALHEFVIEYFPRNAWPSADQKAVVEKSVRLTFVTAGEPEPTIGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV40</accession>
    <name>U1MV40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00086</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87945">
        <property type="protein sequence ID" value="ERG87945"/>
        <property type="gene ID" value="J07HX5_00086"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="279" mass="28421" checksum="99E9CBAF151B0E27" modified="2013-11-13" version="1">MSVAYTLVLNAAVATLVLALAAVGLAVIFGMMNVINLAHGAFITGGAYVAWVAANAGSFWAGVIAAPIVLGVVGYVLEWAVVGRLYDRPLDTILATWGIALAAQEGLKLLFDATSKDVPLPIQGRVDLGATVYPTYRLVLIGMSAVVLTAVFAVLLSTKFGVRLRAVIQDPTAASLLGLNETRLYRITFASGAGLAGLAGAVLSPIATVTPEMGTTYLIDSFLAVIIGGSPVGVVLGSAVVAGTGNLLSFAVSPVTAQTVVFVVAIAVVVVRPEGIVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVD0</accession>
    <name>U1MVD0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00054</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87913">
        <property type="protein sequence ID" value="ERG87913"/>
        <property type="gene ID" value="J07HX5_00054"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133053_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="16281" checksum="22F597F12BAD4025" modified="2013-11-13" version="1">MAPALLVPAAWTATGAVHADVMSEDGLFIAHFVMAGFIAVFAVSGWRSMSTGALRTWRTVLVVGLGLTLAGIGGFVTATDTLQAISIVGWMLLPAAGLADTGRRLADGAGLYYAGAAIAVLGGVIYLGAVGAVDGGLPLELIGIATVGIGQTAGILEASLRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWD9</accession>
    <name>U1MWD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tryptophanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00575</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-eliminating lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88430">
        <property type="protein sequence ID" value="ERG88430"/>
        <property type="gene ID" value="J07HX5_00575"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047223_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011166">
        <property type="entry name" value="Beta-eliminating_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001386">
        <property type="entry name" value="Trpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="4">
        <location>
            <begin position="57"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="441" mass="48064" checksum="230D9336575A3EA0" modified="2013-11-13" version="1" fragment="single">MSSNRVFTVVYISYVVTTYKSKVVEQIELPTRQQRAALIEDAGYNLFNLDAADVFVDLLTDSGTGAMSDEQWAAVLRGDESYAGSSSFRRLEDAVVDVMGFDYVVPAHQGRGAENILYGSLLSAGDVVLNNTHFDTTRAHVVNQDARAVNCPVPAASEIDSLDDFKGNFSLPAGREAVAKVGAASVPAVILTVTNNSGAGQPVSVANTRQLRAFCDEIDATLIIDACRFAENAYFVAQREPEFADATIAEIAREQLSYADAVVMSGKKDGLANAGGFVACDDPELHEQVKQRGILYEGFSTYGGMSGRDIEAMAVGLREAVERAYIEDRVSQVQSLGHRLHDHGIPVYRPIGGHAVYIDAGAFLPHVPDAEFPGQALAVELYREGGVRTVELGSFAFPDNDQLELVRMALPRRRYHQEHIDHVVDTVVDVWQRRSEVGGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWS5</accession>
    <name>U1MWS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain amino acid ABC-type transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00746</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88600">
        <property type="protein sequence ID" value="ERG88600"/>
        <property type="gene ID" value="J07HX5_00746"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="360" mass="37814" checksum="18F25371C831EEEB" modified="2013-11-13" version="1">MTGLALAALAPVDVPSAVGSGGVPLSTGAVVDLFSSPTDLASVLVEGLAKASLYLMIASGLTLIFGLMDVINFAHGAFTMFGAYISGAAVLTLGVGSTGLVGSVGTFALLLVGVFVLLAVLGVVLEVALVRRLYDYPPIFMILLTFGISITMEEFMRIVVDYFEVNSAREAVDWSIPRQETVPEELQGTFDVAGVSIGGLHPLQILLGVLTVVGIWYFLNRTRYGLFVRAGVEDDEMATALGINIKRTFTVVFAIGSGLAGAAGVMLMWSPLWQVNVPLALGVLLPAFVIVIVGGLGSFKGTVVASLLVGLLDAFATWAFRVEVVTFTDIDQLLIFAILVVMLVLQPRGLFGVEGQGDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX00</accession>
    <name>U1MX00_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLUG domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00654</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88508">
        <property type="protein sequence ID" value="ERG88508"/>
        <property type="gene ID" value="J07HX5_00654"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1499271_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011493">
        <property type="entry name" value="GLUG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07581">
        <property type="entry name" value="Glug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glug" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="18528" checksum="1016396AD7870EC0" modified="2013-11-13" version="1" fragment="single">MFLGESEKTGSLRRRLRTAVAVGVAVALLCGVTLAVGGLGTGSVAAQSQGPIEISTWTDLADVRDDLNADYVLVNDLDQETMGYESVAGPTANNGRGFNPIGEVRNEFVGSFDGQGNTIRDLIIDRPTEDFVGLFSISSGAIENAAVVNATVTGNFRVGGLVGFNLANVSNSEASGSVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX27</accession>
    <name>U1MX27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00846</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88700">
        <property type="protein sequence ID" value="ERG88700"/>
        <property type="gene ID" value="J07HX5_00846"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3000683_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="5824" checksum="B22B2390E720EF70" modified="2013-11-13" version="1" fragment="single">MTEAIQAFPSQAFYDGALCPATEGLRGQSPATVSGVTQTALPAGLRGPVSFVDPDGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX48</accession>
    <name>U1MX48_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00704</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88558">
        <property type="protein sequence ID" value="ERG88558"/>
        <property type="gene ID" value="J07HX5_00704"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3161268_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5476" checksum="3BA2C2FD4247D0FC" modified="2013-11-13" version="1" fragment="single">MLEGDDAHLDILKTALESEEWKTGTAEALFYNGNAELHVNVTNTEQTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXF1</accession>
    <name>U1MXF1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00819</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88673">
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        <property type="gene ID" value="J07HX5_00819"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="54"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="27857" checksum="97EC034A7030324B" modified="2013-11-13" version="1">MRAERVKGEEWYQADDVAEAYDEKRFSRGGRLIDRREKRAVIDALSPLDNKQILEIACGTGRFTTLLADRGANIVGVDISDPMLQQARERAQMTGVADNLTYFRGDAARLPFDDGQFDAVLAMRFFHLCDTPVEFMTELSRVSRGQVVFDTFNRFSTRSLYNWALPMGSRLYGQQQVSKLLEAAGLELADAEHDWMLPYGFYRKLPTTAASAFRRLETGLDAAPATSYLASVSYWNAQRQPELASNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXJ1</accession>
    <name>U1MXJ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00869</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88723">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2008573_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
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        <property type="entry name" value="SSF89550"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="13117" checksum="ED31633F2544C111" modified="2013-11-13" version="1" fragment="single">LTPTEAVALAHDRGCAAVIAHPFRRSSVADSGAAFDAVELNGKRPERRARVRSLAKKLDVPVVGGSDAHIPVAVGRAATRIRVEQPTPAAVVAAIQRGDVTPVVRSTPVDWMMQRCYRAYHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXJ5</accession>
    <name>U1MXJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00874</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88728">
        <property type="protein sequence ID" value="ERG88728"/>
        <property type="gene ID" value="J07HX5_00874"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2031395_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13519" checksum="55581552442DBB6F" modified="2013-11-13" version="1" fragment="single">MPRAVRAGFEWHPDGDRLFFHRDEAGDEQHDIHAIDLDGETEPVVEMDGQCILGAVGEDGETLVFSSNAGGQLNLYRHDLPSGETTKLTDYERATVAAQLSPDCETLAYTTNETDDYDNMDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXR4</accession>
    <name>U1MXR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00944</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88798">
        <property type="protein sequence ID" value="ERG88798"/>
        <property type="gene ID" value="J07HX5_00944"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1258401_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23824" checksum="9DA3ACE257355B67" modified="2013-11-13" version="1" fragment="single">MQVSTVLSSTPGESIGAGMLLLLVLLALSSPIAYGGWKNKQRYHELSTISDDLAAATPGECVSVSGTISRRSQQVRSPYQSQSCAVALWDIAQFSGDRRGWETKAIGIIAGELQLRTDDGQVVVSGLSREKTLTATEMVKRLLTTDGSSAIASVQIELGRSSTERRFRPSQEPPEPYRTQAKTAGIDIPIAEPPGRLKRALSTLRTPADTTRYRESVFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXX9</accession>
    <name>U1MXX9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00999</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88853">
        <property type="protein sequence ID" value="ERG88853"/>
        <property type="gene ID" value="J07HX5_00999"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_4_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="16762" checksum="484A549B43AEE061" modified="2013-11-13" version="1">MTYEHLDRELVNALLGDGRASLRSLADRLNVSVTTVSNHLAELEDQGTIRGYRPVLDYSTMGYDVTAVLQLNIDGKAIVDVTERLADQPQIISVYEVTGDHDIVAIGKFTDTEEMNARIKDLLTTPEIKESNTSVVLNPEKEHEQFMLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY31</accession>
    <name>U1MY31_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01064</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88918">
        <property type="protein sequence ID" value="ERG88918"/>
        <property type="gene ID" value="J07HX5_01064"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504833_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9001" checksum="4297765C56247B3D" modified="2013-11-13" version="1">MSNTTTDDSTAWDGDDLLYLIGGVMSAAVAVMFLIVALILTPIFGFAAVFFGYQLYKMEGRTKSAIAVVLSGLLPTVLAVLNPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY60</accession>
    <name>U1MY60_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01101</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88953">
        <property type="protein sequence ID" value="ERG88953"/>
        <property type="gene ID" value="J07HX5_01101"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="120"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23662" checksum="543E7B59AA4B3B2B" modified="2013-11-13" version="1">MSTDEYRDQLARLRSEVGATADLVCDRYASAVTVLASGDASAAERVIDGDRELNDWYLDIEVDCLGLLALYQPVAGNLRLIVAAFKIVTDLERIGDLATNLASYGQQAGGQLPAVADVPSVAETAGSLVADAAGAFTKRDAERARAVAARDEALDQACQRQSETVARALVTDRPDAADQRLKRATRALLAIRDIERVGDHAVNICARTVYLVENDPELIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY71</accession>
    <name>U1MY71_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argS</name>
        <name evidence="12" type="ORF">J07HX5_01272</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89120">
        <property type="protein sequence ID" value="ERG89120"/>
        <property type="gene ID" value="J07HX5_01272"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_6_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="468"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="592" mass="64619" checksum="AF1E7F679A6B678C" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYE6</accession>
    <name>U1MYE6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01194</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89043">
        <property type="protein sequence ID" value="ERG89043"/>
        <property type="gene ID" value="J07HX5_01194"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2091262_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="12066" checksum="558095506FBBEEF9" modified="2013-11-13" version="1">MGARPPPNDMGEEPDITEFGVAALDARIEEMDVSFPVTAVELRRQYGDVRVPVDPAGNEIQLGEVIAATDQREFTSETELQRALSPVFEQKRERVSSGIVGWLRSLLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYI3</accession>
    <name>U1MYI3_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01385</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89230">
        <property type="protein sequence ID" value="ERG89230"/>
        <property type="gene ID" value="J07HX5_01385"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3245214_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="5075" checksum="A85BC33B6C916ADD" modified="2013-11-13" version="1">MIMSWHLFSRTNKEKQRLYKQLRERVSGRVLLPTGETELRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ42</accession>
    <name>U1MZ42_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01604</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Archaeal flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the archaeal flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89445">
        <property type="protein sequence ID" value="ERG89445"/>
        <property type="gene ID" value="J07HX5_01604"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051124_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097589">
        <property type="term" value="C:archaeal-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35903">
        <property type="entry name" value="PTHR35903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01917">
        <property type="entry name" value="Arch_flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0974">Archaeal flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="19687" checksum="098A46BABCBCC623" modified="2013-11-13" version="1">MIPTLPDSDDRGQVGIGTLIIFIALVLVAAVAAGVLITTSGSLQSQAESTGEQTQSEVSNAVDVVTATGNANGDAVANVTLTVKKGPGSESVDLNDSTIQYTAANAEQALVHGSNASDTEFSTSSLTDGDAEVLSNTNERIEITIDLSSIENTDDGLLEDESATLEIIDQSGASTSFELNAPQVIDTDIVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB8</accession>
    <name>U1MZB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01716</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89550">
        <property type="protein sequence ID" value="ERG89550"/>
        <property type="gene ID" value="J07HX5_01716"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020822_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="5732" checksum="F202175025BC5E6B" modified="2013-11-13" version="1">MGLTGGLLMYIGLAFVSGVDQREDSEFGTSQLPRAVVGQPQKSSTLSTALSTKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZD9</accession>
    <name>U1MZD9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01561</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89403">
        <property type="protein sequence ID" value="ERG89403"/>
        <property type="gene ID" value="J07HX5_01561"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_58_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="222" mass="24422" checksum="788D73FBC64D4A8B" modified="2013-11-13" version="1" fragment="single">VLRDVSDQKAYEQGIEAQNERLTEFAGIVSHDLRNPLGVVEARLELAQQECETEHLDEASDALDRSQALIDDLLTLAQEGERVAELEPVALSDVIEQCWDGVETDHATLEVEEMPVINADRSRLRQLFENLYRNAVEHSGSNVTVRAGAMDNGFYVADTGPGIPESERAAVFEAGYSHKKEGTGFGLRIVEQVADAHDWDVAVTESAQEGARFEITGVKTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZE0</accession>
    <name>U1MZE0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01741</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89575">
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        <property type="gene ID" value="J07HX5_01741"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2783893_0_0_2"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="68" mass="7472" checksum="2D141D320AFC303F" modified="2013-11-13" version="1">MTRWSLAVSATAPTTLTSTDPRPDQIRSNQTKLDPTELNRTDRTRPDYTGSGRTSRGVGQCILPCPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZQ3</accession>
    <name>U1MZQ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01862</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89690">
        <property type="protein sequence ID" value="ERG89690"/>
        <property type="gene ID" value="J07HX5_01862"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078972_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043859">
        <property type="entry name" value="DUF5821"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19138">
        <property type="entry name" value="DUF5821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="271" mass="29612" checksum="ABA24340492FE39B" modified="2013-11-13" version="1">MERAESGLFDAGIVDTFGNVLEQTDNAFLVNPSRTVVEDVLADLTVDSEISVRLFVAEAALKTVVSEFVVASTLADLARTDVLSVRLLESVPRYSLLVTDTEVVSFVDYNGDMAGLATEADTFVAETYDEYERRWAAAERYMPQAPPISRIRETLEANLSEAVMADFDRALARVEDIGDRSPVGEVEVALLVAAKHDALLYDISQWGEKIGLASKATFSRTKNSLEQTDLVETEKVPIEIGRPRLRLSLGAEAPVDAAIETIVRTAADRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZV5</accession>
    <name>U1MZV5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="3">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01759</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89593">
        <property type="protein sequence ID" value="ERG89593"/>
        <property type="gene ID" value="J07HX5_01759"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060552_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="45"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="191" mass="21685" checksum="18FF544CA8E4D283" modified="2013-11-13" version="1">MTTRSDDPDTNTDHANAAQDVVAVNAAGDPQQTVNRLDAHTGDGIRHRAFTTLLFDTNGRVLLAQRSPEKRLWDTYWDGTVASHPAPEQDQTAAATERLEEELGVAPEQYERLAVTDQFEYKRYYYEAGVEYEVCTVLQATLTDTSLAPDPAEVGGIAWVPYDRLHDNPRWYSQLRLCPWFEIAMRRDHTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1N047</accession>
    <name>U1N047_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01997</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89825">
        <property type="protein sequence ID" value="ERG89825"/>
        <property type="gene ID" value="J07HX5_01997"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090664_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="2">
        <location>
            <begin position="65"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="183" mass="18859" checksum="4FD7A23F376777D8" modified="2013-11-13" version="1">MCADHIKALDSALGETATVHKTPADQGSALIEETVVGTAIGTPLPFEALSLGETSVATAFSPAALAAAETGVTPAELAISDYGTISLPGDAAGTELVSLYCRRHVAVVAASDIEPDMQAAYKQLQETVTKQAGQDNAETEPQRQTDSRSQVLATGPSATADMGRLVQGVHGPHDVHIVVVTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0C0</accession>
    <name>U1N0C0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01940</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89768">
        <property type="protein sequence ID" value="ERG89768"/>
        <property type="gene ID" value="J07HX5_01940"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2101894_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="13030" checksum="F812D9FB7A8F380A" modified="2013-11-13" version="1" fragment="single">MTNDPRDHEFSDGQGFDDPYEPFDLDPELATDIDAVDPVDSHVLADRLDQTHIAEGDVDGEQLLDVGLEYVQINRHEQATDTFERAARYATNDRVAQEAWVNKGVAHAELEEYDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0M8</accession>
    <name>U1N0M8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exopolyphosphatase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02030</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89858">
        <property type="protein sequence ID" value="ERG89858"/>
        <property type="gene ID" value="J07HX5_02030"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1139993_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="244" mass="25715" checksum="5604C7593149701A" modified="2013-11-13" version="1" fragment="single">MCAATTGLTMASLSTYAILGCGSVGHAVADELVSEGKEVLIVDEDDDRVETLRDQDMDARQARIETDAVADAVTDRDVVLILAAGEAPTVQAVEKLRDRSTDQYIVARGSDPVSADRIREAGADVVINPSSVIADSALRALESGELEYKAQQLVAVIAGTDRRLGIRLHRSPDPDAIASATALQAIADSHDVEADIHYDGEIGHQENRAFVNLLGIDLTPTAEPDQPADGTTAVLDSTPMTGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0U2</accession>
    <name>U1N0U2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02106</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89933">
        <property type="protein sequence ID" value="ERG89933"/>
        <property type="gene ID" value="J07HX5_02106"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893104_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6493" checksum="29AA6598E1962FC7" modified="2013-11-13" version="1">MGQFTIVVTIPVKDGPGKPSVFSLIGHFLDFNEKRRHVSTVGASSCYVGSTQVGLSGVSSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0U6</accession>
    <name>U1N0U6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenite-activated ATPase ArsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02111</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89938">
        <property type="protein sequence ID" value="ERG89938"/>
        <property type="gene ID" value="J07HX5_02111"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040761_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="35162" checksum="FB747475980EBB9B" modified="2013-11-13" version="1">MDRFVFFGGKGGVGKTTVSSAYAHKCATAGQEVLLVSTDPAHSTADVFDQEFDDEPQPVAGYDSLSAVEIDPQEAVDEHLMGIKRSLGDQVSPAIVNEIDRQIELAHRTPGAHEAALFDRFINVMQNAEAFDRVVFDTSPTGGTLRLLSLPEYLGGWINRLLEKREESVKLYERAAIGGREPQRTTVGDPIIARLQQRKENFEFAEVTLRTEASFFLVANPDQLSVRETARAIDQLREYELTIGGIVMNRLTPEPDPEENGRGARYLRDRIETERERLRTVHDSLEPPVVATIESRVREVKGDLLESVAAELDVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P318</accession>
    <name>U1P318_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NCAIR mutase (PurE)-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00003</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87862">
        <property type="protein sequence ID" value="ERG87862"/>
        <property type="gene ID" value="J07HX5_00003"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065705_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="120"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="26125" checksum="9D61B216871B59DD" modified="2013-11-13" version="1">MQETLEQLANGEISVETAEAQLSGYATTEAGRFDAAREQRREIPEAILAEDKTPAQTASLAATAVETTGRAVVTRTNQEAVDQIRTQIENEFPGASIESNRLARTTVVYADGVDRPATDATVGVVAAGTADQPAAAEAAVVARETGATIDRVSDVGVANLTRVVDQLDRLREADVLVVAAGREGALSTVVAGLVTSPVIGLPVSTGYGHAGDGEAALSGMIQSCTVLSTVNIDAGFVAGAQAGLISRAVGTAREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P365</accession>
    <name>U1P365_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">J07HX5_00068</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87927">
        <property type="protein sequence ID" value="ERG87927"/>
        <property type="gene ID" value="J07HX5_00068"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073198_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG87927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="178" mass="20512" checksum="5A1688E8486D9AEE" modified="2013-11-13" version="1">MTDLWRDLETGPNPPETIHAVVECLKGERNKYEYDKSVPGVVLDRVLHSTVHYPSDYGFIPRTYYDDDDPFDVLVLVADATFPGCVIEARPLALMRMDDDGEQDDKVIAVPTEDPRYDHMTDLADLPEQRRDEIAEFFETYKNLEPGKETDTLGWDDRQAALEAIEHAQEQYQREFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3L3</accession>
    <name>U1P3L3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00234</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88092">
        <property type="protein sequence ID" value="ERG88092"/>
        <property type="gene ID" value="J07HX5_00234"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490319_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9216" checksum="D4CA771B2AE32ACD" modified="2013-11-13" version="1">MIQSPPQSRHVSKNLANRQLSRLAVYAAVIPLIIAVLTVPAMVGAFVLGIVSTVGISRGRNRLSQARNTTDSDSKTRSLSSDREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P431</accession>
    <name>U1P431_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_00410</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88267">
        <property type="protein sequence ID" value="ERG88267"/>
        <property type="gene ID" value="J07HX5_00410"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_7_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="165"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="271"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="401"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG88267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="472" mass="48967" checksum="581C4F25662F326A" modified="2013-11-13" version="1">MTEISFGTDGWRARTSAVTRDRVQRIGRAIVAHLSETVGADGPVAVGYDARAQGAEYATAIAGTVTATGRPAVVATRDLPTPALAWTVAEGPYAGGVMVTASHNPPAYNGVKFIPANGAPAPLSVTDDIEARLPSSDTMGADDPGAGLTDEPTDAAVDRRDLRSTYIKAVLEFVETDLSGRTIAYDAMHGSGRGVVDRALTAAGATVRQVRCSRDPTFGGSAPNPGPDRVDDLRAVVEDGPADIGVVTDGDADRVGLVAPGVGYLGESLVLAVLYAFLLERDAEAEAGDVVRTVSTSSLVDGVAANAGQRVHETPVGFKWVAEAMAEHDVVLGGEESGGYGVSGHLQNKDGVIAAVLAAAADAEQPLAARVHELRSTHGPVMQDRISVACPDREKVATMETLAANPPTTVAGHAVTRTEQTDGLKLYLKEGWVLVRPSGTEPKLRVYAEASDSPTVERLLSAARERVAAVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4I6</accession>
    <name>U1P4I6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00557</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88412">
        <property type="protein sequence ID" value="ERG88412"/>
        <property type="gene ID" value="J07HX5_00557"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="314" mass="33193" checksum="841CDFDAA70F31D4" modified="2013-11-13" version="1">MATSWTTEQLPDCTDTTVLITGANSGLGFAATKAFAAKGATVIMACRSTDRGQQAATKISNAVGATGASLDVRLCDLASLESVASFTAGVNTEYDAIDMLCNNAGVMAIPRQETADGFEQQLGVNHLGHFALTGQLLDLLVETDGESRVVVHSSGAHEAGEVDFADLHREQSYDKWEAYGQSKLANLLFAYELQRRLDAAGITDLISLACHPGYAATNLQYRGPRQSGSTVRLGIMKFANTVVGQSAETGALPLLYAAAASGVEGGEYYGPGGLMNMRGAPEKQESNAASYDEDDAARLWERSEELTGVSYNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4J4</accession>
    <name>U1P4J4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00572</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88427">
        <property type="protein sequence ID" value="ERG88427"/>
        <property type="gene ID" value="J07HX5_00572"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3378197_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3682" checksum="BEC2292BBAC68BE3" modified="2013-11-13" version="1" fragment="single">ASRDMETVYTYEGTHDIHSLILGEDLTGIPAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4M1</accession>
    <name>U1P4M1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00607</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88462">
        <property type="protein sequence ID" value="ERG88462"/>
        <property type="gene ID" value="J07HX5_00607"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2579197_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="8670" checksum="8E715A903F0AC32B" modified="2013-11-13" version="1" fragment="single">AAKAHEAGTMGQLTAVDGGHRRCEIGVKTAAMYQKLSLEGVRVVDISANALTTELRLHLSTNLKVSAIIDLVRTRGPSMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4N8</accession>
    <name>U1P4N8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutamyl-and glutaminyl-tRNA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00627</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88482">
        <property type="protein sequence ID" value="ERG88482"/>
        <property type="gene ID" value="J07HX5_00627"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_1_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="7">
        <location>
            <begin position="2"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="8">
        <location>
            <begin position="310"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="483" mass="53772" checksum="6DD0240576ECE4D8" modified="2013-11-13" version="1">MRVAPNPNGPWHIGHARMGAVVGTYKQLYDGSFICRFDDTDPDTKRPDLAAYDAILDAIGYLGFEPDAVLRASDRLETYYDYAHRLIDHGGAYTCSCAAETFSELKNAGEPCTHRDKPPAQVHEEFDTMVAGGYEQGEMVLRVRTNIEHKNPALRDWVAFRIVDRPHPRDTAADYRCWPMLDFQSGIDDHLTDVTHIIRGIDLQDSAKRQGFVYDYFDWEYPEVVHWGRVSVDEYEVSLSTSTLSERIQAGDLNGWDDPRAPTVASLRRRGIKGDALVAAMTELGVSASNVNLSMSSVYSANRELIDDAANRLFFVRGEPAEFPVRGGPDAGAPPVHPDYDSRGRRTLPVNDGVAVEQADCPAEGERVWLKGYGPVRRANGVFEYTDDDLSVTNNGVDIVHWVPAETSVSLRLRTIKGDVTGLAEPRVTRVTPEEHRSVRAGWVRTGRQHHAAGRVLRTPMIGSAVVRTGRNSSGSVYLRRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4P2</accession>
    <name>U1P4P2_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00632</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88487">
        <property type="protein sequence ID" value="ERG88487"/>
        <property type="gene ID" value="J07HX5_00632"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1598956_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="166" mass="17296" checksum="9DADC062A67983F2" modified="2013-11-13" version="1">MLEPKCLHRGNSTVSASVETSRPGCDPHPSRSALILSTHEIGTPGKGDTVTISESNDTSVALIVDAGVSVTVNTSHPGTTADEPAELDTSVEVWGHDDEYAVVDLLAEDDDANVYASASADGIEQWGIEIGSVDIPMTKPHVSPTIVDDTLYAGGGENNMHALSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4V8</accession>
    <name>U1P4V8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00708</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88562">
        <property type="protein sequence ID" value="ERG88562"/>
        <property type="gene ID" value="J07HX5_00708"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2204028_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11187" checksum="D34CFA5D1A229699" modified="2013-11-13" version="1">MFWGSVGLSVAYIPVLYAGCGQSQLLAIGAALGDAVYLAVGHGHIPGRSPITDYRLAVTNRHSGLTDKPRPMGVTVVPPSSGSKIGKKDIVDIHQYLQAEQAECLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P597</accession>
    <name>U1P597_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Archaeal Zn-finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00863</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88717">
        <property type="protein sequence ID" value="ERG88717"/>
        <property type="gene ID" value="J07HX5_00863"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110112_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012041">
        <property type="entry name" value="Znf_CPxCG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42195">
        <property type="entry name" value="PTHR42195"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19769">
        <property type="entry name" value="CPxCG_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015877">
        <property type="entry name" value="UCP015877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="218" mass="23706" checksum="4FE1DA7B2C7DC658" modified="2013-11-13" version="1">MTETTETTKQVGLSCPACSPDRPVGHEVLRAGGQATVRCTACAHVHKQSLPDQRTLERRVVISQNDESITTTVEIPAEEQLAVGEEFLAETDQAVLTARITSLELADGRQDQAQADAVRTVWSRAVGNVVVNVTIHPNSGASEATRSLELRVPGDYEFVVGEADDLGGESFTVEGIHVRDDATGYEFDKVDHDGDTVLAKDIKRLYVRDQSTTAWSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5C9</accession>
    <name>U1P5C9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00893</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88747">
        <property type="protein sequence ID" value="ERG88747"/>
        <property type="gene ID" value="J07HX5_00893"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012366_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="4">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="3">
        <location>
            <begin position="161"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="585" mass="62990" checksum="3CFCC179E512CD82" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5Z5</accession>
    <name>U1P5Z5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acVLRF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01112</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88962">
        <property type="protein sequence ID" value="ERG88962"/>
        <property type="gene ID" value="J07HX5_01112"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051790_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040783">
        <property type="entry name" value="VLRF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18859">
        <property type="entry name" value="acVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acVLRF1" evidence="2">
        <location>
            <begin position="185"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="305" mass="34151" checksum="03B8F8D082054AB1" modified="2013-11-13" version="1">MLDDLLGRTALQERITELEETLKQREDERDRLEQQLEAERERRSDAVTERQAAQRRVNKLEDRITQLEDRLDRLQSETTELSVRRETTLRGDRLAAVLDRLESFKTGPEGALTAAVADGHDLPAAVGETLGDRTGLVSRAAPCIVVADDASLVSACLRPPVQPAPFVEWGPRFRLDREWFQPHGRYTLAVVRSDLFAMGTYQADDRTAFHGFDEDITTQHSKGGFSQARFERLRDEQIDSHLDRCRAALAERAADRLYLVGEGSVLGALADLEPAVTTTVDATGAPEVALEAAFDAFWRVQLRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P631</accession>
    <name>U1P631_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable beta-carotene 15,15'-dioxygenase</fullName>
            <ecNumber evidence="1">1.13.11.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01157</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>all-trans-beta-carotene + O2 = 2 all-trans-retinal</text>
            <dbReference type="Rhea" id="RHEA:32887"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17579"/>
            <dbReference type="ChEBI" id="CHEBI:17898"/>
            <dbReference type="EC" id="1.13.11.63"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Brp/Blh beta-carotene diooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.63" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89007">
        <property type="protein sequence ID" value="ERG89007"/>
        <property type="gene ID" value="J07HX5_01157"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068196_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02093">
        <property type="entry name" value="Beta_carotene_diox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022270">
        <property type="entry name" value="Blh_monoox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15461">
        <property type="entry name" value="BCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03753">
        <property type="entry name" value="blh_monoox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="345" mass="36675" checksum="91209D7A8E3A23E2" modified="2013-11-13" version="1">MSTPATAAPGRDTRETTLLWVITAGWLVLGMTAVGATVTGTLPRAYQYVPLLVSVAVLGLPHGAVDHLLIPRWREERPSLQWFGVIAGVYLVVGSLYAVVWFLVPVLAVGVFILVTWYHWGAGELYPLREFAGVDYLGGRTAQVLTVLVRGGAPMLIPLVAFPTEYQFVADSLVGLFDAGAADALTPVFSRSARIAVGVVYTGCAVGALGLGYVRTETPAAWRVDAIEVTVLIGFFLLVPPILAIGVYFCFWHSLRHVARTVLLHGPSAAAVERGEIVSAAQQFGRDAAPLTAASVALLGGLYALVPADPTELSGLVGLYLVLIAVLTLPHVVVVSWLDREQGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6V8</accession>
    <name>U1P6V8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L40e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl40e</name>
        <name evidence="5" type="ORF">J07HX5_01465</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89307">
        <property type="protein sequence ID" value="ERG89307"/>
        <property type="gene ID" value="J07HX5_01465"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_205640_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00788">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="L40e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_L40e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023657">
        <property type="entry name" value="Ribosomal_L40e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39649">
        <property type="entry name" value="PTHR39649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L40e" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="5609" checksum="3C1AE80CEE7E5907" modified="2013-11-13" version="1">MANFDAAQEKIFTTQICMRCNARNAQRADRCRKCGYGNLRPKARESRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P750</accession>
    <name>U1P750_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PQQ_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00092</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87951">
        <property type="protein sequence ID" value="ERG87951"/>
        <property type="gene ID" value="J07HX5_00092"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_878512_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PQQ_3" evidence="1">
        <location>
            <begin position="274"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="33057" checksum="228C5D58EF6C34E1" modified="2013-11-13" version="1" fragment="single">LVGAACFPPLAANGTVYIGVKPSNYYCTVSAFDVDSGRQQGTLSTSQTLSLSAPAVADETVYLGDRDAVHALNSTLGQVLWVTKLGSYTRTSPVVTDDSVYVGCDDGVYALQANHADRLFTTQAAVTSLCVADGTVYLGDEDWTVYAVDASSGTQQWSREISGAPRSVVVENGSIYTGTFAGLGPGTPGLHAIDADTGRLRWHKEHPTTSASVVDDTVVTCGDGVCGFDVESGATRWQFTDIQETQPPISVSDGTAYFGEVLTGQLYGLNVSSGAVSWTSEIDEPTITSVSVGDGIGFVGTADHSLYAVELDGHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P767</accession>
    <name>U1P767_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00112</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87971">
        <property type="protein sequence ID" value="ERG87971"/>
        <property type="gene ID" value="J07HX5_00112"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="30"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="374" mass="39264" checksum="1769856B7A46BB4E" modified="2013-11-13" version="1">MRAKGKHAKHTLVLVPTHSVMRAAVLQDYGEPLAITDVEKPTPAPDGAVVSVEACGVCRSDWHGWQGDLEWIGAQPETGQIMGHEPAGTVVETGEEVTTIKEGDHVAIPFNLADGTCPECLRGHSNTCANTLPLGFAEQAQGAFSEEVHAPNADFNLARLPENVSSVDMAGLGCRFMTSFHALAHRADVSPGDWLAVHGCGGVGLSAVHIANALGANVVAVDLSDEKLEMAKSLGATATVNASQTENPGQAVQAETGNGADVSVDALGIADTCQNSILSLGTRGQHVQIGLTTQDDAGTVSLPTDMMVTREIEFIGSSGMPPNRYDEIFRMMRTGKLNPSGIVSETIDLSTVNNKLEAMTNFETQGIPVIDSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P778</accession>
    <name>U1P778_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exodeoxyribonuclease VII, large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00122</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87981">
        <property type="protein sequence ID" value="ERG87981"/>
        <property type="gene ID" value="J07HX5_00122"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023625_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_anti_2" evidence="7">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="6">
        <location>
            <begin position="105"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG87981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="414" mass="45534" checksum="F6CC84878440EE68" modified="2013-11-13" version="1">MNAEGVHHDYIVGDITSPSASSSDHLYFTVEGDSCQLQCVVFSFRRDGLSDEPNDEMRALLRGDLEYYADRGQMSLRVTDCHEIGEGSYSQVYQQTKSQLESEGLFDDEHKQPMPQLPQTIGLVTSKHGDAVDDAIESIHSRHPGIDIEVAHATVQGDNAVESLTPRIANLDQDPSIDLIVVTRGGGADSTLRTFNELPVCRAVARTNTPIAAGIGHETDEALADRVADERIMTPTDAGSLVPDRTVLKDRCDQLTHRVEATCGSLVKSKLAGLSDSHQNGYVQLTKTKLRQLDGDLAQTTKHAMETRLHARSNTLEEAYTSSIETRLATADSQLTAALRRHNETRLYDLNAQLEQAYATFEREREYKTQIEAAKSEAKAEATQEVATRERAYQAALVVLILLLLGVLGVTFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P788</accession>
    <name>U1P788_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lignostilbene-alpha,beta-dioxygenase related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00137</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87996">
        <property type="protein sequence ID" value="ERG87996"/>
        <property type="gene ID" value="J07HX5_00137"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_898953_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="PTHR10543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="309" mass="33827" checksum="1EC91F76A46B07B2" modified="2013-11-13" version="1">MQSAAGFHSLTDETSSSLAVNGSLPEWLTGSLVRNGPGTFSLSDEESVDHWFDGLAMCYRFTFDPGNQANARTNGAENADDAVHYRNRFLETDAYAEAQAGEFDGGFATGESTLRERLAGLFAEPYDNTNIIVERVGDHYLALTESPRAVEVDPNTFAVTGDRQYNGPEPAGQLASAHLKRDPATGTLFNIETEFGRTSQYHIHALTGLNERRHIGSVETDAPAYMHSFALTPRYAILTEFPLRVNPLSFLKPGRQGGFIDQFEWQPDRGTRIVVVDRASGEVVAEPXXXXXXXLPSNSVKSSKSDIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7B4</accession>
    <name>U1P7B4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative archaeal flagellar protein D/E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01606</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89447">
        <property type="protein sequence ID" value="ERG89447"/>
        <property type="gene ID" value="J07HX5_01606"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1870650_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006752">
        <property type="entry name" value="Arch_fla_DE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04659">
        <property type="entry name" value="Arch_fla_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arch_fla_DE" evidence="1">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="136" mass="14648" checksum="6F47555DC3E0C512" modified="2013-11-13" version="1">MIRGQAERPYLETVDVESDMGTVIDWATYLGTNFGAAGALAALRYYERVGWISSTARQTVQTHLSGMSAEELHSKKYDEPGIVSGPLSPLSGTSFGAHAKSLEFIATLSESDLKASMLRIQQAAQQAPVELDRGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7J7</accession>
    <name>U1P7J7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">J07HX5_01697</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89532">
        <property type="protein sequence ID" value="ERG89532"/>
        <property type="gene ID" value="J07HX5_01697"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="15"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="10">
        <location>
            <begin position="228"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="363"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ERG89532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="393" mass="44457" checksum="D6AE0E7900A3088C" modified="2013-11-13" version="1">MSDTEQFDPAGIEAKWQRAWDDAGVFETPDDAVDPTYVLAMFPYPSGEMHMGHVRNYAITDAYARYRRMQGDAVLHPMGWDSFGLPAENAAIERDTNPEEWTSQCIANMKTQMDLMGLGIDWDREVVTYDPEYYQWNQWLFLQAYEEGLVERQGAELNWCSDCETVLADENVTQQPGHEHGICWRCDTPIELRELDQWFFRTTEYAEELYDALDELEGWPDNVRQMQRNWIGKQEGASVGFELTTGDTVDIFTTRLDTIHGATFFALAPGHDVAQALAADNERVAEYIERAAGEELDQSSGVFTGEYAVNPATGEEIPVYVADYVLEEIGTGALYAVPAHDDRDHAFATEHNIEIRQVIEPAPESDTTLQRSTYKQQRTPTMVFSPTAATPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7P3</accession>
    <name>U1P7P3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone, small heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01743</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89577">
        <property type="protein sequence ID" value="ERG89577"/>
        <property type="gene ID" value="J07HX5_01743"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_8_8_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="51"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="161" mass="16842" checksum="CB2EBC29471B261C" modified="2013-11-13" version="1">MSSLCVPCYVLTTAVASVSSVFLSSSNVLTIMTDTSNPLAEVEEIINQLAELNGAPNLPVDLVDTGDELVVLADLPGRDGEELSVSLSDDRTLEIAADKRTSAAGGRRVINELVRGPVERSVTLPAAVEPAKTTASYDGGVLQVTLTKRVGDDNGTEITVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Q7</accession>
    <name>U1P7Q7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01758</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89592">
        <property type="protein sequence ID" value="ERG89592"/>
        <property type="gene ID" value="J07HX5_01758"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2101893_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="39"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="12720" checksum="B68ABFAB01919EAE" modified="2013-11-13" version="1" fragment="single">GTSEGTVRNRVDRLRADGVIERFTVATRTGNVRAMIEVGVDVNVDTDGLTDRLVGWEPVNFVWQVSGDADIVLVVDMADTAALNALITRLRDRTEVVSTETRLILDEWLEPAEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7U3</accession>
    <name>U1P7U3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal peptidase I, archaeal type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00359</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88216">
        <property type="protein sequence ID" value="ERG88216"/>
        <property type="gene ID" value="J07HX5_00359"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037192_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027245">
        <property type="entry name" value="Sec11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="PTHR10806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="PTHR10806:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="5">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="379" mass="40387" checksum="7D5A786B556BF954" modified="2013-11-13" version="1">MRRTIRLGANVFVAVIVAVAALAVLWAVLGLPMGLVYVETESMSPTLEAGDGVILIPTAVTGSPEPGDVIVFDAQELNGGGPTTHRIVEETERGYITQGDNNNAPDQVTDEPPVAQAQIAGQALEIGGRVVTIPYTGTIAATIGGVVDDARQRVNVLLWRLTDTSGLSATQFSYVLTGVLLVLYGIESFREGSGSRRIDRRHVRAGGRGEAPVSAHAILLLLTAVLVVATAAAMVVPGGAQQYDVVASESESPVLVPPGEETTITHGIANSPVLPMTVFVEGAEGVRVDRHEVGLDRGGTANVSATFDVPDSIGHHRFYVVERRYIAVFPESVTRALYTQHPWLPVLGIDALVAVPYYLVGRRFLPARPSRRGQPRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7W1</accession>
    <name>U1P7W1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoesterase</fullName>
            <ecNumber evidence="1">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01823</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89652">
        <property type="protein sequence ID" value="ERG89652"/>
        <property type="gene ID" value="J07HX5_01823"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="165" mass="17702" checksum="700865E39E784803" modified="2013-11-13" version="1">MNIAIISDTHVPSRERQIPAAFRERVRAAEHVLHAGDFDSTSAFADQQELAETLTAVRGNTDPGLGLSRVQTVICGDIEFVLTHGTGPVSGYKRRIARTVSEHADQAPERAVGVGGHTHEPMDMRYDGIRLLNPGTATGAAPGEAATMMTGTVVNGELTIQRHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7X7</accession>
    <name>U1P7X7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01838</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89667">
        <property type="protein sequence ID" value="ERG89667"/>
        <property type="gene ID" value="J07HX5_01838"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1598989_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="6">
        <location>
            <begin position="36"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="174" mass="20123" checksum="9C88DC55AA075121" modified="2013-11-13" version="1" fragment="single">MVKHRDIPDTETIKEVTLKKEPTSEWFACVTVDGKETPEEPDNPDRCVGTDVGILKYAHDSDGRAVGSLDLSQERDRLHREQRKLSRKQHGSNNWEQQRKKVAECHQTIKRKRRDFLHKLSNYYASEYDLVAVEDLDVKPMLESSGNSRNTASAAWDTFTTLLEYKCELEATHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P869</accession>
    <name>U1P869_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00475</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88331">
        <property type="protein sequence ID" value="ERG88331"/>
        <property type="gene ID" value="J07HX5_00475"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529172_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="175" mass="18814" checksum="45C4AF5DB18CA65E" modified="2013-11-13" version="1">MGTRSCGQAKCGNPTDGRASFEVHNLGTASLLIRFVGIYGDVPNPTVDIQSDSFDIDSFEQGPSVVGSGRRQESNSQREYLVVGPDEATRLETTYRPFVFSSDKSETACDGSEHTGEIGFVQSPGPLKSSRGTISYAFTYSLSGGPVRVDSDDGSSRGDPRHAVHSIHLDNRHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P883</accession>
    <name>U1P883_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L39e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl39e</name>
        <name evidence="6" type="ORF">J07HX5_01939</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89767">
        <property type="protein sequence ID" value="ERG89767"/>
        <property type="gene ID" value="J07HX5_01939"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181948_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_L39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_L39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_L39e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="SSF48662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="6023" checksum="540217E31CD5CFEF" modified="2013-11-13" version="1">MGKKSKAKKKRLGKLENQNSRVPAWVIIKTDRDVMRNPKRRNWRRSDTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8C6</accession>
    <name>U1P8C6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01979</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89807">
        <property type="protein sequence ID" value="ERG89807"/>
        <property type="gene ID" value="J07HX5_01979"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1901851_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="13676" checksum="C72313FFF893F27E" modified="2013-11-13" version="1">MFPAGRVVSERQLPTAKPVDFRAVPAVIFSGLTREDTIXXXXXXXXLTGILALAGHTVTTVLHAVGGIGALALVAVVANRVRNQQAVLLVVVMIAANVTGVIWTIVGANEIVVLSHVLIGVFASAGAVLLATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8F2</accession>
    <name>U1P8F2_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00536</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88391">
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        <property type="gene ID" value="J07HX5_00536"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072493_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="14"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="293" mass="31869" checksum="AE79B238007C9722" modified="2013-11-13" version="1">MNDRSNHDRAVEMLQQLGLKEYESKSFVALTRLSEATAKKISEDSEVPRTRVYDAVRVLETKGLVQIQHSNPQQFRAVSISEAATTLRSEYDTRVDKLEKALDGLESAEPGDPREITHEVWSLTGNSAITSRAQSLIDDTADELVLVIGRESAFPESTANRLRTAVGRGVDVIIGTPDPSLRETVSTAVPGAEVFRSELEWLDGSPTAGDDTEISRLLLADRAAILVSSAHTAGADRDEQAVLGRGFENGVVTIIRRLMATGLLPGADPGRTVVTALRSTPGDISRSWSEKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8K3</accession>
    <name>U1P8K3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00601</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88456">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="13074" checksum="DD53106A82421B7F" modified="2013-11-13" version="1">MTAVDEWEQLLADAGELTPAAVDRIVTIHGDRGVRAIEAVDERRIKKYNDFIIVVGHKDEYIVENDGCTCKDAEYNLDADDPKQLCWHAVAVRVARAVGAVDRHEMWYSDVREFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8L3</accession>
    <name>U1P8L3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02039</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89867">
        <property type="protein sequence ID" value="ERG89867"/>
        <property type="gene ID" value="J07HX5_02039"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3387406_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="32" mass="3804" checksum="E89D7807A7CD296E" modified="2013-11-13" version="1">MESTNTEETDEGDDSEERSLIDWLVDMLWIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8N2</accession>
    <name>U1P8N2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00636</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88491">
        <property type="protein sequence ID" value="ERG88491"/>
        <property type="gene ID" value="J07HX5_00636"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1559416_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="1">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18952" checksum="069C1CB87180271C" modified="2013-11-13" version="1">MEVVGDPKRDDEQGRLEIQYDEVDDTFRAFQPVTAPDSRQDSSLAEKSAALDMGANNLVACTTTTGQQYLYEGRDLFADFHETTEEIARLQSKLLKNGTVVSGFANCTGTGHVVVTTHRTRLSVISWSECPRSIAGLQLFCPDSQSCFAVTHGEMSIVKTYQGNIFNRDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8N7</accession>
    <name>U1P8N7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ArCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_02064</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89892">
        <property type="protein sequence ID" value="ERG89892"/>
        <property type="gene ID" value="J07HX5_02064"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009673_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019975">
        <property type="entry name" value="aCPSF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033769">
        <property type="entry name" value="KH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17214">
        <property type="entry name" value="KH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03675">
        <property type="entry name" value="arCOG00543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH" evidence="2">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="3">
        <location>
            <begin position="194"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="4">
        <location>
            <begin position="423"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="639" mass="71181" checksum="D6CFD313C31E467B" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9I5</accession>
    <name>U1P9I5_9EURY</name>
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        <submittedName>
            <fullName evidence="5">Mismatch repair ATPase (MutS family)</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">J07HX5_00937</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88791.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0030983">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
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        </location>
    </feature>
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            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="333" mass="36566" checksum="D1E658E872536248" modified="2013-11-13" version="1" fragment="single">DVLASLATHAARNDWTRPELTDDRTLSIEAGRHPVVEQTTEFVPNDLRVDPERRILLVTGPNMSGKSTYMRQAALITVLAQIGSFVPARRARIGVVDGIYTRVGALDELAEGRSTFMVEMEELANILHSASARSLVILDEVGRGTATYDGISIAWAATEYLHNTVRSKTLFATHYHELTTLANHLGAVENVHVAAEETNGEVTFLRTVEPGPTDRSYGIHVAGLAGVPDPVVDRSRTVLDRLREDKAIEAQGSGPNGGEPTQVIFDIGSGQFRQPGKSDRSPEDEGASLADRFEGDPETVLNQLLDIDVAEQSPIELLERIRDWQRELQDRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9K5</accession>
    <name>U1P9K5_9EURY</name>
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        </submittedName>
    </protein>
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    </gene>
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="159" mass="16796" checksum="B92A4E49209CCCC9" modified="2013-11-13" version="1">MSKRTRREWLCLIGAGGVAGLAGCSSSGTEADGIEQWRFETGDGVPLSVFSSPTVVGGTVYIKSRDYNVHALSAADGTEQWTFEGSGVCLSPTVVDGTVYVGIHDGNVYALSAAAGTEQWRFETEDYVASSPAVVDNTVYVGIHNKMYALSNVDGESTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9M5</accession>
    <name>U1P9M5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_00967</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00967"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="36" mass="4080" checksum="A0FF19C1F6C1C8F7" modified="2013-11-13" version="1" fragment="single">MFAVPDREGTTVLDALIHARGTYDSSLTFWYSCRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9P5</accession>
    <name>U1P9P5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00982</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="161" mass="16502" checksum="EB7200AAAB43CD58" modified="2013-11-13" version="1">MTDNSKQETDSSSESEGWVPVEDRTDDSPAEPAQPFGSITGNDEESAVSDSTTGDDDGLYPLAPGRGSTSGDAPTPVGGEEGTDPLGSETDVPRYARVLGDIGIYLGVAAVVLTVGGLLLAVGGVQPYASVALTFSLLIVFVAMLLGIVFQAHVTDISLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9Y6</accession>
    <name>U1P9Y6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase/DNA polymerase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01052</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88906">
        <property type="protein sequence ID" value="ERG88906"/>
        <property type="gene ID" value="J07HX5_01052"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893101_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="1">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6664" checksum="B9E246FFD26C67DA" modified="2013-11-13" version="1">MARRGRLPGAPTRSQIVCHVDVDCFYAACERLREPALRGEPVVVGMGYEAGETAGSRGDSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA40</accession>
    <name>U1PA40_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01121</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CetZ family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88971">
        <property type="protein sequence ID" value="ERG88971"/>
        <property type="gene ID" value="J07HX5_01121"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058152_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01946">
        <property type="entry name" value="CetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032907">
        <property type="entry name" value="CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="2"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="443" mass="47888" checksum="AB6FE299AB109546" modified="2013-11-13" version="1" fragment="single">MQVGAIGIGQAGGKILDTFLAYDEEIAESPIRSALAVNTAETDLLGLTHVGDDQKLLIGEDTQNGGGVGADNETGASVTTDNIERIHDSLEQMPRHELDGFLILTSLGGGTGSGGTPVIARHINSMYDSLPVYVVGVLPSKREGQLYAYNAARSLQTLLQGASPNNPSHSPDPDSERSGRTAKESSDTRLIGPDESITEAQETASTPLVDNIILIDNDAYSRPDESLEQAWKYINRTIAQAVTDLFAAGEPLENKRIPESVVDTADIKQTLNGGRLSTIGYATSHLETDTTQTLLDRVRGTDSTDLNNHDFDQQEAELRIMNLVREATQTALGFDTTLESVTTGLVLVAGPTDVLNRRGIQRSRDWIQDQIEAPAVRGGDYPRDQPEVQTALLLSGVHESDRLRELYAQAARARQTIEDIDDTEAADTALTDPPTPPDYEHHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAT5</accession>
    <name>U1PAT5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01365</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89211">
        <property type="protein sequence ID" value="ERG89211"/>
        <property type="gene ID" value="J07HX5_01365"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802370_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="66" mass="7336" checksum="BB29DB7799D81710" modified="2013-11-13" version="1">MTEAARLRDSTQILVHPRVIAGLRDDLEEKFIVSVRQEDPHVRIIGSPTEIKAVSEFLARNGIAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAW9</accession>
    <name>U1PAW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylglycerophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01396</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89241">
        <property type="protein sequence ID" value="ERG89241"/>
        <property type="gene ID" value="J07HX5_01396"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1010498_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="275" mass="28953" checksum="B167D7A3CA1B3CF1" modified="2013-11-13" version="1">MATVYSYWLSLEGAWTRGAITGVTLGALVIFVATAVVGVTHSPAVGGRFLTVTGTVLVGLGVLVGRVSRYRRSQPDPQPITLATWVTIGRGAIVVAVAGLVAAGGLSATGHVGWLPGLLFGVAGVLDRLDGWVARTRNAETSLGRRLDVETDGVLVLVGATAVVVDGLAPVWVLCVGLARYLYLLARWVRGDGLAVGYEPRRRLNRLLYVLVLGAVWAALLPVTTAALTRPLLSAVAVPFMLNFFRSWLAXXXXXXXSSPRGQAPRHSACSAGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB71</accession>
    <name>U1PB71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01484</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89326">
        <property type="protein sequence ID" value="ERG89326"/>
        <property type="gene ID" value="J07HX5_01484"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1520879_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="176" mass="18087" checksum="CDD80D0FB59B0263" modified="2013-11-13" version="1" fragment="single">SIADRLTYVMQVDDFLCWADSVHSVAQSYPNTVLLLILGISVVAAGAGLAITAGTSALDSSAIGSSGGLCEYAETSEQSTLVDQTIQVGANSTGEIRFTVPNEEVAVRVNTDALTIATPEIVIEGPNGGTFLQSPVDTVSERDIGVLGSGTYTLKVINEGMGSADIDTTVRAGLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBF8</accession>
    <name>U1PBF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01564</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89406">
        <property type="protein sequence ID" value="ERG89406"/>
        <property type="gene ID" value="J07HX5_01564"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2502935_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9590" checksum="5FDFBC8552217CFF" modified="2013-11-13" version="1" fragment="single">MLSEDRLEQTYPDYDDQIRHTVRVPPEQAETVSPATVLRPALAERVETDLFTHQATGLERLANGDNIVATTSTSSGKTWIYALQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBK1</accession>
    <name>U1PBK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01610</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89451">
        <property type="protein sequence ID" value="ERG89451"/>
        <property type="gene ID" value="J07HX5_01610"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017073_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="622"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="813"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="578"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="847" mass="92997" checksum="750D4D615477A4F3" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBV8</accession>
    <name>U1PBV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01732</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89566">
        <property type="protein sequence ID" value="ERG89566"/>
        <property type="gene ID" value="J07HX5_01732"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1492938_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_III" evidence="2">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="116"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="180" mass="19462" checksum="0255A5BE95C62336" modified="2013-11-13" version="1">MVSAVNASQRLVDVAEAAGADLRLTQIGSTYITSEIRDLRRKNTSVPVAGEGNGGIIFPTYRVARDGAYTAGRLCALLAKRGRPLSELIAPYNDYYNVRYNVAYDAAAERTALIETIDAVADDADGTVDRTDGCRIDHENGWVLARPSGTEPVVRVYAEARDPERADELAATMTEPLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBZ4</accession>
    <name>U1PBZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01774</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89606">
        <property type="protein sequence ID" value="ERG89606"/>
        <property type="gene ID" value="J07HX5_01774"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2019909_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13685" checksum="69ED6256AB8FD873" modified="2013-11-13" version="1" fragment="single">LGTGALLLFPVFVAAVPVYITNRLAAPMVARYREYVADHAAGELVGSHAAVAGALTTLDREYSTQYTQDLRVGWSTRAFGIVPPPWEERKVLDGAIRFFYRRILGTHPPTESRIERLRSRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBZ9</accession>
    <name>U1PBZ9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCA-adding enzyme</fullName>
            <ecNumber evidence="9">2.7.7.72</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCA tRNA nucleotidyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA CCA-pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA adenylyl-/cytidylyl- transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-NT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cca</name>
        <name evidence="12" type="ORF">J07HX5_01780</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14433"/>
            <dbReference type="Rhea" id="RHEA-COMP:10465"/>
            <dbReference type="Rhea" id="RHEA-COMP:10468"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:83071"/>
            <dbReference type="EC" id="2.7.7.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">A single active site specifically recognizes both ATP and CTP and is responsible for their addition.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="9"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89611">
        <property type="protein sequence ID" value="ERG89611"/>
        <property type="gene ID" value="J07HX5_01780"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044679_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01264">
        <property type="entry name" value="CCA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008229">
        <property type="entry name" value="CCA-adding_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042090">
        <property type="entry name" value="CCA_tRNA_nucleotrans_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015329">
        <property type="entry name" value="tRNA_NucTransf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39643">
        <property type="entry name" value="PTHR39643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09249">
        <property type="entry name" value="tRNA_NucTransf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005335">
        <property type="entry name" value="CCA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="SSF55003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03671">
        <property type="entry name" value="cca_archaeal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0692">RNA repair</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="10">
        <location>
            <begin position="38"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_NucTransf2" evidence="11">
        <location>
            <begin position="156"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="462" mass="50363" checksum="4070217FB75DFE74" modified="2013-11-13" version="1">MDRPAFEAVTEGVRDRIVPDPAERDRLEAAVETLTSRAEQAVTKLPVGARIVQAGSTARDTWLSGDRDIDIFVCFPPELDDGTLEEHGIAVGYAVLPDGREEYAEHPYVSGEYDGFDVDLVPCFDVASATDIRSSVDRTPFHTAYVRGQINTELANQVRLCKQFALATGVYGSDLRTRGFSGYLTELLVVEHGGFRPLIAAAADWDPPVRLDPAEHGQTTFGDPLVVVDPTDPERNVAAVLSTENLARFQHAARALAADPRPRLFESVAPDPVDATTVRAAFERRGTTPTAVRVTVPALVDDQLWPQLERSRSGVAGLLGRHGFEVFRDAVLAEDHVPGCDDRTAVLLFELAVAKRPAVERHEGPPVAAQPHADRFYDTYSDTDAAGPFVVGDRYAVERAREHADAASLLDAKLLEASHGAQVRRALAKEYDLLVGDEVGVLADRFGTELAVYLDPTVRQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCF6</accession>
    <name>U1PCF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PilTVapc superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01948</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89776">
        <property type="protein sequence ID" value="ERG89776"/>
        <property type="gene ID" value="J07HX5_01948"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107892_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041120">
        <property type="entry name" value="PIN_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18477">
        <property type="entry name" value="PIN_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_9" evidence="1">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PIN_9" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="143" mass="15054" checksum="100FC67B7A69B209" modified="2013-11-13" version="1">MTVVLDTNALMMPVECDIRLFEELDRLLGESREQVVPQSVVTELADLATGAGKTATAASVAADLARRRCTAHETDAVYADDAVVELATAAVAAPATECEPTGSASGAMSCAVTNDRPLRERLLDRGVPVISLRGENKLTVTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCG6</accession>
    <name>U1PCG6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01958</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89786">
        <property type="protein sequence ID" value="ERG89786"/>
        <property type="gene ID" value="J07HX5_01958"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="54"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="321" mass="34040" checksum="22127EE2ED1E0656" modified="2013-11-13" version="1" fragment="single">MRTGTPRREAVMDPEAVDSVGRVPHGGDDDPSVVDFSANTNPMTPDGVNSVYRSALSDARRYPGAPEAFRQAAAAFVDCDPAAVVPTAGGLAGIRLAVATTVTAGTSALIPTPSFGEYAREVRLQGGEPVFCSHDQLLATDPADHALVVVCNPNNPTGTAYDNAALRSFAARCRDAGTVLVVDEAFLGFTDRPSLAGTAGVVVARSLTKLFGLPGLRMGYLVARGKLGDRLATARRAWNLGVPARTVGTYCLAQTAFVRETRRRVKDERERLRAALTEQLQFEVHSSAGPFLLFETATPDRLLAAAEAAGLKLRDARTFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCY5</accession>
    <name>U1PCY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02129</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89956">
        <property type="protein sequence ID" value="ERG89956"/>
        <property type="gene ID" value="J07HX5_02129"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108521_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11375">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012962">
        <property type="entry name" value="Pept_M54_archaemetzincn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012091">
        <property type="entry name" value="Pept_M54_archaemetzncn_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15910">
        <property type="entry name" value="PTHR15910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07998">
        <property type="entry name" value="Peptidase_M54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005785">
        <property type="entry name" value="Zn-prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="172" mass="19058" checksum="58CC5E03695E81AA" modified="2013-11-13" version="1" fragment="single">MHVDVVPVGEVDPVVKREASSGLRAIYDCEVSVSNPRTVPKGAYDDSRDQHRAEEFIDLAKRVGDGTKNIAITPNDLYYHRRNYVFGLAYLGGSGSVISTYRLRTSSDGGFSDRSAGEIFADRVRKEVIHEIGHTFGLEHCDNNRCVMNFSPTVREVDVKGESLCGSCQRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFN6</accession>
    <name>U1MFN6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00095</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87954">
        <property type="protein sequence ID" value="ERG87954"/>
        <property type="gene ID" value="J07HX5_00095"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079668_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025494">
        <property type="entry name" value="DUF4385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14328">
        <property type="entry name" value="DUF4385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="19602" checksum="A5B0E7AFB1D86C2B" modified="2013-11-13" version="1">MTNPVRGDVSELTDGPEYDLNFRRHPEQYRHTSDERGVFKIEPYKSELLPKWGVATLVEAEAGADAIHEQYREYRRQGDFVGMDMARKYLQMGWTRAMRYAKYPGGQKYEHDDGERVEREPQEWYDEEKREIALVYEQAVDTVREDEAYEQAKQRHRERYRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFX1</accession>
    <name>U1MFX1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00216</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88074">
        <property type="protein sequence ID" value="ERG88074"/>
        <property type="gene ID" value="J07HX5_00216"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040510_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="339" mass="35381" checksum="92B9318F74FE8854" modified="2013-11-13" version="1">MPSPRSNPLNKLVVPDKTHVEEHDLVTDGDVIVGSQSTVEFGVRGQNIIAGEQVEFGGHIEAGGDCRLDMWCTVADDVLAGEDAYVGERVQVGGELRVAGNLDIGDEVEIAEGFDANGWIVIRNPMPTIVYLFVYLSHLLRAGDDGVAEQLAATFVAESVAPMIVPQNARLGDDTWEVSTPAQIGDDCRLHGNIRAAALTVGRDNEIFGSLRAAEGVTVGAGTRVTGNVTTRDGTVRVGPGAVVRGDIAGEHVEVHTDATIEGIIRANKKTSVISKPVTDATPVSETPTAGDTGEVGGEIKTETAAGTEAEAESKTEADKSGPEPAIRPLRSTGDASQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFY5</accession>
    <name>U1MFY5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00231</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88089">
        <property type="protein sequence ID" value="ERG88089"/>
        <property type="gene ID" value="J07HX5_00231"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="83"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="115"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="472" mass="50769" checksum="B74DE6D80B21736B" modified="2013-11-13" version="1">MAVGSIRGANTLLRTAVTAISRRFRLPTSEISSALPAKGDASPVLCTAPATGCHLYYGVTPTMTDAESEPLLTVRDLEKHYPVRSGLLRRVTGHVQAVDGVSFDVREGETVGLVGESGCGKSTTATTLVRLEKPTGGEVRFDGVPVSELDSDTFRRRVQMVFQDPTTAFDPRMTIGASVAEPLRIHGLHDDHARDVAEDTLERVGMAAADADSYPDAFSGGEKQRIALARALTLNPDLLVLDEPVSALDASVQAEILALINELQSAYDLSVLFISHNLSAVRQVCDRVAVMYLGEIVEVAPTEMLFESPQHPYTEALLSSIPRPEPDADLPTGLDGDVPAPEDPPSGCSFHPRCPRVIPPEGEGADLSLKTTRGLVTLRRDLTARAVDGIEPGDVRSAYDLPDELPDENAERTLASAVQAITDDDFETALDRLATVESVCERSDPTVQSVGDSRRTACHHHDSKHGTDWPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGF5</accession>
    <name>U1MGF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zn-dependent alcohol dehydrogenase, class III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00437</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88294">
        <property type="protein sequence ID" value="ERG88294"/>
        <property type="gene ID" value="J07HX5_00437"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_14_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="28"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="198"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="300" mass="31468" checksum="4E52B6014A583A5D" modified="2013-11-13" version="1">MQIEAAVTNEESGPFNIETVELDDPQDNELVVRVVGAGVCHTDMTVRDQLYPTPLPAVLGHEGSGIVEQVGDAVTTVEPGDRVVLTFDYDDDCPSCRDGHPAYCEGFFEHNFGGHRPEDGTSPLSRDGEEISGRFFGQSSFATHAIATERNVVQVGDEVPLELLGPLGCGIQTGAGTVINTLDPQAGSSIAIFGAGSVGLSALLAADLKGCSEIVSVDLEENRLAKAAELGATTTINPTDVDDVVEAVTQATGGVDYAAETTGVPDVAEQAVETLGKRGPSRLLVRQRWGHEQATTSMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGL6</accession>
    <name>U1MGL6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="3">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00493</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88349">
        <property type="protein sequence ID" value="ERG88349"/>
        <property type="gene ID" value="J07HX5_00493"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_3_3_2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HGTP_anticodon" evidence="8">
        <location>
            <begin position="426"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="511" mass="54584" checksum="DD3FEEFE769344CA" modified="2013-11-13" version="1">MNSEQELPTDYEIAQSVETQPITDIVASMGLQPAELELFGEHTAKVTHDARERVRRDQAADATVVLVTGMTPTPLGEGKTVTTVGLGQALTELGKDASIALREPSLGPVFGVKGGAAGGGYSQVLPMEDINLHFTGDLHALTAAHNLIAAMLDNHIRQQTEPAVAVNRIEWPRVIDMNDRALRETVVGLGGPVTGIPREDGFILTAASELMAVLCLADSLAALKDRIARIIVAYDQSGDPVTVGDIDAAGAATMLLRDALKPNVVQTVEGTPAFVHGGPFANIAHGTNSLVADDLAARLSEYVVTEAGFGSDLGAEKFMNIVCRHDGIEPDAVTLVASVRALKYHGTEMWPPEIDALQSEDVAAVRAGFVNLDAHVNNLRQFGVPVVVAVNRSRTXXXXXXXALIEQKNDENGIRWPSDVAPFKTSVIPLTDETQITKMAERIEQSVGTDDVLIFDNDVSIGEKFAESDLIGIPEKVILGNTFLGSGKLEVEFRGGSREFYSPDTFLAECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGM5</accession>
    <name>U1MGM5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00498</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88354">
        <property type="protein sequence ID" value="ERG88354"/>
        <property type="gene ID" value="J07HX5_00498"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="270" mass="28693" checksum="52C465CD9D11FE20" modified="2013-11-13" version="1">MPQLDQTADYDNFELTRKNAVVTVRIDSTSPMNGVNSTLAEEFRTIGRQLREDDGVRAVVLTGTDDIYCAGADLSALNGDDSDGARLRQLATSLHEAISHLLRMQPPLVTAVNGTAAGGGFGLAILGDLVVMSDAARLEFAYPRVGLTGDAGSTFLLPRLVGLRQARELVLTDEPIEPDEAVEMGLASEVVPAAELTARHRELAAELAAGPTHAYGATRQLLLASFERSLDDQLAAETDAIAAAAETDDYEHGYAAFFNSESESPAFEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGN2</accession>
    <name>U1MGN2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ORF">J07HX5_00508</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88364">
        <property type="protein sequence ID" value="ERG88364"/>
        <property type="gene ID" value="J07HX5_00508"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_901962_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="115"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="33173" checksum="A1453E3470123A0D" modified="2013-11-13" version="1">MNNTDGNEATPDADAGTDTGDRESDPTPEDTSSEGPNKDVTPADGPAVNTESDPDSDSGSNSDREAETPTPYDQLHSMVPDEVTRPDDLPDDRREQVAAEPATAARLLVGLVTAHEELTEMVDETRERANDLESRLARKQAEFQNYKKRQERQLEKEKARATEALVERIVDVRDDLARALEQDASVDIRDGVATTLEKFDRELERENVEQIRPETGESTDPTRHEVLASVAAALPEGQIADVHRPGYEMAGKVLRPAQVTVSDGSKDAGSAEPNGGTKTPSTGTDTQDNNGDGSADTDPEAEASEPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGZ5</accession>
    <name>U1MGZ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ICC-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00675</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88529">
        <property type="protein sequence ID" value="ERG88529"/>
        <property type="gene ID" value="J07HX5_00675"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075478_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024173">
        <property type="entry name" value="Pesterase_MJ0037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000887">
        <property type="entry name" value="Pesterase_MJ0037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="23"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="250" mass="26659" checksum="B2CB958061FFFC47" modified="2013-11-13" version="1">MHVEPISGAPAAVVGTADDTAERLLVVADYHAGIEAVLRHEGVEIADAADERRARLRGLIADTAPDRLVVLGDLVHAVGDPWTTERAELQALFSALSVPVIIVKGNHDSKIETVLDTVESVTVTEPTGVRVGDVGFVHGHTWPAESVLNATVVCAGHEHPLVQLEDSVGGGRTERAWVRGQIAPAPFREHGLTVGDRQPELVLFPAFNNRSGGTRVNVEAEFLSPFLPAALPDGEAYLLDGTRLGQYQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH48</accession>
    <name>U1MH48_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription factor S</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Transcription elongation factor IIS/RNA polymerase subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00755</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6 8">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88609">
        <property type="protein sequence ID" value="ERG88609"/>
        <property type="gene ID" value="J07HX5_00755"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="DNA-dir_RNA_pol_M/15kDasu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006288">
        <property type="entry name" value="TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="PTHR11239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="TFIIS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01384">
        <property type="entry name" value="TFS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="9">
        <location>
            <begin position="64"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11785" checksum="8873E3C845576A3E" modified="2013-11-13" version="1">MQFCDACGSMMRPGDDRMTCTGCGATADQDKDRAEQFVSTTEQTTDDVIETSAAANFEGKPTADDVTCEDCGHGTAWYTIKQTGAADEPPTRFFKCKDCGNRWREYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHJ7</accession>
    <name>U1MHJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide/nickel transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00940</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88794">
        <property type="protein sequence ID" value="ERG88794"/>
        <property type="gene ID" value="J07HX5_00940"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="171"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="40672" checksum="6E71238FBF737EA9" modified="2013-11-13" version="1">MGESVLSGLLGPVQEALDPSWVNLVPLLELDGGWISFPVIGVVALHDWLWSITLAGFIYYGVVPLYENQRMTRYYWRRFRKNKAAVISGLFLTVIFFIGVVGSRVLSDPSPQSGLDKLPPVGISTPSYVPGPQATQAAGCTNSDSCSGIWEYPLGTDTAGRDLLLSVINGMEVSMMVGLTATALSVVIAASVSLAAVYYGGWVDEIAFRWVDIQLTFPAFFLYLLLVYTFSGSLFILIMVFGFIEWGGGARLMRSEALQRREEPYITASKAAGANPLWTIRQHLLPNISNTVITYASLSIPSIILAEAALSFLGLGDASVISWGQTITEGRGDLSRAWWVSTIPGIFLFLTVLAFNFVGDALRDAIDPRHGGAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHT5</accession>
    <name>U1MHT5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="7">DHNA-octaprenyltransferase</shortName>
            <ecNumber evidence="7">2.5.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">menA</name>
        <name evidence="8" type="ORF">J07HX5_01025</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cell membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88879">
        <property type="protein sequence ID" value="ERG88879"/>
        <property type="gene ID" value="J07HX5_01025"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043611_1_2_2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="32729" checksum="BF59FD9AA9165ECE" modified="2013-11-13" version="1">MVTDEFAAVHAWVIAARPQTLPVGTAPVVVGTGLAAADGVFAPGPAAAALVGALLIQVGTNLVNDYHDAARGVDADSPGFTRVTEAGLLPPDRVRRGAVLAYLTAVIVGAYLVAVGGLPVVAIGLSAIAAGVLYTGGPCPYGYHGLGDLFVFLYFGLVAVSGTYYVQATAPATLSPPVGLPAGTITPAAVLAGAAAGGLATAVLVINNLRDMETDRAAGKQTLAVVLGARWSRVELAGLFGIAYLIPVVLCLGVGRSPAVLAVWLTLPVAADIVRTASASAAPDELNTTLERTGRLFAAYAVVFAAGVVAPEAGTATGRFLPLALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHW9</accession>
    <name>U1MHW9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein affecting phage T7 exclusion by the F plasmid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01071</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88924">
        <property type="protein sequence ID" value="ERG88924"/>
        <property type="gene ID" value="J07HX5_01071"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1535605_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007313">
        <property type="entry name" value="FxsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35335">
        <property type="entry name" value="PTHR35335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04186">
        <property type="entry name" value="FxsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="174" mass="18635" checksum="07D855919CC7B82B" modified="2013-11-13" version="1" fragment="single">VDALFLVVLTRFLAWQLIVALVVLTALVGLLFVRLAGRHTIVRIQRRLRQGEVPTNELIDGGLLLVAAGFLLTPGLVTDGLGFLIVVPVTRYPFRWGLKRWVLTPYFDEKSGGFVTGRVYTGGFPDGNSGTGTSEAGTGDRPGGDPDPGTGTDAGHGPNRGVQDVDYDEVKDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI13</accession>
    <name>U1MI13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01134</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88984">
        <property type="protein sequence ID" value="ERG88984"/>
        <property type="gene ID" value="J07HX5_01134"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1253533_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="24175" checksum="89A916B5A295013C" modified="2013-11-13" version="1">MSTDSYSRLLRTTRTECTCVHSTGCLQGRRPKHIYLAWFSPDLIVCTLAGLPTLTCGLYIDPRASCETCSYCMLATNSRQQTATPAMGNTAVDSNPRGKRPCSPLSISTSTPDVRADCRRTDAGDFPVSSARDQPTGRPPKLRRDSNHRQARFPGTRPGTTPTSTLNLACELTLLPTADRRPRQSDRWLANCWCACQDEQSLWLRSGAAVLSLESSSSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI34</accession>
    <name>U1MI34_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89014">
        <property type="protein sequence ID" value="ERG89014"/>
        <property type="gene ID" value="J07HX5_01164"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101758_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="153" mass="16797" checksum="50E0C97F4E5B39BE" modified="2013-11-13" version="1">METTRHFTATVYTVNNGAVALHEHDRLGLWLPPGGHVERDELPHETARREVREELGLPVELVAPVGDLASETARSIPRPQAFLLEDINVHDDTVGHQHMDFVYYGTVSTREIDPGPDEAPATAWEWFTAAELAAATELPADVVEVGQRAIAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIK6</accession>
    <name>U1MIK6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01399</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89244">
        <property type="protein sequence ID" value="ERG89244"/>
        <property type="gene ID" value="J07HX5_01399"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2893102_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="62" mass="6977" checksum="C42967A797BBA3CE" modified="2013-11-13" version="1">MFAIGLADLLRRGFQLFNTRPDAIVEVILTISLVYFILTFTTNRLLDWLDSRYAVPGGGDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIR3</accession>
    <name>U1MIR3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease J</fullName>
            <shortName evidence="4">RNase J</shortName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnj</name>
        <name evidence="6" type="ORF">J07HX5_01472</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89314">
        <property type="protein sequence ID" value="ERG89314"/>
        <property type="gene ID" value="J07HX5_01472"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01492">
        <property type="entry name" value="RNase_J_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030879">
        <property type="entry name" value="RNase_J_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="15"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="385"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="448" mass="49996" checksum="20091D4892791EB2" modified="2013-11-13" version="1">MEIEIATIGGYEEVGRQMTAVRAGDDVVVFDMGLNLSQVLIHDDVETERMHSLDLIDMGAIPDDRVMSELEGNVQAIVPTHGHLDHIGAISKLAHRYNAPVVATPFTIELVKRQVQSEEKFGFQNDLVKMDDGETMSIGEGLDLEFVNVTHSIIDAINPVLHTPEGSIVYGLDKRMDHSPVIGDPIDMQRFREIGREGEGVLCYIEDCTNAGKQGRTPSESVARRHLQDVMHSIEDYEGGIVATTFSSHIARVKSLVEFADDIGRKPVLLGRSMEKYSGTAEQLDFVEFPEDLGMYGHRKSVDRTFKRIMNEGKENFLPIVTGHQGEPRAMLTRIGRGDTPYDLTEGDKVLFSARIIPEPTNEGQRYRSEQLLGMQGARIYTDIHVSGHMRQEGHYQMLDALEPQHIVPAHQDMSGYSEYVNLAEGKGYSVGRDLHTSRNGDLIQLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ56</accession>
    <name>U1MJ56_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01645</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89484">
        <property type="protein sequence ID" value="ERG89484"/>
        <property type="gene ID" value="J07HX5_01645"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139141_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043739">
        <property type="entry name" value="DUF5684"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18936">
        <property type="entry name" value="DUF5684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="124" mass="13604" checksum="51C4DCAB66029A9B" modified="2013-11-13" version="1">MYVLSLPTAGSVVLSVGLLITFLQVAGFWMVFAKAGEPGWAAIVPIYNIYVLVKISNNEWWWLLVFFIPLIQIVAIVKIQLNVASEFDQGTGFAVGLILLPIVFYPLLGVGDYQYDAGPPSIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJB7</accession>
    <name>U1MJB7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">J07HX5_01730</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89564">
        <property type="protein sequence ID" value="ERG89564"/>
        <property type="gene ID" value="J07HX5_01730"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074878_2_0_2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="73"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="143"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="202" mass="21044" checksum="8C783EB605874D5A" modified="2013-11-13" version="1">MIAFVETASDEADDSCHVGAAGRHTTQLLVGAIMSEVGAFLRETGAVQFGEFQLAHGGTSEYYIDTYMFETEPDALAAVGAAFAEQVETTLAGVALGGVPLAVATSVASDYPYIIVRKQTKDHGTGNRIEGDLADGERVSVVEDVTTTGQSALDAVNALRDAGAVVNKVFVVVDREQGATERLADHGVTLEPLLTATELLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJQ1</accession>
    <name>U1MJQ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01896</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89724">
        <property type="protein sequence ID" value="ERG89724"/>
        <property type="gene ID" value="J07HX5_01896"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048140_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28771" checksum="49D225777518B0F2" modified="2013-11-13" version="1">MRRFTAEYLEQTRRGMWEDSQAALAALRLDEAKTVLDVGAGTGELTRILRENSPGQVLSLDADRSLLSQTETPRLLGDATRLPVADSVVEVVVCQALLVNLPTPAAALDEFVRVAQSRVGAIEPDNSAVTVESTVPAEPALMASARRRYLCGVQTDPTFGDGRELFEHAGLDAITVQRYDHHQSIEPPYSDTAFEAVRRKATGAGLKTRRETMLAGNTTAEQFDQLREAWRAMGRTAVEQMRNQEYCYSETVPFYVTVGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV22</accession>
    <name>U1MV22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00061</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carotenoid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87920">
        <property type="protein sequence ID" value="ERG87920"/>
        <property type="gene ID" value="J07HX5_00061"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="510" mass="56444" checksum="509E6ECF9FD971C9" modified="2013-11-13" version="1">MTNGAGSAIDGEEIGIVGAGFGGLSAAAHLEDAGADVTILEQHEHAGGYAGRIERDGFRIDTGPSWYLMPGVFDRFFESFGRSHEEFYELTELDPMYQLRWKDGDEETVPADRAGQKRLFESYEAGAGERLDDYLADAAEAYELGMDRFVYPSRSRLRDMLDPDILRSARALPKLRTMDSYVGSYFDNPKLRQIAEYKLVFLGGSPYNTPGIYTLMSHVDMNLGVYHPTGGIASVIDAFVEVGTDLGVDLQTNTAVTGIEPRGDQFVVETNGRPQTFDRVVSNAPPPYVEHELLPDTYDRREDYWDSRTYAPSAFLMYFGVEGDVDLDHHTLVLPTDWKPHFDKIFDNPAWPDDPAYYVHVPTKTDPTVAPDDHEIVFVLVPLAPGLDDDTETREQFREQVLDDMAENADVDFRDRIVLEETASISEFSEDFNAPGGTALALAHTLDQTGPLRPSHRAPGLDGLYYAGAYTNPGIGMPMCILSGEHVTEAVLEDARDSMGPSVVPTSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVA7</accession>
    <name>U1MVA7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00019</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87878">
        <property type="protein sequence ID" value="ERG87878"/>
        <property type="gene ID" value="J07HX5_00019"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257252_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="103" mass="11789" checksum="7182778390DB772C" modified="2013-11-13" version="1">MTTFLRTAPTKYVTNEDCEFRQATLHRRDGEWYPHGSIIKIDDTDSTTGHRTVLGVGLGVNQLAVASTGRFWSADEFNHWKRECEKRRGDLQXXXXXXXXRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVP3</accession>
    <name>U1MVP3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00328</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88185">
        <property type="protein sequence ID" value="ERG88185"/>
        <property type="gene ID" value="J07HX5_00328"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="5">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="5">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="432" mass="45027" checksum="F6C2DEBFCABD0035" modified="2013-11-13" version="1" fragment="single">MSVRTANISVSGMSCASCASSIEDAVTKRPGVDAADVNFATGGATVEYDPAKGSLAQIYEAVEAAGYEPERATATVGIAGMSCASCATSTTEAIEAVPGVLGADVNVATDEATVIVNPNDASMAAVYDAVEAAGYEPDRPEANTDTTGPAADRERAVERELRTKRRWVIVGGLLTAPFLLVMAEMLLGASLFLPAWVDWVEFGLATALIGTLGRHFLAGAYTAASNGRANMDTLVAVGTTTGYLYSAAVLASIVTGGLYFEAVAFVLWFIYVGEYLEVRSKARASDALRELLELQAEEATVVEWETDTAKAGTQTPAPGDEQVVPVEAVTVGDVLKVRPGGRIPTDGTVVGGQSGVDESMVTGESVPVDKTPGDEVLGGTINEGGVLYVEATSVGEDTAIRQIVQRVKEAQSRQPDVQRLVDRVSAYFVPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVT4</accession>
    <name>U1MVT4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00225</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88083">
        <property type="protein sequence ID" value="ERG88083"/>
        <property type="gene ID" value="J07HX5_00225"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2839251_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="65" mass="6960" checksum="2838DA9B090009B7" modified="2013-11-13" version="1">MHLSDSAAPRHEEQASGIAGFDSGIKTDADVMQYTDEQQQCVLQTTASSSQWIAADCDALVEVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW57</accession>
    <name>U1MW57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00361</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88218">
        <property type="protein sequence ID" value="ERG88218"/>
        <property type="gene ID" value="J07HX5_00361"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3036625_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="5925" checksum="0E433CFFECF49222" modified="2013-11-13" version="1" fragment="single">MTSVKRVRVETPASAARAGDGRFQFTDAYSVFDWGPMPDTIPRKGASLCTMGADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWF5</accession>
    <name>U1MWF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative exonuclease of the beta-lactamase fold involved in RNA processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00595</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88450">
        <property type="protein sequence ID" value="ERG88450"/>
        <property type="gene ID" value="J07HX5_00595"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009673_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="13"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="223"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="410" mass="44577" checksum="45AC8FB58414973B" modified="2013-11-13" version="1">MNVEFLGGAREVGRSAILINDSLLLDYGLDPATPPQYPVGDADPDGVVVSHGHLDHAGAVPALLTGDARPPVHWTPPTRELALTLAEDTLKLHGSTPQCPFTETHVRRLTQVSETHSYGEPFTVAGHEVTLFNAGHIPGSAHVVVDDGDQRLLYTADFHTDDQRLVAGSRARPDVDVVLTESTYANVEHSDRERLEDRFAESVRTTVWEGGTVVVPVFAIGRTQELLMVCEAHDINCYVDGLGTQVTRQLRRHPEFLNNPDGLQRAKSSARIVSGADGQRRRIADQNTVILTTAGMLTGGPAVTYVGEIYKRPVNKIALTGYQVQGTPGRELVDTGSAELDNQMLPVSAQVEQYDFSAHADREGLRSFLAAYQDTPILVNHGDDCVGFADRLREDGYDAQAPALGDRVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWK1</accession>
    <name>U1MWK1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00492</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88348">
        <property type="protein sequence ID" value="ERG88348"/>
        <property type="gene ID" value="J07HX5_00492"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1691486_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="16577" checksum="8C9C592D8620FFE9" modified="2013-11-13" version="1">MATDGNPDRTDTDNPLGPPEGPVAHAQVTMEFADDSAAAVVDAFEHYAEGGAVPCDFRTFVTNYALETVEIVFNHTDADDLRDRINAVEANQAGPVPTAPSPGTAEPSAVNRPPTDPAVIVVDGWTHLPAEIAVEQWSHGRDATISTGRYKRIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWT8</accession>
    <name>U1MWT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC-type uncharacterized transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00761</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88615">
        <property type="protein sequence ID" value="ERG88615"/>
        <property type="gene ID" value="J07HX5_00761"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065735_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="312" mass="32163" checksum="FEC2CCE9A74911D7" modified="2013-11-13" version="1">MNNRQSTVIVSVLAISLIAVAGIAGVTIAATEVSVDLAGGDGGGGEGTAFTPAENITTPQYDADTVVSNDTPGTATVTMSSAASGSTVVIDTSTFTNNYAIQPLAQTLAENGYDIRVLTGTDSVETDLDNATGLLTLGVTEYSEAEREAISDFADAGGHVVVTVEPSAAFSSADQSELFASIDATPQPGYVYNLQENDLNYQRIFAAPSGSPTLTAGVDRVVFDTATTLSAQSAVETLRPIDGSQRSVTRAATTAPVVTRSDGFVTVGDTDFLSPANVQRADNDAFVGNLAEFLVEGEEYSGQSQSARSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWV3</accession>
    <name>U1MWV3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00776</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88630">
        <property type="protein sequence ID" value="ERG88630"/>
        <property type="gene ID" value="J07HX5_00776"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1880986_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043927">
        <property type="entry name" value="DUF5778"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19090">
        <property type="entry name" value="DUF5778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="16009" checksum="45F9D8958519BEC7" modified="2013-11-13" version="1">MDERAQQDLERRAWQLLQPGAIDLHGLVVRTEFDGQQEPAMHQATVEIGDQIARHAGYDPTETFVYSGTDDPEFASNQHQGRRLDDESFVWECQQLLRNGSFDIVFYFDATADTETLLAAVEAASYDATGLDGTASSPAAAVIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWX8</accession>
    <name>U1MWX8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00628</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88483">
        <property type="protein sequence ID" value="ERG88483"/>
        <property type="gene ID" value="J07HX5_00628"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2645727_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="76" mass="8522" checksum="63C2ACF514B1D7CB" modified="2013-11-13" version="1">MRSKLRGLAEQRPHNRAHLCRLAVFDGVEQRVDLRLLADALAGLFIHYQLLQIDSKNTAGLPSGVASNRLKYARPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX11</accession>
    <name>U1MX11_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00831</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88685">
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        <property type="gene ID" value="J07HX5_00831"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
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        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
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        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="PTHR22855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="2">
        <location>
            <begin position="70"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="3">
        <location>
            <begin position="334"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="581" mass="62792" checksum="63EA9EB46F2E05C7" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX17</accession>
    <name>U1MX17_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00836</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88690">
        <property type="protein sequence ID" value="ERG88690"/>
        <property type="gene ID" value="J07HX5_00836"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126924_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="204" mass="22865" checksum="081A823C0F0A6D7F" modified="2013-11-13" version="1">MRPVGETLLIRTDAYLILDRLYKLMNVRNWNDLLTEVVESDVDPSGWRAVGGDRANGIGEDLFIGHREAGAYQLKTYAKNPYQVDGVGTQIARKVDEDIEPLFPTEADGLFGVQQPIPEEEAPERASDLEAVLETHADAPTTPDALFEDVMDALDSPAYGPMEFDSHDRPDRLDELTATFEEAQQVLETEFEEVVDETVDRGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX66</accession>
    <name>U1MX66_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation initiation factor eIF-5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00724</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-5A family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88578">
        <property type="protein sequence ID" value="ERG88578"/>
        <property type="gene ID" value="J07HX5_00724"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102600_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="PTHR11673"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0385">Hypusine</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="13942" checksum="EA41B564EF22BA96" modified="2013-11-13" version="1">MARQQSEVRDLDEGSYVMIDDIPCTINSYSTAKPGKHGSAKARVEARGVFDGRKRSLSQPVDAKIWVPIITRKQGQVINVDGDEVQVMDLETYDNFVMKAGDENMNVDEEIEFLEYESQRKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX68</accession>
    <name>U1MX68_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH:ubiquinone oxidoreductase subunit 1 (Chain H)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00886</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88740">
        <property type="protein sequence ID" value="ERG88740"/>
        <property type="gene ID" value="J07HX5_00886"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="347" mass="35526" checksum="0662FF526C2E64D8" modified="2013-11-13" version="1">MTTTTLPDRIAGALGLSGPGGAIVGAIAGATVVAVFVLANAAVAGPWAKRKITAAFTDRVAVTHIGPAGLLIIVADSVRLISKELIVPAGVDRPAWDLAPVVLAGAGLVGFAVIPMGSGLHLADPAVGLMLAFAASSVASVGLVMAGYASNNKYSLLGSLRAVAQTLAYEVPLVLTGVSVAIFAGSLQPSVIVDAQTQSLTAGPITAPAWFAVVNPVAFVIFLVANMAEVGRNPFDITEAPSELVAGYQTEYSSVYFVLVYLGEFVHIFLGGAIAATVFLGGPAGPVLPGVVWFVAKIWAVFLLTQWTRSALPRIRIDQLVAVSWKLLVLLALANLVLTAALVGVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXK8</accession>
    <name>U1MXK8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00889</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88743">
        <property type="protein sequence ID" value="ERG88743"/>
        <property type="gene ID" value="J07HX5_00889"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092679_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="36"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="205" mass="22331" checksum="ADB757C21020C4BA" modified="2013-11-13" version="1">MASYGRSSLRDLFDDAPTPHIAHPPHTHHRDFYLATDGSFRDTGGGLGAVIQTRDGQRVTRVSVPHQAPDNNVAEYRALHLGLDVLSNRSPAEARVGLLVDHDQLAANVNAAVLAAHDTRATPHQISVPHDTGLHWRGIRARLREFGAVRAARIPSDRNPAHPLANAPEEYRHLDAGSERCLRPAPVDDGQPIPPPSRADRTVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXS4</accession>
    <name>U1MXS4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00954</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88808">
        <property type="protein sequence ID" value="ERG88808"/>
        <property type="gene ID" value="J07HX5_00954"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1656822_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="159" mass="17251" checksum="DBA867CADF2CD3DB" modified="2013-11-13" version="1">MKSRRQFLIGVTTAGTIAIAGCSGGGGGGGPEGAAEQYITASKNGDAEAINEVLHPESDRYPRSEENVKEKDSLTIKKVEQVSTRRVVESQLDQFADADPTEQEVEKVTNNLEQNVETRLNETGTDEHNWVLATIEQGGEKNTAPFLTVKDDGDWFVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXU9</accession>
    <name>U1MXU9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylglutamate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00979</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88833">
        <property type="protein sequence ID" value="ERG88833"/>
        <property type="gene ID" value="J07HX5_00979"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053680_2_1_2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="282" mass="28803" checksum="68C8553C33A37722" modified="2013-11-13" version="1">MSRTVVKVGGADAVDQDGTLTAIAALAAAAQEEVVVVHGGSTAVDEMLETLDIDPEYVETPAGVIGRFTDAETMTAFTMVLPGRLNTDAVARLQSEGVDAVGLSGVDGGLLSGPRTGAVRIQSGDQTKIRRGDHSGRIESVNDALLEGLLADGYTPVVSPPMAGADDGVVVPVNTDADRAAAAIAAALEARLVLLTDVQGVLANASDPTTLIETVRTPTDWSRLVDAAEGFMQRKCMAIEEALAGGASRAIVASATEDRPARAALDGGGTHVHPEAVEEAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY35</accession>
    <name>U1MY35_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01069</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88923">
        <property type="protein sequence ID" value="ERG88923"/>
        <property type="gene ID" value="J07HX5_01069"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_8_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="159" mass="17771" checksum="2B7F4B554AA97E6A" modified="2013-11-13" version="1">MTVEVSEAIEIIYIEDNSDIADVTATFLERNDDRFTVETFPRAGVALDWLEQSLPDCILSDYDMPGMDGVEFLKQVREEYSKLPFFLYTGKGNESVASSAISAGVTDYLQKETGLQQYELLANRISNAVTKYRAEQTAANRLHELQQTNKNSAGSSHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYC8</accession>
    <name>U1MYC8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gas vesicle protein K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01173</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May play a structural or regulatory role in gas vesicle synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
            <location evidence="2">Gas vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vesicle</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89023">
        <property type="protein sequence ID" value="ERG89023"/>
        <property type="gene ID" value="J07HX5_01173"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155015_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031412">
        <property type="term" value="P:gas vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007805">
        <property type="entry name" value="Gas-vesicle_GvpK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40137">
        <property type="entry name" value="PTHR40137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05121">
        <property type="entry name" value="GvpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11633" checksum="7197C533AD22845E" modified="2013-11-13" version="1">MSTTIDLSDDDGENLRQGLVTLVVALVEIIDDALEKEAVRRMESGELSDEEINRLGAQLKQLDAELERLKEKEGVDQNVAELRGQLDGLLDAALRQLQQTEETNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYD3</accession>
    <name>U1MYD3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01333</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89180">
        <property type="protein sequence ID" value="ERG89180"/>
        <property type="gene ID" value="J07HX5_01333"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="35"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="504" mass="54257" checksum="C158E3D610897086" modified="2013-11-13" version="1">MSKLSVTANPSEQVADDLTIAPITGWNAQYIDGEWIPAGDRETIAVEEPSSGAEIGRIPVGTADDVDTAYQAAARAQSDWETTTAHERAAVINDAREIIRGWEDELIYLFAAESGSVNAKARSELNSLDAIMEVSEGLASQVSGEYRTSPVENKETQVRQKPVGVVGVITPWNFPFHLSMRVVAPALAAGNAVVLKPDEQTPYLGGHVIARAFEEAGLPAGLLNVVTGDGAQTGDAVVTHETPRMISFTGSSEVGRKVGARAVEQFAYPELELGGNNVHIVTENADLDWAVDSGVFGSFTHQGQICISINRHIVHESVYDEYVERLSDRAAALPIGDPHEPDTVVGPIINEQQRDKIVEFIAQSQERGAVVETGGGHDELFVEPTVLSNVNQEMPVACNEHFGPVAPVIPYETESEALAIANDTRYGLSGSVHSTDLSQAKRIATELETGMVHINDQPVNDDPNTPFGGVGASGLGRYNGEAILDRLTETKWISIQNEPRDYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ54</accession>
    <name>U1MZ54_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01624</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89465">
        <property type="protein sequence ID" value="ERG89465"/>
        <property type="gene ID" value="J07HX5_01624"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1953237_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14099" checksum="2BF383C84ADA2614" modified="2013-11-13" version="1" fragment="single">RMTTAVETAEANTERRVPDGHDQSVLVLDTEAYTHRYEFPPDRLLLDELFRRQGDEAAAVVGVGRDEAHIRTAAEIDLRSVVETAGDQATSAALDARAIREGRVEFLAGEREAVQRALVEALADALER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZA4</accession>
    <name>U1MZA4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01516</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89358">
        <property type="protein sequence ID" value="ERG89358"/>
        <property type="gene ID" value="J07HX5_01516"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_582079_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="51"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="184"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="264"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="391"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="470" mass="51627" checksum="7FDB9A71E9275B9A" modified="2013-11-13" version="1" fragment="single">MIEASAVICPLDAVRDSPNRRGAGLVDRYVRGNLISYRHMIPVMSMSTPPAEICVLSVTGGGGAVGDTLEDRFDRFTVATATSAAEGLDWLQAGAFDCVLSEYEMARTDGIGFLQAVRKIDTELPFILHTDSGSEKIASEAISAGVTDYVQTEGQDPPESEHWDRLADRITHAVSTQQTAADRSQQRLEQTLKTVPACIVQLGPDGEFTFANERATEVLGIDRSELIGRTYNGPNWAITDTAGNPIPDEELPFQQVRETGEPIEDVRHTITLPDGTEKVISVNGAPLEDDTGALRSVLFAITDITGRYERQQTLERQNDVSKKAQAVADVGAWEYDVAADSLHWSEQVYEIHDIDQGADVQLADAIEFYHPEDRVTIQEALTAVIEAGEPYETEARLITAEGAERWVRTSADPQTENGSVARLRGTIQDITASKTREQQLQRQRDRYQSLFETPADHLGEDFSAAAEYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZV0</accession>
    <name>U1MZV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01912</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89740">
        <property type="protein sequence ID" value="ERG89740"/>
        <property type="gene ID" value="J07HX5_01912"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3128454_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5310" checksum="C41031F43C041F7D" modified="2013-11-13" version="1" fragment="single">MSFSALGRHPVNTETDACIVCPGPTLRPLGHSPTEPVVAEPWSPEQVVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZW5</accession>
    <name>U1MZW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01771</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89603">
        <property type="protein sequence ID" value="ERG89603"/>
        <property type="gene ID" value="J07HX5_01771"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1691505_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="131" mass="13577" checksum="7528DFDC17E8F50B" modified="2013-11-13" version="1" fragment="single">MDVTGDEIAGVAGLFNGATREELAAALAELAYKRGESHDPAAFHDPVDRAIERYHIVAVETDHDTAAAESVLVPGPVAFPAPPTGADDLPHILDVPDRAVDRTAAGEAAAERLLAEAATAVDAGDTDRITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZX0</accession>
    <name>U1MZX0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Replication factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01777</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89608">
        <property type="protein sequence ID" value="ERG89608"/>
        <property type="gene ID" value="J07HX5_01777"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043913_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="3">
        <location>
            <begin position="75"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="3">
        <location>
            <begin position="176"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="REPA_OB_2" evidence="4">
        <location>
            <begin position="275"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="507" mass="53534" checksum="B2A02620B48C32E9" modified="2013-11-13" version="1">MGAIEEIYEELEADVSEQRFQEAVEQKVAQMEGLADQETAAMIIAHELADGEVGAISEIEPAMDEVKFLAQVTGVGDVRTFERDDDEQEGQVVNVEVADETGRVSLAFWDRQAEAVVAGEIEVSDVLRVKGRPKDGYDGLEVSVSEAEIDADAEIDIDADDGDATVESLSLGQSDVRLQGQVLDTGTVRSFDRDDGSTGQVSDLVLGDETGRIGVTLWDEMASRAEALSSGITVEIIDGYVRERDGELEVHVGERGAVETTDATVEYAPETTPVAAVELGATADIAGVVRSTDPVRTFDRDDGSEGQVRNVRLQDDSDDIRVALWGEKADKEIAPGDEILATDVEIQDGWQDDLEASAGWGSAVVVLDGAAETASADVEATSETDQPADGTAAATTADAGGADETGLSAFVDGQPADATAEQDSSTSQSAASDSHAQTQTQSHAQAQTQTQTEAEFTGTVVQTGDPVILDDGTETVTVETDARVRLGEELTVRGAFQDGRLDAEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZY1</accession>
    <name>U1MZY1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01788</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89618">
        <property type="protein sequence ID" value="ERG89618"/>
        <property type="gene ID" value="J07HX5_01788"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_736937_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="375" mass="40859" checksum="02DD2AF84B923769" modified="2013-11-13" version="1">MQSRRRRRLLRATAVGTLGAAAGCLGGVFDGGDGETGEGDDQPESETGQDTDDGQQSGEAADEETTTESQSVDPASLGDAPFYQWLLTPLEEGPIADYSFRYFDFDQLAAVSDLFPRFGSNEGDSSVVPGGGTDTARLDLGPGAVTQSSDYSGQQIGFPITVMTGEYDTDAVVQAIESEDKWDRQAASEQTTLFVAERTESTPRRTWAINPSTFLDVRHLLEEQDTTVAERLLETRAGRAPRVYEQSEELRRLLELVDGETXXXXXXXSVWGPHRPAGVGRTRRRCERTAGRRGPVVSGVTKPDRSNRTNQCNFSSTRCSVDSGATSGCVHTTRRTHSKQVLKLRLTCSRLRTQKTDASSRAISPSAHGLRTRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZZ4</accession>
    <name>U1MZZ4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Type 2 DNA topoisomerase 6 subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Type II DNA topoisomerase VI subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">top6A</name>
        <name evidence="10" type="ORF">J07HX5_01803</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Relaxes both positive and negative superturns and exhibits a strong decatenase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Heterotetramer of two Top6A and two Top6B chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TOP6A family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89633">
        <property type="protein sequence ID" value="ERG89633"/>
        <property type="gene ID" value="J07HX5_01803"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037229_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00132">
        <property type="entry name" value="Top6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004085">
        <property type="entry name" value="TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="PTHR10848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01552">
        <property type="entry name" value="TPISMRASE6A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="SSF56726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TP6A_N" evidence="9">
        <location>
            <begin position="74"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="41797" checksum="E54E5A6EA92AA28A" modified="2013-11-13" version="1">MSKPDQPQTTDDTQQRLLALAEQFYDQFAAGDVPRMQLPTRTKSNIEYDEEDNVWVYGDRTSTRTAKTIGGAQKLLKAAYAVEFLETQLEQDRSSTLRELYYLSESWDLDEAQFSSQDESNQLIEDLEIALETTREEFHMRPEESGATVMGPLELREQTRRGERVIHCQKDVGEGGYQIPNNPDTIEFLDHDAEFVLAVETGGMRDRLVENGFDDAYNTIVVHLKGQPARATRRLTKRLQDDLGLPVVVFTDGDPWSYRIYGSVAYGSIKSAHLSAYLATPEAQFVGVRPQDIVEYDLPTDPLSDSDVNALESELEDPRFQTEFWEDQIELQLEIEKKSEQQSLASRGLDFVTETYLPERLSEMGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N032</accession>
    <name>U1N032_9EURY</name>
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        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01845</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89673.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89673">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="165" mass="18275" checksum="EE41C2E596EEBEF2" modified="2013-11-13" version="1">MTEIHATQRVAVLADSQNLYHSAQTMYTQNIDYAAMLEETVAGRELTRAIAYVIRADSTDEESFFEALVDIGFETRIKPIQTFADGSKKANWDVGMSLDAVTLANHVDTIVLCTGDGDFVRLARHLHHEGVRVEVVCFGGSTAERLVEAADQFTDMSADTDRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N035</accession>
    <name>U1N035_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01987</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89815">
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        <property type="gene ID" value="J07HX5_01987"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_210071_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="51" mass="5884" checksum="7F518EE57BBDF177" modified="2013-11-13" version="1" fragment="single">MPYCQNCGSFVTTDYARVFTPNDTEKPRVCPQCEDKIRDGADVRKARSTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0A9</accession>
    <name>U1N0A9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01930</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89758">
        <property type="protein sequence ID" value="ERG89758"/>
        <property type="gene ID" value="J07HX5_01930"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2985535_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="16"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6173" checksum="29D33554A9DD3CD5" modified="2013-11-13" version="1">MLESSGNSRNTASAAWNMFTTMLEYKCKREGTHFVEVDPAGTTKKCASCGVATDKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0B5</accession>
    <name>U1N0B5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytoene/squalene synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01935</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="120" mass="13841" checksum="5F62F649B4F98E67" modified="2013-11-13" version="1" fragment="single">RREEPSEGFRRAVQFELRRAEQRYRKGVAGIEYLADGGQFAVVLAAVLYAEHHRLIRNQDFDVLSTRPELSRSRKLWLVARTWWNWRRFRDPVTVFRRVSAVPAGTGVGGGAEHGIPQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0H1</accession>
    <name>U1N0H1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01990</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89818">
        <property type="protein sequence ID" value="ERG89818"/>
        <property type="gene ID" value="J07HX5_01990"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1691488_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="16538" checksum="CFBA4AECA33D1CF2" modified="2013-11-13" version="1">MSSWVMSVPLSADRAQQLRAAKTSVLVPYGVWFDTHLKMVPAGSGVVCVAGRGRQLTPLMWGGSWLRQLRTAGGCHCTGAVVVIRSESRSSLLTSGAFCGRSETAAARPHLGDGRWPRSPNRRRAEKCRTLGARCSRGRGTVVVAVHAGGERNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0J6</accession>
    <name>U1N0J6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02015</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89843">
        <property type="protein sequence ID" value="ERG89843"/>
        <property type="gene ID" value="J07HX5_02015"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3112921_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="50" mass="5244" checksum="E3060A36E4FA7D22" modified="2013-11-13" version="1">MALRYFACTDCATVVARPDPPSVCGCCGATTLEELSLRPSAAAYFGSELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0K8</accession>
    <name>U1N0K8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02020</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89848">
        <property type="protein sequence ID" value="ERG89848"/>
        <property type="gene ID" value="J07HX5_02020"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1032430_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="269" mass="28641" checksum="ACA1567EACE62A78" modified="2013-11-13" version="1" fragment="single">KKWAFDTDDWVDSSPTVSNGVVYFAVANGKFYALDADTGETQWVNDHGGGYASPTVVDGTVYTQRGGSVYAFDAGTGNQHWSYSIGSNAMSSGVQTDAYFSADPSPAVKSGLVFAGLDTLSDRGVYALSKYTGEKIWKCSQKIYSSPTVVDGTIYAGIQDGVCAIKTFNGNKKWTFDINGRVTSSPTVAGSSICVGGPDEETYVIDSEGSKKQEYGCSSPIESSPTVFRDYALHRTNGGALLGWNVSDYAGTQSDGTRVKQRVLGHHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3C7</accession>
    <name>U1P3C7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00143</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88002">
        <property type="protein sequence ID" value="ERG88002"/>
        <property type="gene ID" value="J07HX5_00143"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_881681_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="7">
        <location>
            <begin position="87"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="7">
        <location>
            <begin position="174"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="315" mass="33367" checksum="75B2DF1AD2A35EF5" modified="2013-11-13" version="1">MTVAGVVSWLAYTAIQTDTPPAGTDRQALPRYTRRGRTRWTCVHRLSTANQHGTLNSCSSLRSLVSQHAVSAAQEILAIVAGDPFAVMNTVGLIAFALVGSSKAIREEFDLLGITTVGLAMAFAGGVTRDLLVVREPLALQSPAEITLGFIGVGLAIALQGVLRSPDDHPVTLIADAIGLAAFTTTGAIVATAADVSAFGIVAIATINAVGGGALADVLLDRPPFILFEDFYASCAVVGGTAYLSXXXXXXXXKQCRSQPRCGLFDKSSARLCNQSSDHSLNAVPIDLIVRCADRVPVCCRLARRCSYWSRLWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P459</accession>
    <name>U1P459_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00435</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88292">
        <property type="protein sequence ID" value="ERG88292"/>
        <property type="gene ID" value="J07HX5_00435"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1987531_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="13524" checksum="59D9ED52223D9017" modified="2013-11-13" version="1">MLPGERDELVVLLPVVNVGSGVVERGCHLGPPRHSVRAGGLLAYLLPLVKSLEPVVDSLLADVGGRRLGDGLMKLCGRENGRVSTVKRQQDILISDLLAERPPSPRGWLLIAARAYRCQPKPFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P498</accession>
    <name>U1P498_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="4">DERA</shortName>
            <ecNumber evidence="4">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="4">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoC</name>
        <name evidence="5" type="ORF">J07HX5_00471</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88327">
        <property type="protein sequence ID" value="ERG88327"/>
        <property type="gene ID" value="J07HX5_00471"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_0_2_2"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="4">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="22451" checksum="EE5EC576C7103D9B" modified="2013-11-13" version="1">MPLADRIQHTEVAPTADRERLTAFLSECREHGFDGAMVQPCWVPLAAKTLAGTDVSVCTAVGFPLGGGRRHARVAAIRDAVAAGVDEIDVMGNIGYLKSGMDEAFRAGLDAMVAAADDTTIKLMLELGGLTDAEAEREIDHAVAAGFDYLKNSSGFGAGGDATVERIAFIADRVPGSVGIKASGGIATAAQATDLLDAGADLLGASSGVAIVSGERGDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4M6</accession>
    <name>U1P4M6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00612</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88467">
        <property type="protein sequence ID" value="ERG88467"/>
        <property type="gene ID" value="J07HX5_00612"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084184_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="256" mass="26464" checksum="327A512E0A08A2A1" modified="2013-11-13" version="1">MPTNYAKTLIVALAVVVLVMAIGLVGFGPAGADGPTTDTAPLAQADTENESSIEQTIAIDATGTASAAPDQATVRITVSETGNQTDAVRDQLAAGSTALESALDELGVEYRTIRYEIEEPPRHVDRELPPVAGTHVYKVVVEDTTRTGTVVDAGADAGAEVTDLTLTLSDTAREELRNEAVVDAMTDAEEQATALAGTNGLTVGEPVSIDATQGRYSPVEQLSGAFDGGDSETDISTGDVSVTYSVEVVYEAASED</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4U2</accession>
    <name>U1P4U2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00688</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88542">
        <property type="protein sequence ID" value="ERG88542"/>
        <property type="gene ID" value="J07HX5_00688"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025112_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="106"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="7">
        <location>
            <begin position="410"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="178"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="118"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="514" mass="57428" checksum="3C062E695013D8A7" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P516</accession>
    <name>U1P516_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00778</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88632">
        <property type="protein sequence ID" value="ERG88632"/>
        <property type="gene ID" value="J07HX5_00778"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127770_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018714">
        <property type="entry name" value="DUF2237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466">
        <property type="entry name" value="PTHR37466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09996">
        <property type="entry name" value="DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="16308" checksum="2442103B12099D5D" modified="2013-11-13" version="1">MPGAFLTGDRSPVADRSHSKKYARTLQIYVTDELNVLGTELVPCGTDPATGYLRDGCCHHLPSDPGRHELCAAVTDEFLEYSRRQGNDLITPRPAVDFPGLEAGDRWCLCVGRWTSAREAGVAPPVVLEATHEAVLSDISAATLREHAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P548</accession>
    <name>U1P548_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Superfamily II helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00818</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88672">
        <property type="protein sequence ID" value="ERG88672"/>
        <property type="gene ID" value="J07HX5_00818"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_675452_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC63" evidence="1">
        <location>
            <begin position="109"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="401" mass="42662" checksum="40E41B042A520EC7" modified="2013-11-13" version="1" fragment="single">GYAHVICDADDASRYRRLLADGKAIESRLAISDDPPGELAVHLNAEIALGTIGELDDIVDWLETTFYYVRAQRTNVPDGQLRRRLRSTLTWLTEHGFVERAGSELALEPTSLGRLASEFYLRLETARRFATVATDHVTEPAVLRAVAAAAEFDSANARADETDAIQAVLGDDATELAPGARKVLAVVRAQMAAATPSELKSDAWVIRQNALRLLAAFRAIVDQLGTAADANLVRRLEARVETGVGDDAVGLTAIEGVGAQRAETLAAAGYRSPAEVATATAETLAAAGITDTVAARLQNNATELPAIEVAWGAFPTRIGRGERTLREVQVRSTAGSARAGLTVTVNNVEMTAKSSYLGETTLPVGVFGSDTDALTIAVRVVFPELPLEPIVHSKTVRVEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5A2</accession>
    <name>U1P5A2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00868</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88722">
        <property type="protein sequence ID" value="ERG88722"/>
        <property type="gene ID" value="J07HX5_00868"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109670_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH bat-type" evidence="4">
        <location>
            <begin position="160"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23424" checksum="2DAD061E2A90371C" modified="2013-11-13" version="1">MTSAEPDKQPHKQMSTHTSGPLHARLAVTPPAETDCPVVSHCSQGAAVGHSIKQRGDTETRDQECHAELICDDGVGTDQQYHQSAVVSECPCPMFEAHDCIPDLRGVRNGALIYVVSVPSRTVLRKLVAAVRENGAAVTVEWLVTSAGESSLTEIDVSAITAKQRRALEAAIEAGYYETPRTASLGDVADRLSVSTSAVSQRLNAAETTLVKSLFGADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5E5</accession>
    <name>U1P5E5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00908</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <begin position="92"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="157" mass="18071" checksum="9DF2C0033F24F2EE" modified="2013-11-13" version="1">MLTPAACEREIRSLHQFFQAWYHGELPRDRFDRFADALAPSFSRITPEGTVQTRGTVLAGVREEYDRQATKITVQAVQMIDHSNQRALVRYEEQQTPGTDRLSTVLFGPRPDHGESENKGKSERPQPEEPSHKKTEKTTPPPKQERPVWLYLQETSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1P602</accession>
    <name>U1P602_9EURY</name>
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        <recommendedName>
            <fullName evidence="1 13">DNA ligase</fullName>
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        </alternativeName>
    </protein>
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        <name evidence="13" type="primary">lig</name>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="13">DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.</text>
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            <name>Mg(2+)</name>
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        </cofactor>
    </comment>
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        <text evidence="13 14">Belongs to the ATP-dependent DNA ligase family.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
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    <keyword evidence="2 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="15">
        <location>
            <begin position="357"/>
            <end position="494"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <position position="269"/>
        </location>
        <ligand>
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        <location>
            <position position="276"/>
        </location>
        <ligand>
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        <ligand>
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        <location>
            <position position="321"/>
        </location>
        <ligand>
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        <location>
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        </location>
        <ligand>
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        </ligand>
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        <ligand>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88972.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="595" mass="64906" checksum="256BAA79338BDEC9" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6E5</accession>
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        <submittedName>
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                <person name="Narasingarao P."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </location>
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        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6N1</accession>
    <name>U1P6N1_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Exoribonuclease R</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_01387</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
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</entry>
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    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88201">
        <property type="protein sequence ID" value="ERG88201"/>
        <property type="gene ID" value="J07HX5_00344"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_15_12_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="6">
        <location>
            <begin position="16"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="30766" checksum="AAD584F233453971" modified="2013-11-13" version="1" fragment="single">MADDNLSRSLGLYPTLMISIGAMIGSGIFVLPAIGFVEAGPSVIIAYLLAAVVVLPAALSKAELGTAMPESGGDYLYIERALGPLAGTIAGIGAWFSLVFKSAFALVGLGAYLSLITPFSTTQVTLVGVGLAVLIVTLNIVGTELTGQAQALVVSVVLVGLVAYVGNTAWLASTDGVTADPSRLSGLTETAPGTVVTAAALVFVSYAGVTKIASVAEEVKDPDANLPRGILGSLGIMAVVYVGVIGSIVVLNAPGVLAAEDGAHEASLTPMADGADALFAGYGTIIVSLLAVIALMSMANAGVLSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7W3</accession>
    <name>U1P7W3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zn-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00379</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88236">
        <property type="protein sequence ID" value="ERG88236"/>
        <property type="gene ID" value="J07HX5_00379"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="10"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="352" mass="36310" checksum="774DF7B8C50BED16" modified="2013-11-13" version="1">MDAAILREHGAPLEIRSVPAPAPGPNEAIVAVEACGLCRSDWHAWQGHGEWANDRVSRGQILGHEPAGRVIATGGSVSRITTGQQVVVPFSLGDGSCAHCQTGHGNVCPNGWALGFEADAPGAFAEQVRVPAADYNLVALPSAISPRDAAVLGCRYMTAYHALADRAGLGGGEWLAVHGCGGVGLSAVQLGSALGARVVAVDPDQTARNRAREIGASHALDPAASDPVEAIAEITDGGADVSTDALGIASTCQNSVNCLRTRGTHVQLGLTTDAERGTVALPTDRMTRWELSFVGARGMPPTQYDALFDLIAATEIDPGALVGRELSLAAVSDRLAAMTDYQTAGVEVVTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7X5</accession>
    <name>U1P7X5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Isoleucyl-tRNA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00394</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88251">
        <property type="protein sequence ID" value="ERG88251"/>
        <property type="gene ID" value="J07HX5_00394"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896029_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anticodon_1" evidence="6">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="310" mass="34215" checksum="8077C2CA9010AAD3" modified="2013-11-13" version="1">MSYALHRVVALLAPFTPLVADEIYSRLTGDAGQPTVHMCEYPAPDERWRDEQLETDVALLRAVEEAGSNARQQAERKLRWPVQEVVVAPDDDRTAAAVRRHRGLVADRLNAQTVEVLAPDEQWDQLQYSATADMSELGPAFGGRATEVMTALNAARVQDPSVDALETQLRAEGVLDPNEAVTDAMVSVTTETPDDVSGAVIEIDGDELGVVYVDTGLTEDIKSEGYAREVIRRIQQMRKDLALDIEERIRVQLGVTDDRVATLIDEHEELIAQEVRATVFETVEDGYQKQWEIEGVSVEIGIEPVPEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7Z6</accession>
    <name>U1P7Z6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Preprotein translocase subunit SecG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Protein transport protein Sec61 subunit beta homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">secG</name>
        <name evidence="14" type="ORF">J07HX5_01859</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cell membrane</location>
            <topology evidence="1 12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the SEC61-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89687">
        <property type="protein sequence ID" value="ERG89687"/>
        <property type="gene ID" value="J07HX5_01859"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_208205_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00751">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023531">
        <property type="entry name" value="Preprot_translocase_SecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="6 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="53" mass="5508" checksum="8EB63A58B0818F30" modified="2013-11-13" version="1">MSSQESGSGLMSSAGLVRYFDAEDSKGVSLDPKTVVTLSVLIGVLVIFLNAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P809</accession>
    <name>U1P809_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00424</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88281">
        <property type="protein sequence ID" value="ERG88281"/>
        <property type="gene ID" value="J07HX5_00424"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040882_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="441" mass="48729" checksum="380E2D92C27B5BD2" modified="2013-11-13" version="1">MWAREHGQAAVVLSNRAIWLSWEINNRRQAHICVTQYPYHTVYDDWSPSNQFAWSIPLLLAVVVLIGLAGGSIVIANLVDSGPPDPPSSVEAAERLDDLDTIELVGNRTRQVDGNTSWAVTERAVRIGTGKFRDEIVAAGSERASATAGSLSVSNGSVRYTYIANTDRLFRSEVNESEQSERSENVRNLFAAVGDELDQSVPIFPTFSPSESSNSSTEWRDTAVTVEYRGTETVAGRDNYVLQLEPVTDDVRLVSATLWFDQEYLYPLQYNRVIDRPEGRYNYTFTPQTITFNPSLEDSLFEFDAERLSADPAVFNTERFDSYAEMAAALDRPTPKLSLSEEFDFVGGSRFDGPTQSLSYRYADGVGEDATVVRVFVTDQSAEYPGNETITIGGQQVTRSTSGGDTEFSWQRGDWNIVVSGTADQSTLRSIVGTTLTDGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P880</accession>
    <name>U1P880_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00485</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88341">
        <property type="protein sequence ID" value="ERG88341"/>
        <property type="gene ID" value="J07HX5_00485"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013181_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="330"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG88341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="386" mass="41331" checksum="0B0A35682F6CD44D" modified="2013-11-13" version="1">MDLSTGSELDRIRAANVAHSPVPVGTVPLYEAVKRAGDPTAITHEQLLDIIEKHATQGVDYMTLHAGVLMQHLPLTNDRKTGVVSRGGSIIARWMEETGMQNPLYTEFTEICRLCAKHDVTVSLGDGLRPGCLADASDPAQFAELKTLGELTERAQKYGVQVIVEGPGHAPLDDVADTVERQQAICDGAPFYLLGPLVTDVAPGYDHITSAIGAATAARAGAAMLCYVTPKEHLGLPEQADVRDGLAAYRIAAHAADVANDQPGARDWDDAVSEARYEFDWHQQFELALDPARAQAYHDETLPGDNYKDARFCSMCGSAFCSMRIDQDTRTDDTELSSPDGETDLASSSAAETNLPPVGTHDTAAVPKPTETDSISSDAASPQDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8A4</accession>
    <name>U1P8A4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01959</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89787">
        <property type="protein sequence ID" value="ERG89787"/>
        <property type="gene ID" value="J07HX5_01959"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087823_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002808">
        <property type="entry name" value="AdoCbi_amidolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01955">
        <property type="entry name" value="CbiZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="214" mass="21916" checksum="962ECA3F13981BA0" modified="2013-11-13" version="1" fragment="single">TRWLSTGWNGGTEHAATAYNVSVPEGWPEVDLGAYVADRRARAGFDRAGPTLFTGVGLEHLRGARCGPVEAYATAGLSNPGALPVPAADGGVRPESRGRFGTVNLLVGTRRALADGALANLVAVVAEAKATTLLAEAGVPGTTTDAIVVGSDPDGETAVFTGSATQVGEATRACVREALLASLRSRYPEGAYPDTVAAAEYGCATDRQAEVFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8C9</accession>
    <name>U1P8C9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type antimicrobial peptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00510</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88366">
        <property type="protein sequence ID" value="ERG88366"/>
        <property type="gene ID" value="J07HX5_00510"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="248" mass="26858" checksum="BC4839D0E190B2C6" modified="2013-11-13" version="1">MSISPESDTDTETRLSPDTEPVVDLRDVRKEYELGGTVTALDGVDLALADGSYSAVMGPSGSGKSTLLNLIGALDTPTDGDVVVDDEDVGTLSESGRARLRGTEIGFIFQTFNLMPRLTAVENVSLPLMFAEWDQERRRERAETLLADVGLGDRLDHMPQELSGGQRQRVAIARALSADPALILADEPTGNVDTETGEEIMSLLRDANNRGNTVLLVTHERRIAERADEIVHVTDGIIEGIESVETEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8J4</accession>
    <name>U1P8J4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00591</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88446">
        <property type="protein sequence ID" value="ERG88446"/>
        <property type="gene ID" value="J07HX5_00591"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075224_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="53" mass="5922" checksum="005AB7948E7BA18D" modified="2013-11-13" version="1">MPATEELRCTSDSCELDMFENHYTYEVDDDLTVSDLNCPLCGGSNCLEQITLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8P2</accession>
    <name>U1P8P2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00652</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88506">
        <property type="protein sequence ID" value="ERG88506"/>
        <property type="gene ID" value="J07HX5_00652"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_16_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="168"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="396" mass="43588" checksum="EB9966A2F8408E7C" modified="2013-11-13" version="1">MRVGLVVYDGLDGTSGGFLYDRRVVQGLRDRGHAVTTVAVPRRSYTRNLLDSVSQSVWRQLTALADNVDIILEDELCHPSLVGPNLRLRRRESSPPIVSIVHHLRSSEDWSPLRTRVYRTVERAYLLTADAFVYNSHTTRETVESLIGPTTGVLAPPGRDHLQPAVTREQIRARAHNEGPVELLFVGSIVERKGLETLLKGLAALELPWSLTIVGDTTIDRAYTEQLQSLVKQLAVGDRVTMTGRVPQSRLNELYEQCQILTVPSQYEGYGIVYLEAMGHGLPAVGTRAGGASEVINDGTTGALITPGDVSALTNAVARLAADRDRLAAHALAARAAFDDHHTWDETAGAVATFLRRQRHPHPHRYRHRRPVRNSDGDSNSVCLFNPASLSVCDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8R0</accession>
    <name>U1P8R0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00672</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88526">
        <property type="protein sequence ID" value="ERG88526"/>
        <property type="gene ID" value="J07HX5_00672"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="1"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="454" mass="48186" checksum="767185E134655059" modified="2013-11-13" version="1">MESINPATGEPIETYERDDTAAVEQALDQAATTFAAWRDQPLATREAVLAAAAAELRDNVEEYAALMTAEMGKPITQARSEVEKCAWVCDHYAENAGAYLHDDRHPSPPGVDARTSYEPLGPVLAVMPWNYPFWQVFRFAAPALAAGNVGLLSHAPEVPGVARAIERVFDRAGAPAGAFQTLLIGVDPIHETILPDDRVAAATVTGSNPAGRAVAATAGDQLKPTVLELGGSDPFVVLDDADVAAAAEAAAQARFQNTGQSCIAAKRLLVHEAIFDRFRATFLEAVDELTMGTPTADETDLGPLVSKRHRDGLHEQVTASIEAGATLVRGGTLPDRPGAFYPPTVVADIPAGCPVDAEETFGPVATVYQVPDADAAIAKANETQYGLGASVWTTDRDRGRAVAERIEAGNVFVNELVKSDPRVPFGGIKKSGYGRELAAAGIHEFLNRKTVWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P938</accession>
    <name>U1P938_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00797</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88651">
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        <property type="gene ID" value="J07HX5_00797"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171539_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="84" mass="9228" checksum="DD8AE4692D92B96A" modified="2013-11-13" version="1">MCANRVEALESRIKELEASVEGLTDELVECKLRINELEEAIGEDRSFGSSDTDTTTQFEAEAPTDDAEDTNKSTTDDNDDIIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>U1P960</accession>
    <name>U1P960_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone acetyltransferase, ELP3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_00817</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88671">
        <property type="protein sequence ID" value="ERG88671"/>
        <property type="gene ID" value="J07HX5_00817"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025983_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="PTHR11135:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
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    <sequence length="494" mass="56071" checksum="FC44C61F5ED47D99" modified="2013-11-13" version="1" fragment="single">MSQRPTTESSQAGDADAFRRVCQELIDRILSGEVTRENLEAAKREVCGKHSAPSVPKNSELLDFAGENRDRVEPVLRRKPVRTASGVSPVAIMTSPHRCPHGKCLYCPGGPDSEFSSAQSYTGKEPAAARGQQNDYDPYGQVTLRLEQLRKIGHPVDKVELILMGGTMTARSHDYQEWFVKRALQAMNEYDPSGIPEPAEGVSFAQDPTEREFRYVEDVIERNETTDVRNIATTFETKPDWCDPEQIDRMLRLGATKVEVGVQSTYERINREMHRGHGIQASIDATQRLRDAGFKVGYHMMPGQPGMSKAMCLEDFRRLFDRPEFRPDYLKIYPTLIVEDTAVYDWHHRGEFEPLSSVEAAELVAEIMELIPRYTRLQRVQRDIPAGLIEAGVQKSNLRQLADKRTDDACECIRCREVGHADDQPETIERDIMEYDAAGGREQFISFEDFDRDVLIGFCRLRFPNEPSRAELNDAALVRELHVYGDQVEVGQET</sequence>
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    <accession>U1P991</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="EMBL" id="ERG88706.1"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
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    </evidence>
    <sequence length="78" mass="7916" checksum="C9BA0E35BBFBC8AC" modified="2013-11-13" version="1">MASVKKAVISRVETGASAGQGSDTTRKMTAAGYKRPASDKSETTVFVAGTIQSSGVCPMSRPATGGRSSVSETAVCRC</sequence>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="784" mass="85224" checksum="F78D178799177644" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9L8</accession>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
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    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="37476" checksum="5BBFAC871657BB63" modified="2013-11-13" version="1">MRIVVRTVAWSAALLAAVIAVVVFSTTLGPASIGPATVLKATLNGVAIPTSVAVSGATVTPFGVLSVPVPAVDIGWSQPFSFAVAEKDAIIVRLVRLPRILLGAVVGFALATAGTVMQGFFKNPMADPSIIGVSSGAAVGAVLTIAFPLALPFGLQAAAFIGALGAAAVVYLIATENGRTPVATLLLAGVAIQTFLGAVISYLLLQADEGLREAVVWLMGHLNRASWDDVVITAPLAALFFLLLLAYARDMNALLLGEEDAASLGIAVERTKRLLLAGSSIITAAAVAVTGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGAAFLVLADTVARVGPAEVPVGIVTAAVGAPFFLLLLARREVHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAA0</accession>
    <name>U1PAA0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Imidazolonepropionase related amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01182</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89031">
        <property type="protein sequence ID" value="ERG89031"/>
        <property type="gene ID" value="J07HX5_01182"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023620_2_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="53"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="403" mass="42700" checksum="1E54D9D7F550610B" modified="2013-11-13" version="1">MQYIHCGRLLTGDTAPIDEAGLLVEDGYVAAAGPHEEIDVPAEATHIDHSDATVTPGLIDAHLHLQGVRSMDPFSWVRESSELGAARATADLRALLAAGFTAVRDVGSQTGLGLKTAVEDDTVPGPRVFTSGRSISQTGGHGDAHYLPYEWADDRGISTLADGPAECRKVARKRIRDGVDCLKIMTTGGVLSEKDAPSQSQFTDAEIQAFTEEAHRVGLPVASHAQGAAGVKAALENGVDTIEHGFHLDDEALELFETTDATFVPTLAIMYRLVTQGDDHGVPEYGLKKAHTAREAHFESTRRAYEADVPIALGTDFLGPALVPHGENALEAELLVEEIGLSEREAIEAGTRVAAQTVPASDIGVLEPGAQADVLAFETDPLADIRALREPDAVYKGGEPVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAN3</accession>
    <name>U1PAN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01314</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89161">
        <property type="protein sequence ID" value="ERG89161"/>
        <property type="gene ID" value="J07HX5_01314"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="25"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="257" mass="27685" checksum="8D8E8647F51B75D8" modified="2013-11-13" version="1">MEIVSHDERATAYTSVEADTEQKQLLYVHGSGGTHAAWSLQYQRRRGRVPVAGLDLSGHGHSEDLSATDQTALAAYAADVAAVARRVDADVLVGHSLGGAVVLHLLLKGGYDPAGVVLASTGAKLAVAEPLRAALATEFETAIEWLHKPDRLFHDPNREAVEQSKAAMRDIGQPVTRRDFRTAHSFDVREQLEAIDVPTLAVGGVHDSLTPPRYHEYLAAELPACEHVSIAEAAHLAMLEQPAAFHAAVNTFLERLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAV0</accession>
    <name>U1PAV0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane exosortase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01381</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89226">
        <property type="protein sequence ID" value="ERG89226"/>
        <property type="gene ID" value="J07HX5_01381"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965469_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13671" checksum="F317049D09201123" modified="2013-11-13" version="1">MVSAALEAASELVAPLGWLVLGGFLLGVGLETVGRRELARPTLVAAWLGFAGFWALLVYPWLVFDQSVIRAVGAAAAAPLSILIARLLYRKDRDLFVLSRAIAFMGLLYAPVIAIXXXXXXXRWAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAW3</accession>
    <name>U1PAW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01391</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89236">
        <property type="protein sequence ID" value="ERG89236"/>
        <property type="gene ID" value="J07HX5_01391"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490323_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="86" mass="9492" checksum="7F0CA5DD2903AA19" modified="2013-11-13" version="1">MMPQAQLVQHNVLQQCENKNQGWVRAATTTGTGFGQWKLTPRLWRRSLLAARLXXXXXXXXQRCETNLGGGSRLPLPSALVSINGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBF3</accession>
    <name>U1PBF3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01554</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89396">
        <property type="protein sequence ID" value="ERG89396"/>
        <property type="gene ID" value="J07HX5_01554"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2079335_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="117" mass="12673" checksum="42B9A66F4267B2CA" modified="2013-11-13" version="1">MSSWFSRTDIGNFQPCATPSRVADSGLPAMCFGYLLDNSQSKSSAVLPGRVASLKHIRPFVSGKPWPIIFHIEPIGKIADSYCHACAAVFHGIREQVPNQLFEKVAVGLDRTGGVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBT7</accession>
    <name>U1PBT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01707</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89541">
        <property type="protein sequence ID" value="ERG89541"/>
        <property type="gene ID" value="J07HX5_01707"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="254" mass="26856" checksum="0162154F873E07DE" modified="2013-11-13" version="1">MLTNDTAVVTGAASGNGRAIAQRFAEHGSDVVIADIREEPRQGGQPTHELVSDDHDISAKFVETDVTDTDDLDAAVEAAEEFGGIDHMVNNAGIFRAEEFLEVTEEEYEFLMDINTRGVFFGAQAAARRLVENGGGTIINISSVAGLEGSADHVTYTASKGAVRLLTYSLAAKLGPEGIRTNAIHPGLIETSMTTEDVPIFGTEAEEQFIQMVPQRRGGTPDDVADAALYLASDLSGYVNGESLVVDGGMSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC20</accession>
    <name>U1PC20_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01806</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89636">
        <property type="protein sequence ID" value="ERG89636"/>
        <property type="gene ID" value="J07HX5_01806"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2243758_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="12356" checksum="EEAA50F951EEE34B" modified="2013-11-13" version="1">MSLDELSETVTDRYADLGDELGVTLDRETRNELAMLSVALEPDDTDELLRRAVHMLFQTTVDTGKLDFQLRTGFDATYDEYLSGMSYDQMAGGSFPQPQQNDDRRYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCB8</accession>
    <name>U1PCB8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortase related acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01908</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89736">
        <property type="protein sequence ID" value="ERG89736"/>
        <property type="gene ID" value="J07HX5_01908"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087351_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="166" mass="18464" checksum="609DB827A1FB1810" modified="2013-11-13" version="1">MAVSIRVATPNDAERIRDVHLRSIEELGGQAYSETQVEAWAHDRDPGEYPIETETTHVLVAEDDAVLGFGWLRYDAGEHLQALVDGEIVAVYVHPSAARRGVGSQLYSALEAEADRRGLELLGLWASLNAVPFYKTHGYDRVTDHALELRAGVELTVTELRKRLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCM0</accession>
    <name>U1PCM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02008</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89836">
        <property type="protein sequence ID" value="ERG89836"/>
        <property type="gene ID" value="J07HX5_02008"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1726045_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="16903" checksum="18E0D934EDE14E01" modified="2013-11-13" version="1" fragment="single">SRVDRLRAQLVDDPPVGTGIGRSVYPLPETSYTHGRYDEYVLKLPSPDYHDSYGYERDGRVQNRAEAALWSDCRSPTAWLVPVVAADQRGHWLIMPRGESIDSDADWLDAWTARVVEAHGLSSSHGHDIDPQNIVRLNGDARLCDYGLLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFJ5</accession>
    <name>U1MFJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00025</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87884">
        <property type="protein sequence ID" value="ERG87884"/>
        <property type="gene ID" value="J07HX5_00025"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_12_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031725">
        <property type="entry name" value="ASMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16864">
        <property type="entry name" value="Dimerisation2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Dimerisation2" evidence="3">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_2" evidence="2">
        <location>
            <begin position="128"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="359" mass="39574" checksum="F517E8D41B9357B7" modified="2013-11-13" version="1" fragment="single">MSNKSSSSDGASNIDTSGERAAKVGELLGMREFWSGQILHAGVKLGVFELLSDAPLAADAVADELGLEPAYCYRLLRALASLEVLETHDDRRFALSAVGELLQADHPDSLRDDVLFWRSPEYLRSALHLPAIISEGGTSGFAREFGCTIFEYAEQNRAFGAVFNGSQATPSQWMTPLVLGAFDAYEFGRVSHLCDVGGGHGHTLCHLLAEHAHLEGTVVHLPNVIDTEPDHWAGRLGVTDWCQYVVGDMFQTVPRADAYLLKFILHDWPDSECIEVLSTVREAAPKHCRVFVIERLVPEDGRSLAVTRADIEMMAVNDARERTEAAYQSLAEQAGWEFVQTRTQQDETLSVIELRMADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFM3</accession>
    <name>U1MFM3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00075</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87934">
        <property type="protein sequence ID" value="ERG87934"/>
        <property type="gene ID" value="J07HX5_00075"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2299239_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="11096" checksum="AE8E4B7F582DABD5" modified="2013-11-13" version="1">MCVVLSECLSGDREFRTTNATILPAIIRVLLRFSTPVVSNFFRVTERNCNHSSEHERGFYHLDLGVDGIVDTEERVGIEDGPDDDLAGVSVYPSNGVLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFP1</accession>
    <name>U1MFP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00105</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87964">
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        <property type="gene ID" value="J07HX5_00105"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2270942_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="102" mass="11316" checksum="1F5F4BB94552B528" modified="2013-11-13" version="1">MIDIKTGDSALRITSLNDDLLVIDVDGWNKDETVVEPDLHDTIPVDEVVSGRLKRLRVSASSLNLMSSEVELEEHVGETXXXXXXXSHARVHNTVCSLNDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGN9</accession>
    <name>U1MGN9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00513</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88369">
        <property type="protein sequence ID" value="ERG88369"/>
        <property type="gene ID" value="J07HX5_00513"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2418096_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="93" mass="10066" checksum="62576CEC1C719D19" modified="2013-11-13" version="1" fragment="single">MSRRHSRRAVLAGGASAVLGGLAGCFGQGGGSSDPASMQVSFRDWLVAPELTPGITGNKNRVYRFEYIPGGFLSQTEQDRIQVEHQCSILTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH24</accession>
    <name>U1MH24_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S17e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps17e</name>
        <name evidence="5" type="ORF">J07HX5_00720</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88574">
        <property type="protein sequence ID" value="ERG88574"/>
        <property type="gene ID" value="J07HX5_00720"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_176720_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_S17e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="RPS17e-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="PTHR10732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="SSF116820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="63" mass="7135" checksum="95B35349BAB18E86" modified="2013-11-13" version="1">MAIKPAYVKKTGRQLIEQYPDAWGPEFEHNKSVVMEVTNIESKSVRNRIAGYVTSKYNTSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHA1</accession>
    <name>U1MHA1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Citrate lyase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00830</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88684">
        <property type="protein sequence ID" value="ERG88684"/>
        <property type="gene ID" value="J07HX5_00830"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044864_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="4">
        <location>
            <begin position="4"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="292" mass="30533" checksum="81F486D041395D06" modified="2013-11-13" version="1">MIRRSVLFSPGDQPELLRKAATTDADVVVFDLEDGVGPEQKPQARKAVAAAVAELDPETELCVRVNPPGSGLTADLAALEPLPESVMLPKVSGPEDVAAVTAHRSIPVLALLETAAGVLAAERVARAEPTDALVFGAEDLAADTGARRTTAGTEIEYARQRVVLAASAAEIDAIDTLFTDFEDTAGLERDATTAAEFGFDGKMAIHPSQVPVINDAFTPEPAQAAWAARVLRARAQTNDAVFAVDGEMIDAPLLARAERIRARAEAAGVDIDGSAGSSEFDEDTNPTPAPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHJ2</accession>
    <name>U1MHJ2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00935</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88789">
        <property type="protein sequence ID" value="ERG88789"/>
        <property type="gene ID" value="J07HX5_00935"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3413619_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="27" mass="3133" checksum="654D92D4F8A26777" modified="2013-11-13" version="1" fragment="single">LGVGFSYEGKWFETRSLRVRVDVTSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHM9</accession>
    <name>U1MHM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ornithine/acetylornithine aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00980</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88834">
        <property type="protein sequence ID" value="ERG88834"/>
        <property type="gene ID" value="J07HX5_00980"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="312" mass="32787" checksum="3787BE56E7605CDB" modified="2013-11-13" version="1" fragment="single">MSGFVFSEKPIRLVEGNGAVVVDDEGREYLDMGASYACVPLGHGHEAVQTAVRDQLDALTFVQASYPVAARTALYDLLAETAPADVDNVWLCNSGAEANEAALKFARSATGRSKIVATMQGFHGRTMGALATTWKDKYKTPYEPLIGDVEFVPYNNPAAMADAVDDETAAVIVEPIQGEGGINPGSKKFLQTARVETATSGAALILDEVQTGLGRTGRLWASDRVDVVPDLLTTAKGLGNGLPIGGTLCRDWIAEAHGSHGSTFSGGPVVSAAAGATVSTLVDRDLPAHAAEIGRYLRDELSTLENVRAVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHR4</accession>
    <name>U1MHR4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01000</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88854">
        <property type="protein sequence ID" value="ERG88854"/>
        <property type="gene ID" value="J07HX5_01000"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043611_0_1_2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="308" mass="32450" checksum="6802B9189D18A562" modified="2013-11-13" version="1">MLSALLNAVPVSRGAIQPYLALIRVQFLSFTVVVVSLPAAVAVEAGVFSPANTVFALGSVLFAHIAVNTLNLASDYRTGIDAETDETPYSGGNDVITNNTLSYRRALFVGTLSIVLSASFVLPLVLSFGAPVLLFYGVGITLVVGYTDVFARVGLGETACGLGLTLLPTIAVGYIQAGRVLEPLPFLGVPMFLIGFNLLLLNELPDVAADSSNGRVNIPIVLGRQRAGELYFVLVAALVGSLLYLVWTNDLPVTVLVALLPVVLLASVFDSIVLQRDPELTEAELAKHILWTQATIAGLTAGMLLTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHS9</accession>
    <name>U1MHS9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01015</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88869">
        <property type="protein sequence ID" value="ERG88869"/>
        <property type="gene ID" value="J07HX5_01015"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3352252_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="37" mass="4177" checksum="1AD765CC174C28CA" modified="2013-11-13" version="1" fragment="single">ETVTLAGLSFERDDRVLIARQDGTRIPIARYRLDDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHY7</accession>
    <name>U1MHY7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator containing CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01097</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88949">
        <property type="protein sequence ID" value="ERG88949"/>
        <property type="gene ID" value="J07HX5_01097"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982154_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016427">
        <property type="entry name" value="UCP004699_CBS/ParB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004699">
        <property type="entry name" value="UCP004699_CBS_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="60"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="119"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="310" mass="34189" checksum="471B618D107ED9EF" modified="2013-11-13" version="1">MFVVDDRVRVVLADPDANRPLDRQRRLLGLVEIRRRQVGXXXXXXXXDTDTDKPTVETYMSRDVATAAPDDTVGEVARRIAADDDHGGFPVCNGRHVEGFVTAHDLLLEADHEPIFKVMTTDMLVAHPAMAVTDAARVILRSGIRRLPVVDDAGNLVGIISHADVIRSHIERVTPGKVNKLIETLETIHDVDARSERRGVSLAELIPTQAKVYADELEGRKYELERGLAEPLVVVDAAGEQLLADGHHRVTAATELGIDTMEAYVIIIDEPVELGLSKTAADENLYSVEDIEPVDYAHHPLVETTQRLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI06</accession>
    <name>U1MI06_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01124</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88974">
        <property type="protein sequence ID" value="ERG88974"/>
        <property type="gene ID" value="J07HX5_01124"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037612_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="234" mass="25964" checksum="45AEDB9DEE4AE9BD" modified="2013-11-13" version="1" fragment="single">ALADRGEDVLLVDLDAQGNATVGLGFESAYTDAGTSLYDVLLELDNEHRLDEVIRQHAEFDVAPAHVDMFNAEAELQTAMRGRERLWMALDELERKYEFVIVDAPPTLGLLTENALLACRNVLVPALAEVTSKHALDILFEHFETLESGYGVSVDPIGIVINRIEVDGEADRMIEWFEESFGDTMPLWRVRNRVTIKRALAHNASVFGHSERTDMAARFSAIAAHLGTSRAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI27</accession>
    <name>U1MI27_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01154</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89004">
        <property type="protein sequence ID" value="ERG89004"/>
        <property type="gene ID" value="J07HX5_01154"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057266_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="115"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="336"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="418" mass="44086" checksum="819187AF2DB526BC" modified="2013-11-13" version="1">MLAPDGDPDQQPIEYQPVGVTELLSAMKDTSELLVDLAYSALLHNSPALAEEVLVLESRMDRLQLQARMNLLLAARNPTNARQLAPVLGIVGATEKVSEAAGDIATIVLDETALVEAIRGALPEAVEVLARAELASDSPYAGRTLGAIDVETETGVRVIATRRDDDWAVNPDAATTLTPGTVVLLRGAAEPVAAVYKTVTGDSYDCAADDTGNRTDTNTGTGSDHGRGHDHDIADLDRAVDSIVLMKDTSELAVDLAYASVLLDDESLAQEVRSLEVEIDTLQSRLETWTLRAAGDVADPASLRGLLGLADSAELISDAALEIAEGILRDIETHPVIAESVRESEVAVRRLELSTDSPLADSTVAAVTETAPGVAVIAIRRADGDWLFYPDAAVTTAPGDTVIVRGTWTATDELLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI50</accession>
    <name>U1MI50_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01185</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89034">
        <property type="protein sequence ID" value="ERG89034"/>
        <property type="gene ID" value="J07HX5_01185"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_978610_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="138"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="211"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="284" mass="31224" checksum="2E91A70D270568C1" modified="2013-11-13" version="1">MSANSSXXXXXXXNAQELIVEAVRSQATALDRLGESHNSKTSEYDAVVTAQELPDGTGIELTDRIRDRHGDGALPVVLAVSDGGEAIASAAISAGVSEYVSLGTTGSGENGVAVTQCLRDVLANGSRKIVNNASGKTQTAAIRKLTDEIEDVLWLFSPDWERLLFVNDTYEDLWGQPTDRLRAEPMAFLEAVHPDDRLTVERGMERLAAGETVEIEIRGGQGEDERWLRIQGAPIRDDSGEIRMLGGFSRDITDRKQRQRRPRGAAICHERLRRATRRTLCIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI93</accession>
    <name>U1MI93_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit E</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">V-ATPase subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atpE</name>
        <name evidence="7" type="ORF">J07HX5_01246</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 5">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89094">
        <property type="protein sequence ID" value="ERG89094"/>
        <property type="gene ID" value="J07HX5_01246"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120786_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="22072" checksum="7D373CEF5414693F" modified="2013-11-13" version="1">MSLDTVADDIEQRAQERARELREQAEADAEEIREQAQREADEITDQRLAEIEETIEQERERERSNAALEAKQQRLKTRREQLDTVQERVASVITDIEGDRRRELTAQLLADAAADVDEPPAAVYSRAADEELLTELLEEYDGFSYAGEYDCLGGVVVESEASQVRIRNTFDSVYEEVWEANLGTVSDRLFDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIN0</accession>
    <name>U1MIN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01431</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89274">
        <property type="protein sequence ID" value="ERG89274"/>
        <property type="gene ID" value="J07HX5_01431"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1405936_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="21431" checksum="832712B312250749" modified="2013-11-13" version="1">MEPPLLTGTQLHIWTNCLDGHKMGYRLRRTVLGVCRPPCDCAYRCAPIGERWWGLLLITQILDVLFKFVKCLCNLCLCRVANVLCFLCDTLDGVTYTGHDVCVVIRVRHNVMDTTFMDMNKSGATSLKQADCESICVGERSYLGIPEGLNRAEQTAVRSLSQCAIAGLACESVGFDVDPTVLIGQPWDKNLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIZ1</accession>
    <name>U1MIZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01547</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89389">
        <property type="protein sequence ID" value="ERG89389"/>
        <property type="gene ID" value="J07HX5_01547"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_958108_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="290" mass="30351" checksum="12F104D63B71E5C6" modified="2013-11-13" version="1" fragment="single">NRVPEVPPASSAEHRQVFICSAVFDGMSEPDLTVPGNSAAVTAAGSGIGRQIAAHLVDAGVNVAVNDVDADALDATADALAGGPGELRTVAGDASDPTDMDAFVHQAVDAFDGLDILVNNVGVAGPTKPCEEILPEEFMNTLAVNVGGAFNTARAAIPHLREGNGGRIVNISSMSGKRPLQDRTPYTSSKMAIVGFTRTLAVELAEDNITVNAVCPGSVEGPRLRRVIEGQAESQDRSLEDVEQEFRAVSPMDTFVQASDVADTVLFLCSERAERMTGQDLNVTAGIVMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ12</accession>
    <name>U1MJ12_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01577</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89419">
        <property type="protein sequence ID" value="ERG89419"/>
        <property type="gene ID" value="J07HX5_01577"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080639_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="288" mass="30095" checksum="316DE46F72D97875" modified="2013-11-13" version="1">MDSIRRREDTDGCACIRCRSVDPRIFRQSLGGDLLTGTALLGRNPSVAVGVFVALLLTGLLDPLWTQIGQPVSFIDIPAEGVFFLGVLAVVVRTYAVTMFSASMSDQPLSTRELVRYSVARLPAVSVTLAIIVVTSFVALGLASVGASVLFAIALAVEATTGVALAVDSIFSGASATLIFGSVMALVAFKFWLAPEICVAGGYGPLTALWLSWSLTPAHRLRILVVVVGFGVTAFGGDLFTGMLAATGAEAGPDLPGLALVGFVAQGLCYVIWFAVGTQIYFRGVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJB0</accession>
    <name>U1MJB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative exporters of the RND superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01720</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89554">
        <property type="protein sequence ID" value="ERG89554"/>
        <property type="gene ID" value="J07HX5_01720"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_853898_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="155"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="325" mass="34338" checksum="66C556B81589247E" modified="2013-11-13" version="1" fragment="single">GDQADATTPLSLMQTTAASNPEGEFAQAFADAAGTDTTDPSELRELVPEENVPGLFDQLLSETQRAEQFVYVEDGNYEALRVQTAIDASFTASEVASELREIATATEDETSGELGITATGMQVVSDETQDALLSTVIQGLALTTVSVFVFLAGAYRLTGNPASLGIVTLLPVVFSVTWILGTMWLIGIPFNSLTGTITSLTVGLGIAYSIHISSRYELELRRQGDVWDAMETTVTGTGGALLGSAATTVGGFGTLAFAIFPVLQQFGIITGLTIIYAFLASVFVLPSLLVLWTRYLGPSAYFPPHDAETEDADQEPTAADGGRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJF9</accession>
    <name>U1MJF9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01784</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89614">
        <property type="protein sequence ID" value="ERG89614"/>
        <property type="gene ID" value="J07HX5_01784"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148450_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043900">
        <property type="entry name" value="DUF5788"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19101">
        <property type="entry name" value="DUF5788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="17674" checksum="91ABDD19D80716F6" modified="2013-11-13" version="1">MTEDHKHKMKSYQRKQLLERIERDGATVGESIPDQIEIQGETVDLKTFVFEIRRRETIPTGDRDRVKRATRNLRRERLERKQRIEDADTPISYEDGERLADAIVGIDRALGALESLEPVDLEREAQAKETADRKRWTRFLQQALGQTDNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJK5</accession>
    <name>U1MJK5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartate carbamoyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01840</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89669">
        <property type="protein sequence ID" value="ERG89669"/>
        <property type="gene ID" value="J07HX5_01840"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1207583_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="23991" checksum="03600A73E6B4EC87" modified="2013-11-13" version="1">MRMRRTQITSAKQLSRGDIEAVLDRAAEFATDPTAHTDRWPGALLGLAFFEPSTRTRMSFAAAIKRLGGDIVDMGGVDSSSVTKGESLADTARVIAGYADALVVRHPSEGAATMVSEFVDGPLINAGDGAGQHPTQTLLDLYTIRVAACLDGLTIGIVGDLKYGRTVHSLAHALTNFAVEQHFVSPXXXXXXXLPSVSANVRAISSVSAAVSSPSTSSTPSIRGTGFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK32</accession>
    <name>U1MK32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02051</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89879">
        <property type="protein sequence ID" value="ERG89879"/>
        <property type="gene ID" value="J07HX5_02051"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2874943_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="63" mass="6964" checksum="3B919A3939740380" modified="2013-11-13" version="1">MVKSGFVCRTRAAGLDRMDRLRSATETSYTTAEQSDSFVDTVSTQNRSDATVRRDRCCLAAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK67</accession>
    <name>U1MK67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02112</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89939">
        <property type="protein sequence ID" value="ERG89939"/>
        <property type="gene ID" value="J07HX5_02112"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2257440_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="104" mass="11420" checksum="D227AD4521CF8C65" modified="2013-11-13" version="1">MLQNSRGQSVDPVPFVVVTGMTFLWAYSFFPLYLQTLGVGVPIGLAAATLIFLPLAAFAYYRLVWNAQLEVRTEVSPGLRFEQIMLQAVIVTGLCLVLTVVLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK83</accession>
    <name>U1MK83_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02137</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89964">
        <property type="protein sequence ID" value="ERG89964"/>
        <property type="gene ID" value="J07HX5_02137"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3128455_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="49" mass="4853" checksum="52D39380C22F87CF" modified="2013-11-13" version="1" fragment="single">TIEPAFAGLLVVGSVLDTDIVSQTVFVVTTTGIAVGGIIGCIFNTAITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MUY8</accession>
    <name>U1MUY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein conserved in bacteria (DUF2309)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00006</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87865">
        <property type="protein sequence ID" value="ERG87865"/>
        <property type="gene ID" value="J07HX5_00006"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079269_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018752">
        <property type="entry name" value="DabA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38344">
        <property type="entry name" value="PTHR38344"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10070">
        <property type="entry name" value="MpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG87865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="305" mass="33817" checksum="962AFBBB05874482" modified="2013-11-13" version="1">MSPEPLEINEQVAAAAESVGAVWPLHSFVTANPLAGFEDQPFDEAVTEAGQLLGGSGYPSVELFRRAWETGQIDPTLLREKLANNGYDDDPEQSLNRMAAGTADECEREDKNRNADEDKDRSTVTTATDQVDAVLTKWLSVFLDQGQAEWSMPAREQGFYTAFRAVARHDTEIPDRSAIAAAPDSPAEAIRTVLVDHSVERERWEAILEQQLTALPGWTGLIKRRAAGGGAWQSAAPITLVEXXXXXXXXLRSSSSHTNHRRIGHAQRGWRHEFAHNTNKSWMCFLHPHGRPVCRVLRLCIRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV62</accession>
    <name>U1MV62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00116</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87975">
        <property type="protein sequence ID" value="ERG87975"/>
        <property type="gene ID" value="J07HX5_00116"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2313684_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10325" checksum="A41D4EF052366F15" modified="2013-11-13" version="1">MVTALLASVAVFAAALLLGFGLERRLGSDATLEALPWYLQLLVGGLSIAPLTYLEAQFTVGPADGLVVAFAISAVCWVSLPALLSRLVDYDETATPQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV96</accession>
    <name>U1MV96_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00161</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88020">
        <property type="protein sequence ID" value="ERG88020"/>
        <property type="gene ID" value="J07HX5_00161"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162429_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="125" mass="13442" checksum="6DF1DCE4CAE47E98" modified="2013-11-13" version="1">MDCPRCGGPLSTFAVETTDRSAVVCEACGFAGVAASHRGEERNPESWERAVERFETADVSLEQSRQTGRADAVSVPTDDSDSRIDAAALEESVTVASALREREAERDRESERSQDATETEGSSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV97</accession>
    <name>U1MV97_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00009</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87868">
        <property type="protein sequence ID" value="ERG87868"/>
        <property type="gene ID" value="J07HX5_00009"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2930077_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="60" mass="6476" checksum="18324AC12C819710" modified="2013-11-13" version="1">MTRAGPGHIFLVHTINKDVMFFGSISNKTGKSTELSSVEFPVPRLTPVPRIVTAAFVSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW33</accession>
    <name>U1MW33_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferases involved in cell wall biogenesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00336</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88193">
        <property type="protein sequence ID" value="ERG88193"/>
        <property type="gene ID" value="J07HX5_00336"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="196" mass="21107" checksum="AF032940C636070B" modified="2013-11-13" version="1">MTNGRAEIVCVDGSTDATAAIARDRGARVIEQAPRGYGVALKRALRAADRPVVVTTDCDDTYPMVRLPRFLALINAGYDVVSGDRLYHGADAMPAANRVGNHLFAAVASALLGTRVHDVTTGMRAYRHEVIESISWSENTGLSAELLMRPLLRGHNVTECPIRYGNRRGASTLDPLRGGAAIAKSILTVGLNERLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW62</accession>
    <name>U1MW62_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">J07HX5_00366</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88223">
        <property type="protein sequence ID" value="ERG88223"/>
        <property type="gene ID" value="J07HX5_00366"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="94"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ERG88223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="244" mass="28165" checksum="2B160B164399FEA2" modified="2013-11-13" version="1" fragment="single">MVENVASEMVELEAEDFYLLSGIEQGMRFSEWVAREKLPEYSQLTGEDVSYRIDRCETRDLLERNTIQYEGYRLTFEGYDALALHTFAERETVSGVGAPLGVGKESDVYEVRASQPYALKFHREGYTEFRAVDREREYTADHDHVSWLYTARKAAEREYAALETLYPTVSVPRPVDQNRHAIVMERVDGVELDRADLEDQQVVPVLELVLQEMTTAYDEGYVHADMSEYNVFVDTDGVTVFDWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW90</accession>
    <name>U1MW90_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00514</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88370">
        <property type="protein sequence ID" value="ERG88370"/>
        <property type="gene ID" value="J07HX5_00514"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3054600_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="53" mass="5077" checksum="CB21312A07DDC76D" modified="2013-11-13" version="1" fragment="single">SERLLVSVAAETVVTALFGSDPGSAAWAGLGVSAVAVGVPLGALLAAADVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWI5</accession>
    <name>U1MWI5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TYR_PHOSPHATASE_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00635</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88490">
        <property type="protein sequence ID" value="ERG88490"/>
        <property type="gene ID" value="J07HX5_00635"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1736348_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="16303" checksum="26428212117126D6" modified="2013-11-13" version="1">MSNPAVRPVGYVEDDPVIRRIGERNLYLGNKHAAAPEQHDQSFRYVVSVSTEDYPLTTHHHPLDDGPGNDWATFASAVDTARKLLQQDDSVLVHCAAGISRSSTVIATVLAAEEPQSLRESLSTVLQARPSATLHPALHELAVVYLAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWN3</accession>
    <name>U1MWN3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00701</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88555">
        <property type="protein sequence ID" value="ERG88555"/>
        <property type="gene ID" value="J07HX5_00701"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_3_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="5">
        <location>
            <begin position="307"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="382"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="419" mass="47827" checksum="30772BDE2EA78E8A" modified="2013-11-13" version="1">MEVRRTAPVKLDVPNQRREDFHKSAKQFLHCANRAAEFCWNDTGYEQCITANSTARSALYDELRAETDLTANLVQAGIRRGVQAVTSCVERWKQGKRVSQPEFTSWSMVYDKRSATFYRNKVSLSTVNGRVECDFELPSDSPTPYEEYVLSEEFEFRASTLQYDEVTDEFYFHITTLKYNSDSDNTTNTEVPADTGHQTVLGIDLGVNSLAVASTGQFWTGDEYDHWCREFEKRRGEMQQRGTQAAHNALLRLGKRETAWRKQHLYIIANEIVTEAVENDCDVIVFEDLSDIRERLPQANWHHIWAFRRLVEYVEYKAPEQGISVEKIDPSHTSQRCSRTDCGFTHEDNRNGEQFCCLKCGYEVNADYNAAKNVGTQYARKQTHRLRSSPKSPGGDAPVNVRITGGTLNGESHQPIAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWT7</accession>
    <name>U1MWT7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00583</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88438">
        <property type="protein sequence ID" value="ERG88438"/>
        <property type="gene ID" value="J07HX5_00583"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_8_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="127"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="388" mass="42514" checksum="5F000153831CB3F7" modified="2013-11-13" version="1">MLDYVGLETDLEPEDRLVRDTAREFVEEEIEPIITDHYTAGTFPTELIPKMGELGFYGATLETHGLPGVSQTAYGLLMQELEAGDSGIRSMASVQGALVMYPIAEYGSDTQRDRWLPELKTGEAVGSFALTEPNHGSNPGGMETTAEPARDGDGYVLSGQKRWATNAPIADVILVWARDQSDDDTVRGFLVETDRDGLTTHSIDDKLSMRASVSGEVELDNVAVPSASRLPDVAGMKGPLSCLTQARYGIAWGAVGAARNCFETAREYATDREQFGGPIARFQLQQEKLAEMATQITTSQLLAHRLATLKERDDLRPQQVSMAKRNNVRMARDQARVAREMLGGNGITADYPPMRHLANMETVYTYEGTHDIHSLILGEDLTGIPAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX53</accession>
    <name>U1MX53_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PEP phosphonomutase related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00709</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88563">
        <property type="protein sequence ID" value="ERG88563"/>
        <property type="gene ID" value="J07HX5_00709"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="352" mass="39268" checksum="27ACB6AD906E9497" modified="2013-11-13" version="1">MTNNTDEVASRVRSTAPFVRDLDNPAAEQFRSLLEDQEYVFAPGLYHALDARLAEMAGLNAVYMSGYSTVLGQFGYPDLEMVDMGEMVENAERIVEATELPVVADADTGYGGVHNVRRTVREYEKAGVAAVHIEDQTTPKRCGHIAGKEIISRADAEARFSAAVDAKQADETVIIARTDAYGSANGDWEEHLARGRLYADCGVDLVWPEMPDPSREDAIRYAERMHETHPDVSLAFNYSSSFAWSEEENPLTFSELGALGYEYIFVTLYSLHSGGHAVYEDMKNVAENDEQAQFDLEQRYLGHETESHHELSFVPRFQEVEAGLDPAAQRRQEASEGFTNETEETVITTEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXB1</accession>
    <name>U1MXB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00774</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88628">
        <property type="protein sequence ID" value="ERG88628"/>
        <property type="gene ID" value="J07HX5_00774"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="202" mass="22877" checksum="CC159B700D72BB79" modified="2013-11-13" version="1">MGIYDRYLAGRIRLADATLPKTVALVITERDLLTDDAFTTLREWFDWAFGYDAEQAVVYVSVLDEAAVPQLRSVLESLTAPRGMAVRTPGDDTPVDAPIQVSIGLGGQHEFATAVQSIATDIANSELSTDQITETAIERRLVFPAVPDLVVKTGSERLSDFMVWQSAYSELYFTDVNWEQFRRRDYLRALRDYQTRQRRFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXJ7</accession>
    <name>U1MXJ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01001</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88855">
        <property type="protein sequence ID" value="ERG88855"/>
        <property type="gene ID" value="J07HX5_01001"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_611991_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="424" mass="44464" checksum="A94954E3F0C2DB2D" modified="2013-11-13" version="1">MSTRLMLAVVSRPPVQRGTHTAFGVYVVVLATAYYYNLTLVQLGVTDIGMQRLGLAMEVVAAAMGLLALVTLAVTLLSGTLIDRWGWGARTVRKCRVLFGIVLLQIGVTALLPAVASLLGFLLWIVACAVLLGAAIPVAFSLMIDLVAPSLRGYAAGTVTGCAFALAVLVPYEWAVGNFVPAAVAVLSPAAVVLGVVAGAPRLVDEPGDQTGRGIDGTRTNEPIRGRSWAVTAPLVGGVLLLFGAFFIDSLGFVRIIEQAQYVETSWQSSAITVRGTLAGTHIVGGLAAGAVYTKRRPLWVFAAAFALFGLAQCLYVYDIVVGGPSVLTTIIPLVYILAVSSYTTVAFALWPDLATTETIGRYTAVGIGVGAWTATFSSTALALVSELVQLQIAWHLAVVAGLSAVFLLLTARMWSLTADIDTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXM8</accession>
    <name>U1MXM8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mevalonate pyrophosphate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00909</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88763">
        <property type="protein sequence ID" value="ERG88763"/>
        <property type="gene ID" value="J07HX5_00909"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040369_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="323" mass="35008" checksum="F88F581BAB8905CE" modified="2013-11-13" version="1">MQATAIAHPIQGLVKYHGMRDAEQRLPYHDSISLCTAPSHTRTTVAFEPDRDADEYVVDGERVTGHGAERIRTVIDHVRDRAGRTERVRLQSENSFQTNIGLGSSASGFAAAATAAVEAAGLELSRPAISTIARRGSASAARAVTGGVSQLYTGLNDEDCRAERLELPESVSERLRVVVGIVPAYKETEQAHREAAASHLFEGRLAHIHEQIAAMRDAVRAGAFRELFELAEHDSLSLAATTMTGPAGWVYWQPATIEILNTVRALREEDVPVYFSVDTGASVYINTTDAFVDRVEAAVADCGVETRVWKLGGPARLVDDALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXT9</accession>
    <name>U1MXT9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type phosphate transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01103</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88955">
        <property type="protein sequence ID" value="ERG88955"/>
        <property type="gene ID" value="J07HX5_01103"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033621_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="13499" checksum="80B3F58C36666F0E" modified="2013-11-13" version="1">MSAQEALKAVPDSLREASYGMGASRWQTIRSVVLPEAVPGILTGTILALGRAIGETAPLIIISVPTTTFSPPEGLFSSGAALPLRIFSSSANFAPEYRTGVVAALAIVLLALMLTMNAIAVIIGNRYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXZ3</accession>
    <name>U1MXZ3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01014</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88868">
        <property type="protein sequence ID" value="ERG88868"/>
        <property type="gene ID" value="J07HX5_01014"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2985534_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="57" mass="6222" checksum="21A294189B3204EB" modified="2013-11-13" version="1">MELSDLDKITVGTVVVSLALFVAAGVAIYDERAFAGIMLALAGFIGAMYFEYRRFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY13</accession>
    <name>U1MY13_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC-type sugar transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01044</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88898">
        <property type="protein sequence ID" value="ERG88898"/>
        <property type="gene ID" value="J07HX5_01044"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_958107_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="291" mass="32451" checksum="AFF52BB1C3CED2AB" modified="2013-11-13" version="1" fragment="single">MDRSVADGIKSRRELLAAGAGATAGLFAGCVELPGLSVELRQFDGSDPLVTYNRIGKGSTKLSYWTSRFYTPAKSGNTQPELSPLTGPFLRTLREQSAQPAATPTLRTQHEEWAREHPGYRIDISYPESADWKARLSTQPPDGSTINNPWITDLDDQLQPLDEYVSGVDDFFPFVRERTVQDGSMLAAWKYTDCRCLYYRQDLIDSYADGDPPRTWDELAAVGREIADKEGIDGFQFRPATSTTIPFFWGQGGQLIDATGEVVLSRPDNRQAMQRTLSFLRRLIETGASPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY69</accession>
    <name>U1MY69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01113</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88963">
        <property type="protein sequence ID" value="ERG88963"/>
        <property type="gene ID" value="J07HX5_01113"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_550552_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="495" mass="52184" checksum="692FD02A0EEC14E1" modified="2013-11-13" version="1">MATEPETLQRGGLFRYDELRGKLFELVLIAATLVGLIALVLLFGFVFLDAIGPLSASAEWYLLFFGTVVMPMSAFTLYSRRNPTVRNTNARAFAAVFGGLALSLSAFVVLDAIDPYGPLTYIITVGGLALSVVAYGRYTGAQYIVGPAVVLTALLAVIWTVGSEVLLFPLVGVVFAIGDQCLGWIPALGSVPVPVGRGVIVSTIGVGIPTLAVAYSSLRERRSTDRVALVLAVMTLSAAGVAGVDRLLRPYLEGLPAWVAFGSVIGAPVVATLALVGARRRGLRSGLVTAAAAVSGALAVGTVASVLSINPRLLVVLTFGMGVPTAYVVSKAIVTDRDGKVGVTGPFILIGGILLGAYLEQALSVTGPDTWVTLTLIXXXXXXXRGPRPDDQRGGRRCLPSPRRAGRKRDHGRAAAGRAGRAGRSVSRPWPVCICICVCRAAGQNQDRNAGRRSEDPELNAPERIKGCLECHLGSAGRVDGRRHRRLEVGERPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYQ6</accession>
    <name>U1MYQ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01463</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89305">
        <property type="protein sequence ID" value="ERG89305"/>
        <property type="gene ID" value="J07HX5_01463"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023330_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008201">
        <property type="term" value="F:heparin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000266">
        <property type="term" value="P:regulation of blood coagulation, intrinsic pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015555">
        <property type="entry name" value="AT-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF53">
        <property type="entry name" value="PTHR11461:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SERPIN" evidence="3">
        <location>
            <begin position="73"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="453" mass="49702" checksum="9011D2B035FB3CBC" modified="2013-11-13" version="1">MRRRRLLAISGALLAGAVAGCAGASDQPNPNEAENPSNGVPVERPERAPATALTSLDNAALETLVAQTNGFTIDLHRQLLADRGDENVFSSPISASMAFAMTYAGARGETRQQLREAFRYPEEDLHATMGKLQSQLDKRGSENDTGGDTDDETEETPFQLSIANSVWGQKSYSFRQEYLDTLAEEYDTKLNKAEFIASYEDERERINGWVADETDNTIEQLLPQGALDSRTRLVLVNAIYFLANWTHAFPEEATTDKTFTTLDGTDREVPMMRLEREWAYAEHDGVQAVELPYVGDDTAMLTVLPPTGGFEEYEQRLDAQQLAGLIDELEPRSGTVRLPRFEFTTSVQLSDPLETLGVTDAFDPGQADLTGVANPEETEEDLYLKEAYHDAAVAVDEDGTKAAAATGSVIGETSAPANPFEFVADRPFLFVIRDRPTGTILFLGRAVDPAGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYT2</accession>
    <name>U1MYT2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01347</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89193">
        <property type="protein sequence ID" value="ERG89193"/>
        <property type="gene ID" value="J07HX5_01347"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2204029_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11257" checksum="928CAC5F003DA4FC" modified="2013-11-13" version="1">MTAVEVALDWVPNTNHTGIYWALANDYYEAAGVDVTVRSPAADDYEMTPAKRVATGASTVGIAPSESVISYQTHPDYSPVIAVAAVCQRDTTAIAAPTTTGVERPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYT8</accession>
    <name>U1MYT8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01493</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89335">
        <property type="protein sequence ID" value="ERG89335"/>
        <property type="gene ID" value="J07HX5_01493"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3176700_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="46" mass="5270" checksum="19A698B0403832E4" modified="2013-11-13" version="1" fragment="single">AGSIEYARMTANELIESGKTHLRTLPENAARARLFEIADYLVEREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYZ1</accession>
    <name>U1MYZ1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01533</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89375">
        <property type="protein sequence ID" value="ERG89375"/>
        <property type="gene ID" value="J07HX5_01533"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802059_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="6719" checksum="B7BADDD7B4C8F1F4" modified="2013-11-13" version="1">MMTHIRAAFRRKDPGALLAVGLVLSVAGLVTAGDLTDQGIGLIVGGAVQAVGVGTMVGTAVWSDIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYZ7</accession>
    <name>U1MYZ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01543</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89385">
        <property type="protein sequence ID" value="ERG89385"/>
        <property type="gene ID" value="J07HX5_01543"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1573839_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="170" mass="18168" checksum="8558492FC04A16E8" modified="2013-11-13" version="1" fragment="single">EAPRGYQGRLPVPPAGITNRSPTEVYRTAFTWTSLELMSVASNICPRCAATVTTELNVCETHDATDGPCSSCGTTYAVRLVAACTNCIYSAGCAAAWGVVSTTELLTFLFEHDLNPVAPGAARRLDAVINEYGEQIHSTDPFRAEFSFSIDGDQLTLAVDETLAVVDTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZD5</accession>
    <name>U1MZD5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylsulfatase A related enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01736</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89570">
        <property type="protein sequence ID" value="ERG89570"/>
        <property type="gene ID" value="J07HX5_01736"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_14_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="51752" checksum="3F6FBDBB6EE9CC43" modified="2013-11-13" version="1">MNTILITVDALRADHLKQYGYHRDTIPTLDRLCESGVVFTHAFANAPYTRVSVPALHTSARLAHTQLASLPTISSELGSTGMTTACLGTRTGFKSAEGDLKFDQYVALGRDEYYRESNSSNRALTQIKDRVMSTVSGLTESHTSIQRLTQIVYDSFPTLAFRYKGYTSAKEVTDKAITWLNQNSHEDFFIWLHYMEGHRPYGVHVDVPEYTTSISNERIRTLMKKAGTTPDTVTTEERELLVDLYDSDLRYFSDQFERLLDTLDELNLRSNSNLIFTSDHGEEFYDHGEYFHRNLPYDTNIQVPLIIDSPAVERSKITSQRELIDIAPTVLNLHDQEPPETFEGIDLFSDTPRKIISTGSQRHPDPTIAVRWKKYKYIYTPRQEYLYNLADDPSESQNLATDRPNIRAEYRRTIPERYFNKNIQANLREPEDEIDRERLEALGYLETKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZJ5</accession>
    <name>U1MZJ5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01627</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89468">
        <property type="protein sequence ID" value="ERG89468"/>
        <property type="gene ID" value="J07HX5_01627"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_8_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="163" mass="17711" checksum="3CDBBA2DB42AFF9E" modified="2013-11-13" version="1" fragment="single">MKQPARRVDRVPPSGIRRFFELAEEADDVISLGVGEPDFSAPWAARNAAIEALERGQTSYTANRGWRALREAIATHVTRYDLAYDPDEEVLVTAGGSEAIDLVFRALVNPGDTVAVAQPSYVSYEPGVLFAGGDVLSVPTRPADAFRLTRDQLRAHGADEAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZN0</accession>
    <name>U1MZN0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01836</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89665">
        <property type="protein sequence ID" value="ERG89665"/>
        <property type="gene ID" value="J07HX5_01836"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_215620_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="4089" checksum="5CF2A22C3C4CE019" modified="2013-11-13" version="1" fragment="single">IRDDQQEWLEENQLNLSAFLRDRLDDKIEQRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZN4</accession>
    <name>U1MZN4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01841</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89670">
        <property type="protein sequence ID" value="ERG89670"/>
        <property type="gene ID" value="J07HX5_01841"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1820946_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="15254" checksum="2594A90F432373AA" modified="2013-11-13" version="1">MNADNLGRSVCCARNTRNRECTRVRSEYNAVVGGRIECSKHIAFDLEVLDNGLNNNIGRPERLQIGCSGHAVLCACGLALGENVVSHQRVEPGRNPVESVLDVGLFDIAQHDLVAVCRRNLGNSAPHRAGADDTDSLDCRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZS6</accession>
    <name>U1MZS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01887</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89715">
        <property type="protein sequence ID" value="ERG89715"/>
        <property type="gene ID" value="J07HX5_01887"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1425052_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021516">
        <property type="entry name" value="DUF3179"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11376">
        <property type="entry name" value="DUF3179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="190" mass="21166" checksum="F04C072C0BC97D5C" modified="2013-11-13" version="1">MAFRQSQTRCSGRPRRFPRRREGYRTLTDDHTVIGLTDGERARAYPFTILNVHEIVNDTFGEPVIVTYCPICRSGMVAERRVGDEVTNFDVSGLLWKAPRIYSAASEQDGRVFSERDEGVANNGNLVMYDAATGSYWSQMLATGICGEYSGERMTIAPASATTWAAWRDEHPDTEVLLPPPTSTTVDPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1N030</accession>
    <name>U1N030_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">J07HX5_01982</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89810">
        <property type="protein sequence ID" value="ERG89810"/>
        <property type="gene ID" value="J07HX5_01982"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056590_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="97"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="226" mass="23184" checksum="83278FBE0447EFD4" modified="2013-11-13" version="1">MDEAEQEQAKRRAGKSAADAVSSGAVVGLGTGSTAAHAIDRLGERVAGGLDLRGVPTSYQARRRAQTAGIPLTTLAEHTPEVAIDGADQVANDALLKGGGAAHVREKVVAAAADRLIIVVDPSKLREQLAGRVPVAVMPAARHLVADAVSANDGEPTLRQAAHKDGPVVTDDGALVLDCVFDPIHDPGALATDLDTIPGVIGHGLFVGLADEIHVGTPTDLRVRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N052</accession>
    <name>U1N052_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02002</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89830">
        <property type="protein sequence ID" value="ERG89830"/>
        <property type="gene ID" value="J07HX5_02002"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3302613_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4130" checksum="BA4BE30E67B4FF6C" modified="2013-11-13" version="1">MDASVSLELALLGTRFSAASLLLAPLIPASIWRWCVTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0J1</accession>
    <name>U1N0J1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02010</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89838">
        <property type="protein sequence ID" value="ERG89838"/>
        <property type="gene ID" value="J07HX5_02010"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108335_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="248" mass="26879" checksum="2C5747655F3974B0" modified="2013-11-13" version="1">MTQLNSYETASVPVLFDMDGVLLEGRRSRPGTYATATDRAIDELGMEPDGPDRELLREYRCDEAVEAICDAHGVSLSEFWRLKEVKASAVAREQFQTGERQFHNDAAAAVTTAKNRPSAVVSNNRHKTVDFITNRHPIGEAADVVRGRDPTPTGFHRRKPNPYYLTETLEKLGVDTGVYVGDRQKDVLAAHRAGLAGILLARPAHSDTSADAEAGDAEAGDADLLQPDATIASLTELETSLAAIVGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0J2</accession>
    <name>U1N0J2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02143</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89970">
        <property type="protein sequence ID" value="ERG89970"/>
        <property type="gene ID" value="J07HX5_02143"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141587_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="12684" checksum="34AC17BD08ECBA69" modified="2013-11-13" version="1">MDGIVFFATEQHDTVVEFYTALGATVWLEQPDCTILQAGAFRFGFCVRERADTNGIVTFVFENRAGVDDAYDRLGDCVDDPPQYNETYEIYQCFATDPEGRTVECQTFEDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0S3</accession>
    <name>U1N0S3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">30S ribosomal protein S8e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps8e</name>
        <name evidence="8" type="ORF">J07HX5_02086</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2 6">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89913">
        <property type="protein sequence ID" value="ERG89913"/>
        <property type="gene ID" value="J07HX5_02086"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080597_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00029">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020919">
        <property type="entry name" value="Ribosomal_protein_S8e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_S8e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_S8e/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018283">
        <property type="entry name" value="Ribosomal_S8e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="PTHR10394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01193">
        <property type="entry name" value="RIBOSOMAL_S8E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13367" checksum="8564268612B9B570" modified="2013-11-13" version="1">MTNHGRSPRKRTGGRRRPNRDRRKHEIGSEPTETRIGEPSLKTVATRGTEQKVRALQTNTANVATDDGVTDAELIDVVENPADPNYVRRNIVTKGAVIETSEGQARVTSRPGQDGQVNAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3F2</accession>
    <name>U1P3F2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00168</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88027">
        <property type="protein sequence ID" value="ERG88027"/>
        <property type="gene ID" value="J07HX5_00168"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_14_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="34"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="418" mass="43099" checksum="6AEF53C15AA7C1FC" modified="2013-11-13" version="1">MPRQNQSVTTDANTAGERSQEYAEQLWGGHTGRLLLSLSLAWATLQTGRFLLSPLLPTIISDLGLTEATAGVALGMLQLMYAATQFPSGRISDRCDRPAMVVGGIAVLIVAFVLFAGATSPAVFLLSVVTLGVGKGLFAVPSRAQLSDLFVEKRGQALGVYSAGTDVGGLLASVIGVIVTGGTILGLQWLTISVSWRVAFVPVIVALVFVAGAYVAWNREPYQVGLPQSGLFSTLRRLATTSAQREALLAFSLFSFVVGAWVNFLPAYLVATKGFSEATAAGVFAVGFIVGFFAKPAAGRVADRTQRRSVAVAGLLIAAAGLGGVVVAQQLPVVIAAIAVYSLGYKAVFPVVDVLLLDAAPDATVGGDLGAARAVFLGVGAVGPVYLGWTVDTVGYRAGFLGLGVSLLVAAVVLARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3L8</accession>
    <name>U1P3L8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00239</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88097">
        <property type="protein sequence ID" value="ERG88097"/>
        <property type="gene ID" value="J07HX5_00239"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_800780_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="122"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="346" mass="39073" checksum="229C07C9503B70D3" modified="2013-11-13" version="1">MTEQGSLSILIVEDEHDLAEVYKTLLTAKYDVQTAYNGSQALDIVDETIDIVLLDRRMPGLSGDEVLQEINSRNYDCQVVLVTAVDPDFDIIELGFDAYVKKPVSEEQLYTAVDRAHKRAMYDRQLRELLSLQKVKTTLENEKSSFELASSTEYAELESRIESINQDLDTILAEFGTDEFAAAIERTQTVAAHRQGEQRYRSLTEDVLDTARIGTIILNSEFSVVWANEQIEQYFGLDREAALDRSYYEIIDKHYEDVFVETATVDRIRSSCAENSXXXXXXXAYADSSSSCSHRHRTLLSISSLSRPGSSRKTPQSSHRLGSYYQSLILIHGLLISTGCCHRTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Q4</accession>
    <name>U1P3Q4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00280</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88137">
        <property type="protein sequence ID" value="ERG88137"/>
        <property type="gene ID" value="J07HX5_00280"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="9"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="398"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG88137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="426" mass="45278" checksum="0E5203A7ADD084A3" modified="2013-11-13" version="1">MTVTAGPVLSITDLQTRFATEQETVRAVDGVSLELGPQETLGIVGESGSGKSVTARSILGLVEEPGRVHPDSTVRYHDPAFVQQIAREYTDRVRWATADTADQRSADDSFVTITAGSNTGDSITVERGAVDLAGAPDSVVRSARGGEIAMVFQDALSSLNPVYTVGNQLTELLGTHQGLSGTAATEAAAELLESVGIPDPKRRLSEYPHQFSGGMRQRAVIALALACDPTVLLCDEPTTALDVTIQSQILDLFDRLQRERDLSIVFITHDMGVIAQVADTVAVMYAGEVVERAPVDRLFDQPKHPYTRGLLRSIPGLTGDVDRLPTIEGSVPTPTEPPTDCRYAPRCPKAFAECEAIHPEHVAVGASDEDQTETEAGTGTAAGAVDHTHTAACLLYPASEPVDQRVEQHVGADSSGGTNDSLEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3T3</accession>
    <name>U1P3T3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-alanine-DL-glutamate epimerase related enzymes of enolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00320</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88177">
        <property type="protein sequence ID" value="ERG88177"/>
        <property type="gene ID" value="J07HX5_00320"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="8"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="216" mass="22175" checksum="AF7ED7FD0445D989" modified="2013-11-13" version="1">MTVPILEPDQAQKRAAAAAAAGYDHLKVKAGTDPTADLDRLLAVRAGAPDAALKLDANQGWTVPETVQFVDRLQDRGLSLELLEQPVDRDNVSGLARVSKQVAPPVAADESLLTPADAIGLVRANAADVLNVKLGKSGLVGAQSIVEIAQAANLELMIGCMLESAVGIHAAAHVVAGTGAFSYIDLDGNRLLAADVIEDTGPTIDIAGPGHGVEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4G6</accession>
    <name>U1P4G6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA mismatch repair protein MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00526</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88382">
        <property type="protein sequence ID" value="ERG88382"/>
        <property type="gene ID" value="J07HX5_00526"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_4_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
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</entry>
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    </reference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="7765" checksum="E26E19BF0918A0D4" modified="2013-11-13" version="1">MSGLTDPSPLDRARLSVPKLLSAAVERVAFWIVVGAPLLSLLLLATGLESPTTARLFAVVLLLNLVALGISRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5J1</accession>
    <name>U1P5J1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00948</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88802">
        <property type="protein sequence ID" value="ERG88802"/>
        <property type="gene ID" value="J07HX5_00948"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1044295_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="266" mass="27379" checksum="A73C5E2D290ECD13" modified="2013-11-13" version="1">METLSSCYLCGAALNKPDSTYRLGAATVTLCSSCETRLEELLNAADSSLSLADIGSASSSVSGSAETPETADTDRQTTTDSAETHTSSSPAPADASTQTDARSDALSSPAVDTNTPPDAGADEGTEEPATDPQAASGEQAVPDTRPDAASSSESGAEIDTNTSSNTNTNTNTSTEPDTERPSNVPESPATGASGAEHDVEITTREYRTLLRLLQNREFPVERAEIEAVAASAYGYSQAKCAAVIDAAVDRGRLTETDGMLRTGVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P637</accession>
    <name>U1P637_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-dependent carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01162</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89012">
        <property type="protein sequence ID" value="ERG89012"/>
        <property type="gene ID" value="J07HX5_01162"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097442_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="204" mass="22937" checksum="4490AB32155E4B59" modified="2013-11-13" version="1" fragment="single">MATTQTDDSETAYDKLLAQYEQVTNLQHAAGYLNWDQQVTMPDAGTPGRARQLSALSATAHDLLVDDQMGAWLEAVETAELTDRQAANVREIRHSYERETKVPGELAEKITQTAAENQQIWQEAKANDDFATFAPRLERIRELQRERAAHIDPDVSPYTVLYEDSHQYLPLEQMETIFATLREELPPLIEAVAEADTELAAPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P662</accession>
    <name>U1P662_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK-like ATP-grasp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01193</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89042">
        <property type="protein sequence ID" value="ERG89042"/>
        <property type="gene ID" value="J07HX5_01193"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982143_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="63"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="27368" checksum="038F82B175087F7E" modified="2013-11-13" version="1" fragment="single">VAVETTQRSVSLAAPAESFPAVDVGFVYPPRLAEGGVADPLLGVPWVNDREAILRSRQKGETIARLRSAGLPTPETVVVSNPADEATLRAAFDAVGPPVVVKPNATSRGIGVTRVDDIDSFLGVCDYLELVHDYTATGDRSFLVQEYIPQARDYRVTIVDGTVVGAVERRADGWVHNVHRGGHAVSVDLAVEHRSLAEQAAAALGIPWLGVDLLVTDERSLISETNARPTIDDAKYHDGFWTELAELIRRIGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6J7</accession>
    <name>U1P6J7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="17">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">J07HX5_01351</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89197">
        <property type="protein sequence ID" value="ERG89197"/>
        <property type="gene ID" value="J07HX5_01351"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_255364_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006314">
        <property type="term" value="P:intron homing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14528">
        <property type="entry name" value="LAGLIDADG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="29"/>
            <end position="50"/>
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    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
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            <end position="297"/>
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        <location>
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            <end position="321"/>
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            <begin position="35"/>
            <end position="340"/>
        </location>
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        <location>
            <begin position="375"/>
            <end position="609"/>
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        <location>
            <begin position="626"/>
            <end position="698"/>
        </location>
    </feature>
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            <begin position="1062"/>
            <end position="1084"/>
        </location>
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        <location>
            <begin position="1083"/>
            <end position="1169"/>
        </location>
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            <end position="829"/>
        </location>
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            <begin position="791"/>
            <end position="805"/>
        </location>
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        <location>
            <begin position="806"/>
            <end position="822"/>
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            <end position="415"/>
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        <source>
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        </source>
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        <source>
            <dbReference type="EMBL" id="ERG89197.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="1384" mass="151955" checksum="19EE2B867D62756D" modified="2013-11-13" version="1"> </sequence>
</entry>
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    <accession>U1P772</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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</entry>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="153" mass="17236" checksum="00EE87D41874ACD9" modified="2013-11-13" version="1">MAETETTEWQQTLAELDGLETEYEDEGWTTVTIQAGHTGIRLPAETELEDPELVYTVPSDSADKLHAAFDTGEFTQFTVYLDETRSPRYHVLELADPDRSLVVLIAGAVGQDQINRFNQTAQKIIGIYTRFRRLNGTAVGLFRHDDPGVFFPE</sequence>
</entry>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="73" mass="8081" checksum="E4F1503A365BC0ED" modified="2013-11-13" version="1">MLDCWTRLVTWRNGREEYSYFQGHLSSLVSLSLLLCMCGSTSVSGVESPNVSLTDRQGVPTPSMNRVIIPNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7M7</accession>
    <name>U1P7M7_9EURY</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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        <property type="gene ID" value="J07HX5_01728"/>
    </dbReference>
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    </dbReference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8941" checksum="CB14E9D7D618D64D" modified="2013-11-13" version="1" fragment="single">NEQEQVLAGHSKFTQAAEKRARIMSSVGRITRTRSVYVVDRAPRDAVDDTALLEEDEVASIDDPEEFRNLVRDRVDKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7M8</accession>
    <name>U1P7M8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00289</name>
    </gene>
    <organism evidence="2">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88146">
        <property type="protein sequence ID" value="ERG88146"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="288" mass="31166" checksum="0F2A5A665EF5F842" modified="2013-11-13" version="1">MDDRPVDTDEVVKIYEETLAAREPGWDYRGHRSLHFGLYDEDHDDPGSAAINTMRVLSAAAKIAPSDRVLNIGCGAGEDSVWNAKARGASVIGVDIGERQLAAAQENAREHDVSDRTAFRVDDFHELATVDDDSVDVVWALEALCHSPQPQQVLEQVQRVLVDDGRVALADLYVKRQPSKPERTRLRKANDGLGVRVGSVPALRSALTATGFTDIEFRDRTAGVKPSLARRSQFADVAGPVSKALSAVGLGSETRDDVIAGNDQLHELVLSGAVGYFIVTARQDTTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7T1</accession>
    <name>U1P7T1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01787</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89617">
        <property type="protein sequence ID" value="ERG89617"/>
        <property type="gene ID" value="J07HX5_01787"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104913_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043815">
        <property type="entry name" value="DUF5797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19110">
        <property type="entry name" value="DUF5797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="155" mass="17091" checksum="AD151D68BBCD6E9F" modified="2013-11-13" version="1">MALDEQARDRLADILALQPTKNGTLQEQWGLDSGSAVHQYLEAELGEYYYRDEDSLIRATPAAESLVGETTTDQTVVGTRLHRRVLDALPESDAEPQSVVATLHAVRETGDDPGVDAVRSALHELVDRGVVERLERTVPTFRRAVDREAITIAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P838</accession>
    <name>U1P838_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Deoxycytidine triphosphate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01899</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89727">
        <property type="protein sequence ID" value="ERG89727"/>
        <property type="gene ID" value="J07HX5_01899"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1025274_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HintC" evidence="3">
        <location>
            <begin position="147"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="271" mass="29841" checksum="CBFD3F8DA71A3B1E" modified="2013-11-13" version="1">MLDGNGRRRDTRDTLYTASPEVANRAAYLGTRLGLLTSVYGPSERVTQPPTGADKQADELWAVRIRDGTDKRRQAVPTPSSLLRQYRQRADMQTQEAAERLADASRSRLLKIEDSAHETVTHETLRRLRDAYSEAGVTTTRLDQILRGQVRFEKVTAVEKTDRTEPTYDLEVQPGGRAIENFVAGRGGVFLSNTAGLCDPGYQGQITLELSNLGAAPVALAPDMRISQLTFTELTSPAERPYGEDRGSKYQGQKGPQASRIGGDREFGGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P850</accession>
    <name>U1P850_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein involved in propionate catabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01909</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89737">
        <property type="protein sequence ID" value="ERG89737"/>
        <property type="gene ID" value="J07HX5_01909"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026574_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="PTHR16943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="SSF103378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE_PrpD" evidence="2">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE_PrpD_C" evidence="3">
        <location>
            <begin position="261"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="48516" checksum="80FD23E4DDABB238" modified="2013-11-13" version="1">MTTTTEIAEFVQTVEYDALPESVIDQLKRRLLDSVGIGLGAIGEEPVTAVRDTVTREGGDAASLWAAGATASPAGAAMYNTTLTRYLDFMDSFLAPGETPHPSDNIGTIIAIGEAVDATGEELIEATAVAYELQGELAWNAPVRDRGFDHVTHTVITQAAAAAALLDLDHEAIRDAVGIAGTAHNALRVTRTGGINEWKGIAAGNAARNGAYAALLADDGMEGPKNLFEGQKGWQQTISGAFEVDLDPACRRVEDTMAKRYVAETYAQSAVEGVIELADLNDIDHEAVTEIHLETFHGAKLIIGGGEGDRHEVETKAQADHSLPYMLAAALIDRQMHNAQYEPDRIQSSDVQRLLRTVTVEEDPTLTERFENGEMPAVIDIELEDGTGYHVEKDAFRGHPTDPMSWSEIEEKFHPMAANVYEQEHRDQIIETVKTLGSKTTADLTALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P862</accession>
    <name>U1P862_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01919</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89747">
        <property type="protein sequence ID" value="ERG89747"/>
        <property type="gene ID" value="J07HX5_01919"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="182"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="358" mass="39165" checksum="014E8CED633DFEC7" modified="2013-11-13" version="1">MNIGFFTDSYFPEVDGVTYTLSLWRDSLEAAGHDVWIVYPDGAYEPDNHEVPIPSLPNPFYPGYRVPLARRLSALPELDVVHCHGPGPAGLLGLVYARRNDVASMYTHHTPIEEYFGQSLPSNRLADLLATAYVPVETALLRQFDVVTASTGRIDRAIAHTELPVGIDMEFFEPTPPARQSNRQPLIGYSGRLSMEKNVDQVVTAARELSACDFLIVGEGPRRETLEAQAPANVSFRDFLPREALPGFYSTLDAFVTASTADTLGLSTLEANACDTPVAAADVPPFTETIGPANGVRFERGDTAAMLTAIDRCVSEPWSPRNAVREYAIGETIGTLEQIYEQLVNAEASRPLLEPPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P874</accession>
    <name>U1P874_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00480</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88336">
        <property type="protein sequence ID" value="ERG88336"/>
        <property type="gene ID" value="J07HX5_00480"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1247587_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="222" mass="24062" checksum="2BF8118BED621518" modified="2013-11-13" version="1" fragment="single">MMTLGAVANQQIVASLVISLVVLVLVWRVDRLVDRYTGAPQQTVTELREFRRVATATIVIAALSWSAEQPVPGWLAEGLETTGTGQLWTALVSFLPSSLVAERVAVFVTLLSTWWAWKFRSVGDGIIERAVARQYDETLAPIVENVWDVGVVVVLILALLDIWGISVTALLAPAGLLGIAVGFAARESIANFFGSIALYADETYERGDFIELENGTAGTVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8C3</accession>
    <name>U1P8C3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00505</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88361">
        <property type="protein sequence ID" value="ERG88361"/>
        <property type="gene ID" value="J07HX5_00505"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1622377_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="164" mass="17311" checksum="8987EEF0E97B66D0" modified="2013-11-13" version="1" fragment="single">LGNATLSVDTPETTAALDDAAPFEVAVPDESWTFANATVTTATVSFELPNSLPSTITTTTATYTDDDRTLVVSQSPVIEGDGIAFNETTLTELATMDTDSELDAEFDAETTTKTIDDREVVITSTDDGTTASWVNDETVVTIATDGDQDALESLIADIEFGADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8D4</accession>
    <name>U1P8D4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00515</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88371">
        <property type="protein sequence ID" value="ERG88371"/>
        <property type="gene ID" value="J07HX5_00515"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100862_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="150" mass="15723" checksum="B831335E58A82B0F" modified="2013-11-13" version="1">MGRLSRLLRGAPARRVGLFVDGPNTFREEFDVAFEQLRAVAAEEGDGTVTPARVYLDEHATPGLIQAAEAHGFAVVTTSGDVDVRLAVDATAGAIRGQFDALVVVSRDIDFKPALERAAEAGVETVAVAPGAHGRSDALRNTAGRAVTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8H1</accession>
    <name>U1P8H1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major Facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88416">
        <property type="protein sequence ID" value="ERG88416"/>
        <property type="gene ID" value="J07HX5_00561"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1457319_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="186" mass="19182" checksum="3FA835679AD48E7C" modified="2013-11-13" version="1" fragment="single">FGISAFAIGWIMAGGKLTKALTQGFFGTLTDQWGHRHYFVATGALLYAAGTAAIPLAAVADGAINPVELTLLPGSQELGGAFFVLFAAYSLLGIADSIRLPASMSLFVDEGTRYDSVASAISLRSVSWKVGQTAGPVIIGLAMDTVSTEAGFLLAAGLIFLSTVGFVITSRRAWASPQPAQPAPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8K9</accession>
    <name>U1P8K9_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="10" type="ORF">J07HX5_02034</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89862">
        <property type="protein sequence ID" value="ERG89862"/>
        <property type="gene ID" value="J07HX5_02034"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2190944_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11905" checksum="9D900CFDE1BB1C3D" modified="2013-11-13" version="1">MCWVIAXXXXXXXGIEVAVEKRPVSAEKVTEIADEVTAELQGRNEQIISSSTVGAAVAERLRDLDKVAYIRFVSVYKGYSDPEDFREVLDSVLADTDTTSSELSDQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8U6</accession>
    <name>U1P8U6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00707</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="13109" checksum="D730119BBC3A58B8" modified="2013-11-13" version="1">MIKSLLVVVCESLQRILLIDRCVGRYGEKRSNHMVYNVNYYFVWCPKYRHAILEPIEDSLKSSFRDVCDESDYEILSLHISSDHVHLFVSAHPKHSPSEIVRTVKSITTRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P986</accession>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="6328" checksum="0CCECFD572F90101" modified="2013-11-13" version="1" fragment="single">HGLYGHPGGVDVPCLRRVPWCVTSATDTRSREPGGSDKADETDRSVVADRLEDLGYRT</sequence>
</entry>
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    <accession>U1P9Y2</accession>
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        </submittedName>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <begin position="154"/>
            <end position="200"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG88901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="200" mass="22592" checksum="6C85D7E5A65F819C" modified="2013-11-13" version="1">MGSSEDSDPVVGVEDPHQFVDRCDFLTEGRCRFAVAHSDVDPAFARERRAKEFRCPVAGDPDESGPTGPWDWADCPHFRCRNHDQDRTCVRCGLEELRVNGEQPLLEEHHLSYDGSESHEITVSLCRWCHATVHDSWGRLADDVTPSQAAIAEREQRRAHQQAELAFESARDRTDRSDRKVGDKSEGEDENENKSESDGS</sequence>
</entry>
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    <accession>U1P9Z8</accession>
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        <lineage>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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            <dbReference type="EMBL" id="ERG88921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="122" mass="13233" checksum="41CDBEB00EC63194" modified="2013-11-13" version="1">MVTACDHCYRSGDAFGAPNAVDPARIVADGRTTAVQRGYNRSRQTVSVCPSTTVTAALLWTTRPPGPCYDRCLVCSFAAARPASRKALIVVASLFHSLTFTTRLRRETFPRALGQLSTEGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA64</accession>
    <name>U1PA64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-dependent carboxypeptidase</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88996.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <sequence length="217" mass="24858" checksum="A1A31158C8ADAF2E" modified="2013-11-13" version="1" fragment="single">EYATPLGSSRMSIHESQSRFWENHIGRTKPFWEVFTPTLNEQLGTAVSPQAAYQTANRVRPDNLIRVEADELTYHMHIILRSEIGKAFMEGDLAVEEIPAAWNEKMETYLGVRPKTDAEGCLQDIHWTSGFAAFHTYTLGSVVAAQLDKAIRADLDVDGLVREGEFEPIHEWMTEHIHQHGQRYKTPALVERATGEPISAEPFVEYLREKFERLYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAI0</accession>
    <name>U1PAI0_9EURY</name>
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        <submittedName>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="129" mass="13894" checksum="8E8D74CEBAA71408" modified="2013-11-13" version="1">MSDKHGASDKSKQTVPLQVGQAAVEAAYADANRTAEPFLAVEQYGEEYAVTYDLLPADEQLTPAATAQLQDRLTAELEAIVADTEEGPAELSKTVSDSLGNVSAFRREQTARQVAAVIADVVLKETNWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAM9</accession>
    <name>U1PAM9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ICC-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01309</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004376">
        <property type="entry name" value="CHP00024_Pesterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024173">
        <property type="entry name" value="Pesterase_MJ0037"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30337:SF5">
        <property type="entry name" value="PTHR30337:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000887">
        <property type="entry name" value="Pesterase_MJ0037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="229" mass="24460" checksum="F91A348D24161514" modified="2013-11-13" version="1">MDALSGVSLQDRAAVIEETLVLADLHVGQAATAVELPVGAGEAMAERLKTLTAAVDPTVVVVAGDLLHSFQGVPEGVSQTLGVLREVVHEADAELIVIPGNHDTLLDAIWDGQTTPAYRIGETVVTHGHVDPEQPAERYVIGHDHPAITIEGNRRPCYLAGDAVYQDADVLMLPSFNELVAGVPVNNLTGGEFLSPLVTDPDAFAPVVRDDETDETLVFPPLDEFRHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAU4</accession>
    <name>U1PAU4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01376</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89221">
        <property type="protein sequence ID" value="ERG89221"/>
        <property type="gene ID" value="J07HX5_01376"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1140541_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="243" mass="26333" checksum="846AC20156FD3315" modified="2013-11-13" version="1">MRDRHTNKCQVARDCRLEGIVKITECLALLVEEADRLDDSLVGVDPGDKIGDLKIGLRRLSETRGDVVPTPIIPGLCSCPTTGLDTYADVGVCSRICHSASMCLCRGWAVARPASGARAVTVRVDRQSQTTDSRGAGSGRLPESLRRGRPQSSSRTRGPCVRVRRASARKHGVEKNASGGHKHPLYGVETLSLTRSGGSSNELQYTRLRRRENTIMLDETEHVKMTGTPGEDNAGRDTSVTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB36</accession>
    <name>U1PB36_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps2</name>
        <name evidence="8" type="ORF">J07HX5_01454</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89296">
        <property type="protein sequence ID" value="ERG89296"/>
        <property type="gene ID" value="J07HX5_01454"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058171_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_A">
        <property type="entry name" value="Ribosomal_S2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023454">
        <property type="entry name" value="Ribosomal_S2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_S2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="PTHR11489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28115" checksum="956C4018C558FB13" modified="2013-11-13" version="1">MSEHEPDESDEPETATVAASEADGSDAEPDESSAGNAPAEPDEADTDTDTDTDTDSQPALDEDVLGDAEADLLIPVEEYLGAGVHIGTQQNTKDMERFIHRVRTDGLYVLDVSRTDSRIRTAADFLTNYDPEQILVASSRQYGRYPAEQFADAVGARARTGRFIPGTLTNPKYDGYIEPDVVVVTDPIGDSQAVTEAITVGIPVIAMCDSNNTTGNVDLVVPTNNKGRKALSVVYWLLANETLDRRGADPAYALEDFESAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBQ8</accession>
    <name>U1PBQ8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxyanion-translocating ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01676</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89511">
        <property type="protein sequence ID" value="ERG89511"/>
        <property type="gene ID" value="J07HX5_01676"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1792050_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="144" mass="16418" checksum="CC6F6CB9DA04F600" modified="2013-11-13" version="1">MADGPGGIKGIEQFGTQIQRLRTRLQDPTRTDFRIVMVPEELSVTESERLRDRLDSFGIPVQTVVVNRVLQDPAAVADVDPDWFVAPDHTDCAFCARRWEVQQRALKRAQGLFRDHAVRRVPLFVEEVHGEKLLRVVAACLEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBX2</accession>
    <name>U1PBX2_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylaspartate ammonia-lyase</fullName>
            <ecNumber evidence="6">4.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">J07HX5_01747</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3S)-3-methyl-L-aspartate = mesaconate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12829"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:36986"/>
            <dbReference type="ChEBI" id="CHEBI:58724"/>
            <dbReference type="EC" id="4.3.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methylaspartate ammonia-lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.2" evidence="6"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89581">
        <property type="protein sequence ID" value="ERG89581"/>
        <property type="gene ID" value="J07HX5_01747"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055277_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00561">
        <property type="reaction ID" value="UER00618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050096">
        <property type="term" value="F:methylaspartate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019553">
        <property type="term" value="P:glutamate catabolic process via L-citramalate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006395">
        <property type="entry name" value="Me_Asp_am_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022662">
        <property type="entry name" value="MeAsp_NH4-lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022665">
        <property type="entry name" value="MeAsp_NH4-lyase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07476">
        <property type="entry name" value="MAAL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05034">
        <property type="entry name" value="MAAL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017107">
        <property type="entry name" value="MAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00007">
        <property type="entry name" value="methylaspartate_ammonia-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
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        </ligand>
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        </ligand>
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    </evidence>
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    <sequence length="417" mass="44227" checksum="4839D0C684965BE4" modified="2013-11-13" version="1">MMQIDRVTATPGVGAFFADDQAAITAGAPSDGFAYDAEPRTAGFDRVREPGEALLVDLTLSNGRVVRGDCAAVQYAAAGDRDPLFRAQAHAETVEKEVGAALIDRDAGALDTNTAVLEELTVHSAVAYGVSQALVAAAAATQETTRTRVLADALGTTPTTSPVAVFGQSGAARRRAAEKMLLKRIPVLPHGLFNNLETMGSEGGRLIEYLSWLSERATELGDGEYRPRFHIDIYGMLKQLFGPPYDRPAVIEYVGALQQAAAPYPLQLEEPMIAATRADQIAAMSELRAGLADAGVDVDLVADEWCDCRADIEAFVDAGAADVVQIKTPDVGSVLESGRAVRYCAGTDTRAYLGGTCNETALSARTSAHVALATDAAQLLAKPGMGFDEGNAIVTNEMRRTLTRHRRSARLGDQKTD</sequence>
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        </source>
    </evidence>
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</entry>
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</entry>
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        <location>
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            <end position="438"/>
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            <position position="1"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89801.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="577" mass="63075" checksum="10FE6DC6D56292FD" modified="2013-11-13" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCU8</accession>
    <name>U1PCU8_9EURY</name>
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="J07HX5_02084"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159741_0_0_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="123" mass="12686" checksum="47B2A77DF468D0F5" modified="2013-11-13" version="1">MVDDRITDGKRIAQLLSSELAGLETGPLAAVAIVDAEPDLEPTADGTLAYRISHDDAVVGHVCCYPDRAVLAGLDWAAVPESNPLEHGPDGLVLADAVAVKHAVDVVRACLASRDGPAGSAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFM0</accession>
    <name>U1MFM0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00070</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87929">
        <property type="protein sequence ID" value="ERG87929"/>
        <property type="gene ID" value="J07HX5_00070"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024306_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="447" mass="49749" checksum="03E2E48A38988195" modified="2013-11-13" version="1">MGLLDRLRSESGPKVAFLGIDGVPYSLLENHFDEFENLAAIAADGAAGAIDSIVPPESSACWPALTTGVNPGKTGVYGFQDRETGTYDTYVPMGRDVQARRLWNRVQAADRESVVMNVPVTFPPEREPDRMVSGFLSPGLDDAAYPDEFQSFLGQRDYRIDVDARLGHEDDKTAFLEDAYETLDRRFEAFQDVITGGGWDLFFGVFMTTDRVNHFLFGDYDRDGQYRAEFLEFYRTLDTYIGRLRDALPDDTTLVVASDHGFTTQEYEVNMNAWLNQAGYLSYRTDDPDELDDIADETQAYSLIPGRIYINREGREPRGSVADGDYERIRDALATALTELTGPDGTPVVADVVRKEDAFRGPHVDIAPDLVAIPAHGFDLKAGFHTDSPVFDTGPRNGMHSFKNTSLFVDNPEVTIGEADLYDIAPTILSLLEVEYDRGEFDGTSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFN8</accession>
    <name>U1MFN8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00100</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87959">
        <property type="protein sequence ID" value="ERG87959"/>
        <property type="gene ID" value="J07HX5_00100"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2204027_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="12305" checksum="6070345AAEACE1F1" modified="2013-11-13" version="1">MLARAPTPALEYALDRCEDRVSGTIFLYLHPHSVNWNYLMQQVTASVDEGGNECLGRSGECTKSDPMNDRIRDYITADTERSVLREERNTIHERSGPRERRLLLNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFZ4</accession>
    <name>U1MFZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00241</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88099">
        <property type="protein sequence ID" value="ERG88099"/>
        <property type="gene ID" value="J07HX5_00241"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2678739_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="8191" checksum="47FF9C35CED8CF97" modified="2013-11-13" version="1">MLRRLVENHVAYTGSDRARELLDSWETAVESFTRVMPDAYAAVISDRTRDDIRRQPPASATPQEAGDAVQGSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG05</accession>
    <name>U1MG05_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="4">DERA</shortName>
            <ecNumber evidence="4">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="4">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoC</name>
        <name evidence="5" type="ORF">J07HX5_00257</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88114">
        <property type="protein sequence ID" value="ERG88114"/>
        <property type="gene ID" value="J07HX5_00257"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_0_2_2"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="4">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="224" mass="23596" checksum="8A90423318F51672" modified="2013-11-13" version="1">MELASRIEHTVLGPTTTWEAVADGLDEANQHGMRACVPPCYVDRATDYAPTVPVTTVIGFPHGHHPAATKRHEAERAQTAGAAELDMVANLGRLQSEEIDAVTADIAEVVAAVSVPIKVIVEAPLLTEATLRRVCDAACTADADFLKTATGVTDGGATVADVELMSEYLPVKASGGVGSWSFANRLFDVGAERIGASRGTTIVREYNQTEEQFSAGAETSATDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG45</accession>
    <name>U1MG45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00312</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88169">
        <property type="protein sequence ID" value="ERG88169"/>
        <property type="gene ID" value="J07HX5_00312"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1954576_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="13581" checksum="31A5F3543339DE33" modified="2013-11-13" version="1">MTDDPTESTAVGADARELNEQPLLTRAKITAAHGRRLGGGIGLFVIVFYILITLVVPPYLPPGEETVSILPVVVVTAFVFETLDSAAGMGIWSDRWRGPLSAGLPTRGGRASVAPVRGGHWACRWAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG81</accession>
    <name>U1MG81_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00357</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88214">
        <property type="protein sequence ID" value="ERG88214"/>
        <property type="gene ID" value="J07HX5_00357"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2745699_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="70" mass="7131" checksum="B2E01602E24708AB" modified="2013-11-13" version="1" fragment="single">FEFQDPAGNVEEAVIDATSSGPTITSGDSTGNLENLDAGEAYDFALRVDADGAPATANVSLDLDITAKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGP4</accession>
    <name>U1MGP4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00518</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88374">
        <property type="protein sequence ID" value="ERG88374"/>
        <property type="gene ID" value="J07HX5_00518"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_23_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18576" checksum="27CE759E0A144829" modified="2013-11-13" version="1">MRATPICSGLLLAVVTTRYPGDPGTPTVRRAGRADLLAVHRIERVSFGEPWPYAAFETFLGTDGFLVAENEHGGVVGYVVANLLADSARQIGHVKDLAVAPTAREQGVGSQLLDRSVAVLNRKGATAVKLEVRESNTPALELYRSREFNHRRTVAGYYADGEDARILIKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGQ7</accession>
    <name>U1MGQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA mismatch repair enzyme (Putative ATPase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00539</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88394">
        <property type="protein sequence ID" value="ERG88394"/>
        <property type="gene ID" value="J07HX5_00539"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1405143_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="20409" checksum="094242FE7517AECB" modified="2013-11-13" version="1" fragment="single">LDATYLVAETDTGLVLIDQHAADERVHYERLRDQVAADTRTQALAEPVQIQVTPAEADRLSTPVHQAALDRLGVRARCVGSTTVAVDALPAPVAETAGPELVGDLLAALTAGPEAAEQTVADAVDALLADLACHPAITGNTSLTEGSAVRLLEALDATENPWACPHGRPVVIQIDNEEIATRFERDYPGHRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGT6</accession>
    <name>U1MGT6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00584</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88439">
        <property type="protein sequence ID" value="ERG88439"/>
        <property type="gene ID" value="J07HX5_00584"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_8_1_2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="5">
        <location>
            <begin position="3"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="6">
        <location>
            <begin position="105"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="PGDH_inter" evidence="7">
        <location>
            <begin position="324"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="531" mass="55058" checksum="2E6C9B13E6325452" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH26</accession>
    <name>U1MH26_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative unusual protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00725</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <sequence length="636" mass="70081" checksum="12F938317CB018BA" modified="2013-11-13" version="1"> </sequence>
</entry>
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    </evidence>
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</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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    </evidence>
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</entry>
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    <accession>U1MID7</accession>
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    </reference>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="133" mass="14475" checksum="A13197C1A1F397B7" modified="2013-11-13" version="1">MNRLAPQHIPLYSSADERDTVWQRCIDDGQPVVAIRDARRGHIVRYDLSHLRVELTPDAVRKLRAGTRSFRSYPTINATDAEEPIGTDPLSAAEGVGGEAGPVSGALHTDSESAARELAVRVSGVLFDASNRR</sequence>
</entry>
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    <accession>U1MII8</accession>
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    </evidence>
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    </evidence>
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</entry>
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    <accession>U1MIM2</accession>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="261" mass="28172" checksum="BD7F3906DD0A1984" modified="2013-11-13" version="1">MTGGQTLRSFFWRAEQLYPDREVVARTSDGPARQRYAEYADRVRQLGNALDAAGISAGDRVGTVCWNTSRHFETYFGVTNSGAQLHTINPLLPTHHIQHIVADAEDRLLFVDPSLAETVAEAATAADADGAFDSVEQFVFMGSSVPDVGLAPATDYESFLADSSTTIDWPALPDDQPAGLCYTSGTTGLPKGVEYTQSMLWSHTMALLTPQAMCIKDTDVVMPVVPMFHVNAWGMPFAATAAGAKQVYPGPSXXXXXXXRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIN8</accession>
    <name>U1MIN8_9EURY</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ERG89284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9564" checksum="5AF4B2E51F19F756" modified="2013-11-13" version="1">MLTRGVALELADEGIRVNAVAPGQIATEFFDGWSEQAVEMVDADELLKPVPLGRAGFPRDVAGAYLYLASDDAGYVTGELLHVDGGWQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIQ4</accession>
    <name>U1MIQ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">rRNA biogenesis protein Nop56/Nop58</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01462</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89304.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="285"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="289" mass="30624" checksum="0B5CBEF58DA6CF4B" modified="2013-11-13" version="1">MTDDAGWFSSLDGASETGSDGGTDGWLEDARSAIATGQADTPADWPARAVTAGAAADTEAYYDQLHDATVAATRALVQEREQADDQQLIHAVRALDDCQRTRNELTERLAEWAGTHGTDVTGDPASVQALADRNPEAPTERRLASLAERIRALAGEAERLRTYIEQTTPPVAPNLAALAGPVLAVRLLALAGGLADLAKLPSGTVQVLGAEDALFAHLQGHAPSPKHGVIYTHEYVRGTRADERGSAARALAGKLTIAARIDHYSGESRPELAAELDDRIERIRARGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ22</accession>
    <name>U1MJ22_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01593</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HAD_sf"/>
    </dbReference>
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        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="193" mass="20156" checksum="0AA430F7BD36034C" modified="2013-11-13" version="1">MTGARVDGAPAAREAFQHRLLSGYGNVISGYERTTLAMASRAQLRRLQPVDTRTDRALARLASAGVDIALITDMPTHVAAAFADVVLDAPVVAVCGTQFETDAAGVFTGAYERLDKGRRAEALSTDHDWDMTVAAGDTNRDAAMAPQADTFLAVAGHGGVHHGLAGEHVPGTLRSVAADQSLGDVLLEQCSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ24</accession>
    <name>U1MJ24_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01598</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="1">
        <location>
            <begin position="174"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="557" mass="62588" checksum="DD434285ECB31F79" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK52</accession>
    <name>U1MK52_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate uptake regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02087</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_02087"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="332" mass="36531" checksum="45C55A8773758496" modified="2013-11-13" version="1">METRKVQVTGGSTYTVSLPKGWATENKVTAGSVVEFHSEEDLLLVTPHTEDGRVEGTMDVTGLTTEHELTRAVMTMYVSGFDVITLESDPMTADQRRAVRDASQRLVGLEVIEEQPNGIVLQDLLDSSELSIQNAVTRMRLVSLTMFEDAVEALVTGDETLADDVIERDNDVDRLWYLTSRVLRQVLRNPTAADEIGFARETCFDLQSTARQLERIADHATKIAELSLETETVPEDAVKQLQTLRREAAAVPETAMDAVLTDDPDEAVELAATARAQIDDVNERARALNAEIREYDPQLAQTLGLVTDSLSRTADYGGNIAENALQMAAPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MK95</accession>
    <name>U1MK95_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_02157</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89984">
        <property type="protein sequence ID" value="ERG89984"/>
        <property type="gene ID" value="J07HX5_02157"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2459731_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="88" mass="9308" checksum="68AA640FD88D1128" modified="2013-11-13" version="1" fragment="single">EAAFAATESVPPGLTLVILAITLVSVVDAYWMAGRLNSGDQPTPPSSSSETDATTTESSTQECPNCGREIDGELTFCHWCTTRVDENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVA9</accession>
    <name>U1MVA9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoenolpyruvate synthase/pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00024</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87883">
        <property type="protein sequence ID" value="ERG87883"/>
        <property type="gene ID" value="J07HX5_00024"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3432222_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="16" mass="1985" checksum="8C63DBB6DBB03E40" modified="2013-11-13" version="1" fragment="single">KLHSRQRCRGRLRSEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVB7</accession>
    <name>U1MVB7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative nickel insertion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00186</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88045">
        <property type="protein sequence ID" value="ERG88045"/>
        <property type="gene ID" value="J07HX5_00186"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028523_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="445" mass="46714" checksum="2331333190B3FF86" modified="2013-11-13" version="1">MRTLAFDGRMGASGDMLLGALLAAGADWSALTPAIEGLPVEYESDTTTRAAITATTVDVTPGDVSNAQTSESDTAETASRNKGQAHADSHSHDYGHGQNSADSHEHAHAEGDVTHRSHEAVKEIIRELELPTMVRQQAEQIVDVLAESEAAVHGTDTTAVRFHEVGADDAIADIVGVCLLVDDLSPERIVTTPLAAGGGETEMTHGTYPVPAPAVVELAAQADWELHGGPVEAELLTPTGAAILTVLADGVDTLPSLAVEATGYGAGLRTFPDRPNVLRATVGERAGDLRREPIAVLETNLDDAAPELLGGLQESLIDAGAVDVSVLPATMKKARPGHLVKVVAPRAKTRQVATRLAKETGTLGVRATRADHRFVADRSVETVELTIDDKSHAVAVKIARTRDGEVFDVSAEFDDVQAVAAETGLATKTILDRAEQQANQSVVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVU3</accession>
    <name>U1MVU3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00235</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88093">
        <property type="protein sequence ID" value="ERG88093"/>
        <property type="gene ID" value="J07HX5_00235"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2613462_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8276" checksum="37CE76F6C07EFA1E" modified="2013-11-13" version="1">MINADNDDSSVPAEFILILVGLALSAGEFINLTESIGVGQAPLSTIGNFLIDTRVGIALFKLSQSTDKSPLSQILRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVX7</accession>
    <name>U1MVX7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Competence/damage-inducible protein CinA C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00418</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88275">
        <property type="protein sequence ID" value="ERG88275"/>
        <property type="gene ID" value="J07HX5_00418"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="2">
        <location>
            <begin position="15"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="19269" checksum="A3D36DE9C9D445B4" modified="2013-11-13" version="1">MASDQRTDTDTDSDSVVTQLAAALTTTGATVAVAESATGGLVGSLLTDVPGASEYFDRGHVTYSNDAKQAVLGVSREALEHGAVSAPVAREMAAGARDTAGTTWGLSTTGVAGPSGGTAQIPVGTVYIGLAYASPWGAPADEPVSAQRFETNGTRHECKRQFALTALSTLQTAVTERGAGSESVSSSGSGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVY6</accession>
    <name>U1MVY6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00286</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88143">
        <property type="protein sequence ID" value="ERG88143"/>
        <property type="gene ID" value="J07HX5_00286"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2504831_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="85" mass="9186" checksum="13F35AE0EBC68EC4" modified="2013-11-13" version="1">MPPLILDEPTVFLDDSHVSQLLELIDAMRELGVEQILVVSHDDELVAAADTLLQVRKDPTTNRSTVETAAPHQGLVVGQSGGRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWB3</accession>
    <name>U1MWB3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chorismate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00545</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88400">
        <property type="protein sequence ID" value="ERG88400"/>
        <property type="gene ID" value="J07HX5_00545"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131518_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="112" mass="12810" checksum="749543966FFC60FD" modified="2013-11-13" version="1" fragment="single">GNPVMTDEQRESPATVRSGSDPTEMNLDQLRQEIKEIDREIVELIARRTYVAETIAAVKADRDLPTTDEQQEQQVMDRAGANAEQFDVDANLVKAIFRLLIELNKVEQREQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWF6</accession>
    <name>U1MWF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00457</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88313">
        <property type="protein sequence ID" value="ERG88313"/>
        <property type="gene ID" value="J07HX5_00457"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034716_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="40"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="233"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="321" mass="34945" checksum="129408CBBF4437F7" modified="2013-11-13" version="1">MSVTDAAEQVDTIIEEVRSVVVADRAVLESVLAAVLARGHVLLEDVPGTGKTLLARSVATGLGLNFSRIQFTPDLMPSDITGSYVFEEGSGEFHFTPGPVFANIVLADEINRASAKTQAALLEAMEENQVTVDGETHSLPDPFVVIATQNPVEQEGTFELPEAQRDRFIIKTSLGYPDPAGTQELIARRADRDRPDPTVARVINRESVRELQRVPESVVMEQPLREYLGRICRETRADSRVEIGVSPRGVQRLFEVARAHAVLNARSYVVPDDFKRVAGPALAHRLVLNPEARIQGVCRQDVIDSVLAGVEVPAMEPPAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWW4</accession>
    <name>U1MWW4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein UspA related nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00786</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88640">
        <property type="protein sequence ID" value="ERG88640"/>
        <property type="gene ID" value="J07HX5_00786"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_16_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="141" mass="14986" checksum="B3D9523ACF3BA550" modified="2013-11-13" version="1">MRYIVATDDSAASDQAVAYASRHAVALNATLEIVHVLAPDTELIDGEIVMTGGDTAYEAGQQTVKRAQRLAREHASDTPPAVETALLTGRPADALTDHAKEIDADGLYLGHRGLDEKREQVVGSVAKSVLDKATVPVTIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXR9</accession>
    <name>U1MXR9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00949</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88803">
        <property type="protein sequence ID" value="ERG88803"/>
        <property type="gene ID" value="J07HX5_00949"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2091219_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="116" mass="12301" checksum="54C5E68BD3BCE17F" modified="2013-11-13" version="1">MNTIEQNMAVTSFDPDTTASINERSKNIAMGFGFTAPSGTGFSALISNTTCVRDGEHGPWMGEVDIGSAGKFGVSLNASCTTGRQTPKSGVRTRAADRDQGDKEYYVSFTAHCGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXS7</accession>
    <name>U1MXS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PhzC/PhzF related epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00959</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88813">
        <property type="protein sequence ID" value="ERG88813"/>
        <property type="gene ID" value="J07HX5_00959"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_968398_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="287" mass="29373" checksum="0A67BF3C90C30111" modified="2013-11-13" version="1">MNTVQLVQIDVFADEPLGGVPVAVVLDAELSERQCRRVGAELGVAGVVTHQAASRVVPVREHIGIEAAVATATALFQRDRIPPGEHSIETPSGKQSFELATDGAVSNVGPRHALEYPTGLIERTATALGLDPATLKDVGADLPPGIVEAAGGTLSVAVNFFQHLSGASAGPLLGELLESIGAKRLCLFTFDTPDRGADVHARVFTQNGTAVSASAAAAAACGAHLADAAVFDPGRTSVVIASGSAVDRPARLTTTLDAQPRLTGRGLTGIDGTLSLPPDDDDEILEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXV5</accession>
    <name>U1MXV5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HoxA-like transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01125</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88975">
        <property type="protein sequence ID" value="ERG88975"/>
        <property type="gene ID" value="J07HX5_01125"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114810_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013971">
        <property type="entry name" value="HalX_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08663">
        <property type="entry name" value="HalX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="15875" checksum="109EBB03A9B1B6A4" modified="2013-11-13" version="1">MPGISGDEVLETIRNRGISPRVAMVTAVDPDFDIIDMPFDDYVIKPVSRDDLIETVERLLTASDYEQKLQRYHSLAGKHATLLANKPQSELADNEEFQQLSDQMNQLQEKLDDQVTSFSDDDFKAAFRDLDAGLPGADQAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXW6</accession>
    <name>U1MXW6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01140</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88990">
        <property type="protein sequence ID" value="ERG88990"/>
        <property type="gene ID" value="J07HX5_01140"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1965468_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="14025" checksum="D3F981B16ACBEF36" modified="2013-11-13" version="1">MLTENALLACRNVLVPALAEVTSKHALDILFEHFETLENGYGVSVDPIGIVINRIEVDGEADRMIEWFEESFGDTMPLWRVRNRVTIKRALAHNASVFGHSEQTDMAARFSAIADHLGITSTSAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY03</accession>
    <name>U1MY03_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01029</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88883">
        <property type="protein sequence ID" value="ERG88883"/>
        <property type="gene ID" value="J07HX5_01029"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_211275_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043902">
        <property type="entry name" value="DUF5786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19099">
        <property type="entry name" value="DUF5786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5786" evidence="2">
        <location>
            <begin position="9"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="63" mass="7294" checksum="FD0D0EA85C47926D" modified="2013-11-13" version="1">MDTCQPMSLGAYDDDEHERRERKNSEVNVSFDDVREEYNGSVEFEGEGSTEALLEQYERITGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY32</accession>
    <name>U1MY32_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01227</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89075">
        <property type="protein sequence ID" value="ERG89075"/>
        <property type="gene ID" value="J07HX5_01227"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949142_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6240" checksum="8F24FF7FC101AA37" modified="2013-11-13" version="1">MPVDTQAVSELVAMFSGDVAGVVPLIFTELHAECHGVERKTRSSVMTGGGVSRTTWPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYJ3</accession>
    <name>U1MYJ3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">V-type ATP synthase subunit C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">V-ATPase subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpC</name>
        <name evidence="10" type="ORF">J07HX5_01245</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89093">
        <property type="protein sequence ID" value="ERG89093"/>
        <property type="gene ID" value="J07HX5_01245"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059311_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00314">
        <property type="entry name" value="ATP_synth_C_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_su_c/d_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014272">
        <property type="entry name" value="ATPase_V0-cplx_c_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_su_c/d_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_suC/d"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="SSF103486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02923">
        <property type="entry name" value="AhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="356" mass="39579" checksum="C3FD2DBD4285625F" modified="2013-11-13" version="1">MSQSQTSGSSNPEYVNARLRTRRSKLFDNDDYRKLVRMGTGEIARYMEESAYESAINRLGARHSGVDLIEYSLNRNLATQFNDLLGWAEGKLYDQIAAYLRTFDAWNAKTALRGVYSGEPADGIQTDYITAGEFGPTLLDELAAAESVEEVVELLGETIFGEGLDQAYQQFTENETLVALENAIDRAFYEHLLDGIDTTVQEGPAALYLEALQAEIDFRNVRNALRLSETGTNLDPAAYYISGGRLFSETQLRRLTGDMNALLEHLRESSYGDDLDAALDALAEADSLVQFEQALDAALLEYADQLAYRYPVSVCSALSYILAKEREVENIRAIARGREVGLAVEEIEQELVVTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYJ6</accession>
    <name>U1MYJ6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01250</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89098">
        <property type="protein sequence ID" value="ERG89098"/>
        <property type="gene ID" value="J07HX5_01250"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3261780_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="42" mass="4338" checksum="DEC754CE011D74A6" modified="2013-11-13" version="1" fragment="single">VVRSVAGFATLQLYALGLLVGACAVVVHRTRTDNKQPGGDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYK0</accession>
    <name>U1MYK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AN1-like Zinc finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01255</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89103">
        <property type="protein sequence ID" value="ERG89103"/>
        <property type="gene ID" value="J07HX5_01255"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1559418_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="SSF118310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="171" mass="18506" checksum="20A34322BF10F205" modified="2013-11-13" version="1">MVECDTCGTETTMPYECRHCNGTYCAEHRLPEAHDCPGLKQWEQQGPVFDSGFDDSVGNPGSNGIADRLGIDTGPGGTLAYFRGNMTYVFLGLMWVASPPARVEPILGESALNALFVFSPDNPLYVWTWVTSVFAHYRLGSCIFCLTVSWSTSSAGSLNGQSAGRALPHCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYN2</accession>
    <name>U1MYN2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01437</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89280">
        <property type="protein sequence ID" value="ERG89280"/>
        <property type="gene ID" value="J07HX5_01437"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1598957_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="166" mass="18117" checksum="B19FAE25EDC037FA" modified="2013-11-13" version="1">MTVLVARRENRVLTTSLRSAGPIVTSSISRMMPTSGTNTPSEWSLSSQTQMRTLRSDGDDWIGPERIEETTQEDTQWRVARTNQQTRRTNCGTARATAADKVGSIGPKQQSIQQITIQSGPKERNKSAALPKKVRLDPALVDLGNNMSEEPLGVNVASLSLLSVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYU6</accession>
    <name>U1MYU6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl12</name>
        <name evidence="6" type="ORF">J07HX5_01362</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89208">
        <property type="protein sequence ID" value="ERG89208"/>
        <property type="gene ID" value="J07HX5_01362"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114656_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05832">
        <property type="entry name" value="Ribosomal_L12p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_L12/P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022295">
        <property type="entry name" value="Ribosomal_L12_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03685">
        <property type="entry name" value="ribo_P1_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="11524" checksum="7BF93366D210C6A8" modified="2013-11-13" version="1">MEYVYAALTLNETDAEITEDSLTDVLDAAGVEVEDARVKALVAALEDVDIDEAVAEATAVPAGAGASAGGAGDAAVEEEEAEDDDEDAVEEEEAEDDDEDDDAAGEGLGELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYY3</accession>
    <name>U1MYY3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trk-type K+ transport system, membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01409</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89253">
        <property type="protein sequence ID" value="ERG89253"/>
        <property type="gene ID" value="J07HX5_01409"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030708_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
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</entry>
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</entry>
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                <person name="Narasingarao P."/>
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</entry>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
    <sequence length="132" mass="14241" checksum="6FCA9154FAC93082" modified="2013-11-13" version="1">MPVDCVPNPIGQDLVLVGPTLFLEIISNTGSDSVAGNLLAALAGKQNKRKIRILCSNGLQELKPVHLSHLVIRDDAVRRLVVELLQPLINTCGRPDGELFLTALKKRFRQVGEGGLVIDVDDGDLAVHNSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZR2</accession>
    <name>U1MZR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01872</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89700">
        <property type="protein sequence ID" value="ERG89700"/>
        <property type="gene ID" value="J07HX5_01872"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1718144_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="16195" checksum="8C892F52F795F4EE" modified="2013-11-13" version="1">MDTEASTADRCGYVWRQDTPEVPSKSCCFRQTVDGSNRCAWHAGRGGTETRVADLLRAARAPTVVREQTSPYSEIIDGAVASEPGLPGGAYERTALRGADLADAPLRGVNFAQADLSEAVLAGAYLKDATLAGATLTGADLSRPFRRVSHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZR6</accession>
    <name>U1MZR6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01877</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89705">
        <property type="protein sequence ID" value="ERG89705"/>
        <property type="gene ID" value="J07HX5_01877"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2165170_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="110" mass="11432" checksum="7F64248D14409485" modified="2013-11-13" version="1">MFVSGPAELAQTTAFVRVTAVTAVLLGINGAVVGALRGAGDTRWPFAATLIGQYAVALPVATVGLVTPFGVTGLYAALVCGAAVPAAIDYWRYQTDQWKAVSRSYRPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZS7</accession>
    <name>U1MZS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutaredoxin related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01729</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89563">
        <property type="protein sequence ID" value="ERG89563"/>
        <property type="gene ID" value="J07HX5_01729"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_8_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="81" mass="9082" checksum="1DA5226F7F845EEC" modified="2013-11-13" version="1">MTQLELYELPGCPYCAKVKNKLSELGLEYESHEVPRSHDERTEVEAVSGQTGVPVLIDNEHNVDGMPESDDIVAYLQETYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZV8</accession>
    <name>U1MZV8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein family (UPF0153)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01917</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89745">
        <property type="protein sequence ID" value="ERG89745"/>
        <property type="gene ID" value="J07HX5_01917"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1507333_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="178" mass="20044" checksum="D9E8F7D7CE79CA46" modified="2013-11-13" version="1">MSKPASRRDDDQQPRRVEVHPGKEVVVEFDPSLTFECVDSCTWCCHHGVLLYEEDLLELANHASLSDATTQIRGEDFVQTESKARDEDVGTNGQACYFLRDDGLCALQAEHGWKPTRCSVFPLGVRVEDGDIHVAVREAAEEHCEGLNVSERRVIDHLDAFLPALLWELDDPATRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZZ9</accession>
    <name>U1MZZ9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01808</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89638">
        <property type="protein sequence ID" value="ERG89638"/>
        <property type="gene ID" value="J07HX5_01808"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151709_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="95" mass="11411" checksum="AA778BFFE54B051B" modified="2013-11-13" version="1">MVRQMYDLTHFQRDLLYVIAGKNKPHGLAVKQELEDYYEGEIHHGRLYPNLDELVDKGLVEKGQRDRRTNFYTLTSRGSREIKARRKWEQQYIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1N017</accession>
    <name>U1N017_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01829</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89658">
        <property type="protein sequence ID" value="ERG89658"/>
        <property type="gene ID" value="J07HX5_01829"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3378198_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="34" mass="3669" checksum="8E57BC744F0AD199" modified="2013-11-13" version="1" fragment="single">MWFGADRVGESAVRAPVVVRQQNSAIGPDTLANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N022</accession>
    <name>U1N022_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01834</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89663">
        <property type="protein sequence ID" value="ERG89663"/>
        <property type="gene ID" value="J07HX5_01834"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3302612_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="39" mass="4018" checksum="71813312E1578E0A" modified="2013-11-13" version="1">MEEEAQAVNEGQTGTAIKDPDQIVEGAGSEVSPDGESQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0D9</accession>
    <name>U1N0D9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02078</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89905">
        <property type="protein sequence ID" value="ERG89905"/>
        <property type="gene ID" value="J07HX5_02078"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2745702_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="71" mass="7671" checksum="DB0342D604EAF2A2" modified="2013-11-13" version="1" fragment="single">NNVETAVIAEDLDATVLEDRGLGYLGVSDEQIQTIAEENAEVSANVEHEQSDPDPAEHLTAPQDGDWLVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0P0</accession>
    <name>U1N0P0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02045</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89873">
        <property type="protein sequence ID" value="ERG89873"/>
        <property type="gene ID" value="J07HX5_02045"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2678742_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="7736" checksum="563A1EFC0C8D100C" modified="2013-11-13" version="1">MAGTVGGHAVTVVDVPGTLGGSEAWYNQVTTGTVAALDRATVLVGVGETALEGLPVEKKRPRRQQWRSPPKPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0P5</accession>
    <name>U1N0P5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="10" type="ORF">J07HX5_02050</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89878">
        <property type="protein sequence ID" value="ERG89878"/>
        <property type="gene ID" value="J07HX5_02050"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_3_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="8">
        <location>
            <begin position="15"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="198"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="9">
        <location>
            <begin position="264"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="579" mass="62862" checksum="938E55A81D58835D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1N0R8</accession>
    <name>U1N0R8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoglycolate phosphatase</fullName>
            <shortName evidence="1">PGP</shortName>
            <shortName evidence="1">PGPase</shortName>
            <ecNumber evidence="1">3.1.3.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02081</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dephosphorylation of 2-phosphoglycolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-phosphoglycolate + H2O = glycolate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="EC" id="3.1.3.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal SPP-like hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89908">
        <property type="protein sequence ID" value="ERG89908"/>
        <property type="gene ID" value="J07HX5_02081"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01419">
        <property type="entry name" value="GPH_hydrolase_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
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        <property type="entry name" value="PGPase"/>
    </dbReference>
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        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="242" mass="24840" checksum="31304412000E59C4" modified="2013-11-13" version="1">MDVAAGKTLADRIPATAPPLAVDIDGTLTDDQRSLDPCVMPVLRAWPAPVVIATGKAMPYPVALCEFLGIETAVVAENGGVVAVEQTDTLHVAGAPEAADAVAKELVAAGQPPDWGSLDLVNRWRKTELAVPRTTPLAPLEGIAERHGLVVVDTGFAYHVKSPAVSKGDALETAMTELNVALETVVAIGDSANDVSAFEAVGRGIAVANADDHARAAADLITDASYAAGFLEAVATTIETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3C1</accession>
    <name>U1P3C1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00133</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87992">
        <property type="protein sequence ID" value="ERG87992"/>
        <property type="gene ID" value="J07HX5_00133"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2066224_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG87992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="118" mass="12108" checksum="56C9D6D5A3DD47A6" modified="2013-11-13" version="1" fragment="single">GRTRATQRCTDSTATAGAPKRRSGHSTTSGKRPPVVLILVVLLLPAAGTVLAEIVGVDGVLRATAAMPQAVTAVSEIAAGVRAHIANSGANLWIVAILVTFRLVALVVDCRTLSRTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1P443</accession>
    <name>U1P443_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Archaeal Lon protease</fullName>
            <ecNumber evidence="13">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP-dependent protease La homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">J07HX5_00420</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cell membrane</location>
            <topology evidence="2 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase S16 family. Archaeal LonB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="13"/>
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        <property type="protein sequence ID" value="ERG88277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00420"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_392630_0_0_2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004663">
        <property type="entry name" value="Lon_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00764">
        <property type="entry name" value="lon_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12 13" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 13" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="15">
        <location>
            <begin position="231"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="16">
        <location>
            <begin position="518"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ERG88277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="732" mass="79184" checksum="4A86E7B3F4FA0D8D" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4L0</accession>
    <name>U1P4L0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00592</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88447">
        <property type="protein sequence ID" value="ERG88447"/>
        <property type="gene ID" value="J07HX5_00592"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153623_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="12052" checksum="AEC224F04562AE95" modified="2013-11-13" version="1" fragment="single">MTAVDEWEQLLADAGELTPAAVDRIATIHGDRGVRAIEAVDERRIKKYNDFIIVVGYEDEYIVENDGCTCKDAEYNLDADDPKQLCWHAVAVRVARAIGAVDVTRCGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4S8</accession>
    <name>U1P4S8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00673</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88527">
        <property type="protein sequence ID" value="ERG88527"/>
        <property type="gene ID" value="J07HX5_00673"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_5_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13491" checksum="DD4BB03435E04396" modified="2013-11-13" version="1">MQFAHAGIATDDAAGLAAKYTALFDRPIVHEETIDGMAVVVLGLDGADLELLEPRDGGPIATYLDRKGPGIHHVAFATPDIGAALERAREQSIELVDDQPRPGARGHDVAFLHPDSTGGVLVEFVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P584</accession>
    <name>U1P584_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase sliding clamp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Proliferating cell nuclear antigen homolog</fullName>
            <shortName evidence="3">PCNA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pcn</name>
        <name evidence="8" type="ORF">J07HX5_00853</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PCNA family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88707">
        <property type="protein sequence ID" value="ERG88707"/>
        <property type="gene ID" value="J07HX5_00853"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043978_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PTHR11352:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCNA_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PCNA_C" evidence="7">
        <location>
            <begin position="187"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="247" mass="26757" checksum="687D1DCEF6E38C4B" modified="2013-11-13" version="1">MFNAIVRADTLQATLDSVGVLVDECKIHLDENGFDIRAVDPANVGMVDMSLAASAFESYEADGGLIGVDLVRLQDIAGMASGDQLVQLALNEETRKLQISIDGLEYTLALIDPESIREEPDLPELDLPAEIVIEGRDIDRAVTAADMVSDHIELGVEEDTPNFYVKAQGDTDDVHLELGEKDLINVVAGPAASLFSLDYLDDMNKAIPKDAEVTLELGEEFPVKLHFEVAAAEGTVTYMLAPRIQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5J8</accession>
    <name>U1P5J8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00953</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88807">
        <property type="protein sequence ID" value="ERG88807"/>
        <property type="gene ID" value="J07HX5_00953"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968316_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="6519" checksum="A05D46503DDADA91" modified="2013-11-13" version="1">MLRLEFVTGRELHATEWGGVGEYDYPDECRVSQKSSRLVCGGYSVDSPSTFDNAYILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5K3</accession>
    <name>U1P5K3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00958</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88812">
        <property type="protein sequence ID" value="ERG88812"/>
        <property type="gene ID" value="J07HX5_00958"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3415712_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="27" mass="3348" checksum="4345C0F667A4C193" modified="2013-11-13" version="1" fragment="single">MERFRSRLTTTMRSSKPNPFPFFQQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5S3</accession>
    <name>U1P5S3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01008</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88862">
        <property type="protein sequence ID" value="ERG88862"/>
        <property type="gene ID" value="J07HX5_01008"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074702_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="42"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="213" mass="22706" checksum="68F24897C5A38142" modified="2013-11-13" version="1">MPTKSGLTQRLGVVVGFSNPRAALEQYRTPPRLAAEIVHLADLQDDIAGQTVFDLGCGTGMLALGAALRGPNTIVGIDLDRAPLATAVTNERRIGSTTSISWLHADATQPPITPVGSSTVVMNPPFGAQAGNEHADRAFLNTAAVLSSVSYSVHNADSKAFVESFAADHGGHVTHAFRTEYRLPATYEFHTETARTIDVEVFRIVWSNKAEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P681</accession>
    <name>U1P681_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01214</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89062">
        <property type="protein sequence ID" value="ERG89062"/>
        <property type="gene ID" value="J07HX5_01214"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077325_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="342" mass="34185" checksum="351D3612FF3F4BAC" modified="2013-11-13" version="1">MTLASLSIPIVLAGLAGGAFGAVVGARQALALAGALIVVGELNGGSGSGGSLTGTPALEIEGLGGTLGVGPLFGPHVAFAGGVAAAAYLGRSQMFDTGFRYHQAKSIGKPLGSRPKLLAVGAAFGGGGAVLAQLIFAVGLPLDPVALTVVLSAVVHRVALGYPLVGPVRDGLLDMSPFERQERWEGDRGRKHGRRGRLIVEPWLPEHYAWDQVAALGAVVGAAAGYLARVSNSVFLAFGLTAASLVVLSAGRSSFPVTHHMALPAGIAAVAVDAGPAVAIVVAAGFGVVAGLVGEFGERALYAHGDTHFDPPMVAILITSLLLTGLAAAGVLEPGPIPYPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6H6</accession>
    <name>U1P6H6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01325</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89172">
        <property type="protein sequence ID" value="ERG89172"/>
        <property type="gene ID" value="J07HX5_01325"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1478864_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="182" mass="19111" checksum="F172424C08E245D9" modified="2013-11-13" version="1">MGGCQSYVRGEQTPPVPEADELLRLSAAFAVQPTEPAVTTAVTFDATASTPVPGNSVDEYEWTLGDGTTATGETVSHSYDDPGEYTVELMITSGDERGRRHKSLVVQPELTAALGVSVESPTTTDVVRFDAGETVPGDSIDQYKWTLGDGTTATGEPSHTATTTPASIQSSSPSRAVTTRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6S7</accession>
    <name>U1P6S7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01434</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89277">
        <property type="protein sequence ID" value="ERG89277"/>
        <property type="gene ID" value="J07HX5_01434"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3338304_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="37" mass="4226" checksum="806CE2B93B1E74C4" modified="2013-11-13" version="1">MVSSSKKLFGFRDLTNWSTLEPLSEAMMAKTRQATVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Y2</accession>
    <name>U1P6Y2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein UspA related nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00002</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87861">
        <property type="protein sequence ID" value="ERG87861"/>
        <property type="gene ID" value="J07HX5_00002"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101252_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="129"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="235" mass="25788" checksum="4DA3A54DE7D66A20" modified="2013-11-13" version="1">MSRVLVPFELPDAAALSQTLVDELASVEVVLLGHYNLPEQTPSRAASEQFGDDATAEMDEIAAQFQEAGADVTRRVVFGKDRDAAIEEVATEEGCVAELIPAETDNMDQILVPIPDADIDRLPEFVRLMYNDLTQEITLLHVADDDDAVERGTQRLAEARTQLVEAGFDPGLIDSTLLEGGDHDSEIKATAAEYDAVVMYEANSRLRDFMFGSLPDQIANETDDPVLVVQRDYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1P782</accession>
    <name>U1P782_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase_M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_00127</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87986">
        <property type="protein sequence ID" value="ERG87986"/>
        <property type="gene ID" value="J07HX5_00127"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1582843_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="95"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG87986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="168" mass="18492" checksum="2283F3805B56ED25" modified="2013-11-13" version="1">MAGRACPFYYISRYFFLMVGHNGLRLRMLLAGSILFGLYALLMGLVVLSFGATTPVLLAAVVLTLGFVVVQYKIGRWAALRSVSAEEMPKTGSYRDIHQAVERLTDDMGIEKPQLMVAEMGMPNAFAIGRKGDGTVVVSEEIVRLLTFXXXXXXXSACTAPMSLRSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7B0</accession>
    <name>U1P7B0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative archaeal flagellar protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01601</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89442">
        <property type="protein sequence ID" value="ERG89442"/>
        <property type="gene ID" value="J07HX5_01601"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145174_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002774">
        <property type="entry name" value="Flagellin_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42200">
        <property type="entry name" value="PTHR42200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="145" mass="15294" checksum="5C08B1DBED4E1743" modified="2013-11-13" version="1">MGLSVSGATAVILIGAVISFSTFYPAIMTTYTTHSDAIRDQSDRIVAQLNTDFAATNASYNATNESVTVTINNTGPEPLDISRLDVLVDGEYISSAARTATVVGRSSTRAVLANETLTIDVPATTEPERVKVISETGVARIVEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7B9</accession>
    <name>U1P7B9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01611</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89452">
        <property type="protein sequence ID" value="ERG89452"/>
        <property type="gene ID" value="J07HX5_01611"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052774_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="22"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="203"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="355" mass="38653" checksum="2CDAFE842C9B29A4" modified="2013-11-13" version="1">MKSTFARGETLNNRIRRLGTDESTPGLMLLTTPEAPVTDEMLSALSVPIFGGTFPAVIADGEKREQGGVVVQLETEPTITVVPELSDRPSEFDASLTNDKRPESGTAFVFADAYATEIDQFTRQLFRTYGTQYNYIGGGAGDLDNEHPSVYTNDGLIEDAAVIASIDRSSAVGVRHGWEKIAGPFQVTDADGPTIEALEHRPAFNVYQEVIDNHEGYTPTQNEFFDIAKQYPFAISRMDGEAIVRDPFTVDDSGAMTCFGDVPEGEFVHILTGDVDSLIAAASEAYTEAVSDDAGEILFFDCLSRVQYLEDEFNREMEAVGPKAGALTIGEIANDGRGHLDYYNKTAVVLSLVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7E1</accession>
    <name>U1P7E1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00197</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88056">
        <property type="protein sequence ID" value="ERG88056"/>
        <property type="gene ID" value="J07HX5_00197"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_10_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="93"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="213" mass="23125" checksum="96B95E86A0E24099" modified="2013-11-13" version="1">MLAARVYSLGVQIIQADAARRSHPHVIIPSTPIAGSYSHTVSVFDDGRARQYXXXXXXXXYATEYDLVAVEDLDIKPMLESSRNSQNTASAAWDTFTTMLEYKCKVESTHFVEVDPAGTTKECASCGVSADKPLWVREHSCPACGFEMDRDANAALNILSRGFEKLGVGHSEGTPVETALPMFTSSDRSDVVDTKRVIETGSPTLREAASAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7E2</accession>
    <name>U1P7E2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01638</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89477">
        <property type="protein sequence ID" value="ERG89477"/>
        <property type="gene ID" value="J07HX5_01638"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037945_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="224" mass="24164" checksum="F9A10164E0C49CBE" modified="2013-11-13" version="1">MLFLGVAIAFGVAGFGSFLRALSTIGAAATLAVGFALQDVIKNFVSGIFIFTDRPFRIGDWIEWDDNAGVVEDISLRVTRVRSFDNELLTVPNGELIDGTIKNPVDAPQLRMKVVFGVGYDDDIDAATEIIAEAADTHGEILDDPAPSVRVAELGDSSVGLQSRVWIEDPNRGKLTRIRSEYVQTVKERFDEAGIDMPYPNRTIGGGLSLETAEGVVEPTSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7H2</accession>
    <name>U1P7H2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative membrane protein (DUF2078)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01672</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89507">
        <property type="protein sequence ID" value="ERG89507"/>
        <property type="gene ID" value="J07HX5_01672"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137730_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89812">
        <property type="protein sequence ID" value="ERG89812"/>
        <property type="gene ID" value="J07HX5_01984"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197986_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="41" mass="4555" checksum="2B53723CF99E2271" modified="2013-11-13" version="1" fragment="single">MADLIVKAAVKEQLSEMNVASDLYTSLDDEVEELLEDAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8H4</accession>
    <name>U1P8H4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoesterase</fullName>
            <ecNumber evidence="1">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00566</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="1"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88421">
        <property type="protein sequence ID" value="ERG88421"/>
        <property type="gene ID" value="J07HX5_00566"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="219" mass="23816" checksum="5823A2FEF37811CE" modified="2013-11-13" version="1">MRFGLLSDIHGNKVAIEAVLADMPAVDAIVCAGDIVGYNPSHRECLERVRDQSITTIQGNHDRAVAEQGAFGFNSLAGIGVQHAQETLTDEQTTWLGQLPASRRVADGRVRLVHGHPADPDRYTYPREFSADLLGDESVLVLGHTHVQGHERFDDGIVVNPGSVGQPRDGDPRAAYAVVDLETLAVTEHRVSYDIERVQQAIADAGLPDRLGTRLEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8I6</accession>
    <name>U1P8I6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00581</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88436">
        <property type="protein sequence ID" value="ERG88436"/>
        <property type="gene ID" value="J07HX5_00581"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1964049_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="128" mass="14214" checksum="21D5B2BEE40E2561" modified="2013-11-13" version="1" fragment="single">YPFTTLGSESRELVLLPSLQPEQRRRRESDQPGFGLEDSAEGYTKDELIPDSNDGGCWQTIGRPMITHPTVEPMMAHNETLSNRSTILLAPDAPCPPAETQLLTNVISIGDIRSNVTELVVELRVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8K0</accession>
    <name>U1P8K0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UvrABC system protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_02029</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89857">
        <property type="protein sequence ID" value="ERG89857"/>
        <property type="gene ID" value="J07HX5_02029"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="158"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="346"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="424" mass="47383" checksum="9323C403800DF995" modified="2013-11-13" version="1" fragment="single">HFERQGDLVAAQRIEERTTFDLEMLQETGYCSGIENYSVHLSDRESGEPPHTLLDYFPEDFLTVVDESHQTLPQIRGQFEGDKSRKESLVGNGFRLPTAFDNRPLTFDEFEAKTDKTLYVSATPADYERDCSDQIIEQIVRPTHLVDPGVEVAPADGQVSDLIDRLQAMPDDERALVTTLTKRMAEDLTEYFDEAGLSVAYMHDETDTLERHELVRGLRLGEIDVLVGINLLREGLDIPEVSLVAILDADQEGFLRSETTLIQTMGRAARNVNGTVVLYADDPSTAMESAIAETNRRRQIQREYNERNGFEPKTIDKPVGEMNLPGSETDTGDVTSLDPDDAAEAKTAIDELEDRMDEAAENLEFELAADIRDRIHGLRQEFDLAGTTTAFRRPTPSSDSVAVDRCRVTVGDSDRSARPGAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8M7</accession>
    <name>U1P8M7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00631</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88486">
        <property type="protein sequence ID" value="ERG88486"/>
        <property type="gene ID" value="J07HX5_00631"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507745_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="449" mass="47780" checksum="0F09E5FB7A8178FE" modified="2013-11-13" version="1">MQSLSENRAQSALIGGVLLFGILVIAASSWQAVIVTHQNEAVEFTHSIELRQQLTELRSSLLSMTGRASVRSTPVTLGARYPPRTVFVNPPPAAGTLRTVGTRTPAVNITIENAAVADTSGSSIDDGAGDFWNGTPVAYNTGQITYQPDYTYYQRAPRIGYEHSLLTERFADGTELPLTSQTLVRDTRITLVTINGSLSETRTDTATVDLVPISTRPQAVELTNTTRPIRLVFASRLSTDTWNETLADQLVANGGHVLNGGVTPVCDGPGSFSVLSLTLEPNQRYQLVAARVNLGAGATDTKPAYLTNIDGNGTTLRPGTGQSLTVELRDAFNTPQSGVPIAATAADGIRLTDRQVETGADGRATIRCVADNTSVGAREVRFTVGETPPGAGYDGSTPTNLTVTVTITTDPLAPESTTDHEDDHGRGRSRSARLALFTQINTVALDQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8P7</accession>
    <name>U1P8P7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA-like transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00657</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88511">
        <property type="protein sequence ID" value="ERG88511"/>
        <property type="gene ID" value="J07HX5_00657"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2042858_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="36"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="121" mass="12741" checksum="7944096CF65C3B95" modified="2013-11-13" version="1" fragment="single">MLGLVSLQFGNRPILLIDRRVACMGSAYRNAGLFTVLSVLWGTAFVAIKAGLADLPPVLFASLRYDLAGVFLLAYAAAATDQLLPRSRADWAEVTVGAVLLIAAYNGLLFIGQQGVTSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8S0</accession>
    <name>U1P8S0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HELICc2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00682</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88536">
        <property type="protein sequence ID" value="ERG88536"/>
        <property type="gene ID" value="J07HX5_00682"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1716953_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HELICc2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="153" mass="16856" checksum="8560E3F45AC81985" modified="2013-11-13" version="1" fragment="single">FVADGDGVLFSSLWGTLGEGVSYDGEDARTVVVIGVPYPRLNDRTEAVQAAYDTVVDERDAGWQYAVEAPTIRKTRQALGRVVRSPDDFGARILLDSRYTDRAATATPEYAVRETFPPEERAELIDIQPEKLRFGLRNFYAGLGAYNGDPPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8T4</accession>
    <name>U1P8T4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02125</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89952">
        <property type="protein sequence ID" value="ERG89952"/>
        <property type="gene ID" value="J07HX5_02125"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2152519_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="111" mass="12187" checksum="F26C3D851C33B323" modified="2013-11-13" version="1">MRRGAKNVLSPPVVCPADTSGSARGLAGRAVVRQVVRVENTVDTDRTPAEILSCEAGPGFIWGNPTWFYCLTDHQPGPMRTVARSFDSIKRGRIGNAVWNVQTDERRESDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8U3</accession>
    <name>U1P8U3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_02135</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89962">
        <property type="protein sequence ID" value="ERG89962"/>
        <property type="gene ID" value="J07HX5_02135"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2216958_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="106" mass="12081" checksum="03E13CBAA9DFB2DD" modified="2013-11-13" version="1">MADSEFVQSNQPRDLWRHTRRVGRSVSSLSTDRVVQLSVPVLPRIEQSALSPRHTLPFGFRQVAIHRLSVVVGLFVDTTVCSSDFLDELVYLCRNELGNVVRVWCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P928</accession>
    <name>U1P928_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases (Flavoprotein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00787</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88641">
        <property type="protein sequence ID" value="ERG88641"/>
        <property type="gene ID" value="J07HX5_00787"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_810389_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIDA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="342" mass="36163" checksum="C991CF97EBFB74FC" modified="2013-11-13" version="1">MAHVSVVGGGVAGLAAAGHAAQSGHSVSLYESGSYADDQPRRGAWGEVVSDTTRLPTVDAATGVVREFEQIAVTVRDGSGLEQVAAMHGPALAVIDRGRVECAWRRALPAAVDVYTDHHVSSTEFRRLCRESALVVDASGPMPVSTAVTALTVPPSPAVKTLSTQSTGAFEPYFPVPAAVVGPQVKAFITTKSPQRATYGIGFECGRGPADGYAAFVGLCEAAGLPVPDRDTVHIGLEPTLSSRPPENCVTVIDEARVHLAGDAAGLVSGMNQFGICRAIDSAVAAVASWDQSVSYTDWLRRATRRRRLQTRLLKPLERRVGSRRFAAMLGRLPIGIRLSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9B6</accession>
    <name>U1P9B6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00877</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <position position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="33" mass="3139" checksum="44124FE7FCA5B8BB" modified="2013-11-13" version="1" fragment="single">MVVGDVTTGTDVLVIGGGPGGYVAAIRAGQLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9S2</accession>
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            <fullName evidence="2">N-acetyl-ornithine/N-acetyl-lysine deacetylase</fullName>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="312" mass="33375" checksum="E41E98EB7AF87E2C" modified="2013-11-13" version="1" fragment="single">DRLIEFFNTHDRAVYRDDAGNVRAPGDDSVLLTSHLDTVPGAIPVRIEDDTLWGRGSVDAKGALAALAVTAVRSGASFVGVVDEERRSRGARYLVDDRKAPAAVINGEPSGWDGVTLGYRGLLAGTYVTTSESGHTSRPSNNAIQDALDWWTRVESAVATDEWHPAFERVTPKPVAVDGGTTADGLSVEATMAVEFRIPPDRTASGVKELADGALETGTVNWQDAVDPVFESPRTPVARAFRAAIRAADGEPRMLRKTGTSDMNVYATAWDCPIVSYGPGDSALDHAPDERLPLSAYDRAVGALETAMERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1PA83</accession>
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        </submittedName>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="290"/>
            <end position="348"/>
        </location>
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        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="348" mass="37890" checksum="07FD99693719B19B" modified="2013-11-13" version="1">MSVNKKREEMARAREQFTEKQAEFTSYAARFDADTASKRDVSELRGEIDAVRQQMDEAAAGFSSYNEQFATEVDSFTETVAEQRDEMTSRRDLFTAYTNRFAADLAEKQDTGELQAAVDALTAEMKATTESFEAYADEFTAALVDKQDVSELVAATEQLQTEMTTTADAFDAAAAAFAADVSTKQDVSALTSAIGALAVEFDSFENEVTEYTTAFAADLETFAGEVMATREAFAAAAADTESYRETVFSNDVQELVDATTSFEAEMANLTAEFTETAQAFDGFTTAFIGTAETDGDTGSDEPAADARTEDNAKTENTEETDDTDETVTCRVCDQQYKQSPSHTSRPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAB1</accession>
    <name>U1PAB1_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
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        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">J07HX5_01192</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
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            <taxon>Halobacteriales</taxon>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
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            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
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        </reaction>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89041">
        <property type="protein sequence ID" value="ERG89041"/>
        <property type="gene ID" value="J07HX5_01192"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="424"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="424" mass="48521" checksum="A0FB3FF7A8606E59" modified="2013-11-13" version="1" fragment="single">AATATVLSLTANCRISGNRDSSHAMNNGTKPLIKWPGGKSAEFGRISDFLPPDAAYDRYIEPFLGGGAVFWRLRPTVAVLNDISAELMDFYRFVGDKQGRDRHQFEQALYGYVEHWQLLDELFSEVEDELLSAYTAYSSDAVSEHAFKQQIEQTLTDDTGLFAAFDEEFCVDRPALVHTTVERLQSKLVRTSDKIDQENEFPEADVLKNVEAGLKGGFYTHFRSVLNKAKLGSIELSRAREVANYFFIREFCYGSMFRYNASGEFNIPYGGIAYNDKDIEKKVDRIFSEQVKRTLGSADVRLHAEDFERLLDSCGPTENDFVFLDPPYDTDFSGYNNDSFTKTDHRRLADWLHTTPAQFVLVIKNTELIQSLYVEKERFQVESFQKQYAYNVRDRNEQSAEHLIVHSGTKKQTQLTDYGRQAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBD0</accession>
    <name>U1PBD0_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01524</name>
    </gene>
    <organism evidence="2">
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        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89366">
        <property type="protein sequence ID" value="ERG89366"/>
        <property type="gene ID" value="J07HX5_01524"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2228630_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="105" mass="11636" checksum="7F63670C5A5A8BF5" modified="2013-11-13" version="1" fragment="single">SPSRCRLITRALARRQSKTIMTRHTTETPTSTQETGRRQQLCRHPVVRWVWTTIQRVGFWVAVGLPVVYLPLLATGLKTPADGAVFGALLVANVVGLILGHEHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBS7</accession>
    <name>U1PBS7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase (Related to aryl-alcohol dehydrogenase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01696</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89531">
        <property type="protein sequence ID" value="ERG89531"/>
        <property type="gene ID" value="J07HX5_01696"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="278" mass="30168" checksum="929F11AE3D6AEB37" modified="2013-11-13" version="1">MPPATFQIGDRTINRMGFGAMRITGPGVIGPPEDEATARDLVRRALELGVDFIDTADAYGPGVSERLLGATDAPDRAVVASKAGLLRTPDGEWLPHGDPEYIKNQVLASRDRLGVETIDLYQLHRPDPETPLEETVHAFAELRDRGLIEHVGLSNVDVDQLERAREVVEIATVQNRYNVAHRADERVLAACEAHEIGFMPWYPLAAGEFGAASEPLAEIATNHDATVYQVALAWLLHHSEVLLPIPGTSSHAHLADNVAAAAIELTDDEYARLEAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBT3</accession>
    <name>U1PBT3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01702</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89536">
        <property type="protein sequence ID" value="ERG89536"/>
        <property type="gene ID" value="J07HX5_01702"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949144_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6725" checksum="E114A912D779745D" modified="2013-11-13" version="1">MPDDADRVVRALIDVIAVEQQAPGMIRVITVSDDYIVDTRHERCTCFDMQYLSPGRRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC78</accession>
    <name>U1PC78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01868</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89696">
        <property type="protein sequence ID" value="ERG89696"/>
        <property type="gene ID" value="J07HX5_01868"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_975216_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="285" mass="28460" checksum="194BD6C1713B56F8" modified="2013-11-13" version="1">MSPTPPLPRTSAGTVTVVTVGILAAVAVQVDNVAVPMLLGAFGSLCLAAGLRFGTGAAVSARGAAWASLLVVPTGAAIAAAPAVAMASVGKAIFPVPDMSLVSISVLIIVGHVGVVLGATVAATGVCVSARGIPSAGSAQTLARIAALTGIGPLVLAAGVTISALLTTDQTLSNGPTLPGTLPAPRRLVFGPSPQTQALDLWSFLLLLAGALIAVQRVVRVAPPRELLKSSLLLCLGPFPPLLTAARRPTAVWRLPCGADSLSPLASCLWLSLPSSCSVRTSWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCE8</accession>
    <name>U1PCE8_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01943</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89771">
        <property type="protein sequence ID" value="ERG89771"/>
        <property type="gene ID" value="J07HX5_01943"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="33"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="416" mass="45607" checksum="8B5D1657E0FD16FA" modified="2013-11-13" version="1">MATTRSDHDHVDVDALRDDFPILDREFGGEQLVYLDNAATTQTPDRVIDAIAEYYRKTNANVHRGLHQLSQESSIAYEEAHDRLAAFIGAEGREEMVFTSGTTESENLVAYAWGLNELSPGDEVVMTEMEHHASLVTWQQIADRAGASVEYIRVTDEGHLDMDHAKELISPDTAMVSVVHVSNTLGTVNPVGELAELAHDNDAHIFVDGAQAVPNRPVDVQDIGADFYAFSGHKMVGPTGIGGLYGRQELLEEMDPFQYGGEMISRVSFDDATWNELPWKFEAGTPPIAQAVGLAEAADYLDEVGMENVERHEGALAQYALRELEQFDDIRVLGPSSGTTRGGLVAFDIESVHAHDVSEILNGVAVAVRAGHHCTQPLHDKFGATATARASFYLYNTREEIDQLITAVKQAKQLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCY2</accession>
    <name>U1PCY2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02124</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89951">
        <property type="protein sequence ID" value="ERG89951"/>
        <property type="gene ID" value="J07HX5_02124"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2433732_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="9116" checksum="A00A372541809434" modified="2013-11-13" version="1">MCKPMSGEKATVDDGDNGPNIGVVAGVAFTAITLLAAIAYTVMLNLVDWVAVGVLSYPVAGVAPFAVITGAILTIPIVVPTVLVTARFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFP7</accession>
    <name>U1MFP7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00115</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87974">
        <property type="protein sequence ID" value="ERG87974"/>
        <property type="gene ID" value="J07HX5_00115"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949140_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6706" checksum="97A1B0CC830837A5" modified="2013-11-13" version="1">MVGAVSLVTGEPIANQRIKRPVFYTITRRMSRGRTEDSVFGDDEGRCLSNHLTPRQFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFQ7</accession>
    <name>U1MFQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00130</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87989">
        <property type="protein sequence ID" value="ERG87989"/>
        <property type="gene ID" value="J07HX5_00130"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1485845_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="181" mass="20038" checksum="C1FEBA43295D745F" modified="2013-11-13" version="1">MAVTVGRLTANVSCGRVSACGGESDRKQRDLRAFHPVHRTVCQHPAAEAVCLSVASRVSHATVKRPAPGPCDRRMFLTTAQKGRETQTERAEKFDLLLGDEPPRLTLIEAMPTPKHILYAEQAQDHGVNAADTRYHSVIRCIGNGLAEFPTHTLNYQQLSCRTRSGWNRAVPNGLRKRSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MFR5</accession>
    <name>U1MFR5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar pyrophosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00140</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87999">
        <property type="protein sequence ID" value="ERG87999"/>
        <property type="gene ID" value="J07HX5_00140"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="40735" checksum="0DC6537B1E6F85D1" modified="2013-11-13" version="1">MRRNDRTTAVILAAGEGRRLAPLTNRRPKPMLPVVNKPLLEHVVEAVVGAGIDRIVLVVGYQRKRIQTYFGDGDEWGIDIEYAVQRTQLGTAHALEQAAPLVEGRFVALNGDRLLTSEIVDQIADSSDDTTVTMAVTRASDPSTYGVVSLDGTVVTSIVEKPGPEAQSRVINAGVYGFTQTIFDVIEKTDPGPDGEYRLTDAIGQLVDSRDRVRAVQYNGRWLDVSHPWDLLSVTGQLLDTAGKATLGQRGAGAEVSDAARLADTASVGTSVVVGRGTVVGENARIGANATVERSVVFPDATVEAGAVLRDCIVGANASVGANTTVPGGAATVTLAGDVYEGVRLGGVIGDNTTVGGGATLHPGTILGDSVKIAPGVSVSGTIDDETAVRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MG69</accession>
    <name>U1MG69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00342</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88199">
        <property type="protein sequence ID" value="ERG88199"/>
        <property type="gene ID" value="J07HX5_00342"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3400308_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="31" mass="3327" checksum="CD6ACEA90B154372" modified="2013-11-13" version="1" fragment="single">MGFCEYTMTTHGGESHRDSGSPPGHTHNHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGD1</accession>
    <name>U1MGD1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00412</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88269">
        <property type="protein sequence ID" value="ERG88269"/>
        <property type="gene ID" value="J07HX5_00412"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_6_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16952">
        <property type="entry name" value="Gln-synt_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="109"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG88269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="450" mass="48886" checksum="B7302F1125FD6050" modified="2013-11-13" version="1">MTDPADVLQRVDATDTELIRIVFVNNSGVPRGRVVDSETLPRILAEGANITQAMQSFNALDRLVADGQYGPAGEVRIVPDPATFTELPYADRTAVMLADLHDLDGDRWAAGPRSQLREYLDDIGADGYEPKLSFESEFYYTETTDDGELVPFDDTTCFSTDGMRSAHDLIRETIDALKTQGMGLSAYYPEYGPGQQELVVDHATGVAASDSQVLFTETVKAVAAANNVGATFRPHPFPELPGTGCHVHLSLWQDGTNVLHDPDADGRYPLSTRGRQFIGGLLEHAPALVALTAPTVESYERLAPGMWASAYTCWGYDNREAAVRVPSVETDRPAATTRVEFKPADNTTNPYLAQLGLLAAGMDGIDRELDPGEPLNRDPSTVDDETLAERGIERLPTSLDEAVAALEADDVLATALGDALHQSYLEVKQSEWAQSATEEGWDSAYLGRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MGX6</accession>
    <name>U1MGX6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_00644</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88499">
        <property type="protein sequence ID" value="ERG88499"/>
        <property type="gene ID" value="J07HX5_00644"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087840_4_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
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    </dbReference>
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        <property type="entry name" value="LeuE-type"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LysE"/>
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    </dbReference>
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    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="152" mass="16161" checksum="2F4EA1C52FD84E80" modified="2013-11-13" version="1">MFVTAFFHGLAISTGLIVAVGPQNVFVFQQGVIHPRLTSSLPTVLTASLADTFLILLGVLGVSAVVVELAWLRTTLLVGGIVFLTYVGWMLYSTPVTGLDATQENLLGVREQIGFTGTISLLNPHAILGELPRGQAPRLPTSTTRFASIASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH35</accession>
    <name>U1MH35_9EURY</name>
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        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar pyrophosphorylase</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">J07HX5_00735</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
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            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88589.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88589">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0009058">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="328" mass="35703" checksum="AC324ABE6402FAF6" modified="2013-11-13" version="1">MSAATLGYRMDAVVLAGGYATRLWPVTRHRPKMLLPVGSTTVVDRVLVALEADDRVDNVYVSTNERFADRFAAHLADTNFEKPQLSVEETVAEDEKFGVVGALAQLVDREALGTDDLLVVAGDNVLGFDLSRFLAFFEANETTALAAHDVGSREQASQYGLVELEGDRVVDFQEKPDDPPSTLVSIACYAFRAADIRFAEYLAGNNNPDEPGWFLQWLQARCSVQAFSFDEAWFDIGTPENYLAAVAWALEGDTRVAETATVDNATLGANVHLMDGATVRDATLERAVVFPDATVEDATLRNSLIDRDALVRGVDSTDALIGAHSRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MH97</accession>
    <name>U1MH97_9EURY</name>
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        <submittedName>
            <fullName evidence="3">Acyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00825</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88679">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000053694">
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="15758" checksum="01F7528FCBF0C824" modified="2013-11-13" version="1" fragment="single">EMTELLLPDSTNMLGRALGGTILRWMDVCGAIAAMRFANRPCVTASIDHVDFIAPIDVGEIVSITAYVFNTGETSIDVKVDVQAEDAMSGDKRAATASFLTYVAVDGDGTPVPVPALSCTTDEETQLQAEAVAEREHELERLVDRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHK9</accession>
    <name>U1MHK9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Double-stranded beta-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00955</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88809">
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        <property type="gene ID" value="J07HX5_00955"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1968790_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="15174" checksum="55ADAD25C453DEC5" modified="2013-11-13" version="1">MEELTVQSVAPAHEDARGTVYNLIDDTKVRNVLYVESDSGTNWGNHYHKSRTQYPYILQGGFTLYYQDLRHERSTPIKTAQMNVGDVIKIPPRVAHAFELNHPTEFIEIVNKPLGENGELYDQDTVEIDGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHL3</accession>
    <name>U1MHL3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00960</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88814">
        <property type="protein sequence ID" value="ERG88814"/>
        <property type="gene ID" value="J07HX5_00960"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2802056_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="67" mass="7526" checksum="34842A45E281F700" modified="2013-11-13" version="1">MPRLPRSPGLCVTDQTTTEPLEPLGAASWRPDCSTARIGTCRRKQHLDINSTVTATEIILRRFRHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHW3</accession>
    <name>U1MHW3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">J07HX5_01060</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88914">
        <property type="protein sequence ID" value="ERG88914"/>
        <property type="gene ID" value="J07HX5_01060"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3421814_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043825">
        <property type="entry name" value="DUF5802"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19118">
        <property type="entry name" value="DUF5802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="25" mass="3020" checksum="A2A676D67583FD6D" modified="2013-11-13" version="1" fragment="single">MFERFSSSYYLGRLYVQPSTDDRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI16</accession>
    <name>U1MI16_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01139</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88989">
        <property type="protein sequence ID" value="ERG88989"/>
        <property type="gene ID" value="J07HX5_01139"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1104653_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="252" mass="26490" checksum="4499732D0EF88330" modified="2013-11-13" version="1" fragment="single">MTESLSRRRALQLAAAALVPTAAGCFGTGDDRQPWHATWLPAGDGLSFTILELTVGADADAIPSVTPVVLPQGTPDEQQFEVNVSISSEIEDPLVAFPLTTGPRAIGLSAIALSIANLAELIDTPDAFASTPGRLLAVNGTVLITGSFDRGEIEKQLTDNTGPITASYERTGKRRGYDRYSPVEVPPRIERAPEGAPHIAVGEQAVLVGGDTSRLNRIVETAVGDRSPAVEANERLAWLIDQTSGGDLIVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI45</accession>
    <name>U1MI45_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01179</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89029">
        <property type="protein sequence ID" value="ERG89029"/>
        <property type="gene ID" value="J07HX5_01179"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_770748_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="359" mass="37685" checksum="86B893DB13CEF017" modified="2013-11-13" version="1">MGSTIALILLSNRLCWLGTPTCCCRSRLTQTIPACPLAFGCLPDIFCRVLAWLISCADRRQISSVRQQNTTLSRSRAWIENVAHSDASDAAGPAGDGRQLAGWDDEVSVPDELGFVGQKRQVRGQAVGAELVAAEAVPGDYPVEIDSSEALAIQFRVDRPPADGSADTDADAASTDSSATVDTTDDDGSDPDGSTSVPADPAPIVAYFSWPAGTDDRLSGLLELQGLDELAGLHGETALLALKEDYYLPAVPATPRGDGRALYAIYAGLVPHIVVALAGIFATGFNTLADSTAFLGVWAAATVLVLPVATYLDAAYLTTTTTWTGRPVVWAVAAAVPGLNLAALSLYLLRRRGVEPIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI78</accession>
    <name>U1MI78_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative eukaryotic snRNP-like RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01226</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89074">
        <property type="protein sequence ID" value="ERG89074"/>
        <property type="gene ID" value="J07HX5_01226"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003612_2_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT-R_1" evidence="3">
        <location>
            <begin position="506"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="714" mass="79072" checksum="A4D551BC2A68BC9F" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI85</accession>
    <name>U1MI85_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small nuclear ribonucleoprotein, LSM family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01236</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89084">
        <property type="protein sequence ID" value="ERG89084"/>
        <property type="gene ID" value="J07HX5_01236"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_11_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="LSM_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="64" mass="7033" checksum="DD27B90274544062" modified="2013-11-13" version="1">MDDAGARPLDVLEQTVGTTVRVELKDGAVHEGELVGYDQHMNLVLNIDEDTTIIRGDNVISVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIA8</accession>
    <name>U1MIA8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Disulfide bond formation protein DsbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01266</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DsbB family. BdbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89114">
        <property type="protein sequence ID" value="ERG89114"/>
        <property type="gene ID" value="J07HX5_01266"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128688_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003752">
        <property type="entry name" value="DiS_bond_form_DsbB/BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012187">
        <property type="entry name" value="Disulphide_bond_form_BdbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023380">
        <property type="entry name" value="DsbB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43469">
        <property type="entry name" value="PTHR43469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02600">
        <property type="entry name" value="DsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158442">
        <property type="entry name" value="SSF158442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="139" mass="14373" checksum="760CB3902283A8F2" modified="2013-11-13" version="1">MGHTDQTRLLQAATVVAVVGVVGSVLFESLEYTPCRLCYRQRWLLTAVGVVSVGCLRYRSGALYGLGVVTALTGATVAAYHTGLQLTAASQPGCVAGGCETVSYRVAGFVTIPMLSATAFGLTAVLLAAAVYDRVGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIJ3</accession>
    <name>U1MIJ3_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="2">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">truB</name>
        <name evidence="5" type="ORF">J07HX5_01384</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89229">
        <property type="protein sequence ID" value="ERG89229"/>
        <property type="gene ID" value="J07HX5_01384"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01081">
        <property type="entry name" value="TruB_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026326">
        <property type="entry name" value="TruB_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="PTHR23127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DKCLD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="316" mass="33262" checksum="11DC26A7A168EE87" modified="2013-11-13" version="1">MRAPPDDRSPAELLAFGVVNLDKPPGPSAHEMAGWLRDAAATAVTDADTSASSSPVPTIDRAAHTGTLDPKVTGSLPVLFGDATRLAQIFADSLKEYVAVLELHGPAPADFGAVVESFEGELYQKPPRKSAVRRRLRTRTVHTLDVLERDGRQALLRVRCGAGTYVRKLCHDIGLALGTGAHMGDLRRTAAGTFDETSLVTAETIVDALAFWASDDDPRRLREIVQPAERALIELARVVVAPSAAEQIAHGAPVYAPGVIRTEPAPAGGAESSLSPSSEELVACCTPDGAAVCLGRLVGDPTADTGTIVDLERVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIS5</accession>
    <name>U1MIS5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01487</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89329">
        <property type="protein sequence ID" value="ERG89329"/>
        <property type="gene ID" value="J07HX5_01487"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3020821_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="55" mass="6040" checksum="77A3A5FA559A6FFF" modified="2013-11-13" version="1">MSVTLMPAPWGLDVVCPFADSKTELKITLDSMTPRKVGCVDETVNYNGPLTVPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIT6</accession>
    <name>U1MIT6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metal-dependent membrane protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01497</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89339">
        <property type="protein sequence ID" value="ERG89339"/>
        <property type="gene ID" value="J07HX5_01497"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073769_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="278" mass="28898" checksum="8FB97603350F8C09" modified="2013-11-13" version="1">MTGSDRTAQPTLDPEPSGPINGGQSTTRTLLAAAGIGVLGIVLLQIAVSVVALTGEVAGFSIIPEEGKEIDLFPRTVLNGLGQIIAFGGLAAGYLRWRGNTLQRARARLGIRRPSVRELGVGAAGLVGMFLLLAGVGTIVSLFTTPAQNTATEGLSDNPQVIPGMVVVMLLIVGPFEELLYRGIVQTRLRERFSVGASVLVASLVFAVIHAGALQGTPLQAVATILILFTVSLVLGYLYEYTGNLVIPALIHGLYNSVQLAGTYAQGTGILTAVLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ38</accession>
    <name>U1MJ38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01618</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89459">
        <property type="protein sequence ID" value="ERG89459"/>
        <property type="gene ID" value="J07HX5_01618"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2445698_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="oligo_HPY" evidence="5">
        <location>
            <begin position="2"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="89" mass="9233" checksum="C96088D9C7F27FD1" modified="2013-11-13" version="1" fragment="single">ADPAHPYTTALLESIPGRTPPDEQLPTINGEVPTPNGPAEACRFAPRCPLAVEQCRAEAPDTVFVDTSTGHSAACIFAGETDTDGGKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ64</accession>
    <name>U1MJ64_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01658</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89494">
        <property type="protein sequence ID" value="ERG89494"/>
        <property type="gene ID" value="J07HX5_01658"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2313686_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="99" mass="10363" checksum="588FC70F60B7B5A5" modified="2013-11-13" version="1">MIVPVDSHGVVGDVLDPRLQVNGVSMDPTDGSPVVTGHGGRGRYASAGSSILDGFGGLSRVSVSRRSPEPEVENYPVLSHARQPIGYYFPTTVLGLWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJF4</accession>
    <name>U1MJF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histones H3 and H4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01778</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal histone HMF family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89609">
        <property type="protein sequence ID" value="ERG89609"/>
        <property type="gene ID" value="J07HX5_01778"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1801751_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBFD_NFYB_HMF" evidence="5">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBFD_NFYB_HMF" evidence="5">
        <location>
            <begin position="76"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="16078" checksum="2D6A731858411EC5" modified="2013-11-13" version="1">MSVELPFAPVDTIIRRNADELRVSSGAAEELARQIQQRGARLAASAADRAVEDGRKTLMLDDFSIETPPERSSLVLPVAPVDRVARLELNNRYRVSMDARIALAALLEQFADDVATAAAFLARHAGRRTVKAEDIEGYFQLAPQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJY9</accession>
    <name>U1MJY9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01996</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89824">
        <property type="protein sequence ID" value="ERG89824"/>
        <property type="gene ID" value="J07HX5_01996"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2163531_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019516">
        <property type="term" value="P:lactate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004452">
        <property type="entry name" value="4Fe-4S-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47153">
        <property type="entry name" value="PTHR47153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="111" mass="11947" checksum="899A817200603232" modified="2013-11-13" version="1" fragment="single">MSPPDNGAESHATRQERATELRQLIETEGKTIGTNTRRANRDADEACRQFPDHEATRSAARAVKEDAIERLPALIGQLEAAVADNGGELHLAESAEDATRIVEAILTETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV69</accession>
    <name>U1MV69_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00126</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87985">
        <property type="protein sequence ID" value="ERG87985"/>
        <property type="gene ID" value="J07HX5_00126"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949141_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="59" mass="6569" checksum="A42092591FB2E3C2" modified="2013-11-13" version="1">MSTGKGPLTPSVGVDTTRRTATDWKGWFVKIEHVTARIGETWGRCKQXXXXXXXQTLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVR2</accession>
    <name>U1MVR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00348</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88205">
        <property type="protein sequence ID" value="ERG88205"/>
        <property type="gene ID" value="J07HX5_00348"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059964_4_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="1">
        <location>
            <begin position="28"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="27682" checksum="B337BBBFA9006932" modified="2013-11-13" version="1">MTDQPTNDIAAAFENDAVVTGVLDDAYSPRLIELYGDLGLDFVWLDLEHGGPSPLDGDRISNLLRAAERTDIEPLIRVPTTDPTVVRKTLDLGARNVFLPRVTGPDEVRAAVRAGRFEYDDGPGDRGLSAPRASRYGLVDEYPETEDCEVLIGVTIETEAAVETIDEILAVPELGFVFLGPYDLSVAMGHPGEVDHPDVQAAVDRVRSAARDAAVPIGGLSFGPEDRAQKIDAGYRLLNLGSTTGALQAAAADWLDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVR4</accession>
    <name>U1MVR4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5912 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00204</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88063">
        <property type="protein sequence ID" value="ERG88063"/>
        <property type="gene ID" value="J07HX5_00204"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629557_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045586">
        <property type="entry name" value="DacZ_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19294">
        <property type="entry name" value="DUF5912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5912" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="8393" checksum="B6E4DB05C4C2B45E" modified="2013-11-13" version="1">MTGLGELLTQLDDDVEAVVVLTRDESSLKTLREDDRPVVLVAADDGTADHFVELPLEFASLKTXXXXXXXSTLATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVW1</accession>
    <name>U1MVW1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00398</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88255">
        <property type="protein sequence ID" value="ERG88255"/>
        <property type="gene ID" value="J07HX5_00398"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1727173_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="151" mass="17104" checksum="27AEB424DC0CC31A" modified="2013-11-13" version="1">MLSLLIYRSGYRILFVMMCHIIACMTSAQESDDMFDQFLADRGHDVETPRRAGTRATIETSVQTVADSTTRVQQRVRSVAGHRSVRVHRTTAALRAPRATAPRLSRRLLVTHGHGQLLLRSGLLALRETRCHHGRRRPAQAPRRRQSRDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MW61</accession>
    <name>U1MW61_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00494</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88350">
        <property type="protein sequence ID" value="ERG88350"/>
        <property type="gene ID" value="J07HX5_00494"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1159022_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="SSF57667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="222" mass="24444" checksum="BA50D4B76088324E" modified="2013-11-13" version="1" fragment="single">MATDPFKLAARILGIDAARLRQVASEDADDPDLSALSELFGTDLTALDELQDADPEESDWNITFGGDINQVTDPQSSSRRSRRGIGVRPGRRSRRSSSSQNASSSQNKWGCPACDRTFLSHQALQQHYEANPDHADTTVDAQTPEEEVDENQTGSEWIAFDDRVETFILLPEGATKDNLTVTYQSDEDLVEIGGATETTVDTSDITVSTEDEVSWRVTGRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWA6</accession>
    <name>U1MWA6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="4">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dtdA</name>
        <name evidence="5" type="ORF">J07HX5_00535</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DtdA deacylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88390">
        <property type="protein sequence ID" value="ERG88390"/>
        <property type="gene ID" value="J07HX5_00535"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_610619_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00562">
        <property type="entry name" value="Deacylase_DtdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018033">
        <property type="entry name" value="Deacylase_DtdA_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007508">
        <property type="entry name" value="DtdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34667">
        <property type="entry name" value="PTHR34667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04414">
        <property type="entry name" value="tRNA_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="467" mass="48783" checksum="EC6DD18CA7A29C37" modified="2013-11-13" version="1">MLGIVVSTADEASVAIGDQLRAVADWTAHADGHYRTDGAELVVVDQLHIELETPATLFSTPPALVAFASRHSGETGQLLTAHHTGNIGPAEYGGDPNTLARAAPAAHASALAALDEHAPAEYDVGAECTHHGPSTVGAPSLFVEVGSGPDQWTADAPARAVARAILSLRGVAADRQAAAQRRTVVGFGGGHYVPRLERVIRETDWAVGHVAADWALAAVADEALPRVVEAAFTQSQAAHAVVEGERPAVRRAIDRLGYRVVGETFLRETTDVSPELVAIAESRIGSVAAGLRFGAKAATADDLGTVCRLPSDLLETTRGIDRERTIDVVAAHAIAFDTDQGGSRPTGLIALPDVATSRSETTAEQPLDGAASADANPVVYDQLITGLLAVLQERYDSVDRDPRTATATTTAFDPAKARTLGVPEGPAFGRLADGEAVEVNGDRIPPGAVHERRERQFSLVVEPAETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWB1</accession>
    <name>U1MWB1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NurA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00540</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88395">
        <property type="protein sequence ID" value="ERG88395"/>
        <property type="gene ID" value="J07HX5_00540"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145185_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018977">
        <property type="entry name" value="NurA_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09376">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NurA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="242" mass="27731" checksum="95EB393B3CF940F4" modified="2013-11-13" version="1">MLDGPVYPTGLLSWVDRDPALRRLIVEETEFTGVVENYRRLVERFVERSVPLIGFVKNTTTKAITQLLRQKTGAPWVDDAAFFRRVLERQEGGDRQTGELTFTNWFRSQAGSDGLLVDGEVSERSLRVAGTLEPTAYELTFFMIYDPRDDLLYRIEAPHAFTRDPAVRDRLRRYALCAVAAEGGPPLAIEKADELARISRDGKQALRRRIERVFGTERRTEYNDKRWGDQRSGPQRTGHSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWI7</accession>
    <name>U1MWI7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Geranylgeranyl reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00487</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88343">
        <property type="protein sequence ID" value="ERG88343"/>
        <property type="gene ID" value="J07HX5_00487"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011777">
        <property type="entry name" value="Geranylgeranyl_Rdtase_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02032">
        <property type="entry name" value="GG-red-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="464" mass="50399" checksum="1A5FE30929A0AEE5" modified="2013-11-13" version="1">MATTQSGSGARRQTTWDVVIVGAGTSGSYAAATLADAGYDVVILERKTEAEAGHIACGDALKGASSFPDAIPRSQIKPSITNTDVDHGQFEIPQLGEVLDIPVPGELAVIDRLEFGRRLIDGAEQAGATVHYETVVQDVRQSERVEGVTTTHNSRTLNYDADLVIDAAGAMSLLQDKVDFAETTFDTNVTYSQFCSAYREVIHVDEPVDWSDALVFKATDRAAGYLWYFPRTPTEINVGLGFQMTEKPMQLVDDLRQDIQARPEFKNATVDDKLGAALPTRRPYDSAVAPGYVAVGDAAGHVNPTTGGGIAGAAYAGTYAGQAAVAALSSDGPTEAAMWEYNKRVMERFGARYAALDVYNIFVTASEVDELMGLLAALPVSKLSEALYSGSANVGWLLKAKLLLQTRGHWDTIYNLYQTKTLADELLAHYESYPDHPDQLDQWQTERDAIMDRVYEETGADPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWK5</accession>
    <name>U1MWK5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permeases of the drug/metabolite transporter (DMT) superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00666</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88520">
        <property type="protein sequence ID" value="ERG88520"/>
        <property type="gene ID" value="J07HX5_00666"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_5_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="157"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="309" mass="31751" checksum="BAD5D01E138D3D75" modified="2013-11-13" version="1">MGSAYRNAGLFTVLSVLWGTAFVAIKAGLADLPPVLFASLRYDLAGVFLLAYAAAATDQLLPRSRADWAEVIVGAVLLIAAYNGLLFIGQQGVTSAVAAILIATAPVLTTGFSRALLPQEGLAPLGVLGIALGFAGVGLVALPGESLTIDSLAAPGLIVLAAVSVALGSVLLERVNSAMPTESAIAWSFLAGAGLLHLASMATPTESLAEATASPDAIAALLYLAVFASVIGYVIYFRLLDRLGPVEINLVSYAVPVSAAAAGWAVRNEPIDAPAVAGFLVILTGFVLIKRRALADRIALVRQYRQTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWR2</accession>
    <name>U1MWR2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00736</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88590">
        <property type="protein sequence ID" value="ERG88590"/>
        <property type="gene ID" value="J07HX5_00736"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2611368_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="79" mass="8849" checksum="67489B091F2507C0" modified="2013-11-13" version="1" fragment="single">MGRIRHSIKLFLANCTSRSFCAATPGFLWRPGWDNDHGTVLPGTVRDAALNVSERYSDNRLLVHLLQSHIIFIGETAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MWW5</accession>
    <name>U1MWW5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00613</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88468">
        <property type="protein sequence ID" value="ERG88468"/>
        <property type="gene ID" value="J07HX5_00613"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1412320_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="19905" checksum="50451F51BFCB9BC7" modified="2013-11-13" version="1">MPTNHARLLIAALTVVALVGAVGLIGLGPAGADGATTDTAPLAPADTQLERSAGQTIAIDATGTASAAPDQATVRITVSETGNQTNVVRDQLTAGSTALESTLAELSVEYQTIRYEIEEPPRHVDRELPPVAGTHTYEVVVEDTDQIGAVVDAGADTGAEVTXXXXXXXGRSAVAQFKRRFESPPELPSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX32</accession>
    <name>U1MX32_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiamine thiazole synthase</fullName>
            <ecNumber evidence="4">2.4.2.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">thi4</name>
        <name evidence="6" type="ORF">J07HX5_00851</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycine + hydrogen sulfide + NAD(+) = ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:55704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:139151"/>
            <dbReference type="EC" id="2.4.2.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the THI4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.59" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88705">
        <property type="protein sequence ID" value="ERG88705"/>
        <property type="gene ID" value="J07HX5_00851"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053727_2_0_2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00304">
        <property type="entry name" value="Thi4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002922">
        <property type="entry name" value="Thi4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022828">
        <property type="entry name" value="Thi4_prok"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00292">
        <property type="entry name" value="TIGR00292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="65"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>glycine</name>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG88705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="310" mass="32761" checksum="0A07C57EEEC730C6" modified="2013-11-13" version="1">MCADQEFDGFADVSEADVTQEITKNWSDEFLEFSNTEVIIVGGGPSGLTAAKELATRGVEVMIVEKNNYLGGGFWLGGFLMNKVTVRDPAQSVLRELGIPFEKTDTDGLFLADGPQACSRLINAACNAGAKVQNMTEFTDVVVREDHRVGGIVMNWTPVHALPREITCVDPVAVESDLVIDATGHDAVVVSKLDERDVLTAPGIEHAKQNATGMDQTGDDSYGAPGHDSPGHDSMWVGESEDRVVEETGVVHDGLIASGMATATTYGLPRMGPTFGAMLVSGKRAAQAAIDELGVDVDAVPVTPTAPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX71</accession>
    <name>U1MX71_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine cleavage system protein P (Pyridoxal-binding), C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00729</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88583">
        <property type="protein sequence ID" value="ERG88583"/>
        <property type="gene ID" value="J07HX5_00729"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080866_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="144"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="272" mass="29401" checksum="8CA04CDB93757734" modified="2013-11-13" version="1" fragment="single">MTAHEQAQWADNEDGYEPLLAEKRTTERSVDVDLPETLTRDSLTLPDLSEPELARHYTRLSQMTYGIESGPFPLGSCTMKYNPSFLEDVTALDAASVHPDRPEDQRQGTLAVMHDLAEQLAAIGGMDAVSLQPPAGAAGEFTGALVARAHHEHNGEDRSEVIVPDSAHGTNFASAAMAGFEIVELPSGEDGRVDLDALEAAVSEETAALMLTNPNTLGLFEREIETIADRVHDVGGLLYYDGANLNALLGRARPGDMGFDIMHYNVHKTFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1MX93</accession>
    <name>U1MX93_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00754</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88608">
        <property type="protein sequence ID" value="ERG88608"/>
        <property type="gene ID" value="J07HX5_00754"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="38"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="376"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="408"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="637" mass="70628" checksum="278511BD77B1B4C6" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXF5</accession>
    <name>U1MXF5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00824</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88678">
        <property type="protein sequence ID" value="ERG88678"/>
        <property type="gene ID" value="J07HX5_00824"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070251_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="296" mass="32395" checksum="D06C20709284CE57" modified="2013-11-13" version="1">MTDHPEAVPPADTGPSHRTGDDTDQTDTDVEPVEVLVGLAEDGEIDPWDIDIVAITDSFLGRLDSADLRASGRALFYASVLLRMKSEAIMQPDTDEEGQNQDHNQPPGQAPGSFTTAPLASGPGDPGQDPFAGLENEIDRRLERKRARGTPQTLDELVRELREAERGSWWKRSREYDMSESEHRGGPQTLDYRSSAAIAADEDPTISQVTANTHGEDVDEIVDEVRAAITDQYDRGRAELLFREIATVGGSRVQTFLGVLFLAHRGHVRLRQDELFGDLWIQDPAGPAATDGAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXK0</accession>
    <name>U1MXK0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00879</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88733">
        <property type="protein sequence ID" value="ERG88733"/>
        <property type="gene ID" value="J07HX5_00879"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="10"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="331" mass="36041" checksum="71E198EF6161EE3B" modified="2013-11-13" version="1">MSQTTQTQSLTLVQAVRDGLYGELNRDEDVIVMGEDVGKNGGVFRATQGLLEEFGGDRVIDTPLAESGIVGTAIGMAAYGLRPVAEIQFLGFMYPAFDQIVSHAARLRNRSREAYTAPMVVRAPYGGGIKAPEHHSESTEAFFAHQPGLKVAIPSTPRDAKGLLAAAIRDPDPVIFLEPKLIYRAFREEVPEESYTVPLGEAAVRREGSDVSVFTWGAMARPTAEAAEELGEEGIDVEVVDLRTLSPLDEETIIESFKKTGRAVVVHEAPKSGGLAGEITATIQEEVLLYQEAPVARVTGFDIPFPLYALEEYYLPDTARIKDGIRETVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXP0</accession>
    <name>U1MXP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_00919</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88773">
        <property type="protein sequence ID" value="ERG88773"/>
        <property type="gene ID" value="J07HX5_00919"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012366_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012188">
        <property type="entry name" value="ME_PTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036684">
        <property type="entry name" value="ME_PTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="6">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="5">
        <location>
            <begin position="161"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG88773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="747" mass="79597" checksum="2BFF09418A29B0DC" modified="2013-11-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYF4</accession>
    <name>U1MYF4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01204</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89053">
        <property type="protein sequence ID" value="ERG89053"/>
        <property type="gene ID" value="J07HX5_01204"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3178442_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="46" mass="5436" checksum="9291B6ECA54F039F" modified="2013-11-13" version="1">MIDRVIERGEEALDRVASQTALDIAHRRLKRARWFSEWLGDEVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYL5</accession>
    <name>U1MYL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoate-protein ligase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01422</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89265">
        <property type="protein sequence ID" value="ERG89265"/>
        <property type="gene ID" value="J07HX5_01422"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022986_5_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="35"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="268" mass="29171" checksum="2CE805B1A644A0EC" modified="2013-11-13" version="1">MTNSATESWRLIVDSHRSGAMQMALEEVAAETAATGGPWTVRVYSWDSTLSLGYRQDIATVDRAYCDRNEIAVTRRPTGGGGIYHDAYGDISYSVVAPEDAFPSDLMTCYEQLCQPVLAGFEQMGVPAAFAERDHESIHEPSCYLRGINPAHDIVVGERKISGNAQYRQREAVIQHGSLSYALTPERHTGAFAADLSPATFTDRVTAIAAETTLDRTAAVETLASTLGEWADATDGGWTDAELDQARRLAENKYAADAWVADRTDPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYX4</accession>
    <name>U1MYX4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type polar amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">J07HX5_01398</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89243">
        <property type="protein sequence ID" value="ERG89243"/>
        <property type="gene ID" value="J07HX5_01398"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ERG89243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="245" mass="26332" checksum="632FBBBCD4487167" modified="2013-11-13" version="1">MTLVKFSNVSKTYGDEVVLNGISLTLDRGDVEVIIGPSGSGKSTLLRCVNRLAEVDSGAISLGGESVTAAETDVDALRRQVGMVFQDFNLFAHRTALGNVTLGLRRVRGFSKAEAERRAHEELEQVGLGAQADSYPAELSGGQKQRVGIARALAMDPELLLFDEPTSALDPELIGEVLGVMQALADDGMTMLCVTHELGFARSVADRLTFLEDSQIVERGDPDQLFTDPAVDRTAEFLSRLTGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYY8</accession>
    <name>U1MYY8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01415</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89258">
        <property type="protein sequence ID" value="ERG89258"/>
        <property type="gene ID" value="J07HX5_01415"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2519622_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="84" mass="8454" checksum="01A33E91D3F2C7A7" modified="2013-11-13" version="1">MVNARDLRDSDTHLEQALLSGFELECGGVDAVPLAGRLGAIVEDVAEVTAAGGTDGLGAAHTVARIDLCLDVAVVVGIKKTGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ08</accession>
    <name>U1MZ08_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Double-stranded beta-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01435</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89278">
        <property type="protein sequence ID" value="ERG89278"/>
        <property type="gene ID" value="J07HX5_01435"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149791_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="109" mass="11789" checksum="35E807719C7D9E9A" modified="2013-11-13" version="1">MNTDSVRDVADGLVESGAESTEALRTDNVSLEVMRFEPGDEDQMHAHGEDEIYIVQSGNAEINVENEVTAVSAGDIIHLEPGTDHRFQGFEDELIMTVAYAPAKGTHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ28</accession>
    <name>U1MZ28_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_01583</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89425">
        <property type="protein sequence ID" value="ERG89425"/>
        <property type="gene ID" value="J07HX5_01583"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025947_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="11">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="155"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG89425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="35638" checksum="E96AAE009499E52C" modified="2013-11-13" version="1" fragment="single">MGYQRGQCREXXXXXXXSWMLLLVVVLVLFSGLFADLTAAVAEFDALVLEAAVFFGGVVLAGRLLSAPFDLVTTFVVEEAYGFNEQSLGLWVRDWIVGTLIGAALVVPIGATVVWFVDTVALWPVAAWLLGVVVVVALQVLLPRVILPLFYEFEPLEEGALRAGIDEVFETAGYRTENVYEMNASSRSGHSNAFFSGLGPAKRVVLFDTLTESMDTEAIKSVLAHELAHWREGHIWKFIALSVVRLGLVFATLGALVESGIVYDAVPGAETPYVGLFVGLLVILPINRLSSPVENYFSLQYERDADAYAVEIVGGEPMARALAGWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ34</accession>
    <name>U1MZ34_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flpA</name>
        <name evidence="5" type="ORF">J07HX5_01461</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89303">
        <property type="protein sequence ID" value="ERG89303"/>
        <property type="gene ID" value="J07HX5_01461"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059055_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="209" mass="22327" checksum="99AD1F76CC885E3C" modified="2013-11-13" version="1">MRLPDGVQRRVIAGEERLATRGDPVYGEPTDGQWRAWDPSRSKLGRLLAAGVDTGLSGGDKMLYLGAASGTTVSHVADFAGPTYAVEFAPRPARELVGVAASRSNLFPLLKDARSPESYAHVVEPVAAVIQDVATRGQAAVALANRQFLAADGRLILTIKARSEDVTRDPAAVFEDTLATLRDGYTILATERLDPSHEDHLGVIARPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ38</accession>
    <name>U1MZ38_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ATPases involved in biogenesis of archaeal flagella</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01599</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89440">
        <property type="protein sequence ID" value="ERG89440"/>
        <property type="gene ID" value="J07HX5_01599"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1173343_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="241" mass="25798" checksum="F5943BD0983C2191" modified="2013-11-13" version="1">MSYQSLGLTDRDQVNKSLGGGIPTNSLVALTGDTAAGKSVWASRLAYGMVEEGTTVSIVSTELTAREYIDQMSSLEYNITTPLLTDQLKYFYVPSHTTQDAVSRLLTPTSVWDADVVIIDEFGGFLQTDTRLSELFARGDGAGAEATKQVLAGLTAAQSDGTVVLTTVNPNALPDRAVHEITTTADVHLSIEKTGLASPSPDSWSSVGFERCVVRLRIRSGSPSSRDAALLSNHERLHNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZB0</accession>
    <name>U1MZB0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01706</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89540">
        <property type="protein sequence ID" value="ERG89540"/>
        <property type="gene ID" value="J07HX5_01706"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968318_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="58" mass="6496" checksum="AEEE83E7DB5ED58D" modified="2013-11-13" version="1">MTYRDATHPNFYLMCDGTNCSNLYGISSIYTELELVRSDAEAAGWSCDDVADYCPDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZT5</accession>
    <name>U1MZT5_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable endonuclease 4</fullName>
            <ecNumber evidence="7">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nfo</name>
        <name evidence="9" type="ORF">J07HX5_01897</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="7"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89725">
        <property type="protein sequence ID" value="ERG89725"/>
        <property type="gene ID" value="J07HX5_01897"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025885_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="278" mass="29466" checksum="F76BFB2FEDE4B09E" modified="2013-11-13" version="1">MRVGAHVSIAGGVDNAVDRQQAVGGSCGQIFTTSPQVWREPTLTDEEVSRFRTDATEAGIGPWVVHASYLVNLATPKDDLREKSIASLQADVDAAARLGIEYVNVHLGAHTGAGVEQGLTNAASALDALEIPADVQLLVETDAGGGTKLGDEFSQFETVLTRSDQELGVCLDTAHVFAAGYDLATPDGVAATLAAFDDTIGLEALAYVHLNDSKHARGTHKDEHAHIGEGEIGESGMQAFLTHDAIRDLPVVLETPNEDDRGFEWNIDQTQLLADTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZW0</accession>
    <name>U1MZW0_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01764</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89598">
        <property type="protein sequence ID" value="ERG89598"/>
        <property type="gene ID" value="J07HX5_01764"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174517_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="78" mass="8454" checksum="4959383D92A34434" modified="2013-11-13" version="1">MGEILAENLSGKAVMGSDGAEMGQLYNITMDVESGRLANLVIEPEEVNATEYETDAAGRIQLPVSRVQAVKDRMIVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1N007</accession>
    <name>U1N007_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01819</name>
    </gene>
    <organism evidence="3">
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG89648.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
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        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
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        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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    <accession>U1N0B7</accession>
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            <begin position="58"/>
            <end position="79"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ERG89880.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="92" mass="9651" checksum="2CACC0BA852E6CEB" modified="2013-11-13" version="1">MISGRRKRGRHRLCGYTAASDAIGRQLPLIILSAFSGAAAYFLLVLVPSSGIGFTDVLVARAVGGAYTVGALSLGLTTLMRLTGGHGTWDDW</sequence>
</entry>
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    <accession>U1N0D0</accession>
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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    </reference>
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        </location>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="316" mass="34693" checksum="D15B2D12AFDC1409" modified="2013-11-13" version="1">MREFGFELGVCAKLERERDAIVSRQLGCGVHGQRVLDTVCIEPGPEFDERAAITAATIPAAAIESAIGPGRAQDPAAAFDCHPDRAAAAAETAVNTGFFERERRNGQTLVRQTVRYPDWIGRIVGIEHKPDLDRPGALETQLLTDTELGVLDAVVLATQSHVTGAHRNRIPDAVGIWRVDPATGEYEVLRAPSQLPTADPGIEIVDRGTSQTAIRHISPAEKQSLRRRIAERAYGKGWRTYDLPACAQVEPTDGLPYCPWKGRVVRPATECGPECDGHEPAPAPPVEQQRRRAEQTPWEPAPEGRRRQQSGLDRFE</sequence>
</entry>
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    <accession>U1N0H2</accession>
    <name>U1N0H2_9EURY</name>
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        <submittedName>
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        </submittedName>
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    </gene>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="69" mass="7626" checksum="BB1E024D172BC69B" modified="2013-11-13" version="1">MGDSTEKSEACGRCAMSSVSGVMDNDHDPFDGERIEVEEEKLRKLSPSVLLGRAKHRIDSVVTKLTYGR</sequence>
</entry>
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    <accession>U1N0P8</accession>
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    <reference evidence="2" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89883.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <end position="355"/>
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            <end position="372"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="382" mass="42480" checksum="6632E5C287FA900B" modified="2013-11-13" version="1">MNKNQRTQVKNNAQYLKQVRPIDPAEIAEYVEGRPHPAGVRQTLRESAPELGLRERSDGRFEPVADGPTTLAPVTQRLPEQYTRRIESLLVDQFGPGWPDGTSGDRLRATIREFKHQYLRGESVSYDKLTALGYLVYHLPAYFAAVQHVLAELAANDRLGHRVRVLDVGAGVGGPAVGLATALPEDVLVEYHGVEPSAAAEILETLLGETSRNVHTTVHRERIQAFEPERPFDLVCVQTCSRSWPTRRPWWSICSRRSPPTEPSQPLHRPTNGPQPNFERLSGRSRPAPMRRYTPQRSDSGRTRVQRASAGRSLSKSQSRPQSSSVSSIVASEPTAAQAATVRSSTPTSSSRTRCSGPTDDRRSRSHLTPDRSRRWPPPTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P369</accession>
    <name>U1P369_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="14944" checksum="B987F094589182E4" modified="2013-11-13" version="1">MSSDPEQERQNTDRVTVQTYIPAYQREQWDTHADDLGMSRSEFVRTMVQAGRRGFGAETTDQSTGGDSERMDTDLGTQVESVLAERQPLSWEELLGAIAGDIENRVETAVEELQDAGRVRYSGPKNGYVLEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3B7</accession>
    <name>U1P3B7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dihydrodipicolinate synthase/N-acetylneuraminate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00128</name>
    </gene>
    <organism evidence="1">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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    <sequence length="124" mass="12935" checksum="28AD781907EFF9C7" modified="2013-11-13" version="1">MTNALTNDTQFAGVYPAICTPFNGDGCIDYDQLRADARRLEAAGVDGLVPMGSTGESATVSHDEHIEVISTVAETVDVPVIGGAGSNNTREAVSLARRSADAGADGLLLISPYYNKPXXXXXXX</sequence>
</entry>
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    <sequence length="156" mass="16401" checksum="2A10130B2E188BED" modified="2013-11-13" version="1">MISEGDTIPSVTQPLVGEEIAPVSVRSLSDGPLVLAFFPGAFTSVCTHEMASLDERHDELIPAGGRLVGVSVDAPFALRAFRDELELSFALLSDSTRELVRACELTTDHEAVGVDEIAQRAVVVADSTGTVSYVDVVAPSTEPDYDALLAAVAATN</sequence>
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                <person name="Narasingarao P."/>
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    <sequence length="665" mass="75642" checksum="367BA9C926AB0DC2" modified="2013-11-13" version="1"> </sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88172.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="203" mass="23242" checksum="443EDF00A9AB39CC" modified="2013-11-13" version="1">MALGYPCMNRTLREGTPVRCNRSMQKQTWERDGLPYASELTLQNFQDLERILEWNVAHEIGFYRCTSELVPWHSQYELEALPDFPAIETAAQRCGELIDQHDIRFSFHPSHWVKLASQSDATVERGLTDLNNHGRWLDLLGLDRTPYYSINIHIGAKYDGKDATAARSVLRSTDLILPQKPLTSRRRHGXXXXXXXXCSATVP</sequence>
</entry>
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    <accession>U1P3T7</accession>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="366" mass="37609" checksum="89665E8DC4CAFF01" modified="2013-11-13" version="1">MSDQDCLAVRSHGYDLSRAWLVAAGTALTTVVGIVVAAKMIDLRTAWDAVVAADRRLLAGAVVVYLCSWLCRGRRYQLVLASTGRRCGVGFLTAVSLISQTINLVVPARAGDAVRAYLLSEYRAVPYPIGVASLVLERLADLVALAALGGVAVAWLRLGGQSVAINHPDMRWVGVGAAGATALLMAAFAVDRADRSVLPAVYSRVDGQRLPVLVRGIIESGQRVRGAVTDRQSLVAVTGWSLAVWGLDVGTALVILVALAGTPVPGDPTTIVLVATLAVGAGNLAKVLPLSQGGIGLYEGAVTGVIASLTPVSAGVALAVAVLDHGIKNVVTLLGGGAATAVLGRRPDQPGRPDDADTVETGPPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3U3</accession>
    <name>U1P3U3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00330</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88187">
        <property type="protein sequence ID" value="ERG88187"/>
        <property type="gene ID" value="J07HX5_00330"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1931848_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="131" mass="13682" checksum="6077C3DE9136080E" modified="2013-11-13" version="1" fragment="single">VLSPGVIRRGGGVWKRTVAAATRCGDRLTHTGFILSVLVNAVTSRTVDQCRSGDGLVPSFGSLPGCSIRGRVTSAPVLGPVWTQHSIMIQALEKTKSIENKPLTGLSVEVRGASDALSPTAEAVGFRATQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3Y1</accession>
    <name>U1P3Y1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00365</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88222">
        <property type="protein sequence ID" value="ERG88222"/>
        <property type="gene ID" value="J07HX5_00365"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129106_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="178" mass="20025" checksum="F2AF6EDB2871DEAB" modified="2013-11-13" version="1">MTDAQALVKTLDFQLDIQSDNESLLYDACHESRSVYNETIRLAKEGVDWDGIPDRVADDADLVKNTTQRVVAKALSAMENYYEYDDFGQPSHTKDGAYPLRANYEEGYNLSLTDDGDVAFRISAKPYKHVKGVLSGNDAHXXXXXXXTAICAWFLINNQYFHYRSAVDPCVCPLSFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P405</accession>
    <name>U1P405_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00385</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88242">
        <property type="protein sequence ID" value="ERG88242"/>
        <property type="gene ID" value="J07HX5_00385"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3411374_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="29" mass="2994" checksum="B219CDDB0EC23543" modified="2013-11-13" version="1" fragment="single">TASAPSPLSTDVDEEFVPGDYSYLSFAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4A3</accession>
    <name>U1P4A3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00476</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88332">
        <property type="protein sequence ID" value="ERG88332"/>
        <property type="gene ID" value="J07HX5_00476"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_20_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="16035" checksum="4CE258D6C35E901B" modified="2013-11-13" version="1">MVSPPASEESNFRGHVTQKGVVFTKDDDILLVRSDSENPWSIPGGRVQDGEDADEALKRELREETGLAVHVGQPVHAMTDLWFTADGEPMFTVVYDCETDESEITLNHEHEEYEWVSPAEATDRMPIEPLELAVKRAITRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4I3</accession>
    <name>U1P4I3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00552</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88407">
        <property type="protein sequence ID" value="ERG88407"/>
        <property type="gene ID" value="J07HX5_00552"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_534868_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="509" mass="53537" checksum="709A94DCC0E5BD44" modified="2013-11-13" version="1">MSSPGVSAAINNPGRSVRTAAGARAGLTETVFSEPPLTGVNEGAYSPAAGGPLTPTSARVSWRREPASCRRSLLPRRAATGSVVLCNPVDVHQHDLGGLHEPSEAGMSRERVTVDTDDASLRGTLRQMFALERDVLVLSMAMFAFSLGFQMTSRFLPEYLFALGGSGVIVGLYATVGNIIGAVYPYPGGAISDRVGSRSALTLFGLLSTLGFAVWLAAPAIGPITVGGLTVQPWVWVFVGLLFAQAWKSFGLGATFAVVKQATAPSRLAAGFASTETVRRTAFLLGPVLAAVLLGLSPSFTGGFQSVLAAGVVAGAVGTVAQHLLYDASEDSVGDTFEGLTQIRSDIRTMPAPLRPLLVGDTLVRFANGMVYAFFVLAVTQVYAVGFDQTIALAGVSYTVSLRPAAFFGYLLGVEMLVALVTMVPAAKLAERVGLKPIVAXXXXXXXXTPSPARRSSRSTKASLNNSSGMRLTGRLRTRPLSYLSTRSTRSLAPVTRMPTWKTGLLHSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4T1</accession>
    <name>U1P4T1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD/NAD binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00678</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88532">
        <property type="protein sequence ID" value="ERG88532"/>
        <property type="gene ID" value="J07HX5_00678"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="236" mass="26106" checksum="8D35B8BF519AA669" modified="2013-11-13" version="1">MTQTATVVDTYKLTPRVKGFRLRVPGTEFAYEPGQHTTIHFEAGGGEVVRPYTPTNLPGTDQLTLAIKRYDDGLASSYMHTRDPGDKVTIGPIDGDLTLADPSRDVAFLGTGTGITPLLAMARQYLREGTGNAHFVFGEKTEESIIHHATLNEFAAADSDFDVTFSLSDPEWDWTGRIGYVQEHLEELFDDFGSRDFYVCGVPQMVVDTKQKLRDLGTPDERIHSEGWEGSVVSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4T7</accession>
    <name>U1P4T7_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">J07HX5_00683</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88537">
        <property type="protein sequence ID" value="ERG88537"/>
        <property type="gene ID" value="J07HX5_00683"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036368_4_3_2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ERG88537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="211" mass="21922" checksum="D4D863CDA18A0A85" modified="2013-11-13" version="1">MTLVAFDFDGTLSNSEMTVLLGEQRGVADEMAKITERAMNDKLAYAESLRRRVGLLDGLSEAQAQAAFNQVRLRSGAGWLLNQLRAAGNTVVILTGGFERGVAAALAAAGVEVDAVVANQLSLANGTVTGTVTGPLVEGTKDDALAVLTAVYNRDLTRTVAVGDGANDRPMLKAAGHAIGYKPKAAVKPACDRTVSSMNQLTTVLTAAGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P4X9</accession>
    <name>U1P4X9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00733</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88587">
        <property type="protein sequence ID" value="ERG88587"/>
        <property type="gene ID" value="J07HX5_00733"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076812_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="69"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="237"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="287" mass="31212" checksum="BB6F74F96CB5A3C0" modified="2013-11-13" version="1">MNVADIMTPGEEVITVELPGTRDDVLEYLQDRAFSSVPVLKQTSDGHVYHGLVSRRTLIEHADEDQLAMLSETVTTISREASLAEAIELMTEAHERRLPVVEDDRLEGIITVTDAVRAIARGDIGVNTNTNISVEAVAGQEVNCVYAETPLPVGEQQLSFAGVPYAVVLDEAAKPTGMLTEEDVIAVARVVEGEDDTGESIANQDSEWSWEGIKAVGNSYLPTRNVEIPASPVAEFMTPELVTVGTHRTVRAAAQLLIQHKIEQLPMVSADHLEGIVQDMHLLEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5M9</accession>
    <name>U1P5M9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00983</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88837">
        <property type="protein sequence ID" value="ERG88837"/>
        <property type="gene ID" value="J07HX5_00983"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020884_3_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="255" mass="27730" checksum="FD53C12887961AB5" modified="2013-11-13" version="1">MAVHSDWGDWLLRAVERADPDELTVWYLGCNGFICKSAGGTTLFIDPYLGIGDPPRTVRMIPVPFEPEDAREADAVLATHEHTDHVHGPSQAPVVXXXXXXXSTPARSSCQSGESYQLGDLQVTVIEGNDPDAMDPVGYVVAAGSRIFVHVGDSRPGEFESVGTAYDIDLGAVAMGSSGMIPDKKTREPTLTTWYNDETAAVALARQLQLDRLVPTHWDMWKGLTADPSALHAHVDGFDFPRQLELAEIGDRLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5Q3</accession>
    <name>U1P5Q3_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ornithine carbamoyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00998</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88852">
        <property type="protein sequence ID" value="ERG88852"/>
        <property type="gene ID" value="J07HX5_00998"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_3_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="4">
        <location>
            <begin position="10"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="3">
        <location>
            <begin position="149"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="298" mass="31679" checksum="B2E7ADC6B620580A" modified="2013-11-13" version="1">MPASPSTPTHVLDIDDLSAADVTELLTLAARIKSGDQAPRLAATLAMLFEQPSTRTRVSFEAGIEQLGGTAVFLGPDETQLDRGEPIRDTARALSQYVDLIAARVADHDELVTLARYASVPVINALTDAAHPCQTLADLLTIREIHGDDTQIAWVGDGNNVCQSLTLGAALTGFDLTIATPAGYAIDDGVADRAATLGARPAETTDPAAAVADADVVYTDVWTSMAHKTDPAEKRHAFEGFQVTRELLGDRTLLHCLPAHRGEEVTDAALESGMSAVWQQAQNRLHAQNALLVWLGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P5Z0</accession>
    <name>U1P5Z0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01105</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88957">
        <property type="protein sequence ID" value="ERG88957"/>
        <property type="gene ID" value="J07HX5_01105"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055069_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="42"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="156"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="343" mass="38302" checksum="3A48B8A2C8971F79" modified="2013-11-13" version="1">MLVSHYFEWETHITGGHARSVSNQRTILERNNIAYTTSPTVNADLLHLNNMGPRSVLAARRARQADVPVLIHGHQTVADLRDSFRFFDTIAAVARPYLERAYSLGDRIIAPSAHTRDVLDSYTDVPKTVVSNGFDPTKLAGVDDPALRTEYRERYNLESPVVFMIGHVIERKGLQTFVETARAMPEVEFVWFGYLNPGGGTVDKLLRRRETTTLVQESPENCTFTGYVEDIRGAFAVGDVFFWPSHNENEGMALLEAMACGTASVIRDIPTYEWLTDGQHCLKADDNFLEPLRRLCADTDERNRIGENAATKATEFTLEAVADDLLGAYQSVTDEGVSVTPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1P645</accession>
    <name>U1P645_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gas vesicle structural protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01172</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the gas vesicle protein type A family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89022">
        <property type="protein sequence ID" value="ERG89022"/>
        <property type="gene ID" value="J07HX5_01172"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126378_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031411">
        <property type="term" value="C:gas vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000638">
        <property type="entry name" value="Gas-vesicle_GvpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018493">
        <property type="entry name" value="Gas-vesicle_GvpA_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00741">
        <property type="entry name" value="Gas_vesicle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00234">
        <property type="entry name" value="GAS_VESICLE_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00669">
        <property type="entry name" value="GAS_VESICLE_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0304">Gas vesicle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0926">Vacuole</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="147" mass="15416" checksum="D97971190AF14FEF" modified="2013-11-13" version="1">MRKQQPMSDPKPTRSQGDLAELLETLLDKGVVINADIAVTVGDTELLGIKLRAALASFETAAKYGLEFPSGTDMTRVRDEAELEQSPAPSAAADHDRTAADGGTQTVPESDLESGTEPVASGKETATPNKADRSGGSTDSDSERPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6D9</accession>
    <name>U1P6D9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01285</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89132">
        <property type="protein sequence ID" value="ERG89132"/>
        <property type="gene ID" value="J07HX5_01285"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140786_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="133" mass="15461" checksum="2B7EB63818A32872" modified="2013-11-13" version="1">MPDSLVEYLRQDMECEGLLQCLHGLKQLDRGCYQVLVETEEPLTVDAVADHVDRERSTVYRSIQRLLKAGLVQKDQVNYDQGGYYHVYYPTDPQQVADEMQRILNDWYAQMGQLIQEFEDQYEDRVEGPAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6G1</accession>
    <name>U1P6G1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01310</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89157">
        <property type="protein sequence ID" value="ERG89157"/>
        <property type="gene ID" value="J07HX5_01310"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099718_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="220" mass="23275" checksum="4030359D322CEB72" modified="2013-11-13" version="1">MSRQRQSQSQSKRPGAVRIGGIVFGRRELLDLAAAWLALALAFTFFIGLSGSPEKLTAFGTLAPTFLLSLIAVGTGFLLHELAHKVLAVRFGQVAGFRASYPMLGLAIASGIAGFLFAAPGAVYHRGRVTAREHGLIAVAGPVTNLGLTMLFVPFVVVPGLVGDIGRWGVLVNVFLAVFNMLPVGPLDGKTVRSWNRQVFWLVLATAAALAGLAAIWLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6R1</accession>
    <name>U1P6R1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01419</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89262">
        <property type="protein sequence ID" value="ERG89262"/>
        <property type="gene ID" value="J07HX5_01419"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2406231_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="9801" checksum="49570B044E984418" modified="2013-11-13" version="1">MSQQSIKMPEKPETATRQQSVTKIVVHERSQSEKNAKGIEWLGRGVVGLLMSGFVVIGAVAATRPVTGLGAAIVLSFISLYLLAALKTSSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6Z6</accession>
    <name>U1P6Z6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">J07HX5_01500</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="3"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89342">
        <property type="protein sequence ID" value="ERG89342"/>
        <property type="gene ID" value="J07HX5_01500"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_1_0_2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="7">
        <location>
            <begin position="7"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="8">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ERG89342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="239" mass="25434" checksum="977618166010F4CA" modified="2013-11-13" version="1">MTVLFVRASDIPAYVADGTADAGITGFDQARESGTELVELLDLEYGHCRLVLAAPEDSAVEQVTDIAGGTVATEFPRVTREYLDEQRIDAEIVEVSGATELTPHVDIADGIVDISSTGTTLRMNRLAVIDELLASSVRLFASPEAAADPKVEQTATALGSVLAADDRRYLMMNVPADRLEAVRDVIPGMGGPTVMEIAGTDQLAVHAVVDQHQVFETINALKTAGASDVLVTEIERLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P776</accession>
    <name>U1P776_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01555</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89397">
        <property type="protein sequence ID" value="ERG89397"/>
        <property type="gene ID" value="J07HX5_01555"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2101892_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="115" mass="12800" checksum="02F3D22A159ADCE4" modified="2013-11-13" version="1" fragment="single">RLYEYVEYKAAEYGITVEQVDPANTSRRCSHCGFTHPDNRESELFECLKCGYENHADYNASKNIGLRYLRRNQTGGDEGARIGVRLNSGMVTVNGEFSPAEVSARTGVHAESPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7B1</accession>
    <name>U1P7B1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00167</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88026">
        <property type="protein sequence ID" value="ERG88026"/>
        <property type="gene ID" value="J07HX5_00167"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1113840_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="249" mass="26967" checksum="3AC3B2C14AE2C6F3" modified="2013-11-13" version="1">MRFRRICQDTPLQPLPDPETPARLLNADTRRAFDWLTGPDGAECECQAQQANTGAFPGVPEPAGRISSEPLWGQQEWDRSKRGAASGAQPPAPGLPGRTRRAWVPPPGDPCDVRQPNTKNPGSDSSQHAQGRGTRLGQXXXXXXXDARVFPGAPSQLVESPASFSGASETGTVRNAARPVRLNHRTPGPQPNKTGPVSRHQATRMTSANQTRRTQDQTVLNTLGREELAWVKLARTELDWTLSPATGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7N9</accession>
    <name>U1P7N9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00299</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88156">
        <property type="protein sequence ID" value="ERG88156"/>
        <property type="gene ID" value="J07HX5_00299"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010289_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="Alpha_ANH_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022427">
        <property type="entry name" value="MJ0570_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="PTHR12196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039123">
        <property type="entry name" value="Diphthamide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03679">
        <property type="entry name" value="arCOG00187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthami_syn_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="237" mass="25462" checksum="F8F9DD3B333B2900" modified="2013-11-13" version="1">MNAWVSLFSGGKDSSWALYRAIEEDLQVERLVTVHPEGESYMYHMPATELASLAAESIGVPLSEVRPGAFADAADTGARGDAELEPLEEALETLAADLGGLAGVTAGAVESEYQTSRIRGMCDRLEADLFAPLWGEDPETLLRQMLTAGFEITVVRVAAAGLDASWLGRRLDADALTDLLALREQYGVHVLGEGGEFETIVTDGPHMDRPIELDGEPTYDGSRGRLQIDDAWLGAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7T6</accession>
    <name>U1P7T6_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_00349</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Potential transporter for phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Membrane</location>
            <topology evidence="2 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88206">
        <property type="protein sequence ID" value="ERG88206"/>
        <property type="gene ID" value="J07HX5_00349"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG88206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="392" mass="40346" checksum="041176D514C25345" modified="2013-11-13" version="1">MIGTVLLIGVVASLFVGFNIGGSSTGIAWGPPVGAGIIKKTTAAALMTFFVLLGGWTVGRNVMDTLSDGLINTELTLTAGVAVLFFIGLGILIANLFRVPVPTSMTTVGAIAGLGLATGTLNYEIIAEIVLWWIVTPVIGLWIGGAIGRYVYPAVNQRIDIEKSEGSLLTVNHDGTVPTPALGPNTTRTELLSTVAVLVIGCYMAFSAGASNVPNAAAPLVGGVDGLGDSTAIVVATLAIGIGGFTIARRTMESVGGELSDIPLLAALFVMTTASTITTLLSAIGIPISLVMATVMTIVGIGWGRATRPITIRDAVARDTDDRTITTGAITADGGESPPVAPIGEREPTDVRATGNLFNPRAIIKYISMWIIGPSVSTVLAYGFFIFFPGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1P7V2</accession>
    <name>U1P7V2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00369</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88226">
        <property type="protein sequence ID" value="ERG88226"/>
        <property type="gene ID" value="J07HX5_00369"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1975033_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13917" checksum="87524DC8BD3C1713" modified="2013-11-13" version="1" fragment="single">MLIFHSQIISSQNTFSIYNNVLLFCSVVTSGAAEYRQIAVTGEEALCPHWPPIERGARSWLVTETSNIRVLTIGQSSRIAERAPRPPHSTLVRPQIPATSSPARPEPHLGTDRISAALTARAEPEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P857</accession>
    <name>U1P857_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00465</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88321">
        <property type="protein sequence ID" value="ERG88321"/>
        <property type="gene ID" value="J07HX5_00465"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2299240_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="100" mass="10995" checksum="A0DBBDEDEF04C3AE" modified="2013-11-13" version="1">MPPTRNSTGGKRPTSDVRTHAEEISAQFSDHLDVSVDEIESKLQTLVDEYSVPLEGARRSVTSSYLGDAGMDRDELAPDSSELTLVGEIDTDEQWVDLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8J8</accession>
    <name>U1P8J8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00596</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88451">
        <property type="protein sequence ID" value="ERG88451"/>
        <property type="gene ID" value="J07HX5_00596"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165238_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="90" mass="10122" checksum="F5FB802574582ADE" modified="2013-11-13" version="1">MDDDRLRRALTAFEGSKTARRLVTRQAADLLASGRLETDLGIEPTIETVVRNMTDAPDGHGLIERWNWWVGALEFAYGGYLQFRVRVGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8R6</accession>
    <name>U1P8R6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00677</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="83" mass="9266" checksum="D89877A99E90B6B6" modified="2013-11-13" version="1">MPWHRRRDLEGGKELGVWLLVQDGTVERELYVESYEYRGGAFDVYTATPAGEWTQTGEYETVTAAFEAATAVIESSPHMLAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P8V6</accession>
    <name>U1P8V6_9EURY</name>
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        <lineage>
            <taxon>Archaea</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="189" mass="19883" checksum="4C058F92535380EE" modified="2013-11-13" version="1">MRSVPANAELALLLEVASTPTPGNVDRHHDHPDLTFEQFLAGAVGTRDGFKRAADGAPLGAAFERAIIGMSDQRGGNTQFGAVLAVTPLAAAAGRADLDLDRSGVRSVINGTTVDDTVAFYRAFDHVEVAVGAPPESLDDLDVRRGSQATPVIREEGLTLAALFAASTETDALAREWDQRFSAGVRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1P913</accession>
    <name>U1P913_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1">
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        <lineage>
            <taxon>Archaea</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="40" mass="4328" checksum="13B4576592FE3BCF" modified="2013-11-13" version="1" fragment="single">RLLDIAAQRGVREIVAAETGEYVKQPTSVQVRTADQLTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1P950</accession>
    <name>U1P950_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase or acyltransferases (Alpha/beta hydrolase superfamily)</fullName>
        </submittedName>
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    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
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            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="158" mass="17281" checksum="19A66D366F936F14" modified="2013-11-13" version="1">MPYTSRGGVSLYYEHERSGGETVVFVAGLGVGRWLWHWQREAFTDEYDLILPDNRGAGESDAGLSPFVAWLPESLRGLVLLKLAGYSISGMAADLEAVLADVGVDHAHIVGASMGGMIAQQYALEYDRAVSLALLCTTHGGETRCRSLRRRRHRCTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1P969</accession>
    <name>U1P969_9EURY</name>
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        <recommendedName>
            <fullName evidence="1">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]</fullName>
        </recommendedName>
        <alternativeName>
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        </alternativeName>
    </protein>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG88681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="142" mass="16523" checksum="70AE5E1D758C14B0" modified="2013-11-13" version="1">MKEATSAGAILFRDTRGRREYLLLKSRPGDWEFPKGGVEGDEELQQTAIREVEEEAGIEDFRLIDGFRQDYDYVFEASGTTIHKTVHLFIAHSFETSAELSNEHRDLQWRDYEQAINTITQDGPRNILRDAQTFLDDHPDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9Q7</accession>
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        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="protein sequence ID" value="ERG88846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="J07HX5_00992"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2406228_0_0_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="92" mass="9575" checksum="C83489E8D506B016" modified="2013-11-13" version="1">MIFVAPVFPSGHSWLAAHGQSGSLAVGSATVAYARDRFAGMAVWTRVRSAVIAGQRAYPGELPGNDEWTLTVMTAVYGCCLVGSSTGRTVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1P9W7</accession>
    <name>U1P9W7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01027</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88881">
        <property type="protein sequence ID" value="ERG88881"/>
        <property type="gene ID" value="J07HX5_01027"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112303_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="160" mass="17574" checksum="109C1C0FE37623A2" modified="2013-11-13" version="1" fragment="single">ADTAESVPFRTIWTAVLGYETAIERPYYALVNTDDDHPVGWLAREECKPGHVPAGESVFIVQASNDWSETHFEADPASVTDALATMTADIVDDARLATPAWTDTQRWRYALPEAGIESGPVESARDHGLYLAGDWVEGDARLHAALRSGLDTGERIAHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1PAQ7</accession>
    <name>U1PAQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01334</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89181">
        <property type="protein sequence ID" value="ERG89181"/>
        <property type="gene ID" value="J07HX5_01334"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075180_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="52" mass="5462" checksum="20868C5645606F64" modified="2013-11-13" version="1">MIQSEFRLGSGGPFAGASDWKGCLVVAAAVTSRGAQTESVDGFERGRDDRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB62</accession>
    <name>U1PB62_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Mevalonate kinase</fullName>
            <shortName evidence="11">MK</shortName>
            <shortName evidence="11">MVK</shortName>
            <ecNumber evidence="2 11">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mvk</name>
        <name evidence="14" type="ORF">J07HX5_01474</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10 11">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="2 11"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89316">
        <property type="protein sequence ID" value="ERG89316"/>
        <property type="gene ID" value="J07HX5_01474"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_0_0_2"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00217">
        <property type="entry name" value="Mevalonate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022937">
        <property type="entry name" value="Mevalonate_kinase_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="PTHR43290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="103"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="242"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ERG89316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="327" mass="33647" checksum="20924E234BFD35CD" modified="2013-11-13" version="1">MATSTAPGKVYLFGEHAVVYGEPAVPCAVQRRAEVSVKERSSGLRVQAGDLTLSGFAVEYDGAELSRPDVDAPDALVDAALGYLNEALAQARDAANAPRAGFDVVVNSDIPLGAGLGSSAAVTVAAIDAATRSLGIELDRTELAERAYQVESAVQGGQASRADTFCSTMGGAVRVEGEDCQTIDAPDLPFVIGYDGNAGDTGALVADVRNLRNNYAFAADTISAIGDLVRRGERRLTSDAQAELGRLMNFNHGLLSALGVSARSLDAMVWAARNAGASGAKLTGAGGGGCVVALDETDETLTALNYTPECETAFRAALDTVGVQENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1PBE9</accession>
    <name>U1PBE9_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01549</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89391">
        <property type="protein sequence ID" value="ERG89391"/>
        <property type="gene ID" value="J07HX5_01549"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1318489_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="208" mass="23846" checksum="394ED1D20B984D7C" modified="2013-11-13" version="1">MSTPVYTRLRRQMSEWIDLTQTLSEDSPTLPPLHPDVEYEDFATLAEDDYNSTILHVETHCGTHMDAPTHFLSKDSYRTIEEVTVDEMITEAVICDFTDKAPNEGVSRADLAKQAEQYDLSAGEYLIWDCGMAPADTDRYLRNFVYPEKRGRRVHGRTGDRLLCHRRVVGRQARRDARGTPRPLHTVARGYPDHRGRRQSRRRGAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PC57</accession>
    <name>U1PC57_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01848</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ERG89676"/>
        <property type="gene ID" value="J07HX5_01848"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187393_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="74" mass="8037" checksum="0C4878B941F17708" modified="2013-11-13" version="1" fragment="single">ASKTDIDRGLRLGTNAPMGPLELADHIGLDVVLDASATLATELGDRYRPAYLLKRKVEAGDLGKKTGRGFYEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCL5</accession>
    <name>U1PCL5_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_02003</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89831">
        <property type="protein sequence ID" value="ERG89831"/>
        <property type="gene ID" value="J07HX5_02003"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="26"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="484" mass="50892" checksum="05665A30E96168D2" modified="2013-11-13" version="1">MGTGATGLTRGHVIDGDEQSETEMDTDSITVVDPATERVVGSVPAGTESTVDAAVEAARDAVTAWDGMAPAQRGRVLSAIAARIRDRADELTDVLVSENGKAASSAASEVETAARYFEYYAGIADKIHGESIPQAGEYTDFTLQEPLGVTAHVLPWNFPVMLFGRTVAPALAAGNTTVVKPAEQTPLTATELTQLFQEAGLPDGVVNVVHGRGPGVGAPLAGHHGVDGVAFTGSVPTGREVAKQAVQNFNPVHIEAGGKNPNVVYPDADMEQAIDSTLTSIFTFNAGQVCSAGDRLLVHETIHDEFLDRLTAAVDELTVGPGATDPDVAPIVSEAQFDRVREYIQVGTAEAGTPVVGGEAPDRDGYFIEPTIFDGVSSEMRIAQEEIFGPVLAVLTFSDEQEAHALANDTQYGLTAGVHTTDVGRSLRFARAVDAGQIYVNEWFAGGVETPFGGYGMSGFGREKGLEAVDNFTQTKNVCLNIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCQ7</accession>
    <name>U1PCQ7_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase subunit of the DNA excision repair complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02028</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89856">
        <property type="protein sequence ID" value="ERG89856"/>
        <property type="gene ID" value="J07HX5_02028"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="80"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="258" mass="28825" checksum="E69E84897848728E" modified="2013-11-13" version="1" fragment="single">MINLLWGAGGWQLDLTPGLLCLCSVGVTVAVKALDTENILMAQRSGPLQPDRPDAESEFRVDAPFDPAGDQPDAIEQLAAGFRDGMDKQTLLGVTGSGKTNTVSWVLEEIQKPTLVIAHNKTLAAQLYEEFRTLFPDNAVEYFVSYYDYYQPEAYVEASDTYIDKDASINDEIDRLRHSATRSLLTRDDVIVVASVSAIYGLGDPDNYIDMALRLERGQQIDRDQLLAELVDLNYERNDVDFTQARFGFAVTPSRYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCV1</accession>
    <name>U1PCV1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">J07HX5_02089</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89916">
        <property type="protein sequence ID" value="ERG89916"/>
        <property type="gene ID" value="J07HX5_02089"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="8">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="7">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ERG89916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="379" mass="41081" checksum="DBA94AA3336E0F6F" modified="2013-11-13" version="1">MEFALSEDHQLIRDSVREFCEAEIEPIAQTIEDDHRFPDEIFDQLADLDVMGVPIAERWGGLGGGVLLYTLVAEELGRVSGSVGLSYVAHVSLGAKPIELYGTETQRERFLKPLAAGEQLGSWALTEPESGSDASSLNTRARRNGDGWRISGTKQFITNASVADTMLVKAVTDPDAGRDGISTFIIDPEQPGVEITTVWDKMGLNASPSCEVQLDNVTVGKDRLLGEPGAGWQQTHQSLVGGRISVAALSVGIARGAFEAARSYATDREQFGQPIGEFDAVRDMLVAMDRKIERARLLTQKAAVAQETGDDAARLSSMAKLEASETAREVAEDAVQVLGGYGYTTEFSPQRFYRDAKLMEIAEGTSEIQRLILGRKLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1PCV4</accession>
    <name>U1PCV4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_02094</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89921">
        <property type="protein sequence ID" value="ERG89921"/>
        <property type="gene ID" value="J07HX5_02094"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="36"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="367" mass="41392" checksum="2D29C63D18B0825A" modified="2013-11-13" version="1">MVEPSQTGEPERLQAYLTEQLDEQIVDTALLEAGLNRIFRVATADNPRAYILRQPDEGRDGAGFVDVHTEHAVLSRLEPTDVPAPTPVHYCDDASVLGTPFSIMEYAPGEPIGWDESLPVGYRTRSARDRVGQLLIDRLATLHSTNPERFDTVCDDVSLREQVDRTIGQLEAATSATTHDPVVLWRVADWLQETVPEQAEPRLVHGDYKPDNVLFRWVGRPTVAAILDWETATLLDPRTELGYFLFYWREPGDPTPDIDTVCERHPAVAADIRDRERAGFWPFTKAAGSPGRRMLVRRWEQATGTSYEHDRFYRAFGAVMLATVWEQLYATALERGETTTDPEREAHIEYVAALADAIRRGRLPLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>U1MHG6</accession>
    <name>U1MHG6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EMAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00905</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88759">
        <property type="protein sequence ID" value="ERG88759"/>
        <property type="gene ID" value="J07HX5_00905"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065946_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG88759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="107" mass="11441" checksum="EB14FC9AA86923D6" modified="2013-11-13" version="1">MVTSPFDLTVQVGEVHDAAPFPETNKTQMVKLWIDLGDEQVQSCAQLGYNHDPTTLPGQQVLCVTDLDSVRIAGFESEALTLGVPDAEGTPVLVTPTDTVPLGGELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MI89</accession>
    <name>U1MI89_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01241</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89089">
        <property type="protein sequence ID" value="ERG89089"/>
        <property type="gene ID" value="J07HX5_01241"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134823_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="146" mass="15911" checksum="0603163700AB5C2F" modified="2013-11-13" version="1">MNVLAPYDGSALAETAVKRAAEFDTGSEVIVVTVIPEDRRFALERGWVEEHETYDPAAIEDRFAQTVAEIAPAATFRAEYPEFSTPTIATVHDEIARTIRMVAHEIAASVVFVGSDNAGRVSTPVTSVGNPISKDPDYDVHIVRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIF6</accession>
    <name>U1MIF6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase, IS605 OrfB family, central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01332</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89179">
        <property type="protein sequence ID" value="ERG89179"/>
        <property type="gene ID" value="J07HX5_01332"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032903_3_5_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="4">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG89179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="140" mass="15796" checksum="2135EF067AAF2BC7" modified="2013-11-13" version="1">MIAFEDLTDIRERTGVSWGHEWAFNRLYEYVEYKAEEYGITVEQVDPANTSRRCSECGFTHPDNRESEWFDCLKCGYENHADYNAAKNIGLRYLRRNQTGGDEGAPVGVRLNSGMVNVNGEFSPAEVSARTGVHAESPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MIZ4</accession>
    <name>U1MIZ4_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01552</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89394">
        <property type="protein sequence ID" value="ERG89394"/>
        <property type="gene ID" value="J07HX5_01552"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2475872_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="87" mass="10175" checksum="40DD96A9F1510B3F" modified="2013-11-13" version="1">MTDELLIEGLRNDRYLKTLRLIEQFEDKIKLTLYEFNKAMTQHQPELFDSATGSGSERTRHQARGSRFTGSTTRWLVQRLRATTARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MJ67</accession>
    <name>U1MJ67_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADPH:quinone reductase related Zn-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_01664</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89499">
        <property type="protein sequence ID" value="ERG89499"/>
        <property type="gene ID" value="J07HX5_01664"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180502_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="2">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG89499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="96" mass="9982" checksum="A51CD6E3432226F5" modified="2013-11-13" version="1" fragment="single">MRAVVLTEHGGPSVLSVQDHDRPTPGADELLIEVHTASVNPVDTYFRDGSYPPVGLPFTPGVDLAGVVAETGTRVTGFDPGDRVYGAGIGNAEHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MV14</accession>
    <name>U1MV14_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMP synthase, PP-ATPase domain/subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_00051</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87910">
        <property type="protein sequence ID" value="ERG87910"/>
        <property type="gene ID" value="J07HX5_00051"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2629555_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="29"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG87910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="77" mass="7720" checksum="320ADC281131A91C" modified="2013-11-13" version="1">MVDATAFIDDAVEEIAAAVGDAEAVIALSGGVDSSTAAALAHKAIGDQLTPVYVDTGLMRKGETXXXXXXXTNSCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVI0</accession>
    <name>U1MVI0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein involved in cation transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00114</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87973">
        <property type="protein sequence ID" value="ERG87973"/>
        <property type="gene ID" value="J07HX5_00114"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2404395_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="PTHR12192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG87973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="93" mass="10523" checksum="188E439FC13F0000" modified="2013-11-13" version="1" fragment="single">MCWMFGYGSLMWDFAFTTTEQQRGTLRGYHRSFNKKSIQAWGTPETPGPVLGLEPGGECAGLVFRVPDAEHDTVVESLNEREGPSYDRHEELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVJ4</accession>
    <name>U1MVJ4_9EURY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diaminopimelate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_00129</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2"/>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87988">
        <property type="protein sequence ID" value="ERG87988"/>
        <property type="gene ID" value="J07HX5_00129"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_2_2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="3">
        <location>
            <begin position="248"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ERG87988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="380" mass="40176" checksum="61125BCEB9E721A8" modified="2013-11-13" version="1">MLDLDRVRTNYRRIAAAFLEADVMYAAKAHTGRAVLETLLDAGAAIECAARGELERAIAAGADPNELQYTAVNPPQADLTYAADLGARAPGLTVTAGAVDTFDRLAAQGYDGRVALRVNPGIGTGHHEKVATGKDAKFGIPAARAPAVAARLAAQFELVGVHAHVGSGVLTGELDDHIRAVERITEIARAVQNKAGNIEFVDIGGGFGVPYHENEPPLAVSTVADRVRAAFDLEAQLALEPGRYVVADAECILTRVNTVKQAPTATVVGVDASLATLVRPAMFDAYHPIRNVTTPDREPTPVSVGGPCCTSADVFCTDRPIARPERGDLLAVGMAGAYGYELASQFHSQPRPAEVAIDGTESRVVRRRETVTDVTRVERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVP1</accession>
    <name>U1MVP1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">J07HX5_00179</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88038">
        <property type="protein sequence ID" value="ERG88038"/>
        <property type="gene ID" value="J07HX5_00179"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058951_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ERG88038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="402" mass="43082" checksum="AA18C1323028B6D0" modified="2013-11-13" version="1">MQRPELLEGYLGDEEVAGAVRLGDDDVICFTPTRTLLYHGDGLLSDESVAVYDHDVSRVNIKNGRRKTTFELEYLAGTESFSVPSSKSKEVTTELLAGVLGACGITEPDESVLDVFRFSELTVVITDARLTKHVGAAVWSENYEEFLYDSVTNLEFEQGQVATQIVISTDGRPNRIKAPSDDAAVLRKTLTTALCEHYGVASASELAERIAPDQAPSDTPDDVAGVSFDDGITPLVEGKQGDNSADRTDGSLDSTDEPVSTAEADPDIGTTSGATETTDRDGSNRPTTAASQQPTTSPGGSETENTGHGDSDTEPHVRVKPDETSSVSALDDDEDQPQPQTQQASDDTVGSPTATSETAALTDADIAEVQTQLTELSEAVDQQTELLERQHETIRQLIEELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>U1MVS6</accession>
    <name>U1MVS6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00363</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88220">
        <property type="protein sequence ID" value="ERG88220"/>
        <property type="gene ID" value="J07HX5_00363"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101320_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="132" mass="15537" checksum="F6B66EAAD759CA87" modified="2013-11-13" version="1">MGEKRSSHTVYNVNYHFVWCPKYCHSILEHIEDSLEASFRDVCDEYGYEILSLHISPDHVHLFLSAHPKHAPSEIVRTVKSNTARKMWEQHETFLEEFLWGGGFWEESYYVGTASDVSTNTIEQYIERTEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXP8</accession>
    <name>U1MXP8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01056</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88910">
        <property type="protein sequence ID" value="ERG88910"/>
        <property type="gene ID" value="J07HX5_01056"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3336739_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="38" mass="4308" checksum="AE0CE90F56E18FA9" modified="2013-11-13" version="1" fragment="single">YLTWILEGLVEDDPRNVLEVDPETAALANTAIDRMLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>U1MXQ0</accession>
    <name>U1MXQ0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Coenzyme F390 synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00929</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88783">
        <property type="protein sequence ID" value="ERG88783"/>
        <property type="gene ID" value="J07HX5_00929"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_1_1_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="386" mass="41619" checksum="8F298BBB2649E1ED" modified="2013-11-13" version="1">MYDSETIADVCEQLTRVADHELYAEAFAEAEVDPDAVDSWDAFQDVPFTEPSDVAADIDANPPAGSLYEPGAMVTFSPLGDDLAPVVDTQADLAYEATVHATAFERAGVEPGDRVANTFGYHLFGTGEILQRGLEELGAEVFPLGPGDSEQAAELIAAYDINCLLGNPSFARKIGDQGATVETFIGAGEPFTSVPGYRDKIKTALGAETAVDYFGTRQFLPVAVETAAEDGLHVIDEYVIVELVDPDTGERLDPGQRGELVVTHRRKEGLPLVRYRTGDLAELERRGDELVLPDGVIGRTDDRLKVKGVKLYPKAIPSVLAGFDGLTGEFRLEVTREATDRLTVVCEGTADHKALSTALESRLLVSPDELRTVEEIGETGVVDSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1MY62</accession>
    <name>U1MY62_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine dehydrogenase related Zn-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">J07HX5_01262</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89110">
        <property type="protein sequence ID" value="ERG89110"/>
        <property type="gene ID" value="J07HX5_01262"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027399">
        <property type="entry name" value="ADH_N_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13823">
        <property type="entry name" value="ADH_N_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N_assoc" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="179"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ERG89110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="345" mass="35506" checksum="A9CCE714787D247D" modified="2013-11-13" version="1">MRAAVYHGPGDIRVESVEKPTIEQPTDAILRVTHTAICGSDLWPYRGESDRDVPSPIGHEPMGVVEAVGDAVRSVDPGDTVFAPFAISCGACEFCRRGLHTSCVNRGSWGGDNGGAQGEYVRSPHADGTLVRVPDRHADDEATLRAVLPLTDVMGTGHHAAVSAGVGPGSRCVVVGDGAVGLCGVLAARRLGATQIIAVGHHAGRLELAAEFGATETVLEDDETALETVRELTDGGAEHVLECVGAASAMETAAAVARPGGTVGYVGVPHGLGDGLDLFDFFGDNITLAGGVAPVRAYAEELLADVLGGTLDPSPVFDKTVSLGEVAAGYQAMDERDAIKVLVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYF8</accession>
    <name>U1MYF8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01359</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89205">
        <property type="protein sequence ID" value="ERG89205"/>
        <property type="gene ID" value="J07HX5_01359"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2127742_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="113" mass="11461" checksum="12F3012286923E1F" modified="2013-11-13" version="1">MFSEGVTADCEVVKMIVPPPPSAISAAAAFAQRNWPATRTSQAPARSSSVTERTPPPSVSVLDALLTSTSTWPNRSWICSNAAATATGSEISVGTASAVPGSVSVICAAVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1MYP0</accession>
    <name>U1MYP0_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-phospho-L-lactate guanylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_01301</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89148">
        <property type="protein sequence ID" value="ERG89148"/>
        <property type="gene ID" value="J07HX5_01301"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076569_2_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043814">
        <property type="term" value="F:phospholactate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02114">
        <property type="entry name" value="CofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002835">
        <property type="entry name" value="CofC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40392">
        <property type="entry name" value="PTHR40392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01983">
        <property type="entry name" value="CofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03552">
        <property type="entry name" value="F420_cofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG89148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="192" mass="20198" checksum="2D5E37C3118D6AB4" modified="2013-11-13" version="1" fragment="single">MRVLVPFDTQSPKTRLAPALDAAERELFAKRMLADVLAAIDATPHDPLVLATGPVETTTPVTQDERPLTAAVNAALADADKPVGVVMADLALVTPAALDRLFGLADGAEVVIAPGIGGGTNALVVDQPGFRVDYHGLSYRDHRRRAEELGATAAVVDSYRLSVDIDRPADLREVLLHADGSAAGWLEAAGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ19</accession>
    <name>U1MZ19_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01573</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89415">
        <property type="protein sequence ID" value="ERG89415"/>
        <property type="gene ID" value="J07HX5_01573"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768354_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="361" mass="39525" checksum="185CEE2C4629E4BB" modified="2013-11-13" version="1" fragment="single">SAHLAASDVQTLQFCSARQGAEIAAKQIVDAASEHPTAGYVETDPYHAGLGKQERRAVENKLKTEAADVVPTTNALELGIDIGSVDATVTAGYPGTKQSFWQQVGRSGRGTSNALSVLLGGMDAMDAYIFDNPEYLFADDSVEDAVVSVDNDRVYADHVLAAAAERPLRADDAAYFGTDQRFREIVEMWQDAGLLESVGDLDAGGVTYTGDRRPQSRLSLYGTGTTEFVVSCETGTIDHDPVAKERAYREYHEGALFLHAGQQYEVTTVDESGRHPTISVQETTTDEYTQTFSTKHIDELVVRDHTPLAGEYDLYFGEGTIRIQYDEYLVRNVFTGDVIRGPLPTEAPPLELQTELLWVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>U1MZ99</accession>
    <name>U1MZ99_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">J07HX5_01511</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89353">
        <property type="protein sequence ID" value="ERG89353"/>
        <property type="gene ID" value="J07HX5_01511"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1237253_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="223" mass="24332" checksum="EBAADBD1C533990B" modified="2013-11-13" version="1" fragment="single">TDISEQKQREQALKRQNERLDKFTSIVSHDLRNPLNVAMARLELATDECDSPHLDDVRAAHNWMEQLIDDLLQFARAGHGAIEHDHIDLRRLVREFQATGATDEAAVVVETEQTIRADRDRVRQLIENLIQNALDHGGTSVTVGDCDGGFYVEDDGPGVPEASCATIFEPGYSSTTDGTGFGLSIVKEVVDAHGWEIRVTGGADGGARFEITGVEPATGPEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>U1P346</accession>
    <name>U1P346_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase of the beta-lactamase superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00043</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG87902">
        <property type="protein sequence ID" value="ERG87902"/>
        <property type="gene ID" value="J07HX5_00043"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2202375_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="108" mass="11924" checksum="C03B36FDE840D828" modified="2013-11-13" version="1" fragment="single">MNYTVTPLHCGTLRLDKSILTTQVDSGVTVPVPSICYLIEGAHGPVLVDTSFGNIQQMEQLHPSFECSRSAGATVTSQLDAHGYQPEDIEVVVLSHLHWDHCYNLELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3D2</accession>
    <name>U1P3D2_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">J07HX5_00148</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88007">
        <property type="protein sequence ID" value="ERG88007"/>
        <property type="gene ID" value="J07HX5_00148"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1582844_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ERG88007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="168" mass="19013" checksum="C6370641EC0AF79F" modified="2013-11-13" version="1">MWRSLATGVNNPLDWQSTVYDASAQKIDQLCCRCGSHHRPGSETSQQPAPIDYRSHRGNHLEWILTVRRSPISVVGYTVQTSAIRAYHMNICYRWVSKTVNLRRRPHAHLNRWSQPVVHLPTAAHTRGPSESTRNIWTTDASIGRAPTCRGHSSHSAGQIVRRHPAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P3W6</accession>
    <name>U1P3W6_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_00350</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG88207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG88207">
        <property type="protein sequence ID" value="ERG88207"/>
        <property type="gene ID" value="J07HX5_00350"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_571890_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG88207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="460" mass="45671" checksum="6CFFAB14DE1A7A01" modified="2013-11-13" version="1">MSVPTATIPPTSARVIGVVAGLGAAVVGVHAPVAGAGALAGAIVVGILTRVTRANSSALLAVLLPVSALVTVGTLGGALTRSPLSLCLTAAMTLIGASVAVIVSGGGSAAQLSQIGAISRHVTVIALAGLLIALGIGSAGGAANTAGILGVIDTGPVGVVVVFLIAGIICGAGLLSLPFAMLMTPRYRHNAHDPQTTAAVIVAVVFGAVGCLVAVGVVVAGRPQVLVVNGWPVIRLFPVVATGVGVTLITAGQLTRYSWLKKERRPPVSPTLSFLGSLAGFVIMIVAILVFRGPQTAGGWVSLFGLVAGLAAGSWVLCLLCASKLRGSETQLTPSVAALLLCLSGVIVGAGAELTRVGFIGVGTDGLVALGAITAGLAVHQLGRFGRILGREVGAAGANRRPQLVRAGWVGLVSLFGIGVATAGIWLSSMFAPTLSVPATVVVVLAIIALRTGIRRLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6P1</accession>
    <name>U1P6P1_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">J07HX5_01397</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89242">
        <property type="protein sequence ID" value="ERG89242"/>
        <property type="gene ID" value="J07HX5_01397"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="114"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ERG89242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="330" mass="34986" checksum="EC788CE3729C6412" modified="2013-11-13" version="1">MSKTSESGTSTGRAGTTVVGELPGARRALLAGLGVVFWGYLLLRWSYDRFVEPDVNVINREPFVPTGPIEGAADALSSAESALGVVGTPVGWLAWLAEAATLGINNLPALAEGGLITVQITVVSILFGLVLAVPLAVARVYGGRVTRWVALGYTELIRGTPLLAQLFVLWYGLGWLGPTVRELPGVGVDGPLPTAAVVVAMIGFTINSSAYQSEYIRSALSGVDAGQLTAARSVGLSKLGGIRYVVLPQALRFAIPGWTNEFIYLVKYSSLASFITVPELFQRARNIGEDTFQFTEIYVVVAVFYLGFVLTTAAAMTIVENRTSIPGLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>U1P6U8</accession>
    <name>U1P6U8_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">J07HX5_01455</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KE356559">
        <property type="protein sequence ID" value="ERG89297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ERG89297">
        <property type="protein sequence ID" value="ERG89297"/>
        <property type="gene ID" value="J07HX5_01455"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3075181_0_0_2"/>
    <dbReference type="Proteomes" id="UP000053694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ERG89297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="52" mass="5256" checksum="8E1C662F182407C4" modified="2013-11-13" version="1">MDDTITSATLGAVVTVVTSLFLPGAPLLGGAVGGYLDRVTQPRGPVWALFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>U1P751</accession>
    <name>U1P751_9EURY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">J07HX5_01530</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">halophilic archaeon J07HX5</name>
        <dbReference type="NCBI Taxonomy" id="1325472"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Euryarchaeota</taxon>
            <taxon>Stenosarchaea group</taxon>
            <taxon>Halobacteria</taxon>
            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="364" mass="40370" checksum="6003C3EB6867D187" modified="2013-11-13" version="1" fragment="single">MSAQSTDERDIRVLLADDDEAWLRSTAELLERQRDRLQVITAATLADATARIDTAHNRIDCIVADYMFERTTGLELLRETRDRGFEQPFILVTGQGDETVASDAISQQVTDYIPKRSFGGRDESLARRIVTVVEQHRAEQALAVKQTSQNTILNILRQESSRADLAQRFCDHLTNERDYACAWIIIDETDTPTPQAVAGGDEYHTAVSQLPPAERQAEPTHRAQETAELTTVAPIAPSEEPGWRQAASDREFQAAIGVPIRSNESVIGSLGVYKPTPTVTQTEQELLAEYGESIGYALRSVEWRESLLAPGTTTIQIGVADVSVPLVRFLRQLPPDTTIEILTTVPQEETLLYVVELSGTTPTR</sequence>
</entry>
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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            <dbReference type="EMBL" id="ERG89637.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="61" mass="6717" checksum="2AB22C11E1D56290" modified="2013-11-13" version="1">MPAIELDFGDRQDMVQEQVSTPGVFVPGENERTIPVLSLLDPTDREVRLILGPVAKATRVV</sequence>
</entry>
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    <accession>U1P8U9</accession>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">J07HX5_02140</name>
    </gene>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
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            <authorList>
                <person name="Podell S."/>
                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
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            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ERG89967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="39" mass="4021" checksum="64617D727596372B" modified="2013-11-13" version="1" fragment="single">MAAVGLAWQFGARSLNAVAAPLVAAVVVGAVYVYWSDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2013-11-13" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>U1PB56</accession>
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        <name type="scientific">halophilic archaeon J07HX5</name>
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        <lineage>
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            <taxon>Halobacteriales</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
            <title>Assembly-driven community genomics of a hypersaline microbial ecosystem.</title>
            <authorList>
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
                <person name="Banfield J.F."/>
                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
            </authorList>
            <dbReference type="PubMed" id="23637883"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
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        </cofactor>
    </comment>
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    </dbReference>
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    </dbReference>
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        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="131" mass="13615" checksum="7518C91A5FA96A21" modified="2013-11-13" version="1" fragment="single">MAQSNKTMMQLGTAEAAPGAIDTGRLRIGEARDGAPVGLPVAVINGADTGRTLYIQAASDGDELNGVGVVRQLVPQLDPADLSGTILMVGIANLFGYRVGEHRNPIDDTKLNRAYPGNKKGSTTERIAAAT</sequence>
</entry>
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    <accession>U1PBU6</accession>
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    <reference evidence="2" key="1">
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                <person name="Narasingarao P."/>
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                <person name="Allen E.E."/>
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    </reference>
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    </dbReference>
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            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="127" mass="13786" checksum="309DC3671C610F02" modified="2013-11-13" version="1">MSEDNATRRSMLKRAGVAAVGVVGLAGMTGSAAANKDHTIEFRVADGDGDADYSCEVPDESPDCNGTLEQGDSKTEKDGYMKIEGHVDNGWEDIIHFDDSLDSNHFDWTVDDPMRVVVDSSIEHEAH</sequence>
</entry>
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    <accession>U1PC43</accession>
    <name>U1PC43_9EURY</name>
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        <submittedName>
            <fullName evidence="4">Signal transduction histidine kinase</fullName>
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    <reference evidence="4" key="1">
        <citation type="journal article" date="2013" name="PLoS ONE" volume="8" first="E61692" last="E61692">
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                <person name="Ugalde J.A."/>
                <person name="Narasingarao P."/>
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                <person name="Heidelberg K.B."/>
                <person name="Allen E.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="260"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ERG89661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053694"/>
        </source>
    </evidence>
    <sequence length="455" mass="50655" checksum="337BF4F10E7A033F" modified="2013-11-13" version="1">MYANEAYAELYGYDPEELVDEHCKLIYRDDDVRWIQEEVLPTVKNEGHWHGTPTGIHADGGTLVEDHTFATADEEELVCTVNSTKRNRRERAIEELHNTCQALIEAKTAEKIAHTAVDAFRDVLNMPVNAVYLHNEEQDQLVPVAWTDQAKVIIGDLPTFERGEGIAWTVFETGDARIYDDVSTRPERYNPDTSARGEVILPLDDHGVVMIGSDEAEAFDETDADLARTLATHVTTALDRVGREQTLKRQNERFDEFAQVVSHDLRNPLGVAEARVELAQEECESPHLDKATDALERSQALINDLLTLAQEGEQVTRLEPVELAGLVEHCWESVKTDQAVLEVEQIPKINADRSRLKQLFENLYRNAVEHGGNNVTVRVGTTDGGFYVADTGPGIPESEREAIFEPGYSTSSEGTGFGLRIVKEVVDAHGWGVAVTESKQGGARFEITGVEYTET</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>